Mind Pump: Raw Fitness Truth - 2822: The Truth About Insulin Sensitivity & Muscle Growth

Episode Date: March 26, 2026

Only $99 (2 glucose biosensors, Nutrisense App to map glucose repsonse in real-time) Nutrisense.io/mindpump Exclusive offer for the Mindpump audience, including a $150 discount.    Most people think building muscle and burning fat comes down to calories, workouts, and discipline. But what if the real issue is something deeper? In this episode, we sit down with a Rhett Langley, specializing in metabolic health to break down why your body might not be responding , even when you're doing everything right. We cover: Why metabolism controls fat loss and muscle gain How blood sugar impacts cravings, energy, and performance The truth about insulin sensitivity and muscle growth Why strength training is one of the most powerful metabolic tools How sleep, stress, and lifestyle affect your results more than you think The real reason some people struggle to see progress If you feel stuck, frustrated, or like your body isn't responding… this episode will change how you look at fitness.   The Spring Bundle: Symmetry ($187), Prime ($107), Advanced Training Techniques Guide ($47) all for $147 (over 50% off) mapsmarch.com        Give your snack game a serious upgrade. Crisp Power Protein Pretzels deliver super crunchy and delicious snacks that are up to 28g of protein, low carb, zero sugar and high in fiber! Add this guilt-free snack to your pantry Go to www.crisppower.com/mindpump and use code mindpump for 10% off your order ⇨⇨go to www.crisppower.com/mindpump  use code mindpump for 10% off your order (00:00) Metabolic Health & Why It Matters (11:00) The Doctor's Personal Wake-Up Call (20:00) Stress, Blood Sugar & Daily Lifestyle Impact (30:00) Why Muscle Improves Insulin Sensitivity (40:00) Metabolic Dysfunction & Sexual Health (50:00) How CGMs Help Change Behavior (01:00:00) The Biggest Levers: Training & Nutrition (01:10:00) Why Strength Training Beats Cardio for Metabolism (01:20:00) Brain Health, Dementia & Blood Sugar (01:30:00) GLP-1s, Medications & Fat Loss (01:40:00) Supplements That Actually Work (01:50:00) How to Fix Your Metabolism Long-Term

If you want to pump your body and expand your mind, there's only one place to go. Mind Pump, Mind Pump with your hosts. Sal DeStefano, Adam Schaefer, and Justin Andrews. You just found the most downloaded Fitness Health and Entertainment Podcast. This is Mind Pump. Today we talk about the power of insulin sensitivity, how you can improve it for better muscle building and fat loss. This is with Dr. Rett Langley. by the way, this episode is brought to you by Nutrisense.

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Go check them out. Go to crisppower.com forward slash mind pump. The code Mind Pump will get you 10% off. Also, we have a brand new workout program bundle called the Spring Bundle. Map Symmetry, Maps Prime, and the Advanced Training Techniques Guide, altogether 147. Head over to MapsMarch.com. All right, real quick, if you love us like we love you, why not show up by rocking one of our shirts, hats, mugs, or training gear over at Mindpumpstor.com. I'm talking right now.

Hit pause. Head on over to MindPumpstor.com. That's it. Enjoy the rest of the show. Welcome to the show, Rhett. Thanks for having me. Yeah, so tell us a little bit about what you do, your background, so the audience can kind of know where you're coming from. Yeah, so primarily I run a clinic in Houston, Texas. It's called Thrive Medicine.

And we specialize in metabolic health, sexual health. You know, I'm boarded in anesthesia and pain medicine. That's my traditional training. Okay. And then I spent the last seven years after doctor training really learning how to actually, you know, make people well. Okay. Explain metabolic health and what that, because you hear that a lot now. Like this is like a big thing now in medicine or in treatment or in a wellness space.

Like what is that exactly? Yeah. So when you go on this crusade to try to help people and you look at, let's just say this large list of symptoms that people have, whether it's, you know, and I break it down into like two large factions, there's sick people and there's people with problems that may not be determined as sick by the medical community, right? So sick people could be like, hey, I have cancer, dementia, sexual dysfunction, cardiovascular disease. And then over here is this, you know, esoteric not otherwise specified. I have fatigue, brain fog. I have, you know, skin inflammation, sleep disorder, et cetera, mood liability. When you look at all of that stuff, really at the bottom of that rabbit hole is the term metabolic dysphalysis.

function, right? And real simple definition of that is the physiologic processes in the body are not functioning properly, right? And it starts with looking at glucose, looking at fat, and then that translates into worse things like cardiovascular disease, like we said, sexual dysfunction, issues with the brain, so on and so forth. So it's essentially the, you're looking at taking what you consume and turning it into energy in that process. Although I just simplified it. It's a very complex process. We're talking about the metabolism.

There's a lot of things that are happening. Yeah. Yeah. Okay. Yeah. I mean, if I said to you like, hey, food is fuel, you'd say, okay, cool, podcast, bro. Great. But essentially, you know, that's what it is.

We're talking about, like, exchanging oxygen to CO2, taking in stuff. You know, having your body utilize that. appropriately in making sure that that physiologic process is dialed in. How much can this really affect someone's ability to build muscle or burn body fat officially? I mean, in our experience training tons of people, I've experienced this where, you know, you've got them on a good diet, you're exercising correctly, and then their body's just not responding and it's not adding up.

and many times there's other root causes. So like how significantly can it impact that ability to build muscle or burn body fat? Yeah, I think it's a huge impact, right? So it has a very, very large impact. If you, and honestly, you know, bodybuilders get this, right? They utilize insulin also to put on muscle, right? And they also know, like I even saw, you know, of course, the algorithm has control of me, but I saw the other day one guy was touting, he's like, hey, if you're, if you're fat already

or if you can't see your abs, don't try to put on muscle. So they're already catching on to the fact that it's not just calories in, calories out. You know, how much we eat and what we eat is really, really important. But when we look at what's going on underneath the surface, it has a huge effect on our performance, whether we're putting on, holding onto fat or adding that to muscle, and then all the other problems that come from that process not being dialed in. Now, doesn't exercise applied appropriately in diet improve the metabolic health of somebody? Like, those are also methods that can help with that, right?

Yeah, 1,000 percent. I mean, even – so I would say, like, that's – I hate to get to the point, but that's the overarching theme, right? Lifestyle modification. And if you look at – so you're going to hear me talk about these studies a lot, but some of the really, really large behavioral modification studies, one of them was diabetes prevention program, the look-ahead trial, those were behavioral modification. Those studies were RCTs, right?

And we're talking 5,000 people showing that behavioral modification most likely beat out other interventions, right? And what was that? It was looking at calorie intake, looking at physical activity, right? And then the other major thing here, the major thing, especially when we're talking about CGMs or what we do in our clinic, is they had a structured program. So they put these people through a structured program, right? You just can't give someone data or tell them like, hey, eat more, move less. Like, cool.

You have to spend time with these people and teach them and, you know, modify that as you go along. So what made you move from, so were you an anesthesiologist or trained as one? Did you practice? No, yeah, yeah. No, I mean, I still do some anesthesia. Okay. So what made you move from there to this space? It's so different in the sense that, like, you know, in anesthesia, you're, you know,

you're titrating people's anesthesia, making sure everything's okay during surgery. That's what you do. Now you're like, cool, let's look at your whole life. Yeah. Let's look at your lifestyle. Let's look at your diet. Like, what made you move into that space? Was there something that happened?

Oftentimes I talk to doctors who do that. It's like they either had their own health issue or a family health issue. Right. Was it something like that? Yeah. I mean, you know, to answer the question first and then back up and tell the story, It was subtle, and I think people relate to this. I thought I was healthy and felt bad and didn't know that, right?

