Feel Better, Live More with Dr Rangan Chatterjee - #147 How To Improve Your Sleep and Why You Should with Professor Matthew Walker

Episode Date: January 13, 2021

Improving the quality of our sleep is arguably the single most effective thing that we can do to reset our brains and recharge our bodies, yet many of us just aren’t getting enough. But what is the ...optimal amount of sleep and what can we do if we struggle to get enough? I’m delighted to welcome back onto the podcast the world-leading sleep researcher, Professor Matthew Walker to answer these questions and more. Matthew is author of the international best-selling book ‘Why We Sleep’, Professor of Neuroscience and Psychology at the University of California and a fountain of knowledge when it comes to all things sleep. My last conversation with Matthew back on episode 70 of the podcast was one of the most popular to date. A few months ago, I asked my podcast listeners to let me know what further questions they would like Matthew to answer and in this conversation, I put some of those questions to him. We cover how many of us feel that we don’t have enough time to sleep for 7-9 hours but how rather than stealing time from us, getting more sleep can actually make us more productive. And even grabbing an extra 15 minutes of sleep a day will have benefits for our overall healthspan. Matthew shares some brilliant tips on how we can regain control of our sleep and for those who are really struggling, he explains that there is an alternative to sleeping pills that is just as effective in the short term, but much more effective long term. We cover so much ground in this conversation, including polyphasic sleep (sleeping for periods of time throughout the day), unbroken sleep and why lying awake in bed for long periods of time can affect our ability to sleep in the future. Matthew shares the fascinating and dramatic changes that have occurred in the way we sleep and dream following the coronavirus pandemic and why it has allowed what he calls “the revenge of the night owls.” We delve into REM sleep and how it is one of the best forms of therapy – the brain can literally re-wire negative memories when we sleep. Finally, we cover sleep trackers, caffeine and how sleep impacts our immunity. This really is a fascinating conversation, full of fresh insights and actionable tips that we can all put into practice today. I hope you enjoy listening. Show notes available at drchatterjee.com/147 Follow me on instagram.com/drchatterjee/ Follow me on facebook.com/DrChatterjee/ Follow me on twitter.com/drchatterjeeuk DISCLAIMER: The content in the podcast and on this webpage is not intended to constitute or be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. 

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Starting point is 00:00:00 Sleep is the single most effective thing that you can do to reset your brain and body health each and every day. Sleep is, on the basis of all of the scientific evidence, it is the elixir of life. It is the Swiss army knife of health. And if you use this sweet spot of seven to nine hours, there's a very simple truth, which is that the shorter your sleep, the shorter your life. Short sleep predicts all-cause mortality. Hi, my name is Rangan Chatterjee. Welcome to Feel Better, Live More. Hello, I hope you are all doing well. Today's episode is all about one of the most important pillars of health, our sleep. Now, improving the quality of our sleep is arguably the single most effective
Starting point is 00:00:52 thing that we can do to reset our brains and recharge our bodies. Yet many of us simply are not getting enough. Now, when we talk about sleep, we need to be thinking about the length of our sleep, but also the quality. In today's episode, I am delighted to welcome back the world-leading sleep researcher, Professor Matthew Walker. Now, Matthew is author of the international bestseller, Why We Sleep. And he's professor of neuroscience and psychology at the University of California. And he is a fountain of knowledge when it comes to all things sleep. Now, long-time listeners will know that this is Matthew's second appearance on my podcast. My last conversation with him back on episode 70 is still one of the most downloaded and shared episodes to date.
Starting point is 00:01:42 If you have not heard it yet, I would strongly advise that you go back and have a listen after you've heard today's show. There are so many golden nuggets in that first conversation. Now, today's conversation with Matthew moves into areas that we did not cover last time. You may recall that a few months back, I asked my podcast listeners to let me know what further questions they would ideally like me to put to Matthew on a future podcast. And the response was phenomenal. So many questions you had for Matthew. And in today's episode, I put those questions to him. Unfortunately, it was impossible to get through every question, but I have tried my best to cover as many as possible. We cover how grabbing an extra 15 minutes of sleep a day will have benefits for our overall
Starting point is 00:02:31 health span. We cover polyphasic sleep, unbroken sleep, and why lying awake in bed for long periods of time can affect our ability to sleep in the future. Matthew also shares some fascinating and dramatic changes that have occurred in the way we sleep and dream following the coronavirus pandemic, and why it's allowed what Matthew calls the revenge of the night owls. We also delve into a type of sleep called REM sleep and how it is one of the best forms of therapy. Our brains can literally rewire negative memories when we sleep. And finally, we cover sleep trackers, caffeine, and how sleep impacts our immunity. This really is a fascinating conversation full of fresh insights and actionable tips that we can all put into practice immediately. I hope you enjoy listening.
Starting point is 00:03:26 Now, on to my conversation with the one and only Professor Matthew Walker. Yeah, I remember really well our last conversation in the bowels of Penguin a few years ago now. well our last conversation in the bowels of penguin a few years ago now yeah we were um it was in the um sort of the sub-basement walk down um i think it's it's at the level where usually sort of nuclear bunker operations happen but we were deep in the bowels of a penguin random house but it was a very special time um i love that time with you and just felt like speaking with a remarkably insightful, intelligent friend who I just could resonate with. And he was empathetic, empathic. It was great. Yeah, me too, man.
Starting point is 00:04:16 I really remember it. Remember it very, very well. And, you know, we both just had our books out at the time, our first books. You know, we both just had our books out at the time, our first books. And on that, your first book has become a global juggernaut of a book. And with good reason. It's jam-packed full of information. For people who are listening to this and coming across you for the first time, I would highly encourage you to check out Matt's book, Why We Sleep,
Starting point is 00:04:46 and also check out the first conversation I did with you because it is full of facts, full of all kinds of insightful information about sleep. But I thought where we might start, for people who've not heard that conversation, you said in that conversation that sleep needs a better PR job on it, right? We need better PR on sleep. And so I thought maybe the place to start would be, why should we care about sleep? Well, you're right. I think sleep is the neglected stepsister in the health conversation of today. And it remains so so unfortunately. Why should we care? We should care because sleep is the single most effective thing that you can do to reset your brain and body health
Starting point is 00:05:33 each and every day. Sleep is on the basis of all of the scientific evidence. It is the elixir of life. It is the Swiss army knife of health. And I think the decimation of sleep throughout industrialized nations is having a very clear and significant impact on our health and our wellness. In fact, just to sort of give it in the most blunt terms, if you use this sweet spot of seven to nine hours, which we'll come on to, there's a very simple truth, which is that the shorter your sleep, the shorter your life.
Starting point is 00:06:09 Short sleep predicts all cause mortality. But to me, I think, Rangan, what's more important is that investing in sleep, and it really should, most people right now think of sleep as a cost. You know, how can I sleep less? Because I sort of want to be awake more and do more. And I see sleep as the opposite. I see sleep as an investment. And it's an investment, not just in your lifespan, but it's an investment in something you care about so critically, and I do, which is your health span. It's not just your lifespan. critically and I do, which is your health span. It's not just your lifespan. And both of those sleep, you know, sleep is almost like the tide that raises all of the health boats. And I think it's wonderful that people think about these individual silos of health,
Starting point is 00:06:58 your cardiovascular health, your metabolic health, your mental health. But what's remarkable is that you can sort of, you know, focus on each one of those separately if you want. But there is this Archimedes lever. There is this one thing that if you improve it, all of the other health boats rise on that singular tide of sufficient sleep. That's why I think we should care about it and care about it very passionately. How much are you sleeping these days? So I could pull out my phone and look at my aura ring. I think last night it was seven hours and 58 minutes,
Starting point is 00:07:40 but I was in bed for eight hours and 35 minutes. And I think this is a really important point. Let's not focus about the duration right now. People often hear folks like me say, okay, how much sleep do we need? And the response is somewhere between seven to nine hours of sleep a night. That's what seems to maintain health.
