Realfoodology - BRCA, Modernizing Cancer Treatment, + Medical Ketosis | Dr. Thomas Seyfried
Episode Date: September 3, 2024EP. 211: Welcome back to the Realfoodology Podcast! In today’s episode, I’m thrilled to be joined by Dr. Thomas Seyfried, a leading professor at Boston College. We explore his groundbreaking resea...rch that redefines cancer as a metabolic disease, challenging the traditional genetic view. Discover how this new perspective could revolutionize cancer treatment and empower us with actionable, less invasive strategies. Don’t miss this enlightening discussion that might just change the way you think about cancer care. Timestamps: 06:35 - Rising rates of cancer in youth 12:12 - Metabolic therapy 15:33 - Glucose and glutamine 19:04 - Keto, Carnivore, and nutritional ketosis 23:40 - Ancestral diet and lifestyle 27:17 - Artificial sweeteners 32:50 - Ketosis and glutamine blockers 36:13 - Global metabolic health 39:46 - Lack of knowledge and lack of accessibility 47:12 - Current cancer treatments 53:41 - Epigenetics vs diet and lifestyle  58:36 - Cancer treatment history and breakthroughs 01:00:30 - Supplements 01:02:42 - Finding a balanced diet 01:05:57 - Staying at a healthy weight 01:09:15 - Mitochondrial health 01:15:52 - Genetics and cancer 01:20:06 - Current cancer treatments 01:30:15 - Dr. Thomas’s health non negotiables Sponsored By: Puori Go to Puori.com/realfoodology and use code realfoodology to get 20% off Kion Use my link to save 20% at GETKION.COM/REALFOODOLOGY Seed Go to https://seed.com/realfoodology and save 25% your first month with code REALFOODOLOGY Organifi Go to www.organifi.com/realfoodology and use code REALFOODOLOGY for 20% Off BIOptimizers MagBreakthrough Get your free bottle of magnesium breakthrough while supplies last at magbreakthrough.com/realfoodologyfree ARMRA Collostrum Get 15% off your first order at tryarmra.com/realfoodology Check Out Dr. Thomas: Instagram More Dr. Thomas Check Out Courtney: LEAVE US A VOICE MESSAGE Check Out My new FREE Grocery Guide! @realfoodology @realfoodologypodcast www.realfoodology.com My Immune Supplement by 2x4 Air Dr Air Purifier AquaTru Water Filter EWG Tap Water Database  Produced By: Drake Peterson
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On today's episode of The Real Foodology Podcast.
They have a family of chimpanzees living with people down in Florida there.
They got the whole, the two families are together.
It's like nuts.
Anyway, they eat together at the same table.
They say for dessert, we're going to have jelly sandwiches.
Well, these damn chimpanzees are banging on the table.
They're going nuts for the jelly sandwiches.
You give them chalupas and Big Macs every day.
Oh man, they're going to have the same problems we have.
Hello friends, welcome back to another episode of the Real Foodology Podcast.
Today is a really exciting episode and I am so excited to dive into this one.
I sat down with Dr. Thomas Seyfried.
He is a professor of biology, genetics, and biochemistry at Boston College.
And his research
focuses mainly on the mechanisms of chronic diseases like cancer, which is a lot of what
our episode is about, but also on epilepsy, neurodegenerative lipid storage diseases,
and caloric restriction diets. He has been published in over 150 peer-reviewed publications, and we talk about his findings
that he has found regarding cancer.
What he has found in his studies
will change the way that we treat cancer in the future.
He talks about how cancer is not a genetic disease.
Genetics play a small, small role sometimes,
but what he found in his studies is that it is actually a metabolic
disease. And we go into depth about what that really means and what that looks like as far as
treating cancer. I know cancer can be a really scary conversation to have. And it is concerning
as we look around. I think everybody at this point knows at least somebody that has been
diagnosed with cancer. And there's been a lot of talk about how cancer has been on the rise,
especially in younger and younger people, which is really concerning. But this conversation
just gave me so much hope because what he has found means that we are very much in control of
this. Now, I don't want to say that we are entirely in control
because obviously there's always other factors at play, right? And we will never be fully in
control of anything in our lives. But what's cool about it is that the mainstream narrative is that,
oh, it's just genetics. This just happened to you. It's bad luck. There's nothing you can do about
it. You just have to take really extreme interventions. And what he's finding is that this is not the case.
In fact, there are interventions that we can do
that are not as invasive,
that aren't so hard on the body,
that don't leave you with a destroyed immune system
and feeling like crap all the time.
And there's a lot that we can do.
And it leaves us feeling incredibly empowered
knowing that we do have a lot of control in this situation.
So with that, I really want to get into the episode. It's so juicy. I think you're going
to love him. He's also just a really lovable guy. We had a great conversation and I really enjoyed
it. So I hope you guys love the episode. Please, if you could take a moment to rate and review.
Also, if you want to tag me on Instagram, post about this,
and please share it with everyone,
share it with your loved ones,
share it with your doctors,
because our doctors need to be knowing
about this data and this information.
And if you do post this on Instagram,
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and if you also want to tag and follow
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we just started a new Instagram for the podcast,
and we're posting a lot of clips on there that you're not going to find anywhere else. So just want to take a moment to
say, I really appreciate you listening. I'm so grateful for your support. Without you listening,
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on the podcast today. Right before we started recording, you said something to me and I want
to start on that. And you said that you were seeing more young patients with cancer and it's really concerning
you.
Why do you think that we're seeing such a rise in cancer right now?
Well, most of it has to do with diet and lifestyle.
It's not a genetic disorder.
So it has to be group in Korea, oncologists and nutritionists and these kind.
And he wrote, he said, here is what you need to do to get cancer.
All right.
I have it on my board here.
No exercise.
No happiness or friends, uh,
poor food, poorly nutritious, high, highly processed foods. A lot of it, uh, a lot of emotional stress and, and bad sleep. Uh, you put all that together for several decades
and you put yourself at risk for cancer.
So it's never one thing.
It's always a conglomeration of things.
I have no clue as to what's happening
for why we have so many people in younger age groups who are
emailing me for help. But I see it seems like in the mid-30s and 40s, mid-30s, early 40s,
I'm getting a lot more of these. I used to be, you know, 60s, 70s, 80s. There's still a lot of those for sure.
But what the hell is going on with these young people? And, you know, a lot of it had to do with
obesity epidemic and type 2 diabetes, which is much more common in the younger people today
than it was in the past. But there's other things that must be involved as well. We know one thing. All cancers arise from chronic damage to the mitochondria of the cell.
This is the organelle inside cells that generates the energy.
And when that organelle gets corrupted chronically, it leads to a shift in energy from oxygen, using oxygen to drive ATP energy to fermentation energy without oxygen.
