Mind Pump: Raw Fitness Truth - 2060: Look Younger & Live Longer With Dr. Adeel Khan

Episode Date: January 29, 2024

Explaining how the stem cells the guys got are DIFFERENT than the ones you can get in the United States. (3:04) Why are the U.S. regulators so slow? (9:09) Why he is so confident about the treat...ments he provides. (12:52) 1st vs. 2nd generation stem cells. (15:53) Where does he get his stem cells? (19:08) How does the average consumer know how to wean out the charlatans? (20:12) What are the Asian countries using stem cells for? (21:53) What do people typically notice when they do stem cell treatment for anti-aging/longevity? (23:11) More is better. (25:09) His belief on what stem cell therapy will do to us as a species. (26:20) Breaking down the stem cell treatments the guys got and the profound effects they’ve witnessed since.  Adam. (28:21) Sal. (47:13) Justin. (56:12) What treatment has had the biggest impact on his patients? (59:39) In the future does he see these treatments to be affordable for the masses? (1:07:25) How does he balance his personal and professional life? (1:09:35) Wrestling with manufacturing adversity with his children. (1:16:56) Related Links/Products Mentioned Unlock Longevity event – February 24, 2024 in Austin, TX ** Promo Code MINDPUMP20 - Anyone who uses this promo code will get 20% off their ticket price. ** Special Launch: Mind Pump Fitness Coaching Course ** Promo code 200OFF at checkout for $200 off ** January Promotion: New Year’s Resolutions Special Offers!! New to Weightlifting Bundle | Body Transformation Bundle | New Year Extreme Intensity Bundle Body | Transformation Bundle 2.0  Mesenchymal stem/stromal cells (MSCs): origin, immune regulation, and clinical applications How iPS cells changed the world | Nature Synthetic biology   Mind Pump #1762: Tony Robbins – Life Transforming Breakthroughs In Precision Medicine Exosomal therapy—a new frontier in regenerative medicine Fecal Microbiota Transplantation: An Update on Clinical Practice Caroline GANOBIS | PhD | PhD | University of Guelph, Guelph Regenerative and Protective Actions of the GHK-Cu Peptide Sickening: How Big Pharma Broke American Health Care and How We Can Repair It – Book by John Abramson #263 - John Abramson: Big Pharma | Lex Fridman Podcast A review of vagus nerve stimulation as a therapeutic intervention The Roseto effect: a 50-year comparison of mortality rates. Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Adeel Khan, MD (@dr.akhan) Instagram   Tony Robbins (@tonyrobbins) Instagram Caroline Ganobis, PhD Matthew Wolff (@matthew_wolff5) Instagram John Abramson (@DrJohnAbramson) Twitter Lex Fridman (@lexfridman) Twitter Inky Johnson (@InkyJohnsonMotivate) Instagram Arthur Brooks (@arthurcbrooks) Instagram

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Starting point is 00:00:00 If you want to pump your body and expand your mind, there's only one place to go. Mind pump with your hosts, Sal DeStefano, Adam Schaefer, and Justin Andrews. You just found the most downloaded fitness, health, and entertainment podcast. This is Mind Pump. Oh boy. Today's episode, we brought back on Dr. Khan. This is the guy that's on the cutting edge of science for longevity, for help, for healing, teaching your body or getting your body to regenerate. Like we're talking about stuff that you can't even do here in the States yet. Like it's crazy, crazy cutting edge stuff. He breaks it all down. He is a genius in the field. In fact,
Starting point is 00:00:44 in today's episode, you hear about our experience with him. We actually had to go down to Mexico to use some of these treatments. And Adam alone, by the way, who's been struggling with psoriasis for half his life has seen some of the best improvements he's ever seen. And this guy's been to like every doctor for it. Um, this is wild. If you're like, if you want to know the cutting edge, you want to know what's coming on the horizon next 10 to 15 years, you want to listen to this episode. He breaks it all down.
Starting point is 00:01:09 Dr. Adil Khan, by the way, he's running a regenerative medical conference. This is a, a medical conference. It's called unlock longevity. You can attend. He's got some very well known speakers. By the way, Dr. Khan works with some of the best athletes and celebrities and billionaires in the world. Like this guy is incredible. This conference can have over 500 people. You're gonna learn some crazy stuff there.
Starting point is 00:01:34 And if you go through this link, you'll get a discount on a ticket. You get 20% off, in fact. Go to Eterna, E-T-E-R-N-A. So Eterna.Health, forward slash unlock dash longevity, then use the code mind pump 20 and you'll get 20% off the ticket price. Also trainers and coaches, three days left for the sale and the free stuff with our new trainer course.
Starting point is 00:01:59 We put a course out finally for trainers and coaches that teaches you how to build your business, teaches you how to be more successful. We put stuff in this course that you'll get nowhere else stuff that we found that makes the biggest impact for trainers and coaches. And because it's a launch, here's what you get if you sign up over the next three days free maps, prime program, free maps, prime pro program. You get to attend a live lead generation masterclass.
Starting point is 00:02:23 You get all 11 maps mods for free, all 13 maps guides for free. You get $200 off and you get included in a private Facebook group for trainers and coaches. If you're interested, go to mindpumpfitnesscoaching.com, use the code 200 off for the discount. Also, three days left for the New Year's workout program bundles,
Starting point is 00:02:45 all of them 300 to 350 dollars off. Here's what they are. Okay. New year to weightlifting bundle, the excuse me, new to weightlifting bundle, the body transformation bundle, the New Year extreme intensity bundle, and the body transformation bundle 2.0. If you're interested in those, go to mapsjanuary.com. All right. Here we are with Dr. Conn. Welcome back, Dr. Conn. Yeah, here we are with Dr. Khan. Welcome back, Dr. Khan. Yeah, on my own this time. Hey, that was fun. So we came down, we talked a little bit about this on the show, right? We came down to Mexico, come see you to get some treatments and stuff.
Starting point is 00:03:15 Can we talk about what you did to us and what you gave us? Yeah, please tell the audience how I genetically modified you and put some sounds in your body. It's for only human beings now. Justin's erection has improved by 30% substantial. genetically modified. I put some cells into your body. That's for only human beings now. Yeah. Justin's erection has improved by 30% substantial. Yeah. No, so what's the, so we had talked about that. So you give a stem cell. So let's talk about that first and what, what, what that procedure was like.
Starting point is 00:03:36 And we'll talk a little bit because we all notice a difference for sure. Yeah. So that, so that we'll start with that. Yeah. And I think I have to paint a little bit of a picture because the problem is you can type stem cell into Google right now and you'll probably get like a hundred different stem cell clinics in the US. And then you'll also see FDA warnings.
Starting point is 00:03:52 So I have to go into the history a little bit and explain why the stem cells you got are so different from what you can get in the United States. And so the biggest difference is in the United States, you can do what are called autologous stem cells. So autologous means are from your own body. So you can take them from your bone marrow or you can take them from your fat, but you're not allowed to grow them. That's called culture and expansion where you actually grow the stem cells.
Starting point is 00:04:19 And if we're going to be technically correct, which I like to be is they're technically not even stem cells. They're called committed progenitor cells. What that means is they're already committed to a certain cell lineage, whereas a true stem cell, as most people probably know, has the ability to turn into any type of tissue. That's called pluripotent. And the most basic form of that is what's called embryonic stem cells, which are totipotent, which means they can turn into anything.
Starting point is 00:04:45 But I'm, some people may remember in the Bush era, there was a lot of controversy around stem cells. And the reason for that was because people were proposing that we use embryonic stem cells because they're so strong. But then obviously there's ethical issues, right? It's like, so it's like, we're not harvesting it.
Starting point is 00:05:02 Yeah. Yeah. Exactly. And so that never obviously took off. So that kind of set back the stem cell field a little bit. But then there's a lot of bright people and scientists who figured out, Hey, wait, there's other sources of stem cells that maybe aren't as strong as embryonic, but still have a lot of great properties. And that's where the fat came in. That's where the bone marrow came in. And then that's where umbilical core tissue and
Starting point is 00:05:23 perinatal fluid and all that stuff that comes after birth came in. And then that's where umbilical core tissue and perinatal fluid and all that stuff that comes after birth came in. So in the US, they said, okay, you're allowed to take, you're allowed to take your progenitor cells from your fat and bone marrow, and then you can process it and you can inject it back in. And so this has been done for several years and many clinics offer that.
Starting point is 00:05:40 But the problem is there's so much heterogeneity, which means the quality of your stem cells versus a stem cell of a 20 year old is going to be very different. So it's only going to be good as good as the ones that you can produce. Exactly. And after 40, there seems to be a decline in what's called stem cell exhaustion, which is one of the hallmarks of aging, which means the stem cell number and the function of stem cells decreases significantly.
Starting point is 00:06:01 So they're probably not even that useful after a certain age. Now, what are the stem cell treatments approved for? Cause when I looked it up and read a little bit about it, I think it's just for like certain types of cancers that they treat. So yeah, so the only, I mean, their FDA has a few approved therapies now, but one of them that's been around forever
Starting point is 00:06:19 is for like leukemia, which is like a bone marrow transplant. And that's actually when, and that's been around since like the 50s or. Okay. And that's, that's actually when investment around since like the fifties or sixties. And that's, that's a much more involved procedure. But the cool thing that we realized is those are hematopoietic stem cells. What you guys got are mesenchymal stem cells.
Starting point is 00:06:37 So these are just like embryological terms. But the point is hematopoietic stem cells, you have to have what's called HLA cross matching. So you have to match. So that's why when you see, are you a match for a bone marrow transplant versus what you guys got were mesenchymal stem cells. And if you guys remember, it's not like we had to be like, oh, are you a match or not? We could just give them to you.
Starting point is 00:06:57 And the reason they're safe is because they're immunoprivileged because you don't have to have an exact match. They're not going to cause any sort of rejection. And that's the beauty of mesenchymal stem cells. So mesenchymal stem cells essentially are, they can be from your fat, your bone marrow, from umbilical cord, and these are all the different sources where we can get them, but in the US,
Starting point is 00:07:15 it's currently illegal to take umbilical cord stem cells and inject them into people. That doesn't stop people from doing it. There's loss of clinics doing it, but it's still not FDA approved, which means you're obviously running not only medical legal risks, but then you're also kind of not sure where they're getting their stem cells and what's the quality and all that stuff.
Starting point is 00:07:31 And then the other biggest issue in the US is you're not allowed to culture expand them. So the stem cells that people are using in the US are maybe like, let's say 500,000 to a million in terms of dosing. What you guys got was like 200 to 300 million Wow, so just imagine what's gonna be better just from an intuitive perspective, right? What's gonna be so in the US you're basically getting older quality stem cells that are not expanded and Then you go do a stem cell procedure at some doctor's clinic and then you're like it didn't work And that's the law people's experience
Starting point is 00:08:00 so it's a shame because it's like it kind of ruins a whole stem cell field and the possibilities of it because they're not even being done properly in this country. And that's because of regulators are slow in terms of progressing and keeping up with the science. Because I worked in Dubai for last all of winter and over there, culture expanded stem cells have been legal for nine years. Same thing in Japan for over 10 years now. But so these countries are already half progressive regulatory frameworks, so they can be done safely. But in the US it's still like not allowed. Sorry. Now the ones that we got were the kind of stem cells that can turn into anything. They're pluripotent. So they're not totipotent, they're not embryonic, but they're close to, they're pretty close. Yes, they can turn into many different types of tissue. Okay. So when wouldn't, wouldn't they be able to turn into since they're not theonic, but they're close to that. They're pretty close. Yes. They can turn into many different types of tissue.