Starting point is 00:08:05 Once you get below seven hours, we can measure objective impairments in your brain and your body. But then people think, well, seven hours of sleep, so I'm okay to go to bed at 11 and wake up at six. That's actually not true. Because for you to get seven hours of sleep, you normally have to be in bed for at least eight hours. And the reason is something called sleep efficiency. So let's say that I'm in bed for eight hours. If my sleep efficiency is 100%, which is completely abnormal, that would mean that for all of that time I'm in bed, I'm asleep. Now, if you're healthy
Starting point is 00:08:48 and you're sort of not sleep deprived, you will have a sleep efficiency of somewhere between 85 to 95%. So 85% is our cutoff for good sleep in terms of sleep efficiency, 85%. So if you're healthy and you've got a good sleep efficiency of 85%, to get a minimum of seven hours of sleep, if you do the calculation, you'll need to be in bed somewhere close to eight hours and 13 minutes. So I think one of the other essential parts of this is sleep, what I call sleep opportunity. You need to give yourself the right opportunity to then get the appropriate amount, the appropriate duration. So when I say seven hours is the minimum, please don't think that that's seven hours
Starting point is 00:09:40 of opportunity time. It's going to be much closer to eight hours to get that minimum of seven hours. Does that help, Rangan? Yeah, yeah, yeah. Really, really useful. And I think making that point right at the start of our conversation is so useful, Matt, because people want to squeeze it in and go, they might be starting to prioritise it and go, I need to get seven hours. But they'll often think about that seven hours from entering the bedroom and leaving it in the morning but you beautifully explaining why that's not the case and matt the format for today was going to be um a bit different from last time there was
Starting point is 00:10:18 so much interest in our conversation last time i think it is still still the top or in the top two of all of my episodes ever in terms of how many times I've been listened to. And I think that's because of a, the content, but also the clear manner in which you deliver it. But there's a huge interest in sleep. And so we went out to my audience for some questions that they wanted answering from you. And I've compiled a lot of them in a document. There was a lot of similarity. And I thought what we might do today is just go through a lot of the questions that my listeners really would like answered if possible. Is that going to be okay with you? Lovely. Yeah, that sounds great. Fingers on buzzers, no conferring. Questions
Starting point is 00:11:02 start at 10. Exactly. And this one, that's not the first question, but I think it comes in here really nicely. Someone's actually said about length of sleep. I think it's totally unrealistic to get seven to nine hours sleep a night unless you are a teenager. Okay. So that's interesting that someone feels that it's unrealistic for them. And the follow-up question was, is it okay to sleep for three hours, be awake for an hour and have three more? So there's a general point here about whether our sleep should be unbroken or whether it can be polyphasic. Yeah, I'll take the first question. I think it's so understandable when people are struggling with sleep and they're having sleep difficulties, or the,
Starting point is 00:11:46 and I don't know which of these two it is for this person, but, or it's the fact that life just doesn't seem as though it will allow or permit you the absolute human civil right, which is getting sufficient sleep. But I think just to come onto the first part of that, if you are someone who is struggling with sleep, and I would stop focusing on this idea of the seven to nine hours, that's only going to make matters worse. of the seven to nine hours, that's only going to make matters worse. Start with incremental changes and firstly ask yourself, why is it that you don't feel as though you are capable of getting that amount of sleep?
Starting point is 00:12:35 Let's set aside the idea that it's just your schedule that prevents that. Let's come back to it being something that's biological. The first thing I would say is, please go and see your doctor and ask about help with sleep. My suspicion is that it could be something along the lines of insomnia,
Starting point is 00:12:54 where you're not able to either fall asleep or you can fall asleep, but you can't stay asleep. You don't have to look to medication. I think this is one of the big fallacies that we have in medicine with sleep right now, where we're medicating people with sort of classic sedative sleep medication. There is an alternative that is just as effective as sleeping pills in the short term, but is much more effective long term. And it doesn't come with the harmful side effects
Starting point is 00:13:25 of sleeping pills. And that is something called Cognitive Behavioral Therapy for Insomnia or CBTI. And if you just go onto the NHS website and you search for CBTI or you search for insomnia, you'll get some great information. That type of therapy will start to help you regain your confidence in the statement that seven to nine hours actually is possible. You know, unless
Starting point is 00:13:58 you're starting to move into your later life stages, where sleep becomes difficult, up to ages 50 or even 60, getting seven to nine hours of sleep a night should not be impossible. It is certainly a possibility. But when you are struggling with insomnia, you lose confidence in your sleep and then you can come up with statements
Starting point is 00:14:24 such as the one that we just read out there. And insomnia is a situation where you worry that your sleep controls you. But when you go through CBTI, gradually you control your sleep. In other words, you regain confidence in your ability that when you walk into your bedroom and you tuck yourself in at night, there is a consistent solid seven plus hours of sleep
Starting point is 00:14:52 awaiting you. And it is there for most people. So I would just sort of put a sticky on that and say, please don't despair. I understand if you're struggling with sleep, why my words of saying seven to nine hours of sleep is just fine would feel like an impossibility or even an assault on your belief in your ability to generate sleep. But honestly, for most people, that capability is very much present inside of you. Yeah. I mean, thanks for that. That's very, very helpful. I'm just wondering, one could interpret that question another way. And obviously, we don't know how the person meant it, but it could also be that I don't feel I have enough time in my life for seven to nine hours sleep. I'm too busy. If that was the way they meant it, how would you frame it for them?
Starting point is 00:15:44 busy. If that was the way they meant it, how would you frame it for them? I think there's a number of ways that you can do it. The first is practical. The second is contextual and belief mental. Belief mental, contextual, what I mean by this is saying many of us think of sleep like a cost. And so you're working away at night and you think, well, you know, I don't want to waste my time going to bed right now. That's going to come at a cost of me because I could do an extra hour of work. I think of sleep in exactly the opposite based on the weight of the evidence. If I get to bed tonight at the right time, it is an investment in my productivity tomorrow. It's not a cost to my productivity today. Because what we know is that when you are underslept, your efficiency in terms
Starting point is 00:16:36 of getting done what you need to get done is utterly miserable. Less sleep does not equal more productivity. That was not true in the rote industrial era, and it's never been more true now in the digital knowledge era. And so that evidence we can dispel in terms of a myth. You know, I think of it a little bit like, you know, boiling water on a stove. You know, why would you boil that sort of pot of water on medium heat when you could do it in half the time on high? And that's exactly what happens when you are getting sufficient sleep. The next part of that question, there may not be about your belief system. Maybe you do believe that sleep is an investment and it's great and it helps with productivity, but your day is just such that you
Starting point is 00:17:25 can't manage that amount. I would then really start to take a step back and say, but honestly, is that true? And think about what you want in life. What do you really want? And with concrete details, do you want to live a life that is going to be filled with health and is not inviting disease and sickness into your body or your brain? And if those are goals that you have, which I think for most people are, then coming to terms with the reality that we just have to find the right amount of time. You know, I think increasingly people are finding the right amount of time to exercise and they're also finding the ability to purchase food that is of better quality and make food that is of higher quality. And I think we need to take the same mentality approach to
Starting point is 00:18:21 sleep. The final thing I would say is practically, okay, how can you help me even just get a little bit more sleep in terms of opportunity time? I think there are several tricks and I'll just give you two of them. Often we have a wake up alarm. We set an alarm to wake up in the morning. Very few of us have a to bed alarm. Why not? And so set your alarm that would give you an eight hour sleep opportunity. Now you're probably going to ignore it. You're probably going to, and give your ability to have a snooze button on that too. So you can say, okay, I'm going to watch five more minutes of Netflix and you snooze again. But that persistent nagging of the notification will probably get you into bed a little bit earlier. The second thing is this,
Starting point is 00:19:11 in the, at least an hour before you are planning to go to bed, get changed into whatever you're going to wear for bed, get changed into your sort of your pajamas, your bed clothes, and then brush your teeth, you know, take your makeup off, floss your teeth, do everything, wash your face, do everything that you would normally do just before you go to bed, but an hour before, so that when that to bed alarm goes off, you don't have this 15 or 20 minutes of, okay, I need to sort of now go into the bathroom, do all of these things. And instantly you will add 15 minutes of time to your sleep opportunity. That's like compounding interest on a loan. 15 minutes every night, every week, every month is non-trivial. So that's a very long-winded answer, but I think changing your mindset and then with some
Starting point is 00:20:06 tricks and habits, I don't like the word hacks, but hopefully that can try to help with a difficult schedule. Yeah. I mean, that's absolutely brilliant. And I think what's really encouraging in terms of what you said there, Matt, is that you don't have to be black or white about this. Wherever you currently are, assuming you're currently underslept, you're saying that even 15 minutes extra a day is going to have a difference on your health and wellbeing. And I think that's very powerful. It really can. If we look at the evidence, there was some fascinating data recently on the importance of REM sleep for lifespan. And what they found was that for, I think it was something like for every five or 10 minutes, or maybe it was 15 minutes of
Starting point is 00:21:01 a reduction or a loss of REM sleep, there was a 13% relative increased risk of premature death. And so, you know, we don't have to, I like a guy called, who I think you've had on your show, maybe BJ Fogg, who's at Stanford. Yeah, I know BJ well, good friend of mine. He's lovely, does some great work. And he sort of, you know, thinks very much about sort of practical behavioral change for human beings. And a great example of this is getting people to start flossing their teeth. And you say, tonight, you have to floss your teeth. And it feels like a Herculean task if you're not really someone who does that. And sort of his ethos would be, okay, tonight, all I want you to
Starting point is 00:21:47 do is floss your front two teeth and you cannot floss anymore. Just your front two teeth. That's it. And do that for a week. And you are not allowed to do any more than that. And then gradually floss two more teeth in addition. And it just becomes more of a manageable task. And I think it's the same way with sleep. You know, don't say, oh, I need to add now an hour and, you know, 20 minutes to sleep because I had Matt Walker going on about something. Just try 15 minutes, you know, and even if you can get to bed 15 minutes earlier, then set your wake-up alarm five minutes later. And that way you've already gained 20 minutes. And in truth, your life won't feel that much different, but yet you've given sleep 20 extra minutes back
Starting point is 00:22:41 in terms of its longevity and healthspan boost. Yeah. And you think about that, not just in terms of 20 minutes in one day, that's 140 minutes in a week. That's thousands of minutes in a year. It's like compound interest in the bank, isn't it? It's just going to keep plugging away and growing and growing and growing. So yeah, really, really inspiring answers there. The point about unbroken sleep and polyphasic sleep. Yeah. So one of, I think, the really powerful emerging sets of data that we've had in sleep science over the past five years is the understanding that it's not just about the quantity of your sleep, which is what we've been talking about. It's also the quality of your sleep. And when I say quality, I mean both at a macro level in terms of how consolidated or consistent
Starting point is 00:23:39 your sleep is versus how fragmented or broken your sleep is. That's one way that we describe sleep quality. Another way that we describe sleep quality is the electrical quality of your sleep, meaning the depth of the electrical brainwaves that you're having, the deeper that electrical brainwave activity, the better the quality of that deep sleep. And what we've discovered is that a reduction in the quality of your sleep on both of those counts can be as, if not more detrimental than a reduction in the quantity of your sleep. Now, to be clear, both of them are necessary. You can't just sleep for five hours and have great quality sleep and expect that to be okay. But nor can you have eight hours of sleep that is very poor quality
Starting point is 00:24:32 and expect to be okay. And what we're describing here is if you are, let's say if you're someone who, you know, wakes up for 15 minutes and then you fall back asleep. And then, you know, another moment it's 10 minutes and you fall back asleep. And maybe you have, you know, two or three of those types of awakenings during the night. Don't worry. That's, that's normal. That's perfectly okay. Some people won't have that, but some people will. And that's, that's okay. That builds into what we spoke about at the top of the conversation, which is sleep efficiency. That we'll spend a fair amount of the night, about 10, 5, 15% awake, and that's part of it. But having a long stretch of time awake, such as an hour, is not really healthy. It's not really beneficial. And it's also not really natural. Part of the reason
Starting point is 00:25:26 people think it is natural is because of a practice that emerged. It seemed to emerge during that sort of Dickensian era, which was something called first sleep and second sleep. And if you look at this historical writing, it's very clear that this was happening. People would sleep for three or four hours, then they would wake up and then they would make food, they would play music, they would write, they would make love, they would socialize, and then they would go back and have another three or four hours. So it was two sleeps. But there's nothing really, with the exception of one study that people typically cite, there is nothing in our biology, our biological rhythms, that suggests that that's how we should be sleeping at night. But I'll come back to two phases of sleep in just a second.