And, you know, maybe you guys can relate. I was like, I was 90s fit, bro, right? So I was, this was prior to my awakening where I thought I was doing a bunch of stuff. I was going to the gym twice a day, you know, and back in the day, maybe you can relate. It was Inno explode, muscle milk. Good time. Cell tech. Yeah, we're all the same.

age. I'm dating myself, right? Yeah, we're all the same age. You know, men's health magazine was my Bible. And, you know, at that time, don't judge me. This was like dial-up, so checking the sources was not a thing, right? So if men's health told me like, hey, tequila, tequila stimulates metabolism, I'm like, all right, cool, like, tequila, right?

You know, calming your nervous system or mental fitness was two drinks, lion bed, negative feedback loop right like you suck bro get better right that's how I was taught that's how we grew up yeah um and then you know choosing the wrong relationships right so it wasn't until and again you know let's just I'll stop joking just for a second so going through doctor school and doctors get hazed a lot a lot about like oh it's not

appropriate training or that's out of context and I will totally say on this podcast that there's an indoctrination in every professional school, right? However, doctor's school broke my ass to be a really, really badass doctor, right? Like, it will turn you into a warrior. And when you do procedural medicine, like anesthesia, you have to, you do one, you suck, you do 10,000, you're badass, right? I don't say that arrogantly, but, you know, back to the story, like, when I met my wife,

she was like, hey, you know, are those dark circles under your eyes? is that like a birth mark? And I was like, no, that's probably something else that's really, really bad, right? I was irritable, moody. And because of doctor's school, like, I knew how to sleep four hours and get it all done, right? Drink late at night to help myself go to sleep, wake up at six, I can handle it all. Right. So that was just a wake up call, right?

I was like, okay, I feel good. But something else is going on. I was hitting the gym twice a day and I was puffy fit. You guys probably can relate to that to you. like puffy fit, right? And so I knew how to do something. I was like, okay, well, this isn't working. Sarah, my wife kind of jolted me into action.

Like, hey, you don't look good either. I was like, well, I don't know. I'm hitting the gym twice a day. It's great. And I realized all my other friends who were doctors also had no idea how to take care of themselves, right? So to put it back into context with doctor school, like, you know, if your arm fell off, I was your guy. You know, if you got impaled by a fence, I'm your guy.

Right. If you have an anaphylactic reaction, I can help you. Fatigue. My penis doesn't work. You know, hey, have some skin inflammation and brain fog. No idea. So that kind of took me on the course of like, okay, well, we need to figure this out. Right. I've got to do something different because I spent all of my life trying to become this thing. And we need great doctors. And I can save a life for sure. But can I save a life on the other end. I really appreciate when doctors move into the space because you guys have some of the best training I've ever seen on how to go through and decipher through studies, data, you're trained that way. You're trained to look at things in that way. And so when you get pointed in the right direction, some of the best, in my experience, working with doctors doing what you do, some of the best results happened because you've got that training.

what was the first place you looked or what were the first things you did for yourself to kind of move things in a different direction? Yeah, for me it was, you know, just personal, it was sleep, right? So sleep is a superpower. I thought that five hours of sleep was just what we did. Yep. Right? And honestly, after I decided like, hey, this is something I need to work in or at least give myself a sleep window. Like, it's all of a sudden like my brain woke up.

but the other thing that I started looking into is like, okay, well, what am I eating? You know, who are the people in my life? All of the things that seem really, really basic. You know, if I said them on the podcast, you're like, yeah, of course. Like, that's how you fix yourself. But you have to understand and apply into your life and then do it over a long period of time. Right. So at the time when I was, this period of discovery, I was literally just looking at stuff.

And then I would dive at right in. And that's how I got connected to Nutrisense, right? If you really want me to tell that story, I was, at the time, Nutrisense was new. And now that I'm even telling the story, it was really new because I was like, hey, you know, what are these CGMs? And in fact, full disclosure, I was like, metabolic dysfunction was not taught to me in medical school, that term. And I don't even know. I mean, I've been through a lot of stuff, even more. So I'm not sure if someone even said it.

But at the time that I was trying to get healthy, it had just started to be. become popular, at least in my world. And so I was like, okay, well, you know, what is this CGM? You know, what is this company Nutrisense? So I called the company. Oh, so you called them. I called them. Oh, wow.

And that's how I did everything else. I mean, that's how I learned about peptides and that's how I learned about, I would just find something and call the person. Okay. And at the time, it was new. So usually, uh, I would get the person on the phone. So when I called Nutrisense, I was like, hey, I'm interested. I'm a doctor.

And this guy, Dan jumped on. he talks faster than I do. And so he's like, yeah, I don't do that. I own the company. I was like, well, where do I get more information? He's like, I own the company. Ask me. He's like, did you not hear what I said?

So anyways, that's how, and again, that's how I learned. I would just find something that I was interested in, figure out if it was going to have an impact in health, and then just dove right in. Well, tell me more about that process with Dan and like asking him. So you get him, you start asking questions. Are you instantly like, oh, I believe in this? or it's like what peaks your interest in it?

Do you order one and start testing it yourself? Like tell me about the evolution of that and how that unfolds for you. Yeah, well, even that first conversation was like an hour of conversation of us just talking about, you know, whatever, business, life, and how the CGM impacts people's lives. And, you know, I'm going to be honest,

when it first came out, there was a lot of heat. Like, oh, yeah, it's just a gimmick and blah, blah, blah. Yep. And so, of course, I was also trying, to start my clinic and mind you this was I don't know it was it was late 2019 and like right before COVID hit so there's a lot of other stuff going on but I started uh I was like okay let me order a few of these I had a few clients right and I was like oh this is it I'm going to put everybody on the CGM we're going to start learning about metabolic health and by the way I'm also going to learn about

metabolic health right so I started trying it um and the app was new but the big biggest difference even for me and I'll have no problem saying this as a doctor as I was learning as I went but also talking with the dietitians right and so and at the time my wife was my wife's a dietitian so she was in her residency finishing dietetics so just even getting on the even getting on the call or a zoom with these dietitians and I was I was special like hey hey I want to talk to your dietitians I was constantly wanting to talk to these people like teach me teach me what do you do here what do you here. What do you do there? So for me, it was an awesome period of discovery. And I could tell that this was a different tool because it was helping me understand how to change my behavior.

Yeah. Right? So I love like some, there's been some cool CGM stories like or CG. When you, do you remember the first like, aha or like, well, that's weird because I've seen times where you see somebody who one person eats a food and they react a certain way. And then another person eats that food reacts completely different. Do you remember the first time you had kind of like that for yourself or for a client? Yeah, absolutely. And again, like I said, we're just going to get raw on this podcast. Around the time, it was carnivore was really, really popular.

Right? So, of course, I'm trying to learn. I'm like, oh, carnivore, this has to be it. Like, let's try this. And it was the same time that I was doing the CGM. So you're eating just meat and you put on a glucose monotone? Yeah. And you're expecting zero spikes. Yeah, but I mean, even me, like, it's, you know, my wife knows how extreme my animal's like,

I'm going to be flat, dude. I'm just trying, we want no glucose spikes, right? Let's be as flat as possible. Can we pause for a second? Your wife's in residency as a dietitian and she knows you're just going to eat me. Was there like, what were the conversations like, dude? What was that like at home? I am dying because when she hears this, she's going to be like, he knows. because I would be like, no, no, nope, that's it. I would hear something be like, that's it. Plants are going to kill you.

She's like, you're dumb. I'm not doing any plants. She's like, dumb. And of course, it's fine for me telling that because you have to, you have to do this stuff to figure it out. Right? So, yes, I went through a carnivore phase and I was like, yeah, that was dumb. But no, yeah, she, I mean. But the expectation is I'm eating no glucose.