Starting point is 00:08:45 Okay. So when wouldn't, wouldn't they be able to turn into since they're not the toe tip open? I mean, for all intensive purpose, like so you could do cartilage, muscle, tendon, bone. Those are the main ones that they could turn into, but not like you couldn't regenerate like a pancreas from it
Starting point is 00:09:01 or like you couldn't regenerate like an organ from it. So, but yeah, so yeah. Interesting. And so we got that dose. Now, why are the regulators slow here? Are there risks that they're afraid of? Are they afraid of? It's gotta be money. Is this going to turn into a cancer cell? This is going to feed tumors. Like what's the fear? What's the risk? No, because there's good data that the stem cells are actually cleared up by your immune system within a couple of weeks. So they don't actually stay there's good data that the stem cells are actually cleared up by your immune system within a couple of weeks. So they don't actually stay there that long. But the stem cells, what they're doing,
Starting point is 00:09:28 so, because think about why are we putting them intravenously? It's not like we want to grow new tissue inside of your body. What they're doing is they're immunomodulating. They're pressing kind of the reset button on your immune system. So they're reprogramming your immune system
Starting point is 00:09:41 from going from pro-inflammatory to anti-inflammatory. This is called macrophage phenotyping, and macrophages are basically white blood cells that secrete cytokines that can create pro-inflammatory environments. And a lot of people probably know, inflammation, which is becoming a popular term, chronic inflammation is probably the main driver, one of the main drivers of aging. And so if we can slow down the inflammatory process, it's going to help with aging, it's going to help with many chronic diseases, and that's what IV stem cells do.
Starting point is 00:10:07 Number one, they're doing immunomodulation, so they're reprogramming your immune system. And how do they do that? They go through the system, you give it to us through the IV stem cells are floating around, they go to- They have a homing mechanism through what are called chemokines that get released from the blood vessels that tell them, hey, come here, come fix this problem. So that's why they can help with so many different issues and they can help with, a lot of them do get trapped in the lungs.
Starting point is 00:10:28 Uh, but even though there's a lot of them trapped in the lungs, there's still enough of them being spread out in the vasculature that allows for systemic benefits. So the biggest thing they're doing is your, is your gut, I would say, working in your gut and helping to kind of change the environment there. Cause that's where most of your immune system is. Interesting. Wow. that's interesting. Okay. So you gave us hundreds of millions of pluripotent
Starting point is 00:10:49 stem cells, which were harvested from. Embilical core tissue. Okay. And they're from non-vaccinated donors, just so you guys know. Okay. Oh. Hey, that's a good thing.
Starting point is 00:10:59 Oh my God, we're good. You are requesting that, right? You are requesting that. Yeah. Is that a thing? Sorry, are people looking for unvaccinated? They are. It's becoming more and more popular. And are requesting that, right? You are requesting that. Yeah, yeah. Is that a thing that are people looking for unvaccinated? They are. It's becoming more and more popular.
Starting point is 00:11:08 And I wonder why, right? Yeah. Is it because they're afraid that the, I just watched this clip of this doctor who, oh, you know who was, it was the Surgeon General of Florida. It was the Florida Surgeon General said, he's like, we need to relax with these mRNA vaccines because we don't know how this is altering your DNA
Starting point is 00:11:23 because there's all these DNA hitching rides to what this RNA and it's going to be changing. So he's like, this is the surgeon general for us putting this thing out. Kind of well. Well, so you guys got something called fallot statin and that was, it was in a mini circle plasmid, the vector. So vectors are basically a way to carry different genetic material into your body. Right. So the vector we use is called a mini-circle,
Starting point is 00:11:45 which comes from E. coli, but there's no live bacteria in there. And the beauty of the mini-circle plasmid is that it's non-immunogenic, so it doesn't trigger your immune system, and there's no off-site targets. Versus the COVID vaccine, it's a lipid nanoparticle, so LNP,
Starting point is 00:12:02 lipid nanoparticle vector. And what that does, unfortunately, as we now know, is there's offsite targets and it's immunogenic. And you're using that to transmit the DNA, which is the mRNA. So the problem is the vector itself wasn't that great to begin with. So that's why there's people, and I've seen it clinically, is where people get weird reactions. You're like, why is this happening with the vaccine?
Starting point is 00:12:24 Like this shouldn't happen. It's because the lip and nanoparticle is having off-site targets and stimulating their immune system in some people. It's not, I'm not saying everyone, but there's obviously some people who are, have this propensity to be sensitive to it. And so, because of that lip and nanoparticle vector, they're getting all these weird side effects that you don't see with other vaccines. Wow. Okay. So, so you give us the stem cells, the pluripotent ones. And then you said, fallow stand. So let's talk about, wait, we, before we go into the fallow stand,
Starting point is 00:12:50 I want to ask more stem cell questions that I'm curious about because I had such an amazing response from it, like so amazing that it's like, it makes me want more, right? Cause it's like, this is the best my psoriasis has ever been since I've pretty much have had it. Uh, it's not completely gone not completely gone, but it has been suppressed so much that, of course, I have this desire to have more. Is there like an upper limit or what has to stop me from getting five times? Well, exactly. And there's been trials on this. There's been clinical trials with inflammatory bowel disease, for example, IBD, and they put patients into remission, but some of them ended up needing like eight infusions. Okay.
Starting point is 00:13:24 But so they just, they were like, is there an upper limit? That was basically the question they were asking. So is this why you were so confident when- Yeah, I was basically like, because you were like saying- Yeah, I was like, if you're able to see this through, we'll get you there. So okay, so that's why you were so confident.
Starting point is 00:13:36 You're like, I know we're gonna get this, is whether we get it in one, two, or eight treatments is what you're thinking. And that's where it comes back to, I think we talked a little bit last time, was first principles. Like in physics, first principles is like, okay, where are the laws governing mechanics
Starting point is 00:13:51 and gravity, all that stuff. In biology now, they're called fundamental principles or fundamental hallmarks of aging. But aging is the most complex disease, if you think about it. Because if we can cure aging, we can almost treat every other chronic disease because everything else is less complex than aging. And so there's now there's like 12 hallmarks of aging on the most recent
Starting point is 00:14:12 kind of papers. And so those 12 hallmarks kind of governed so many different chronic diseases. So they're like, it's like mitochondrial dysfunction, telomere attrition, chronic inflammation, stem cell exhaustion, genomic instability. I could list all of them, but the point is there's all these different hallmarks that govern why your body ages, and that's the same thing with psoriasis and many chronic diseases. It's the immune dysfunction, it's gut dysbiosis, it's chronic inflammation, like it's all these things.
Starting point is 00:14:41 And if we're targeting at a cellular level, now we understand that's why we can treat you, and that's why we can treat you. And that's why I'm confident with a lot of these treatments because people are like, how do you know? I'm like, because I know what the underlying causes is. It's very different because in medical school, like even though I didn't go to med school, it's not like I'm like, you know, that old. But like when I went to medical school, they used to teach us that you can't infer just
Starting point is 00:15:01 because you have a mechanistic basis doesn't necessarily mean that this is going to work in clinically. But I think that was true 10 years ago, but now the science has evolved so much because of what's called single cell resolution, like spatial imaging, where you can actually see down to a cellular level what's happening.
Starting point is 00:15:17 And you can really understand specific mechanisms and target those with peptides, cell therapy, gene therapy, that you can save with good certainty that if we target the specific problem with peptides, cell therapy, gene therapy, that you can save with good certainty that if we target the specific problem with this intervention, because we know exactly what the problem is, it's going to work. But it's a very different way of thinking because it's not like the conventional medicals where it's kind of like very system-based, where it's like, okay, you see a dermatologist, but the dermatologist doesn't know how all the body's connected in the
Starting point is 00:15:44 different, like all those different kind of mechanistic ways. The dermatologist doesn't know how all the bodies connected in the different like all those different kind of mechanistic ways Yeah, the dermatologist just sees a skin problem and so they give you a cream Yeah, that just gives you a stare and that's that's the way we're taught so so is there a difference though with like stem so that you like Injects in terms of like trying to to address like any kind of connective tissue damage or you know Like if you're just, if you're directly targeting localized, yeah. Like, so it, or is it like, is it the same actual like stem cells themselves as just the way the application of it that's different?
Starting point is 00:16:17 No, it's, yeah. So right now, let's call it first generation stem cells. So these are culture expanded stem cells from umbilical cord tissue. So we can use them into like tendon tears, muscle tears, and we can do direct injections and we can regenerate tissue. That works great. That's something we've been doing for like many years, even with just like plasma injections that it can help. But now, second generation is where you're going to get more specific cell lines to repair specific tissue. So second generation is what's called the Yamanaka stem cells.
Starting point is 00:16:48 So Yamanaka was a Nobel Prize guy and 10 years ago who figured out cellular reprogramming. So basically he's like, okay, if you overexpress these different transcription factors, you can basically take any somatic cell in your body. So I could take a muscle cell or a skin cell in your body. And I could take a muscle cell or skin cell in your body. And I can get a heart or something else. Yeah, exactly. And so your base and well reprogram it first into a baby stem cell, which is almost
Starting point is 00:17:11 like embryonic in state. And then you can differentiate it into a heart cell or differentiate it into a pink, a beta eyelid cell. I don't know when this happened. It was big news. Yeah. But so basically, if you think about it, you're de-aging the cell number one and number two, you're giving it the potential to differentiate into whatever cell line you want.
Starting point is 00:17:27 So for example, some of the research we're doing now, so those are called induced pluripotent stem cells, IPSCs, or for people to remember, I think it's just called Yamanaka stem cells, easier to remember. So let's say you take a Yamanaka stem cell and now what we're going to do, for example, is we're going to differentiate them into beta-yelid, and then we're going to transplant them into the pancreas for diabetes. So that's one of the trials we're going to be doing later this year. So when I hear this, if I were to be fearful or whatever, I always think, okay, well, what if you produce a cell that won't stop replicating? Is there a fear of that? Yeah, there is. And that's exactly with IPSEs because Yet the Yamanaka stem cells the problem is because they're like embryonic
Starting point is 00:18:07 They can grow into tumors or teratomas because they're too strong They have too much stem nests and that's why the cells you guys got are great because they have a finite ability to How do they do that? How do they make it finite because they're Dr. Mazenka mole and origin So it's a different cell origin lineage different lineage so they can't go in that they can't go in that direction Whereas Yamanaka stem cells can go in that direction. So the technology we have if there's a gene edit on that technology So this is this is really cool. It's called synthetic biology It's basically where you can engineer these cells and you can gene edit them and manipulate them That kind of the way you want and so these gene edits are done in a way to prevent tumors or or uncontrolled proliferation. So that's the technology we have. So it's an anti-cancer almost?
