Dr. Mario Alonso Puig - Tu intestino influye en tu estado de ánimo: microbiota, ansiedad y cerebro

Episode Date: April 25, 2025

En esta conversación junto a Alberto en COPE, exploramos la importancia del tubo digestivo, un segundo cerebro que conversa a diario con el que llevamos en la cabeza.Explicamos por qué un gran porcentaje de nuestro sistema inmune vive pegado a la pared intestinal, cómo la microbiota regula hormonas y neurotransmisores que influyen en la ansiedad o la tristeza, y de qué manera un intestino permeable puede encender inflamación y alterar el estado de ánimo. Hablamos de bacterias aliadas, de la importancia real de la fibra, de los fermentados y los probióticos (especialmente cuando tomamos antibióticos) y de los riesgos de un consumo excesivo de azúcar, grasas saturadas o alcohol.También hablamos sobre la intuición “en las tripas”, y cómo pequeños gestos diarios pueden traducirse en mayor energía, claridad mental y equilibrio emocional.Mi deseo es que este vídeo te ayude a mirar tu alimentación (y tus síntomas) con otros ojos y te anime a cuidar de tu microbiota para sentirte, literalmente, mejor por dentro y por fuera.Ojalá este episodio te acompañe y pueda convertirse en una inspiración a la hora de despertar y florecer tu verdadero potencial.Página Web: ⁠⁠⁠https://marioalonsopuig.com/ ⁠⁠⁠Instagram: ⁠⁠⁠https://www.instagram.com/marioalonsopuig/⁠⁠⁠ Youtube: ⁠⁠⁠https://www.youtube.com/@MarioAlonsoPuigOficial⁠⁠⁠ Facebook: ⁠⁠⁠https://www.facebook.com/MarioAlonsoPuigOficial⁠⁠⁠ Entradas a la nueva conferencia 2025: ⁠⁠⁠https://marioalonsopuig.com/gira-2025/

What we eat is affect to our form of being. What we are our essence and that is something that not depends

neither what we think we're, nor what we we're doing, but our form of being, our personality is a person's

is a fact directly for what we have been with depression clinical that have been years in

treatment with antidepressives that were with changes in the nutrition and in six months

were much more. This is a podcast for all those people who want to think in grand, and feel in great and live in great. I'm the doctor,

Mario Alonso Puch, I'm going to be to make this adventure of discovery and the discovery and I'm going to maybe I'm but we're

we're going to get us much more much more very much more good days. Good days. What you're going to do you?

know? No. And what you've got you? Do you know? I'm Well,

I'll say I'm sorry I'm going to have eaten I've done a sumo special with cale with arandanos

with a middle platano is what I'm It's good Alask Goods Goodsame Goodsame

Goodsame Soles have Dolores of Barriga? No Is that I'm

I'm I've got I've got I've got I sometimes problem with and what I'm fundamentally the

seminars in those I'm not, there's some there's a time I'm like, I'm going to this luxury because at the

final I think that will be with the dopamine, no, to get what you want to you want to

make you more well, I'm doing the time but then you eat the hambhers, you know,

you're you're saying, and what I'm saying that that's that I'm that I'm

when they've got to when I'm not for the fact of that I've been more that I'm that I'm more

Triste, that I'm distinct. Effectively, you see very well the distinction, no. The part of the

ardures, what's the name is the reflux gastroesophagic. It's that we're a very,

very precise, in what he does it doesn't go to the stomach to the oesophage,

that the softado not not is a acid, it's a acid, a carosive, acco,

but a sometimes, well, the things that all we can pass, we're

a alteration in that spinter and it's up acid. The second part is different. The second part is the other part about the edge Cerebro-intestine, is that how really the tube digestive, as well

mostro clarissimely the doctor Gershom at the University of Columbia in New York, the tube digestive is a second Cerebro and is in permanent communication with the first

Cerebrough that we have in the cavity cranenian and they're interchambiating substances, are interchambing factors that

have an influence in our personality, our state of anim, and even in the development of many in many of the same thing. But what is a second-creas? For that you can't etiquette to an organ as a second-cerebrough,

the entry has to have a capacity of processment special. And in the case of the tub digestive, there a processment very sophisticated,

not only only in what is the movement of the animals and the absorption, which is a process complicated-sim, but in all what

has to be for example, with the regulation of the system of defense. The system of defense depends

fundamentally of the tub digestive. The question is why? Because, one is imagines

his soldiers for the body. Because the 80% of the regiment is

in the tub digestive. And the application is very simple. But

nothing obvious. The tube is the surface the surface.

For example, many people would say, An Alberto, that the surface more is

the skin. Well, the skin only are two meters quadrants of a

position. So, and the surface of the tube digestive,

if it would be the equivalent to two canches unites. What

you're What you? Sure. So, those those three hundred eight hundred

meters quadras I'm so. What? I mean that the major

part of the venenos, products toxic, agents dangerousos that

can enter in the body, not enter in a the blood, they're a through the digestive.

With what the 80% of our exercise of the system immune is there. What is the

system immune has a debility. The debility is that can overactuar.

