Habits and Hustle - Episode 357: The Future of Anti-Aging: Dr. Adeel Khan's Insights on Gene Therapy, Stem Cells, and Exosomes

Episode Date: June 25, 2024

Are you looking to stay youthful and energetic as you age? In the latest episode of The Habits & Hustle podcast, I sit down with Dr. Adeel Khan and discuss the cutting-edge world of regenerative medicine. New technologies like gene therapy, stem cells, and exosomes may help slow down aging and heal injuries in ways that go far beyond conventional medicine. Dr. Khan explains how therapies like Follistatin gene therapy decreased biological age by 11 years on average in a clinical trial. He also covers mitochondria-boosting peptides, engineered exosomes for skin rejuvenation, and stem cell treatments to reduce inflammation and chronic diseases. This is a must-listen for anyone interested in the future of anti-aging and healing treatments.  Dr. Adeel Khan is an expert in musculoskeletal medicine, pain medicine, and regenerative medicine such as Stem Cells & PRP (Platelet Rich Plasma).  What we discuss… (05:00) Cutting Edge Regenerative Medicine Exposed (14:52) Revolutionizing Regenerative Medicine and Stem Cells (22:16) Navigating Stem Cell Therapy Credibility (25:05) Medical Education and Cutting-Edge Therapies (38:15) Revolutionizing Healthcare Through Regenerative Medicine (48:56) Mitochondria Function and Longevity Tools (56:47) Biotech Clinics and Gene Therapy Development (01:02:45) Eterna Health and Gene Therapy Technology …and more! Thank you to our sponsors: Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout.  BiOptimizers: Use code JC10 for 10% off and shop here: bioptimizers.com/jennifercohen Sleep Me: use code sleepbetter at www.sleep.me/habitsandhustle  Find more from Jen:  Website: https://www.jennifercohen.com/ Instagram: @therealjencohen   Books: https://www.jennifercohen.com/books Speaking: https://www.jennifercohen.com/speaking-engagement Find more from Dr. Adeel Khan: Website: https://eterna.health/  Instagram: @dr.akhan

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You're listening to Habits and Hustle. Crush it. So today, you guys, we have Dr. Adil Khan on the podcast. He is a regenerative medicine doctor. Did I say that accurately? Correct? You did. Yeah. Good. And we are going to really get it into everything, stem cells, exosomes, how to live longer, how to look younger, how to like heal yourself from the inside out and all the things Dr. Khan has, well, he came very highly recommended to me through my very dear friends at mind pump. And then when I went to actually

look at who you were, and like look at kind of like research, you knowing that you're going to be on the podcast. You kind of spoke to and really were on a lot of my friends podcasts. I felt like I was like the last one to know about you or whatever. And I don't know how that was. But you know, you can you can kind of explain to me how you kind of became the the it guy in regenerative medicine. But anyway, I'm glad even if I got you last, I'm happy to have you.

So thank you for being here. Save the best for last, right? Yes. Great answer. Great. Yeah, no, it's, it's interesting, because I always was focused on my work. And I just started getting attention organically, like it was never about my end goal was never to be a social media or have a large following. My goal was always to help people. And I think because my intentions have always been very pure, it turns out that people were travels. And to that end, we've never actually spent any money on marketing, for example. And so you just organically get people and they refer by word of mouth when you do good work. Wow. Well, that's interesting because you started this podcast or you start not started,

but you kind of sent in the conversation we have prior to actually starting, you're like, oh, I was just with Tony last week. And I thought you meant a different Tony, but you meant Tony Robbins, because Tony Robbins is one of your people, one of your clients, correct? Yeah, yeah, he joined our membership program. And I've been working on him for the the last six months fixing his shoulder up, which is doing much better now. Wow. So you can so explain before we get into all the nitty gritty. And there was a lot of it that I want to get into. I have like a ton of questions. Can you just explain for people listening what exactly is regenerative medicine? Yeah, it's an old term that came about because it was this whole idea that we can repair or fix tissue back to the way it was. So instead of cutting something out or giving you a pill, we can actually fix it.

And that's a shocker because obviously we're trained to think we can't fix things in medicine. We're just trained that you can only manage symptoms and that you can't actually reverse disease. But regenerative medicine had this promise and this was like 30, 40 years ago probably when the term was coined. So obviously it's not like it took off right away. Right. We're finally in that era where this stuff is actually happening in real life with real patients. We're helping a lot of people, and it's only the beginning. So that means the next 10 to 20 years, it's going to be absolutely mind blowing in terms of the technology and what we're going to be able to do in terms of repairing tissue instead of cutting things out and instead of just giving pills. So that's the exciting

part about regenerative medicine. So because I also feel like we're in a time and a stage where it's very, very trendy. It's like a hot topic. It's very social mediaable about longevity and how to live to be 120 plus and anti aging and how to pro aging and all the things like I feel like that's so part of our ether, our conversation. So I guess it's not that unusual or weird to me that this has become a hot topic for you, that you became popular and that you're talking about it so organically and that you have all these things. Because I think this stuff may have been or maybe still what's considered cutting edge, right?

Like it was very cutting edge and like only, and it's still kind of, is it still considered very cutting edge, very alternatives? Unfortunately, it's still far from being what's called standard of care. So most doctors don't even know what regenerative medicine is. If you went to your average family doctor, they would probably just be like,

I don't know what you're talking about. And it's kind of sad because medicine takes so long to change and there's something called a translational gap, which is there can be 15 to 20 years before what's being shown in research to be effective gets translated into the clinics of the average doctor. So there's a huge gap and delay. And that's the biggest issue. And that's why this stuff is so important with social media, because people can have accelerated learning and they can actually learn about things and figure out, hey, wait a minute, this might be an option for me or why didn't my doctor tell me about this? It's because your doctor doesn't know.

It's just, they don't have the education. We didn't have a regenerative medicine curriculum in medical school and there still isn't a regenerative medicine curriculum. So unfortunately the clinical work isn't keeping up with the science and the science is rapidly progressing at a pace that's never been seen before.

So like, does this, okay, so can you kind of let's get into so you're a right? Are you a medical doctor with an MD? Right? You're an MD doctor? Yes, I'm not a witch doctor. I am a medical doctor. Well, no, I'm asking you, I know, no, no, I'll be honest with you. I knew it.

Well, first of all, you're Canadian. So I do right away that there has to be some legitimacy to you right away. Because I think a lot of times a lot of doctors run around, they're not really medical doctors to begin with. Yes, yes. They have some other. 100%. Right? Yes.

They have an alternative type of medical degree that, you know, is something else. And then they start doing something that could be very, you know, financially. Exactly. You're right. Chiropractor. Unfortunately, you know, chiropractors, naturopaths, if you didn't see a podiatrist. Exactly. Unfortunately, chiropractors, naturopaths, if you haven't seen, podiatrists, who claim they're doing regenerative medicine. And the problem is it's an unregulated term.

So anyone can just say, yeah, I'm doing regenerative medicine. And it's like, well, what's your actual training and expertise? And how do you even know what you're doing? And so that's the biggest issue with the whole specialty. And that's one of the biggest issues we're working on is how do we standardize this field and create best practices and try to move the field forward? And a lot of that obviously has to do

with doing good research and doing good work. So that's kind of what we're trying to do. And I think for me as a physician, my goal is not only to educate the public, but to educate other physicians that, hey, this might be an option for your patient, why not try something that might be less invasive than surgery and has the same potential upside? That's kind of the way I look at things.