Starting point is 00:18:49 Yeah, it won't cause cancer. Wow. So IPSC, but that's the risk with Yamanaka stem cells. And that's why I would caution people to go because there's still probably a 1% chance that they could turn to tumors without that gene edit. But the gene edit is a company that has a patent on it and they're working exclusively with us to develop different cell lines. Yeah, okay, so that's the other question I was going to ask. So yeah, it looks like, you know, I know you, I like you, I trust you, like where do you get your stem cells?
Starting point is 00:19:13 Like where are you getting these supplies? Are they from the same places that the American produce, you know, providers are getting their supplies? No, we have our own manufacturing facility in Mexico for the ones you guys got. We control the way stem cells are harvested, obviously tested, all that stuff. There's a lot of testing done, but the biggest thing I think to understand is how you grow the stem cells.
Starting point is 00:19:34 If you don't grow them the right way, it's called replicative stress, like how many passages you do, so how many times you change them from one cell culture flash to another. If you take them too many times, it causes stress to the DNA. And then the stem cells can actually be harmful. And a lot of clinics are using cell passages, like six passages, eight passages. Some are using 10. We limit ours to three. So and that's something I've learned in Asia and Japan. That's what they, that's what they do over there.
Starting point is 00:19:59 And I was like, how come? And they, they obviously explain. And so the passages is very important. As far as I know, we're the only ones on this side of the world doing that. And so we're limiting the passages and that allows for higher cells, viability. So anytime a market like this emerges,
Starting point is 00:20:14 also out comes all the charlatans and the people. So how does the average consumer know? And of course, what the charlatans will do is they'll find somebody reputable like you use the information science You talk about and we have same stuff chief 50% off yeah, you see that all the time. Yeah, so explain to me What are they doing? That's probably shady to try it to make that happen and how hard and difficult is it for the person? Who's seeking this out to know really hard. it's really hard because even a lot of doctors and
Starting point is 00:20:46 celebrities, I've had people who like have pretty much, you know, unlimited money and resources and have access to any doctor in the world and they've gone tricked. Oh, well. So if they've gotten tricked, how is the average consumer gonna figure it out? And I think, I think the biggest thing I would say is if you're gonna get these procedures done right now, make sure the person you're going to is doing some sort of active research. Like they're not just doing this because if they're only doing this, they're clearly just interested in the money and the business model because right now this is still a very new
Starting point is 00:21:15 field and you need to be actively engaged in the research side to really understand the clinical translation side. So like I'm doing multiple clinical trials like in Canada and other places and so I'm very engaged on the research side which allows me to kind of liaison with all these amazing scientists from around the world and I learn from them and then I can learn from them and translate it clinically and I can be like, okay, this is how we can improve our manufacturing process. This is what's coming down the pipeline and just keep trying to improve. Whereas a lot of these stem cell clinics like in Panama and other places,
Starting point is 00:21:45 they've just been doing the same shit for like 10 years. And they're not really interested in innovating and they're not really interested in like- Just making money. They're just making money, yeah. Wow, so you said in Japan, they've been doing this now for almost a decade. What are they doing them in Japan for?
Starting point is 00:21:58 What are the applications? So by far, the most common is definitely anti-aging, which is similar to what you got the IV stuff Because that's really popular in the Asian community now. It's a growing trend But then cancer is another one. So they're using different type of cell therapies for cancer. So these aren't Mzenkomo stem cells, but they're called natural killer cells and dendritic cells, which are part of your innate immune system So natural killer cells as as the name suggests, they're killers. They help to kill cancer.
Starting point is 00:22:27 And then dendritic cells are cells in your immune system that help to present these cancer cells to the natural killers to help your immune system to fight the cancer. So what happens with cancer is it becomes immunovasive, that's one of the hallmarks of it, meaning your immune system can't recognize it and it can't do what it's supposed to be able to do, which is kill these aberrant cells. And so this just gives your body kind of like the armor and the mechanisms to kind of fight it off. Are they doing like an adjuvant therapy to like chemo?
Starting point is 00:22:52 Yeah, exactly. A lot of times it works in conjunction or a lot of the patients have tried everything and they're still like looking for less options. And I've had, and I saw it in Japan for a stand, like they have stage four like pancreatic cancer patients who are still alive 10 years later because they underwent the immunotherapy
Starting point is 00:23:05 with natural killer cells and dendritic cells. So after that, I was like, holy crap, there's obviously something to this. So yeah. What do people typically notice when they do this stem cell treatment for let's say longevity or anti-aging? I mean, we'll talk about our experience.
Starting point is 00:23:20 Yeah, yeah, I'm curious to hear what you guys have to say. But what do people normally report? Yeah, in general,'m curious to hear what you guys have to say. But what do people normally report? Yeah, in general, the biggest thing is recovery, sleep, energy. I would say like those are like vitality. Vitality, exactly. Sometimes it is obviously very subjective in that sense, but if you measure HRV, for example, we'll see people after IV stem cells or HRV will improve quite dramatically.
Starting point is 00:23:42 So I think just the recovery aspect of your body gets a lot better. And then depending on how chronically inflamed you are, some people actually feel the effects of aging, right? They're like, I'm achy, I'm stiff, I wake up, I'm kind of slow. And then after doing this stuff, they're like, man, I feel like 10, 15 years younger. So what does that mean?
Starting point is 00:24:00 That usually means they're just like, they're not as achy, they have more energy, they can walk faster, like all these cool things. So I remember, because I've obviously done it for my parents and I did it for my dad. And then my father-in-law was like, because I hadn't done it for him yet. And he's like, and then he saw my dad walking.
Starting point is 00:24:15 He's like, why is he walking so fast? He's like, what did you do for him? And I was like, so he's like, I want that. So it's like, very cool. I wish we would, you know, my only regret was that we didn't go do our biological age. Yeah. We just did that recently.
Starting point is 00:24:29 Yeah. And I'm like, damn it. No, no, that would still be, because the epigenetic changes for the biological age take three months. Oh. So you guys, it wouldn't have affected the significance. Wait, when did we go?
Starting point is 00:24:38 When did we come see you? December. Okay. So we're okay then. Yeah. So we can do another one. Oh, exciting. Wait a minute, hold on a second. Oh, that's exciting.
Starting point is 00:24:45 So hold on, when do we feel the full effects then of the stem cells? Is it three months later? Four to six months, yeah. Wow, so what we're feeling now. It's just like early, yeah. We're not even noticing much. I mean, the fall of statin would have kicked in.
Starting point is 00:24:55 Yes, yeah. But the stem cells fully kick in around four to six months for recovery and sleep and all. Really? But some people may notice it. Like he noticed it pretty early, right? Which is, but just a big range. So, so yeah.
Starting point is 00:25:05 Interesting. Okay. So let's talk about what we all experienced so far. Cause this is only one last one last one last. Cause I want to stay with the thing that I was asking about, like, you know, doing it all the time. And I know you can't share specific patients, but, uh, I would imagine if I was Uber wealthy, I would be hooked up to this fucker every month with you.
Starting point is 00:25:29 Yeah. I have, uh, I mean, I can talk about Tony Robbins because we posted online. Like Tony Robbins does IV exosomes every month, and then he does the stem cells every six months. Wow. Yeah, I feel like he's also worth $500 million, right? Yeah, yeah, yeah. Because these are not cheap. These are not cheap. So what I'm so fascinated with then is you telling me that, yes, more is better type of deal.
Starting point is 00:25:49 Yes, there's people that are doing this. It's like, let's fast forward 15 years from now. Like where is the worst? Exactly. And we're going to be able to see like... My vision for this is you eventually you can go to your like even general practitioner and be like, just you go every two years as part of your annuals and you get these gene and cell therapies done and they're covered by insurance ideally because they're slowing, because they're aging as a chronic disease
Starting point is 00:26:07 and it's being defined as such now. And if we can treat aging in a meaningful way, you're going to prevent so many other chronic diseases. But then that's not necessarily good for the system, right? Because you're keeping people healthy. Right. Yeah. So they're going to fight.
Starting point is 00:26:19 But okay, so your sense of everybody I've ever talked to, you have to have the most experienced knowledge, hands-on stuff with anti-aging. And there's lots of stuff online and people touting, oh, we're going to live to 130. You know, like, what's your belief on like our generation and the generation coming back? Like what the what stem cell therapy is going to do for us as far as a species, like living longer? Well, because of the cellular reprogramming, it's real, is really possible that we can reprogram yourselves to a very previous like DH state. And that's something that can happen, I think, in our lifetime.
Starting point is 00:26:57 So I'm not saying we're going to live forever, but I think we could definitely push the boundaries well into our hundreds where we're living a high quality of life Meaning we have loss of energy. We have lost the strength vitality even in our hundreds Wow, so that's what I see Just with the current therapies. Oh, I think with the right right That's not even saying what does it evolve in ten exactly because it's imagine imagine you can come This is what I think would be the craziest thing. We can basically sell you a week reprogram all your old cells and make them all young again Hmm, how often do you get some cells? I do them every year. Yeah, so every year you just hook yourself up Yeah, and then I do the IV exosomes every six months, which are were included in your guys now with exosomes
Starting point is 00:27:36 What are the exosomes are so if I would say if you have chicken soup the chicken the meat part is the stem cells and the broth is Exosomes so it's kind of the broth that the stem cells grow in. So there's no cells in there, but they have all the cytokines, all the growth factors and anti-inflammatory signals. So because there's no cells, they're not gonna last as long because the cells are what signal to your immune system to have that reprogramming effect, but they still have a anti-inflammatory effect
Starting point is 00:28:00 and de-aging effect. And if you put them in combination with the stem cells, they'll have the synergy effect. There's synergy there. Is there a reason to ever do one without the other? effect and de-aging effect. And if you put them in combination with the stem cells, they'll have the stem cells. Exactly, yeah. There's a synergy there. Is there a reason to ever do one without the other? Yeah, sometimes we do, I mean it's merely price to be honest,
Starting point is 00:28:12 but exosomes are cheaper. So I would say if some people can't, you know, they can't, if they can only afford one thing, then we'll just do the exosomes often. Interesting. All right, you wanna talk about what you felt? Yeah, go ahead.
Starting point is 00:28:23 Well, I mean, I think you should start because yours was the most profound so far. And I didn't even know that we didn't feel the full effect. Definitely, that was crazy. That's visible, that's for sure. Yeah, I mean, we all see it, because he's got, I mean, his, Sirisces is, I mean, he's obvious.
Starting point is 00:28:36 And he's been showing us every day, and it's like, whoa, dude, that is weird. I mean, I noticed within 48 hours. Yeah, that's crazy. Yeah, yeah. Like it was that means your body was probably in an acutely flamed in flame setting. Yeah, it was it was.
Starting point is 00:28:49 So I got like really excited. I was like, oh my god, this is for sure going. If you know, because it was starting to go, I definitely feel like I'm I've the results slowed down. Like they were like it felt like week over week. I'm like, oh my god, this is just happening. It's going away. It's going away.
