Mind Pump: Raw Fitness Truth - 2837: The Methylene Blue Masterclass: Cutting-Edge Mitochondrial Support with Dr. Scott Sherr

Episode Date: April 16, 2026

This is one of the BEST interviews we've ever done on supplements and cutting-edge supplement technology... We had Dr. Scott Sherr on the podcast — a board-certified internal medicine physician who ...practices health optimization medicine and hyperbaric oxygen therapy. This guy KNOWS his stuff and we break down some of the most powerful compounds you can get your hands on to improve cognitive function, athletic performance, and longevity. Here's the reality... 94% of US adults are metabolically UNHEALTHY. That means your mitochondria — the powerhouses of your cells — are struggling to produce the energy you need. Dr. Sherr explains exactly why this happens, how it connects to everything from anxiety and depression to fat loss struggles, and what you can actually DO about it. We dive DEEP into methylene blue — the first drug ever registered with the FDA back in 1897 — and why it's become one of the most powerful tools for supporting mitochondrial function and energy production. But it doesn't stop there... We cover the GABAergic system and why most people are walking around GABA deficient (hello anxiety, insomnia, and mood issues), the synergy between methylene blue and red light therapy, how to use these compounds for travel, and a complete sleep optimization stack that could finally get you those 90+ Oura Ring scores. If you're tired of being tired, stressed about being stressed, or just want to understand how to actually support your body at a cellular level — this episode is a MUST listen. MAPS PPL — https://mapsppl.com (code: ppl) SPONSORS Troscriptions — https://troscriptions.com/mindpump (code: mindpump) Seed — https://seed.com/mindpump (code: 25mindpump) 00:00 — Intro 5:56 — Dr. Scott Sherr's background and health optimization medicine framework 10:42 — Strengths and weaknesses of conventional vs alternative medicine 16:34 — Why 94% of US adults are metabolically unhealthy 22:30 — The 'sympathetic spiral of doom' and why doing MORE isn't better 25:48 — Deep dive into methylene blue — history and mechanisms 35:09 — MAO inhibition, serotonin syndrome risk, and dosing protocols 42:43 — Methylene blue and red light therapy synergy 48:55 — GABA system, B3-GABA, and the TroCalm formula explained 59:58 — Complete sleep optimization stack and nighttime routine 67:30 — Cordycepin benefits and immune support protocols PEOPLE MENTIONED Dr. Scott Sherr — Guest — board-certified internal medicine physician, health optimization medicine practitioner, co-founder of Troscriptions Dr. Ted Achacoso — Founder of Troscriptions and the Health Optimization Medicine nonprofit, mentor to Dr. Sherr Alan Sherr — Dr. Sherr's father — chiropractor for 45+ years who influenced his alternative medicine philosophy Francisco Gonzalez Lima — Researcher at University of Texas Austin studying methylene blue for Alzheimer's, TBI, and stroke Thomas DeLauer — Mutual friend who uses methylene blue 2-3 times per week on high-stress days Paul Stamets — Referenced regarding mushroom knowledge and Amanita Muscaria/Santa Claus connection

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Starting point is 00:00:00 If you want to pump your body and expand your mind, there's only one place to go. Mind Pump. Mind Pump with your hosts. Sal DeStefano, Adam Schaefer, and Justin Andrews. You just found the most downloaded Fitness Health and Entertainment podcast. This is Mind Pump. This is one of the best interviews I've ever done on supplements in cutting edge supplement technology. It was so informative.
Starting point is 00:00:26 We had Dr. Scott Cher on the podcast. He's a board certified internal. medicine physician. He's also certified to practice health optimization medicine and hyperbaric oxygen therapy. But he knows his stuff. And we break down some of the best cutting-edge supplements that you can get your hands on to improve things like cognitive function, athletic performance, overall health, longevity. This episode is brought to you by Troscriptions. So they make some of these incredible supplements. In fact, Dr. Scott Cher, he's one of the founders of this company. So you can hear them talk about a lot of stuff, and you can get this stuff here.
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Starting point is 00:02:58 All right, real quick, if you love us like, we, We love you. Why not show up by rocking one of our shirts, hats, mugs, or training gear over at mindpumpstore.com. I'm talking right now. Hit pause. Head on over to mindpumpstor.com. That's it. Enjoy the rest of the show. God, welcome the show. Thanks for having me, guys. This has been, this is great already. We're already having a good time. So just for the listeners, tell them a little bit about your background and what you do. Sure. So I'm a board certified internal medicine physician. I practice something called health optimization, which is a it's it's based on a nonprofit actually that we help run it's called
Starting point is 00:03:34 health optimization medicine and practice it's a framework that optimizes health rather than focuses on disease it's a if you're a clinician you want to look for more training and a different perspective it's really cool and it's a seven module certification for people and so I use that as kind of the foundation of my practice I'm also specialized in something called hyperbaric oxygen therapy which I've known and used in practice for many years when I was living in the Bay area actually as well and then I helped run a couple companies, one called Transcriptions.
Starting point is 00:04:02 It's a company that helps people right now on the longer path of optimizing their health. And I'm the chief of education, outreach, I don't know, my title just changed. It was something and now it's something else. But I do a lot of education outreach, media, and a lot of teaching. I still have my own clinical practice. I do it most through my house in Colorado at this point. And I really try to kind of give people a navigation on, you know, some of the more difficult things that we're focusing on these days, energy, stress, anxiety, sleep.
Starting point is 00:04:30 immune system function and how we can really help people now while we're on the longer path of helping people long term. In my experience, when I've met physicians who have moved into a space that seems more preventative, there's typically a story behind it. I was just kidding. I was just going to ask, you didn't land there. Did you? Oh, no.
Starting point is 00:04:47 So there's two ways this typically happens, right? The first way is not my way. The first way is you're a doctor and the system fails you, right? The system fails. You or your family. And then they can't get help and they look for alternative things. and they get into the functional integrative world, and that's how it goes.
Starting point is 00:05:03 My story is a little bit different. I grew up the son of a crazy motherfucking chiropractor. So my dad. So his name's Alan Scher, and he's a practicing chiropractor for over 45 years in Long Island in New York. And so I grew up in his practice. I grew up, obviously, I was adjusted when I was born,
Starting point is 00:05:19 and then even when I was a kid in high school, I worked at his front desk, I was really good at collecting money because I knew that was the money I was getting for spending money and also for college, right? So I grew up very alternatively, and I didn't really know a lot about conventional medicine until I decided, actually with his guidance, to go to medical school. The idea being, well, I grew up pretty crazy.
Starting point is 00:05:40 I kind of had an understanding of that alternative world, at least in philosophy, then I would learn the medical stuff and then figure out what to do with my life. And so as a result of that, I kind of took the fastest path out of medical school you could, which is four years of medical school, three years of residency, which is still a lot, but that's the shortest. and then from there gravitated towards creating my own integrative practice where I see people from all over the world using that health optimization medicine framework along with using other tools and technologies and practices and supplementation and things like that. So that's the story. Do you still remember, can you remember or recall when you realized you were growing up an unconventional medicine? Oh man. I mean, it was always weird in my house. I mean, because in that time there was no functional medicine, there was no really integrative medicine. It was
Starting point is 00:06:27 just like OG alternative health chiropractors, really, that we're doing it. And so it was always something weird happening in my house or close to it, right? I was even talking to my dad. It was good. You actually like this story is that we have a very small podcast called the Health Optimization Medicine podcast and I interviewed with my father for it. And he was telling me all these stories about my childhood and about growing up and like he was in communes before he started the practice and like all this crazy crazy stuff. And I was like, oh, this makes so much more sense. So but some cool stuff. I remember being a kid and him taking off people from dairy and from, you know, from like sugar and things like that. Before it was popular. Before it was popular. In the 1980s, he'd take people off of dairy.
Starting point is 00:07:05 Their allergies would go away. Their asthma would go away. Like they could function better. And so I saw him doing all these crazy things back then. And it's kind of come full circle for me now. Because now I have my own practice where that philosophy is a big part of what I do. But now it's a little bit more data driven. So I do laboratory testing and use a field called metabolomics, which is this cool study of like small molecules of how the cells work. Yeah. So, but I'm always, he's still one of my, you know, my biggest mentor is that I talk to him all the time.
Starting point is 00:07:32 And he's always a big fan of the things that I do. Now, because you came from that and you saw things like that as early as in the 80s, were you the pain in the ass student going through Western medicine? People were like, it was so weird because people go to pizza parties all the time. I'm like, why would the fuck we eating pizza? Like, this is medical school, right? And like, it was, I was definitely a pain in the ass. Yeah.
Starting point is 00:07:53 But also, you know, part of it is when you're training, you just kind of put your head down and you train, right? So it's school, right? So there were times, oftentimes, because the thing about medical school is that, like, you spend like a hot semester on anatomy and physiology, you do your dissections and all that thing, which I was not very good at. That was not my thing. I was never going to be a surgeon. I had this reputation of being the oops guy. Like, I'd absolutely break. They were already dead, though. okay. So that was okay. But there were times, you know, there were times when I was like, what am I doing? Why am I here? Because sometimes you'd be very, very quickly after alerting anatomy and physiology, go directly to path of physiology and disease and treatment, right? There's no like, how do you keep the body healthy, you know? And that's what kind of how I grew up with that
Starting point is 00:08:40 philosophy is like, right, if you give the body what it needs, it's going to work the way it's supposed to. And, you know, my dad actually had this really interesting saying back in the early 90s. He's like, Scott, the most powerful drug you can ever take is the food that you eat. This is like 1992, right? Nobody was talking about this at the time, right? He's very, very prescient or very whatever it is, you know. And so for me, it's always, it's been like a mission to go back there. Yeah.
