ZOE Science & Nutrition - No.1 Protein Scientist: Are you eating enough? | Prof. Stuart Phillips & Dr. Federica Amati

Episode Date: July 31, 2025

Are you eating enough protein? This is probably a question you’ve asked yourself. With “high protein” labels on almost every type of food product you can imagine, it’s easy to get confused. I...n this episode, Prof. Stuart Phillips explains how protein can keep us healthy as we age. He also outlines when we should eat protein, how much protein we really need, and provides simple, practical advice to help you achieve it. Stuart is a professor in the Kinesiology Department at McMaster University. He’s the author of more than 400 scientific papers, many focusing on protein and muscle health, particularly during ageing. With so much confusion around this topic - especially in the context of fitness and ageing - this episode will provide clear, evidence-based answers from one of the world’s leading scientists on the topic, to help you make smarter nutrition choices. 🥑 Make smarter food choices. Become a member at zoe.com - 10% off with code PODCAST 🌱 Try our new plant based wholefood supplement - Daily 30+ *Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system Follow ZOE on Instagram. Timecodes 00:00 We’ve been lied to about protein 04:05 Why protein is completely different from carbs and fat 09:05 The depressing age when you start losing muscle 14:45 Your muscles have a secret second job 17:25 Why food companies are suddenly adding protein to everything 22:25 The shocking protein intake that fuelled your biggest ever growth spurt 26:45 Why the 'optimal' amount of protein is so hard to define 33:05 The surprising truth about protein for building muscle 40:15 Most of us are already eating the 'optimal' amount of protein without trying 42:30 When eating more protein could actually be harmful 45:00 The ‘anabolic window’ myth debunked 48:50 Why 'animal protein is superior' is an outdated idea 51:16 The myth of ‘incomplete’ plant proteins 51:55 The ancient food secret our ancestors discovered all over the world 53:50 Is there an upper limit for protein in one meal? 57:25 My number one food for a high-protein breakfast 59:05 A simple pyramid for choosing the healthiest protein sources 59:55 The 'healthy' protein source that’s a class one carcinogen 01:02:55 When a protein bar is no healthier than a chocolate bar 01:04:30 Why your protein cookie could be reducing your healthy life years 01:06:20 My number one tip for health (and it’s not about nutrition) 01:08:50 The ideal daily protein target for most healthy adults Studies: Optimizing adult protein intake during catabolic health conditions, 2020, Advances in Nutrition Integrated myofibrillar protein synthesis in recovery from resistance exercise with and without multi-ingredient supplementation in overweight older men, 2019, Frontiers in Nutrition Higher dietary protein during weight loss: muscle sparing?, 2018, Obesity  What is the optimal amount of protein to support post-exercise skeletal muscle reconditioning in the older adult?, 2016, Sports Medicine  📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Free resources from ZOE Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

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Starting point is 00:00:00 Welcome to Zoe, Science and Nutrition, where world-leading scientists explain how their research can improve your health. Are you confused about protein? I know I am. Am I getting enough? How often should I eat it? Is high-protein ice cream a good idea? If you've heard answers to some of these questions, whether on social media or from your workout-loving friend, there's a good chance these originated from research carried out by today's guest. Professor Stuart Phillips Stuart is the world's leading expert on protein, with hundreds of peer-reviewed papers to his name. Have you heard that you need to eat protein straight after you work out? Stuart wrote that paper.
Starting point is 00:00:53 Have you heard that there's a limit to how much protein you can absorb? in a single meal. Stuart wrote that paper. Have you heard that animal protein is better than plant protein? Stuart wrote that paper too. But here's the thing. Science progresses, and Stuart has been carrying on research for 30 years now. As his research has continued, he's changed his mind on a lot of it, but the world has been slow to catch up, and now he's decided to speak out. We're also joined by Dr. Federica Amati, head nutritionist here at Zoe, scientists at Imperial College London, and the brains behind Zoe's new personalised guidance on protein intake. By the end of this episode, you'll know once and for all how much protein you need each day,
Starting point is 00:01:37 along with answers to the most contentious questions about protein from the world's leading expert on the topic. Stuart, thank you for joining me today. It's a pleasure, Jonathan. And thanks for having me. And Federica, thanks for being here. I'm so excited about today, Jonathan. Can't wait. I think we're all excited about this one.
Starting point is 00:01:58 First, we have to get through our traditional round of quickfire questions. And, Stuart, I've heard that you have listened to this podcast, so you know what's coming. Sure. We've designed this to be really difficult for scientists. You're ready to give it a go? Yeah, go for it. Brilliant. Stuart, is the protein that we consume mostly use for our muscles?
Starting point is 00:02:18 No. Federica, are most of us deficient in protein? Not most of us, but some groups are at risk. Stuart, can protein help keep you healthy as you age? Yes. Federica, could some people benefit from protein supplements? Yes, but quality is important. And back to Stuart.
Starting point is 00:02:40 Does it matter when you eat protein? Maybe. And finally, Stuart, you've been researching protein for decades. Is there anything that you've changed your mind on as new data has emerged? There's lots of things I've changed my mind on, but I think the big one is that plant derived or plant-based protein is not inferior to animal-based protein in terms of supporting health and definitely muscles. I think all of those quick-fire answers are super interesting, and that's partly because I know that we get an enormous number of questions about protein
Starting point is 00:03:16 from our listeners, and I think that's partly because there's enormous amount of conflicting advice online. But it's also partly because big food companies have started to plaster their products with labels saying high in protein. And as a result, lots of people are saying, well, so I guess I'm deficient in protein, am I getting enough? So I'm incredibly excited to have both of you on here to hopefully clear up a lot of questions.
Starting point is 00:03:43 Stuart, you are one of the world's leading researchers on protein with 100. hundreds of peer-reviewed papers on the subject. And Federica, you've been leading Zoe's own position on protein, which I know incorporates a lot of Stewart's research in order to provide personalized protein guidance to Zoe members. So I can't think of two better people to hopefully clear up some of this confusion. But before we talk about exactly how much,
Starting point is 00:04:08 Stuart, could you actually help to explain why protein matters at all? The clear distinction I like to make is that for a good, carbohydrates and fats, they're fuel, for the most part. There's a small requirement for fat to be a structural element of cells in our body, but protein is the structural component of everything. It's skin, it's bones, it's your heart, it's your lungs, and clearly it's your muscle, but it's part of your brain too. So it's a substrate. It can also be burned as fuel, although not very much. So that's, I think, the key part that distinguishes it from the other two macronutrients. can you help us to understand a little bit more why do I need to get it in food what happens when
Starting point is 00:04:51 I eat it where does it go yeah sure so protein is made up of building blocks and we call these building blocks amino acids and the amino part comes from the fact that protein contains nitrogen it's the essential nuclei that differentiates it from carbohydrates and fats which are basically carbons hydrogens and oxygens there are 20 different amino acids and we require we need to get them from our diet, nine of them. And of those nine essential, we call them amino acids, there are groups that have various functions, but we can produce the rest. So the need for protein is really the need for those essential amino acids, which are degraded and excreted in urine, hair, nails, your feces. So our requirement for protein is really about replacing essential amino
Starting point is 00:05:43 acids that are lost. Yeah, and I love to think of amino acids essentially as building blocks, as he said. And it's amazing when you see the way the amino acids then connect and fold makes proteins. And those then, as Stewart said, go to form skin hairnails. Also, it's an essential part of your immune system. Your immune system relies on protein to create immunoglobulins to get ready for inflammation or to get rid of an infection. So a really important thing. And this relationship between essential and non-essential amino acids is also important because our can use essential amino acids, like taking Lego bricks apart and then build up the non-essential ones. So if you're getting enough variety of amino acids in your diet, apart from the essential ones which you have to get through food, your liver is able to build the others and then make any protein need from that, which is really cool. Like the liver is super smart. It's a very clever organ. I'm just thinking about all the parties at your house as you're watching YouTube and proteins folding. Don't know whether I'm going to quite be able to convince my family that
Starting point is 00:06:43 that Saturday Night Entertainment. Probably Stuart at your house, this is Saturday Night Entertainment. It used to be when my boys were young enough to appreciate Lego blocks, etc. But not so much anymore. Brilliant. So there are like 20 of these different amino acids. These are sort of the Lego bricks that I used to build up the proteins for everything inside me. And as a human being, I can't make all of those from scratch. So nine of those Lego bricks I need to take in. But the other 11, I can like make myself. Yep. Now when I think of protein, I was thinking about this last night. I immediately think of my 17-year-old son.