And a lot of these chronic stresses and bad food and emotional stress can damage mitochondria
chronically, leading to what we call dysregulated cell growth which
is cancer cancer is dysregulated cell growth and you have to say what causes
it what causes cancer is chronic damage to the respiratory capacity of the cell
well how does that happen well it can happen from viruses oncogenic papilloma
virus hepatitis C virus it can can happen from smoking. It can happen from chronic stress. It can happen from chronic inflammation. It can happen intermittent, like in breast cancer,
for example, and milk duct gets occluded, leading to an inflammatory microenvironment,
leading to damage to mitochondria over time, leading to dysregulated cell growth. So we've put all the
parts of the puzzle together. You know, carcinogens, people cause carcinogens. What is a
carcinogen? It's a chemical that's been recognized to cause cancer in a mouse or a rat, and also in
humans. Like, for example, the talcum powder fiasco.
Yes, the Johnson & Johnson.
Johnson & Johnson.
Okay, I was contacted many years ago by someone from that.
And they said to me, talcum powder cannot cause cancer because it doesn't cause mutations.
And I said, mutations have nothing to do with cancer.
Talcum powder can go up into the urogenital tract, lodged in an ovary or some part of a female
anatomy, leading to an inflammatory foci in some part of the tissue, which then damages mitochondria,
causing a shift from oxidative phosphorylation to fermentation
and dysregulated cell growth just like asbestos asbestos that everybody fears about for lung cancer
doesn't cause mutations in mutation screening systems but everybody knows asbestos can cause
lung cancer because it lodges in the lung tissue leading to inflammation damages to mitochondria
energy metabolism shifts and you get dysregulated cell growth.
So we know how all cancers start, from damaged mitochondria with a compensatory fermentation.
Now, when I say that, there are some cells in our body that rarely, if ever, get cancer because they can't replace oxygen energy with fermentation energy. And this is cardiomyocytes. Rarely do
you ever get a tumor in your heart, heart muscle, and also neurons of the brain. You get a lot of
brain cancer from glial cells, but not from neurons. They can't shift from oxidative phosphorylation
to substrate. So we know why cells get cancer and why cells don't. And we know pretty much
exactly how it all happens.
So can we explain that to people?
Because you've talked about fermentation a couple of times
and you just said that the brain cells and our heart cells,
certain brain cells can't get it
because they can't replace oxygen with fermentation.
So what does that mean exactly?
Well, that means that, okay, so you're breathing.
I'm talking, you're breathing.
All the cells in your body, your brain, your muscles, your okay, so you're breathing. I'm talking, you're breathing. All the
cells in your body, your brain, your muscles, your heart, they're all getting energy. Okay. Now,
God forbid, if you want to stop all that real quick, you take cyanide. It's like, say,
they drink the Kool-Aid. Why do they drink? Kool-Aid was laced with cyanide. Everybody's
died real quick. Yeah. It shut down the mitochondria immediately, right?
And you're dead, right?
Quick, within a minute or something.
Okay, cancer cells, cyanide doesn't kill cancer cells.
Why?
They don't use oxygen for energy.
They're mostly fermented.
They use an ancient pathway of fermentation.
Where did that come from?
Don't forget, our Earth is like four and a half billion
years old for a large part of the earth's the earth's existence there was no oxygen in the
atmosphere but there were living cells and those cells grew unbridled on dysregulated cell growth
and they used energy called fermentation as energy without oxygen there was no oxygen in the
atmosphere yet we had cells that were growing.
Well, how did they grow? They used these ancient pathways of fermentation. All of our cells in our
body today have those heirloom pathways, the glycolytic pathway. They're very minor because
most of our energy is coming from breathing oxygen. But when you have cancer, those cells
explode back and they use these ancient pathways and they build them back right back up again. And what fuels these pathways? Two fuels only that we can find,
the sugar glucose and the amino acid glutamine. And glutamine is an amino acid in our body,
and it's the most abundant amino acid. It's in our bloodstream, and it's there for our gut health. It's there for our immune system, for the urea cycle.
It's a very important amino acid.
But the cancer cells suck that down as well.
So you have to know, to kill cancer cells, you have to take away the two fuels that are
driving the fermentation metabolism, and that's glucose and the other is the glutamine.
Now, to reduce reduce glucose you stop eating
Water only fasting zero carb diets this kind of thing. It's easy to stop glucose
It's hard because your brains are addicted to take time. Yeah, so it's hard, but it doesn't mean it can't happen
Targeting glutamine is a little bit more challenging. We have drugs that will do that. They have to be used strategically. Doses, timing, and scheduling have to be monitored very, very carefully. But if you hold the choke
hold on the glucose, keep it down, and then you go after the glutamine with drugs, exercise,
and this kind of thing, you can manage that as well. We published all of this. It's called the
Press Pulse Therapeutic Strategy for Managing Cancer. You press glucose, you pulse glutamine,
and you do different kinds of things to bring the body into a state of health while slowly
degrading the tumors. And this is the strategy that will eventually become the standard of care.
When you're my age and you're looking around, they're going to be doing metabolic therapy.
Everybody who has cancer is going to do metabolic therapy because by that time, they'll know that
it's a metabolic disorder and they will have figured
out and perfected dosage timing and scheduling for simultaneously targeting glucose and glutamine.
So my question is, and I already know the answer, I think, but I want the audience to
really understand this.
Because from my understanding, there's not a diet that can reduce glutamine.
We can obviously reduce glucose in our diet, but we can't reduce glutamine, right? But is there anything in our diet that can reduce glutamine. We can obviously reduce glucose in our diet, but we can't reduce glutamine, right?
But is there anything in our diet
that would increase glutamine?
And I have another question.
We know that glutamine is an amino acid.
So is there a component there with eating protein
that would cause glutamine to increase in the body?
Glutamine is already at a maximum level in our body.
If you look at, compare glutamine with all other amino acids,
it's already massively greater
than most amino acids in the body,
most other amino acids in the bloodstream.
So it's not clear whether, like a carnivore diet,
the power of the carnivore diet is not the fact
that it might elevate glutamine.
Glutamine is already maximally elevated.
It's good because it lowers blood sugar.
So you're not eating carbohydrate if you're eating meat.
Now, there might be some glutamine in the meat, but you're already maxed out in glutamine.
So exercise will lower glutamine.
And that's been shown by the group, my late friend George Cahill, who was the president of the Joslin Diabetes Center.
He published a paper showing you could lower gluten.
But it's not lowering enough to kill the tumor cell.
That's why we use specific drugs, glutamine targeting drugs.
And that goes after the tumor.