Well first of all, like I was saying, it's like also very costly, right? Like it's not cheap to do stem cells, exosomes, gene therapy, all of these things are, it does make it so these cutting edge things that we're going to talk about are really only available to the mega rich and the super famous because they have the money to pay for it. Right? Yeah. Yeah, it's true. But every technology is like that when it first comes out. Right. I always like to use the analogy of Tesla because I'm a big Tesla fan. And when Elon first came out with I always like to use the analogy of Tesla because I'm a big Tesla fan. And when Elon first came out with the 2010 Roadster, it wasn't a very good car and it would cost it 150,000 and it didn't go very far.

And it was just a bunch of lithium ion batteries like taped together, essentially. And so but who did he get to buy? He got like Tom Cruise and like all these other people and he just got because they were trying to get a better world for the future, which is that environmentally friendly kind of paradigm. And this is kind of the same thing I think about is how do we create a better future for everyone is by making these therapies accessible to the average person. But the only way that's going to happen is unfortunately, the famous and the rich have to do it first and then they'll trickle down because the demand will eventually go up and

you can bring costs down and there's innovation and manufacturing and this all this stuff happens over time. So I see a similar trajectory with what we're doing. I feel like in 10 years, this stuff will be a quarter of the price if not even potentially even less than that, that is now and it's already gone down in the last five years. Really? Okay, so so for an example, let's talk about this one thing that happened. Okay, so a couple of few nights ago, actually, let me let me back up. So there was this thing in LA a few days ago. Yeah, a few days ago, it was a YPO Global Health and Wellness Summit. And everyone from around the world

came in who are in YPO. YPO is called the Young Presidents Organization for people who don't know. And they had all these top health and wellness experts like you know, Huberman was there and Tia was there and the you know, whatever all these people. So then because of those names, all these people come from around the world to listen to them speak, yada yada. And then one night I had a dinner at my house for some of the people who came in town. It was, you know, my husband's very involved by PO. And this guy comes over, it was like literally three days ago, and I knew you were coming on the podcast, but I was so

excited. He was telling me that his friend couldn't come to LA to do the summit, because he was in Mexico getting a gene, he was getting his some type of gene procedure where he was changing, or like, basically changing his genes. It's like, I don't know what it's called. Like it's like literally they're putting something in each and every muscle of his to like regenerate his entire body to become where he was, I guess when he was younger. Do you know what I'm talking about?

What this is called? This gene. I don't know which one exactly, but I don't know if he was seeing me, but we argued. Maybe he was. That's the thing. I said to him like oh my god I have this doctor Dr. Kahn's coming on my podcast next week. He's in Mexico.

He does a lot of these procedures in Mexico. I wonder if your friend Nick his name is Nick is doing it. Was it you who he did he see you? Oh I've seen I saw like a hundred patients in, so I can't remember all the last week. Two weeks ago. So not last week. So it's two weeks ago I was there. But so I don't understand like, is this actually a thing that you can actually reverse your

genes? Well, that's that's might be a little bit far fetched. And this is where the whole issue is the lack of obviously regulatory oversight in those countries. You get a lot of kind of quackery as well. So you have to be careful. But there's a fine line. And that's kind of one of my skill sets is discerning between what's actual good science and innovation versus what's just kind of BS. And so what we do, we do have a gene therapy platform, but our gene therapy has been vetted by many scientists, including George Church, who's

arguably the top geneticist in the world, Aubrey de Grey, who's another top longevity scientist. And not only that, I mean, Toy Robbins has done it obviously, and Brian Johnson, and a lot of people have spoken positively about it online. And it's called fallostatin gene therapy. And that's our technology,

which allows us to insert any gene of interest into your body with one injection via subcutaneous injection in the fat or in the muscle and it'll last for 18 to 24 months. So what this does is we can target any peptide, for example. A lot of people know what peptides are. They're just a chain of amino acids. Insulin was a peptide that was made a long time ago, but now we have designer peptides that can help with longevity.

Volastatin is arguably the most kind of holy grail of longevity when it comes to peptides, but the problem has been historically is that it doesn't stay in your body very long. So fallastatin is not a new molecule. It's been around for like 20 years, but you do the injection and it's out of your system in like 90 minutes. So it's a very short half-life. So it's cleared up and it's basically you have to inject yourself like 10 times a day to have a sustained benefit.

And no one's gonna do that for two years. That's not realistic. So our delivery mechanism basically allows your cells to produce follistatin and then it just goes into your blood and then follistatin does what it does, which is it increases energy, it increases strength, it decreases systemic inflammation. And we've seen some pretty dramatic changes in epigenetic biological age reduction, which is basically how fast is your body aging.

There's arguably, there's not a great test for that at this moment, although there's a company out of Harvard called Generation Lab that measures biological age pretty well. But the point is you can use it as a decent metric to see how fast your body's aging. It's called biological aging or biological clock. So you can have your chronological age, but you can have your biological age and they can be very different things. So we've shown that with one injection that people over age 60 can decrease their biological age by 11 years on average, which is potentially a world record with one intervention. And that's why we're applying for XPRIZE

and a few other things too. But it's quite powerful in terms of the biomarkers, but even clinically as a doctor, it's not just about biomarkers because you know, you can argue that stuff. But to me, what's most important is what is it actually doing to my patient? They have more muscle, they can put on muscle easier, they gain more muscle, and they and we measure DEXA scans so you can actually see that. And then you actually have more energy. And so people, if you're fitterter and you're stronger, you're gonna live longer. That's just a fact.

Right. Let's talk about that. So, well, I've got so many things to talk to you about, but so just let me finish on this gene situation. So the way you described it, did you, were you the one who worked on Brian Johnson, by the way? Yeah, yeah, he did our follow-up stat in gene therapy. Okay, so that's basically the same thing that this guy was doing.

This gene therapy. I mean, you may have seen him for all I know. Yeah, he could have been. Yeah, it's just it's just an injection and it helps increase muscle mass and by this we don't inject all over your body though. So I'm not sure what that is. But it's just one injection in one spot. Is it does it hurt?

And is there downtime or no, that's the beauty of it. It takes literally like two minutes. And it's just a little injection in your arm beauty of it. It takes literally like two minutes. And it's just a little injection in your arm like a vaccine. And there's no real downtime. It's sore maybe at the site of injection for a couple hours. And that's it. So you're saying that the they're saying you don't really have much risk.

Like because it's not very old, it's a very new thing. You can you say like the benefits are this is guaranteed. You can't guarantee any benefit, right? And it's something that you have to kind of keep up. It's not a one and done. So you got to do it every 24 months, you said, to maintain it. Yeah, eventually it does get turned off by your nucleus. So it just means it gets silenced and eventually you do have to repeat it.