Starting point is 00:07:18 And he's like, well, I need to eat steak so I can put on more muscle at the gym. That is the link for him. It's totally clear. And everything that he's seen on like, his, you know, social media channels are all about, you know, as a 17-year-old boy, how you put on more muscle. And it's very exciting for him as well. Because the truth is that, like, I go to the gym and I try really hard not to lose muscle. He goes to the gym. And the next day, it's just like there.
Starting point is 00:07:43 It's totally unfair. I'm sure there'll be some listeners who can understand that. But I know that in your research, you're not just focused on sort of young people, people looking to weight lift or look beautiful. But actually, you've done a lot of research on protein in older adults. Could you help to explain why protein is important for health and quality of life as we age, not just like if I want to put more muscles on? Yeah, I mean, I think it would be fair to say over the 28 years that I've been at McMaster University, I started out and we just looked at young people. We were interested in making their muscles bigger. So much like your son or university age students. And we learned a lot about what we can do in terms of protein. But the key stimulus for growing muscle, if you're younger or if you're older about preventing the loss and I'm squarely in that category as well, is to lift weights. So resistance. exercise or loading is the most important part. When you're a kid and you're growing, you're under the influence of lots of growth factors, which, you know, linear height and then broadened
Starting point is 00:08:52 chest and all these things which your son is experiencing and the fact that he's lifting in the gym, two thumbs up. When you're older, of course, that growth stimulus is gone and at a certain point, and it's probably depressing to mention this. It's probably for most people, it's in their 30s. They begin to slowly lose muscle. And this age-related. loss of muscle is a condition if it's problematic that we call sarcopenia. So time marches on. Research becomes me search because I'm interested in what's happening to me. And I also direct a center where we have 500 community members coming in, essentially,
Starting point is 00:09:30 to exercise, and the average age of them is about 72. So, you know, I'm talking to these folks, why you're here, why are you exercising? Well, I've heard it's important, et cetera, and the story goes on. And so, yeah, lots of important benefits associated with hanging on to muscle, but for the protein standpoint, supporting that lack of muscle loss and supporting all of the other physiological processes that Federica mentioned about protein requiring processes that are important in older people too. Yeah, it's so important in older age to have functional ability and to be functionally able, you have to be able to get up of your chair, get out of bed by yourself. And muscular skeletal mass is essential. So how healthy your bones and your muscles are, and especially the muscles that help the skeleton get up. So not so much they're like good-looking muscles, but the functional muscles, they're the ones that we want to maintain.
Starting point is 00:10:20 Because as we get older, that's where you really see the difference between being able to live independently and having to need help to do your sort of normal daily routine. So I think this is where a lot of the interests come from in how do we maintain this functional ability in older adults. And muscular skeletal mass is super important for that. And so is protein and muscles only about continuing to have strong enough muscles to sort of be able to get out of your chair or to be able to get out of bed or like to not fall over or does it play any other role? I'm asking a bit Federator because you talked about, for example, like your immune system and. Yeah. As Stuart mentioned, we can't store protein. So whereas with energy, we store it in our muscle tissue. We also store it in our liver. We store it as fat in our
Starting point is 00:11:07 fat cells. So we have lots of lovely energy stores to tap into when we need them. But if you don't have enough protein in your diet, then essentially we can't really get it from anywhere apart from breaking down our muscles to get that protein. And we do that because the immune system needs protein, because other functions, enzymes which catalyze all of the reactions in your body are proteins. So what happens is your body then starts to draw protein from your muscles to help with the other processes. You see this a lot, Jonathan, like thinking about the life course in low-income countries where there isn't access to food, the biggest killer for children under five is protein malnutrition
Starting point is 00:11:48 because our bodies cannot cope without enough protein, right? And so when we think about why we need to be aware of the importance of protein, it's because it's involved in so many processes. Because of that, our body is amazing at absorbing it from food, by the way. like we're super efficient at absorbing protein from either small intestine and like making the most of everything we eat. But yeah, it's essentially a really important part of health generally. If I'm not immediately getting it from food, I'm going to sort of strip it out of my muscles in order to carry out all of these critical things like fight my cold or whatever it is.
Starting point is 00:12:23 And so if I'm not getting that protein, then basically I'm going to strip down those muscles. And so this is one of the reasons that I might lose. muscle over time if I'm not supporting it? Yes, and you see examples of this in two big groups. So one is people who have rapid weight loss. So like GLP1 receptor agonis, if we don't support people that take these drugs with exercise and correct nutrition, their body will use muscle to get protein. And then the other big group is cancer patients. So patients who are undergoing chemotherapy, cancer is a very metabolically active disease. And so it will get protein to support the immune system from your muscles. And this is called cancer cakexia, so this loss of muscle
Starting point is 00:13:06 mass and cancer patients. It's like a really, it's a big problem, actually. It's a big predictor of survival for patients. It's like muscle is a labile reserve of amino acids and protein. And despite what people think about its importance, as Federica mentioned, it is the tissue that essentially will give up its amino acids for more critical processes. There's a concept in aging and this concept of muscle loss and sarcopenia that muscle is sort of like a functional reserve. So in times of being challenged, whether you're sick or during COVID was a great example when older people were hospitalized. And, you know, it was a real struggle to survive. And as Federica mentioned, skeletal muscle in those times is a particularly important organ. And
Starting point is 00:13:53 almost the more you have of it going in there, the better your odds are survival are. It's funny. I'm completely reimagining this in a way I hadn't understood before because I think everybody listening probably is very familiar with the idea that the fat on their body is a store of energy. We all know that if you haven't eaten any food, then you know that, in fact, that's where you're getting supported. And we know that human beings can live for a long time, right, without food as long as
Starting point is 00:14:17 they're getting water. But we know that you lose fat and weight. I had never understood before that I could think about my muscles not only as mechanisms to move around with, but also. So you're sort of saying it's the only place I can store this protein from one day to the next? Yeah, I mean, I think that that's the odd part about protein that people maybe fail to recognize is that, you know, we're very good at storing fat almost an endless capacity. Too good.
Starting point is 00:14:42 Unfortunately, we have limited capacity to store carbohydrate, but our liver and our muscles are two great sites where we do store carbohydrate. But there's nowhere to put protein and sort of stock it away and use it at a later time. So you either ingest it and use it, or you pull the nitrogen off, you make urea, ammonia, you excrete that mostly in the urine, and then the rest of the carbon skeleton that's left over, you burn it as fuel, or sometimes you can make it into glucose. I like to say, you know, if you're stuck on a desert island and you had no protein, you wouldn't last long, but, you know, we can live with a minimal amount of carbohydrate and fat, as long as we have some protein, we won't be super happy, but we'll survive.