I'm having no carbs, no sugars. Yeah, yeah. No fiber. Right. And so I should have flat. Yeah. Would you actually see you, though? Yeah, well, what you see is in the longer, again, you know, I don't recommend carnivore.

The longer you take it out, the more variability potentially you have. It's wild, right. It's wild. Right. So even eating protein, you're going to have an insulin response. That's right. And so, of course, think about me. You know, I'm trying to teach people and learn.

And I'm like, okay, this is not making sense. maybe I should eat some plants and she's like, yeah, you're dumb. Yeah. So explain some, because my favorite aspect of the, of CGMs and now that they're more popular, is just something that we noticed as trainers. Now, we couldn't, I couldn't put,

I couldn't give you, you know, a blood marker or measurement, but I just trained enough people to know, like everybody responds different. It's really weird. She could eat this for the morning and then this guy eats the same thing. and it's appropriate calories. Macros are, you know, appropriate.

But he just feels like crap when it's the same thing that she does. And you just see this enough times as a trainer to go, there's a big individual variance. I can't explain it. I didn't even know how to explain it back then. But then you get CGMs that confirm, oh, yeah, like this guy eats a potato. She eats a potato. He has a crazy response.

She seems to be, okay. Explain why do we think that happens? Like, what's going on there? Yeah. I mean, when you look at variability and, you know, when I'm working with clients, the number one thing people do is they say, okay, well, I had a potato and then I have this response. Or let's say they have a response. Or like, oh, yeah, it was definitely the potato. And I was like, well, let's think about it. Let's look at all these data points because you're a human. You have a complex question, complex answer. Right. So instead of just saying like, hey, you had the potato, let's look at what happened the last five days. Was your sleep bad? did you get in a couple of arguments with your significant other? How was your hydration?

Did you work out that day? Right. So even looking at lifestyle and also looking at the physiology of the human, right? How much fat are you carrying, right? What else are you eating with the potato around the time of the potato? So it helps us kind of decipher what else would be wrong. It's as individualized as it can get. And even more importantly than I think the,

bigger conversation here is, and I remember unlocking this with clients was, because one might say, well, who cares? Who cares? Who cares if it's got this risk? Who cares? It gets a little bit. If it's the same amount of calories and I stay within my calories. But what I started to connect the dots to is when you see that, how difficult it is for the client to fight off cravings and other things when you see these huge swings. And that to me is the important conversation, is that, you know, because that's where someone, well, if I just follow calories, who cares if these foods make me go up or down? But when you talk about behavior modification and how important that is in this whole process, if you didn't realize it that you have this reaction to a certain food, it makes it that much more difficult for you to stay on track.

So talk a little bit about that because I think that's the bigger conversation more so than the variability of a client spiking or not spike. Yeah. Yeah, absolutely. I think honestly that that's the take-home message. is when you are a good practitioner or trainer or doctor or whatever, if you want to make an impact in someone's life, it's going to be behavioral modification. And there's randomized control trials that show that, right? So it's easy for me. This is an amazing tool because when someone looks at a glucose spike and they say,

who cares, for me, I can put it in context. I can say, okay, well, you know, you're a busy executive. And we know that glucose variability is going to have an impact on a cognitive function or executive function, right? When a client comes to me and they're like, hey, when I say, okay, what are your goals? They go, I want to feel better. And I'm like, okay, well, when you unpack that,

you define it. Yeah, it's mental resiliency. So cool, like you want to feel better in your body or no, you want to be James Bond, right? I want to make a decision and then have a plan to kill everybody in the room, right? So that's executive function. If I said, hey, who cares? But also when you're having all these spikes all day,

it's going to lower, it's going to lower your executive function, your ability to make decisions, right? The highest form of thinking is thinking about what you're thinking. Yeah. And so it puts it in a different context for that client. And hopefully, and again, you have to work on that over time. So not just like having one instance with the client. Let's work on it over 300 days or 600 days, right? How hard or easy was this transition for you?

because coming from someone who's a doctor, so you're one of these, you're probably the kind of guy that's like, I'm going to make a change, I'm just going to do it. I'm just going to decide. I'm just going to do it. Then you also work in the medical system,

which is like, you know, you show up, someone has something wrong, do this, do that, and you're gone. Now you're working with people on behavior change. Do you ever have frustrated? Because it's really hard to change behaviors. Yeah. Yeah.

I mean, what I would say is it wasn't as hard for me. me because that's what I like to do, right? That, I mean, I was in the military. So if you tell me like, hey, you suck, do more. I'm like, okay, sir, yes, sir. Like, cool. That's how I respond, right? I want someone to tell me. And again, you know, your circle is the collection of, you are the collection of the five people you hang out with, right? So, and in fact, that's where I shine. And everybody at the end of the day, the best doctors, they become a coach, the good ones become a life coach. Yeah. On top of taking the data, on top of prescribes. the medicine, right? You sit down with the patient and you over and over again. But it was

awesome perspective because I would go over here and try to make someone well, right, and train them on doing X, Y, Z, and then go over here to conventional medicine where people are dying. And yes, save some lives. But having that dichotomy helped me understand. Like, if you don't change, you're going to get to this side of the. Yeah. I had, I had some really interesting experiences early on as a trainer that really just defied my knowledge of blood sugar and all that stuff,

just because, you know, I understood very basic things. But I remember once I had a client was pre-diabetics. We had to test his blood sugar often. And I never forget, we had a really hard leg workout. And his diet at this point was good

because he was trying to get out of pre-diabetic stage. And he went home and he calls me up and he says, do my blood sugars through the roof. I'm like, we just worked out. That doesn't make any sense. It was the first time I understood.

understood how stress could cause a dramatic ride, just cause your liver to dump a bunch of, you know, glucose in your system. I remember when I first got that call, that they can't be right. Test yourself again. He's like, no, dude, it's real high. And I'm like, uh-oh, like, what do we do wrong? And I just had no idea that stress could cause that. Yeah, yeah, that's actually one of my platforms, you know, it's like 2026, right? You can't just be a husband. You can't be a father and have a 9 to 5. You got to now have a 5 to 9, like a 10 to 2. You got to know how to day trade crypto. So, like, all day, we are literally in fight or flight. Okay?

So, and everyone understands, like, that there's a reason. There is a physiological reason for that, right? Blue light hits your eyes, cortisol rises. You wake up and you hunt or gather, right? Again, that's a simplistic term. It gets towards the night, lowers, you go to bed. Staying in that all day is a problem. And teaching clients that, like, hey, I can make your labs like,

beautiful. We can make your body composition look beautiful. And also, I would argue that that's going to help you be more resilient. But if you, if you stay in this high nervous system activity state, it is going to kill you. And we even see that in glucose, right? One of the interesting studies that I like to talk about with the clients is like, you might not see, even with stress, you might not see that cortisol effect with fasting glucose. And when you go to a conventional doctor's office, they're going to check a fasting glucose. Right. Right. But we do see it in post-pranial. So we see it after you eat. And I always reference this one study where they artificially created like a stress test. It was like a social stress test because this is a straight nightmare fuel. And I'm saying this as I'm sitting in front of three people. But they would have you eat. So you eat your oatmeal. And then within the hour, you immediately go to another room and you have a mock panel job interview. And so then they would measure like the glucose, right? Or the other option is, you would eat and then you would go into a live audience and do math equations, right?

If you messed up, you had to start over. Right. So, I mean, and think about that, right? You might have, again, you've got to close deals, right? It's business, but you're having your meal in a high-stress situation, not to mention all the other stuff that we have to deal with in today's world. And I always tell clients, I'm like, you get what you practice. And I'm not immune to this stuff, right? My wife, the best thing she ever said to me was you love putting yourself in a constant state of shitting your pants.