But almost everyone who's had it done wants it repeated because they feel pretty great on it. And generally, we've done it for several hundred people now, including we did have a clinical trial that's being published momentarily. And so we do have data, obviously, that supports its efficacy. And the biggest thing is safety. There's been no documented adverse effects

in the three, 400 people that we've done. And the worst case scenario, as you said, maybe that it doesn't make a big difference, but in general, I've done it for many people and it's almost always positive, meaning everyone sees increased benefit. In terms of energy, they have less fatigue, they're stronger in the gym,

and if you do Dexa scans to track, you'll often gain at least a couple pounds of muscle, which is pretty significant, especially if you're getting older and you wanna fight that muscle loss that's so important. I think everyone's kind of getting the message now about muscle as an organ of longevity, thanks to Gabrielle. And so I think what we can do is we can use regenerative medicine to enhance the fundamental

principles that allow you to live longer. And that's basically what we're doing. And that's why I have so many longevity people knocking at my door, because we do have the best technology in the world at the moment when it comes to this stuff. So how do you know when to do something like gene therapy versus like, say, stem cells, or I know that stem cells are typically know to be used for like regenerating something that was like an injury, right? Something that has like an injury. Is it also used for anti-aging? Or not really? Yeah, for sure. Okay. Yeah, because so I like this analogy, which is a great, I think a great analogy for how your body your body is like a city. And imagine there's like different districts. And there's there's this kind of golden library where it houses all the information on instructions on how to maintain the city. And that's the nucleus where the DNA information is, your genetic information.

And over time, that library where all the good information is starts to get damaged and then it can't repair itself. And then so it starts sending the wrong instructions. So who's supposed to fix and maintain that library? It's the stem cells. Their job is to maintain it and repair and fix and be like the guy is the construction workers to go there. But unfortunately, over time, as you get older,

your stem cells get exhausted. That's one of the hallmarks of aging. It's called stem cell exhaustion. So to put this in context, when you're a baby, you have 200 stem cells per cell in your body. And then by the time you're 80, you only have one stem cell per cell. So it's gone down by an order of 200, right?

So basically 200 times less stem cells. So it's gone down by an order of 200, right? So basically 200 times less stem cells. So there's less repair workers, there's less people to help repair and regenerate tissue. And so over time, your DNA starts becoming damaged. And then this leads to mutations, cancer, immune issues, all these other things that we know are all associated with aging. Aging is the biggest risk factor for chronic disease. So if we can slow down aging, we can help people with chronic illnesses. And that's my fascination. My fascination isn't necessarily helping rich people live longer, it's to help the people who are suffering and need actual alleviation of their chronic diseases, as opposed to just symptom management. So then who would use stem cells then it can be anybody

besides so let's say I have like I know if I have a bad knee people or shoulder, that's when you inject it right the stem cells. But can you get them like you're saying overall to help with like the Inflammation or oh, yeah, exactly. So a lot of inflammation exactly and that's so Tony You know He's a patient of mine who's done it with me and we can talk about publicly because he's caught we were doing some content together So he he does intravenous stem cells And for example, it helped to shoulder a lot. It brought down his shoulder pain by 90% after one infusion, but it's the quality of stem cells and the quality of exosomes that differentiates us from everywhere else. And it's a way we manufacture them. And then it's also in a lot of this I learned in Japan

when I because Japanese are so far ahead of us when it comes to this stuff. They've been doing stem cells culture expanded in a lot of this kind of science of stem cells for over 10 years. And it's legal there and it's approved, it's regulated, but in the US it's still technically illegal. So the FDA has made a really outdated archaic decision on how to regulate stem cells and because of that unfortunately the US is just falling behind and so patients have to travel. And the way we grow the stem cells allows us to increase their efficacy essentially and there's a lot of scientific details that we don't necessarily have

to go into but the point is the manufacturing is very important and the way we manufacture them allows us to increase their potency and allows them to stay in your body longer so they're not cleared up as quickly and so when you do an IV, it'll it'll do number one, it'll slow down chronic inflammation. And as you alluded to in inflammation, as it's called is inflammation is probably one of the biggest drivers as to why we get old. And if we can slow that down, and change the profile of your immune system, we can really put a dent in aging and even reverse in certain cases where we've helped a lot of elderly

people who are kind of just aging, so to speak, and you can reverse a lot, you can make them feel 1015 years younger, it's amazing. And how often would you have to get stem who are kind of just aging, so to speak, and you can reverse a lot. You can make them feel 10, 15 years younger. It's amazing. And how often would you have to get stem cells to kind of maintain that feeling and that lower inflammation? It's actually very similar to the gene therapy, which is why our anti-aging kind of package, so to speak, is combining the follistatin gene therapy

with the intravenous stem cells and exosomes, which exosomes are basically just a soup that the stem cells grow in. So if you have chicken soup, this chicken meat part is the stem cells and then the soup, the broth is the exosomes. So it has all the nutrients, but there's no actual cells in there. But the advantage of that is because the problem is when you do IV stem cells, most of them actually get trapped in the lungs. But even though they get trapped in the lungs, they still have all these amazing benefits because they communicate with your immune

system. But exosomes, exosomes are so tiny that they can go everywhere. So they go to your brain, they go to your heart, liver, kidney, everywhere. And so they can help with a lot of brain health. They can help to de-age your brain, so to speak. And especially we have something called engineered exosomes now, which are engineered, like I was saying earlier, to stick around longer. Because the biggest problem, if you're going to take away one thing from this podcast, the biggest problem with cell therapy is the fact that they're cleared up by your immune system very quickly.

So they don't get, they don't stick around very long. So the biggest kind of hurdle right now in regenerative medicine is how do we get these cells and exosomes to stay in the body longer? Because we know they're so powerful, but they're getting taken away by your immune system so quickly. So there's all these cool cloaking mechanisms. I always think, I always talk about like Harry Potter and the invisible cloak.

I don't know if you saw that, but it's basically like you wear- No, I didn't. Sorry. I'm nerdy, I'm nerdy. I'm as a nerd here. So basically- No, I love it, I love it.

He wears a cloak and it makes him invisible. But imagine if we can make the stem cells and exosomes invisible from your immune system, then they can stick around longer and do their goodness. So that and that and there's also something called hydrogels to protect them and coat them. So there's all these technological innovations are happening that are allowing us to make the stem cells stick around longer. So then what are the kinds of stuff? I mean, you just kind of touched upon it, you said that there are lots of different types of stem cells. Because of that, how do people know which ones are

good, which ones are bad? Also, who to go to who not to go to because that like, like you did say, like it is because it is alternative. Still, I think there's a lot of charlatans, you know, people who are not even actual doctors who are who can provide it, where are people getting these things from? Exactly. You know, that's what I want you to answer. And then how expensive is it? Like, what is the price of it?