Starting point is 00:09:03 And then this health optimization medicine framework that I use in my clinical practice that's based on another mentor of mine, and a guy that I work with now, he's actually the founder of the nonprofit and also to descriptions. His name's Dr. Ted Ochoco. Dr. Ted is this polymath, brilliant dude. And he created this framework. And he's like, what if we can optimize health,
Starting point is 00:09:22 rather than focusing on disease and keep people healthy, not just looking at early onset of disease or like, we have standards of care for like diabetes and high blood pressure, but there's no standard of care for health, right? And that's what he was trying to develop. And so I signed on almost immediately when I met Ted in 2017 because it was like,
Starting point is 00:09:40 this is it. Like this is what I've been waiting for is like some way to bring everything together. This is interesting. It's so crazy because it's so true. Chiropractors were the original alternative medicine practitioners before that even became. thing. What were the, what are the strengths and weaknesses of traditional Western medicine? And then what are
Starting point is 00:09:57 the strengths and weaknesses of alternative? And how are you trying to bring those together? Well, I think the strengths of the, the acute care system is that we're really good at acute care. Like, I worked in Baltimore at a place called the Shock Trauma Center. And if you can imagine, have you guys watched The Wire before, you know? One of my favorite shows. Yeah, it's a great show, right? So I actually lived in a building that's like a cracked out building in the show. And that they redid afterwards is called silo point and kind of funny story there
Starting point is 00:10:26 but in Baltimore lots of shock lots of trauma lots of gunshot wounds so you gotta shock trauma and like most of time like even you come in like with ridiculous
Starting point is 00:10:36 ridiculous things that you mostly live right we're I mean I can tell just a quick crazy story like there was a lady that came in with a knife in her chest okay and I'm the third year medical student I'm on call
Starting point is 00:10:47 every three nights for 30 hours like that's called Q3 This is actually where I learned about hyperbaric therapy, interestingly enough. So on call every three nights for 30 hours, for three weeks, like one day off. So the way that works is that you're, just to kind of people give a sense, you work for 30 hours, you go home, you sleep for four hours, you wake up, you have dinner, you go back to bed, and you go back and you have two regular days. Then your third day is like that again, 30 hours, okay. So it's crazy. But in the shock trauma center, this lady came in, she had a knife in her chest.
Starting point is 00:11:20 She was completely talking to us, right? No problem. But all of a sudden lost all their vital signs, right? And so if that happens in a trauma bay, what you do is you crack their chest open right there without taking them to the OR. So they cracked their chest open, open it. And I watched her heart just spurting out blood, every beat.
Starting point is 00:11:37 And they actually were able to sew something onto her heart to stop it from doing that. And she lived. It was the craziest thing we ever seen. So we can do amazing things in acute care, but we suck at almost every. everything else when it comes to the conventional system. Primary care, prevention care is okay in some ways, but they're not looking for keeping you healthy, right? They're just keeping you
Starting point is 00:12:02 trying to find early signs of disease to keep you from dying, right? And there is a, I think everybody needs to get a colonoscopy. Like, I think if you're, you know, male, female, you're over 40, 45 years of age, like, get screening tests can be very important because they can find early science because most of us are just really unhealthy in general. And that's the other issue, right? Like 94% of U.S. adults are metabolically unhealthy, right? So it's only 6% are metabolically healthy. This is why mitochondria become a big deal, you know, which I'm sure we'll talk about later. But in essence, I think what conventional care is really good for is acute and interventional care. Now, aside from that, not very good at much else. We have to manage disease. They can manage disease,
Starting point is 00:12:44 okay, but they're not looking at trying to reverse disease, not trying to cause. try to get to the root cause of anything, right? So we're non-conventional medicine, so integrative, functional health optimization medicine, the things really come in is like, how can we look at the root causes, first of all, for sure. But even in addition to that, how can we keep people healthy?
Starting point is 00:13:01 How can we optimize them at a foundational level? And that's really where I think things are going, right? I think that's what you guys are all about too, right? Which is like, let's take things out of that system. Because once you get in the acute care system, it's really difficult to get out. And I worked in the hospital for many years. I worked as a as a hospitalist.
Starting point is 00:13:18 Have you guys heard of a hospice before? No. So a hospitalist is like your primary care doctor in the hospital. Okay. So you have a primary care doctor that will see you and that will send you to a specialist and like, you know, what a primary care doctor equivalent on the hospital, a hospitalist does,
Starting point is 00:13:32 is be your primary person. And then if you need a cardiologist, you get a cardiologist. If you need a gastroenterologist and things like that. So I do that for many years. And like it's okay. You know, it works. But it's like grinding people out, most of the time, where you find that you send somebody home,
Starting point is 00:13:50 they're going to come back four or six months later with something else, right? The system is not good at reversing anything. It's just good at managing. And then we have a pharmaceutical system that's very, very good at keeping people on medications for the rest of their life because that's how they make all their money, right? If you have a blockbuster drug, I mean, Viagra not excluded, although now we can take Viagra all the time, right? No problem.
Starting point is 00:14:10 It's good for vascular health. It's good prevent dementia and things like that. or I was just at 18,700 feet at Everest Space Camp. You can take it up there. It helps too. Yeah. Where you walk around with half of an erection at the same time. No, that's not why.
Starting point is 00:14:24 That's not why. That's not why. That's because it's good. There's good. So anyway, I think the conventional system is good at acute and preventional care, but it's mostly a grinding system. I mean, I have friends of mine in the system. Like, it's a meat grinder.
Starting point is 00:14:39 That's what you call. You grind people in. You grind people out. You only have 15 people. minutes with somebody and you're done, you know. Yeah, part of the challenge, I think, too, Scott, just to give some, because I've, over the years of being a personal trainer, I've trained so many doctors. At one point, I had a studio, I was down the street from a large hospital.
Starting point is 00:14:58 I trained one. The next thing you know, they're referring each other, and I'm training all these doctors and surgeons. And they're good people. They really want to help people. And we would talk about this all the time. I'm obviously in fitness and health. They're, you know, treating people either through surgery or through medications.
Starting point is 00:15:11 part of the challenge too is preventative care is requires more from the patient. It's not just take this pill, which by the way, the data on even people forgetting to take their medication is pretty silly. Yes. But it also just requires more. Like getting someone to take a pill versus change your diet, the adherence is a lot higher with the medication. So how do you work with that?
Starting point is 00:15:34 Do you probably get more of a self-selection bias of people who are willing to? Yeah. So maybe I don't know. Talk about that a little bit. I mean, I think what it's coming down. to is that there's a lot of democratizing of information now, right? And so that's a really a good thing, because now it's not like the doctor's telling you everything and that's it, because 20 years ago, you just had the doctor to listen to. And then there was Dr. Google, which was good, but also a pain in the
Starting point is 00:15:57 ass because if you look and you see you have like a hang nail, you think you're dying of cancer. And so you have patients coming out, I'm dying of cancer doc because of this hangnail or whatever, right? And now you have Dr. Chat, GPT, or whatever, right? And so there is definitely negatives to that because it becomes like... Information overload. Yeah, information overload, exactly. But at the same time, it's more democratized so that you can really get people more interested
Starting point is 00:16:21 in helping themselves. And you're right. So for me, it's a lot of a self-selection bias. But what I found over the years is that you have to give people some glimmer that there's a different way to do things, right? And for everybody, that's going to be a little bit different. But the key, and this is what's really important, is that when you're working to optimize somebody's health,
Starting point is 00:16:38 it's not likely to happen. It's not going to happen overnight, okay? It's going to happen six months or a year later if they can stay on a path, right? So you need to give them things along the way to help them so that those bottlenecks are addressed. Is the bottleneck energy? Is the bottleneck focus?
Starting point is 00:16:55 Is the bottleneck sleep or stress? If you work on those bottlenecks along the way, then it becomes a lot easier. And I found the biggest two bottlenecks in the world, for me as a clinician, are energy and anxiety. I don't know about it because people want more energy
Starting point is 00:17:11 and people don't want to be less anxious, right? And if you can optimize their energy, you can make them feel better right now so that they have more capacity, more long term, to do the things that you want to do, like change their diet, walk around the block even,
Starting point is 00:17:24 or just do something slightly different about their stress. But if they don't have enough energy, they can't do it. That's right. And having energy is the biggest currency that we have, right? And we're supposed to make,
Starting point is 00:17:34 so we make ATP our energy currency in the body, We make about 150 pounds of that every single day to maintain our energy demands. But it's very difficult for us to do that because most of us, as I mentioned earlier, are not able to do it anymore. 94% of US adults don't have enough capacity. The biggest example that I've been thinking about recently
Starting point is 00:17:51 is black and white thinking. Our brains are the number two place that we have the most energy needs. You guys know the number one place? Is it liver, muscle? Reproductive hormone. Oh, yeah. So eggs and sperm have the most mitochondria per cell.
Starting point is 00:18:05 Oh, God. Well, that makes sense. Yeah, yeah. That makes sense. Yeah. And right after that is the brain, right? Okay. So if you're trying to think in like a nuanced sort of way, that takes a lot of energy.
Starting point is 00:18:14 That's why we're also polarized. We love to be like it's either, you know, black or white. There's nothing in between because energy demands for a nuanced kind of thinking are very, very challenging. Well, take us then to metabolic health or mitochondrial health. I mean, you hear this a lot now in social media. Yeah. What are we talking about? And why is this even a big deal?
Starting point is 00:18:34 I think that's the way of what we're seeing, right? is because metabolic health is mitochondrial health. So people hear the word metabolic health, or that term, what that really means is that can you make energy effectively and can you manage the stress of making energy? So you guys know that we eat, especially fat and carbohydrates, because we need the electrons on those particular macronutrients to be processed by ourselves in this part of the cell called the mitochondria
Starting point is 00:19:02 to help us make energy. Okay. So we need to be able to make energy, right? And so that's not an easy thing for many of us to do anymore because along that process of taking our food and bringing it down and bringing it into the mitochondria. There's a lot of steps along the way, right? There's the citric acid cycle, which is how breaks down the food and then has things like NADH and FADH, which are these electron carriers that bring electrons into the mitochondria and they go into something called the electron transport chain, which has four complexes aptly named one, two, three, and four where the electrons have to flow through. And that and then as they're doing it you make this gradient of protons, hydrodinions, and then you have to have oxygen come in and become the final electronic sceptor. This is all happening, you know, millions of times a second for all of us right
Starting point is 00:19:46 now. We have quadrillions of mitochondria in our body. It's like a huge amount that we have. And not only do we make energy, we make this ATP. We do it by allowing this gradient of protons coming back down. It's a 6,000 RPM motor that's in our cells, the ATP's
Starting point is 00:20:02 engine. It's a making energy. And then we make energy ATP, but we also make carbon dioxide, you know, which goes back to the plants and then give us oxygen, right? That's the goal. And we make, we need to make water and we also make what are called reactive oxygen species or free radicals. That's great. If we have too many free radicals, though, the system starts breaking down. And so metabolic health is, do you have the capacity to make energy effectively throughout that whole process that I just went by very briefly? And then do you have also the capacity to manage the stress of making energy. And 94% of us don't have that capacity anymore. Yeah, so compare the 94 to the top 6% like and compare it from the perspective of somebody,
Starting point is 00:20:46 the average person who's like, I want to lose a bunch of body fat, I want to be in shape. What compare those two groups, like what is happening on like a cellular level as far as like their ability to have success? It's their resilience, right? Because everybody's going to have stress. Everybody, even the people that are in top 6%, of course, they're going to have stress, but what they have is enough capacity to manage both the energy production and the detoxification side of things. And what happens over time is that the detox side of things, especially, gets really, really clogged up. And if that happens, the whole system starts breaking down. And the biggest reason for this is actually insulin resistance. So people have high blood
Starting point is 00:21:21 sugars. Sugar is one of our substrates. It goes into our mitochondria helps us make energy. But it also, if there's a shit ton of it, you're also going to make more waste products, make more reactive oxygen species. And then what happens is that the mitochondria get overloaded with these waste products because you don't have enough, what do you need to balance this? You need antioxidants to do this.