Starting point is 00:26:14 So staying awake for an hour or so at night and certainly lying in bed for longer than 25 minutes is a bad idea. And here's why. If you are lying in bed awake, your brain starts to learn the association that this thing called the bed and this place called the bedroom is the place where I'm awake. And your brain is such a remarkably associative device that it bonds those two things very strongly. And this is why people will often say to me, look, you know, Matt, I'm falling asleep on the settee when I'm watching telly, and then I get into bed and I'm wide awake and I don't know why. And the answer is because you've learned the association now that your bedroom is the place of being awake and not asleep. So the advice is the following. If you've been awake for, let's say, you know, longer than 25 minutes, if you've been trying to fall asleep and it's been 25 minutes, or you're trying to get
Starting point is 00:27:16 back to sleep and it's been 25 minutes, get up and get out of bed, go to a different room and in dim light, just do some, whatever works for you, do some sort of gentle stretching. Meditation is fantastic, which we can speak about, or reading under dim light. Don't check your phones, don't eat because they will become triggers for you to start waking up. And then only return to bed when you're sleepy. And there is no time limit for that. And gradually, if you do that, your brain will relearn the association that your bed is the place of always consistent,
Starting point is 00:27:55 solid, sound sleep. And so the analogy I often give here is that, you know, we never sit at the dinner table waiting to get hungry. So why would you lie in bed waiting to get sleepy? And the answer is you shouldn't, you should get out of bed. And so that's the best advice for prolonged time awake and hopefully gives you some back context as to sleep quality versus sleep quantity. Yeah. Thanks, Matt. Really, really helpful. Okay. So I'm going to go back to my sheet of questions. Obviously the world has changed in 2020 because of the COVID-19 pandemic. The way many of us live and interact and work has dramatically changed. So have you seen a
Starting point is 00:28:48 difference in sleep quality, sleep duration? Basically, have you seen changes in the way people are sleeping? And then the follow up to that is, what have we learned this year, if anything new, about sleep and its effects on the immune system. Just taking a quick break to give a shout out to AG1, one of the sponsors of today's show. Now, if you're looking for something at this time of year to kickstart your health, I'd highly recommend that you consider AG1. AG1 has been in my own life for over five years now. It's a science-driven daily health drink with over 70 essential nutrients to support your overall health. It contains vitamin C and zinc, which helps support a healthy immune system, something that is really important,
Starting point is 00:29:45 especially at this time of year. It also contains prebiotics and digestive enzymes that help support your gut health. All of this goodness comes in one convenient daily serving that makes it really easy to fit into your life, no matter how busy you feel. It's also really, really tasty. The scientific team behind AG1 includes experts from a broad range of fields, including longevity, preventive medicine, genetics, and biochemistry. I talk to them regularly and I'm really impressed with their commitment to making a top quality product. Until the end of January, AG1 are giving a limited time offer. Usually, they offer my listeners a one-year supply of vitamin D and K2 and five free travel packs with their first order. But until the
Starting point is 00:30:41 end of January, they are doubling the five free travel packs to 10. And these packs are perfect for keeping in your backpack, office or car. If you want to take advantage of this limited time offer, all you have to do is go to drinkag1.com forward slash live more. That's drinkag1.com forward slash live more. Yeah, two great questions. So regarding sleep and COVID, we have certainly seen quite dramatic changes in sleep. And there's now several scientific papers that have already been published on this. And the way sleep has changed is probably in three different ways. The amount of sleep that we're getting, the timing of our sleep, and then finally
Starting point is 00:31:41 how we're dreaming, which is a fascinating component. Let me start with amount. There was an early report from a sleep tracking company. I think it was almost over 60,000 Americans. And what they found was that nationwide, there was about a 20% increase in the total amount of sleep. Two more recent papers, peer-reviewed papers, one from a European group, one from a US group, both of them suggested that overall total amount of sleep had increased. In one of them, it increased by 15 minutes, the other by 30 minutes during the weekday. And then it had increased by 24 minutes during the weekends. In other words, you know, relative to what most people were sleeping at the weekends,
Starting point is 00:32:33 there was less of an increase, but it was during the weekdays when people got the greater bang for the buck. Also, what we found that was interesting though, is that some people were, there was a considerable portion of people for whom their sleep quality had become much worse. And in fact, there's now emerging this sort of COVID-somnia, as it's being called, which is a form of insomnia that we see now because of the COVID pandemic. Also, a recent report demonstrated that the search term for insomnia on Google Trends has escalated many fold since COVID hit. So we know that this is not quite as, it's not as clean cut as I'm making it sound. It's not just that overall people are sleeping more and people sort of, you know,
Starting point is 00:33:22 having longer durations of sleep. I think what we're going to find is a much more nuanced story. There will be at least two clouds of data. One of them will be a group that is indeed sleeping more, and we'll come on to the reasons as to why. But I think there will also be a cluster, a cloud, for whom sleep has become demonstrably worse, both in duration and in quality. Why? Well, some people have lost their jobs. Other people don't know if they will keep their job. Other people just have high anxiety overall because of the state of the world, understandably so. So I don't think it's as clear cut as those data would suggest. So I don't think it's as clear cut as those data would suggest.
Starting point is 00:34:11 The second interesting part though, which I think is if there is an upside, a sleep upside of COVID, it's the following. It's not just the amount that we're sleeping, it's the timing of our sleep. And what we've discovered is that most people are now going to bed on average about 30 minutes later than they would otherwise, and they're waking up a little bit later. In fact, they're waking up considerably later, and that's how they're getting on average that increase in sleep duration. What this means to me is that finally, because people don't have to get up in the morning as early,
Starting point is 00:34:43 they don't have to build in that commute time, they don't have to get up in the morning as early, they don't have to build in that commute time, they don't have to wake up even earlier to get the kids to school in the morning, you are able to sleep in closer harmony with what we call your chronotype. Are you a morning type or are you an evening type? Now, society is designed for and desperately biased towards morning types
Starting point is 00:35:09 and if anything we chastise the evening types as being these kind of people who are a bit lazy they can't get it together they can't be in work at the office at eight o'clock in the morning and plus i didn't see them at the gym at six o'clock in the morning. So what's wrong with them? And it's not their fault. And we can come on to chronotype because it's largely genetically determined. It's not your fault if you're an evening type. And so I think what's happened with COVID remarkably is that it's revenge of the night owls. That finally we're getting the chance to sleep in a way that's closer to the natural rhythms of our biological 24-hour clocks and less so driven by the dictate and the mandate of society. So I think that's another way the timing of our sleep has changed. The last part of this is dreaming.