Yeah, so finding the right doctor can be challenging. My general advice is find a doctor who's actively engaged in research. If they're not actively engaged in research, I'd probably look the other way, because this is still a very new field. And if they're not doing something to contribute to the field, that means they're just in it for the money, which is something

you don't want to associate yourself with. And generally those people are just trying to make a buck. And I'm not blaming them. I know everyone needs to make money, but this is people's health and it's predatory often what these stem cell clinics are doing. They're taking advantage of desperate patients who have lost hope and are kind of just giving them false hope sometimes. And I'm very honest because, and maybe it's the Canadian in me, but all telepatients, you don't need stem cells, you just need PRP

or you just need exosomes, which are a fifth of the price. And it saves them a bunch of money and I can just fix them with that stuff. So I'm always very transparent about what they need. And whereas I find other clinics will just recommend stem cells for everything when it's not always a solution. Sometimes we use peptides. Sometimes we use nutraceuticals. Like there's different approaches to the chronic complex conditions we see. It's not always just a one size fits all and just stem cells for everyone. And so finding someone who does research and ideally has some sort of institutional affiliation because that usually shows some sort of credibility as well. So, for example, I'm a professor at University of Toronto. I teach other residents and stuff like that. And so I think I think that also usually bolsters

some sort of credibility. And then by the way, I want to interject for a second, because I think a lot of people don't know aren't aware of this. For people who don't know in U of T, University of Toronto is really a phenomenal university. It's kind of Harvard of Canada. It is. It's a Harvard of Canada. And I think it's really is. It's a Harvard of Canada. And I think it's really interesting. Malcolm Gladwell had this conversation also with us because, you know, people don't realize that they hear Harvard Princeton Yale because it's very much part of like a vernacular. But the people coming out of Canada, and I'm not just saying this time

Canadian, I'm saying because it's actually legitimate and people who you don't know if you don't know, U of T is the most reputable and it is harder to get in there than it is sometimes at like a Harvard. Just so you know. Oh no, I know many of my friends who are physicians who couldn't get into University of Toronto Medical School, but they got into Harvard Medical School. So it is very challenging to get into medical school, especially in Ontario. Yeah, it's really hard. So's why that's so you are affiliated with you to view of T. Yeah, I'm a professor there. Yeah.

So I teach med students and residents, unfortunately, because I got so busy with everything. I am not teaching as much anymore. But I'm probably going to keep my affiliation for global elective. So even if I'm traveling abroad, residents have the option to come train with me internationally. So guys also like Matt Malcolm Gladwell went there, Jordan Peterson taught there and also you know also same thing. So what can we say, Canadians were a good bunch. Yeah it's true. I just want to give people like apples to apples because you know people don't understand how what U of T is. So why I even want to bring it up is because there is legitimacy just by you saying that you're affiliated with them. There is like, again, I just want to I want to show people there is things are not always equal,

right? Like it doctors aren't equal. colleges aren't necessarily always equal. In this case, like you obviously are a real MD. And, and by the way, yeah, yeah. And you are affiliated with a real university. So did you go to medical school there? I went to University of Ottawa, which is the capital of Canada. I know. I was born in Ottawa. Oh, yes, I was born in Ottawa. Okay. I feel like most Americans don't know what Ottawa is. No, they do not. But it's our capital. It's our capital. So, but yeah, so but the reason I teach and the reason I decided to do that was because I do want to educate the future generation on this stuff because I think it's so important for them to know about it.

And every resident I teach is blown away by the stuff we're doing. And in fact, I recently hired one of the doctors I hired was one of my students. So because they're just so enamored by what we're doing and they're just like, holy crap, how come I was never taught this before? And so it's just that kind of and I love that reaction every time they see what we're doing and they're just kind of like just fascinated by it. And I think it's just the beginning of it too. So it's gonna be exciting to see where it goes.

And then just to answer your other question about the cost, it ranges, if you do a simple exosome procedure for like a joint or something, it can be a couple thousand dollars. But if you do the full package and there's a lot of stuff that we do, you could spend up to $50,000, $75,000. So it's just such a big range. How about stem cells? It just depends on what you're doing. Stem cells, yeah.

So the anti-aging stem cells, which is probably the most common thing we do, ranges from 15 to 25,000. So it's still pretty pricey, obviously. But like I said, a couple years ago, that used to be like 30 to 50,000. So I think it's already come down a decent amount. So what is the difference in procedure between the anti-aging stem cells and let's say the stem cells for an injury like a shoulder or a neck? Yeah, it's actually very important because the anti-aging stem cells are what are called

culture expanded stem cells. So they're grown, we take the umbilical cord tissue, for example, after C-section births, we do a bunch of testing to make sure they're safe, good quality, half our samples are thrown out because they don't meet the quality standards, and then we grow them for three or four weeks. It's kind of like cooking bread or cooking something, I don't know. But if you're basically- Or baking bread? Breaking bread, sorry. Okay, baking bread.

As you can tell, I don't cook or bake. Yeah, apparently not, yes. Yeah, so, but basically when you make the stem cells, it's called culture expansion. So you're growing them. And you have to grow them to a certain amount for them to be useful when you put them intravenously. So if you just put 1 million stem cells intravenously, for example, that's not going to do anything. And that's actually very common in the US. There's all these stem cell clinics offering intravenous stem cells and they're just underdosing

people completely or they're just lying to them and I've seen that happen to many celebrities Again predatory people and so and plus it's also illegal but I mean that doesn't stop people I guess but But so the point is you do culture expanded you grow them and those are stem cells that you want to put intravenously because they're gonna help to regulate your immune system So they're good for chronic inflammation. They're good for autoimmune conditions But if you just have a shoulder issue, you don't need those powerful, you don't need like a hundred million stem cells

in that one area, unless you have really bad advanced osteoarthritis. That's the only time where we really use it. But if it's just an injury for like a tendon or a muscle or a nerve, then we just use exosomes because exosomes, they have all the signaling molecules in there to reduce inflammation, to help heal tissue.

And then we combine them with peptides because they target different pathways. So my co the combination of exosomes and peptides works wonderfully for almost every soft tissue injury whether it's a shoulder, knee, ankle or whatever. And so that's that's usually what I use and I use that for a lot of my pro athletes like I've treated a lot of NHL, NBA, NFL guys and obviously they wouldn't be coming to me if I couldn't do good work, you know what I mean? Because their body is their livelihood. Right. So then when do you use PRP then?

So platelet rich plasma is where we take your own blood, we spin in a centrifuge, and it concentrates the platelets. Hence the name platelet rich plasma because it's rich in platelets. Platelets are little molecules that help to repair tissue. They send signals for growth factors and release growth factors, but it's very limited because it's your own blood and everyone has variability. Some people have healthy PRP, some people don't have healthy PRP.

And if you're older, if you're in your 60s or 70s, you better believe your PRP is not gonna be good as someone in their 20s. So there's a lot of variability and you can't standardize it versus off the shelf standardized like exosome or stem cell products. So that's problem number one. And then problem number two is PRP is not very anti-inflammatory. It's good for promoting

inflammation. So it's actually good for like muscle tears. Or if you have an acute muscle tear, it's great or acute tendon tear and you want to get back to running or put back to sport right away, then it can help shorten the healing window. But it's not good for chronic degenerative conditions, which is what most of society is dealing with. And so that's where stem cells and these exosomes and peptides are much more beneficial. So PRP, I still use it. If I have a pro athlete or bodybuilders, I do work with a lot of them, they tour something in the gym and they come to me the next day, then I'll do, you know, I'll usually do PRP

for them. And it works right away. Like I do it. The only experience I have with PRP was when I got a facial and they did that, you know that, well, now we're using engineer. Yeah, yeah, for sure. We're doing engineered exosomes now for the face. And this is a completely game changer in terms of it's 10 times more potent than PRP. First of all, second of all, it engineered exosomes actually stay on the

they actually stay much longer. I can show you some before and afters after if you want to see them, but it's pretty amazing. So the but this is what we're doing. And we're working with a lot of like a list celebrities now and doing this stuff. And they're going to come to coming down to Cabo and we're doing it there. And so it's just it's going to it's going to become the new vampire facial. Okay, what is it? Tell me. Can you give me engineered? I want to come come to Cabo. We'll do it. I'll come to Cabo. You have to ask me twice. All right, I'm going to book my ticket now. That's amazing.