Starting point is 00:21:39 Things like glutathione and vitamin C and alphopoic acid and things like that, which over time get depleted. And then you get into a place where you can't actually manage the amount of energy that's coming in. And so the mitochondria start actually doing the opposite, actually making less over time.
Starting point is 00:21:53 And so you know this. It's not something that happens overnight for most people, but they're insulin resistant, they're fatigued all the time, They feel like they're inflamed all the time. Like they can't lose weight. Their brains foggy. They have mental health issues.
Starting point is 00:22:07 These are all mitochondrial issues at their base. And the question is just what, right? You have definitely insulin resistance being like one of the major reasons. The other one is a big one, which is sympathetic activation, always being in fight or flight, always feeling like your brain is on instead of having that parasympathetic side of things. Because if you're always on, you're always releasing neurotransmitters and hormones like cortisol that are stressing the system too. So talk about now this is 94% of the people. And you get news from the doctor, you're not healthy or what about that, or you're recently motivated because you, whatever reason, I feel like, I need to make a change in my life.
Starting point is 00:22:47 And so I cut calories. I start hitting the gym five days a week. I'm pushing, sweat my ass off. That person ends up struggling. So explain why that is. And I feel like this align so much with the car. conversations that we have in this podcast all the time, and we get a lot of shit for, like, telling people to do less. Yeah. Yeah. Yeah. Well, I've been calling it the sympathetic spiral of
Starting point is 00:23:09 doom for this particular reason, because people think they need to do more to get better as opposed to doing less. Right. And oftentimes, it's those people that go to the gym and then they crash for like three or four days after they went. Or they go into a sauna and they can't move for five days afterwards because their body's already under such sympathetic dominance, you know, that fight or flight, that running from the saber-toothed tiger thing. We always say in medical school for some reason. I know why we always use a saber-toothed tiger. Who thinks about a saber-toothed tiger, but we do.
Starting point is 00:23:40 Anyway, but, you know, that's what culture rewards, right? We all reward that hustle. I grew up in New York and, you know, the hustle that never stops kind of deal. And in medical school, we had shirts that said sleep is for quitters, right? Because it was in medical school. I mean, I told you about my rotation to shock trauma, right? 30 hours every three days. It was intense, right? And so we reward this stuff. But then what's so interesting is that as a clinician, you think people would realize when they're in this state,
Starting point is 00:24:09 but they have no idea. Right? They have no clue. They think that, oh, I just need more stimulants. Or like, oh, I just need to do the gym more. Like, I need more coffee, right? Or whatever. But then they realize, like, they do more and more, but they're not seeing any benefit, right? And so a big part of this actually is like, you know what? You actually have to calm down your nervous system without telling them to calm down. We talked about this. Right. You don't tell somebody to calm down because that doesn't work, right? But if you say, look, if we just downregulate your nervous system a little bit, throw you back into parasypathetic, everything else is going to get easier, you know? But that's, it's a conversation and then
Starting point is 00:24:42 it's giving them the experience. But the key here, and this is really important, is that when you're trying to down regulate somebody's nervous system and calm them down, if they don't have enough cellular capacity, they're going to crash, right? Because you decrease their nervous system capacity. So you're trying to get them to relax. Which was keeping them just moving. Just getting them, keeping them alive, basically.
Starting point is 00:25:02 And being able to function the way they were. I had a lady just a couple weeks ago. She was like, I was dealing with molds and lime. My doctor gave me some stuff to calm me down and I just went, bam, right? She crashed, right? Because that was keeping her. And so many of us out here,
Starting point is 00:25:15 this is the same thing. This is what's happening now, right? Is that we're just able to stay on this sort of train. And then if you, you know, if you start taking the brakes off without giving enough mitochondrial support, This is where the methylene blue actually comes in a lot, right? Because that's what had been, like, one of my biggest levers recently.
Starting point is 00:25:30 It's like if you can give them the support while you're taking the break, we're starting to put the brakes on, then that's the key. We have a term that we call them cortisol junkies. Yeah. That's that, and this is really hard to communicate to a person that's in this state because they get this immediate reward from the high stress. Try telling somebody who's here where you're describing who just did their circuit training class, and they get that rush afterwards of completing it and that adrenaline and they go like and then try being the person who's trying to tell them that's not good for you like you piss off I know how I felt right afterwards it's really difficult to communicate that I'd love for you to get into methylin blue like the history of it we talked about this you know tongue and cheek like where who is the first person to realize that die had these types of benefits to it you know for the mitochondria like how did you get uh how did you find your
Starting point is 00:26:25 way towards it. So it's a crazy compound. It's very blue. It's been around a long time. But it's absolutely a huge bridge in the work that I do because it helps right now with the mitochondrial function that we've been talking about. It helps with energy and detoxification at the same time. So I like to tell, I like to say that our cells are like gasoline powered cars. We make ATP, but we also make that carbon dioxide, not a waste product, I promise, but people will think about it out that way. I have friends that get very angry if I call it a waste product. And then water, and then, of course, there was reactive oxygen species, right? That's what our cells are making on a regular basis.
Starting point is 00:27:00 But methylene blue comes in. It helps with the energy production side, and it helps as detoxifying at the same time. So it works with energy and detox at the same time. It's called a redox cycler in that way. So the history of it, in the 1870s, 1-870, so a long time ago, it was developed as a textile dye. So if you wore like Levi-Strauss genes,
Starting point is 00:27:21 your genes were dyed with methylene blue. But at that time, you guys, if you had like a cellulitis, like an infection on your leg, you would die, right? Because there was no antibiotics. There is no antimicrobals available, right? So they were looking for compounds out there that could treat these kinds of infections because nothing existed. And so they realized that methylene blue, it actually got the name of a magic bullet at
Starting point is 00:27:44 the time, could treat pathogens, could kill pathogens at high doses, but it would not harm the normal, the human host, right? And that was like the best thing ever that they could find. either they could find compounds that would kill you and kill the pathogen too which that's not very helpful or they wouldn't be strong enough to be an antimicrobial, right?
Starting point is 00:28:05 So methylene blue was the first drug registered with the FDA in 1897. Oh no shit. Yeah. So it was a very nascent FDA and it was the first fully synthetic drug too so it's not something that comes from nature directly.
Starting point is 00:28:19 And that also gives it a little bit of like some controversy in the world of medicine and alternative medicine, right? even with my dad, and he uses it in clinical practice. But I like to remind people that synthetic things are not necessarily bad for you, just like natural things are not necessarily good for you. Like you can forage for the wrong mushrooms and die. Well, I think the value of natural things is,
Starting point is 00:28:39 they have a long history of being used. This is a synthetic that's been used for over 100 years. Yep. But didn't like leach into somebody's wound? Like, how did this, like... So they were doing cellular testing on malaria, actually. And they found that malaria spous. Specifically, you know, us white people going down to Africa and getting malaria, you know, we would die, right?
Starting point is 00:29:00 And so this particular compound, methylene blue, could give it very high doses of methylene blue, and it would kill malaria. And they saw it in cellular culture. Oh, wow. And so then they realized, well, what else can it do? So between 1897 and 1950 or so, it was like the premier antimicrobial. And by the way, it still fucking works. But it doesn't, it wasn't as sexy because you had penicillin and other. drugs that came out in 1950s, which is very important.
Starting point is 00:29:27 By the way, if you go to the hospital now, there's a condition now that they'll give you intravenous. What is it? It's called met hemoglobinemia. Okay. And this is a particular condition where your red blood cells can't carry oxygen. Okay. It's typically because you've had an overdose or poisoning.
Starting point is 00:29:44 Like you guys know, like the huffer people, like huffing glow or huffing paint, that has something called sodium nitrite in it. And that is colorless and tasteless, but it actually prevents you from carrying oxygen. on your red blood cells. So methylene blue is the antidote for that, for medhemogloamemia, and it's also the antidote for cyanide poisoning. So if you're going to Russia anytime soon,
Starting point is 00:30:04 you know, make sure you're bringing it with you. Because what it does, so cyanide actually destroys part of those electron protein complexes that I was talking about. It destroys complex four. And so if you get methylene blue on board, though, there's all these kind of ninja moves on your electron transport chain
Starting point is 00:30:21 to bypass blockages or bypass areas. areas that aren't working. That's what makes it so powerful is that because so many people are walking around with mitochondria that don't work well, especially Complex 1 and Complex 2, which are the main complexes that take electrons from your food. So if you've had chronic infection, if you know, you're diabetic, if chronic stress, pesticide exposure, so many different things can affect those first couple of complexes and affect the capacity for your energy production to happen.
Starting point is 00:30:48 So short story with Methylene Blue is that between 1897, 1950, fantastic anti-microbocer. It only had one, you know, major side effect, which you guys have all experienced. Blue pee, yes, blue urine. And so there was actually even stories, songs in World War II. If you were World War II and you were shipped off to the Pacific, you were taking methadne bupropylactically to prevent fungal infections while you were in the jungles of some of the tropical islands in the South Pacific.
Starting point is 00:31:17 And it was calling, they said going blue in the loo, right? With all the English, all the English people, going blue in the loo. So, but in the 1950s, when antimicrobials came around that were prescribed, it became less used in that way, although it works fantastically well as an antimicrobial and still does. And I use it that way now, especially for urinary tract infections, actually, because methane blue makes your urine blue concentrates in the bladder. It breaks up biofilms. It's an antimicrobial at high doses. But at lower doses, around like four to about 25 milligrams, it's a fantastic mitochondrial support. And we know that from the last several decades of research.
Starting point is 00:31:54 There's a researcher at the University of Texas, Austin. His name is Francisco Gonzalez-Lima. And he's done a lot of work on Alzheimer's models, traumatic brain injury, stroke, and others looking at how methylene blue concentrates in the mitochondria and optimizes mitochondrial function. And it does this very effectively and very, very quickly.