Starting point is 00:29:02 It's going away. And now I feel like and there's like spots like I have spots that are gone. They're just they were there. Now they're gone. Really? And then my bad spot. Oh yeah. Yeah.
Starting point is 00:29:11 No, like I had spots on my head that were super. There's ones on his legs. Yeah. And the and even like the spot on my shin is almost complete. Like you you could actually only tell because the coloration of my skin is different. Like it's like it doesn't look raised anymore. Yeah, it's not raised at all. It's just like a lighter color.
Starting point is 00:29:28 And I bet you if I actually were to spend a week with it. That's the one that you always show us. You always showing us that. Yeah, yeah. That's the one that I've noticed. The one on my rib cage, which is my worst site, again, is completely shrunk down, has been suppressed. It's not as raised at all.
Starting point is 00:29:43 But I feel like it's kind of staying right right there, which is what I was when I, as soon as he walked in, I'm like, I want to do it again. I want to see the leap from that. So yeah. So of course, for out of us, I had like a visual thing. Yeah. Right. So it's much easier because I know like vitality could be so subjective. Yeah. Exactly. You know, it's like, oh, yeah, am I sleeping better? Do I have more energy? Yeah. So, but I can definitely attest to, I notice like, oh yeah, am I sleeping better? Do I have more energy? Yeah, right. But I can definitely attest to, I notice all those things too.
Starting point is 00:30:08 Like I feel like my skin looks younger, I feel like sleep is better, I just feel like I have more consistent energy through the day, but of course I was there for the psoriasis. And so, and that of all the interventions that I've tried, nothing has progressed it this well, this fast. And then the other thing that I was telling you off air
Starting point is 00:30:31 that I find really interesting too is like, not only is it making it better visually, but one of the biggest challenges in anybody who has psoriasis can attest to this is like, just not itching it. Oh, right, yeah. And of course, every dermatology, but to don't itch it, try not to do that because then you're just scabbing it over
Starting point is 00:30:47 and you're making it worse. But anybody who's had this will tell you like, good luck. Yeah. You know, good. If you're laying in bed and your psoriasis itches, you ain't falling asleep. Like it's it will it'll drive you crazy. And I've had moments where I'm like,
Starting point is 00:31:01 I'm trying to discipline myself from not scratching. And I'm like, it's all around it. I'm like trying to touch it, but I'm like scratching the rest of my body, hoping it'll give me some relief. And it never does until you finally do. What this has done is it's, it's eliminated that like I don't even have a desire to itch it, which that makes me go like, oh, wow, that's that that means something internally has got to be happening that is not allowing it to flare up nearly as bad. So not only is it going away, but whatever mechanism was causing me to flare and then want to scratch.
Starting point is 00:31:31 Cause I used to tell the guys that I would know when I ate something that was an offender, because within one hour I would have to itch. So like I could be going the day, like I say, I'm fasted, which I would do this too, where I would fast every once in a while for a day. And obviously I'm good. And then I would start to introduce foods. And as long as I chose certain foods, I would be good.
Starting point is 00:31:50 And then I would eat something that I knew that was a potential offender. And then like clockwork within 45 minutes to an hour, I'm like wanting to itch. Where I've not been perfect at all with my diet since we've done this. And I don't have that at all, which is fascinating. And that, that to me is one of the take home messages.
Starting point is 00:32:07 It's building resiliency in your body because the reality is we have something like 86, 86,000 toxins in our environment now. And so the amount of toxins that we're exposed to on a daily basis is only increasing and it's not going to change. Let's be honest, the food supply, you guys have talked about this at length, right? The food, the, you know, the environment, plastics, micro toxins, like mold. So how do you build your body to be able to put up and have resiliency to deal with all this? Because a lot of people are just like, they're almost so fragile that they can't, they're like,
Starting point is 00:32:37 they have to eat such a small limited number of foods. They have to be so careful about how they live their life. And I'm like, man, you're not even like living life then anymore at that point. Right. So it's like how to, and that's why for me as a minimalist and also as like someone who kind of went, had a sensitive, some sensitivities before too. I was like, I want to live like as close to normal life as I can. It's like, what's going to have the most impact on my body? It's going to be this type of stuff where it's actually reprogramming your body.
Starting point is 00:33:02 Right. And that's kind of the idea with like the transplanting the new gut, the gut bacteria too. Yeah. Instead of a pro, because problem with probiotics is they're transitory. They don't, they don't actually repopulate and change your gut long term. So that's influenced your microbiome, but they don't, they don't populate.
Starting point is 00:33:15 No. And so that's why you have to transplant new gut bacteria. That's a gut transplant. You do that too. Yeah. We're going to have it ready. We have a third party, but we're manufacturing our own. How does that work?
Starting point is 00:33:24 It's just a pill. It's just, it's just, it ready. We have a third party, but we're manufacturing our own. How does that work? That's a good follow-up. It's just a pill. How does a transplant versus, like why does that transplant and other probiotic pills come from poop? Human. So it's specifically human bacteria. I've read all the studies, yeah,
Starting point is 00:33:37 but now it's actually something that's an option. Yeah, no, the issue was always accessibility, because you had to go to like, there's maybe like only a few clinics in the world and you had to do with the colonoscopy and like it's like how many people are really gonna do that, right? And now with the new technology,
Starting point is 00:33:51 you can lipophilize them. So basically like dry freeze them and then you can store it indefinitely, a shelf stable and then you just take, it's like a two week course that we're gonna have that's gonna be available. And how are you not gonna do it? Do we get to opt in on like some super athlete or?
Starting point is 00:34:02 Yeah, no, so there's actually very interesting there was There was a there was a So that's actually that's in our pipeline so our first generation fmt is it's what's called fecal microbial transplant We're gonna come up with a better name because I think that'll like, you know scare people probably like gut renewal or something Yeah,, you know. But it's funny you said that because there was a Taiwanese, like Olympic weightlifter champion, and she happened to also be a microbiologist.
Starting point is 00:34:33 So, and PhD scientist. So she like, I'm just like, who are these super humans? But basically, so she was like, I want to test my poop in microbiome. And then they found that she had this unique like this unique strain and they call it now It's published literature. It's called ol Olympic biphytobacterium 01 like olp01 is what they call it and basically when you transplant that into other people it increases cardiovascular fitness Like significantly and this is published data out there
Starting point is 00:35:01 So we're gonna make an athletic package where you do FMT, where you do FMT. Shut your face. Yeah, and follow statin' together and you increase standard strength and cardiovascular. Bro, you know what's gonna happen? They're gonna have pictures of the athletes they got the poop from.
Starting point is 00:35:13 Yeah. You're gonna look at the bottom and be like, oh, what? Yeah, three times Mr. Olympia? I'll take that one. Overlooking back legs. Yeah. Like that picture from one of the toilet.
Starting point is 00:35:22 Wow, that dude looks awesome. I want his poop. How do you not get pathogens, right? Cause like, you know, everybody knows you don't eat poop. Yeah, no, picture from one of the toilet. Wow, that dude looks awesome. I want his poop. How do you not get pathogens, right? Cause like, you know, everybody knows you don't eat poop. Yeah, no, no. There's a whole process. So Dr. Caroline Ganibis, she's our human microbiome scientist.
Starting point is 00:35:33 So she has a whole IP, like proprietary process on how to donor select, how to capsulate, how to store them, everything like A to Z in terms of manufacturing. The donor selection cracks me up. So there's literally people who work for these companies. Yeah, they do full time poop donation. There are people in the U.S. who are doing that now.
Starting point is 00:35:49 Well, they get pretty decent. They get, I think they can make like sick figures. So many opportunities out there. Yeah. We're flushing the job. We're doing a good job for it. That's insane. OK, so back to Adam.
Starting point is 00:36:02 So he was also, you also gave him a peptide called GHK. Yeah, but why we're talking about mine and the psoriasis for the audience so they can hear you because you've explained to me multiple times and I don't even want to try an attempt, but explain the mechanism that's happening specifically for me and psoriasis, right? I have an autoimmune, it's tacked my body, you put these stem cells in me. What is happening that's causing it to get better? Why might it kind of plateau and why I might need more like kind of explain what what's happening? Yeah, so autoimmunity between different autoimmune conditions, there's probably more similarities and there is differences. And I think that's where a lot of people get kind of choked up is like, they go to their rheumatologist or they go to their specialist and then they're treating because they're so siloed, right? They're kind of like, it depends on what specialist you go to like for multiple sclerosis
Starting point is 00:36:46 You'll go to a neurologist for psoriasis you go dermatologist for like lupus or rheumatoid arthritis You'll go to rheumatologists, but the reality is all these different autoimmune conditions actually have a lot of similarities So and that's what we're trying to treat and that's why a lot of people are like how are you treating all these different conditions? It's not because it's not because I'm like, you know I have the knowledge set of all these different specialists. It's because I'm thinking differently from them. And what we're looking at is, okay, you have immune dysfunction. So where is this immune dysfunction coming from? The two biggest things are the thymus gland and then the gut. So because the gut is where most of your immune
Starting point is 00:37:20 system is stored. And then the thymus gland is kind of where your immune system goes to get trained. So that's where the T cells learn how to target. But there's something called T regulatory cells, T reg. And so T reg cells are so important in your body for maintaining what's called immunotolerance, or immunohomostasis, let's call it, to prevent your body from attacking itself. And so what happens is T regs become dysfunctional
Starting point is 00:37:43 in autoimmune conditions, and then they start becoming, obviously,-starking other kind of things depending on what vulnerabilities and genetics you have like for you Are you obviously develop psoriasis, but other people may develop lupus? and so and one of the really interesting things now we In the just in the past two years and have come out is muscle is very protective for auto immunity because of Treg cells muscle is very protective for autoimmunity because of T reg cells. So it up regulates T reg cells and their function. So that's part of the reason why putting on muscle and not just training
Starting point is 00:38:10 cardio is so important for patients with autoimmune conditions. But a lot of times autoimmune condition patients are in this kind of vicious cycle where they don't have energy, you know, they can't, because they're in pain or whatever. When they lose muscle gets worse. Exactly. They're stuck. And that's what we do.
Starting point is 00:38:23 We have to break them out of that cycle and then it's so life changing for them. So in your case, the reason why it worked and the reason why it's helping is because it's reducing inflammation in the gut, it's reducing inflammation in the thymus, it's promoting your immune system to work better. And so that's why you're reducing this chronic inflammation. And then we add those bioregulators on those peptides to promote function of the thymus gland. That's why you're on thymus and alpha one
Starting point is 00:38:46 and all the other stuff to kind of work synergistically. And like the last kind of missing piece is the actual microbes. And that's why transplanting new gut bacteria will be great for you because you're basically helping to replenish the gut bacteria. Because the gut really has like two really broad issues. One is like leaky gut or chronic inflammation,
Starting point is 00:39:04 intestinal permeability. And then the other is dysbiosis, which is an imbalance in the bacteria. They're both connected, right? Exactly. And so where the IV stem cells is treating one, but transplanting the new gut bacteria is kind of the other piece. Well, so I read, read something that said that 60% of people that suffer from autoimmune disorders also had childhood trauma. Yeah.