And if overactua produces a inflammation in different parts of the

body and in the cerebr. That does in the brain in the Cerebrough. This inflammation does a place to quad of anxiety and of depression.

Cere, I mean, nobody would have imagined that detractor of a quad of anxiety or depression could have a bad alimentation. Today is incquestionable. For that you take us an idea, there's a substance that's called LPS, it has the

Parenthood, the bacteria, and it's like what most fear can give to the system immune, that enter LPS. Because LPS, because LPS, that is a lipopolisacarid, the part of the cellular of the bacteria,

have a potential toxic brutal. Fifate, imagineate that there's a gram of LPS in the interior of

digestive because there are that they're but not have entered in the blood. One million.

With what they enter? 100, so, in bed of one million, 100, 100,

100, 100, 100, 100, 100, 100, 100, yeah,

so it's produce a reaction inflammatory tremendous. Just for 100 when the normal in your digestive is that there's a million. So it has to be a barrier ultra-exquisita in what is the pari-intestinal

as in that system defense, for that that's what you do you can't, that when a lot of a intestino permeable, a mal-functioning

of the intestino that has to be with a mal-functioning of the microbiota, the bacteria that have been there, the virus and the hongos, in

that moment, the reaction inflammatory you can generate that a quadra of anxiety, a quadra of depression. When if one would be cared to better

to the tub digestive, many problems of anxiety and depression will resolve. I have a little and at the most he's got to the issue of

the issue. But as you, they're profoundly connected. The intestine, the apparatus digestive, with the

brain, we're going to have some that we're a lot of, but that's a sensation of emotion

before to see a person, or that sensation of nausea that's people,

before to confront us a problem or a, or a, a, it's a very much to be.

And in English, in English, I feel in the guts. I'm in the tripas.

So, then it's not so it really well, where it is that is that's a nerve,

he's called the nerve vago, and the structure structures important times of the brain percent of the fibers of the nervio vago, no mandan information of the Cerebro to digestive,

but that's the tube digestive to be the tube digestive to the Cerebr. The tube digestive is, the tube digestive, is that not know we know how it can't, let us know the intuition

somatic, the intuition of the body, and he's a information to the Cerebr. In the Cerebrough there is a thing that's called

the Insula of Rail, insula, because it has form of Isla and Rail because was the discovered that is constantly in contact with this information and it's very much to be with what is the intuition the sensation of that something not has to be in a lot of

in a lot of it's a is a a it's a one is a a one thing is a clear I know that I'm I'm going to hear from here and I'm that he's the microbiota and that who can't hear that's it's that's that's that's actually that's to you that's I've tried a... I've tried

a fragment a little little bit a little that's a per year of that we're to all we're

not of the extraordinary complexity and beheal and the tube digestive for the this is the

part of the light is the part we're a and this is what we see we're

we're just we're these these are the bellosities intestinal is like like some

some things ruvos that are in the intastien so what what

these cells have to to avoid how it's that enter in the blood

what you need to enter in because if I enter a product toxic not only is that

it's the system of the defense that's that's to be to beckion to be

in mind many many many dysclerosis multiple lupus eritematos

disemines disseminated epititis autoimmune etc many many quadros

alergic even today quadros that never had never had

with a bit with the digestive, as the autism, it seems that they have a connection with the mal-functioninging of this barrier and the entry of products toxic, that for some-missos, they're that, also, hyper-activate

the system of defense, and then the damage collateral is that the substances that produce, not only only attack the products toxic, but they're attacking the own cells, let's say, let's the bombs that that they're that they're chinochina six

the interlequin a six, the interlequin a eight et cetera clear, also they're also they're but how we're doing

because what you're describing is what is the what is the what is the what is what protect the that's

that's a lot of there's a there's and all are you don't know well

this representary the nucleus to distinguish the no the nucleus the nucleus

the the cromatina so that so it's how we do it protect the one the microbiota is living in the

in the light in the part of and it's constantly in communication with the apparato digestive and

with a microbiota sana what he has is to eviter that this intestino

be a make that let's pass what no has for example

there a a a carmane a manse am mucin and fila that what

does is favor is to favorce the so that the cellisiformes That moco is a barrier spectacular.

When the acermansia begins to backer, the production of moco is minor, and it's more that penetra in the bacteria madas. What favorece, for example, the good functionament and the good cresiment of the carmansia? For example, a diet

rich in fibres, especially inulina. For example, the vinegar of manzana. The vinegar of manzana is very favorable for this type of bacteria. For example,

the tener ojo with the alcohol that's much ojo with the stress chronical because the stress chronical is the stress maintaining the time

altering profoundly the microbiota what occurs when these bacteria good like the Kermansia or the

lactobacilos start to get to get the bacteria malas because he was thinking microbiota

and it's me has been to the about probiotics like the has been something to

have some has to have to distinguish what they're what they're probiotics probiotics,

probiotic and psychobiotic is a fibrotic is a fiber that could serve to

eat a bacteria that we have the tub digestive those bacteria

with that we're not we're not only they're they're they're

they're they're they probiotic are the bacterias in

si and you now a message yeah that I'm the opportunity to be in this space

every person that's he has to come with probiotics because the antibiotics are necessary

in many cases but not only only the bacteria malas but they're

in some bacteria good so there's there are to adder probiotics because

that a other so so that what are the psychobiotics

those probioticos that have a level psychological. Where do where are the probiotic? Well,

in any it's a very easy to find out of the pharmacies in the places of herbolaries.