Starting point is 00:32:12 It's not like you take methylene blue and you wait a month for it to start working. It starts working. That day. Yeah, it should be within three to five days of taking it. If it doesn't work at that dope, you go up on the dose, right? And so the higher dose is like a milligram per kilogram,
Starting point is 00:32:25 which is like 50 to 70 milligrams, or a little bit higher, maybe after 2 milligrams per kilogram for an acute infection. Like, that is a fantastic way to use it. But for the most part, I'm using it at lower doses, four to 25 milligrams on a regular basis.
Starting point is 00:32:39 For the whole spectrum, for people that are super sick and need that bridge, that support, but also on the endurance side because it increases aerobic capacity. It works, can work just like oxygen in your cells too, so you can maintain aerobic capacity for longer. And the first time I realized this,
Starting point is 00:32:55 I was working with a patient, this Southern lady, I can't do her accent, but she's something, Alabama. And she's like, Dr. Scott, I can't stop working out with this stuff because it's so great. I'm like, well, what's so great about it? She's like, well, I can maintain my heart rate up
Starting point is 00:33:05 for longer without having to stop. And I work with a guy that did the Leadville race, the Ultramarathon where I live in Colorado, and he cut three hours off of his time using Methylene Bluth, 32 milligrams every four hours. So how are you measuring the success of the delftainment? So like you decide how do you figure that out and then we know like oh this is working well we don't need to go up or like how do you feel? So a lot of it's going to be how you feel, right? But then you can also look at metrics like heart rate capacity like you maintain like heart rate for longer if you're doing aerobic work. There's some studies that we did on dog specifically looking at lactate threshold. And so that you reach your lactate threshold later if you have methylian blue on board because it's able to maintain aerobic capacity for longer. So a lot of it's going to be subjective, which would which means that how do you feel when you're doing certain things and then looking at various. markers. But like what's weird about it is that you can give somebody methylene blue in the
Starting point is 00:33:54 morning and they sleep better at night. Well, why, right? It's because they're getting better mitochondrial support during the day. And then you see their HIV go up at night as well when they're sleeping. It's the same deal because you can see how when you give more mitochondrial support, the system starts being able to calm itself down because it's now like, okay, now I'm having enough support here. It's not trying to fuel with stress hormones and stress all the time. Right, exactly. And so the mitochondria able to relax. Like the, there's this thing called the cell danger response. which you guys have probably heard of, where the whole system goes into this sort of shut down
Starting point is 00:34:25 hibernation mode, especially the mitochondria, if there's too much stress in the system, your cortisol people, right? What happens instead of the mitochondria making more energy, they actually make less. But if you can flip it out of this all danger response, then it starts being able to make more.
Starting point is 00:34:39 And that's why, like, I've been shocked over the years. Like I had a guy, a colleague in mine, he's like, I've had anxiety on my life. I took Bethlehem blue and it went away. And I was like, huh, well, what's up with that? really because what his anxiety really was a representation of was mitochondrial stress, right? And when we're giving him more support, then his mitochondria are able to like flip back over into a more healthy way of optimizing energy production.
Starting point is 00:35:02 Now, there's a lot of things that are marketed to us today about mitochondrial health. An example, red light therapy. Yeah. Is there added benefits of pairing it with this? Like, I mean, so like, what would, what, if I, you were giving me all the things to do that, what would a stack or all the, you know, what you would prescribe to me. Yeah, all the things.
Starting point is 00:35:22 There's lots of things that can be there. What I would say is there is a significant synergy between methylene blue and red light. That's been well described because methylene blue can donate electrons basically help with energy production at all the complexes, but especially Complex 4, which is called cytokromoxidase.
Starting point is 00:35:38 And red light therapy, about 680 nanometers, well established as donating photonic electronic energy to Complex 4 as well. And so that combination is very powerful. So you can take your methylene blue 45 minutes or an hour later, 40 minutes to an hour later, you go outside in the sun.
Starting point is 00:35:55 You know, red lights in the sun, everybody don't have to have a panel. Or you can go in front of your panel if you have one too. That's a great synergy. Now, at higher doses, like you can use that as a compounding for infection as well,
Starting point is 00:36:06 especially for viral infections. So you give your methylene blue higher doses, you go out in the sun. This is what I was doing four or five years ago without telling anybody that I was doing it. and seeing significant benefit. And a lot of my clinician, you know, colleagues were too.
Starting point is 00:36:19 So antimicrobial, also for viral infection. Yeah, antiviral too. Wow. Okay, now, methyl in blue is also an MAO inhibitor. Yeah. It's actually a quite strong one. So let's talk about that for a second. Yeah.
Starting point is 00:36:30 So MAO is a monomene oxidase inhibition. Yes. So what that means is that methane blue prevents a breakdown of noraphenephrin and serotonin, and it higher doses is dopamine. Okay. And so that means there's more of that around. But it's dose dependent.
Starting point is 00:36:41 So lower doses of methane blue are going to do a little bit. Higher doses are going to do it more. But it's something you have to do it more. but it is something you have to be aware of. Yes. You have people that are on things like SSRIs and, you know, Saratogenic re-uptake inhibitors.
Starting point is 00:36:52 These are antidepressants. Yeah. You don't want to combine them. So you don't typically want to do that. The risk is very low to actually do it, but I recommend doing it with a practitioner. Okay. The risk that they talk about all the time,
Starting point is 00:37:01 something called serotonin syndrome. Yep. Which is not something that any doctor has really ever seen in their clinical practice. Happened to me. No. You did so south. Yeah, that was stupid.
Starting point is 00:37:10 I did methylin blue with Tessophencin, which is a peptide, well, you could buy it as a peptide, which is a norapinephrine serotonin dopamine re-uptake inhibitor. Okay. And so, and I just started sweating like a maniac.
Starting point is 00:37:25 Okay, you started sweating. Like real bad. Yeah. He went to hospital. Like drenching. And so I went to hospital. So I'm like,
Starting point is 00:37:30 oh, is this serotonin syndrome? It might be. So I went there, had the shivers the whole thing. And then I, it was a few hours later. I was okay. How much muthling blue do you take?
Starting point is 00:37:38 I've probably, but the testofensin was, I don't remember what that happened. Must have been a pretty strong. You did a high dose of testofensement. remember you were upset how high of a dose you were. That's right, yeah. That must have been it, because usually,
Starting point is 00:37:47 the only time I've, the only studies that they've shown causing serotonin syndrome with methylene blue have been IV methylene blue. Oh wow, which is a high dose. Yeah, which, you know, it doesn't have to be high, but it gets the body really, really quickly, right? And then when people start taking methylene blue, even at the low doses, one of the things that most people
Starting point is 00:38:03 say that they feel like slightly funny, like a little bit, like off, a little bit different, that's usually because of the neuropine and dopamine doesn't happen until much higher dose, of methyline. Yeah, but yeah, that was, again, that combined two things I put. So this is just where,
Starting point is 00:38:18 because it works. It actually does work. Yeah. And so you want to always be careful with things that work and combining it with other things. Yeah, but I have the integrative psychiatrists that are weaning their patients
Starting point is 00:38:25 off of SSRIs of the world, SNRIs and using methylene blue and stuff. I was just going to say so, because here's one of the other things, and I don't even know if we can necessarily talk about this, but I know a lot of people who use methyl in methanol blue as an antidepressant because it lifts their mood.
Starting point is 00:38:39 And what is mental health issues like depression really at their core? It's a mitochondrial issue, right? I mean, we know this. It's a gut issue. It's a mitochondrial issue. You have all these books that, like, fix your gut and your depression goes away.
Starting point is 00:38:50 Optimize your diet or start exercising and depression goes away, right? So there is a, there, we know 100%. Like when I went to medical school, I learned that if you were depressed, it was a serotonin deficiency. Yeah. And that's completely bullshit. There's no evidence at all. But, you know, actually there's more evidence that there's a gaba urgic aspect to hear.
Starting point is 00:39:08 So GABA is our primary breaks of the brain. And GABA deficiencies associated with depression. but low serotonin levels are not, right? And so we know that the mitochondria are the big part here, right? So understanding how you can optimize mitochondrial function is key. Understanding why the mitochondria under stress is also key. Like, is it toxic exposure? Is it synthetic domenance?
Starting point is 00:39:28 Is it medications? Is it medications? Like there's all these other things that it can be, right? So you have to think about the roots. We talked about the root causes. But then if you just focus on optimizing mitochondrial function first, and the additional benefit with methylene blues, you do have some mild increase in serotonin and norophenephrin as well, right? But it is dose dependent.
Starting point is 00:39:48 How does it compare if you, and I know like it sounds like you use this to get the client going, jump started, and then of course nutrition exercise is key, right? For sure. Now how does it compare though head to head with that? Just a better diet and strength training because we know that's obviously incredible for mitochondrial health. So how does it compare? My goal always with people is like, let's get you on some methylene blue if you need it now.
Starting point is 00:40:10 and then over time, as you optimize your diet, as you optimize your lifestyle and your exercise, you need it less. You know, I was talking to our mutual friend Thomas DeLauer just a couple days ago. And I was like, he takes it two or three times a week, right? When he has like a bigger day, more stress, you're traveling.
Starting point is 00:40:26 If you're well optimized, you don't need to take it every day. But if you're traveling, like, let's talk about an airplane, right? Yeah. Airplane, you're pressurized on a plane to 8,000 feet above sea level. So as soon as soon as that cabin door closes, you get tired. You want to take a nap, right? because you just became hypoxic all of a sudden. Yeah.
Starting point is 00:40:42 And I'm, you know, for me, when I live in Colorado, it's glorious getting on an airplane and coming to the other places that I go because it's mostly sea level. Yeah. So my, you know, my ring loves me, right? Because I'm always, you know, at sea level and I have 21% oxygen in the air.
Starting point is 00:40:55 Where I live, it's about 17% oxygen in the air. When you're on an airplane, you're about that too, about 17, 18%. And so that's a hypoxic stress almost right away. So taking methylene blue before you're on an airplane is like transformative for people, right? Because even if you're mitochondrally healthy, right that's still significant stress so you use it as like a pre travel stack that you can use
Starting point is 00:41:16 it is transformative oh wow so all of my patients it's a great hack that's so great i'm going to use that because i travel we all fly a lot quite a bit for the company and i always don't feel good from on a plane and so and i've never thought to use methylin blue beforehand yeah before and during depending how long the flight's going to be so i have people dose every it's the half life's about four hours so if you have a flight that's 10 hours you're dosing every four hours while you're on the plane You just want to modulate your dose depending on sleep. Yeah. And then you also want to try to, you know, meet the time zone that you're going to go to.