Starting point is 00:36:08 We've been hearing, or we started to hear very early on that people was reporting dreaming more and also having COVID dreams. Why is this? Why would that be? I think it's for two reasons. The first is just what we described. People are sleeping later into the morning. Now, previously on our last episode, we spoke about sleep and its structure, that we
Starting point is 00:36:34 have these two types of sleep, non-rapid eye movement sleep or non-REM sleep and rapid eye movement sleep or REM sleep. And REM sleep is the principal stage within which we dream. sleep or REM sleep. And REM sleep is the principal stage within which we dream. But you don't get equal proportions of those two types of sleep with each 90-minute sleep cycle across the night. What happens is that in the first half of the night, that's when you get most of your deep non-REM sleep. But in the second half of the night, and particularly in the last couple of hours of the morning, that's when you get most of your REM sleep. So if REM sleep is the state during which we dream, and now as a society, we are sleeping later into the morning, then probabilistically, we are giving our brain the chance just to simply have more of this thing called dream sleep. So no wonder people are reporting dreaming more.
Starting point is 00:37:29 That's the first issue. The second issue comes on to the specificity, which is, yes, people are dreaming, but why are they dreaming about COVID? What we've learned about REM sleep dreaming, among many of its other benefits, not just in terms of increasing your lifespan and also promoting creativity, REM sleep is a form of emotional first aid. REM sleep provides this type of mental health therapy. It's overnight therapy. And what we've discovered is that it's during REM sleep and dreaming that we take these difficult, sometimes traumatic experiences from the day. And REM sleep acts like a nocturnal soothing balm. And it just takes the sharp edges off those emotionally difficult concerns so that when we come back the next day,
Starting point is 00:38:27 we've processed those emotions and we feel better about those concerns. So in other words, it's not time that heals all wounds. It's time during sleep and specifically dream sleep that provides that form of emotional convalescence. And I think when you have, and we've done this in the laboratory, we've seen this in our experimental work, when you challenge people with difficult emotional experiences during the day, they actually have a rebound that following night where they increase their amount of REM sleep, that following night, where they increase their amount of REM sleep, their dream sleep, as if the brain and the sleeping brain is responding to the demands of your emotional life, because you need more overnight therapy. And so that I think is another reason why people are
Starting point is 00:39:19 dreaming more. It's not just because they're sleeping later into the morning. They also need their dream sleep more to process the difficult, emotionally challenging way of life that is the COVID era. Does that sort of help explain it? Yeah, Matt, that was brilliant, actually. So many thoughts coming up as you described that. It's really quite incredible to think about the REM sleep as emotional first aid. I think it's just a wonderful way to think about it. And, you know, I'm struck by this idea that we touched on last time, Matt, but this whole idea that society is really set up in such a way that so many of us cannot access our basic human rights, which is a great night's sleep. You know, whether it's shift work, whether it's just the general pressures, school start times, it's, you know, if anything good is to come out of what we went through in 2020,
Starting point is 00:40:20 you know, maybe it's a reprioritizing of sleep and going hey look why don't we start changing things school start times office start times the way society is structured because that's what people are up against a lot of the time i think you're so right that what this has taught us is that we don't need to be, you know, anchored or enslaved in some ways in this penitentiary of, you know, the type A personality, work mentality or work schedule. You know, there are so many adaptive ways that we've now developed that allow us to be, you know, I'm not saying we're as productive anymore. And I know there's a lot of challenges for businesses for many different reasons. But when we return to a way of life, I do think that some things will remain subtly different.
Starting point is 00:41:21 And I suspect it will be subtle, unfortunately, but I do hope that, for example, employers realize that, you know what, it's fine for you to, you know, not have to be here until 10 o'clock in the morning. And that way, you know, you can work through until, you know, six or seven, but we've realized that, you know, for that first meeting in the morning, six or seven, but we've realized that, you know, for that first meeting in the morning, maybe you could take it at, you know, 8.30 and do it virtually from 8.30 until 9.15 after you've finally woken up at 7.45 rather than 6.45. And then you can sort of make your way into work at a way and a pace that's more relaxed. And that way you can actually regain what is naturalistically your sleep tendency. I like that idea. I think though the problem is
Starting point is 00:42:12 sleep still has this misperception, whereas it's not the same for diet or exercise. So employers are very, I think, enamored with this idea of saying, yeah, this is great. Let's give you a discount on a gym membership because it keeps you healthy and it keeps you in work and lowers what we call sort of pre-absenteeism at work as well as absenteeism. So I think, and they see that as something virtuous that they, you know, that people are working out. And then with diet, you know, I think, you know, in the cafeteria, developing healthier, you know, selections of food seems to be a good thing. It's a virtue signal from a company, even if they don't really believe in the health benefits to keep
Starting point is 00:43:05 their employees healthier and more productive, even just at the superficial level, they're ready to embrace it. The problem is people have the opposite mentality with sleep, which is that getting sufficient sleep is associated with being slothful or being lazy. And it's nobody's fault. I don't mean to be finger wagging here because most, for, you know, much of the past 20 or 30 years, despite the science changing, people still believe that when we sleep, our bodies simply are resting and our brain is dormant. And there couldn't be anything further from the truth. All of your major physiological systems in your body undergo a dramatic overhaul during sleep. brain are being augmented. Memories are being saved. Memories are being shifted from short term to long term. Your emotional networks of your brain are being recalibrated and retuned. Some parts of your brain are getting reconnected that have been degraded across the day,
Starting point is 00:44:17 particularly with your prefrontal cortex. So you're better able to make decisions and be more rational as an individual. And so as a consequence, you know, in fact, some parts of your brain are up to 30% more active than when you're awake, when you're in certain stages of sleep. But we still have this belief that sleep, because it's a quote unquote dormant state, well, then it's a waste of time. And so why should we actually give people the opportunity to sleep if it's something that we don't see as virtuous? In fact, if anything, we see it as quite the opposite. And why do we see it as the opposite? Because we don't really understand how beneficial and how active and
Starting point is 00:45:00 essential sleep is as a process. I mean, it's the reason that mother nature took 3.6 million years to put this necessity of a seven to nine hour sleep period in place. And for us to come along and think that we can get away with less than that is probably hubris. Yeah. I think one of the many reasons that your first book, Why We Sleep, has proved so popular in so many countries is because it's really hit the site, guys. It's really doing such a wonderful PR job on the importance of sleep and why every single one of us should probably prioritize it more than we're currently doing. I've got to say the stage of life i'm in matt it is i've been moving this way for the last few years but you know my sleep
Starting point is 00:45:52 opportunity is close to non-negotiable and for me i i like to be in bed and you know we're in the british winter at the moment as we have this conversation matt you sure you can remember what the british winter oh i remember that was like um i'm in bed often by half eight quarters to nine i'd like to be asleep by 9 30 p.m and i you're quite an extreme morning type then i am i've always been i love mornings um i I will typically be up five half five and I have a little morning routine and I you know I love being awake and doing a few things before my wife or my kids get up it's it's just how I probably adapted to being a morning type I guess um but what's really interesting is that I've been thinking about emotions a lot recently. And, you know, really, and you touched a bit on this when you mentioned that as we're sleeping longer in the mornings,
Starting point is 00:46:53 we're getting more REM sleep, which is when we, I think, process a lot of our emotions. And there's a form of therapy I've done on myself over the past few years called IFS, internal family systems. And it's really helped me. I feel a lot lighter in my life in general, having gone through this over a number of years. And what's interesting is you go into experiences that you may have had in your life and there's a system of doing it, but you sort of, you reframe them. So you reinterpret them a different way, basically, than you may have interpreted, let's say, when you were a child. And I think that, from what I understand, is that you reinterpret it. And then when you're sleeping,
Starting point is 00:47:37 things get laid down differently. So I guess my broader question is, how much do we know about our emotions and our memories and how they all get rewired and processed when we sleep we know a lot now or at least well i shouldn't say that um we never know enough as a scientist um and i'm always ignorant um and i remain uh ignorant and that's i think the best way to be as a scientist, but we do have some more information, but let me just come back very quickly to what you said. What you're describing is something in the memory science literature that's called consolidation and reconsolidation. So we used to think that the way the memory worked is a little bit like a word document. So you open it up and you type in all of that information, which is you having the experience and acquiring that. Let's say you're in a lecture and you're listening to a lecture. And then you hit the save button on that Word
Starting point is 00:48:34 document, which is what we call the consolidation process. And then at some point you can come back and you can double click that file and you can bring that memory back to mind. You access that memory, you recall the memory. But we used to think that that memory at that point was then fixed, that there was nothing that you could do about it. It would be as though you double click that Word file and now it just is kind of grayed out. And if you try to type in anything, you can't change it. It's just fixed. That's the memory for life. It's not true now. What we've learned is that every time you recall a memory, just like a Word document, you open it back up to the possibility of change. Both you can change its content, you can update it, you can modify it,
Starting point is 00:49:20 maybe you can even remove some parts of it, but also you can update the context and specifically the emotional tenor of that memory. And that's exactly what you're describing. And then you hit the save button. So the memory originally, you created it and you saved it, which is called consolidation, but then you double clicked it, you recalled it, you modified it, and then you re-consolidated it. And so why this is important is for the reason that you described, that if you have a memory that is difficult or painful or challenging from your prior past, it doesn't need to remain that way. And this is what sort of reconsolidation therapy often focuses on. Let's bring that difficult experience back to mind, and let's see if we can restructure it. Can we recontextualize it? Can we frame it in a different
Starting point is 00:50:22 way that's neutral? It doesn't have to be positive, but can we reframe it in a way that's neutral? Or can we reassociate it with something that isn't traumatic and therefore can we dissipate that? So I just want to sort of give you a sort of cognitive neuroscience brain, and you will know this of course already but brain science affirmation of that therapeutic technique what happens during sleep however is is really interesting we came up with um a theory a while back that was looking at emotional experiences emotional memories and at the time we knew that sleep helped strengthen memories. But what we proposed is that when it comes to emotional memories, you sleep to forget and you sleep to remember.