Starting point is 00:15:26 Can I just ask for a second about that conversion of protein question because that came up a lot as well because we're now surrounded by products that say added protein and they're often on very highly processed food and the argument basically is like, well, there used to be fats and sugars in this, but now I've got protein and so this is presented as it's all the win. But I think I just heard you say that if I eat more protein than I need, it can end up getting burnt and used as calories. Could you just explain that for a second? You know, the 70s and 80s were characterized by fat was bad, carbs were good, and so we took fats out of a lot of foods, and we created very carb heavy in a lot of situations replaced it with sugar. It was a true disservice to, you know, the food supply system. Then it was almost like it sort of swung back and all of a sudden fat was okay and even saturated
Starting point is 00:16:18 fat was okay. And so, you know, the keto diet reemerged and almost like a phoenix. And now there's been a bit of a push, and I'm sure we'll talk about it, about the recommended dietary allowance in North America, the recommended nutrient intake in the UK, lots of different recommendations that are probably too low, in my opinion, on a few others. And so the pendulum becomes, well, we need to get protein because we're not getting enough. But that's not the message. It's actually, you know, a lot of people are getting more than enough.
Starting point is 00:16:51 but maybe there are more people than we thought who aren't quite making it. So now the pendulum swung the other way. And as you point out, Jonathan, I think that we've overcooked the message a little bit. And we've got products that, you know, protein water is the greatest example of, you know. I like protein ice cream. Yeah, protein ice cream. Three thirds of a tub for 10 grams of protein. It's awesome.
Starting point is 00:17:15 Yeah. Well, it's a pretty good ice cream to protein ratio. But yeah, it's odd to see protein appearing in places where. where I don't think it has any business belonging because nobody's truly and in our society's deficient in protein. There may be a few people who are just a little bit under what I think is the recommended intake, but I certainly don't think that, you know, it needs to be put into a lot of the foods where it's appearing.
Starting point is 00:17:42 Thank you, Stuart. And if I come back to this question about like what happens if I'm taking more protein than I'm going to use right now, because I had assumed that basically, if I didn't need it, it was just coming straight back out the other side at no cost. But I think I just heard you say something else. Yeah. So I think that there are some nuances in here. So the key point is that the nitrogen is pulled off of the protein structure.
Starting point is 00:18:07 And we make urea for the most part and ammonia. And that's excreted for the most part in our urine. So people say, oh, you pee protein out. It's not really that you pee the protein out. You pee the nitrogen out. But once you've taken the nitrogen off of the amino acid, it ceases to be an amino acid and you either burn it, it's oxidized, so it yields energy, or you can, in occasions, you can turn it into glucose. I think that it's true, however, to say that the efficiency that we do that with is not particularly good.
Starting point is 00:18:42 So as opposed to carbohydrates and fats, which we are very efficient at burning, we're not quite as good. at burning amino acids. So it's not that it's completely inert. You don't use it. You can, but maybe not with the same efficiency as carbohydrates and fats. And I think that means it's not zero calorie though from the perspective. I just want to make sure this is clear. Protein is four calories per gram, kilocalories per gram, just like carbohydrates are with plus or minus a little bit. So yeah, of course it's energy. And, you know, when we look at everybody's dietary intake. It's not like protein. We sum it all up and we just put a big zero on the bottom. For every gram, it's four kilocalories worth of energy as well. I think you're saying
Starting point is 00:19:30 that seems totally obvious. And I was completely shocked because I think the way that it's presented is more like a vitamin. It doesn't count. You can get more of this thing you really need as opposed to, by the way, if you're not going to use it up because you're not doing enough exercise today, then your body, as usual, is going to figure out very efficiently how to burn it, and therefore your total calories in the day is up. And ultimately, you know, if you're, like many of us, like just fighting not to put on weight, it's not going to be your friend, is it? I think that there's a little bit of a nuance to that message. We're not quite as good at burning protein as we are at burning carbohydrates and fats, but it's certainly not a free pass. In other words,
Starting point is 00:20:15 if you over-consume protein, you are over-consuming energy. The hard part is to figure out, do you actually gain fat? And I know you've had Christopher Gardner on here. He's a good friend and a colleague, but I kind of surprised Christopher with a paper showing that if people consume more protein, they tend to gain a little bit of muscle, not a lot, and they don't gain as much fat as you might think.
Starting point is 00:20:37 They still will put on weight, but not as much as you might think. And I think that that's the sort of, oh, you can eat as much protein as you might think. you want, it's totally, it's not a problem. And the answer is, like the answer to most interesting question is, it depends. What I'm understanding now is protein is definitely more than just like building my son's big muscles, that we need it in order to live and function for like every part of our body. And it's also really important, you know, in order to live these long and healthy lives. I think this then brings us on to that key question that all of our
Starting point is 00:21:14 listeners had like how much. And I think you've already mentioned, right, there's a lot of debate on this topic. Now, Stuart, you know, you've published hundreds of papers around protein. So I'd love to get your view and you can maybe explain how that's contrasted with what you described about sort of historical recommended daily amounts. Maybe just starting with sort of healthy adults, what are your recommendations for protein intake? Sure. I think the beginning point for this is to talk about what we call in North America, it's the recommended dietary allowance or the IDA and the UK recommended nutrient intake. It's usually about 0.8 grams of protein per kilogram of body weight. And everybody wants to know, you know, is that ideal body weight? It's just per
Starting point is 00:21:58 kilogram of body weight. From my perspective, I think that's a little bit too low. I think it should be closer to about one, maybe as high as 1.2 for older people. But I do think that the benefits of protein probably stop a lot sooner than a lot of people are making out. You know, when you were first born as an infant, in the first year of life, you doubled your body weight. And what do you think your protein intake was to support that? I'm assuming enormous amounts of protein at this point. But remember, you're very small, right? So grams per kilo, it's actually sort of about 1.2, 1.5, something like that. So at the time of your life that you experienced, the biggest and best growth you ever had, you did it with a pretty low protein intake.
Starting point is 00:22:42 Is that breast milk that you're describing to us? Yeah, yeah. Nature, nature's got it right. Yeah. That's a fascinating way to start with it. Some of our listeners won't realize, but this is a really charged debate. So if you're really into nutrition science and you talk to a lot of people, this is one of those areas where people get really worked up about this number. I feel that there will be a set of people listening to this and saying, oh, but
Starting point is 00:23:07 those numbers, they're clearly too low. And I think about like my first experience going to the gym and my trainer, I was in my 30s already. I'd never lifted anything. He was like, okay, well, one of the critical things you now need to do is eat two grams per kilogram in order to get any benefit. Why is there this debate and where does this come from? And why are you so confident, and maybe also why, on the other hand, you feel that 0.8 number was too low. Maybe just give us a bit more of this, because I think that will help us all to feel confident in the answer. Sure.
Starting point is 00:23:43 It is charged. I think that there's a lot of people who, myself included, have invested a lot of time into doing investigations and sort of looking for the answer to this. I think, you know, starting out with the recommended dietary allowance, recommended nutrient intake. So it's established with a method called nitrogen balance. And it's essentially exactly as it sounds, the balance of nitrogen, which is that we've, you know, already decided the essential thing that makes protein, protein, or amino acids, amino acids. And it's how much you take in all your food and all your drink and how much you excrete.