Starting point is 00:41:46 But then you can also use gabergic things. You know, we have other things that we use to help people. What you're saying about mitochondria, I think now lots of data supporting this. So people might not even aware, but there's all these studies now they're coming out like creatine. They're showing it's got antidepressant effects. Why? Because it helps with ATP production. We know a ketogenic diet sometimes has its effect, not because there's magic.
Starting point is 00:42:08 the diet, but because producing ketones is just a cleaner, I guess, for lack of better term, way of producing energy. So if you've got kind of dysfunctional mitochondria, suddenly you feel like, oh, wow, it feels so much better. Well, it's because you just switched energy sources and you have something different. So, yeah, mitochondria, this is, this is like, it looks like medicine is kind of moving in this direction. Yeah. Where they're all looking, okay, what's, what's going on with the mitochondria? It's, it's called cellular medicine sometimes. It's called mitochondrial medicine, but it's absolutely happening. Because we used to think, you know, these might as a My mitochondria, you know, when I was just, my daughter is 15, she just took science and she learned
Starting point is 00:42:43 about the cell, and then you have a nucleus, and you have the mitochondria, you have the gold ubodies. There's just one mitochondria in that cell that you learn about. Then you learn that there are some cells like we were talking about eggs and sperm that have thousands, neurons, thousands of mitochondria per cell. And they're not just making energy. They are, there's a whole new world of talking about like mitocentric medicine you're going to be hearing. Oh, wow.
Starting point is 00:43:03 And it's going to be all about the mitochondria are these gating and sensing organs in your, you're in your cells. Your nucleus? Yeah, they're kind of important, but they're not as important the mitochondria is what we're actually. I mean, obviously it's where all your DNA and everything. But then also,
Starting point is 00:43:16 as Dr. Ted likes to always remind me, like, where is the brain of your cell? It's not your, not your nucleus. It's actually the cell membrane itself. Yeah. The cell membrane itself is sensing everything. I have to decide what to let in,
Starting point is 00:43:27 what not to learn. Exactly. So the cell membrane. So that's why we talk about phospholipids. We're talking about, you know, oxidative stress. Because you can see all signs of this in the lipid membranes as well.
Starting point is 00:43:36 Then, of course, the trans fat arguments. and all that, thankfully, those are gone for the most part now. What's the role of mitochondria dysfunction in cancer? It's a big one, right? Because if you think about cancer, cancer is an end-stage process that's happened because of poor terrain or poor foundational health, right? If your immune system optimized, like, we're making cancer cells right now, all of us,
Starting point is 00:43:57 every second of every day. But our immune system knows, most of the time, amazingly, to get rid of those cells, right? But cancer cells are just trying to protect themselves. This is a crazy thing. There's all these ideas of, of you guys sort of like the mean gene, like Richard Dawkins stuff, but like the idea is that all of our cells
Starting point is 00:44:14 are really just trying to protect themselves and do what they're supposed to do. And if they need to protect themselves because there's toxic exposure because there's sympathetic activation, they're going to do what they need to do to try to survive, right? And that's what cancer cells are doing, right?
Starting point is 00:44:26 And so, and a big part of that is the mitochondrial aspect of this, right? Because mitochondrial function, if that starts going down, the whole cell starts going down too. Because if you can't sense how much energy needs to, to be made. You can't sense what you need from a resources perspective. You can overcompensate
Starting point is 00:44:42 or you can undercompensate, right? And this is the thing about, you know, what mitochondria do is that you make new ones all the time, but you're not making them like de novo. They're actually being mitochondrial efficient. So you're actually making new ones out of the ones that you already have. And so, yeah. So it's like making a photocopy of a photocopy. Exactly. And they start to get worse over time. Yes, exactly. Wow. Wow. Did you, did you work with hyperbaric chambers start your kind of fascination with mitochondrial health? It did actually. Yeah, 100% Because I realized what you're doing in hyperbaric environment is your flooding body with a huge amount more oxygen. And that sounds great in principle, right?
Starting point is 00:45:15 But what that does is revs up your capacity and make energy, if you can. And also revs up your capacity to need to detox because the way methling, the way, excuse me, the way hyperbaric therapy works is by creating a huge amount of oxidative load, huge amount of reactive oxygen species in the system. But what if you can't tolerate all that, right? The idea with all that ROS is that you're creating an impetus for stem cells to get released, the immune system to get activated, to kill bugs, to do all these good things, to decrease inflammation. But if your system can't tolerate that, then you're going to be in a world of hurt,
Starting point is 00:45:46 or you might get some benefit, but you're going to go back to the same way you felt before. This is what I kept seeing in hyperbaric medicine. Like, I actually got disinvited from a conference back in the day because the title of my talk was going to be, please don't put them in the chamber. And I love hyperbaric medicine. I think it's fantastic.
Starting point is 00:46:02 But it sounds like it's far more beneficial for somebody who's metabolic healthy than it is for somebody who's not. Right, or to at least try to optimize for like three or six months to get the foundation on board. And that's where that health optimization medicine became a huge piece for me because I was, I would seeing people and they weren't getting better. Like, you should get better. Like you have an infection. I'm treating it with hyperbaric therapy.
Starting point is 00:46:21 Like, they should get better, but it wasn't. Like, or they were getting a little bit better, but then they just get worse again and relapse. And I was like, well, this came down to understanding cellular metabolism, understanding energy production, detoxification. And then how could I help them? Well, I could use this foundational framework called health optimization medicine that takes three or six months to get them better, work on that, then get them on some methylene blue,
Starting point is 00:46:40 which would be really great as a support. And then also working on optimizing their nervous systems or down-regulating their stress response. Because this is the other thing, right? I actually just learning about this a couple of days ago where there's some of the antidepressants actually are mitochondrally dysfunction. They make the mitochondrial dysfunction more.
Starting point is 00:46:57 Because I found out, like, early on in my career and using hyperbaric therapy, that some people on certain antidepressants just would not get better. Just would not. And I was like, why is it on Symbolta, you won't get better on using hyperbaric therapy was because it was destroying mitochondrial function, right?
Starting point is 00:47:12 And so I found it over the years that if you can really focus on helping people now, you know, and then giving them a ground game, that I often say get 60 or 70% better first and then let's get you into the chamber to get you that maxed 30% more. Got it. There's other reasons.
Starting point is 00:47:28 If you're doing performance or recovery, there's other reasons too. Like you can just go into the chamber tomorrow or if you have an acute issue. But in essence, my practice is kind of developed like, okay, hyperbaric therapy is great, but if you want to see long-term benefit, you need to get 60 or 70% of the way there anyway, right?
Starting point is 00:47:47 And then if we do that, do you really need to be in the chamber? Then we can have that conversation, right? I use hyperbary therapy all the time still. But what I'm using on my ground game for people is like, okay, let's optimize. Much more complete picture. Yeah, yeah. Were you guys one of the first ones at proscriptions to use methyl in blue or to work with methylin blue?
Starting point is 00:48:04 We were the first company to make a commercial product with Methylene Blue back in February of 2020, so just about six years ago. Wow. And it exploded. Yeah. And it exploded. You know, what's so interesting about it is that before us, you had to go to like a chemistry company or somewhere, you know, to get it. And it was very difficult to find good quality stuff. So we were the first, and it took us about a year longer to launch the company in 2020 than we anticipated.
Starting point is 00:48:29 It's because that long to find a good source of it. Really? The problem with Methylene Blue is that when you make it. it's often, it's made in the lab, and it can be contaminated with heavy metals, like lead, mercury, cadmium, and arsenic. Is that often the case? Unfortunately, yes. Even, so if you look online now, you can find it everywhere.
Starting point is 00:48:48 We were the first company, the only one in 2020. There was like six companies in 2024. Now there's over 100 companies that are making it now. But the problem is that the quality is all over the map, and it's not very good. And so there's something called USP grade. So if you go online now, you go online. line to Amazon. I don't recommend you buy any supplements on Amazon, but especially methylene blue. There's a lot of counterfeits. So much counterfeits. Which is crazy. Yeah, it's creating millions
Starting point is 00:49:12 of dollars with, so I always tell my patients do not buy your supplements on Amazon. But in any way, so methylene blue specifically, this USP grading it's called. Like that's supposed to be pharmaceutical grade. But the problem with that is that people don't eat, they just put that on the label. And then we've tested a lot of this stuff as well. It doesn't meet USP grading. And that means it's more contaminate with heavy metals. And the liquids out there are probably the worst defenders because their potency is nowhere near what it says on the label. Like one of my biggest pet peeves is that, if I say, Dr. Scott, I've been taking methylene blue 10 drops a day for a week or whatever. And I feel like, I'm like, well, how much you've been taking? I'm 10 drops a day. I'm like, well, how much is
Starting point is 00:49:49 that? I'm like, what are you telling me it doesn't work? What are you telling me it's making you? And then what are you taking, right? And then so liquids are really difficult because it's like a milligram per like dropper. You don't know exactly how much it is. And then it gets on your countertop and you almost have your wife try to divorce you and I've I've I've so the key this is a good trick if you get methylene blue on a countertop it does stain buffered vitamin C oh wow this is save my marriage at least three times in my laundry on my in my sink so it does work but the challenge is like finding good stuff is really difficult sal and I found we've tested a bunch of stuff across
Starting point is 00:50:26 Amazon stuff pharmaceutical stuff that you can prescribe and Scott I'm not just saying because we work with you guys. Actually, this is one of the reasons why we work with you guys. I've tried three different, separate from transcriptions, so three other methyl and blue providers. And yours was the best, has been the most consistent best experience. So it's got to be that. It's got to be that I wasn't getting either the right dose or there was some other stuff in there. Yeah, one of my favorite stories is a guy a couple weeks ago, actually a couple months ago now. He's like, yeah, Doc, I bought this methylene blue from a source that it says with many United States, and it took three weeks to get through customs, you know,
Starting point is 00:51:02 the times. And this is the thing. If you're buying it on Amazon, it's so funny how things come back like full circle, right? Because early in the pandemic, about six months in, there was this article from the New York Post. It said biohackers drinking fish tank cleaner to reverse their age. That's because. Great clickbait. Well, because Methyl and Blue were killed.