Starting point is 00:51:15 You sleep to forget the emotional charge related to that memory, but yet you sleep to remember the details of that experience. Because let's say that you have a difficult experience, such as a trauma event. Let's say you're a combat veteran or you're somebody, let's say, who's been assaulted. What you don't want to do is throw out that memory. That's not adaptive. Let's say that you were walking home at night and you chose the shortcut to walk down that alley. And then that's where the assault happened. You don't want to forget the important details of that experience because you don't want to walk back down that same alley again. That experience was meaningful and you should remember it. But the pathological part of that, when it becomes something like PTSD, is that the emotion stays with the memory. In other words, every time the
Starting point is 00:52:13 soldier is in the car park at Sainsbury's and they hear a car backfire, that immediately triggers that trauma event of the battlefield. What they are doing there is having a flashback memory. They are not only reliving the memory, the information of the experience, they are also regurgitating the same visceral emotion that they had at the time of the experience. Why is this relevant to sleep? of the experience. Why is this relevant to sleep? Well, what we've discovered is that it's during sleep when the brain essentially depotentiates the emotion. In other words, REM sleep dreaming takes this sort of emotional memory and think about it like an orange, that you've got the fleshy good stuff in the middle, you know, that's the information. And then you've got this bitter emotional rind around the informational orange. Well, what sleep will do
Starting point is 00:53:11 is divorce the emotion from the memory so that when you wake up the next day, yes, you can still remember that information, but what you don't do is regurgitate the same visceral reaction that you had at the time of the experience. In other words, sleep has stripped away the emotion from the memory and that's one of the most powerful reasons why we've come up with this idea of REM sleep dreaming being overnight therapy. You sleep to remember the experience, but you sleep to help forget some of that emotion. That's why to me, sleep is one of the best forms of therapy. And it's the reason I think there's a wonderful quote
Starting point is 00:53:57 by an entrepreneur called E. Joseph Kossman. He once said that the best bridge between despair and hope is a good night of sleep. Yeah, that says it all. It's really incredible, Matt, to hear this because we can talk about sleep for our risk of type 2 diabetes and our risk of cancer, but this is using sleep as a tool. This is using sleep as a way of processing your life, enhancing your life. Who wouldn't want all those benefits you just mentioned about our emotions? We know anxiety, depression, all kinds of things are going up year on year. And there's just so much in that, that if we can get in the habit of really prioritizing sleep, I don't know about you, Matt, but certainly in clinical practice for me,
Starting point is 00:54:54 for many people, the first job is just to give it the priority. Yeah. Like it's just something that gets squeezed in and fits in around everything else. Once you understand that and you can give it a priority, for many people, that's all they need to do. Of course, some people need a bit more help than that. But when it comes to REM sleep, and you mentioned your own tracker that you use, and I want to come on to trackers because a lot of people have questions about that. I think I have noticed that when I don't have a good night's sleep, my REM sleep goes. And I think I've noticed that when my caffeine intake creeps up, that my REM sleep gets affected the most. And I don't know if there's any science behind that. Do we know what things block REM
Starting point is 00:55:37 sleep? And do we know what things enhance REM sleep? We do. And so caffeine, typically, depending on sort of when you're taking it, has been most demonstrated to have an impact actually on the quality of your deep non-REM sleep. your sleep. So you're waking up throughout the night more times. And therefore, when it comes to sort of that consolidated sleep cycle, you may not be getting enough REM sleep. So both can take a hit. Another way that you can do a real number on your REM sleep, if you want to find a way to chemically, potently block your dream sleep, just have a couple of drinks in the evening. potently block your dream sleep, just have a couple of drinks in the evening. And drinking is one of the ways that once again, you will fragment your sleep. You will wake up many more times. Your sleep is much more fragile when you have alcohol in the system. It's much more likely that you're going to wake up. And when you do, it will be harder to fall back asleep. But what we found is that some of the metabolic byproducts of alcohol, the aldehydes and the ketones, particularly the aldehydes, it seems, those things will
Starting point is 00:56:59 potently suppress REM sleep. And in fact, that's why we see in some alcoholics, they have a near absence of REM sleep. And when they actually become, they go through sobriety, there is this massive rebound of REM sleep when they start sleeping sober. The reason is because their brain has been so starved of REM sleep because the alcohol has been suppressing it. So those are two very powerful ways that you can manipulate your sleep because the alcohol has been suppressing it. So those are two very powerful ways that you can manipulate your sleep for the worse. And alcohol, you know, is one of the most misunderstood sleep aids. It's really not a sleep aid at all, but many of us turn to it. We think of the nightcap, but that evidence is very strong. Now, you know, and I want to come on to actually caffeine,
Starting point is 00:57:46 cause it's something I've changed my mind on, um, since we last spoken. Um, but I don't want to sound puritanical. I think, you know, when the book came out, um, you know, some people, I think felt as though the message there, and then I sort of did a TED talk and I think people felt as though perhaps some of that was, you know, a little bit, you know, sleep or else sort of, you know, dot, dot, dot. And I, I understand that. And what I want to say is the following. I don't mean to sound puritanical about alcohol and caffeine. You know what? Life is to be lived to a degree. caffeine. You know what? Life is to be lived to a degree. And I, as a scientist, have no business telling you how you should live your life. All I want to do is share with you the science and the knowledge of sleep so that then you are empowered with the ability to make whatever choices that you want in life for yourself. You know, having, you know, a glass of wine, you know,
Starting point is 00:58:45 a night a week or two nights a week. Sure. You know, I can't tell you as a scientist that that won't have an impact on your sleep. It will. And I can't lie to you about that. But, you know, there is also something to be said for, you know, having something that you like as well. Of course, the politically incorrect advice that I would never share with you is that you should go to the pub in the morning and that way the alcohol is out your system by the evening and there's no problem at all. But I would never say that on a public podcast. But hopefully that sort of gives you a sense of the impact of caffeine and alcohol. But you're right. I think the shift of us understanding sleep is not just about physical health. It's also about mental health. And you spoke, by the way, just,
Starting point is 00:59:34 you mentioned it, anxiety. And I know it's something that, you know, in your books, you've really drawn a sharp focus on mental health, which we don't hear a lot about from doctors. We hear a lot about physical health, but I think it's less so common that doctors help us understand our mental health. And anxiety is a big problem. It is at astronomical rates in first world nations right now. And sleep is a key part of this ingredient too. And we published a study just a year or so ago, which in some ways frightened me. What we found is that when you causally deprive someone of sleep, you instantly trigger a dramatic escalation of anxiety. And it is dramatic. In fact, all of the participants in our study began healthy. They had no signs of an anxiety disorder.
Starting point is 01:00:27 By the end of one night of no sleep, 50% of them had escalated to a level of anxiety that would be clinical grade requiring treatment, which it just blew me away. And what we also were doing, we were assessing their anxiety across the night. And what we found is that there was a dose-dependent relationship. The longer you go without sleep, the more anxious you become. And we discovered what the brain mechanism was regarding that, which I won't go into here for time's sake. But what we also then discovered was that even subtle changes, we did a much bigger study where we tracked people in real world conditions, free living conditions, and we tracked their sleep and
Starting point is 01:01:11 we tracked their anxiety. And what we found was that even modest night to night reductions in your sleep quality were associated with consequential day toto-day increases in your anxiety. So your sleep from one night to the next was dictating your anxiety from one day to the next. And finally, what we found is that sleep and the electrical quality of that sleep, when you get it, actually provides essentially an anxiolytic. It de-escalates anxiety, just as you would imagine. So I just wanted to come back around to that mention of anxiety there too, because we've really recently discovered how causally, not associational wise, causally related sleep is to anxiety. Yeah. Thanks, Matt. And I really appreciate what you said before about sharing information so people can make up their own minds. And that's, you say as a scientist, it's not your job to tell someone what to do. I also feel that as a doctor, if I'm honest, that as a human being, I don't have a right to tell somebody else what to do. But if they ask for my opinion, I want to share information with them and what I think might be helpful. opinion, I want to share information with them on what I think might be helpful. And it's like,
Starting point is 01:02:30 you know, alcohol affects your sleep, right? If people are empowered to know that, then they can make a choice. But a lot of people are under the impression that alcohol is a sleep aid. And you covered this beautifully on our first conversation together, that it's a sedative, it's not a sleep aid. And it's... That's right. Sedation is is not sleep but we mistake that yeah and so with that with that information that individual now can make their decisions that they decide to have a few glasses of wine before beds and their sleep is impacted but they get more enjoyment out of that wine than they do out of a good night's sleep. Well, that's kind of up to the individual really to make that decision. So I want to thank you for making that point. You also mentioned you changed your mind on caffeine. What did you mean when you said that? Before we get back to this week's episode, I just wanted to let you know that I am doing my very first national UK theatre tour. I am planning a really special evening where I share how you can
Starting point is 01:03:33 break free from the habits that are holding you back and make meaningful changes in your life that truly last. It is called the Thrive Tour. Be the architect of your health and happiness. the Thrive Tour, be the architect of your health and happiness. So many people tell me that health feels really complicated, but it really doesn't need to be. In my live event, I'm going to simplify health and together we're going to learn the skill of happiness, the secrets to optimal health, how to break free from the habits that are holding you back in your life. And I'm going to teach you how to make changes that actually last. Sound good? All you have to do is go to drchatterjee.com forward slash tour. I can't wait to see you there. This episode is also brought to you by the Three Question Journal, the journal that I designed and created in partnership with Intelligent Change. Now, journaling is something that I've been recommending to my patients for years.