Starting point is 00:24:18 And so I do think, and I could be wrong here, that I may be one of the few people who's still active in doing protein, who's actually done a wonderful nitrogen balance experiment. And we collected everything. We collected urine, we collected feces, we did sweat washdowns on people after they had exercised. It's so much fun. They're delightful studies to conduct. And the balance of nitrogen should be, if your protein in and out, should be zero. The problem with nitrogen balance is that from a physiological standpoint, there is nothing that I can say about your physiology when you're in nitrogen balance. and there is this issue of if we give people more and more and more protein that the balance of
Starting point is 00:25:04 nitrogen gets increasingly positive, which should mean that you're retaining more and more nitrogen. We've already said we don't do that, so we can't really explain why that happens. We've got some ideas, but those two, I'll just call them observations to me, really indicate that the methodology is not particularly. good. So, you know, fast forward to 2025, we've got some methodologies now that I think are better. The problem is, in science, is coming to some degree of agreement about how good those methodologies are. And I'll be honest about that. So not everybody agrees. But we do have
Starting point is 00:25:47 some observational studies looking at people's protein intakes. And if they are a little bit higher than the RDA as people get older, they tend to have better muscle mass, they tend to have better mobility, they tend to be a little bit stronger, and they maybe have a small survival advantage. But is it so high that the protein intakes that are twice the RDA are better? I don't think that's the case. So the RDA, I think, is too low. Higher than the RDA is better, but how much higher? That's really difficult to determine.
Starting point is 00:26:22 And I think it's the difference between what do you require, i.e. need, and what is optimal? What is better? And, you know, nutritionally, to give you another example, I'll say it the British way, vitamin C, not vitamin over here, but vitamin C was recognized for a long time for its ability to obviously prevent you from getting scurvy. And, you know, who wants to get scurvy, right? No thanks. But the recognition was that consuming more vitamin C over and above what you needed to prevent scurvy was good and that was added to the intake to say this is good you get better immune function smokers need more but that extension hasn't happened for protein and there's probably lots of reasons for that not the least of which would be the disagreement about how we replace nitrogen balance as a method to determine protein
Starting point is 00:27:18 requirements. That's super interesting. I think what's also important is that our ability to maintain nitrogen balance changes over our life course. And when we're challenged with lower protein intake, our bodies become more efficient at maintaining the nitrogen balance. Because protein is so important, our metabolism adapts to make sure we get what we need. And so actually there is also evidence to show that we get a few of decrease protein availability in the diet. if you're under the age of 65, you still have this metabolic flexibility to maintain nitrogen balance with lower protein intake. You've used this word nitrogen balance both of you a couple of times, and I haven't followed the link between that and the amount of protein. Can you just unpack
Starting point is 00:28:03 that? Well, so in simple terms, it's protein in minus protein out. So if protein in is greater than protein out, it means that you're retaining protein. So we can forget about nitrogen and just call it protein if you want. If protein and protein out are balanced, we're good. Like we're eating the right amount and we're excreting the same amount, all good. The negative situation, protein out is exceeding protein in. We're losing protein from some pool. Chances are we're losing it from muscle, I think as Federica has already said, cancer, weight loss, GLP1-induced weight loss, for example. And I think in those situations, you have to realize is that muscle is lost, but then maybe some other processes and leaning on a term called adaptation are being sort of downregulated
Starting point is 00:28:52 and we're able to then come back into nitrogen balance because we have this amazing adaptive capacity to withstand if you like lower protein intakes probably again realizing the essential nature of protein for normal physiological function so if i'm in protein balance which was your nitrogen balance. Does that mean I am getting all the protein that I need? That's correct. In situations where maybe I am getting less protein, my body might make adjustments so that actually it can now cope with this lower level of protein. I'm in balance. So you're saying both of you, actually I've not really got a problem. It's like I've sort of become more efficient somehow at using this. For some time, right? But then if you prolong that and you don't have enough protein for too long,
Starting point is 00:29:41 then do you start to run into troubles where you don't get enough protein? But your body tries really hard to maintain balance for as long as it can. Some of the studies I've seen is like about six weeks. Is that about right? Yeah, I mean, we reestablish when we're in negative protein balance, we reestablish zero protein balance pretty quickly. And so what that means to come back to the Lego building block analogy is that the processes that are using those building blocks have kind of slowed down.
Starting point is 00:30:10 And you probably have a period of time where you're flexible and you can withstand that. It's not a big deal. But if your protein intake goes too low for too long, then that's when these adaptive processes become, if you like, an issue and you begin to tap into proteins that are in your muscle and maybe immune function gets a little bit lower. But, you know, I think that it's probably fair to say that the RDA is pretty good. call it a baseline estimate. And I'm not suggesting that it's two, three, four times the RDA, which I think a lot of people are out there saying this is where you need to aim. But it's at least, I think, about 20 to 50 percent higher than what most people recommend. I'd love to talk about different groups now. Maybe firstly, are there particular groups that are at more
Starting point is 00:31:03 risk of not getting enough protein and where these numbers of sort of you were saying 1.2, is too low? Yeah, so as we mentioned earlier is children. So children have a high protein requirement. So where there is no access to food, children at real risk of protein malnutrition. I will say again, this is really only really seen in low-income countries. So children in the UK and the US, luckily have access to food to get enough protein. And then later in life, it's after the age of 65, you start to see that there is this increased
Starting point is 00:31:36 requirement for protein intake. And it's a combination of, as Stuart said, like sarcopenia, so muscle mass loss, reduction in appetite. Also, we become a little bit less efficient at absorbing it, a little bit less efficient at like getting it into the tissues needs to go into. So the whole picture then means that actually increasing that recommendation in these groups is important. And then within older people, those who have chronic illness, so people who have a higher requirement for their immune function, if they have higher inflammation levels, that also requires. additional protein. And we've touched on cancer patients, which is actually a group where not enough protein can actually be the difference between life and death quite a lot of the time. Yeah. Those groups, I think have I missed anyone? No, I think that's a pretty good summary. You know,
Starting point is 00:32:23 to come back to Jonathan's 17-year-old son, the belief there would be, of course, because you're gaining so much muscle is that somehow protein is going to, you know, be the limiting step for that. You know, we've done a lot of work in this area, and I can say with pretty good confidence that the big driver, and by big, like, capital B-I-G, is lifting weights. Like, protein never really limits your muscle gains unless you're preparing for bodybuilding competition. So they're desperately trying to lose weight, but they're trying to hang on to their muscle. And, you know, that's a scenario.
Starting point is 00:32:59 But it's not the scenario that most people are in. And so let's just say weightlifting is the big thing as opposed to the protein. I was just describing the scenario when I first went to the gym and my trainer says, you know, you need to eat two grams per kilogram. And it's not like he just made that up off the internet. So this is like very strongly embedded in a lot of physical trainers. So I'd love to discuss a bit more. When does this cutoff come to? So what is the number that you are saying if I'm going to the gym?
Starting point is 00:33:30 And is that like if I'm going to the gym? times a week? What about if I'm going every day? Like, what is the number that actually you should be hitting? Yeah. So to be really, really clear about this, going to the gym and lifting weights if you're trying to gain muscle or if you're older and trying to prevent the loss of muscle is the categorically the primary stimulus that's going to result in muscle growth or retention of muscle as you age. Protein helps, but the analogy I like to use, use is that lifting weights bakes the cake and protein is that thin layer of icing as delicious as it is across the top of the cake. Or maybe it's even the sprinkles on the icing, I'm not
Starting point is 00:34:15 sure. So it's a small dressing on top of that. If you're, you know, one of these hardcore folks and you're doing CrossFit and you're hitting the gym three and four times, maybe you do have an increased requirement for protein. There's a lot of wear and tear that goes on in your body that you probably need to replace some of those damaged proteins. And I think it could be as high as about 1.6 grams per kilo. So that's twice the RDA. And I know a lot of people will say, wow, that sounds like a lot, but recognize that it's much below the 2 grams per kilogram or traditionally the 2.2 grams per kilogram,
Starting point is 00:34:53 which the bodybuilders would say is the almost folklore-ish level of 1 gram per pound. And when we talk about overcook concepts, then you ask me about things I changed my mind on. And this is one. We performed two what are called meta-analys, where we looked at a lot of the literature. And I remember one student of mine, he came back and he showed me, and I'm like, that's not much at all, like for the extra muscle. And it really was one of the, I don't know, it was an epiphany moment, but it was this gradual realization that a lot of what I'd been cracking the whip on, I'm like, I don't think that's actually right. And now, you know, it takes time to undo learnings, my own included.