And I was like, thank you. It's like, despite your best efforts, that's something really cool. You know, I'm not immune to this stuff. Like we, I deal with stress all the time. I'm a business owner. It is like this all day. And then we're expected to come home and lower our nervous system. But that's slowly killing you, right?

And so the CGM is a good way to show people like, hey, if you do this, this is not good. So we need to do something to help. Along those lines, what are some of the practices you've applied with clients to help them with that part of it? Yeah.

Yeah. Yeah. Well, and what's interesting too is when I ask them like, hey, what do you do for stress? They'll say something like, okay, well, I listen to music. And I'll push them a little hard.

I'm like, no, no, no. Which, it's fine. If music helps you. But what do you do to lower your nervous system activity? Lower your heart rate, lower the sympathetic activity, you know and one of the biggest takeaways I have for stress I learned while I was in the military you know I was deployed for a year in Afghanistan with special forces and you have that constant

high level of stress of I don't know whatever getting getting blown up and I learned it from special forces so you know where's this coming from our limbic system right limbic system wants us to be safe routine. A routine, your brain notices routine as safe. predictable. Yeah. So even in, even in war, what do we do? We clean our weapon. We go get a haircut. We make our beds, right? We prepare whatever. You're the bullets, right? So sticking to a routine will make your brain feel safe. And that's why some people think like, oh, well, that's a very boring lifestyle, but actually the brain does like routine. Was that strategically put in? by the military for that reason?

Oh yeah. Did you know that while you were going through it? Like were you aware of that or was just you reflecting and no? No, no. I was like I told you, I was just a fitness bro. Like, okay, cool, this is what we do, you know. But also, and I don't mean this to sound arrogant. My mind was not constantly on, you know,

whether a rocket was going to come over and hit us, especially when one of them hit your friend, you know. I was just, it was a very peaceful time, surprisingly, because we had one place to eat, one place to get a haircut. There was also just one haircut. but you didn't have to tell them what Eric was able to do. One place to work out, you know, and one job to do.

Yeah. So that routine, you know, I would go as far as to say there's times where I'm experiencing more stress in this chaotic environment than I did on deployment. Interesting. What are some of the practices that you've noticed that have the biggest impact on somebody's measurements, variability? Yeah. Is it exercise?

If so, what type of exercise? Is it the diet? Probably sleep routine. Sleep. Like, what are the ones that you notice most? Yeah, I mean, the obvious ones are sleep. You know, sleep is a superpower. We've, I think you guys have talked about the studies on those.

But even if you look at studies on sleep, independent of obesity, having a regular sleep schedule is going to make your glucose more stable, right? Going to bed at the same time, that's another one I had to learn, right? because I don't know what you guys and my wife's probably going to kill me but she goes to bed late I go to bed I'm grandpa Langley right I go to I try to go to bed between nine and 10 she's more after midnight and so of course I want to spend time with her when I when that even if I get an eight hour window and I try to go to bed at midnight or one I feel like shit the next day yeah right you jetline yourself yeah I mean obviously body composition so what I what I tell my clients I understand when they leave the clinic, you know, our overlords have set up the system that's going to attack you, right? Toxic people, toxic water, toxic air, toxic foods, et cetera.

So we work on making the body more resilient. And that's lean mass to fat mass. So obviously the lever there is resistance training. Yes, you should do some cardio, but trying to get that fat level down, right? Change of body composition. I love, you know, years ago, I did research on insulin sensitivity and how exercise exercise, different modes of exercise affect insulin sensitivity. And now this is what I thought I would see, but to see the studies back it up and just how much,

it was pretty cool to see that strength training of all the forms of extra, you know, it doesn't burn a ton of, a traditional strength training doesn't burn a ton of calories. You'll burn way more calories doing Zumba or running than you will, lifting weights for the same time. But the insulin sensitivity was like, in gaining lean body mass was huge. I remember reading one study with obese individuals who lost no weight. They just gained a little bit of muscle. Yep. And they saw these huge improvements in insulin sensitivity.

What's happening there? Why is it such a big gain changer? Why is it not just burn calories? What is it about building muscle that does this? Yeah. So if you look at those studies for every, I think it was for every 4% in lean mass. It was a 4% decrease in hemoglobin A1C, which is obviously a conventional test they used to check blood sugar. than 6% decrease in fasting glucose.

But the idea is that muscle is your biggest sink for glucose, right? So 80% of the glucose that's circulating is going to go into muscle and be stored as glycogen or be utilized, right? So that's step one. And then also muscle is a neuroindocrine organ. So it's going to also secrete myokines that would assist with not only brain power, allowing you to make better decisions, but also just make you feel better in general. Yeah. There was one study I read out of, I want to say it was Australia where they were looking at the impact of exercise on Alzheimer's. And they were looking at the beta amyloid plaque.

Yep. And that strength training was the only intervention they found to halt the progression and might have even looked like it was starting to reverse. And they compared to other forms of exercise. And my theory is it had to do with the insulin sensitivity because, you know, cognitive decline, Alzheimer's, dementia. Some researchers will call it type three diabetes. Absolutely. So yeah, so talk about the brain health benefits of having improved, you know, improved sensitivity to insulin. Yeah, a thousand percent. We just talked about more time above range or let's say glucose variability, less executive functioning. But when you take that out over time, obviously Alzheimer's and or dementia has a metabolic component.

And the other thing, other association I'll make is when you have metabolic disease, you have vascular disease. So one of the issues with the brain is highly sensitive to changes in energy, right? Glucose requires a lot of energy, right? I think they're clocking the optic nerve as one of the levels that requires the most oxygen. So requires a lot of oxygen and energy glucose, very sensitive. if you look at people who have insulin resistance, you're going to increase your risk of dementia by almost 70%.

And then vascular dementia is higher than that, right? And for me, you know, this is my personal sentiment, but if you look at all these problems that humans have, one component is always going to be blood flow, right? That's how the body talks. That's how it brings in oxygen. That's how it brings in nutrients. And that's how it takes out toxins.

you know so dementia's on the rise Alzheimer's on the rise and that pathophysiology is very very very similar the whole point of this talk is like how can I take a look at someone who's sick and try to not do stuff to get to that point right so someone who has dementia I mean that there's nothing worse than losing your mind especially if you're able-bodied so those are very very very those correlate strongly I always found it interesting when people would uh debate or question whether or not cognitive decline was a result of metabolic dysfunction. When we've had studies, we've been around for a long time, we've known this for a long time that if you put a person with Alzheimer's or dementia on a ketogenic diet, we see improvements in cognitive function. Not that that's a cure, but obviously something's going on there because we're switching energy sources and suddenly their scores move in the opposite direction of where they've been moving for the last 10 years. So to me, that's a thing. seems like a very obvious, like, there's something metabolically going on here.

Yeah, and you see how also how sensitive the brain is to neuroinflammation, right? Yeah. So when you have impaired glucose, you have impaired fat deposition, and that sugar that's circulating around the brain is going to cause inflammatory products. And you can even have acute cognitive changes, you know, the sugar's high. Well, I'm curious to ask you about with the rise of GOP-1s and like what you found, you know, know, in your own practice, or if you prescribe or, you know, if you've combined that with these glucose monitors and, like, what kind of data and results you've seen from that. Yeah, you know, when something gains popularity, we all win because we, everyone starts using,

especially if they can make money off of it, right? Then we all get all these studies and we see how safe it is and all the other stuff it can do. We use GLP ones, and I was using GLP ones for a long time before it kind of got popular. And so I love them. I think they have profoundly positive effects, and I'll tell you the context of how you need to use them. But it does two things. And I talked about those behavioral studies

where people were watching what they ate and they had a structured program. So the way I look at GLP-1s is it is chemical boot camp, right? So when you put this in your body, it's going to be really hard. Not until the client's like, it is really hard to eat poorly because you get really sick, right?