Starting point is 00:39:26 Do you think that's just correlation or do you think there's something there? No, I, I, so we're doing this procedure called the vagus nerve and we're doing it for so many patients with chronic pain, autoimmune conditions. It started out, so, So explain the biggest thing first. Yeah, I'll give a little bit of history of it. Because so there's something called a stela ganglion block that's been around for maybe 20 years. A stela ganglion block has been done by many doctors
Starting point is 00:39:49 and it's essentially an injection into the stela ganglion in the neck area, which feeds into your sympathetic nervous system, which is kind of your fight or flight. So if you're fighting- And this is for PTSD people that have been doing this. Exactly, yeah. So it's called an SGB block.
Starting point is 00:40:01 It's been around for a long time. And so what we did was we were like, okay, that's great. But is there something we can do that would help this to last longer? And so there's a doctor, Dr. Jonathan Koo, who I work with in the States and Dr. Matt Cook, who kind of were looking at Vegas nerve. And so that's where I learned that, hey, if you intervene on the Vegas nerve and the Steli ganglion together, now you're not only innovating on the sympathetic nervous system, the vagus nerve feeds into the parasympathetic nervous system. Parasympathetic is relaxed or digest.
Starting point is 00:40:32 So it's kind of the opposite of the sympathetic. And a lot of people in modern day, especially with trauma, are in sympathetic overdrive. So they're in this hyper aroused state. They're irritable. They're anxious. Some of them can't, obviously sleep issues, all sorts of stuff. And then you can only imagine what effect that has on your body over years. If you're in this hyper arous state, what's that going to do
Starting point is 00:40:53 to your immune system? And we know now that the nervous system and the immune system are connected. And so what we do, instead of just injecting anesthetic, which just suppresses your sympathetic tone for three months, which is great. I mean, it's still helpful, but it's pretty temporary. So what we do is we inject peptides and exosomes into the vagus nerve, so that helps to modulate or restore vagus nerve dysfunction and helps your parasympathetic relaxation system. And then we inject peptides and anesthetic into the stelliganglion. So that helps to not only suppress it, but has a long-term reprogramming effect. Yeah, so and the vagus nerve is basically the highway
Starting point is 00:41:29 between the brain and the gut. That's how it's communicating. Yes, exactly. So that's why I've had patients with like gastroparesis, chronic gut issues, all sorts of stuff get better with the vagal nerve. The most interesting, I mean, aside from like anxiety and trauma, I've had patients like with chronic pain
Starting point is 00:41:43 after the vagus nerve injection, they're like, my pain's gone. I'm like, really? That's like, it wasn't the reason I was doing it. It's just, it's so interesting though, there's obviously this connection between inflammation and, and your, and the vagus nerve. It's so weird that you brought this up because I literally have been reading about polyvagal theory, uh, because I, because I have these gut issues that just keep popping up and I'll
Starting point is 00:42:00 treat them, they'll go away and they just keep popping up. And I'm reading about polyvagal theory and how the vagus nerve is affecting all that. Cause there's rest digest, there's fight or flight, but there's also something called freeze and fawn. That's the other one that they've identified, which some people when they, when they're in that state, they don't fight or flight, they freeze. They just, they don't do anything.
Starting point is 00:42:18 Yeah, right. And I've had many, I've had many patients with like panic attacks. I think we're talking about like, I had a pro golfer, his name's Matt Wolf, he wrote us a review so I can talk about him, but he has one of the fastest golf swings in the world and he was having performance anxiety when he was playing away games.
Starting point is 00:42:34 And so we did the Vegas nerve treatment for him and now he's playing like the best golf he's played in years. So, because it's just, you're less arousable, right? And so I had it done on myself. I'm not like a super anxious person, but I have a lot of stress in my life just like everyone does. And so it just, it kind of chills you out a little bit. That's why, I mean, that's what I did for my wife too,
Starting point is 00:42:53 it's chill her out a little bit. Yeah. Hey honey, do this smart. So let me ask you this. Okay, so here's my questions with that. If you did the treatment with the Vegas nerve and you're not as aroused, does that mean you're not gonna be able to get as aroused?
Starting point is 00:43:05 Like I can't go lift weights heavy, I can't get heavy. No, no, exactly. And you guys know this, because you guys are so familiar with peptides. Peptides only kind of work where they need to and what they need, and same thing with exosomes. It's all about, they're not gonna do anything
Starting point is 00:43:15 if there's nothing to do. It's not forcing something. It's not forcing something, exactly. And so that's why the beauty, that's why I like this whole regenerative medicine field, because it's all about kind of reprogramming or rebooting or trying to take the body into a previous state, right? And that's kind of the whole idea of what we're trying to do.
Starting point is 00:43:30 Now, what peptide would you inject into the patient? So I use BPC 157 GHK and then also TB4 or TB500. So those are mixed. Cause they kind of have synergistic effects in terms of cellular signaling. Because they work different pathways and work together. They have a really nice way to kind of restore function to dysfunctional nerves and to dysfunctional soft tissue
Starting point is 00:43:53 and tendons. So I was using BPC 157 and thymus and beta 4, but just systemically, I didn't inject it in anywhere specifically, just under the skin. And I got leaner and stronger and had a different quality to the way my body looked. It just, it took a little time, but I started to notice that I just, like everything looked a little different. And I kept telling these guys, like, this is wild.
Starting point is 00:44:15 Well, yeah. And as you get older, because the peptides are naturally occurring in your body and a lot of them as you get older, decrease. And that's why the fall of statin, which I'm sure we'll talk about in a second, what we did with the gene therapy is basically just a delivery mechanism to restore your fall statin levels back to like when you were like 18. And that's all it's doing. It's a naturally occurring thing in your body.
Starting point is 00:44:32 And so we're going to make different gene therapy products. We're going to make one for BPC. We're going to make one for GHK. We're going to make one for DP4. We're going to do all of them. So that way you don't have to inject yourself every day. You just do one injection. You're good for it.
Starting point is 00:44:43 Fun fact on thymocenthalpha which you talked about that you gave a little bit to Adam, they put, they blocked the production of that during COVID. I don't know if anybody knew that. Did you know that? Awesome. The one thing that has been shown to be super effective in Russia, thymoline and thymocin alpha one. You can actually treat-
Starting point is 00:44:58 And then all of a sudden you couldn't get it. They stopped it. Of course you couldn't. Interesting. And you know, there was over, I talked about this during COVID was, there was over 40 randomized control trials on like intravenous stem cells and exosomes for COVID.
Starting point is 00:45:09 Yet not one media outlet ever talked about stem cells or exosomes to treat COVID. Like not only long COVID, but for acute COVID in the hospital. You could help so many people and exosomes are pretty inexpensive to manufacture and they could scale those, especially if the government was to subsidize it. We put them on ventilators. Wow. It's just, yeah, it's really. All right. So let me, so, uh, so the other thing too, Adam was using GHK.
Starting point is 00:45:30 That's another peptide that he's using. Yeah. Technically a bioregulator as well. So it is, because it, uh, bioregulators are basically something that helped to improve organ function too. Okay. So then they're not just acting on like signals in the, they're actually helping with the organ function.
Starting point is 00:45:44 Now GHK helps with the regeneration process of like the skin, hair follicles and all that stuff right? Yeah. Is that what's happening with that? And what's what is it? Isn't that isn't that in the cream and then also in the injectable? Yeah, yeah, copper peptide is I mean a lot of top a lot of companies now cosmetic companies are using copper peptide in there but the problem is the concentration is always so low. So I was using some on my head for hair growth because supposedly it grows and it made my hair darker. Interesting. Yeah. So I don't know if it's because of the copper or I don't know
Starting point is 00:46:14 what the deal is, but I noticed my hair was getting darker as a result. So I don't know, I'm asking you. No, no, I mean, the reason for graying hair, it's a lot like you need more copper. Yeah, yeah, exactly And then they've they've learned that this the cellular basis for it has to do with stem cells becoming in a senescent So certain stuff cells actually become senescent and then they and then they're the ones responsible for melanin production And then that's why your hair starts to gray. So if you can make those stem cells not be senescent anymore Then you can get rid of gray hair. So that's that's one of the things where one of the cell lines we're working on are, you know, that Yamanaka stem cell technology I was telling you about.
Starting point is 00:46:51 So we're going to differentiate them into hair dermal papillae cells. So basically the progenitor cells are going to regrow new hair follicles. So we're going to have high PN, for hair loss. Yeah. So we're, so I'm actually, that's the project where we're, Now would you have to inject that locally? Like someone said, Yeah, but you would inject it just into the scalp and then you could regrow new hair wild. Okay. Look at Adam He's so excited fix the surprise So here's what I noticed up from everything. I I noticed a lot of my skin My skin seemed to feel a lot. It just felt more youthful in my wife has been even saying she's like man You're skin I and I didn't have bad skin before.
Starting point is 00:47:26 She always commented on my skin, but it looked a lot better. And then I noticed just, I would say nothing profound, but like a consistent 10 to 15% improvement in overall energy that I just have been feeling. I'm just feeling more, just almost like I was, like in my early thirties, it kind of felt like where I just got a little bit more energy throughout the day.
Starting point is 00:47:48 It was the big thing, but I had no major issues like Adam. So yeah, how's your, how's your strength? Has, have you seen changes in that yet? You know, I haven't been able to push myself super hard, but generally speaking, um, I am stronger like I would be if I was more on point. So I know how strong I can be when I'm hit on all cylinders and I know where my strength is when I'm under a lot of stress or whatever, like I would be if I was more on point. So I know how strong I can be when I'm hit on all cylinders and I know where my strength is when I'm under a lot of stress or whatever like I have been.
Starting point is 00:48:10 And my strength is like it is when I'm running on all cylinders even though right now I'm going through tremendous stress in my life. So that's something that I thought. I thought what I felt was even is was just as profound in this also. The neural drive you said. Yeah, what's interesting for me is so I'm like, probably the opposite of Sal right now,
Starting point is 00:48:27 like he's super consistent. He's always really, really consistent. As long as I've known, I've never seen him miss a week of working out where I've had many bouts of, since we've been on this podcast of weeks of not working out at all. And so I've been very inconsistent about my training. And, but I've been doing this for so long. I know what it feels like when I get back to being consistent, right? And I know those first few workouts, what a struggle it is and the recovery on it, how weak I feel. Even like, like, uh, workouts will even make me feel a little lightheaded and nauseous when you first start at the very beginning of getting back into your,
Starting point is 00:48:58 your, that was all like gone, which was really interesting to me. It's like what I know,, what kind of like the first workout of getting back into the swing of things was going to feel like I felt like amazing. I felt like I'd already been working out for like four weeks consistently. So that was really profound and interesting. And then I come running in here after a day that I would
Starting point is 00:49:17 reflect the first day that I did like inclined bench press. Again, a movement I've done a million times. One of the things I've never been good at, I've never been good at leg drive with the bench press. Just never been able to, like what they say, connect from your feet all the way up. And I've practiced the technique a thousand times and just have never felt like,
Starting point is 00:49:38 oh, I'm getting extra strength from my legs for the first time in my life. And it was literally the first time I just get out of there and I'm not even like trying any hard. I'm not even going like, oh, this is supposed to help this. I just do it. I'm like, whoa, I can feel like I'm connected to my feet all the way down.