So that specifically goes after the tumor. But you also have to be careful in using that because when you kill cancer cells in your body, you can't let the dead corpses, the bodies of the dead cells,
hang around. So our immune system comes in as the undertakers and they pull away and they digest the
dead cancer cells. But they also need the same fuel that the tumor cell needs. So they use the
glutamine to pick up the dead cells. The
cancer cells use the glutamine to try to stay alive. But when you target glutamine, you kill
the cancer cells. You simply paralyze the immune system. You don't kill it. You just paralyze it
because cancer cells are very, very weak cells already. They're not strong. They're already on
the precipice of death because they need these two
fuels. And when you start lowering blood sugar, they get marginalized. And then you come in with
a low dose of glutamine targeting drugs and you start picking them off. And then you allow the
immune system to pick up the corpses. And then you go back and kill camp, let the immune system
come in. It's back and forth, back and forth while you're choking the glucose down, putting
them at a tremendous competitive disadvantage. The body, because it has a massive healing capacity,
the body is a healing machine. If you give it the opportunity to heal, it will heal.
And if you put the body into these metabolic states that we're talking about, the body,
the normal cells of the body go after the tumor cells and dissolve them and eat them themselves because we're stressing energy. So every cell in our body must recognize its existence. It must justify its existence.
Therefore, you have to have maximal energy efficiency. Cancer cells don't do that.
So the body turns on the tumor and eats it. It's called autolytic cannibalism.
But you don't get into those stages unless you understand the whole metabolic process here. Unfortunately, that's not known to the majority of people,
oncologists or medicine physicians. Yeah. I mean, that's why I wanted to bring you on the podcast
because what you're talking about is not very widely known. I mean, we hear little whispers
of it, right? Like I hear a lot of conversation about going on a keto diet, for example, and
that's what I was just going to ask you. Do you think that going on a keto diet or carnivore diet is beneficial in conjunction with
taking these glutamine blockers? Well, when we say keto diet, what we call is nutritional ketosis,
therapeutic ketosis. And what is that? We published the paper, the Glucose Ketone Index Calculator,
where you can use the K the the keto mojo glucose
ketone monitor and we're learning now we're getting these free Libra's we're
getting the technology for measuring blood sugar and ketone bodies is
improving you a person would measure their GKI glucose ketone index and as
you go on water fasting carnivoreore diets, ketogenic, whatever you wanna do, they go down.
The GKI starts to go down.
And then once you get into these zones,
that's when the glutamine targeting drugs
have their maximal benefit.
But each patient is a separate entity.
So, you know, like how do I get into a low GKI?
Well, don't eat any carbohydrates for 10 to 14 days and see how that
works. And you'll start to see the GKI going down, down, down. And then people, some people say,
well, I can't get it down. Then don't eat anything. Just do water. Well, I'm not going to do. Well,
then don't, don't, don't come to, don't bother me. You want to get yourself healed? Okay, so go to somebody else.
The issue here is, so what does it mean to be in ketosis?
You know what it means?
It means going back to our Paleolithic existence on the planet.
Don't forget, we're a species that existed about 1.5 million years.
And we were almost always in ketosis during our Paleolithic period of existence.
We were hunter-gatherers for hundreds of thousands of years, right? What does that mean?
You're a tremendous amount of exercise. You're not eating highly processed carbs. You're trying
to kill a woolly mammoth or some deer or some buffalo or whatever the hell you're going to try
to kill. A lot of energy goes into killing a buffalo.
You know how hard it is to skin this thing and chop out the meat and chew all this stuff?
Nobody's standing with a jelly donut where they're hacking out the buffalo's liver, right?
Exactly.
Right, right.
They might be munching on some berries, but that's about all.
Yeah, only during the season.
Exactly.
You're not going to be, that's why you have fests around certain seasons,
because it was, whoa, we have a few ripe piece of fruit, and we get all excited.
But it's all natural. There was no highly processed carbs. What was the stress? The
stress was trying to find food to eat, all right? So this was our
existence for hundreds of thousands. Everybody was in ketosis at that time. What killed us back then
was largely infections and injuries, all right? We were not dying from cancer, a coronary vascular disease, type 2 diabetes, macular...
We didn't have dementia.
Cancer wasn't...
How do we know that?
Because when you look at aboriginal tribes,
like some physicians have done looking at these tribes,
they were not...
Cancer was rare.
They didn't even know what it was.
Some of them didn't even have a name for it.
It was so rare.
Inuits and Eskimos and African tribes, rainforest people,
aboriginals from Western, these guys didn't have cancer.
It's only when the great American diet lifestyle
come into your existence,
then you get all the chronic diseases.
And that's because our technology has moved so fast,
much faster than our biology.
So we, our technology evolved fast.
Everything is convenience.
Got to have convenience.
Run out.
We don't even have to unass the car.
We just run in and get the donut or the hamburger passed right through the window.
Don't even have to get out of the car.
No effort.
It's really sad.
Think about trying to track down a woolly mammoth, the amount of effort that would go into that.
And then hacking them apart and trying to eat it. I mean, you're exhausted eating the damn thing.
Here, we don't have to do anything. And then everybody wonders why we're so fat.
You know, the issue here is the obesity epidemic today is evolution in action. We existed on the
planet for hundreds of thousands of years, never having carbohydrates in the diet, exercising all the
time. And then we've geared ourselves to store carbohydrates and now it's available everywhere.
And not only that, I think this is a really important piece or point to make in this is that
there was no confusion about what to eat. Our ancestors were not confused on what to eat and
what was real food. And I have never seen more people more confused about what to
eat now. And I don't say that to shame them. I just say that like, our ancestors knew exactly
what to eat. And now we're so confused and everybody's fighting online over eggs and meat
and everything else. And yeah, we're not in a great place right now with our food landscape.
No, no. In fact, there was no confusion about what to eat. Anything that will walk, crawl,
swim, or fly would be consumed.
Or grown, but yeah.
Well, you didn't grow.
Well, depending on where you were.
We started growing stuff in the Neolithic period.
That's when civilization started because we didn't have to go and gather food because we could start growing it.
We would domesticate the meat, the sheeps and the cow
and this kind of thing. And you build civilizations because you didn't have to be hunting for food.
Food was there. So we could build societies around the food source. Everything is food.
Everybody, let's be honest, everybody's looking for the next big meal, right?
If you don't have to bust your ass looking for the meal, it's right there.
Hey, that's very convenient. But now the convenience has come to the point where we're putting ourselves at tremendous
health risks for all these chronic different diseases, cancer being one of them.
So we learn this if we understand evolutionary biology.
And one of the great lacks of knowledge is people just have no clue about evolutionary
biology.
Where did I come from? How
did I get here? What's the history of the earth? What's the history of our species? What's the
history of all? We have chimpanzees and gorillas. They're 98% similar to us in gene and protein
sequence, and they've never documented a case of breast cancer in a female chimpanzee.
Wow, to this day? Yeah, never.
Wow.