Starting point is 00:35:39 I've tried to get the message out that it's probably overdid it. But now the, you know, the horses out of the stable now. And so things have sort of gone radically off in terms of recommendations and intakes. And I think without any good science that backs it up. Are you saying by far the most important thing is like how, hard I'm working in the gym. Absolutely. For determining my ability to put on these muscles. And as long as I'm not sort of really, really deficient in protein, actually it doesn't make a very big difference. You know, if I was eating one gram per kilogram, I'm probably still going to get a lot of
Starting point is 00:36:18 the muscle gain from the gym. You may get all of it at one gram. It might take you a little longer, But I'm actually, you know, the thought experiment is how much difference that number makes. And I'm, you know, I'm sheepishly saying it maybe not as big a deal as we once thought. And you're saying it sheepishly because if I'd interviewed you 20 years ago, you would have said, what would you have said 20 years ago? The younger, maybe better looking version of me, less wrinkle definitely would have said, no, no, Jonathan, you need to get, you know, this intake and it would have been at the higher end. I'm less and less convinced that's the case.
Starting point is 00:36:53 and more with the aging population where they're retaining muscle and, you know, everybody's sort of, you know, aging wins, and it's the question of whether you age like this with muscle or you age like this. And you only require a little bit of protein to make that happen. But once you begin to lift weights, it's like, it's the magic that makes you really hang on to muscle or if you're a young person to gain muscle. So if you're not going to the gym, there's like no magic to like eating muscle. more protein than most people have. You're not going to get any benefit. If you are going to the gym regularly, so I think you were saying three, four, five times a week. Well, the recommendations are two sessions of resistive exercise. Your 150 minutes is, that's the WHO. It doesn't matter where you are in the world. That's universal. So, you know, you've got to do both. I'm more of a lifter than I am a walker or a runner, but you definitely have to get both to get all the health benefits. And if you want to get like the optimal return out of that effort, and I have to say, as someone, I don't love going to the gym.
Starting point is 00:37:57 So I do feel like I'm definitely doing it for the benefits. You're sort of want to get. You're immortal. You're doing your state. I'm doing that. Then you're saying getting up to 1.6 grams per kilogram, if you're really working out that much, we'll get my optimal benefits on muscle. But actually what I'm hearing is like if I was down at 1 or 1.2, it might be a very small
Starting point is 00:38:17 difference. And so I shouldn't obsess about this versus other things. I don't want to put words in your mouth. I'm just trying to make sure I've understood. I think that's a pretty good summary. I mean, the other analogy I've used is, you know, you dip a cloth in water. And every time you turn it, the water that comes out is a benefit. So this is you going to the gym, the first sort of three, you know, lots of benefits. And the last little part here is that's where the protein comes in. And you've got to twist it pretty hard and you get a few drops out. And that's the protein layer on top of all of this. Can I ask one last question on this? Yeah. Which is your own diet. So you do still go to, you do still go to the gym. I can tell that you work out for people on audio. You know,
Starting point is 00:39:02 Stuart is in much better shape than you might pick up from his self-deprecating comments. Yeah. How many grams a kilogram do you go for? I'm probably around 1.3 to 1.4 on most days. I definitely don't focus on protein. I do have a protein heavier meal, which like a lot of people is probably, you know, your dinner time or suppertime meal, your last meal of the day, give it the global definition. I think about it, but I certainly don't, you know, weigh things or or obsess about it. I'm definitely a very mediocre athlete slash whatever, and I'm a mere mortal these days. I'm not training for anything other than to age well. And we haven't talked about one important thing is that the majority of adults get around 1.2 to 1.4 grams a day without trying. Like our diets have protein in them. But at the end of the day, most of us who are eating enough food, and I have to stress that. So if you're getting enough food, you're getting about 1.2 to 1.4 grams a day. Like that's the average for US and UK.
Starting point is 00:40:07 This actually came up, I think, in one of my podcasts with someone said to me, you know, when you do exercise, do you? find you're hungrier? And I was like, oh, I do. And they're like, what happens when you're hungrier? And they're like, do you eat more food? And I was like, yes. And I assume out of this, just as a consequence of what you're talking about, that I'm going to eat more total amount of protein as part as this. Yeah. You're nodding. This is where Christopher Gardner and I, good friend, we agree to disagree on a few things. But he makes a great point. And it's a good one to sort of maybe keep in mind, you know, he's at Stanford University, so big U.S. University and in North American football players.
Starting point is 00:40:46 So they eat a lot of food. I mean, these guys, they're big men. They're eating at, you know, three, four thousand calories. And even if you ate, you know, 10% of your energy intake at that sort of caloric intake as protein and as big as these guys are, they're hitting, you know, 1.7, 1.8 grams per kilo, like without even trying. But Christopher's Fond is saying is that, you know, there's a lot of protein supplements and everything. So then they are into the 2.3, 2.4 grams per kilo range, none of which I think is useful or doing anything for them,
Starting point is 00:41:20 but other than reinforcing the belief that that's what they need. But it's almost without trying that it happens for, you know, very active people, particularly those that are, you know, trying to sort of bulk, if you like. Also, I do think, to your point, a lot of people face. they're in this group. A lot of people think they're pro athletes or that their requirements are super high. And it's really a very small percentage of the human population that has these specific requirements for very hard to obtain goals. Earlier you said Jonathan, if someone's not active, if they increase their protein, will that do any good? Not only will it not do any good,
Starting point is 00:41:56 right, because it's not going to grow muscles for them if they don't move. It could actually be doing harm, especially in midlife. So what is quite consistent in the literature is that if people between the age of 50 and 65, get more than 20% of the caloric intake from protein, they're actually at higher risk of chronic diseases, especially cancer. So if you're essentially not active at all and you're in that midlife zone, increasing your protein intake with supplements or just because you decided that stakes are the best food in the world, like you could actually be doing way more harm than good. If you were confused about protein before you started this episode, you can be sure that your friends and family are in the same boat.
Starting point is 00:42:36 So why not share this episode with them now? Then they can finally understand their own protein requirements to support their health as they age. I would like to move shortly into like how do I turn all of this into practice for real around lunch. Before I do that, there are also lots of questions around sort of the timing and spread of protein. And I think that's also again encouraged by all of these big food manufacturers sort of suggesting that I need to have protein in. everything now. And thinking back also to my first experience of going to the gym, I realized also, as well as the two grams per kilogram, the other thing that you said is you absolutely need to eat protein. I mean, I'm slightly making this up, but I feel like within 10 minutes of leaving the
Starting point is 00:43:16 gym, because otherwise all of that hard work would be completely wasted. I'm cringing because that was probably me telling you that at some point. Is that it was your research from 20 years ago? To some degree, unwittingly, I think we've contributed this narrative. It's not just me. I'd name other names, but I'll let them remain innocent for now. Well, now I'm having the opportunity to sit opposite you, Stuart. So what is the advice around the timing of eating protein compared? Because you've already said, like, you have to do some exercise with something heavy. Yeah. So, you know, priority one is we got to go to the gym. If we don't do that, as Frederica mentioned, absolutely spot on. Nothing happens when you eat more protein. People talk about a satiety effect.