Starting point is 00:49:54 And then I came out to him and I was like, hey, did Dr. Kahn say this was supposed to do something with neural drive or something like that? And then I shared with him like, dude, this is what I feel. And I've never felt that before. I was really fascinated by that. Like that was interesting. Yeah.
Starting point is 00:50:06 The neurological drive. That's why a lot of that's the fault. That's the fault. So the hockey players, football players, and then, uh, Devon Lariat, probably the guy who benefited the most from that world champion arm wrestler. And he actually made a post. He thanked me on stage when he won. He's like, thank you, Dr.
Starting point is 00:50:21 God, which was, I was like, okay, wow. Because he, because he, uh, he won number one again, because, and he's 48. Um, and he said the follow stat and made him feel like he was 20 years younger. So that's, so that's what you're reminding me of working out when I was 17, 18 years old. Yeah. It's like, cause that neurological firing and that that's what, that's my favorite part too.
Starting point is 00:50:42 Cause I'm like, you know, I'm a stress. I'm traveling. I'm doing a lot of things and like it's cool that I can just jump into a gym and not feel like, you know, I'm a stress, I'm traveling, I'm doing a lot of things and like it's cool that I can just jump into a gym and not feel like, you know, I've been out of here for like weeks or something. It's different than like a testosterone. No, exactly. Yeah. Yeah.
Starting point is 00:50:53 It's nothing like that. Yeah. It was like, for me, it was more, I felt kind of normal in terms of like just a little more energetic, I would say, but you know, once I got into actually exercising, it was like, this is weird. I feel like I could do probably like five more reps. Right. Normally right here I would say, but you know, once I got into actually exercising, it was like, this is weird. I feel like I could do probably like five more reps. We were normally right here. I would stop. And it just became one of those things where I was experimenting with other exercises. It was the same across the board.
Starting point is 00:51:14 It was at least like a 10 to 20 pound increase on most the list. I just normally, which is a lot for an experienced lifter, right? Yeah. Oh, that's you. So fall of statin is, uh, that is inversely related with myostatin. That's right. Yeah. So that's the Oh, that's you. So fallostatin is, that is inversely related with myostatin. That's right, yeah. So that's the main, is that the main mechanism of action? It's reducing your myostatin,
Starting point is 00:51:31 which is a muscle growth limiter. Yes. That's the main for mechanistic energy, I mean, strength benefits. Okay. But so that, and that's why the bodybuilding community knows about fallostatin.
Starting point is 00:51:42 Like they've heard a lot of them have been experimenting with it and trying it for years and years. But the problem with the peptide that you order off wherever it's, it's just a peptide. It's not a gene therapy. And so the half life of fall statin is 90 minutes. You have to inject it like three times a day or like 20 times, 10 times a day and wake up in the middle of the night and like for it, for you to replicate what the gene therapy is doing,
Starting point is 00:52:01 which is keeping your fall statin levels at steady level. And now yours is essentially just always, now it's just always in us. Yeah, yeah, exactly. So the cool thing about this gene therapy, because when people think gene therapy, they're like, are you editing my genome? That's a CRISPR, right?
Starting point is 00:52:14 CRISPR is what actually editing your genome. You can have off-site targets, there's risk with that. But this is a gene therapy because we're inserting a foreign plasmid, but it's only staying in that local, so we inject you guys like in your arms, right? So it's only staying in that local site So the only the local cells are transformed with that plasmid vector and then it's just producing more of the fall statin
Starting point is 00:52:33 Which then goes systemic exactly so my left shoulder is not gonna be bigger. No exactly Yeah, that's what that's what Mikhail I thought she's like it's my arm gonna get bigger I know no and is there any value of Doing more of that or more frequently or is it like? It saturates. So that's why I gave you guys two dosages because after that it doesn't seem to,
Starting point is 00:52:51 it doesn't do anything more. Yeah, you can inject, I've tried it on myself. I've done like four dosages. What's the upper limit? My kind of guy. That's what I would do if I was a doctor. I mean, what you explained I think is one of the, I think probably the simplest way for me to explain it is someone is, especially being that we're in our, in our 40s now,
Starting point is 00:53:09 there's a clear difference to how I feel like when I'm deconditioned and I get back and get back to the gym versus when I was 20 years old and like when I was 20, I could have had been off for three months. I could have had terrible sleep that before eating like terrible, get in the gym, do my thing. And there's, I don't have any awful feelings. It's just, oh, I'm getting back in. So I'm weaker. So what? I don't, I don't think about, oh my God, this is rough in your 40s. One of your off for that period of time to get back in. And there's always this like ramping up of like, Oh man, this is, and it didn't feel that way at all. It felt like I was 20 again, getting back to this, which is, boy,
Starting point is 00:53:42 I could see the value of that for someone who's just like really starting. I know we again, getting back to this, which is boy, I could see the value of that for someone who's just like really starting. I know we all, because we would consider ourselves advanced experience lifters, we're looking for the 10, 15% gains. But I mean, I could imagine somebody who's in their forties or fifties who hasn't been lifting for a really long time, the feeling of how much that's kind of compliance. That's that.
Starting point is 00:54:03 And that's what I really believe because imagine you just get more better feedback because a lot of people have a hard time time, the feeling and how much that's kind of. It'll help with compliance. That's what I really believe, because imagine you just get more better feedback, because a lot of people have a hard time sticking to the gym because they're like, I'm not really seeing the results. And because this will just, it makes the results come that much faster and you feel better when you recover. Yeah, so here's another, I mean, this is all subjective, but you know, and people,
Starting point is 00:54:20 this is gonna be hard to explain for people who don't exercise consistently for years and years and years, but there's a, there's a, once I hit my forties, I just noticed my skin looked a little different as I got really lean. Like I would see a little bit of wrinkling in certain areas of me, maybe the gut or whatever. And you see this with older athletes, they get really shredded. The skin doesn't look the same.
Starting point is 00:54:39 Slowly what's happened to me is, and I said this before with my skin, it's looking like younger. It's really weird. I have the look and I told these guys it's starting to me is and I said this before with my skin. It's looking like younger. It's really weird I have the look and I told these guys it's starting to look the way that it used to which it wasn't bad at all But it's just starting to look a lot different as we continue, which is really weird to me So it's all making sense now. Yeah, no exactly and that's just because of the Immunomodulation effect because of inflammation, which is one of the obviously drivers of skin and muscle aging. But wait till we get our copper peptide gene therapy.
Starting point is 00:55:09 So that'll be available next year. So we guys can do that. And the gene therapy will keep your copper levels back to restoring them for 18 to 24 months. And copper is obviously stimulates collagen production, keeps your skin youthful. I think that will be our biggest product just because cosmetics is cosmetics. And you'll notice that. Yeah, even the copper peptide, you can get copper peptide GHK topical and you get a good brand, even noticed within like two times, like two days, you can see a
Starting point is 00:55:35 difference. Yeah, yeah. Well, that's one of the, I mean, I think you're, was it your wife? No, your wife who did the facial. Yeah. Yeah. And then, yeah, we gave her the copper peptide cream afterwards. Yeah. Are you starting to piece together from this podcast? How often Sal tells us about how good he looks. Tell the guys, tell the guys. You know what it is? I talk a lot about little things. I notice they make fun of me. You feel everything. You notice everything. I just pay attention.
Starting point is 00:56:02 It's so subtle. It's so subtle things. It's weird. My clothes just come off. Face that way. I was just looking at myself in the mirror and I couldn't help notice. Oh God. Well, what I noticed, okay, was like, honestly it was really weird
Starting point is 00:56:17 because one of my food insensitivities that were across the board was just like completely offensive. How did you, how did you test? Did you? So I went through this whole protocol. Uh, it was like a three month protocol, actually six months even, um, but went through elimination diets and have gone through this whole process for, um, trying to target and figure out like, cause I have like really bad acid reflux.
Starting point is 00:56:39 And this has just been a chronic problem of mine since I can even remember and would interrupt sleep. And then again, it's this vicious cycle, you don't get sleep and then I'm just constantly inflamed. Not even realizing how inflamed my whole body is all the time. Like, so that was the other things people are noticing too. It's like, oh, your face looks leaner. I think it's just the inflammation.
Starting point is 00:56:59 Levels have just gone down dramatically. But it, like, absolved one of my food intolerances, like dairy in general, I can eat it, I can drink it, I can, and I was like, really slow, cautious, you know, kind of going in and then went full ham, you know, and had a slice of cheesecake. So mimolets, one of my favorite, I ate like a like a ton of it like and anyways, I'm a little crazy but I still do you have like so I still react a bit to Gluten and some some bits of like, you know wheat and and grains and whatnot So that was one of those things that's interesting that like that one it seems to be like completely non-offensive anymore
Starting point is 00:57:44 But now you know, I'm still kind of working my way through that one. But that was the progress to me. That was huge because I was like so depressed when I got the results. The cheese was like killing me. I mean, that's life changing, obviously. It changes the quality of life. Why aren't these like just so why aren't they widely available? Like why, why is it so hard to find this kind of stuff?
Starting point is 00:58:03 Yeah. I mean, I think one person who has gone in depth through this is John Abraham, Abrahamson. He wrote a book called Sickening and he was on Lex Friedman's podcast. And he's a great guy who he basically explains how Big Pharma has what's called a revolving door with the regulatory bodies.
Starting point is 00:58:20 Yes, they do. So you know what that means. People work in the FDA. We used to work for Pfizer or whatever, and they go back to the FDA, and they're promises massive salaries. It's very interesting. Yeah, so, and he's obviously the expert on that,
Starting point is 00:58:33 but the gist of it is that these therapies are gonna take away from hospitals, right? Orthopedic surgeries, which are a huge revenue generator, and that's what we treat a lot of. And, you know, I have many pro athletes who come to me for that. And there's a reason, right? Because they're orthopedic surgeon on their team and the institutions that represent
Starting point is 00:58:50 these teams are all in the same, they're all in the same boat together. And they all just want to kind of keep that narrative going, which is that surgery is the only option or. Coupils are the only option. I'm not saying this works for everyone, for everything. It's just something that should be offered and have a specialist consult to see if maybe you're a candidate for it. Yeah, because right now to see you,
Starting point is 00:59:09 someone would have to see you, they can't see you in the States, right? No, it's FDA banned peptides now, right? So even with a big part of my practice is peptides and I can't even prescribe them anymore. So I'm essentially like barred, like it just doesn't make sense for me to work here or in Canada anymore because they're kind of the same health Canada and
Starting point is 00:59:27 FDA. So we saw you in Mexico. So you're there. Yeah. And then Dubai and then Switzerland and London actually, because of Brexit, they're, they're, they're, they're actually having a, you know, some changes in their regulatory stuff. What have you noticed the biggest, have the biggest impact on the people you work with? Is it always a stem cell? I mean, I think from a, as I'm an interventional list, interventional doctor, I inject people, I do interventions to help people. I'm an interventional pain doctor, sports medicine by training. And so my reason I went into interventional medicine is because I really
Starting point is 01:00:01 find it rewarding when I get to actually do something with my hands and make a big difference in people's lives. And so the Vegas nerve injection I think has been the most rewarding because it's immediate and whereas stem cells sometimes can take months and months and I'm just an inpatient person so I'm like, come on, I want to see, but it is amazing to see people's lives change with that. But I've literally had people's lives change with an injection that takes five to 10 minutes and they're no longer suicidal. I had a guy who's a special forces operative.