They don't get breast cancer.
Why?
Because they're living either in the jungle or in the zoo
according to their diet and lifestyle.
And I keep telling people on these podcasts,
I went to the zoo in San Diego and I said to the,
they have some bonobos there,
these half chimpanzees, small chimpanzees,
and they got gorillas down here
at the Franklin Park Zoo here in Boston. And I said, how come you don't give these guys pizza and jelly
donuts and all this kind of stuff? He said, oh, that would be animal cruelty, very unhealthy for
them. I love that. It's true. But then we see people eating donuts every day. Oh, yeah. And
don't tell me those chimps would not eat those donuts. They have a family of chimpanzees living with people down in Florida there. They got the whole,
the two families are together. It's like nuts. Anyway, they eat together at the same table.
They say for dessert, we're going to have a jelly sandwiches. Well, these damn chimpanzees
are banging on the table and going nuts for the jelly sandwiches. That really is funny. Yeah. So, I mean, you give
them chalupas and Big Macs every day. Oh, man, they're going to have the same problems we have.
Exactly. Diabetes, cardiovascular disease, cancer. Yeah. You name it. And then everybody's
scratching their heads going, hmm, why are all of these skyrocketing? Exactly. And obesity. You
get the whole range. You get the whole range. But guess what?
They will not allow those kinds of studies to be done because it's animal cruelty.
You can't do those studies.
We only do them on ourselves and wonder what's going on.
I mean, we are the experiment right now.
It's really what's happening.
Yeah.
So we can't believe what's happening to us until we do it on a chimpanzee or gorilla,
but we can't do that because it's animal cruelty.
I mean, it really is backwards.
We're living in a backwards time.
So I'm really curious because I've never heard somebody
in your camp who's talked about this.
What are your thoughts on, so we know sugar,
obviously glucose is running that pathway.
Is there any, any artificial sweeteners
or sweeteners like monk fruit, stevia, erythritol,
are they also running on that fermented pathway?
You know, I don't know.
People put it in the stuff.
It's like you said,
there's so many things
that we are putting into ourselves
that may or may not be natural.
Yeah, and it's hard to do those
kinds of, who wants to do this? You know, we're in the business of managing cancer once you get it.
Yeah. You know, it's not like, I know the guy says, oh, I should have, I know I should have
done this. I shouldn't have been smoking. I should have done more exercise. I should have blah, blah,
blah, blah. Okay. Now I have pancreatic cancer, glioblastoma. Now I have
bladder cancer, breast cancer, colon cancer, you name it. Now what are you going to do?
All right. So now we know that these tumor cells can't survive without the sugar, glucose,
and the amino acid glutamine, nor can they burn fatty acids or ketone bodies. And we've published
all these papers. So we know now how to to manage cancer you have to shut down the two fuels driving the fermentation and then you have to
give the body the normal cells that can burn normally which is ketones and fatty
acids which the cancer cell can't use so the rest of the body gets healthier and
healthier while the tumor cells get weaker and weaker and die and this is
the strat not that complicated and it's based on hard science that we have published
and others have published over and over again.
It's just that it's not being used in the top oncology centers.
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This is really exciting. Organifi now has kid stuff. They just released
two kid products. One is called Easy Greens, and it's a refreshing green apple juice where kids
will never know that it's packed with veggies. And the other one is called Protect. It's a
delicious wild berry punch like the Kool-Aid that we used to have as a kid, but without any sugar.
This is really exciting. And if you've listened to the podcast for a while, you know that I'm a
huge fan of Organifi, and most specifically because every single product that they make is glyphosate
residue free. So you know that you're going to be able to give these powders to your kids and
know that they will be able to consume them safely without any glyphosate in it. So let's break down
each one. The Easy Greens is a nourishing and delicious blend of superfoods and veggies that
provides essential nutrients, probiotics, and digestive enzymes to bring balance to kids' growing bodies without fillers, additives, or
junk. It helps to fill in nutritional gaps, aids in growth and development, supports digestive health,
has a rich micronutrient profile, and includes digestive enzymes. This would be a great way to
sneak in greens for your little one without them actually knowing that it's healthy for them.
And the second one, which is the wild berry punch similar to Kool-Aid is called Protect. And it is to support your child's
daily immune health with food derived nutrients that work to strengthen their body's first line
of defense. I know just through girlfriends of mine that have children that when your kids are
going to school, going to daycare, they're coming home sick a lot more often just because they're
getting exposed to different kids and different viruses when they're out in the world playing with kids. So this would be a great
way to help to support your little one's immune health. It's organic and it's also made with real
whole food ingredients. It has a delicious berry taste and it's low sugar and it's gentle enough
for kids to take every single day. And I really love the ingredients in this one. It's orange and
acerol cherry, which is a powerful source of vitamin C and antioxidants.
Astragalus, elderberry, and propolis.
These are all really great for overall immune health.
If you want to try the products that I talked about today
or any of the Organifi products,
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Again, that's Organifi.
It's O-R-G-A-N-I-F-I.com slash realfoodology.
Can I ask you more specifically really what that looks like? So does that mean that somebody is
in ketosis and then they're taking a glutamine blocker, but how long are they taking that
glutamine blocker? Because you're saying you go on and off of it. Is this like you take it one day,
you don't take it the next day,
or is it like you take it for a week?
Yeah, that's what we are now,
dosage, timing, and scheduling.
So usually a person will come in to a clinic,
a clinic that understands what we're talking about,
and a massively thorough blood work
is done on this individual.
Everything, everything you can do,
looking at blood, scanning the person, non-invasive, no biopsies, none of this stuff. You look and you
can determine overall what's the level of health status of the individual already.
Not everyone, many people though are out of whack with respect to their blood markers,
their lipid panels, their micro and macronutrients, vitamins panels, parasites, and all kinds of
stuff. So you have to bring that individual back to a semi-state of health, monitoring the glucose
ketone index, checking the PET scans, MRIs, CAT scans, these kinds of non-invasive ways to determine
what the nature of this problem is. We don't like to use biopsy for fear of spreading the tumor around.
As a matter of fact, we have dozens and dozens of articles for almost every major cancer
that has linked a certain biopsy.
Not that it doesn't happen to everybody, but it certainly happens enough.
Even if it happens to one person, it's too many.
I agree.
So the issue is, okay, we have this person now move to a state of health.
We got a low GKI. That means there's tremendous pressure on the glucose availability to that
tumor. Then we start monitoring the tumor and say, how's it changing? I've never seen it get
bigger. I've seen it stabilize and sometimes shrink, sometimes go away completely.
But most of the time, it just stops, doesn't get bigger.
Sometimes it gets smaller.
And the circumference around whatever you're looking at seems to get sharper.
Then we come in with dosage timing and scheduling on the glutamine targeting.