That's what I've seen in my clinic, right? And what do I mean? Well, if you have two glasses of wine and a piece of pizza and some ice cream, you're going to have a bad night. And so it becomes chemical boot camp, right? So even if I can't be with them there the whole time, and I'll even tell them, I'm like, hey, you're going to get sick. Not that I want you to get sick, but you won't do it again, right? And so that medication has really, really two large benefits. One, it's going to lower appetite and lower gastric emptying.

so people are going to eat less caloric restriction, and then boom, it's going to fix insulin sensitivity, or let's say, enhance insulin sensitivity. And so you even see, like, the FDA has now approved it for cardiovascular risk, right? Less hospital admissions, lower cardiovascular events, and then even kidney protection. So chronic kidney disease, they're using it's FDA approved, and kidney disease is a vascular disease.

disease. Right. Those go hand in hand. Is this, are we seeing improvements in insulin sensitivity from GLP1's independent of the, exclusively, yeah. Of the weight loss?

Like, are you, like, if someone has a CGM using GL1 before they lose weight. How do you tease that out? How do you tease that out? You'd see it right away, I guess. You would use it and you'd see. Well, essentially, you also, yeah, you can see that right away in the CGM, but they have studied the medication. They know the mechanism of action, right?

So even before, we're, again, remember, they're using this in diabetics before it got popular for weight. Yeah, yeah, 20 plus years. Right? So we already know that the, it makes the periphery more sensitive to insulin or improves, you know, glucose control within the body. So side question, maybe you don't know the answer to this, but I'm now seeing a lot of talk around PD5 inhibitors like Cialis, not for what you typically would be prescribed for,

which is erecteditis function, but for longevity. They're showing now that it's a thousand percent. There's reductions in stroke and heart disease. Do you see any different? When people use a CGM, do you see an improvement in insulin response or blood sugar response from it? Sal, are you asking me for a script? No. Just a subtle way of asking you.

Yeah. And honestly, that's how we use it too. And you know a lot of guys in gym use it for. Yeah, pops. Performance. They've been doing that since we were all kids. Whether that helps for performance or not, that's what they're using it for. So, and I can easily relate this to.

stuff that kills you. So the in product of phosphoid diasterase inhibitor is nitric oxide. Right. Nitric oxide, your body makes nitric oxide and you need nitric oxide for auto regulation, which is just a fancy term for the blood vessels relaxing and squeezing in relation to the amount of oxygen you need, right? So yeah, absolutely. Like, they're using it on the regular to improve blood flow. And as I told you, like for me, the whole discovery of me becoming this wellness This doctor is realizing, like, I'm a blood flow doctor. When organs died, it's blood flow. And that's what people die of.

It's cardiovascular heart attack and stroke, right? You don't die of diabetes. It's the same thing with sexual dysfunction, right? The same vessels in your penis or vagina are the same vessels in your heart. And they work the same way. Yeah. And so we see if somebody uses a PD5 inhibitor, do we automatically, are you seeing immediate, like, changes in their CGM reading? Is it showing up in that way or is it take longer?

Yeah, the context, yeah, the context for me is more of blood flow. Okay, so it's more of improving blood flow to organs. Sure, okay, yeah. It exercises essentially the vascular system, relaxing, contracting, keeping the endothelial. Yes, and also when you have metabolic dysfunction, the biggest issue is vascular dysfunction, right? vascular inflammation, right? That process, that cascade of, you've heard that term or, I've heard a couple of people say, like, the difference between a sick person and a healthy person is a teaspoon of sugar

in your bloodstream. The major insult is insult to the endothelium, the inner, that glyco-calyx, that slimy layer of the vessel, right? And, you know, even if you look at, let's just talk about, like, sexual dysfunction in men, across the general population it's like 25% which I think is still kind of ridiculous right that's one and four when you look at someone with metabolic resistance that jumps to like 50% it's like half so clearly that's a vascular issue clearly heart attack and stroke is a vascular issue right that's the problem so and when you have hyper or diabetes you have high blood pressure right

the diabetes is causing the high blood pressure what what percentage of your clients that you're helping a battle with sexual dysfunction? I mean, anecdotally, like, in my opinion, it's an epidemic. It's a lot. I mean, probably half of my clinic is sexual dysfunction. And this is also, this is also jaw dropping. This is, this is going to rock your world. Like, the people with metabolic, or excuse me, when you have obesity, up to a 13-fold increase

in hypogonadism. And I'm not saying sexual dysfunction is just. testosterone. Right. It's blood flow. It's multifactorial. It's all connected. Yeah.

If a guy comes to me and he's like, hey, I hate my wife and, you know, she insults me and I don't get an erection, I'm not going to say, hey, it's your metabolic health, right? Our brain is our biggest sexual organ. Right, right. So we're going to impact that a little bit. But I'm going to say, like, hey, let's look at some labs. Let's check the physiology. But I think it is an epidemic. Like, it is not only on the rise, but it's ridiculous.

And the other thing I'll talk about real quick is women. The, and this shocked me, the percentage of women across the population and have sexual dysfunction is 43%. General population. What? Yeah. How do they measure sexual dysfunction for women? Because you're not measuring erectile. Yeah, yeah.

And that's a good question because. Drive. Yeah, that's a good question because pathophysiology is the same. It's still blood flow to the sexual organs. So desire, dryness, pain, right? libido orgasm, right? And one interesting

connection I will make from that the behavioral modification, the look-ahead trial, such a prolific trial that they had these spin-off studies and one of them was

women's sexual dysfunction. And so in that trial of the people who had metabolic resistance or had obesity, 50% had sexual dysfunction with the modification. or this structured program, 30% went into remission. So again, you know, that statistic is shocking, 43%.

It's higher with people in women. But it's, you know, we see a man. We're like, okay, I can't get an erection. It's obviously a vascular issue. Right. Right. But women struggle with this too. Interesting.

How are CGMs being used now for behavioral modification? Because CGMs measure your glucose in real time. How do you combine that with coach? or, you know, behavior or two, like, what are you looking at and how are you using that as a tool to help somebody? Yeah, I'd like to you take me through a week one. I just signed up with you. I've got metabolic dysfunction. How do you monitor this? Yeah, what do you, do you just let me eat what I normally eat and monitor me first? Do you give me stuff like? Tell me what a week looks like when we get together. Yeah, well, I also, you know, again, I operate out of the clinic too. So I have the benefit of taking comprehensive labs. Right. So we, it's even even more interesting when I can.

show them the labs and then show them the CGM, which is this beat-to-beat look at their glucose. And then give them the context of like, hey, if you don't do this, these are the problems. But week one is really just, what I want to do is I want to get their baseline. Right. So do your thing. I'm like, don't, because you know what people do. Of course. You guys are in the space, right?

You know, and even when you ask that, you know, the 90% clean bros, right? I eat 90% clean, right? I'm like, okay, well, let's like test it. And that's also like the biggest takeaway is I get clowns sometimes by clients. I'm like, hey, you should, you should fit. How's your sleep? Oh, sleep hygiene. They're like, yeah, don't even go.

I know that. I do it. I'm like, okay, well, let's unpack that. Well, there's eight or nine steps to sleep hygiene. What you find out is they're maybe doing two, 40% of the time and three, 10% of the time, right? It's the same thing with all of the other lifestyle modifications. They're doing some of it, not all the time. So week one, I'm like, don't change anything.