Starting point is 00:51:19 You get Metham Blue's in Fish Tanklater. Yeah. You don't want to drink Fish Tank Cleaner. Please don't win a Darwin award, everybody. That's very highly contaminated with heavy metals. But it was a great clickbait headline. That same paper. eight months ago, did a whole article just espousing the beauty of methylene blue and had an affiliate
Starting point is 00:51:35 relationship with one of the shittier ones on Amazon. I was like, of course. That's how it's going to go. Is it antiparacetic as well? Yeah. Anti-parasitic. It's antimicone. It's anti-pricid. So we use it for people that have parasites that have dysbiosis in their gut, that have, you know, overgrowth of bacteria. How does it kill? Now, how is it anti-parasitic and antimic? Do they just not survive the electron transport? No, it's actually a little bit different. So you guys know hydrogen peroxide? So we can buy it at the store, but our cells make it as an antiseptic. It's housed in a part of our cell called the lysosome. And when we have an infection or if the cell is trying to kill itself because it's under stress
Starting point is 00:52:12 and it's better to sometimes die than to try to survive, it'll release hydrogen peroxide. So Methylene Blue releases hydrogen peroxide to help kill these kinds of things. And what's cool about it actually is it doesn't work like a nuclear bomb as an antibiotic or an antimicrobial. Like if you take, you know, a moxacosilin or augmentin or something else, like these are nuclear bombs to your gut. They kill everything. Yeah. Yeah.
Starting point is 00:52:33 And what methane is more selective than that. It doesn't do it. It really does have a more selective capacity. So you can give it in the acute setting and not worry about causing that nuclear bomb kind of picture in the gut. But, you know, for the most part, we're using it lower doses. Like we're using that four, eight, 16 milligrams. Eight is the, for me, the sweet spot. That's where I find where I feel the best with it.
Starting point is 00:52:56 So I was just going to say, like, so you use your fish cleaner and then your horsy-womber. It was that time. It was that time, guys. But so what we do with quality is that we get our methylene blue from a manufacturer in Japan or Korea, South Korea, for those of you who are wondering. I'm not North Korea. I have my, our CEO boomer, he's married to somebody from South Korea, but they just say they're from Korea. And I was like, wouldn't they say South Korea? I'm like, no, wouldn't it be obvious that they're from South Korea?
Starting point is 00:53:24 Yeah. I didn't really think about that. Anyway, so we get it from Korea and Japan, and then when it comes in, we get it with a certificate of analysis. It has USB grading. But then we test it again. So the problem in the supplement industry in general is that they're trusting. You talked about creatine earlier.
Starting point is 00:53:41 Like you hear about that creatine scandal? No. Cretein Ghetto. Oh, yeah. Oh, yeah. Cotene. Oh, yeah. Nothing.
Starting point is 00:53:47 They just eat candy. Yeah. It came with a C of A from the manufacturer, certificate of analysis, that said creatine in the gummies, right? So you have these companies because we have to regulate ourselves in this world as you guys know, nobody else is doing it. That they just take that C of A
Starting point is 00:54:03 from that other company from another country. I don't care if it's China. I mean, things getting from China is fine. If you have a C of A that is optimal and you test it again. So with all of our products, we take at that next level and we really say, look,
Starting point is 00:54:15 yes, this is a trusted manufacturer, but we trust and we verify. And we've had to even throw out thousands of dollars worth of stuff from our trusted manufacturer over the year. Do you need to take a break on methyl in blue? Or is it something you take daily or take it every other day?
Starting point is 00:54:28 Like, what's the best way to use it? It depends on why you're using it. If you're using it for a bridge because you have chronic fatigue and you're, you know, you have autoimmune conditions and you have severe mitochondrial dysfunction. You have long COVID or other kinds of conditions where you have, you're in a pretty bad place or you're in a pretty significantly compromised place. Then taking it every day for a little while. Okay.
Starting point is 00:54:48 Or maybe even for months can be okay. Like as long as you're keeping the dose, if you're taking about 30 milligrams or less, I usually say you don't have to take a break because it's super low doses. If you're taking over 30 milligrams a day, you usually take at least one day off. If you're taking over 70 milligrams a day, two days off a week. But it's pretty rare to have people on those doses. How would someone know when they're taking the dose that they took too much? Like, what do they feel with like, okay, I got to back off?
Starting point is 00:55:11 It's so person dependent. What I find is that what I like to do is titrate people. So like with the just blue that we have at transcription, it's in a trokey form, which is like this dissolvable lozange, which classically could be dissolved in the mouth, but it can also just be swallowed. Right. And methylene blue is very highly bioavailable, which means that you can take it in the mouth,
Starting point is 00:55:29 you can swallow it, you can use it in the IV and almost all of it's going to get in the body. Of course, if it's an IV. There's very few compounds that are like that, actually. But so with methylene blue, the way we developed in these troche forms, you can take a quarter, which is four milligrams,
Starting point is 00:55:41 and then you try that for a couple days. Try it in the morning on an empty stomach, see how you feel. You don't feel much, then go after about three days. If you don't feel much, go up to eight. See how you feel. You're like, oh, so you can,
Starting point is 00:55:52 what's your experience? And so how do you feel when you take it? Oh, sharper. I just have a little bit more energy, you know, verbal fluency is better. I use it before big interviews typically. Yeah, right. And so in your case, I would be like, okay, you tried eight. Let's try 12.
Starting point is 00:56:05 Any difference? You're like, you know what? At eight, a little bit jittery or didn't feel as, as I felt like a little bit too much, you know? And then usually it's like, usually it's an extension of how you felt when you felt good, but maybe just a little bit less good, you know? And so oftentimes it's not like a more as better kind of thing. Yeah. Oftentimes I find between eight and 16 is the dose for most people.
Starting point is 00:56:25 Yeah, if I go up to 16, it's a little edgy. Yeah, exactly. That's how I would describe it. Yeah, and that's what I feel. Like, I'm usually around four or eight milligrams, actually. When I get above that, I get on the edge of your side. But sometimes what I'll do, if it's a long day, is I'll combine it with something that's going to take off the edge at the same time.
Starting point is 00:56:41 Like what? Theanine? I use one of our other products. I use, like, our gaba urgic stuff. Okay. I use our trocom, actually. Because that one has, it gives you some anxiolytic effects of anxiety, decreasing,
Starting point is 00:56:52 takes off the edge at the same time it also doesn't make you feel tired. So I like that combination. What's in that? Because I saw you, you brought that today. What is in the calming one?
Starting point is 00:57:01 So GABA, what else? So TROCOM has something called B3 GABA. Okay. It has Kava, CBD, and CBG. Now, the thing about GABA, you guys probably know this, but GABA is our primary relaxing,
Starting point is 00:57:14 the brakes of our brain, right? It calms things down. Yeah. It's always imbalanced with another neurotransmitter in the brain called glutamate. You know, glutamate is our excited to our neurotransmitter,
Starting point is 00:57:23 and glutamate actually gets converted into gab in the brain. So that's 80% of your neurotransmission, just those two. So you heard about serotonin, noraphyrant dopamine. That's like the minority of what's going on. And the classic glutamate overload situation
Starting point is 00:57:37 is like when you go to a Chinese restaurant and have MSG and your food. And so you have, what do you feel? You have headaches, tremors, you're irritable. The problem is that most people are... What's that? I said, then you're hungry again. Yeah, exactly, yeah.
Starting point is 00:57:49 That's the word. the problem is that most people are walking around with those things. Irritable, you know, mood instability because most people are walking around GABA deficient. Gabba deficiency is associated with anxiety, associated with depression. We were talking about that earlier. Associated with insomnia, mental health issues. But if you go to a doctor, you know, like a conventional doctor, like one of my colleagues, and you say I feel depressed or anxious, they're going to give you an SSRI, right? But we talked about how seroton is not related to depression, right? But GABA is. But the thing about just, well, could you just take a GABA supplement, right?
Starting point is 00:58:24 GABA itself is too big of a molecule to get into the brain. So if you take GABA on its own and you feel great, you have a leaky brain. Wow. So your blood-brain barrier isn't that great. Isn't doing what it's supposed to do. And this correlates very dramatically with a leaky gut. So I've had patients that I work with over the years. They're like, hey, Doc, I'm taking GABA.
Starting point is 00:58:45 I feel great. I'm like, okay, let's do something about that. And because it's diagnostic, basically, if you have. but you optimize their gut, they seal it up, and the GABA supplements stop working. Now, B3 GABA is a smaller. B3 GABA is different. So B3 has a vitamin B3 attached to the GABA itself.
Starting point is 00:59:01 And B3 has a transporter. Got it. So B3. So it hitches a ride. Hitches a ride, right? And then in the brain, it hydrolyzes, it breaks apart. So you have mild amounts of B3, which is niacin and NAD, and you have GABA. Okay.
Starting point is 00:59:12 So that combination is great because now you have the GABA, which is relaxing you, but you also have mild activation. so you don't feel tired at the same time. And so you get that combination is great. And then we have Kava in there too. And so the cool thing about how we developed this is Dr. Ted is the founder of the company, this brilliant pharmacologist dude.
Starting point is 00:59:34 Well, what if we created a way to enhance the GABA system in the most comprehensive way possible? So when you think about the GABA receptor, small biochemistry lesson, I promise. It's a cool one though. So GABA itself is a, the receptor has places where things bind. It has where GABA binds.
Starting point is 00:59:48 where GABA would bind, right? But it also has other places where things bind, like alcohol, for example, or benzodiazepines like Ativan and Xanax, or sleep drugs. The problem with these separate sites that were GABA binds, the GABA receptor to wear GABA binds,
Starting point is 01:00:00 is that they can bind very tightly and enhance GABA to bind very, very tightly, and then deplete GABA in the process. So you drink alcohol, you wake up two hours later feeling like shit. That's because all that GABA was depleted very quickly, benzos, and Xanax, all these things, they do the same thing.
Starting point is 01:00:16 And so you don't want to give something that just increases the amount of gab to bind without giving a source of GABA at the same time. So he created something called an obligate pair or an obligate pair where you bind something to a separate site on the GABA receptor and at the same time give something that works just like GABA, or GABA itself.
Starting point is 01:00:33 So in case of trocom, you have nicotinol vitamin B3 GABA and you have Kava. And Kava binds to a separate site on the receptor. It makes you feel drunk, right? You guys have had Kava before, right? But Kava itself is also something that can cause tolerance and addiction just like alcohol, just like benzos, just like sleep drugs,
Starting point is 01:00:50 because it depletes GABA in the process. And so instead, what we do is you have a combination of the B3 GABA and the COBA together. So the COVA binds, and you have the B3 GABA going in. So you have this nice combination where you get no tolerance, no dependence, no withdrawal, and you can take it as needed, and you don't feel tired at the same time. What's the dosage look like for somebody?