And then you monitor more.
Make sure the blood work
always stays straight. So this is mostly the patient. And I'm saying like, how often do you
do the blood work? Well, you can do it every month or whatever. And then you do MRIs, CAT scans,
or things like this. And then the patient and the attending physician, healthcare provider,
go together looking at how things are changing. And the other question you ask, how are you
feeling? How do you feel? That's a very important question. Because if you're on chemo and radiation,
how do you feel? Oh no, man, I feel horrible. Diarrhea, fatigue, nausea, vomiting, I don't
feel good. Well, we don't ever want that. When you're
doing metabolic therapy, only at the beginning, when you're trying to get rid of your addiction
to glucose, do you get a little malaise? It's like trying to get rid of nicotine or alcohol
or any kind of an addictive substance. You go through a withdrawal symptom. But your body was
always geared to be, it should
never been in a glucose-addicted state in the first place. I agree. And then we look at the
state of America right now, and it's 94% of the population is metabolically unsound at this point,
I think. Oh, yeah. Well, it's not only in the United States, it's all over the world.
I think obesity has now replaced starvation as a number one health issue around the world.
Oh, that's really sad.
Yeah.
I mean, even in China, they have 200 million obese people.
I mean, it's like, you know, it's our diet.
You know, it's highly processed foods distributed around the globe.
Food has now, we used to call it locafors.
Most people would get food that would be grown
in their local area.
Okay, the butcher was right here.
He just killed the cow.
We got fresh meat.
We're growing our own tomatoes
and everything is right here.
We only occasionally go to the supermarket
to get something, but now everything is packaged,
highly processed.
And then you put that together with little exercise, stress,
sitting in traffic in the big cities, Chicago, New York City, Boston, you know, we're all sitting in
traffic. This guy cut us off. You know, the whole problem is convenient. You go home, you watch TV,
you work all day, you throw something in the microwave. It's just convenient.
You don't want to go out in the backyard and chop the head off a chicken and say, geez, I worked my ass off
all day, now I got to cut the head off this chicken for the family. Exactly. Yeah. I mean,
I've heard many people say this, but convenience is killing us. Yeah, yeah. And the more convenient,
I mean, even the removal of the stick shift on the car, the manual transmission was some X.
Now everybody has.
In fact, some people don't even know how to drive cars that have stick shifts anymore.
Some people just have cars that drive themselves now to do the Teslas.
I know.
It's amazing.
It really is pretty amazing.
And then they wonder why you weigh 400 pounds and you have diabetes and cancer.
Exactly.
It's no mystery here.
It's not a mystery.
It's actually perfectly predictable.
And it's getting worse.
It's not getting any better.
The more convenience we have, the more sickness we have.
So regarding your protocol.
I hate to laugh about it, but it's like. No, I get it.
It's so obvious that nobody understands this.
Or nobody wants to do anything about it.
I don't want to say nobody.
Of course there's people out there.
But, you know, when you have an obesity epidemic and you know obesity now has replaced smoking for a major risk factor, why would we see so much more obese?
Don't these people know?
Especially in children.
When you see little kids that are obese,
I mean, this is kind of a parental neglect.
These kids are not going to live as long on the planet as other people.
I think it's child abuse.
I really do.
I think it's child abuse.
I don't know if it's abuse because I would call it more neglect
because it's a lack of knowledge.
And if you have the knowledge, you would not allow
that to happen. And a lot of folks, listen, they're working hard and living paycheck to paycheck.
They don't have time to spend as much. They don't have time to listen. Be in their situation.
Look how hard it would be. So you're trying to hold them down two jobs for crying out
loud. You're just barely making it. And whatever you can eat is going to be highly processed. And
I mean, it's sad. I mean, it is. And I wanted to say too, we're obviously not laughing at people.
We're laughing at the irony of all of this, right? Is that it's so obvious. Yeah, right, right.
Exactly. That what we're doing right now is not working. And
the sad reality is there are a lot of people that either deal with a lack of knowledge, like you
said, or a lack of accessibility. You know, they're working two jobs. They're overworked.
Like you said, they're tired. They don't have the means for it. They don't have the money for it.
They don't have the time to spend in the kitchen. It really is heartbreaking the place that we're
at right now. I don't know the solution to it.
And I don't know if... It's, you know, and people live in food deserts
where they just don't have access to anything.
You know, it is...
And, you know, the federal government should do more,
but they don't.
100%.
You know, you always tell we got over too much.
We always say, oh, the government, the government, the government.
Well, there's certain things the government should do.
And then there's things that they shouldn't mess around with.
But if the population is getting so sick,
and in the United States Army, we're having problems trying to get,
a guy can't run.
They're too heavy.
Their bones are breaking.
It's like a national security issue here.
It is.
So, you know, something has to be done.
For sure. And I'm the same as you.
I'm like less government intervention, the better. But in this case, there does need to be something.
Something needs to be done. And we need to take the power out of these large food corporations
is really what it is. And not allow the lobbying in Washington and stop paying subsidies for crops
that we know are not better for our health.
Yeah, well, it's really interesting because it depends on what age you are
and what kind of stuff you watch on TV.
Like if you're watching sports, everything is Coca-Cola, pizzas, and hamburgers.
If you're watching the news in the evening, like ABC, CBS,
it's all these drugs to take care of all the ailments you had from eating the pizzas.
I was literally screaming at the TV recently. I was visiting my parents. I rarely watch TV where I see ads. And this ad popped up, and it was all about type 2 diabetes and this medication
for it. And then they're listing off all the side effects. I was literally screaming at the TV. I
was like, type 2 diabetes is not only preventable, but it's also reversible. You don't
need a drug for this. I know. But you know what it is? It's maddening. It's maddening. People want
to take a pill and they just want to take a shot and they don't want to do what I just said.
So again, it's the convenience factor. If I can give you a pill and you don't have to run and
exercise and don't eat carbohydrates, what do you want to do? I'm going to take the pill. Of course I'm going to take the pill, you know. Because then
you don't have to change your diet. Yeah. The cancer commercials spend more time telling you
how the drug is going to kill you than how it's going to help you. And yet the population doesn't
seem to be disturbed by this. You know, you sit there, you watch this guy riding his bike with
his wife or a friend,
and they're all smiling. And then they tell you 15 different ways about how this drug is going
to kill you. All the diarrhea, malaise, every kind of a thing. You know, why don't they show
you some guy sitting on the toilet when he takes the drug? It's like an SNL skit.
Blood coming out of his mouth and his eyes watering and all kinds of...
Here's what you get.
Well, it is crazy.
We truly have become...
And then they should say, and occasionally you might do better.
Exactly.
Occasionally it might actually work.
Well, we're so desensitized to this, and hopefully the listener knows this by now,
but the U.S. and New Zealand are the only two countries in the entire world
where they let the drug companies do commercials directly to the public.