So explain this to me. So it's tell me what the facial is. This is very interesting. Yeah, it's basically so there are a ton. Again, if you type exosomes California, you'll probably find 100 clinics that are offering it. But the problem is the quality of exosomes are basically useless. Most of them don't do anything because they're basically a water,

the contents in there are dead or they're not very useful or they're just, and now the problem is there's a $500 million black market, exosome black market in the US, which means there's all these manufacturers that are making exosomes and they're illegally distributing and selling them to doctors. This is not, no, this is FDA approved, right? So I'm doing this stuff in jurisdictions where I'm allowed to do it. I don't, I don't necessarily agree with FDA, but I'm still going to follow the rules because I don't want to be one of those shady doctors offering things that I should be offering. And so that's why I work in the places I work.

And the beauty of working in Dubai and switch and all these other places I work is that if we have the approvals and we have the regulation, we're allowed to do these things openly. And so we're allowed to innovate. So for example, the exosomes that we would use for you for the face, they're engineered, which means they're enhanced. There's something called mu cells. This is again a Japanese technology where if you increase the mu content of stem cells, it allows them to survive longer and it increases their efficacy of reducing inflammation and helping with regeneration, collagen production. So it just makes your skin essentially glow, it makes it look smoother, it helps with wrinkles and it can also help with collagen stimulation,

which is always a good thing for obviously skin aging. Yeah, is this also something that you have to upkeep, right? Like you can't just get it one and done, you have to get it done. Yeah, so I work with a Japanese plastic surgeon who's been doing this stuff for a decade and she said it usually lasts for two to three years at least, like this facial. So it's not like you have to do it all the time, but yes, it does last a pretty long time.

I love that. I mean, okay, I'm writing that down. There's someone also in Utah, like I was at this other biohacking conference in London a couple of years ago, and there was people there who said that they were doing they actually they offered me to go to them in Utah to do some stem cells. You don't want to go that guy. He's a natural path. And he's also, yeah, you know, talking about.

Yeah. So I was thinking, like, if they're not legal in the US, how is he doing it? Like, I never understood that. I couldn't, like what Adam was telling me. It's because FDA can't keep up with all the clinics. It's actually very problematic. There's just pop-up everywhere

and FDA can't shut them all down. They literally cannot keep up. They send them letters and some of them get shut down. Some of them keep operating until they get a letter or warning. And then FDA just has to slowly like crack down on them. But they literally can't. There's just too many of them now. So you mean so he's operating in Utah illegally, basically.

But Florida to Florida, California, just if you just dozens of stem cell clinics, but none of them are offering proper stem cells. Number one, often often they're false advertising because they're not offering the expanded stem cells I was talking about. Right. Or number two, they're just doing it, obviously, just without FDA approval and just kind of hoping they don't get caught or waiting until they get caught, I guess, and hoping they made enough money by then. You know what?

That's interesting. That makes sense because when I was talking to Adam, Adam, mind pump Adam, who he said it really helped his psoriasis. I have psoriasis too. It was said it really helped us psoriasis. The stem cells did. Yeah. But when he was telling me he was going to he was actually he told me he was going to Mexico for this. I'm like, well, why are you going to Mexico? There's like all these places I know, like, go here, go there, like in the US. He's like, oh, it's illegal in Canada in sorry, in the US. I was surprised because like I like you were just saying, there are a lot of people,

the people in Utah, a lot of people I figured are like they're doing it here. So can you tell people, is there a way that besides the research and all that stuff that you're saying that they can look for as a doctor, are there certain things that people should look for when they're looking for a stem cell or to know that they're legit or how do they know from one quality or one type to another and people can just tell you whatever they can tell you're not going to know the difference you're not looking at the packaging right so well how do people know exactly it's it's really challenging and I think I don't have a great answer for that to be honest I think the best way is to look at who else word of like trying to rely on people you know

who've gone to the person to get treated. Right, that's the only way you can do it. I wouldn't go to, I wouldn't just go search some random clinic and go to that clinic. I would only go to someone if they come highly recommended by someone you know personally. Because even the problem with a lot of these stem cell clinics, again, this is very predatory,

they'll pay influencers or they'll pay people to do testimonials. So especially with a lot of these influencers, because they make a living off their content. So they'll get free stem cells, and then they'll make a post for them. So you have to be very careful. But you know, that's obviously why I'm trying to create our brand to kind of be the first global brand that's legitimate and credible and offering the best technology and actively trying to do the research too.

Just because Rejerta Medicine is such a wild wild west right now and in East India it definitely lacks some standardization and credit and we're losing credibility because these doctors are kind of ruining it for the people who are actually trying to do it for the right way. So it's very frustrating for me because I get patients all the time who spend so much money and they were basically conned into something because the doctor told them and it wasn't even the right thing or it was even dangerous in some cases because stem cells weren't grown properly.

And so you have to be very careful for sure because you are putting cells, live cells in your body. You don't want to just be doing that willy nilly, so to speak. Is it, could it be dangerous then? Yeah, yeah, because stem cells, if they're not grown properly, so this is a nuance, but it's called the number of passages. So then times the number of times you replicate the stem cells, for example, if you replicate them too many times, it can cause DNA damage,

make them less stable and less likely to survive. So then you just have a bunch of senescent cells that are just dead cells like zombie cells, and then they just send pro-inflammatory signals. So then they can actually cause more harm potentially. So you got to be careful. So that's why the manufacturing details of how they do it is so important. And also optimizing everything. And that's, again, that's why we have protocols

that we've kind of developed with using hyperbaric oxygen, peptides, and all these other things to try to really make sure that we're doing everything we can to enhance the effect of the stem cell and give the best results possible. And like I said, we're also doing a lot of research and essentially all the money that we make

goes back into R&D. That's just the way I want to run our company because I want us to actually be like a research institute more than anything else. I want to take a quick break from this episode to thank our sponsor, BioOptimizers. Let me ask you a quick question. Are you ever just tired of feeling tired? Do you always hit snooze and then slam your head straight back on the pillow or wish you can?

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Okay. So how did you even begin this? So you saw that there was a like when you were a regular doctor, were you actually were you working with patients like just prescribing or Yeah, this is the show right habits and hustle. You gotta Yeah, I want to I want to know what the hustle was. How did you had this happen? Like you what kind of doctor were you? Give me the background like how this whole thing came to be. Yeah, so I was just a general practitioner like a family doctor, which means that just

a general training and then I trained in sports medicine under Dr. Anthony Gallia, who's kind of one of the top sports doctors in the world. He was the one who pioneered PRP injections for sports athletes. He treated Trigger Woods and many other high profile people. And so I learned about PRP from him. So I was very blessed and obviously to have him as a mentor, just because I learned how to do PRP properly. But then I kind of saw some patients not get better. And then also, there were a lot of patients that we couldn't help. And so I kind of was like, Okay, what else is out there?