Starting point is 01:04:29 It can help improve sleep, lead to better decision-making, and reduce symptoms of anxiety and depression. It's also been shown to decrease emotional stress, make it easier to turn new behaviors into long-term habits, and improve our relationships. There are, of course, many different ways to journal. And as with most things, it's important that you find the method that works best for you. One method that you may want to consider is the one that I outline in the three-question journal.
Starting point is 01:04:59 In it, you will find a really simple and structured way of answering the three most impactful questions I believe that we can all ask ourselves every morning and every evening. Answering these questions will take you less than five minutes, but the practice of answering them regularly will be transformative. Since the journal was published in January, I have received hundreds of messages from people
Starting point is 01:05:24 telling me how much it has helped them and how much more in control of their lives they now feel. Now, if you already have a journal or you don't actually want to buy a journal, that is completely fine. I go through in detail all of the questions within the three-question journal completely free on episode 413 of this podcast. But if you are keen to check it out, all you have to do is go to drchatterjee.com forward slash journal or click on the link in your podcast app. So I think in our last conversation, you know, it's very clear that caffeine is no friend of sleep. And it impacts your sleep in three different ways. The first is that it can make it hard for you to fall asleep. And we all know that caffeine is a stimulant. It's one of the
Starting point is 01:06:23 few psychoactive stimulants that, you know, some people will allow children to have, which is an interesting conversation. The second issue is that caffeine will also make your sleep more fragile. So you're more susceptible to waking up throughout the night. And then the third component of caffeine, as we spoke about before, is that even if you can have an espresso with dinner and you tell me, look, I can fall asleep and I stay asleep. So I have no problem. The issue there is, comes back to electrical quality that we spoke about. When we
Starting point is 01:06:55 measure the electrical brainwave quality of your deep sleep with and without caffeine, it's not the same. And so you may not wake up, but you're actually going to be experiencing more shallow sleep rather than deep quality of sleep. And then the next morning you wake up and you don't feel as refreshed. You don't feel as restored by your sleep the next morning, but you don't remember waking up and you don't remember having a hard time falling asleep. So you discount the idea that it could be the caffeine. But now because you're unrefreshed, you're reachingfreshed, you're reaching for three or four cups of coffee in the morning rather than one.
Starting point is 01:07:29 And so goes this dependency cycle. How I've changed my mind on caffeine though is to become much more relaxed because as with so many things, as you know, as a doctor with pharmacology, it's not just the dose, but the timing that makes the poison. And if you look at the evidence, there are remarkable health benefits of caffeine. And
Starting point is 01:07:55 this evidence is so powerful. In fact, there was a recent meta-analysis and meta-analysis is just simply a fancy scientific term, meaning you gather together all of the single studies and you kind of collate them all to get one big picture average. And it's a very powerful method in science. And there was overwhelming evidence that caffeine was very good for de-risking numerous health conditions that none of us wish for. However, if you dig a little deeper, the story is not quite so. So firstly, I'm much more bullish on the idea of people having caffeine, but at the right dose and the right time. So having caffeine before, let's say, you know, 10 o'clock in the morning and in mild to moderate doses, I think is just fine. If anything, I would tell you,
Starting point is 01:08:46 if you like doing that, you should absolutely do that based on the health benefits. But once you get past sort of three cups of coffee, then the health benefits start to take a turn back on themselves. They start to go in the opposite direction. So again, that's the dose. But when it comes to sleep, it's also about the timing. Because we know that caffeine has a half-life of about five to six hours. It has a quarter-life of 10 to 12 hours. In other words, if you have a cup of coffee at noon, a quarter of that caffeine is still in your brain at midnight, and you're not going to be able to sleep as well as you could do otherwise. brain at midnight and you're not going to be able to sleep as well as you could do otherwise. So trying to cut yourself off from caffeine at the right time, but still enjoying it and thrilling in it is just fine. Some people are much more sensitive to caffeine than others,
Starting point is 01:09:37 though. There's a good variability and we know the genetics and the enzyme behind that. So you may not benefit from caffeine, even if you stop at, you know, even one cup of coffee in the morning. Some people tell me they notice it in their sleep in the evening. What I would note is a subtlety, however. If you look at the data now, it's actually not the caffeine. Because when they did the same types of analyses for decaffeinated coffee, they got very similar health benefits. Different types of conditions were benefiting, but for the most part, you've got some wonderful benefits from decaffeinated coffee. So what on earth is going on here? Well, there's a writer, a wonderful writer,
Starting point is 01:10:16 and a good friend of mine here in Berkeley in California called Michael Pollan, who's written some wonderful books. And he wrote a book recently called Caffeine, and he interviewed me for it. And we discussed the science and we really researched the science. What it turns out is that for what people call the sort of the standard Western diet, which is actually a very poor diet, but it's what many people in first world nations eat, they have a poor micro and macro nutrient profile. We're just not eating well. But it turns out that the coffee bean is very rich in antioxidants. And most people, because their diet is so poor, the only thing that gives them an antioxidant dose is their cups of coffee in the morning. So the health benefits that you
Starting point is 01:11:06 get from a cup of coffee are not really due to the caffeine. It's due to the antioxidants that take a joy ride on this vehicle called a cup of coffee in the morning. And that's why you see the health benefits. And that's why you also see the health benefits from decaffeinated coffee. But I've changed my mind. I was probably just too rigid and puritanic. I was just so passionate about sleep. And before the book came out, you know, there really wasn't a health conversation that had been going on at the level that I wanted it to be, at least not that I'd been helping it to happen. And I think, you know, it's like a Richter shot. You sort of, first you go to a sort of extremes and then you find your sweet spot.
Starting point is 01:11:46 And I think I'm coming to a better sweet spot right now. I'm still not perfect, but one of those places I've come to a sweeter spot on, I think is caffeine. That's fascinating. I guess what you're saying about Michael's work and the work you sort of discussed is potentially if we've already got a nutrient-rich diet, right, which of course many
Starting point is 01:12:10 of us don't, I wonder if we already have a nutrient-rich diet, do we get the additional health benefits then from coffee and caffeine? Do you know what I mean? It begs that question for me. You know, I love what you're saying. This is a beautiful's like that's that begs that question for me you know i i love what you're saying this is a beautiful science mind that's on display here you're absolutely right let's now start to if that's that's the associational evidence that's what sort of works we think is happening now let's do some more controlled prospective studies Let's hold constant and optimal, you know, micro and macronutrient intake, and then let's add coffee back to the equation. Do you still get benefits above and beyond that? Because you're right, it's a little bit like oxygen saturation. You know, if you're a patient
Starting point is 01:12:58 in a ward and you have, you know, 98% oxygen saturation, then me putting you on an oxygen infusion is not going to change your oxygen saturation. You're already close to ceiling levels. You're already close to 100% saturation. But if you're 80% or 70% and I give you oxygen, that's going to make a big difference. So what if we were to sort of get people closer to a diet that's almost saturated at 99% nutritional, do you get any benefit from the oxygen mask of caffeine when you place it on? I would love to do that today. I love how you're thinking. Yeah. Well, let me know if you do it so we can talk about it again, because that would be awesome to find out. But, oh, Matt, there's so much to talk
Starting point is 01:13:41 about. We've only got 20 minutes left. So I think let me try and steer this a little bit. I think we should cover, based upon the questions I received, let's cover the trackers, which I think a lot of people want to know about. Let's cover sleep and the immune system. And then we'll definitely finish off with some tips or any new tips that you might have. Of course, we've got more time, we'll go to other areas, but trackers, you mentioned the aura ring before. I don't know if that's a good place to start. Yeah. So, you know, people often ask me that question sort of, you know, what's the best sleep tracker. And when they're asking that, they're typically asking it through the lens of the question of accuracy, which is what is the best sleep tracker in terms of the one that's most accurate. And I would say that right now, you know, there are a number of sort
Starting point is 01:14:34 of gadgets out there. There are wristwatches, there are headbands, there are rings, et cetera. Many of them are quite similar. If they are tracking your heart rate, your heart rate variability, um, many of them are similar in terms of their accuracy. So, um, these sort of rings, these wristwatches, et cetera. Um, I should note by the way that, um, I wear an aura ring. That's my preferred, um, sort of flavor of sleep tracker and full disclosure recently um i decided to join um the scientific advisory board so take everything i say regarding the aura ring with a pinch of salt as a consequence but i was i have worn and bought just about every sleep tracker out there and i'd been wearing the aura ring for about two years before I even considered sort of trying to advise the company.