Yeah, I know.
That's why we do these.
And then, you know, everybody demands them
from their doctor.
And even though they hear all the crazy side effects,
like the diarrhea and everything else,
it's like liver failure.
Yeah, they don't, I mean, you wouldn't,
can you imagine if someone came on a commercial
with a soft drink or a pizza?
It tastes really good, but there's 15 different ways that it'll kill you.
You know?
I wish.
You want to eat that pizza.
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slash RealFoodology. I'm really curious. So we've talked a lot about diet and obviously the
and lifestyle and how it affects our prediction to get cancer. What are your thoughts on,
I'm going to name off a couple of different things that I've been hearing about in the cancer world.
I've heard ivermectin. A lot of cancer patients are being put on, I'm gonna name off a couple of different things that I've been hearing about in the cancer world.
I've heard ivermectin,
a lot of cancer patients are being put on ivermectin,
also mistletoe and high dose vitamin C.
Do you think any of those work?
Well, the parasite medications will certainly work.
We know that, and we know that because when I did analysis,
I found out that the cancer cell,
they use mitochondrial substrate.
It's a way that the mitochondria can get energy without using oxygen.
It's an ancient form of energy.
It's very interesting.
Turns out parasites use the same pathway.
So when I use a parasite medication like ivermectin and bendazole, all these kinds of medications, it does a pretty good job killing tumor cells because they were made against parasites.
So, parasites have energy metabolism similar to cancer.
So, when you take the parasite medication and put it on the patient with cancer, And our mouse, we did preclinical studies.
We're doing it right now as we speak.
Here's the interesting thing.
Embendazole is a parasite medication.
And it was very cheap, maybe 25 cents, 30 cents a tablet.
It used to deworming in India.
A lot of people have them.
They use this embendazole, fenbendazole, a lot of people have them. They use this Fembendazole dog dewormer.
But as soon as they found out that at least Fembendazole for sure,
that it actually had some therapeutic benefit against cancer,
they jacked the price.
It's now extremely expensive.
Of course.
We call this Skirelli.
Remember that guy Martin Skirelli?
He was the most hated man in America.
Was he the one that jacked up the cancer cost by like 500%?
Yeah, it wasn't cancer.
It was like EpiPen or some other drugs.
Oh, yeah, the EpiPen was one of them.
There was a couple different drugs that did that.
Yeah, he did it because he could.
I mean, it wasn't like just to make a big profit.
Well, the drug companies are doing the same thing,
except they're not boasting about it and going in front of Congress, telling the congressmen how stupid they are,
you know, but they do basically the same thing. This is what I call immoral. This is not moral
behavior, okay? This is immoral behavior. And now we have another form of toxicity in cancer
that one of my students, we wrote a big paper on it here at Boston College,
called financial toxicity.
So you take people who have cancer
and they're living on paycheck to paycheck,
and then you say, oh, you have breast cancer, colon cancer,
and we're gonna give you this drug.
And the patient pays a lot,
even if the insurance company has 80%,
you're still paying 20% of $50,000 or a significant.
This puts the family into financial toxicity. Their whole economy inside the family's economy
collapses. And sometimes when the patient dies, they pass the bills on to the surviving people.
I mean, you talk about immorality. You talk about, and drug companies are making drugs that are so expensive that it's causing financial toxicity.
This is immoral.
There should be an outrage against this kind of behavior.
This is not normal behavior to do something like this.
But it's called financial toxicity.
So you say, oh, I went bald.
My gums are bleeding.
I have diarrhea.
I have malaise.
And now I'm broke.
And we found out that it increases divorces,
family break-aparts, and suicides.
Can you believe this?
From the financial taxi of trying to pay off an expensive bill,
and a lot of times the drug doesn't work.
Yeah, that's the other issue.
Yeah.
I mean, you tell me what's wrong with this picture, right?
Yeah.
I mean, and I would argue this is probably why there haven't been a lot of major advances in cancer
because they're also blocking a lot of this newer stuff coming out
because they know they can make so much money off of the chemotherapy and the radiation.
You can only hide the truth for so long.
I mean, I've published all these papers.
I mean, they're there.
Anybody who wants to read what I've written, it's not like I'm making this stuff up. I have published these papers. They're open
access in peer-reviewed journals. They can read them for themselves, and they can come to their
own conclusion about what they want to do. And if they have an open-minded oncologist, and I feel
bad because many oncologists are good folks. They want to do well by their patients. The
problem in the system keeps them locked into a standard of care that's not working. Okay.
We have 1,700 people a day dying from cancer in this country, 70 an hour, and it gets worse and
worse every year. I don't know if people know this. The American Cancer Society publishes these data every single year. Tells you
how many, over 600,000 a year from cancer, almost 1,700 a day, which is about 70 an hour. I mean,
people say, and the other thing too, is you get all these folks that are out there running to
raise money for cancer research. There's no accountability. No one of those runners and
jumpers and bikers are ever asking where the money goes. How come the more I raise money, the more cancer we get? It goes for
gene therapy. It goes for the same stupid things we're doing over and over again. If you want cancer
to continue, run for those societies, bike for those societies because you're contributing to
the problem. No one ever asks where the money goes because there's two theories driving this.
It's the somatic mutation gene theory and the mitochondrial metabolic theory.
And when the National Cancer Institute says cancer is a genetic disease, that means you're
raising money to perpetuate the problem.
It is not a genetic disease.
It's a mitochondrial metabolic disease.
You want to stop cancer, you got to target glucose and glutamine, transition the body
over to nutritional ketosis.
This is not what's happening.
And I feel bad for the, they're taking advantage of the goodwill of people to think that they're
doing something for their dead loved one or whatever, raising money.
Raising money for what?
You're raising money to perpetuate the very problem that we have.
It's unbelievable.
Exactly.
In every way.
Thank you.
I get very mad every time I'm at the grocery store or somewhere out and
they're like, do you want to donate to this cancer research thing or whatever? And every time I ask
myself the same thing, I'm like, where's all this money going? What are we doing with all this money?
It is infuriating. And I'm so glad you brought up the genetic component. So I, over the years,
have talked a lot about this on my podcast, the notion of epigenetics, which is essentially that only about 10% of your genetics actually play a role, and it's
mostly your diet and lifestyle.
And your genes can act as the bullet, right?
Yeah, your bullet.
And then the environmental factors are actually what pull the trigger and can eventually lead
to cancer.
I want to talk a little bit more about this
because I have a couple of girlfriends who are concerned
because they have the BRCA gene
and I've tried to explain this to them.
What would you say to somebody who's like,
I'm really concerned, I have the BRCA gene.
What are their actual chances of getting breast cancer?