And they still will, right? Yeah. I actually have to make it a point to like, listen, if you ever occasionally have a snickers, have that, I want you to do that thing. Yeah, you got to be, give me a week. And that's also the problem with other companies that don't have that one-on-one dietitian contact or even in my clinic. If someone puts something just the bias of checking, you're going to be living a lot better than you know.

Yeah. Right? Yeah. You're like, oh, I'm good. You know, just like perfect. Take this thing off and go back to what I'm doing. Yeah. And so that's what I told you.

The biggest impact is this stuff is, if I told you, hey, move more, eat less. You're like, cool podcast, bro. But you need to do that over a long period of time. All of these little nuances to add up. Yeah. How have you gotten to the place where the more you look at the stuff? Because I'm sure you get some of this pushback. Like, I get a plan my sleep.

I got to do all these steps. I got to look at this. that, the other. Have you got to the place where you're like, well, I think the world is just designed to make us really unhealthy. So that's why we have to do all this stuff. Because we weren't really supposed to. Wait, though.

I want to, because I know it doesn't end where, take me step by, because it links to where you're going right now. Like, okay, so the client, here's my week. And I'm assuming he's got similar advice, like how we take someone. It's not like, do all these things. Yeah. Right? Because I'm sure you've already learned that that doesn't work very well either when you

give them all the answers. So I do this week and you see all this shit that jumps out at you. And so what does it look like? Do you choose one big rock? Do you like, this is the first lever we're going to pull? Like how do you coach me through that after you get my shit labs and shit week that I give you? Because that's probably what it is for most people, right? Let's be honest.

Yeah, well, the first thing I do is set expectations and I'll even say this. I'm giving away all my little secrets, but I'll be like, look, you will know what I'm saying. Don't believe me. Well, you'll believe it when you see it, but you'll know what I'm saying is true when you feel better. But I was like, this is not going to change in 30 or 60 days. It may change in 300 or 400 days and we are going to work through it step by step, right? And I will give, you know, our slogan that thrives called empowering your health. So I'll tell the client, like, here's what I think the biggest levers are.

And I'll give them a choice. I'm like, you should start with one of these three, but only start with one at a time, right? Because I want you to see on the CGM how, what is. impact that has or the way you feel or you know your behaviors you know and and that's also what the apple do is it gives you context when did you eat how are you feeling what did you do who did you talk to right because i told you people will automatically associate something i felt like shit today it's probably because i had the taco i was like well it's probably the taco and also the stress with your you know friend i don't know yeah right yeah yeah you got to bring all that stuff

into context. And what I also call it is your health circle. And again, I am not immune to this, as you say, like the overlords have us all under this distraction and things that are killing us. So I'm not immune to that. But when I'm feeling bad, I go and data check myself and go, oh, you know, I didn't take, I didn't, I was not on my sleep game, you know, or I changed my diet a little bit or something was off. And so then the client learns put these pieces of the puzzle back in the place. They start feeling better. How do you discern between what you know is the three biggest levers and then also

what you've probably pieced together as the easiest for adherence? So this is something that over decades of coaching people, I sure have the math equation to get this person in the best shape of their life. But I also know, and I know that this is the biggest lever, but I also know too that could be a big step for a lot of people. And so sometimes I don't always advise the biggest lever or the best thing. So how do you like first of all, give me what those kind of levers are and then how do you discern where you go first with a client? Is it always the same or is you notice based off of the conversation like this guy's going to have struggle doing that pulling this lever?

Yeah. Well, for me, the biggest levers personally that I work with the clients are got to be, they have to be really. resistance training followed by food, right? You know, and specifically, let's just say that, you know, for me, I told you it's, we want to make the body resilient. Yeah. Right? I want to get their body composition better to make them this well-oiled machine and go out in the world and handle toxins, whatever that is. So we know that that's resistance training and also probably is going to be a caloric deficit, which means we got to stick with protein. I understand that that's going to overwhelm them, but I try to stick. to something that's going to build trust.

And generally, when people start losing weight and they feel maybe they have a little bit a better body image so that it puts them in a positive state of mind. You know, one of the ways the brain works is error correction. So everyone thinks like, okay, cool, you know, dopamine is a reward molecule. And it is, and it's all about anticipation, but it's error correction. So if you look at high performers, they are in this range where it's not too hard and not too little, right? You don't want to make it too hard or too little.

Just write where you make a mistake, fix it, and the CGM can show you. Yeah. Like, hey, you did great all week. And then Friday, you just, I don't know, you shit the bed. And then boom, you feel bad. Correct and get bad. That's, you get dopamine in your brain. So that's how you actually rewrite your brain.

It's so cool to hear you answer the, in that way, coming from your profession and your angle, because I feel like, although we're in similar fields, we come at a different angles. And those are the first two things that we tell people. And it's, it's, can I get them to the gym once or twice a week, full body, straight training routine? And can I get them to eat high protein? Yeah.

And it's, and those two things are such big rocks and levers that it does tend to fix a lot of the other things. And if I can just get them to commit to that, then I could start to, to build off of that. So to hear you say that from, you know, where you're standing and all the, like, that just shows how many people you've probably helped. in your career because that's what we talk about all the time. And people kind of mock or, you know, make fun of or scoff at that. That's like what we simplify down to it.

It's like, man, those are such big rocks that if someone consistently hits high protein intake, we know that it's going to naturally start to modify their cravings and their calories. And if they just do two full body workouts a week, the amount of muscle and strength that they can build and what that will do metabolically for them, strength wise for them, And a lot of times it even improves some sleep and energy. So it's cool to hear that. That's what you distilled it down to. Yeah,

and we've got the studies to prove that, right? You know, I'll just to follow up on that, it's cool that you said that too, because I think that having diagnostics in advanced medicine is great. It's awesome. You know, I studied in Texas Medical Center, MD Henderson,

there's all this stuff. But I think what happens is we scoff at, so we have a bunch of advanced diagnostics and the treatment may still be very coarse, right? It's just tell the guy in the bottom of the boat, like, hey, we need more coal. You know, or hey, less coal, less coal. And people look at that and they're like, that's basic, dude. Like, really, that's what's going to change.

And it goes back to what I'm saying that if you did that, and yes, I'm not saying only that. There are nuances for a long period of time, you would win over time, metabolically, chronic illness, etc. What I find interesting about CGMs is that watching someone's glucose in real time, you can actually diagnose, or at least it points you in a lot of different directions, not just food. For example, how many times have you seen someone's CGM spike in the middle of the night and say, oh, you might have sleep apnea? Yeah. Let's look at your sleep and see if you're snoring or what the deal is. It's interesting. It points to a lot of different things because a lot of things can cause a spike.

Yep, and that's the benefit of continuous data. Because before that... How would you know? Yeah, you wouldn't know of anything that's going on. And go ahead. How do you use this data then to coach someone? Is it questions? Like, hey, we're noticing this and that.

What's going on? What happened at that time? Yeah, I mean, again, the platform that I like to use is let the client figure it out themselves with my guidance, right? So it always starts with asking like, hey, you know, one, just the thought of them putting the CGM on, they start taking more data points. And you check your own health journey. Like without the CGM, you're maybe not thinking about like, oh, man, I feel bad.

It must be, you know, again, this, you know, whatever I ate in the morning. It's probably a collection of stuff. So with continuous data, we can go back and look at it. The other thing that Nutrisense is doing right now is leveraging AI. So they have this Nora, right? that will put this stuff in front of your face. So again, we know the best way to went with a client is touch points, right? You honestly just flood them with interaction.