Starting point is 01:15:28 And the reason I joined the company and I favor Aura is for the following two reasons. The first is that I think it's just as competitive right now as any other tracker out there in terms of staging your sleep. any other tracker out there in terms of staging your sleep. Most of them right now, if they're tracking your heart rate and heart rate variability, not the things that you put under your bed or your phone, those aren't particularly good, but things that you place on yourself, they're about 70% accurate, probably about 80% accurate in determining how much total sleep, and then about 40% to 70% accurate in determining light sleep from deep sleep from REM sleep. And I think looking at the data that I'd seen in independent studies, I felt that aura was as good, if not probably edging into market leader
Starting point is 01:16:16 relative to other things, such as Fitbit or the Whoop strap, et cetera. But the thing that really makes me more excited about that is a different way of answering that question through a different lens. It's not just about the accuracy, it's about the adherence and the compliance. And you know this better than anyone as a doctor. You can come up with the most accurate, you know, wonderful intervention to help someone with diabetes or help manage their weight or help lower their blood pressure.
Starting point is 01:16:52 And it can be exquisite and near perfect, a hundred percent accurate. But if they don't do it, it's useless. So adherence and compliance is just as important as accuracy. So I think about trackers in these two different verticals. So in other words, it's like a two by two matrix. What I want is a tracker that is highly accurate and is also highly adoptable by the user. and is also highly adoptable by the user. And so what I mean, I've become very enamored with the idea of unwearables. And the reason I don't really like wristwatches or even headband devices is that when we go to sleep, we take things off. We don't put things on. And as a consequence, that's why when you look at these numbers, and probably some of these companies wouldn't show you these numbers, but once they start off with these headbands or these
Starting point is 01:17:50 wristwatches, the first week they're tracking their sleep and they're really excited. And then it just drops off. And what you often will say in medicine is what gets measured gets managed. And if you're not wearing it, it doesn't matter how accurate it is, it becomes a useless device. But a ring as a form factor, I found personally, you know, many of us will go to sleep with our wedding bands on or rings on. We don't take those off and they're unobtrusive. And so your compliance to consistently wearing a ring is considerably higher than your compliance to wearing a headband or a chest strap or something that goes on your wrist. So for me, the best sleep tracker is the one that is good in terms of its accuracy, but great in terms of its stickiness.
Starting point is 01:18:42 It needs to be a low friction device. And what I mean by that is, you don't have to worry about charging it every day. You don't have to worry about sort of strapping it on, or when you turn over at night, did you forget to sort of switch it to nighttime mode and it flashes in your face and wakes you up. And you just need to be able to fall into bed
Starting point is 01:19:03 and not even think about it. So that's the reason that I sort of favor the Aura Ring right now as sort of the dish du jour. But again, take what I'm saying with a grain of salt, considering I'm now an advisor to the company. But in truth, I'd been wearing the ring for two years beforehand before I even wanted to consider helping them. I mean, I guess on one hand, measuring it, being aware of it allows you to change it. I wonder if there's a downside here as well, potentially, where we can become obsessed and start looking too much and start not paying attention to how we feel, but more what does the app or what does the tracker say? Is this something you think we
Starting point is 01:19:53 should be concerned about potentially? I do. And in fact, there is some data on this, that there is a proportion of users. We don't quite know how big it is. It may be sort of less than 10%, but there's certainly a proportion of people that suffer from what we now call orthosomnia. Now, ortho as sort of, as you will know, but the derivative of that term just simply means straightening. So you've heard of orthodontics or orthopedic, orthopedic straightening bones, orthodontics straightening teeth. Well, orthic, straightening bones, orthodontics, straightening teeth. Well, orthosomnia is this worry about getting your sleep straight, getting it right. And for some people, when they start to use sleep trackers, rather than it being a beneficial
Starting point is 01:20:36 force in their life that helps motivate them and helps them make behavioral change, just like you said, with your sleep tracker, you can see that when you consume caffeine or when people consume alcohol, it just decimates their REM sleep or their deep sleep. And it's a great behavioral change tool. But for other people, when they start to see that their sleep isn't great or is not what they want, it starts to create anxiety. And the more anxiety that they have, the worse that they sleep. And I would say, if that is the situation, you know, take that sleep tracker, put it in a drawer and forget about it for now. Just don't worry because it's only going to make matters worse. And, you know, falling asleep and insomnia in those situations, I often liken it to trying to remember someone's name. The harder you try, the further
Starting point is 01:21:33 you push the likelihood of remembering that name away from you. And it's the same way with sleep. The harder that you try and the more anxious you become about not sleeping and the more fretful you become in bed lying awake, the less likely sleep is going to arrive to you. So just take a break from sleep at that point. Relax. Don't worry about it. Don't worry about all of these health sort of detriments regarding a lack of sleep.
Starting point is 01:22:02 Everyone has a bad night of sleep. But if you're struggling with insomnia, you don't need to struggle. You know, really go and see your GP. There are good tools out there. You don't deserve bad sleep. You don't deserve insomnia. And there are ways to get around it. But sleep trackers, if you're having that experience, do not wear them. Absolutely let go of them. Yeah. So I bought an Oura ring myself in maybe June, July of 2020. And it's been great, actually. It's been really fun to see the different stages of sleep. The biggest change I've made, because I was doing a lot of stuff anyway, I think, for years that were, you know, as I started to prioritize sleep more, I was doing a lot of stuff anyway, I think for years that were, you know, as I started to prioritize sleep
Starting point is 01:22:45 more, I was doing a lot of the things that I think were helping me. And I wouldn't have said I had a problem per se, but it's when I eat my evening meal and I eat earlier now, I stop eating two to three hours before bed. And that includes snacking because I saw changes in my heart rate, my readiness score. And for me, because I don't use it all the time, if I'm honest, because I kind of feel I've learned what I needed to learn. Like I feel I've been on this growth curve with it and I've seen, okay, cool. I kind of think I'm good at the moment in terms of what I've learned from it, but that is the number one change me. By 7pm, I'm done. Like I won't snack after that. I won't do anything because it impacts the quality and it impacts how much rest I get. And what's striking is that there's actually not
Starting point is 01:23:37 a particularly good scientific literature that looks at the timing of food in its distance from your bedtime relative to sleep quality. However, I hear this so much from people when they say that if they're eating too close to bed, then it will disrupt their sleep quality. And you've had a wonderful series of podcasts with Sachin Panda here who, ironically enough, I think when you and I did our first podcast,
Starting point is 01:24:05 Sachin is down in San Diego, about a seven hour drive from me here up in the Northern region of California. And he's a circadian sleep researcher sort of, and I'm a sleep researcher, he's a circadian researcher. And we love each other's work and we were so simpatico, but we never really got the chance to connect. And then lo and behold, one morning when I was in London, just with Penguin doing publicity for the book, I was out running down by the Thames and I ran past Sachin. I said,
Starting point is 01:24:41 Sachin, what are you doing here? So we had to both fly to London to meet, yet we're in the same state here. But he's spoken a lot about how the digestive tract needs some distance after food consumption in order not to be active and wake you up, particularly with acid reflux. But the other thing too, I think that we need to do these studies. And as I said, I think you're absolutely right. And the scientific studies will bear this out from front to back. I think the other reason is metabolism. And it comes on to temperature.
Starting point is 01:25:16 Because what we know is that when you go to sleep at night, for you to fall asleep and stay asleep, you need to drop your core body temperature by about one degree Celsius to fall asleep and then stay asleep throughout the night. But if you have a large bolus of food right before you go to bed, that will actually be thermogenic. So your core body temperature, because you've just eaten, will actually start to increase. And I think that's an interesting sort of potential hypothesis that we need to test. I also think it's the reason why having, if you're going to have a meal before bed, and some people like to have a snack before bed, and that's okay too,
Starting point is 01:25:55 everyone's different. If you're going to do that though, try to make it a high fiber, high protein meal, but not a high sugar meal because sugar in particular is very thermogenic you know you it will increase your body temperature so you know having some a little bit of greek yogurt with some you know fiber um some kind of fibrous material with it um that's going to be a great little pre-bed snack but don't don't it in there. So you're absolutely right. Yeah. You're tempting me now to try a high fiber, high protein snack now and get the aura ring out and actually see if it makes a difference. I'll let you know what happens there. Matt, let's see if we can get through immune system and some sleep tips if possible in the time you have left? Yes. So I think many of us, of course, are so immune sensitive right now, both from a physiological perspective, but also from a mental state perspective.