And so I started venturing a little bit more because and that's, and honestly, it's taking risk is one of the biggest thing I wasn't afraid to take risks. I kind of took a big risk by working in Dubai last year, because I never had lived there before. And I didn't know what it's gonna be like working there. But I just said, Okay, let's just go for it. Let's just see what happens. And I didn't wait. Hold on. Hold on. How did you get to Dubai? That's a long place from Toronto. You know, like, when did you? Oh, okay. Well, yeah, sorry. Let me give you the context. So I treated, I was invited to treat one of the, Mohammed Alabaar, I treated him two years ago.

He owns the six tallest buildings in the world and the Emar properties, which is a Burj Khalifa and a bunch of those buildings. So because I treated him about two years ago, then the following year, because I treated him and it was on social media, I obviously had a lot of people in Dubai asking about me and stuff like that.

So I was like, okay, why don't I just go there and stay for a few months and see how it goes? So I just, but I didn't have enough patience to really be that busy because not like I have a huge presence there, but I just decided to do it anyway, mainly because stem cells are legal in Dubai and you peptides and all the stuff that I'm used to, I wanted to use. So I could get a lot of experience there without having to worry about obviously health care or FDA and stuff like that. And it allowed me to get a lot of real world experience and also learn from scientists who are manufacturing the stem cells who've been doing this for 10 years. And those scientists were from Italy and Italians as well are very

meticulous with the way they do things. And so I learned a lot from them too. And that's kind of how I started getting into this whole world. And then that led me to, I went to Japan to treat someone. And when I went there, I worked with the Sogiatom Medicine Clinic and I learned a lot there too. And that's why I'm working there this summer, just because I feel like Japan so far ahead of what we're doing. And I feel like every time I go there, I learn something new. So I keep on going that way. But definitely the biggest thing is doctors are very used to staying in their box and they and we're taught guidelines and we're taught we're actually taught to kill our creativity which is kind of ironic because we have all these very bright and brilliant people going into medicine but then they're taught to only follow the rules within these

Certain box and if you do if you go outside of these rules you can get in trouble So most doctors are scared to do anything outside of the box. Whereas for me, I was kind of like, okay, well, the stuff inside the box is clearly not working for a lot of people. And look at our medical system, look at our costs, look at everything, like it all points to a failing medical system. So something has to change. So that was always my kind of motivation, I guess, for wanting to pursue this. And so how did how did this guy like I know who he is, he's one of the richest men in the world, this guy in Dubai, and it's the tallest building in the world. But how did how did this guy like I know who he is, he's one of the richest men in the world, this guy in Dubai, and it's the tallest building in the world. But how did he even know about you to even know and even contact you because you were living in Toronto, because he really contact your

mentor that what's that guy's name? Dr. Gallo? No, he contacted me. Well, yeah, it was interesting, because the reason he contacted me was because his personal trainer followed me on Instagram and heard about me. And then I, Oliver was asking who is the best guy in the world for PRP because I want to get it done. And then he was like this guy. So, and so I don't know if I'm actually the best guy. I don't know if I'm actually the best guy, but I guess I'm the loudest online. So apparently you are or at least loud enough that the guy in Dubai heard you, right? Yeah. Okay. So then when do you decipher?

Let's talk about peptides. Peptides is like kind of, I feel like on the totem pole, peptides is like the last, like it goes, I don't know, the gene therapy, stem cells, exosomes, peptides, and then peptides. Peptides is the easiest. And for a while, peptides was very readilyides is the easiest. Yes. And for and for a while peptides was very readily available in the US like I was given a ton of peptides that was given the CP no CJ. Yeah, see, I promote 95. Yeah, that one. BPC 157, which was really good for inflammation as well. Is that the kind of thing? And by the way, the other one though, I just mentioned the CJC was really supposed to be great for like, I think like human muscle mass and blah, blah, blah. Like when you're like to what was it?

What's the yeah, yes, I was on for 10 minutes. Not even I got off it. I didn't like it. It made me really bloated actually. Yeah, and it can cause flushing in a lot of people. So that's a second way that flushing flushing and like make them like flushed and feel uncomfortable. Oh, flushed, oh, okay. Yeah, and so there's a third generation growth hormone releasing hormone, which is what the class of peptides is for that specific one. It's called tessamarylin. That tends to work better.

I heard that one. And that one tends to cause less side effects. So if someone wanted to try a growth hormone peptide, that's the one I'd recommend in general. And again, these things are generally very safe and have very little downside. And they can help and you can cycle them for four to six weeks for anti-aging, longevity, or if you have an injury and you want to help with recovery. But basically, it helps with fat loss, recovery, you can help with sleep. It may help increase muscle mass, like you said, and there's all these cool benefits. And

there's really no downside to like tazamerelin. And then there's other ones that I'm a huge fan of mitochondrial peptides because there's something called the unitary theory of aging. It's kind of this whole idea that there's one root cause of aging and it seems like it points to the mitochondria, which is very interesting because the mitochondria as we learned in high school biology is we thought it was just the powerhouses of your cells, but it turns out they do much more than that. There are these amazing little organelles that evolved like two billion years ago and you have trillions and trillions of them in your body and they actually help to regulate. It seems like they're one of the biggest regulators of what's called tissue homeostasis, which means they help to regulate and maintain your body in

a steady state. And that entropy over time is what actually leads to aging. So if you can maintain the health of your mitochondria as much as possible, that can potentially slow down aging quite a bit. And this is really shown in a study where they looked at a five-year-old who had 0% mitochondrial dysfunction and then a 70-year-old who had 95% mitochondrial dysfunction. And mitochondrial dysfunction just means that mitochondria aren't doing what they're supposed to, which is regulate tissue homeostasis, energy production, iron metabolism,

all this oxidative stress. So everyone's heard of antioxidants. Why are antioxidants good? It's because they help support the mitochondria because they produce free radicals. And when that balance of antioxidants to oxidative stress gets out of whack, so to speak, there's too much oxidative stress, then that's what leads to senescent cells, inflammation, and all these other kind

of hallmarks of aging. So if we can keep your mitochondria healthy, I think that's a great tool for sliding down aging. That's the gist of what I'm saying. And so SS31 is probably my favorite mitochondrial peptide. And the reason is because it can help to restore mitochondrial function and help with the actual anatomical kind of disruptions that happen. So it's a pretty cool peptide. And then there's a few other ones, but that's probably my top one at the moment.

So are they legal? Can I heard they're now banned or in the US? Yeah, like we were going to open a clinic in Florida and I literally just I'm glad that we did it because we were after the FDA banned peptides. I was just like, okay, well, what can I do there? Like, it's just like, okay, so no thanks. I will just open a clinic in Bahamas because it's just ridiculous, yeah. That's crazy. So like, where are people like,

I mean, if people don't wanna jump on a plane, again, this is making it like people have to like jump, like literally jump through like hoops and to get to any type of this type of alternative. I know, I think the only work around right now, unfortunately, which I'm not necessarily recommending is that you can order it off certain websites yourself and you can't get it up. You can't get it through a doctor anymore because doctors are allowed to

prescribe it, but you could, you could technically, no one can stop you from ordering it off a website and, and then self administering it stuff like that. Right. And this doing the shots yourself, but like that to me, I don't know. So then you're saying this SS 31, which is the mitochondrial peptide is the one that you think is the most valuable, right? It's much better than NMS. So have you heard of NMN? Well, I've heard of NAD. I mean, I'm a big NAD person. Yeah, yeah. So exactly.