And so Nora will bring up trends and bring up data, even data that looks the same across weeks or like when you're putting in inputs, it'll show you outputs, right? So it bridges the gap between your meetings with either the physician or the dietitian. Any supplements that actually make a difference with what you see on the CGM? Like berberine? I hear about berberin all the time. Yeah, berberine is great. There's berbering, there's alpha lipoic acid. And you'll actually see it?

You'll be able to measure it. Yeah, the difference, though, is that just remember that all in context. So berberine is not instantaneous. And that's because also bioavailability. So you need to take it over a long period of time. Another one is like myoanacetal. That one's awesome. So it's also used in like PCOS.

So like, you know, that's a great one. But we're just working on basic deficiencies, iron, vitamin D, magnesium, zinc. But yes, I mean, you know, again, it's complex answer. Answers complex questions, right? You got to take berbering for a long time. It's hard to just say, hey, I took berbering and then I saw the effects. Got it. What about the GMO product that Zbiotic makes?

Oh, you know, there are. You'd be a great person to ask that. Yeah. Yeah, so they made a product that this bacteria is modified to convert unused sugar into fiber. Acrimancia? Good question. I'm not sure. But I know that they modified the bacteria.

So it's their own patented, whatever. That theoretically should make a difference, right? Because it goes from... A thousand percent. Okay. Okay. Yeah. That would be a fun test then.

Yeah. Be cool to give you something. Yeah. Yeah. And again, extend the study over time. Right. Like, you've got to make it almost like a cut out all the other variable. Same meals, same timing.

Of course. But the gut also, they're nutritions, they do a gut microbiome test. So we're understanding that gut is very complex. It's a great way that food interacts with the world. And when the bacteria are in proper alignment, they can help your glucose. It's interesting you brought up myoanostol because that's been promoted forever as an anti-anxiety supplement. And I'm wondering now if the anti-anxiety effect is from a regular, of blood sugar.

Yeah, well, and one of the things it does is it helps cellular movement. So, like, storage to the end of the cell, to the nucleus. So DNA basically enhances mitochondria. It's just like in any. Anything you enhance mitochondria, you can have lower inflammation, lower anxiety, better sleep, et cetera. Creightine, you recommend. So along those lines, you must recommend cretein quite a bit. Million billion thousand percent.

It should be part of your daily stack. You even have done studies that show, so data that shows when paired with exercise can improve glucose sensitivity. And then, of course, we know now that we're stacking it for brain effect too, right? You just have to do more. I think brain absorption is a little less. Yeah. So pump your dose. Yeah.

You brought up the alarming stat with women, the 43%. Anything else, and you're such a data-driven guy, you got all this great analytics that you can go back to. Anything else that was alarming to you, that you've come across that, like, surprised you or was like, man? In the data? Yeah, yeah, just. Yeah, there's another, like, another one that comes to mind, and it just deals with men. It's prostate. So as we're aging, a lot of people are having prostate issues, right?

And I mean, again, even me going up through the medical community, it's like just something that old guys had, right? They just went to pee five times a night. And so you see that, so now we're also starting to learn that's also a metabolic component. So the data is now showing that with insulin resistance and there may be a dose response, so the worst it is, the larger the prostate. So it can increase your risk of BPH, hypertrophy, threefold. So again, if you talk about the impact on a man's life, sleep, if I'm having to get a five or six times to sleep, is going to destroy everything else.

Downstream effects. Yeah. So we fix that in the clinic and it's life changing. It's something that people overlook. I mean, a guy will come in and be like, I'm only going to pee once a night. Changes his life. Wow.

Not to mention improved blood flow and sexual functions. What about, so you hear now a lot in regards to cancer that one of the driving forces behind cancer is metabolic dysfunction. Are you up to date with some of this research? Cancer is very complex, but... Yeah, yeah, yeah, no, and that brings up a good point.

So when you talk about metabolic dysfunction, everyone understands glucose, but the other flip of that coin is fat deposition, right? So when you're, when this system is impaired, you have a tendency to add fat and not just fat, it's bad fat, ectopic fat, visceral fat, that's the fat that kills us. And so if you look at the risk of someone having high visceral fat and increases, cancer risk by 44% and I'm talking about colon cancer, pancreas cancer, like the stuff that can kill you, right? And then the other really important statistic of just having visceral fat is increases your

mortality twofold, right? So we know there's a connection between metabolic resistance and cancer. And yes, glucose has an effect, but I just want to point out that abnormal fat deposition, which is killing people, right? big, big, makes you big risk factor. When you look at just studies and surveys on people that lose weight and the fail rate is so high, right? Something like 85% or 90% gaining the weight back type of deal.

Do you see greater success rates when people lose weight through using a CGM and a coach versus doing it on their own? What does that look like in comparison? Yeah. I wish I had some cool statistics on that. I can just tell you in reality. you guys are in the same space, right? And, you know, what I can point out is those RCTs are just really, really large trials, as I told you, of behavioral modification.

What they were given was coaching. So they had behavioral groups. They were taught what macros are or they were taught. And then they had follow up. And even the effects of positive, you know, lower depression, lowered anxiety and how they thought they had. they had a lower perceived stress of sticking to a plan. So that take-home message is like, cool, you can get a CGM, cool. You know, you have these companies where you can just go like, hey, I can order my labs.

It needs context. Yeah. It needs follow up. And even like, you know, as a physician, like I can't do it all, you know. So a whole team. And that's how we work in my clinic as well. Yeah. Yeah.

No, I would have guessed that for sure. Just from my experience, I think behavior change is hard. And it takes some time and you need a coach there and then you need some grace and you're going to screw up and then. Yeah. But over time, far better success rate. Tell me a little bit more about the AI that Nutrisense is using. I haven't played with that in a while. And so like is it giving me like it starts to pick up on my patterns of like Saturdays I tend to do these.

Oh, wow. And does it give you like a notification or something? Yes. Yes. Positive and negative kind of trends. Yes. It puts it in your face. Oh, that's kind of cool.

And the other thing too. is the more inputs, more outputs, right? So if you're saying, hey, I went to bed at this time, hey, my day was stressful, hey, I worked out, it's going to tell you last week you did this and this is what we saw. And so think about that when I can't sit there and harass you and it's, it's, you know, harassing you to like think. Yeah, yeah. Well, what's so cool about that is one of the things that we talk about a lot in the show is

that a lot of what you do with good coaching is really just, helping clients connect the dots. Totally. You know, half the time, I mean, and we're all probably all in this room, guilty of this at one point in our lives, you know, eating foods that totally didn't agree with us and just thought that your stool was normal. That's just, you have a bad day.

It was like, not going like, no, that's actually because you ate this thing. Right. You felt that way. Also, your sleep was, it's like, it's just, we're so, it's amazing to me how disconnected we are to how food affects us and how the, and just, so a lot of it's connecting us. So now having an AI tool that's monitoring you that's kind of giving you that feedback loop is incredible because it's like an ongoing coach who's just kind of reminding you like, because then they start to connect it. I'm sure they go like, oh shit, that's the third time

that I didn't get to bed at this time. And I also know. So one of my favorite things to talk about with the glucose monitors that I noticed and it was that poor nights asleep, the cravings on the next day. Yeah. What like that was mind blowing to me. And literally, Just becoming aware of that may help me combat it in the daytime. So it was just like, if I knew I got up and it was like, Dan, that was a poor night I slept. I know what I was in for that day. And because I was aware of that, it made me, it made it easier for me to resist that.

It was like, why all of a sudden I'm craving this crappy food? I've been on my diet. It's like, oh, that's right. I've got that bad night of sleep. I think things like that, like people just don't realize how much of what's going on with their sleep and their habits are connected to all these cravings. and other in their moods and all the stuff. And so having an AI tool that is also giving you that feedback, that's, that's rad.