Starting point is 01:26:57 There is a very intimate association between your sleep health and your immune health. And I'll just give some examples to impress upon people how strong this is. Firstly, what we know from a study that was published a few years ago is that individuals who are sleeping less than seven hours a night are almost three times more likely to become infected by the rhinovirus, which is the common cold, relative to those who are getting eight hours or more. We also know in a prospective study in over 70,000 women that those women who were sleeping five hours or less a night, were more than 50% more likely to suffer and develop pneumonia, which we know is a critical component of the COVID equation. Why is sleep so great for your immune system? Well, we now know. The first thing is that sleep will actually restock the weaponry in your immune arsenal. Sleep stimulates a collection of
Starting point is 01:28:09 immune factors. The second great part of sleep is that not only do you create more of those immune factors, but sleep sensitizes your body to those immune factors that you've produced. So when you wake up the next day, you are a more immune robust individual. You're both greater in terms of your immune system sort of components, the weaponry as I sort of mentioned in your immune arsenal has increased, but also the receptivity of your body to those immune signals has also increased. And that's why you're so much better from an immune perspective when you are sleeping. And that's why you're so worse in terms of a compromised immune system when you're not getting sufficient sleep. Yeah. Wow. Sleep may well be one of the most important things we can do for our immune
Starting point is 01:29:06 system health. And wouldn't it be great to see some more public health messaging around that? Matt? It would. Sleep tips. Let's see, what are the most important things for people to think about when it comes to getting more sleep? So I think in our sort of last conversation, we went through sort of the typical sleep hygiene tips of sort of regularity, get some darkness at night, turn off those screens, but also dim down half of the lights in your house before you go to sleep. The third is temperature that we've spoken about. Get your bedroom temperature to around about 18, 18.5 degrees Celsius is going to be optimal for sleep. Not lying in bed awake, we've spoken about that, and then avoiding alcohol and caffeine. Those are all good things I think that can sort of help.
Starting point is 01:30:00 But, and I'll come on to a caveat there too. The other tips I have, the first thing is have a wind down routine. You know, many of us expect inappropriate things of sleep. What I mean by this is we think that sleep should be like a light switch. Now for some lucky people, that may be the case. And in fact, I would argue that if you really just fall asleep within a minute or so, it's actually pathological. It means that you're not getting enough sleep. You shouldn't fall asleep that quickly. But many of us think that sleep is like a light switch that we took ourselves into bed,
Starting point is 01:30:35 we turn off our light, and then we should be able to turn off our brain and fall asleep just as quickly. Sleep is not like that as a physiological process. Sleep is much more like landing a plane. It takes time to gradually descend down and you need to build in a routine. You know, with kids, you would never have a kid playing, you know, until right up until their bedtime,
Starting point is 01:30:56 then stick them into bed and think that they can fall asleep. It's never gonna happen, you know? They need a wind down, they need a bath, they need to be read to. You find a wind down routine for them and it works wonderfully. Human adults, just like human children, are no different. So have a wind down routine and that could be having a bath or it could be reading for a little bit. It could be doing light stretching or it could be a meditation.
Starting point is 01:31:23 Whatever it is, find out what works for you and stick to it. That's one of the best pieces of advice I can give you. The next thing is that if you are struggling with sleep, remove all clock faces from your bedroom. Looking at a clock if you're struggling with sleep and knowing that it's 4.23 a.m. in the morning is not going to do you any favors whatsoever. So let it go. Remove all clock faces. Another thing is don't lie in bed counting sheep. The study has been done and it actually makes you have worse sleep. But if you are struggling with sleep and you don't want to get out of bed, per my advice,
Starting point is 01:32:08 and you don't want to do meditation because that's not your thing, a great tip here is to get your mind off your mind. And because one of the reasons that we can't fall asleep is because we start catastrophizing and ruminating, that Rolodex of anxiety. So one trick that they've found that's useful is take yourself on a walk. Think about a walk that you can visualize. You know, it's a walk in the woods or a walk on the beach and take yourself off on
Starting point is 01:32:40 that walk for five or 10 minutes. And then the next thing you realize is that your alarm's going off and you're waking up in the morning. The final thing I would say before the caveat is, I would love it if people could keep technology out of their bedroom. I know it's hard. I know it's so, so hard. The last thing that most people touch at night is their phone. And the first thing that they touch in the morning is their phone. And if you can try just keeping it outside of your bedroom and see if you can hold off until you've brushed your teeth. Just start there. It's the BJ fog kind of approach and then put it in the kitchen and see if you can not touch your phone until you have your first cup of tea. It's sort of keep pushing the boat out. But if you have to bring your phone into the bedroom at night, here is the following rule so that you don't use it in bed. You can
Starting point is 01:33:31 only use your phone in the bedroom if you're standing up. And what will happen is that after about five or 10 minutes of using your phone in your bedroom when it's time for bed and you're standing up, you think, I just don't want to stand up any longer. If you can't stand of using your phone in your bedroom when it's time for bed and you're standing up, you think, I just don't want to stand up any longer. If you can't stand up using your phone, you need to sit down. Then at that point, you've got to put your phone away. And that's the kind of the hack. The final thing I would say, Rangan, is all of these tips I'm giving sort of, you know, here and that we provided on the last podcast. These are tips for people to improve their sleep if you are not suffering from a sleep disorder. And the analogy would be the
Starting point is 01:34:11 following. Let's say I'm your sports coach, and I'm giving you all of these tips to improve your performance, but you've got a broken ankle. No amount of my tips are going to help improve your performance until we get you to a doctor and we get your broken ankle fixed. And it's the same way if you have a sleep disorder. If you have insomnia, if you have sleep apnea, have heavy snoring, none of the tips I'm going to give you are really going to be helpful. You need to go and see your doctor, get that sleep disorder treated, and then come back to these tips matt so helpful so clear uh thank you so much once again for making time to come on my podcast i think you're so welcome matt honestly you you have done such a wonderful job in raising the
Starting point is 01:34:57 profile of sleep and its importance and your work is helping hundreds of thousands of people all around the world. I can't wait till the next time. It's such a pleasure to speak with you. I feel, you know, just I'd love next time I come over and all of this pandemic is over. Let's do another one of these if your audience hasn't lost the will to live because I came on a second time. But also just spending time, I think we're so like-minded and it's just lovely to speak with you and also to speak with someone who has an appreciation of sleep and who's trying to communicate that. Thank you for having me a second time around. Thank you for helping me try and get
Starting point is 01:35:39 this message out. Yeah, my pleasure, Matt. And I can't wait till we get together in person. this message out. Yeah, my pleasure, Matt. And I can't wait till we get together in person. Hope you enjoyed that conversation. As always, I would recommend that you think about one thing you can take away and apply into your own life immediately. If you want more tips on sleep, just head over to my website, drchatterjee.com, and you can see a free five-part video series that I've just created all about sleep. Simply pop in your email and I'll send the videos over to you right away. I want to take a little pause right now and share this conversation with someone in your own network. Do you know someone who struggles with their sleep? I want to send them a link to this episode with a personal
Starting point is 01:36:25 note. This serves as an act of kindness, which has benefits not just for the other person, but for you as well. And if you're looking for some inspiration for the new year, my brand new book, Feel Great, Lose Weight, is available to order right now. It came out just over a week ago. There's already nearly 150 five-star reviews on amazon i'm really really pleased that so many of you have connected with the content in there yes it's written around the topic of losing excess weight but the truth is that most of the ideas within the book are universal and will help you form new habits, understand your own behaviours better and ultimately help you live happier and healthier lives. It's available in paperback, ebook or as an audiobook
Starting point is 01:37:11 which I am narrating and here's a short clip to give you a little taste. Many people I know eat when they're lonely. Once upon a time we always ate together. Families and communities would gather at night to enjoy their food as a connected group. When a hunter caught an animal, the meat would be shared. But we're more isolated than ever these days, and researchers know that feelings of severe social separation are rife and rising in the West. If you're feeling lonely and you don't have those rich, meaningful connections in your life, then that may be why you're spending too much time on the sofa eating biscuits and sweets. You feel like you've got a hole in your stomach, but the hole is actually in your heart. on is my bite-sized Friday email called Friday Five. It contains five short doses of positivity,
Starting point is 01:38:27 articles or books that I'm reading, quotes that I'm thinking about, exciting research I've seen, and so much more. The first one went out last week. Feedback has been wonderful. The goal is for it to be a small yet powerful dose of feel good to get you ready for every weekend. You can sign up for it at drchatterjee.com forward slash Friday Five. A big thank you to my wife, the Dr. Chatterjee for producing this week's podcast and to Richard Hughes for audio engineering. Have a wonderful week. Make sure you have pressed subscribe and I'll be back in one week's time with my latest conversation. Remember, you are the architects of your own health. Making lifestyle changes always worth it. Because when you feel better, you live more.

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