Starting point is 01:01:12 So the COOM, the TROCOM dosing is the B3 GABA, I believe, is 50 milligrams. five zero and then you have kava which is 100 milligrams yeah and you have then we have CBD and CBG yeah so just a small amount of CBD and CBG and that that works on the endocannabinoid system the body's own internal cannabis system you guys and the there's a garran in there what is that oh so agron's in um it's in our sleep it's in our sleep formula okay so what is that agarine is from the fly agaric mushroom do you guys know the the aminemuscaria mushroom i know justin did by the way off there justin like named it right out the gates I'm like what I know he does Yeah, well, what's his name?
Starting point is 01:01:50 Paul Stammer. I've listened to quite a few of his podcast, but yeah, he talks about the association there with Santa Claus. Yeah, it is, yeah. Yeah, there's a great, if people are listening, they can look up there. There's a New York time piece on the idea that this particular mushroom, the aminita muskary mushroom,
Starting point is 01:02:05 is the reason why we have Santa Claus. Because as the stories go, in Siberia, this mushroom would grow wild, and the reindeer would eat the mushroom because they liked it, and it also made them trip balls. And then people were like, oh, what's going on here?
Starting point is 01:02:22 And then they realized that eating the mushroom itself is toxic. It's neurotoxic, but if they dried it, it would become less toxic. One of the ingredients in the mushroom is called ibotanic acid. That's neurotoxic, neotoxic, excuse me.
Starting point is 01:02:35 The other ingredient is called agrin. And agron is a long-acting on the GABA receptor. Oh. Binds to where GABA would bind. And so we combine that with another modulator of the GABA receptor called Hanokial or Hanakyle,
Starting point is 01:02:49 which comes from magnolia bark, and that combination of Hanokial plus aggrins in our formula called Trozzi, along with six other ingredients that are working on sleep. But working on the GABA system is really, really important because, again, most of us are deficient. And if we can put the brakes on for people, they start calming down their nervous system. And we talked about mitochondrial function.
Starting point is 01:03:09 The combination of supporting mitochondria with something like methylene blue short term, and then less long term if you get more optimized, and then using something that puts the brakes on, like your calm and your Z here for me, then suddenly people can feel like, oh, that's what it felt like to not always be in stress mode, right? And doing it in like a very intentional, you know, safe space,
Starting point is 01:03:30 if you want to call it that. Because when people have like, their nervous system calm down for the first time, they actually get reactive anxiety to not being stressed. Wow. You guys have probably seen this, right? Somebody's like, like working at such a high level stress-wise, and you bring them down,
Starting point is 01:03:43 they're like, holy shit, I'm supposed to be stressed, and they get very anxious. about it. So it's nice to have this link and more of like, now here, trocom, just take it in front of me. Wow. 15 minutes later, you're feeling better? This is what it feels like to not be in stress mode, right? Wow. Because it works that quickly. Because that's better used in the mouth, the trocom, because it's gonna work in about five to 15 minutes. Oh, wow. And it's, there's a little bit of tingling. You'll know it's working
Starting point is 01:04:03 because the kava from the trocom is, is a little bit numbing. Oh, yeah. And so you get a little bit of a numbing in your mouth while it's happening. And then you feel like you're, just go down. Wow. You know, it's, I love it. Because, you know, I tend to be on the stress side of things more too. And like if you have like a lot of meetings, like a lot of shit, like, you know, you just bring it down, you know. Sounds like an awesome way. I mean, we're always trying to teach people. I think this is actually one of the missing links too for a lot of people with tech today and the amount of stuff, social media, all the things that we're on.
Starting point is 01:04:33 Late at night. Like getting people to have like a bedtime routine. Yeah. It sounds like this would be like an awesome supplement to take post dinner. So much better than alcohol. You know, yeah. Take that. talking about as a replacement for alcohol, right?
Starting point is 01:04:45 Yeah. And I talk about it as the parasympathetic edge, really. And this is something that, Thomas and I were talking about on stage ones, Thomas DeLauer, it's like, if you can give people, especially in the performance world, like, like, let's give you an edge. Yep.
Starting point is 01:04:57 It's called the parasympathetic edge, right? Because if you have this edge, you're going to perform better with your workouts, with your training, with your recovery, everything, right? And then, like, well, what does that mean? Like, well, it's dropping down your nervous system. Well, how do I do that?
Starting point is 01:05:11 Well, let me show you what it feels like. you can give you some calm, let me give you some Z. And then, oh, this is what it feels like. And then, oh, I don't need to train as much because I can recover better, right? I see the benefit. My sleep gets better. And I talk about this a lot with my athletes.
Starting point is 01:05:25 It's like, well, and as soon as you finish your workout, what are you doing? What are you doing? You're going to go run and go to all your meetings. It's going to go bang things out. Or are you going to like give yourself 10 or 15 minutes just to calm, fuck down, right? Because that's going to be a huge difference
Starting point is 01:05:39 on how you're going to recover and see the gains, right? Because you guys know, you don't make your gains in the gym. No, it's after. Well, we say the best athletes, right, have figured that out how to be able to get into that calm, parasympathetic state
Starting point is 01:05:49 the quickest and most effectively. And while they're actually doing the work, right? So I have a friend of mine, he's like the only guy that was a professional running back. He was on the Eagles, and he was also professional. He was an Olympic skier. Only got to do both.
Starting point is 01:06:01 And he told me, like, when he first was doing skiing, he listened to like Metallica and like, you know, hardcore shit. By the end of it, he was listening to Beethoven, Beethoven, right? Beethoven, Chopin, like, things that were relaxing.
Starting point is 01:06:12 Because you don't need, like, we don't need to be more stressed. We need to be, this is not only for working out. This is for, like, if you want to perform better at your job, right? Like, you need to drop down. You can get too amped even for athletic performances. This has happened to me competing in the past where I was so psyched that I would just gas out so much faster than I did in practice. Well, they've done cool studies.
Starting point is 01:06:32 I've shared it on the podcast before that, like, Justin's referring to where they compare like a Steph Curry and with some other random people. And there's a game winner, like, free throw he has to hit. and they measure his heart rate, and his heart rate is, like, resting heart rate for the average person. Like, in the middle of a game where he's been running up and down a court,
Starting point is 01:06:48 it's like, that ability to be able to do that is so unique. Yeah, that's cool. I just call it with my patients, I call it a superpower. Like, and I remind myself this on a regular basis, because if you can just, if you're so sympathetically dominant,
Starting point is 01:07:00 what you don't have a lot of what's called sympathetic reserve, right? So if you're already going in like this, you don't have a lot more you can do, right? But if you're coming down, if you're coming from a very low place, the amount of tension you can put on a muscle, Not of stress you can put on the system.
Starting point is 01:07:14 That's where the change is going to happen. That's where you're going to see the major long-term benefit, right? One of your products has something called corticepon. Is that from corticeps? Yeah. Okay. So what's the benefit of that? Yeah.
Starting point is 01:07:23 So you know the corticeps mushroom, right? I do, yeah. Corticeps has been known for a long time in Chinese medicine is something that helps with energy, helping with detoxification. There's a lot of different compounds in the mushroom. There's one particular compound in there. That is my favorite compound other than methylene blue at this point.
Starting point is 01:07:39 And it's called cortisepin. And cortiseptin is the most active portion of the cortisept's mushroom, but it's only 0.03% of the mushroom by weight, so a very small amount. And what's very, very cool about it is that it's about 100 times more potent as an antioxidant,
Starting point is 01:07:54 anti-inflammatory, antiviral, and it increases deep sleep. And you take it at night, typically. And it has transformed my personal health. I'll say that, because I'm traveling a lot like you guys, right? And whenever you're traveling a lot, you're at high risk of getting sick.
Starting point is 01:08:10 and I just don't anymore, you know, knock on whatever what I have here, but I don't. And my kids, I have a little bowl of it at my house who call it the green stuff, it's green colored. Anytime anybody's feeling like they're getting sick,
Starting point is 01:08:20 they take it. So you can take it prophylactically. We have something called true immune, for example. That's one of our products that I take prophylactically if I'm a place that, you know, I have a higher risk of getting sick at a lower dose. And then if you feel like you're coming down with something, higher dose.
Starting point is 01:08:33 You take it immediately. Like the soon as you start feeling like you get something, like you take your rest of your stack of store. It's not the only thing you take. But you will see a shift in that whole progression. Like my wife, who listens to zero of what I say. She's also a physician. Oh, God.
Starting point is 01:08:50 She's one of those people that gets a cold. You know, she gets the usual cold, but then she gets a cough that doesn't go away for like a month. Yeah. And I can't sleep in the same bed as her. And like, it's the, you know, it's the whole thing. But if I can get her to take the true immune right when she's starting to feel sick, she doesn't get that whole thing. Like, she doesn't get that cough.
Starting point is 01:09:04 And like, it's better for our relationship, right? And better for my sleep scores, too. And so that's such a cool thing about it. And it works like adenosine in the body. So adenosine, yeah, adenosine has a lot of different functions. It's an adenosine, the main people, the way people think about adenosine oftentimes is related to blocking the
Starting point is 01:09:22 indenicine receptor. You guys are drinking something on a regular basis. Coffee. Yeah, caffeine does it. Caffeine does it. Coffee blocks the adenicine receptor in the brain. It makes us feel more wakeful, right? And so what metham, what cortiseptin does is it works just like adenosine.
Starting point is 01:09:35 So it gives you sleep pressure. So it increases your deep sleep, too. So you take it at night. it increases your deep sleep. You will see this if you measure your scores as well. And at the same time is giving you antiviral, anti-inflammatory and anti-alactantia. Can you take it at the same time as the Z and the calm moment?
Starting point is 01:09:48 Yeah, I want give me, okay. So this is like the last three months. I'm on this like mission to, I'm oaring, tracking. Yeah. And like trying to, I'm shooting for, I haven't seen a 90 score ever. I got one today.
Starting point is 01:10:01 Okay. Okay. So give me. See level. Give me the, the whole stack of what I should take in a day to try and optimize. I want to know, methlin blue. I mean, it's so variable, right?
Starting point is 01:10:12 Because everybody's gonna be different, but what I would say is that you need to have a good enough support from mitochondrial support during the day. You have to make sure that you're having times when you're parasympathetic during the day too. So you're going, so the most beautiful nervous system is one that dynamically oscillates between
Starting point is 01:10:28 sympathetic and parasympathetic throughout the day, but the majority of your time is in parasympathetic. Okay. The majority of your time should be in chill mode. Right. This is why you see older, you know, tribal cultures that hang around most of the day doing nothing, right? And then we're just relaxing.