Yeah, it's huge. It's just like I talked about, you know, when, when something happens, you correlate it with something that day or maybe the day before. What if it, you know, complex questions, complex, what if it was seven days before? What if it was 15 days before? So aggregating that data really expands like, whoa, it's very thought provoking, right? Yeah. And even if you know, so, hey, I had a bad night of sleep.

I know when I have bad a night of sleep, I have cravings. Stick to your routine, right? You're like, I am not going to even go over there where the ice cream is or whatever it is, is your weakness, right? Yep. How well or how quickly is NutriSense growing? Because they're one of the best at combining kind of coaching with monitoring. Is it a growing field in general?

And how's Nutrisense doing with it? Yeah, NutriSense is crushing it. I mean, you know, I don't know of another company that utilizes coaching. And so yeah, there are other CGM companies. Yeah. But the coaching is where it's at or the one-on-one with dietitians, with experts. And so people want that, right? I mean, I have a bunch of clients that come to me that are fallout from, you know, hey, I got my labs. No one helped me, right? Putting it in context. So Nutrisense is blowing up in that sense. And so, yeah, it's really exciting. And then the other thing, too, is when, as I said, when something gains popularity,

we get to study it. So hopefully the future forward is continuing to look at this data and then trying to get real-world stuff. For example, like they're looking at CGM and changes in arterial flow, which would lend itself to like, hey, what's going to set you up for death, cardiovascular disease, right? Right now I can't say it's a diagnostic tool, but the more data, the more we can see. The whole point of the talk is how do I not end up over there? One, how do I feel better? And two, how do I not end up sick or dead? What do you do for Nutrisense exactly?

Or with Nutrisense? Yeah, so I am, so currently I'm the medical director. And you know these CGMs are being offered commercially, but if you were to get a CGM back in the day, it would come through me. You might see my name on it. Yeah, I got a lot of phone calls in that day. Hey, Dr. Langley, I need another CGM. I was like, oh, talk to Nutrients.

But yeah, no, I mean, I work closely with, the dietitians and the team at Nutrisense, you know, my clinic handles stuff, complicated situations in a much larger, a conglomerative stuff, but we work hand in hand. My clinic is very much like talking to people at Nutrisense. We use the dietitians at Nutrisense, et cetera. How did that, how did that, I mean, you talked about how that relationship started and you almost were like a customer first. Yeah. How did that develop into the relationship you have now with them? yeah well like i said um and dan's probably going to kill me for telling the story but you know dan and i built a relationship because i was just interested i wanted to know everything

hey let me talk to your dietitians and at the time i was doing stuff across country right so i had all of these medical licenses and um once we built a relationship he was like hey uh because we were they're having trouble getting the cgms out he's like hey i need a doctor who's willing who's excited, who talks really fast like me, and has some medical licenses. And I was like, cool, I need a CEO that talks faster than me. Like, let's go. So that's really it. Like, that really started the whole relationship.

Oh, wow. And a little bit of other truth here, I was more excited. I was like, hey, teach me, let me use this stuff. And, you know, I'll be your medical director. No payment, nothing like that. That's so crazy. So that helped. But it did supercharge me into like building my own,

own clinic and learning more. Now, have you guys become friends or just business? I mean, what's it? Have you guys, I mean, imagine you're, you're bugging him that much. He brought you in. You guys probably built somewhat of a relationship even though. Yeah. Yeah, we're bros.

We're bros. He's always trying to get me to hang out. And I'm always telling him like, dude, I have a lot to do. But yes, yes, we'll go to Burning Man at some point. I'm not having a CGM on when we do that. Okay. How are peptides showing up on CGMs?

Are you noticing any changes? I'm assuming the growth hormone releasing ones, you'll probably see an impact. Are you seeing anything with like the BPCs and the... Yeah, that's a good question. Haven't specifically studied it, but, you know, again, even with peptides, like, in my opinion, very safe molecules,

the longer you take them, the longer you have to understand what they do. So some of those growth hormones, the cretagogues, If you look at some of the studies, I think it's closer like a week 11, 12. If you're on it, you may have some increase in IGF1, which we know is going to change glucose a little bit. So that's a good question. I haven't really looked at that yet, but honestly another tool in the toolbox to show people.

What about hormone therapy? How is that changing or improving? So the guy comes in, low testosterone, doesn't rise from improving behaviors. Put them on testosterone. What do you see typically? in their overall health. No, and there's CGMs. Do we notice anything with improvements?

Well, downstream for sure, because then they build muscle and then you see it. Yeah, sorry. Yeah. So, again, to me, like having normal testosterone

lowers cardiovascular risk. Why? We know it's going to burn visceral fat, and that's the major killer. Two, it's going to help you add muscle. I've seen one study where it says it may almost add up, even without working out, you may have a change in like 7 to 8%

really massive. That's wild. That's insane, right? I told you, every 4% lowers your hemoglobin A1C, like another 4%. So you do see a downstream effect, right? And then, again, having metabolic resistance is going to increase your risk of hypogonadism up to 9 to 13 fold, which is, like, ridiculous, right? So it's an epidemic, and there are certain things you would want, better sleep, better mood, and better body composition. fix your testosterone.

Now, I know you haven't, you haven't had your clinic for decades, but have you noticed, even in the short time you have, uh, the rise in like young men with like, epidemic. Yeah.

Epidemic. And in fact, I forgot to say this, but so across the general population, let's say it's 24%, but a new study came out last year where they looked at 18 to 34 year olds and they gestured and this was a questionnaire. 34%

which is insane and also I personally believe that it's underreported right because you know you're not you don't really want to tell someone at that age maybe you have problems I know it's underreported because we get DMs and messages

from young men all the time that haven't even gone and seen their doctor and talked about it and so there's not not everybody's reporting it where it gets tricky is and you know as a good clinician understands it's not an absolute number right you know you may be low and not having symptoms low or you may be normal and having symptoms right you have to look at the number bait and and talk to the client yeah i would imagine that's due to poor health and probably pornography which is real common now in young men a thousand percent yeah so it's probably a good combination of the two because i mean historically you would not see any

sexual dysfunction in that age group that's like when you don't have any yeah and that's the other thing to point out it's not all like i said it's not all metabolic health a guy comes in and says hey i'm looking at porn and I'm masturbating like 37 times a day. I'm going to be like, hey, let's unpack that a little bit. That's probably not healthy. That's not as too much. Come down. Jeez.

Right. Justin, wait, 37? There's some numbers, right? You're all getting see Alice after the show. Well, good deal. Yeah, dude. Well, this would be great, man. Thanks for coming on.

I appreciate you. Yeah, thanks for having me. Kind of breaking this down. I think the future of, I think far more people now are becoming aware of the value of coaching. I think that GLP-1s or GLPs have increased the awareness around it because, yeah, you lose weight, but you also lose muscles. So now, you know, your typical doctor saying you might need a strength train. And so I think that this is all good.

I think we're moving in a better direction than we have in a long time. And you add a, you know, a glucose monitor to that. And you've got this one. We've never had tools like this. Like as a trainer, it was just me and my client. but if I had a glucose monitor and if I had a GLP1 working with some of my clients that stroke, I think my success rate would have doubled for sure. Yeah.

Yeah, and we're going to see that. For sure. We're going to see that. This is the future. Very close. I would just say, you know, if you're going to set up a clinic, you're going to have a program, you got to have good coaching. For sure.

I don't care if you're a doctor or whatever you are. Agreed. You've got to spend time with these people. Agreed. Thanks for coming on, man. Yeah. Thanks for having me. Thank you for listening to Mind Pump.

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