Well, we've done a big dive on all these so-called
inherited germline mutations.
There's two forms of mutations that you find in cancer.
There's somatic mutations.
They're the ones that come from cell division.
They're collected in the tissue cells themselves.
And the others are germline.
You inherit them from within the family.
BRCA1, BRCA2, the leaf romani, P53.
There's several others.
Is the PIK3CA one of those? from any P53, there's several others.
Is the PIK3CA one of those?
I'd have to double check on that. PIK3CA, okay.
No, that's phosphatidylinositol 3-kinase.
That's a receptor on the surface of the cell.
We're talking about germline.
We're talking about germline things there.
Retinoblastoma, RB, there's a number of different germline things there.
Retinoblastoma, RB, there's a number of different germline mutations.
We've looked into all of them. So we have to say to ourselves, what are primary and what are secondary causes of cancer?
Let me give you an example.
Like Huntington's disease is a terrible neurodegenerative disease, okay?
People know about Huntington's disease tasax
disease these are called metabolic inborn genetic diseases when you have the gene uh you 100 you
will have the the affliction that's a primary cause so the huntington gene causes huntington's
disease 100 that is the cause there is no gene in cancer that's 100% penetrant.
Like the BRCA1 is about 50%. What does that mean? 50, 55%. A woman who has inherited the BRCA1 or
2 has about a 50, 55% chance of developing breast cancer, but not 100%. We're not really sure.
Same with P53 is very high. It's about 80%. But 20% of the people that have
it don't develop the cancer. And just like BRCA1, 45% to 50% of the women who have that never
develop cancer. So we call those secondary risk factors. And we found that when the BRCA1 causes
cancer, the BRCA1 damages mitochondria. It interrupts oxidative
phosphorylation, just what I said. You can have it from a BRCA1. You can have it from smoking,
occluded milk duct. You can have it from systemic inflammation. You can have it from any number of
things. These are all secondary risk factors. The primary risk factor is damage to oxidative
phosphorylation. So as I said, if you can keep your mitochondria healthy,
the probability of getting cancer is reduced. So a woman with BRCA1 can make really meaningful changes in diet and lifestyle, maintaining a level of therapeutic ketosis that would
significantly reduce the risk of cancer, even if they were to have that mutation.
So the radical, like I guess Angelina Jolie brought a lot of attention to this by having
breasts and ovaries and whatever else. There was a lot of surgical mutilation associated,
I mean, as a prophylactic. But that doesn't necessarily mean that mutation won't show up
in another organ at some point in the future. So the better thing to
do is radically change diet and lifestyle, thereby reducing the risk of getting cancer
from that secondary risk factor, which could be p53, BRCA1, retinoblastoma, RB, and all these
different other kinds of genetic, because none of them are 100 percent penetrant so that means they're secondary risk factors not primary risk factors so we've looked into all that and uh
so we're pretty pretty sure exactly how you how people get cancer it's chronic damage to oxidative
phosphorylation with a couple fermentation which otto warburg said years ago uh and we've just
fleshed out in a major way what he had been saying uh for for many years and we've just fleshed out in a major way what he had been saying for many years.
And we've just moved his hypothesis now we'd call a theory.
It's the mitochondrial metabolic theory of cancer.
It's not a genetic theory.
The genetic theory is no longer able to account for a lot of the phenomenon, whereas the mitochondrial metabolic theory can.
And when you change the theory under which you view the disease, major advances will happen.
As long as you're locked into the incorrect theory,
we're gonna perpetuate this cancer thing for decades.
Yeah.
Otto Warburg, the guy you just brought up,
he was a German scientist, right?
That kind of made some of these breakthroughs in cancer.
When was that?
It was in the 1920s, 30s, and 40s,
all the way up through the 50s. That's how I got into
this whole thing. I went back and started looking at Warburg because Linda Nebling, a PhD nursing
student at Case Western Reserve, took two little hopeless kids with high-grade gliomas, deadly
brain cancer, high-grade brain cancer cancer and she felt that she was reading
warburg who said glucose drives tumor why don't we give ketogenic diets to these little kids and see
they were both given up because they took radiation chemo surgical mutilation and they still
were the tumors were still advancing so she put them on a ketogenic diet. One kid eventually died, but survived much,
much longer than was predicted. And the other child was lost to follow-up, which means the
parents moved away. We don't know what the... But they both lived far, far longer. And then I tried
it on the glioblastomas that we have here in the mouse model, glioblastomas. And we found the same thing.
And I said, what the hell? So I started to do a dive on this and I said, wow, Warburg said all this. So then we started to, that's how we developed the glucose ketone index. Then we
started to realize, but Warburg didn't know anything about the glutamine problem. That's
our big, everybody knows glutamine. Everybody in the field knows glutamine is a driver
of dysregulated cell growth, but they think it, they don't know the mechanism by which it works.
And we're showing us a very different mechanism than what everybody else thought. It's a fermentable
mechanism, not an oxidative mechanism. And this is something very big new in the cancer world.
So the issue is, is once you understand what's going on, you have a choice to prevent it
and you now know how to manage it without toxicity.
So I'm really curious
because you keep bringing up the glutamine,
which is a huge part of all of this.
And I keep thinking about how I have a bunch of friends
that take amino acid supplements.
Like they take the essential amino acids
and they put them in their water every morning.
And I'm pretty sure there's glutamine in there too.
Would that be a risk factor for getting cancer um or does it not play that way no i don't
think it's a risk factor for getting cancer okay uh because we have a lot of weight lifters they
pop glutamine tablets to build muscle and everything um it's not a risk factor because
it's the number it's the most abundant amino acid in our body anyway it's very healthy our gut and our we need glutamine yeah it's really good for
me yeah if you have cancer consuming large amounts of glutamine is not good
it may not our preclinical our preclinical models where we have mice
that have brain cancer and then we cancer or metastatic cancer,
and we feed them large amounts of glutamine, it makes the tumor worse.
So we haven't published this yet. We're working on it right now, but we can see what's going on.
It definitely does not inhibit the cancer. If eaten, and don't forget we're eating,
it would be like somebody popping a lot of glutamine
tablets during the day. You take a bite of meat, you're going to get all the amino acids you're
going to need. Chicken, beef, pork, all this kind of stuff have plenty of amino acids in there.
A well-balanced diet with small amounts of food. Yeah, all this kind of stuff. Why you take
supplements? I mean mean unless the food
you're reading is deficient in many different ways you might have to supplement it which which might
have to be necessary but i i don't know what to say um but you know organic beef and don't forget
you don't eat much of this stuff um i know our people complain like chipotle they were complaining
the other day people felt they were getting gypped.
There was a portion.
They should be so lucky.
If Chipotle were really interested in people's health,
they would charge twice as much and give you less.
I talk about this all the time.