Starting point is 00:43:59 I'm pretty lukewarm on that that happens unless you really ramp up your protein. So, you know, let's sort of forget about that for now and say, go to the gym, then your daily protein intake. I like it in that 1.2 range. We can agree. Most people hit that. Some people don't, but most do. After that, the timing is this sort of, you know, and I hate to use the in the margins expression
Starting point is 00:44:26 or, you know, majoring in the minors. It's one of these other, it's the last little twist of the cloth that you might get a couple of drips of benefit out. But it's certainly not something that would make me say, you know, immediately post-exercise, you need to get your protein. That concept, which was given the name probably about 15 to 20 years ago, the anabolic window, was tied more to the replenishment actually of muscle glycogen, which is muscle-stored carbohydrate. than it was to protein metabolism. But a lot of us did some work in this area to try and see whether this was true. And there's a good friend of mine named Sean Arendt,
Starting point is 00:45:09 who's down at the University of South Carolina, and he's written a paper called, instead of the anabolic window, it's the anabolic garage or garage door. So it's open for a long time, and it's really, really big. In other words, it's probably open for about a day or a day and a half. So I could go to the gym first thing in the morning, eat very little protein until the evening.
Starting point is 00:45:35 And if I ate something with lots of protein then, then I would still get the benefit from the exercise I did that morning. Good to go. Yep. Wow. You can tell my train is straight after this. I know. I know. And I know as soon as I've said that, I'm like, ah, am I going to upset some people now?
Starting point is 00:45:51 Yeah. All the post-workout shakes. I know. And I run into these people. And they're like, I heard you on that Zoe. And I'm like, it's just science. I'm just telling you the science. Stuart, can I try the counter then?
Starting point is 00:46:01 Sure. Sure, that's like fine. But like you're working hard and you want to get the best benefit. And so actually, why wouldn't you take, you know, the extra few percent? Yep. So what if he said that? Would that change your advice? And I think that's the rider, you know, had the privilege of working with some very
Starting point is 00:46:22 good athletes. And, you know, for them, it is. It's all about the detail. details. And so putting a metal around your neck and standing on a podium is not who this advice is for, who it might be sort of more pragmatic to begin the so-called recovery right away. And I get that. I understand it. For most folks out there in regular society doing regular things and just hoping to stay a little bit healthier, that type of detail and nuances, I think. It's an inefficient message. The big one should be, just get enough protein, go to the gym.
Starting point is 00:46:57 continue, carry on. I'd love to talk about protein sources now. Yes, I was about to say. Federic has been very patient. Very patient on this, exactly. You told our researcher that this was something that you changed your mind on during the course of your career. Could you tell us sort of where you began and where you are today? Yeah, I mean, I think it's pretty self-evident. There are two, what I'll call the major scoring systems for protein. Essentially, they come down to how digestible the protein is, so there's a digestibility issue, and how many of these essential amino acids each protein has. When you look at it from that perspective, animal source proteins would be superior. In other words, they would have a higher score than plant
Starting point is 00:47:46 source proteins. And everybody goes, oh, well, game over, you know, it's got a higher score. They're the winner easily. And that was me, 25 plus years ago. Fast forward, soy protein was the main plant protein that we had probably 15, 20 years ago. And we noticed that's just not a whole lot different than it's usually dairy-based proteins that we're converting and comparing. And now we're in a world where you've got access to a lot of plant-based protein sources. And the diversity is extraordinary compared to what it was 25 years ago. and we're beginning to conduct experiments, and we see very little difference between what happens with plant source proteins and animal source proteins.
Starting point is 00:48:36 I would say that these are purified protein sources when we study this, and so we haven't studied whole diets. Well, actually, that's not true. We have, but I can't tell you about that yet. Have me on in another year, I'll tell you all about it. Definitely. Yeah, and I think it's fair to say that when we do that. that, you know, even exclusively vegan diets are, if you're judicious about how you plan your
Starting point is 00:49:01 protein, you're covered. The closer you get to the RDA, however, and the older you are, then it could be problematic. And I think we've sort of agreed is that those are populations for whom we probably need to pay attention anyway. So plant-based diets are, you know, just, it requires a little bit of planning, but for younger, middle age, especially active people, the differences between plant source and animal source proteins is, like, it's trivial, another deep in the margins issue, in my opinion. Yeah, and this is, so we're talking about quality earlier in the quick fire questions.
Starting point is 00:49:42 So the experiments that Stewart's referring to are like soy protein isolate, way protein isolate. See, this is it like the pure protein. But when we then look at the protein package, when we think about foods, it's a combination of plant foods that then provide this digestible, indispensable amino acid score. I'll bridge it down. They actually provide the same score as, say, a chicken breast, right? So the key is combining plants that then gives you this really good score. And then we take a step further and we think, okay, when we're combining plants, so when we're eating like legumes and nuts and seeds, you're not just getting those amino acids, you're getting the fiber, the bioactive compounds,
Starting point is 00:50:25 the complex carbohydrates, which you don't get from the protein package in an animal protein. So actually now we're in a place where there's so much evidence, and this is very getting excited, right, that shows that if you switch some of your animal protein to plant protein, you're actually prolonging your life, you're increasing longevity, you're decreasing your risk of chronic disease because of this protein package that plants come in. People say that plants are incomplete proteins, their poor quality. That's not true. The science is very clear.
Starting point is 00:50:54 The importance of combining plants is where the magic happens. Yeah, if there's a myth to be busted, and Federica just touched on it, and I hear this a lot too, and Christopher Gardner would tell you all about this, is that people say plants are deficient in these, and they're not. They might be low in certain amino acids, but they're not deficient. In fact, it's really hard to find a plant source protein. that is deficient in amino acids. I find it fascinating to go around the world
Starting point is 00:51:25 and I'll call them food insecure regions or regions where there's not a lot of animal protein consumed. Regions of Southeast Asia, India, South America, the Caribbean, everybody figured out that a grain and a legume together were good. I'm so glad you're impressed because I tell that to my undergraduate students and they just glaze over and look at me in. I think that's fascinating.
Starting point is 00:51:48 Could you help to explain it? Because I also slightly glazed over, as you said. Could you help me to understand what you just said? It's the magic of food synergy. It is. It's incredible. I mean, it can only be that so many people in disparate geographic areas of the world have figured that out because there's an evolutionary pressure for it to happen,
Starting point is 00:52:05 like you survived. And so I'm trite when I say this, but the undergrad seemed to resonate with it, is that grains are low in an essential amino acid called lysine. Legumes are pretty rich in lysine, but they're low in amino acids that contain sulfur. There's two of them, methionine and cysteine. But grains are high in those, and when you eat them together, you're good to go. You get the lysine that you need. You get the methionine and cysteine that you need.
Starting point is 00:52:37 And so this is like mixing, like, beans and... It's my beans and rice. It's lentils and rice. Barley and lentils. It's belt and your bolotti beans, right? So another thing that we've had a lot of listener questions about is the idea of an upper limit of protein absorption per serving. Is there truth in this?