It's a and for you know, in the yogurres very important. The fermentatos.

The food fermented are very interesting for the microbiot are. They're

are good are very very for because they have they're they're

so put so And put it there for that it's a very much because while you're the image

on the last time everything all the entire we're doing the same microbiota very very good

question well and that's one of the great problems we know we're we're not we're

we're the 90% of the genes what is that one is on those

not in others in other populations very speciales we're we're just the

of the genes of the genes of the microbiota. There's a lot of there's a great diversity.

Now, the grand problem that we've seen in the city is the fault of diversity of the microbiota.

Poplations that are in places, for example, in the certain deserts of Africa or

Australia, that have studied and that have been products much more natural. It has a

one, a microbiota much more diverse and the diversity of the microbiota is very

necessary. Because I have heard to say various times that we're going to we're going to I think

I think I think we're more than what we're going to now what we're what we we're

if it affects to our form of well it can be the malinterpreted to that's

that's that's what we we're our essence and that is something that is

something that doesn't what we we think we we're we're not we're not the

thing our personality our personality is if is affected directly for what we're how it's possible that someone

that's not seen never a or why when when you start to keep you to eat and there's a

form of there's many there are many many types of dietas but how how much

how long time you when you're to get to get you not for eating but for what

is what you're going to what is going to not physically, but psychologically, well, it depends much of the

level of that's a person. We get into that the person, is something that's extraordinarily

complex, sophisticated, and effective, that in when you're doing to doxicity, it's put

in march to get a but, but, it depends also of the level of

that you have come that you all the maybe you're completely of it.

What First, it implic a reduce the toxicity. In second, dar to the organism the opportunity to eliminate the toxicity existent. And in third, you're going to give those things that

need to function to correctly. Because me said before, that's straightly related to cases of autism, including, of anxiety and depression with the state of the microbiota,

and me said that there are studies that they're now right now, of combat for example,

the anxiety and the depression with nutrition. How is it? Well, we're unfortunately

in Spain we're one of the best diet of the world. There's the Mitterran

and there's also the diet atlantic that's a diet very good and then really what

we have is understand that the microbiota for functionar well, necessarily

vegetables, vegetalels multicolores that also are interesting those the neces

and that we to have to have ojo with the sugar and we have to have to have eye with the gases because the

problem many times Alberto is that in these populations that in Africa or in Australia that's studied

in either have studied to study the the consumer of fibrous in those approximately

about 50 grams at day and in the society modern is rare that we get us

to the 15 grams so all so So if a person, the 70% of what is vegetal, not is that you have to take only vegetables in absolute. And procura

that are they're going to begetalists of good quality, that's it's it. That's it, that are they're going to, for that not, for that don't have components of toxicity. And and it's a little bit of this and reduce their consumption of sugar and reduce their consumption of gas saturated.

In general, it will be better and, sure, that it will be to note. There are people, for example, with depression clinical, that have been years in in treatment with antidepressives, we're talking

of years, in the treatment with antidepressives, that started with changes in the nutrition, and in six months it's

much better. It's a, and, and when you've been a period, in those that I've cuted much,

and it's I think, I think it's not, it's not a question, it is to have a correct

alimentation, because when we're doing that we're doing, that this, that's exceptional and

it's not absolutely of course I'm sure the language for us it's actually affect directly

to the perception not we we're in account that the major part of the

the health the most of they're they're they're they're

they're one of the origines the tub digestive that is the incredible

importance of the tub digestive who who would imagine

that quadros of hypertension arterial that pathologies autoimmunes, that quadros of

allergy, or that even the autism or the disease of Alzheimer could have some kind of with the function of the immacquated to the digestive.

Today is something that really is a really relevant. One one last question that has

been very scatological, but I think is opportune. Expulsed much gases

you say that your intestine not is a good? The production

of much gas indicates that there something that something that's what is

the blooding the the distension abdominal what are the don't

those don't in Europe there are 80 million of people 80

million with colon with an colonel irritable all

these all these in the transit or the person that

has a person that that it has a a tracito a bit of a time they're a

un-just of the microbiota for the sure that's well then the cali you know so then

to cut them because there many people no no no no no no the most important is the most

important is the fiber the the oldivable is a element of tremendous

of importance because we're we're not a organo that is the microbiota that without

not a organ internal function have been in mind that the microbiota produce

around of a million of molecules and they're controlling

montones of processes from how function our system

endocrine how functioned our practical how operate how

operate the we're we're we're talking a change

It's a fortunate that we recognize this for that we know that we're what is the nutrition. And we can't say with an enormous orgue because

Spain has the the best cociners of the world. Probably I'd say that the bestoration that is

today. So we can celebrate it and more that we have a diet that fundamentally be a

diet that a good that's you have liked and could to become a inspiration at the hour of to display and to make flource your

verdadder potential.