And NAD is a is a intermediary metabolite for ATP production. So it basically helps to support mitochondrial health, right? And so NMN is also that. It's a precursor that helps with NAD synthesis. But the problem with NAD, like a lot of people do IV NAD, and IV NAD isn't that great because it doesn't actually go into the cells. A lot of it just floats around and just can cause more issues. So you have to take something called trimethylglycine before doing IV NAD if't that great because it doesn't actually go into the cells. A lot of it just floats around and just cause it can cause more issues. So you have to take something called trimethylglycine before doing IV NAD if you're going to do it. But that's not even

the best way. SS 31 is superior to- No, no, that's very- I was going to ask you about that actually. So hold on. Finish with the mitochondria because I'm going to get right back to the NAD. I have a whole thing on and I want to ask you. Yeah. So basically the SS 31 is going to help to make your mitochondria function better. And if they're functioning better, that means they can process the metabolites of NAD and all the precursors better. And they just do what they need to do better, which is maintain that tissue homeostasis,

prevent excessive oxidative stress, and help with cellular signaling and all these other important functions that the mitochondrial are so important for maintaining. So that's why I like SS31. So the problem though is if you're saying people should maybe just buy it on a website. Again, it's about- I'm not recommending that. I'm just saying that's the only option.

No, I know. I know. That's the only option. I'm not recommending that either. None of this is doctor recommended. We're just telling you what's available out there in the world. But the truth is, you don't know these websites. You don't know where they're getting it from. It could be. It's actually not the greatest idea in that sense too. So what are people to do? We know it's out there.

Well, that's why FDA's decision to ban them was nonsensical to me. It was like, why don't you just regulate them and allow doctors to prescribe them as they were doing it to compounding pharmacies? We all know why. It's because they're not patented by pharmaceutical companies and the insurance companies, they can't all make money on it. So that's all it is. And so they know the name of the game and they know how to play the system and this is what they do. So unfortunately for now, yes, you are kind of resort to either traveling somewhere or you have to get them yourself. But you know, I think there is a company called Neo7 that's very promising.

They're using something called augmented peptides and I believe they do are in the process of getting FDA approval to be a licensed manufacturer and supplier to patients and to clinics. So I think that's the most promising one I've seen. So hopefully once they take off, then it'll be more accessible to the average person. And you're saying BPC 157. What is that really good for? Yeah, so that's body protection complex. And that one is called the Wolverine peptide, as some have said, because it helps with regeneration and repair. And the way it does that, a lot of the way is through gut healing. So it helps with repairing the gut lining.

So your gut lining, just to give people some interesting facts, your gut lining repairs itself. It has to repair the lining of the gut every three to five days. So think about all these millions of cells that have to turn over and repair every day. And that's the gut lining.

And there's something called the stem cell niche, which helps to maintain that. But as you get something called the stem cell niche, which helps to maintain that. But as you get older, the stem cell niche becomes less functional, like we talked about. And so your gut lining can't repair itself the way it used to. And so then that's where you get leaky gut, and that's where you can get what are called neoantigens that leak into the blood and cause all these other issues and lead to autoimmunity.

So if we can repair the gut lining through BPC, which it has been shown to help with that, and again, there's very little downside. There's some people saying, oh, can BPC increase the risk of cancer because it stimulates certain growth factors, but it's not about stimulating growth factors. It's about what's the tumor microenvironment.

The microenvironment is a term we'll hear a lot more of in medicine in the next couple of years, because now we're learning at a cellular level what's going on with disease. So the microenvironment is really what dictates whether or not something's going to progress or cause issues. So if you're reducing inflammation systemically, that's going to improve the microenvironment of the tumor. And actually, in my opinion, if anything would help with cancer, it wouldn't cause cancer or increase the risk of cancer. That was my question. Also with the CJC 1295, all of these things

that are touting regenerative cells, even the gene therapy, if there is cancer that runs in your family, isn't there a risk at all for when you're turning over cells quickly or at all? I would think that that can be cancerous, right, or no? Yeah, so it all depends on the signals that are being sent. Like, I would think that that can be cancerous, right? Or no? Yeah. So it all depends on the signals that are being sent. So if the signal being sent is one of mitochondrial dysfunction, for example, where there's loss

of oxidative stress and loss of inflammatory signals, then yes, as they repair and as the cells divide and replicate, they're going to have more and more errors. And then yes, it can lead to more mutations and cancer risk. But if you're improving the cellular environment by improving mitochondrial function or by using BPC to reduce gut lining or to help repair the gut lining and reducing inflammation, or even with like fallastatin, for example, by increasing muscle mass and decreasing,

these are all things we know are gonna improve the actual cellular environment and therefore have in my, have actual positive outcomes on your long-term health. And that's where you have to come down to like, what I always call first principles. What's the root kind of drivers as to why we age? A lot of that has to do with loss of muscle mass

and our gut, our gut, our immune system becoming dysregulated. Those are probably two of the biggest drivers. So if we can make a dent on those two things, then we know overall we're gonna help aging and and the benefits, in my opinion, will much outweigh the potential harms or risks. And again, there's obviously data and studies to back up the safety of a lot of these things. But if you just look at, if you think about it from a first principles perspective, then you realize that, hey, I'm putting on muscle

and I'm decreasing inflammation. This is going to way outweigh the any potential theoretical harm that I might be doing for cancer, which like which hasn't been shown at all. But even if it was, I think having more muscle is going to be way more protective for that anyway. Right. So that's why strength training is so important as you age as well, which is something that everybody can do without going to Mexico or Dubai necessarily. Right. And so the tool to me, these are just tools that can allow you to exercise longer, right? Because why do people start declining? It's because they start getting chronic pain,

they start becoming fatigued, they don't sleep as well, they start just feeling just generally tired. And so if we can give them peptides or we can give them stem cells or gene therapy or whatever it may be in our toolbox, it's just gonna allow them to do these healthy behaviors longer, which ultimately will help with your longevity. And that's that's the way I look at it.

Oh, I see what you're saying. Okay. So yeah, you're saying you're just giving people the tools to actually live longer by doing the things that keep you living longer, basically, right. So let's talk about NAD. So you're right. So any divs, NAD in general, you know, it's all about right. So NAD IVs, NAD in general, you know, it's all about, NAD is all about, isn't it like, replan- it's about replenishing your cells and turning over your cells quicker and for energy and for all these things. What do you think about just incorporating that into someone's day-to-day life to help them with all the things we're talking about with longevity, with aging, with, you know, like this- Yeah, yeah, if we come back to this whole unitary theory of aging, with, you know, like this, all the things we're talking about. Yeah, if we come back to this whole unitary theory of aging, of mitochondria being the root cause of aging,

then anything that's going to support your mitochondria, which NAD certainly will, because NAD is, as we know for sure, as you get older, your NAD levels do decrease, and if we can help to support by increasing their levels, and help the mitochondria to maintain their function, that ultimately will have an impact on aging. Now the problem is, as I was kind of alluded to earlier, was that IV NAD may not actually do what it's kind of touted to do and promoted to do. And it may actually cause more harm because that NAD doesn't actually go into the cell and just floats around and causes inflammation. So you have to be careful with a lot of these clinics that are just promoting IV NAD for everyone. Wow, how do we know? That's a really good one.