Starting point is 01:00:29 He trained the guy who has the longest sniper shot in the world. And so it's like 3.2 kilometers, something crazy. And he's like he's mentor. And so this guy himself, it's obviously elite level special forces guy. And he had terrible PTSD. He's in his forties, Canada being the place where it is, failed the medications, they're like, well, I guess you can go do medically assisted suicide
Starting point is 01:00:50 or made as it's called, medically assisted dying. So crazy. I can't believe they do that, but anyway. I know, and a veteran who sacrificed, and you know, health. What's crazy is they've now included people with mental health issues in that category. Yeah.
Starting point is 01:01:01 So being suicidal qualifies you now to have them kill you. It's so crazy. And so that's, you know, for me, I was kind of like, this is really disheartening. Like, is there something I can do? And so that's how I got into this whole mental health stuff was, because I'm an interventional doctor and I'm not a psychiatrist, but I was like interventionally trained. So that's where my head went was a Vegas nerve and, you know, exosomes, peptide, all this stuff.
Starting point is 01:01:23 So that's, that's what we did for him. And literally 10 minutes later, he was in a parking lot because the guy who brought him the health coach, he told me he was crying and he's like, this is the first time I've had relief in years. Really? 10 minutes later.
Starting point is 01:01:33 Is it a painful injection? Cause it's a nerve? Is that a nerve? No, it's not like peripheral nerves. It's not like you're gonna, it's not like that. It's just, sometimes you might get a little bit of pain into your shoulder, but most of the time people are like, that was barely anything.
Starting point is 01:01:44 It's like a little pinch. You feel it and then it it's done like it literally takes five minutes. It's so crazy I'm literally reading all about this right now because how important is the Vegas nerf? Well, I mean when I'm reading about this and people can look this up I'm not not even close to like privy on it, but so far what I've read is I mean you when you develop trauma Whether it's one big trauma or lots of little traumas This nerve. I mean, it basically operates under your awareness. So it's like an automatic thing that's happening
Starting point is 01:02:12 in your brain, your body. And by the time you're aware of it, it's too late. Oh, shit, I'm anxious. There it is. Now that's it. I can't do anything about it. Exactly. Chronic Vegas nerve dysfunction is so common.
Starting point is 01:02:21 And after COVID, it's a long COVID, it's a common thing with that too. So now even more people have it. Wow. Wow. That's, this is crazy. Okay. So it's gonna be interesting. I mean, I'm really curious to try. I want to do that. If it's connected to like I went back to my sister and I both have these, she has endometriosis. So that's what she suffers from. And it's interesting that we both had this, got obviously similar childhood, right? And so yet, very, very different diets and everything else lifestyle while it's the only thing we share in common is the household that we grew up in.
Starting point is 01:02:52 And so there's a part of me that wonders and then I wonder because I feel like, man, I don't have any stress. I don't feel like I have anxiety. But is that just because I've adapted so well, you're disconnected. And it's subconsciously, your nervous system remembers, right? Like, so is it and it holds it, it holds it. That. And it's subconsciously. Your nervous system remembers. Right. Like, so is it, is it, you know, and it holds it, it holds it. Right. That's why it's operating at a different level.
Starting point is 01:03:09 That's why the release can be so life changing for people. I can't help share this story because it just, it was like two weeks ago. I had this girl, she's, she's like 23, 24. She's doing her PhD and she had to stop doing her PhD because of severe anxiety. And she was getting panic attacks and she came to a point where she was suicidal. So she was, she was literally before she came to see me. She was at a hospital admitted for suicidal ideation. And so I was like, man, I don't know if I'm going to be able to really help her.
Starting point is 01:03:33 Cause it's so severe. And then 10 minutes after the injection, she started crying and saying that I feel relief for the first time in two years. Cause it was just on and it was just hyper arousal. It was just on. And this just helps to stop that arousal. It's unbelievable. Some people aren't that fast.
Starting point is 01:03:50 Obviously, some people may take a few weeks because it's a little more low grade. But for people who are acutely PTSD, trauma, have that nervous system dysfunction, man, it's unbelievable. Now, do you think there's any, because are you, we talked to them when you're at my house, or we were talking about like ketamine therapy and psilocybin. Yeah, do you think there's any, cause are you, we talked to think when you're at my house, or we were talking about like
Starting point is 01:04:05 a ketamine therapy and psilocybin. Yeah, we combine, it kind of gets your body ready for that. Right. Because if you're Vegas, and if you're in this hyper route state, it's going to be harder for you to do those assisted therapies because harder for you to go into that relaxed conscious, you know, subconscious state. So what we recommend is we do this and then we send them off
Starting point is 01:04:21 for psilocybin assisted or whatever. So here's the analogy that I would use around this. Again, I've been reading a lot about this, but when we train people and if they have a movement pattern issue, and let's say there's a muscle that is, it's tight. It's tight because a central nervous system identifies that this particular joint or movement pattern feels unsafe. And so what we would do as a trainer is we would do what's called correctional exercise. Unfortunately, sometimes they can't even do the movement properly because their CNS doesn't feel safe. So what we'll do is foam roll or
Starting point is 01:04:52 deep tissue massage, press on the muscle. And what that does is it literally temporarily turns that CNS signal off, gets that muscle to kind of chill. Then we can do the correctional exercise and develop a new recruitment pattern. So the analogy here would be like Vegas nerve, get that to chill out for a second, then do the therapy so that we can rewire some of these problems. Exactly, rewire the nervous system. It's a great analogy and that's exactly what we're doing. You can use that if you want.
Starting point is 01:05:16 I love it. Definitely got to take that. Well, really, it's not necessary, I mean, and just for the nerves that we'll get on here and try and correct that, it's not that it's turning it off. It's calming it down. Yes. Because they're still a central nervous system connection. Correct. It's overactive, which is why.
Starting point is 01:05:30 That's why when you have a knot, it's modulating. Right, right, right. And that's the word I always like to use, modulated, right? That's the theme of this discussion, right? Immunomodulation for your immune system, nervous system modulation, right? It's all about reprogramming. Okay. So we should see more benefits over the next few months then,
Starting point is 01:05:47 since we haven't even... That's exciting. Yeah, yeah, for sure. And the benefits with recovery, sleep, and all that stuff can be more profound after a few months. Wow. I'm excited. Would you say the poop pills are ready again?
Starting point is 01:05:58 They should be ready by April. I should call it that. I want to buy April. Yeah. You guys sent some of this. Got renewal. Yeah, oh yeah, no, for sure. We all want to get you guys.
Starting point is 01:06:04 Yeah, yeah, no. I don't know. You guys, when you guys watch that, I look like Athlete's poop. Yeah, you guys sent some renewal. Yeah. Oh, yeah. Oh, yeah. No, they're dry I guess you could let it. I already have a hard time taking pills. You might have a real hard time taking pills. Worse than fish burps after. Yeah. Do you change supplements? But think about the, there's a company that just got approved to do fast track FDA approval in the States.
Starting point is 01:06:34 So they are becoming more accessible. So I had, do you guys know Nick Mitchell? The ultimate performance guy, UP? He was a good friends with Paul Quinn. Oh yeah. I've seen his stuff. He has a theory that he thinks the pills, those FMT pills will be the most prescribed medicine
Starting point is 01:06:48 in 10 years. Wow. And I agree with him. I could see that because we'll have so many different versions by then and there'll be so many different uses for it. And we all know the gut is where a lot of problems start, right?
Starting point is 01:06:59 Do you have a lot of professional athletes that you just can't talk about because they come see you and they can't know what they're saying? Yeah, I mean, I think it's just so cool to be able to get these guys back to their elite top level. It's fun working with them too. It's like it's completely different from working with someone, you know, who's like PTSD trauma and working with like an elite high level athlete. Totally different. Totally different. Totally different. But I like both are to me are equally rewarding because it's just helping getting back to people what they want to do. Yeah.
Starting point is 01:07:25 Yeah. Now at the moment, these treatments unfortunately are not inexpensive. They're up there in terms of the treatments. But do you see in the future at some point this being something that? Even it's cheaper than it was last year. So I mean, that's progress, right? And that's going to continue to be getting cheaper because once we have the second generation one, then all of a sudden we have the second generation one.
Starting point is 01:07:43 That's for the more, let's say, like celebrity elite clientele. And then we'll have the regular one that are still effective for many things and will be cheaper because the one that's more expensive will be able to allow us to drop the price for the old one. I always, I love the, I mean, I love what Elon did with Tesla back in the day
Starting point is 01:08:00 because he had that vision. Unfortunately, I don't know what he's doing now, but back in 2010, he had the vision to be like, okay, if I want to get a mainstream car to everyone, we have to have a very expensive car that maybe isn't that great, but we have to give it to celebrities and famous people first,
Starting point is 01:08:15 because that's the only way it's gonna become mainstream. So he gave it to Leonardo DiCaprio, Tom Cruise. He would just be like, here, take the car, try it out, let me know what you think. And it wasn't that great, it was just a bunch of lithium-ion batteries car, try it out. Let me know what you think. And like, you know, it wasn't that great. It was like just a bunch of lithium ion batteries like taped together and like it didn't go that far. But it was enough and he was able to sell enough
Starting point is 01:08:31 to kind of fund the next iteration, which was like the Model X or sorry, the Model S, the Roadster than the Model S than the Model X. But those were all like 150, $2,000 cars. Yeah, now you can go get one for 30 grand. Exactly. So this is the exact same analogy because it's many the manufacturing process of growing stem
Starting point is 01:08:45 cells and gene therapies, all this stuff is improving and the investment into aging especially is massive. All the rich people, they all want to live longer, right? And they all, they all putting a huge investment into this. And like I said earlier, if we can solve aging, we can solve a lot of these chronic diseases and it'll just mean more accessibility. So to me, this is actually, a lot of people may criticize, oh, he only treats rich people.