Starting point is 00:52:56 Do we need to spread out our protein intake? Oh, we contributed to the noise in this one. We can absorb a lot of protein. I mean a lot, like hundreds of grams. And so there's no sort of upper limit on absorption. But we did publish a paper at one point that showed that when you ate, 20 grams of protein, that was all that your body could efficiently use. When we doubled the dose and we went to 40, your body used a little bit more, but it was by no
Starting point is 00:53:30 means double the response. And so everybody walked away saying, oh, well, 20 grams is all you can digest and absorb. And that's not the message. You can digest and absorb a lot more. Your body just can't utilize it. And from when I say, utilize it. I mean, your muscle couldn't utilize it. So we probably confused some people with that, but people have taken and run with the concept. But we can eat a lot of protein. I think Federica, you mentioned, is that we're very good at absorbing protein. Rarely does it not get absorbed. And there's a little bit, but as we get older, it does go down. If I ate lots of protein in one meal and not a lot later, actually, that is going to deliver all the protein I need
Starting point is 00:54:16 form, like my muscle growth and everything else over the next day. So this is like 20 grand. This is more to do with some sort of optimal thing. But actually, I'm getting, I'm going to be able to use it all. Yeah. If you ate it in one big meal or you ate it in three meals, I don't think there would be a lot of difference. I think the advantage would go to the three meals. We do have a study going on that. And so again, a year or so from now, we'd probably be able to give you the answer. But the truth is, you can digest a lot of protein. It's not capped out at 20 or 30 grams. Now, Federica, we have a lot of our older Zoe members who ask for advice on how to eat adequate
Starting point is 00:54:54 protein without having to eat more food than they find actually they have appetite for. Do you have any simple tips for them? Yeah, increase nutrient density foods. So make sure that you're eating foods that provide essential protein and essential nutrients. So when I think about this, I think about things like beans and tofu and nuts and seeds and great yogurt. They're very nutrient dense, so they don't take up too much volume. When you have reduced appetite, that can be really helpful. I would love now to actually turn all of this advice into really clear, actionable advice about what I can put on my plate. Maybe start with that,
Starting point is 00:55:32 like the healthiest sources of proteins. What should our listeners be eating? Look, I mean, the traditional protein sources, everybody, I think could rhyme it off. They probably first say eggs, meat, poultry, fish, great sources of protein, lots of other nutrients in there. Awesome. I think eggs have been on the dirty list for too long. I think there's still a pretty good source of protein, affordable, lots of good nutrients in there. But I think we can now begin to talk about plant source proteins, so legumes, beans, pulses, these sorts of things as a bio-equivalent form of protein. You might have to eat a little bit more, but probably not much. so much more that you would worry about it.
Starting point is 00:56:16 I think a meal where people, I don't say under-consume protein, but it tends to be carbohydrate heavy is breakfast. And the trend these days, I'm sure it's the same in the UK, US, Canada, it doesn't matter, Australia, is that there are lots of ultra-process foods that are available at breakfast that really are doing everybody a disservice. I like to teach students that if we shopped on the outside, side of the grocery store, up the produce aisle, meat and dairy, grains, and stayed away from the middle where all the good tasting, highly addictive.
Starting point is 00:56:55 High protein cookies. Yes, exactly. The protein ice cream, protein water, et cetera, we'd probably be a lot better off. So we eat real food, whole food. From that standpoint, then, I do like to talk a little bit more about protein at breakfast. My super food at breakfast is Greek-style yogurt. So a little bit higher in protein than the regular yogurt, probiotics, and it's a good breakfast food, throw some nuts, throw some seeds, throw some fruit in there.
Starting point is 00:57:25 It's probably my go-to breakfast just about every day. Yeah, and if you have Greek-style yogurt and you add 200 mils of kaffir, kefir is exceptionally high in protein, actually, then as Stuart said, you have two teaspoons of chia, the protein and fiber powerhouse plus omega-3 ALAs, some nuts and, some fresh berries, you have got yourself between 20 and 30 grams of protein in that breakfast in a regular-sized bowl. And it's such a great way to start the day and sit back to your point about eggs. Eggs are great for breakfast too, right? And if you combine those with a bread that has whole grains in it or even like a pumpernickel style bread, you can add some beans to that,
Starting point is 00:58:04 you've got a great breakfast that packs protein, other biactive nutrients and fiber at the same time. So I think pivoting to thinking about how can we include not only protein, but also fiber, also probiotics, like so fermented foods, all these things, then go back to this protein package. How can we make the most of these meals? And I think what's important to know is if we think about protein in a hierarchy of health impact, okay? So like at the bottom you have these plant-based proteins. That should be the majority of where we get our proteins from whole grains, legumes, soy products, nuts and seeds. And Federica, we said this word legumes and pulses off.
Starting point is 00:58:40 Yeah. Beans and lentils. Chick peas. Yeah. Peas, green peas. Navy beans. Edomami beans. But if you think about it, that's the majority of a protein, then the next level up is kefir, yogurt. So fermented dairy is a great source of protein and it's good for us for lots of other reasons. Then the next level up for me is oily fish. Oily fish are the healthiest animal protein. So they have the omega-3 ALAs. They are consistently shown to improve longevity, cognitive function. They improve a lot of things. Then above that you have eggs. So eggs are good for us. They're just not quite as good as fish, in my opinion, for a protein source. And then above that, you have white meat. Right at the very top, occasionally, you have red meat and kind of off the pyramid to the side and should not be a
Starting point is 00:59:26 source of protein every day is processed meat. I'm quite alarmed by the rise of like beef jerky and other processed like salamis as like a healthy protein source. Processed red meat in no world is a healthy protein source. Processed red meat is a class one carcinogen, and it's consistently shown to be detrimental for health. So it should not be a daily protein source. So I think think about it in that order of how well is this going to serve me for longevity and for decreasing my risk of the long-term chronic diseases that really we're all trying to avoid it, right? That's, I think that's a good, I've made that pyramid up, but I love it. I have no issues with that pyramid. I'll say about jerky is that if you're worried about your sodium intake, it's
Starting point is 01:00:08 stay away from jerky. I think what's interesting is that while the amount of protein that you're suggesting is higher than I think, you know, it has been the standard guidance. It's interesting that it still seems to line up very much with what we end up covering a lot on this podcast around like the ability to eat that with a diet that's really supporting your gut health and things like that. So I feel that's actually very positive. I would like to directly talk about protein supplements because I think that
Starting point is 01:00:38 many people jump to protein supplements and again like when I first went to the gym the consequence of all of that advice was well you need to eat all of this protein really fast and you've got this really high number so you know start taking this protein supplement straight afterwards which I did for a number of years now I really worry about it because I look at it and I see that like Zoe says this is a high risk processed food I gave that up as I started to understand in the last few years like all these issues around processed foods, but obviously it gives you a lot of protein. What are your thoughts on that, Stuart?
Starting point is 01:01:14 So pros and cons. The pros of a protein supplement, it's just protein. If it's protein powder and you don't have, you know, a lot of people are like, well, I don't want fat, I don't want carbs because, you know, they're going to kill you and et cetera. So, yeah, I'm being trained, but you get my point. And maybe there's a time and a place for that.
Starting point is 01:01:32 It's convenient. And when I deal with a lot of athletes who are in sort of different places, they can't they don't have access to the foods that they would normally eat so i'm like check outside of that it's really hard to think of too many pros uh the cons are as you point out it's processed it's stripped of other nutrients i mean i love your pyramid i mean the other part is is we put the big umbrella over the top and i'm like it's pretty delicious too right like you know i mean i think that we've lost a little bit of sight of um food is an enjoyable commodity that we spend, you know, our time cooking and eating and with friends sometimes, and we focus on
Starting point is 01:02:12 nutrition and it's ingredients, but we all eat food. And I think maybe we've lost sight of some of the enjoyment that comes with eating food. So from that standpoint, when you look at some of the bars that are out there and you look at their contents and you look at the amount of sugar that it's in them, the amount of sodium that's in them, I'm okay with those if you think that that's, you know, a snack. But, you know, just let's be clear that it's not a free pass and it's not, you know, a lot of people say, oh, it's healthier than a chocolate bar. And I'm like, well, if there's the chocolate bar, this is how much healthier the protein bar is. It might be a small nudge, but it's not like, you know, this is a free pass and this is super healthy. And, you know,
Starting point is 01:02:55 hopefully we've made the point clear that that window and everything else is sort of overhyped in terms of its importance. And I know it's boring, but a food first approach is going to serve you a whole lot better than any form of supplement will. I work with athletes, and I will say is that they go to supplements, and the number one reason for it is convenience. If you're having like a weight protein isolate or a soy protein isolate added to your smoothie that you're making yourself, there's less risk. But a lot of these supplements are high-risk foods. So if you have a Snickers bar. It's a high-risk candy bar. If you add protein to it, it's a Snickers bar with protein, but it's still a Snickers bar, right? Like, it's not actually a good source of protein.