Well, the way you would know is if they're sophisticated, even a little bit, they would know to give you trimethylglycine. So if you give trimethylglycine, it's just a supplement, but if you give it with NAD like 30 minutes before, then it can increase the intracellular penetration of NAD. So that's how you would know if a clinic was kind of new what they were doing with IV NAD. That's really interesting because I've gotten that done many times, the IV, not many times, but a few times the IV.

Well, wait till you, so we have something in Mexico for that too, which you can do when you come. So we do something called a placental implant injection, especially the placental tissue, and we inject it subcutaneously into your, just into your fat. And it helps to boost your body's own production of intracellular NAD for about three months. Really? So is that wait, so that's so interesting, because like I was going to say about these

IVs, never when it takes a very long time to go. Also, you're so nauseous. I don't I'm not I was really hard for me. I've done a few times with other like with like, with NBA players, athletes and like, some people are like, can I get it in like 20 minutes, I was like there for two hours. And so it was a lot of these other people actually, the going to guys I know were easy with it. And what I noticed was that the first time I got it done, I felt maybe much more cognitively focused and alert the next couple of days.

The second time I got it done, I think the more I got it, I think I only got it done like three or four times, but the effects or the efficacy did diminish. Did my body acclimate to it or like what was the reason for it? Well, even the first time, like how long did those benefits last? Not very like, listen, not very long. And also I think what you just said was really interesting because how does someone like, I don't think I was necessarily offered that tri methylene.

Glycine. Yeah. Yeah. What, what's going to try it? What say that again? Try it. Yeah. Try methyl glycine.

Try methyl. I'm going to write that down actually. So that's one side. How else would you know if it's actually just, if it's not going into your cell? Is there a symptom that people can feel or? Well the nausea. So that's why you get that. Is that why?

So if you do the trimethylglycine, that should mitigate some of the symptoms. But honestly, again, it's about technology, right? Now I think there's also NAD patches now that are more convenient. And then there's also, I think the technology is improving, but right now, I mean, I like the placental implant because it's a couple hundred bucks

and it lasts for three months and it's such an easy thing to do. And for me, I'm a minimalist. I have such little time and I'm sure you do too. So I can't sit there for two hours doing an IV every couple weeks. Like I just don't have that type of time. Oh God.

And so for me, it's like what can I do that's going to have the most benefit for my health and longevity and with the least amount of time. And that's why I like all this stuff because let's just say you wanted to do all the stuff that we offer. It literally takes like one or two days of your time and then you're good for like two years. Wow. And so do you have a clinic in Cabo you said? Yeah. Okay. And you're in Dubai. Do you have a clinic in Dubai or where? Yeah. Yeah. Clinic in Dubai now. Okay. And in Lithuania, is that what you said? Yes, we're just in the process of setting that up because Lithuania is part of the EU. But but we because we got certain approvals there, we're going to set

up shop there. Yeah. Do you have a partner now or is it just you? It's me for the most part, but I do have a board and investors and all that stuff. And obviously we're scaling up pretty big and being a CEO and also being running and being a doctor is an interesting mix. But I've become very fortunate because, you know, when you do, obviously if you have a good eye for technology, then people want to invest in you. So it's it becomes pretty cool. Wow. Okay. So this is now the business part. I'm sorry, it's going to take me a few minutes to get through this. I have to talk about for two minutes here. So then on the business side of these clinics is your goal to franchise these clinics is your goal just to open up more clinics? Like what is the ultimate goal?

Yeah, my vision for the company is to be more of a biotech and distribution company over time, but probably over the next five to 10 years, we'll open up maybe five to 10 clinics at most, not more than that because they're meant to be kind of exclusive and medical touristy type of clinics where people travel to. So it's not like you need thousands of people to come to

and obviously they're expensive treatments. So the idea is for them to be places where people go as almost like a destination every year or two years or whatever to get their anti-aging stuff done. And so you don't need like hundreds of them. So we're only going to keep them to a handful around the world. And you know, one in Europe, Asia, Middle East, sort of, you know, that type of thing.

And then the plan is to keep on developing the biotech side, which is a technology. So like the mini circle technology, I talked about folistatin, that's just one product. So we have three other products coming out in the next 12 months. We have something called LH gene therapy, which will replace testosterone placement therapy. It'll just be one injection and optimize your testosterone for 18 to 24 months. We have copper gene therapy, which will be good for skin rejuvenation.

And then we also have clotho gene therapy, which will be good for brain health and protecting against neurodegeneration. It may also increase IQ because people who have higher levels of clotho, on average, have a higher IQ of six points. So in our clinical trial, we'll be measuring clotho levels

and we'll see if people's IQ go up, but it'll be interesting to see. Either way, it's good for brain health and people who we'll be measuring clotho levels and we'll see if people like you go up But it'll be interesting to see either way It's good for brain health and people who have higher levels of clotho are protected against dementia Including all zyborgs dementia, even if they have the gene that increases the risk of it So clotho is a really fascinating peptide if you haven't heard about it, but it's really cool. No, I've never heard of that Wow, and so that's do you do hormones as well? Are you doing hormone therapy there? We're gonna have a gene therapy for men, essentially as a way to prevent them having

to inject themselves every day or every week with testosterone, it'll be an alternative where you just do one injection. That's what you're saying, yeah. But you're not doing it yet. Not yet. Not yet. It'll be out in the summer. And yeah, but we do do some hormonal work

because I do have, obviously sometimes hormones are part of the problem, but you can't just ignore them, right? And then we're getting all sorts of chronic complex cases from all over the world. So you have to kind of look at everything. You can't just, if it's just a shoulder issue, obviously we don't have to look at hormones,

but sometimes you're getting these like patients that have been through like 20 doctors and you're like their last resort. So you really have to kind of dig deeper and really look at everything. Absolutely. Wow. Wow, this is so interesting. My god, Dr. Khan, this is I love this. I've learned so much from you. I'm going to come see you in the clinic. I want to I want to try some of the facial and we'll give you a boost of energy and all that stuff. I think you'll love it.

I will. But what's not to love? I'm not going to look 20 years younger. I'm there, you know, like this is amazing. This is amazing. So tell people where to find you. What's the clinic called? What are you called? Where are people going to find you? Yeah. So MiniCircles are our gene therapy technology.

And then Eterna is our clinical services. Our clinics are called Eterna. And obviously, they're in Cabo, Toronto, Dubai, and we're kind of working on an expansion right now. And the easiest way to find me is definitely instagram at dr.acon khan. But our website is eternal dot health. And I know there's always people looking for more information, we have more information on there. And obviously, I've lost the content. And then you can also for people who are suffering out there and may

have lost hope, you can always reach out to us and book an appointment and hopefully we can be of some value to them. Thank you. All right. Well, thank you for being on this podcast and I'm going to see you in Cabo. So, thank you. Sounds good. All right. Bye, everybody.