Starting point is 01:09:08 I would actually say he's democratizing health for everyone because eventually these treatments will be affordable for everyone and they will be so effective for so many different chronic diseases. So that's the future I see where these treatments become cheaper and more accessible. There's always some dummy that will say that right now,
Starting point is 01:09:22 but that's just how, that's just the process. That's everything. Look at electronics, remember flat screen. Yeah exactly Plasma TVs were like yeah, yeah, yeah, and now everyone's got four in their house. So relax It's just that's part of the process. So, you know, we this is now the second time We've had you and I feel like the entire first time and so far this time So it's over over an hour. We take advantage of your brain and we just ask all these questions. I actually want to know a little more on the personal side of like, how does,
Starting point is 01:09:51 how does a father or husband balance his life when you have something that you're so passionate about right now that is so cutting edge, so important, right? So I think society, what we're doing, how do you find the time the time to be to be dad and do you wrestle with that at all? Yeah, I'm I'm very fortunate because my wife is like super super supportive and she I mean you guys met her and she's And she's also she kind of gets a bigger picture. She's she's kind of Like okay, we're sacrificing but this is because it's for the greater good And it's because we're trying to actually make it. And she knows, like I'm so, I mean, I know it sounds a little grandiose, but like,
Starting point is 01:10:29 I mean, I think it can benefit all of humanity. Like in that sense that if we pushed these fields, these therapies forward, it can be something that can benefit everyone across the globe. Because let's be honest, there's a lot of people suffering and there's so many people with chronic illnesses suffering and they have no hope. And with these gene therapies, what, and cell therapies, eventually we'll be able to help so many people who right now aren't getting help. And being able to make this more accessible to more part of the world, yes, it sucks in
Starting point is 01:10:54 terms of how much sacrifice there is from family and personal things. And even now, like we were talking about, I probably have to move and like it sucks. Like I'm going to have to leave Canada, but it's like, I'm doing it for something that mission is bigger than just me. You know what I mean? And I feel like there's so many people helping me now in this mission and so many bright people that I have like amazing scientists, like obviously the podcast, getting the word out there. And I feel like it would be, you know, it would be short sighted to just say,
Starting point is 01:11:19 Oh, well, I'm just going to, I just want to spend more family time. Like I obviously I do, but at the same time, it's like, I think this is why I'm here and I'm just trying to do my purpose. Right. So did she, when you guys first got together, did she know that she was signing up for that? Or is that something that you've had to communicate throughout the relationship? No, definitely.
Starting point is 01:11:36 I mean, I don't think anyone, I mean, maybe some people can, but like, I feel like when you're on this, there's no way you can predict that this path would have happened. I feel like for a lot of people who are, you know,ber successful or whatever like it's really hard to predict that like you Would how could you have known ten years ago? This is where you would be and it for me? It was like I was I always knew I I thought a little bit differently from most doctors, but I never thought I'd be like, you know like Tony Robbins for example like he's probably the most like Influential person in my life from like 18 or years old and like the fact that I got to treat him, like he's probably the most like influential person
Starting point is 01:12:05 in my life from like 18 or years old. And like the fact that I got to treat him and now he's we're friends kind of like, it's just so weird. It's like surreal for me. And it's just like, like, I love the guy, like I bet I can't, I can't fanboy him when I'm treating him. But like just like, just because of the stuff, like to me, I like, I've never,
Starting point is 01:12:20 I've never been into like celebrities so much, but like, like Tony to me is like such a genuine nice guy who tries to help people. And he always inspired me. And the fact that I was able to get shoulder better, helping with so many different things, and he's really thankful. Like it's just such a weird, but almost like this weird interconnected thing where I feel like, okay, now I'm helping the people who help me.
Starting point is 01:12:40 And I feel like I have the means to help more people, so why not try? So my wife is very, she's tired of me not being home, but she's supportive of it. I mean, is that what you say, that's the biggest challenge, or I don't even wanna say fight, because I'm not gonna assume that you guys fight over it, but would that be one of the most challenging things
Starting point is 01:13:01 that you guys have to deal with as a parent and as a husband? Yeah, no, for sure. It's, it's, so I think the other thing too, like, I don't want to, there's, there's, do you guys know Inky Johnson? He's a, do you know Eric Thomas? Yes. Motivational speaker.
Starting point is 01:13:15 Inky Johnson is another one, like that type of level. He has this really good saying. He's like public success, public success, but private failure. And that's a lot of people. A lot. And including like Mr. Richest's a lot of people. A lot. And including like Mr. Richest Man on Earth, right? Like Elon, like he has nine kids and like he can't, like he's into a fight with his ex-wife about seeing the kid.
Starting point is 01:13:32 Like I'm not, I don't know all the personal details, but the point is there's a demand is obviously struggling personally. And like I think you can be publicly successful, but if you don't have a good home life and family life, what's the point? So there has to come a point where if you know, if something I have to choose, like I would always choose family first,
Starting point is 01:13:49 but I'm not at that point. But let's just say if I got to a point where it's like, man, if you're traveling too much or way too much, you need to cut back, I would be like, okay. You would. I would. Yeah. I mean, I think what you just said, this is actually something that I share all the time with people that, because we've now had the opportunity to be even closer to a lot of famous, successful people is I think people would be surprised how many of those people have a very dysfunctional home life. Now on the outside, they're famous, they're in movies or this professional athlete, they've got millions and millions of dollars, but then their wife hates them,
Starting point is 01:14:24 their kids don't like them, and like we don't see a lot of that stuff. And yet we, we admire and we put these people on these pedestals all the time, but very few of them actually have that balance. And stress. And you know what? One of the ironies is for people who are health conscious, social connection and meaning and emotional like relationships are actually one of the best protectors for health. And this was shown in a study,
Starting point is 01:14:47 I think it's called the Rosetta effect because it's just, yeah, you know about it, yeah. I do, yeah, no talk about it, go ahead. Yeah, so basically these, this like Mediterranean community of like Italians, there were times, yeah. That basically, you know, smoked, didn't really exercise,
Starting point is 01:15:01 lived pretty poor lifestyles, but then they would get together like five days a week and hang out and play games and just like, just chill basically. And that had so many protective benefits for cardiovascular disease, stroke, cancer. So it's obviously we're social creatures and we're meant to bond and relate with one another and who better, obviously your family is the best people to bond with. And if you can't even have meaningful relationships with them, I think it questions like not only character, but really like your priorities, right?
Starting point is 01:15:25 And so, and that's the thing, that's the thing that bugs me about Brian Johnson, the guy who's spending $2 million a year on his body and like, you know, making a lot of headlines and going a lot of podcasts. But the man like, you know, he, I know, I know he's, he doesn't have the best relationships with people. You know what I mean?
Starting point is 01:15:39 And like, it's like, so what are you really doing? You're spending all this time on yourself and trying to live forever, but like no one likes you. So. I mean, I love that you bring that up because we talk're spending all this time on yourself and trying to live forever, but no one likes you. So... I mean, I love that you bring that up because we talk about that all the time on here about how important it is to have community and to work on the relationship.
Starting point is 01:15:54 That's a part of health. In fact, it's a massive part of health. The point of that study, you have people that drink, smoke, do all these other things that we know are really bad, but yet they can live longer lives just because they have... Poor relationship was shown in a Stanford study to affect your health as much as a pack of cigarettes today. Exactly.
Starting point is 01:16:12 Loneliness is a more predictor of mortality than, I believe, smoking a pack of cigarettes. Yes. So loneliness is on the rise, which is like, why are people becoming more lonely and such an interconnected world? This has actually been called the loneliness epidemic. Yeah.
Starting point is 01:16:26 And it's affecting everybody, including children. You know what it's affecting the most? Men. Married men. Yeah, married men are experiencing terrible loneliness at ridiculous levels. Kids though, for sure. Kids used to never be lonely. What's the theory on that?
Starting point is 01:16:40 Why? Why? Because guys don't go out and try to make friends. So it's just getting worse and worse. Whereas we used to be forced to meet people because of things we had to do. Now men are going to work coming home and that's it. And it's, so we already suffered from loneliness at higher rates, but now it's like through the roof.
Starting point is 01:16:54 Yeah. Arthur Brooks was telling me about that the other day before you came in, we, we were having a dad discussion about the things that like I was sharing with the guys what I'm most fearful of, of, you know, the challenge. And one of mine is just, I have this like overly sweet son. And he's just like, he's like, and he's so good that like, I just don't, I don't ever have to discipline him. And it's like, and here he's already four going on five years old.
Starting point is 01:17:17 And I'm like, man, I want him to be tough though. And I want him to have some resiliency and he has nowhere near the adversity I had growing up. Yeah. I know I don't want to put him through the same thing. And so I wrestle with that as a dad. I mean, is there anything right now with your kids' ages that you, uh, you wrestle with?
Starting point is 01:17:32 Yeah, no, same, same. And I've talked about it with a lot of my high net worth patients because they've gone through that struggle too. It's like, it's not normal to like, you know, drive a Tesla and like go on all these vacations and that's not a normal life, right? But my kids think that's a normal life. And, and I and and I grew up, I grew up from immigrant family poor as well and like, so it's like, how do I get them to have that perspective? The only solution I've seen is travel and and that's why I take them. Showing them. Exactly and I travel, I try to take them
Starting point is 01:17:57 as many places as I can, take them with me to different places and try to show them that there's obviously so much more in the world and people who unfortunately in their situations where they're born they may never have the same opportunity that we have. So you got to take it and then show them that we're so privileged and blessed and as it's on us it's our social responsibility I believe to be able to give back and that's what Charlie Munger unfortunately passed away recently. I don't know if you guys know much about him. I don't know if Munger just passed away. Yeah I don't know if you guys know much about him, but he- I don't know, Munger just passed away?
Starting point is 01:18:25 Yeah. When did he die? Just like last month. Oh, shit. I didn't know that. Yeah. And he was probably my favorite billionaire because he, you know, being friends with Warren Buffett, he obviously got a lot of notoriety too.
Starting point is 01:18:38 But he was one of the ones who really talked about this concept of social responsibility and like giving back. And he obviously like lived it, right? He gave back everything to charity and to other causes and that's the same philosophy I have is if we're privileged enough and we show our kids that this is what we're doing with it, your kids are gonna inevitably be more influenced by you. So yeah, yeah, I actually I'll show you off-air because I don't want to totally mess it up on air and I will promise the audience that hears this that we will post it and share it. But I just saw the coolest way to tell your kids about Santa Claus.
Starting point is 01:19:10 And it's along the lines of like that. If Santa exists or not, the kid asks, I'll share the story with you when we get off air right now, but it's, it's really cool because the lesson is teaching to give without expecting anything in return. And the way the dad teaches the son, uh, if there is a Santa or not is really cool. So I'll share that with you. It's a good deal. Dr. Conno is awesome talking to you again.
Starting point is 01:19:30 You've just totally sold me on coming back to see you. I wanna get the biggest nerve thing. That's what I wanna get for sure. Yeah, let's do it. I got some help with that. Good deal. We'll schedule another time to come see you, my friend. All right.
Starting point is 01:19:44 Thanks for coming on. Thank you for listening to Mind Pump. If'll schedule a little time to come see you, my friend. All right. Thanks for coming on. maps anabolic, maps performance, and maps aesthetic. Nine months of phased expert exercise programming designed by Sal Adam and Justin to systematically transform the way your body looks, feels, and performs. With detailed workout blueprints and over 200 videos, the RGB Superbundle is like having Sal Adam and Justin as your own personal trainers, but at a fraction of the price. The RGB Super Bundle has a full 30-day money-back guarantee, and you can get it now plus other
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