Starting point is 01:03:40 The data is also really clear that the more of these foods, these high-risk processed foods you have, the more you're decreasing your chances of living a long and healthy life. So the study I love, the test here at our study in nature, they calculated that ultra-processed food and high-risk food consumption gives you a 32% lower odds of healthy aging. So when we think about protein supplementation, are you just adding weight protein isolate because you're an athlete? Or are you eating protein cookies? If it's B, if it's the protein cookies or protein Snickers bar, you're actually possibly actively reducing your healthy life years. It's not a good idea. So protein supplements, I think is too broad a term nowadays. It's gone from being genuinely just added isolated
Starting point is 01:04:20 protein to junk food that has got a protein health halo sprinkled on top. And that to me is just a no. I mean, the thing that I'm struck at the end of this is once again, there's been a big role of big food companies into this story, right? Because you've talked about these individual foods has been really bad. And both of you are like very aligned on that. But it's not just like randomly happened that you get the Snickers bar that says, you know, high in protein or the ice cream or any of these.
Starting point is 01:04:51 And I think they play incredibly strongly to why there are so many listeners who contact us and ask because people see this all over the supermarket. They're like, oh, wow, I must be short of protein. And also, oh, so if I get the thing that's high in protein, that actually means that this food, whatever it is, is going to be good for me. And it's incredibly cynical. And there's usually a markup. People will pay 20% more for the same product with added protein.
Starting point is 01:05:18 great, great moneymaker because way protein isolate is super cheap so you add that to your waffles, frozen waffles and you're suddenly selling them for more money and making more money in the process. It's a complete marketing play unfortunately and it's not serving people's health
Starting point is 01:05:33 it's just serving profit margins at the moment. Final questions, we've gone through lots and lots of advice. If I was going to ask you to speak to the listener and just give one, simple, actionable tip that they could take away right now that would start to make a change, to make them healthier, what would it be? Does it have to be nutrition related?
Starting point is 01:05:59 No, no, it doesn't. Then exercise, it seems trite, but after years of doing this and essentially believing, thinking based on data that protein was more important than it was, you know, I've come to the realization that it's the exercise. that really drives the bus, and protein is a small part of the benefit that could accrue from doing the exercise, and that doesn't matter whether you're a runner or a lifter or anything. That's far more important than getting more protein in your diet, and enjoy food. I just think that we've obsessed around ingredients for too long, and we've lost the sight of a little bit of what it means to sit down.
Starting point is 01:06:48 and, you know, make and then eat a good meal, whether it's by ourselves. I know it's not always motivating, having lived alone to cook for yourself, but particularly with other people, beginning to the older I get, I think, you know, meals with friends, those are special times and should be cherished for sure. I would love people to start thinking about how they can replace some of the protein they're getting from animal foods, like processed meats, red meats, or, to your point, Jonathan's snack foods like protein supplement cookies to healthier plant-based proteins that we know are going to improve longevity and outcomes in the long term. So how can you integrate more lentils,
Starting point is 01:07:27 more beans? Can you try tofu or tempe? Try different oily fish. Like add macrol to your shopping list, add some anchovies, some tin sardines, and just really see how you can integrate these healthy proteins into your everyday life and get rid of some of the ones that are like you to be doing more harm than good. I'm going to try and do a summary, at least of the key things that we covered. I think my starting point is the recommended daily protein intake, which is sort of 0.8 grams per kilogram, is too low. And so that is really interesting. The second big thing I'm taking away is you have to lift something heavy to get any benefit from protein. So if you're listening to this and you're not lifting anything heavy,
Starting point is 01:08:08 don't get tricked into all of these products saying eat more protein because it's not relevant. The question is, what could you do to lift something heavy in order to use it? The next thing in my mind, and Federica, I know you've been doing a lot of work on this is like the right amount of protein for you is personalized. There isn't just one single number, and that's, I think, part of the reasons you're talking about, you know, this recommended daily intake being too low. So you're saying, you know, for regular healthy adult, it might be like one to one point two, so it's like a bit higher than the number that we've described.
Starting point is 01:08:41 Yep. But in certain cases, and you're particularly talking about people as they're getting much older because it's harder to absorb this and it's so important to protect them, it might be higher. You know, when you're very young, you're describing like what you get in breast milk and it's a bit higher. But in no cases is it as high as we've been hearing a lot from sort of influences and indeed from the trainers if we go and see them. And so, you know, I think your own intake is really interesting. You say sort of 1.3 to 1.4 and you're obviously, you know, serious about wanting to protect your health. than going to the gym, if you're working out a lot and you're talking about this is the CrossFit, this is the power athlete, hardcore, the person who's like optimizing this at the very best is at 1.6. So again, like still well below the two. So even if you're aspiring to that, that's sort of 1.6. The big thing that you've changed your mind about is this idea that the only way you can sort of solve for your protein intake is eating lots and lots of meat. And that actually that's really a myth. And it turns out that plants are not deficient in amino acids, but you can't just eat one plant. So you've got to eat this sort of balanced diet. The timing is not a big concern.
Starting point is 01:09:53 So again, unless you are literally competing for your country, you don't need to worry about eating protein immediately after your workout, which again reduces some of this pressure, I think, to eat these protein shakes. Because if you're out and about, right, then you sort of have to do it immediately, but if you've got more time, then I think it comes into play. And then I think you talked about some really practical things, which I thought was really great. Like, you could think about breakfast where you're probably not eating a very healthy diet and you may not be getting very much protein. Greek-style yogurt, mixed with kefir, which I had not realized was particularly high in protein as well, but also like eggs, eggs and whole grain bread. That's a fantastic breakfast.
Starting point is 01:10:32 So breakfast being one of those things you could really change to improve both health and protein. and that in general, there are these obvious things we think about being protein like eggs and maybe oily fish and dairy, those are good, but actually there are all of these things like legumes and pulses as your chickpeas and lentils and beans that actually have lots of protein in. And I was worried you were going to tell me I wasn't getting enough protein, but actually I think it sounds like I'm going to be okay. Yeah, the odd part, again, about the complementation that we talked about, about the grain
Starting point is 01:11:03 and the legume or the bean, is these days. because in past times when people had to do that, the legumes were the rate-limiting thing. They were hard to find. Now we can get them almost everywhere. And there's a variety of different sources. It used to be it was two different types of beans and there were peas.
Starting point is 01:11:24 Now it's all kinds of things. So I think that that's an important point. The pairing with the grain, it might be tasty. It's actually not necessary if you eat enough legumes. But it makes a great base for any meal. If you have a legume and a grain, you know, quinoa, peas, beans and barley, spelt and lentils. It's just instant pairing. If we could take the protein out of quinoa, it has the same protein quality score as milk.
Starting point is 01:11:54 Huh. Yeah, there you go. Amazing. I'll end this episode with something I think you'll like, a free Zoe gut health guide. If you're a regular listener, you know, just how. important it is to take care of your gut. Your gut microbiome is the gateway to better health, better sleep, energy and mood. The list just goes on. But many of us aren't sure how to best support our gut. I wasn't sure before doing Zoe, which is why we've developed an easy-to-follow
Starting point is 01:12:24 gut health guide. It's completely free and offers five simple steps to improve your gut health. You'll get tips from Professor Tim Specter, Zoe's scientific co-founder and one of the world's most cited scientists, plus recipes and shopping lists straight to your inbox. We'll also send you ongoing gut health and nutrition insights, including how Zoe can help. To get your free Zoe gut health guide, head on over to zoey.com slash gut guide. Thanks for tuning in and see you next time.

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