Starting point is 01:10:45 And then they, you know, then they're hunting. Like, then they're fishing. Like, then they're having sex or whatever it is. Like, but they're doing things periodically and sympathetic. So the best way to get the best sleep is have the most regulated nervous system and have the most mitochondrial support. But then you're thinking about, okay,
Starting point is 01:10:59 three hours before bed, I'm not going to have any more food. Typically, you don't want to have a lot of food before you go to bed. Good three, two, one rule. Right. You got that, right? And then you want to be winding down your nervous system
Starting point is 01:11:09 within those three hours, right? And so how are you getting more parasympathetic? What are you doing? No TV, no TV, no phone, yeah. Or if you're doing it, I mean, most people are going to do some of that. At least you're wearing protection, right? Condoms for your face. Blue blockers.
Starting point is 01:11:22 We should call them, right? Condoms for your face. I thought about that. That's good. I should tell my friends that have those companies. It's called them condoms. Anyway, so yes, you're protecting your face. You know, there's also the idea that you have photoreceptors in your skin,
Starting point is 01:11:37 So in general, it's about trying to keep the lights dimmer And then trying not to be too activated before bed You don't want to do too much heavy exercise before bed if you can Like I'm not a big fan of people doing like cold plunges and shit before bed If people do this like they go back and forth from hot to cold at night I don't think it's great for most people I think if you're pretty well optimized you can do it But if you're not it's probably going to be too stressful
Starting point is 01:11:59 To release all those neurotransmitters And then you're thinking okay now 30 minutes before bed what am I doing So I you guys remember Pavlov and the dog and things, I talk to my patients about salivating for sleep, right? Which is like you do the same thing every single day, no matter where you are, no matter what time zone for at least five to ten minutes before you go to bed every single time. And try to go to bed at the same time. Yeah.
Starting point is 01:12:22 Every single time. And then if you're stacking in the products, which I do, I'm thinking about our trozy, a half of that and a half of our tromune combined together. Okay. Because that's typically about a 30 minutes to an hour before you go to bed. Yeah. You can use them as a trokey. You can put them up in the mouth and let them dissolve,
Starting point is 01:12:39 or you can swallow them, you know. Obviously, it's an empty stomach, so it's pretty well absorbed both ways. Yeah, yeah. And then, you know, you go to bed and you go to bed the same way every night. Yeah. The same sleeping position, the same cover,
Starting point is 01:12:51 the same sound machine, the same eye mask. Like, it sounds like a lot. But in the end, it's not. No, no, no. And I appreciate you framing it this way because this is what we talk about on the show all the time. And this is even what I've communicated.
Starting point is 01:13:02 I was just yesterday we were talking about this. And there is nothing that had so far that I've been. able to do supplement-wise or anything else than the things that you listed first. Like that is getting my good exercise in, making sure that I calm down for, shutting all the stuff down, being consistent. I can go four days in a row of that, like you just said, perfect consistency. And I'm scoring in the 80s.
Starting point is 01:13:22 As soon as I stay up an extra two hours later, just like that, it doesn't even matter if I had the supplement stack. That disrupts the most. So I'm doing those things. Yeah. Now I want to know what the... Yeah. I mean, one of the things that we also like to do, and this is helpful, maybe not for you,
Starting point is 01:13:35 but for those that are listening is that Dr. Ted is, you know, again, the guy that I get a lot of my sayings from these days, likes to say that your day starts when you go to sleep, not when you wake up. So make it the priority. Instead of it being the last thing you do every single day, make it the first thing you do. Isn't it ironic that we talk about this too all the time on the show is that we've put so, there's so many books about morning routines and stuff like that. And yet I would argue that your night routine is far more important, way more important
Starting point is 01:14:04 than your morning. But we just don't talk about that. Don't talk about it. Because sleep is, it's the afterthought, right? And then this is, it's been a big deal for me. I mean, I was in the hospital working for years and getting called at home and like, I just wasn't getting, you can, the thing about is, if you're relatively healthy, you can tolerate this for a while until you can't.
Starting point is 01:14:21 Right. And then you start falling off that cliff. Like, why can't I recover as well? Why is my mood all over the place? Why am I tired, but wired all the time? Like, well, because your nervous system is shot and your mitochondria need more support. And you can't just think you're going to take a supplement and that's going to be the end all be, right? That could help you, and it could be a good start, or it could be something that,
Starting point is 01:14:39 you know, in addition, you add to the other stuff. Most people are going to go the other way around, which is like, they're going to want a pill first, right? They're going to want to supplement. And that's what I tell my patients all the time is like, look, I hope over time you don't need as much of this, but like let's get your nervous system working well or better. Like, let's get your mitochondria more supported. And then over time, as you're getting your diet better optimise, lifestyle better optimized, getting out of a shitty relationship, like, you know, getting a sleep divorce, you know, you guys know, you guys know, half of U.S. couples, I think, live in different, sleep in different rooms now.
Starting point is 01:15:07 Is it half? About half? Are you serious? Wow. It's like back in the 40s. They have like one bed for sex or they change beds. I don't know it all good. But there's also just another hack for people is just getting a separate set of covers.
Starting point is 01:15:20 We have sleep eight. So my wife, which blows my mind is at 90 degrees. I'm over here at 55. That's crazy. Yeah, yeah, yeah. So you have different covers, different mattresses. You're not like, you know, trying to steal the covers from your spouse or partner. That's another way to do it.
Starting point is 01:15:33 Yeah. But like they've actually done studies. is like if your partner is snoring next to you, your cortisol rises every time they snore. Even if you think you're sleeping all night. Well. Yeah, so you're not getting good rest. And so you have to start off with the basics.
Starting point is 01:15:45 And so when I work with patients, it's like, what are the basics for them? It's either sleep, stress, mitochondrial function. That's all happening at the same time. The question is where you start. But almost always, if sleep is the issue, you start with sleep. Because if you can get them to sleep better,
Starting point is 01:15:58 everything else is going to get better. This is why I love these tools that we have now like ORRing is because I think for years, as a trainer over 25 years now for us, you were playing that guessing game so much. And I'm sure there's a major individual variance of what each person fills like with a score of an 80 or whatever,
Starting point is 01:16:15 but at least gives you a metric that you can go. And it's very clear to me. There is a clear difference between, you know, two, three days in a row of 80 scores versus a 67. And it is you can feel. You can. And so I can see that now. And then I can see as I apply these habits and routines like,
Starting point is 01:16:34 what a difference that makes. Yeah. Turozi has been great because it has eight different ingredients in there. And the problem with most sleep aids out there is that they're just going to trash your architecture. You know, so your sleep architecture is the idea that you have to go through various cycles while you're sleeping.
Starting point is 01:16:46 You have four stages of deep sleep. You have REM sleep. You're supposed to do this every 90 minutes. And then in the beginning of your night, you have more deep sleep. In the end of night, you have more REM sleep. This is typically how you guys, if you're looking at your ring, you'll see this. But if you take something like THC, if you're taking like TACS is your deep sleep. Yeah.
Starting point is 01:17:00 Alcohol trashes all of your sleep. Right? And then, you know, Benadryl or other, even, melatonin, they're going to give you, Benadryl's going to do nothing good for you, but melatonin will give you like a little bit of help. It's not going to do the whole thing. So people tell me, like melatonin doesn't work for me. I'm like, yeah, because you were just taking melatonin. You know, that's one of like six different sleep signals. Like, what about GABA? What about adenosine? Like, what about serotonin or melatonin together? Like, you combine these things
Starting point is 01:17:22 together. Yeah. That's why Trosey is so powerful. Because it has that comprehensive support. Yeah. And I always tell my patient's like, look, I want you to, if you're not sleeping, that's the first thing we've got to figure out. Because if that doesn't get better, nothing's going to get better. And this is something I've learned over the years, right? Like, you can get people expensive therapies and, like, go in a hyperbaric chamber.
Starting point is 01:17:41 But if they have sleep apnea, like, doesn't fucking matter. Oh, yeah. Or if, like, if they have terrible stress, it doesn't matter, right? And so, like, don't waste your money. And, like, I tell, and that's why I get disinvited. Like, don't waste your money on this great technology if you're just going to be doing the same thing that got you where you are.
Starting point is 01:17:58 Well, Scott, I appreciate what you guys do because I'm pretty hyper-aware of how sharp I can be because of what we do. So, you know, if I didn't, you know, have conversations with people or do a show with my partners every single day, I mean, it wouldn't make that big of a difference. But I need to be sharp. And so the methyl in blue product you guys make, that's like one of my favorite things. And it definitely improves my ability to just do this. I can't wait to mess with the sleep stack because I'm, like, so into this right now.
Starting point is 01:18:24 I've been tracking. So it'll be a fun thing to... Let's tell me how it goes. Yeah, yeah, I totally well. I've never scored in a 90s. So it's... Yeah. Well, I only get 90s.
Starting point is 01:18:30 when I come back down to sea level. You know, I got to be saying, when I'm in Colorado and I come down and I sleep in a hotel room, even if I sell it sounds like shit, I still get a 90 because my HRV goes up because I have more oxygen around. So that's how it typically goes.
Starting point is 01:18:42 But yeah, I mean, I love our products because they really do serve a purpose, which is they help you now while you're on your path. And hopefully over the long term, you need them less because you're more optimized and doing the things, but we're all getting older too. And we all have more stress on us at times, you know, sleep stress
Starting point is 01:18:58 because you have a bad night of sleep, right? you know, or you're on a travel, you're going traveling or whatever it might be. Yeah. And so what I love about our company is that I'm a physician. Like I do this shit for a living. Like I'm working with patients. I work with lots of my colleagues that do this all the time.
Starting point is 01:19:12 I see what's working. And, you know, my colleague, Dr. Ted and I, we've seen what's working for over 20 years. And we know that one sleep stack is not going to work for somebody else and somebody else. And then we have these trokeys that you can titrate. You can take a quarter. You take a half. You're not like relegated to a capsule and have to figure out how to take out like half,
Starting point is 01:19:30 to the stuff and figure out if it works for you. And so trogis are great. They're fast. They're bioavailable. And we have a whole nonprofit organization that trains practitioners on a different way of doing all this. So you don't have to be in, if you're a physician and you're listening in your conventional doc and you want different training, like we have that for you.
Starting point is 01:19:46 And that's why I feel comfortable talking about the products. It's like because we have a whole ecosystem for people to educate them. And then I say this with absolute truth. Like if you don't need my supplements, our products going forward, great. That means you've been well optimal. and you don't need them as much, awesome. Well said, Scott.
Starting point is 01:20:03 Thank you so much for coming on the show. This has been awesome, man. Appreciate you. Thank you, guys. It's been fun. Thank you for listening to Mind Pump. If your goal is to build and shape your body, dramatically improve your health and energy,
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