It's incredibly controversial, but this really imprinted in me.
When I was getting my master's in nutrition there was a study that we were shown
that um in they found this in rats that if you put them on a restricted caloric diet but it wasn't
so low that they were like you know starving and going crazy it was enough where they were like
satisfied and nourished and healthy but they they weren't overeating. They actually aged really well and they lived with more vitality and
they lived longer. And everybody's so obsessed with longevity. And I think that study was really,
I don't know, it really imprinted on me. And I thought that it was a great argument for finding
that perfect balance of eating enough food where you're nourished and you're not starving and you're able to get through
to the next meal without having to snack and eat all this.
It's basically about like not overeating
and not eating an excessive amount of calories.
It actually helps you with your longevity and with aging
and so many things with your health.
Yeah, well, that's, I mean, that's what we did.
We did all those calorie restriction studies here.
You did?
And we found out that it was blocking epileptic seizures and that's how we got into the cancer. And then we did it did all those calorie restriction studies here and then found out that it was
blocking epileptic seizures and that's how we got into the cancer and then we did it on the tumors
and not only that a 40 calorie restriction in a mouse uh would you give him 60 of what he would
normally eat which is somewhat what you're talking about um yeah we were able to show the blood
vessels of the tumor shrunk that The tumor cells started to die.
I mean, it was just a remarkable, powerful effect on the cancer.
And then, of course, then we started to apply more and more ways to make this work.
But aging, you die from the second law of thermodynamics, which is entropy.
Eventually, disorder occurs and things just break down with age I mean you don't live forever things everybody
is terminal to be honest with you just some some live longer than others but the mitochondrial
theory of aging is still quite recognized we die we die because we can't generate energy anymore
now of course if you get it fall off a, get hit by a car or something like this, it's totally different.
But if you age naturally, you die because your ability to generate energy dissipates with time.
Your mitochondria become less and less efficient in generating energy with time.
And you expire. We don't live forever.
But bad diets and lifestyles can accelerate that, increases entropy, disorder, and you die sooner.
You don't, you know, there's very, we looked the other day, we don't see many
morbidly obese people that live into their over 100. So, rarely if ever see, I'm not saying there isn't some 400 pound,
103 year old guy,
but I haven't heard about it.
Maybe you can do a search.
I've had my students look for somebody like that.
We can't find anybody.
At least nobody's on 60 minutes coming out and say.
Exactly.
Look, I just hit 360 pounds. Look at me, I'm five foot two, 360, and I just hit 360 pounds look at me i'm 5 foot 2 360 and i just said 103
years old i mean it's true though staying in a staying in a healthy weight a lot of people don't
want to talk about this but staying in a healthy weight is imperative for your health it's
imperative well it's all again a mitochondrial. And what do you do? You exercise.
Make sure you get plenty of exercise.
Sleep.
All the things that you shouldn't.
You have friends.
You get to sleep.
Eat natural foods.
Exercise.
You know, these kinds of things.
And you stay alive longer.
And maybe prevent cancer, too.
And cardiovascular.
And type 2 diabetes.
Hypertension.
High blood pressure.
All the chronic
alzheimer's yeah yeah alzheimer's is true i would say a good 40 percent of alzheimer's is due to
diet lifestyle uh there there are there are more genetic risk factors for alzheimer's um that we
know about that are that are pretty pretty bad uh but most of it is diet and lifestyle, just like cancer and type 2 diabetes
and all this other kind of stuff. So we're living longer, but not necessarily healthier.
With the Alzheimer's too, they're starting to call it type 3 diabetes, which is diabetes of
the brain essentially. Yeah. Well, it's interesting because the NIH came out with a
provocative question thing a few years ago, I guess, and it was like, how come people
with Alzheimer's have a lower risk for cancer? And it's because the neurons are starved of glucose.
The glucose transporters, you can't drive a dysregulated cancer if the glucose is low and
you can't get enough, you can't get the fuel into the cell. I mean, I don't know how close that's
been studied, but it was one of the provocative questions. How is it that people with Alzheimer's seem to have a lower risk for cancer?
A risk, and that doesn't mean people with dementia never get cancer, of course.
But they seem to be, because you said type 3, cancer needs a lot of glucose.
And in Alzheimer's disease, your neurons are starving and dying, okay, because they can't get enough glucose.
So what happens then, that's one part of the problem, not the whole part with Alzheimer's,
it's one of the parts. But you can't drive a dysregulated cancer without the sugar.
So in one case, there is a dying, but you're not going to drive a dysregulated cancer with
minimal or inability to take up sugar. So that could be
an interesting connection. But again, it's mostly diet and lifestyle. I think if people understand
that and act upon it, then they can reduce risks for a lot of these things. But man, I'll tell you,
I know what it's like. You ever eat a chalupa? They're delicious. They're great. And these Big Mac and all this kind of stuff.
I mean, they are engineered.
I mean, I don't care what people say.
I eat one like once a year or something.
Man, it's so damn good.
I have to sit there.
I said, damn, this is like so good.
I'm not one of these healthy.
Oh, no, I can't eat that.
Of course I can eat it.
You wash it out with a big beer.
You know, a big pizza with a beer.
What are you, kidding me?
You're not going to deprive yourself?
No.
But the issue is those are nice treats that we have developed over our technology, but now they've become so pervasive.
They have become part of our existence.
And part of every day. They're not treats anymore They have become part of our existence. And part of every day.
They're not treats anymore,
they're part of our nutrition.
And that could put us at risk, at risk, at risk.
Yeah, yeah, that's a big concern.
So you sort of mentioned this,
but I wanna get a little bit more concise on this
for people to really understand this.
So how do we keep our mitochondria healthy?
Because that seems to be kind of the concept out of all of this is that we need to keep our mitochondria healthy. So how do we keep our mitochondria healthy? Because that seems to be kind of the concept
out of all of this is that we need
to keep our mitochondria healthy.
So how do we do that?
Well, you have to do a lot of exercise.
You have to be exercising quite a bit, okay?
And I know a lot of people in society today
don't necessarily have that.
And then of course you get the nuts that are out there.
They're exercising so much,
they blow out their hips and their knees and all that stuff. And then they and stuff and then they it's not great around not doing anything, right?
I mean everything has to be done some level of moderation
and the older you get you're gonna know it for those young people that haven't haven't come to the
To the the fourth quarter of their existence on the planet
All of a sudden you thought you were doing, Hey, why doesn't that
work anymore? Jeez, that used to work. I know it doesn't. So, uh, and now the next thing you know,
you've got a hip replacement, a knee replacement, and he's sitting there with a cane, you know,
and then, but, but, but you're right. Yeah. Exercise. Um, and, uh, yeah, natural foods. I,
I, people all know this stuff. I mean, why should I have to say it? Yeah. It's just, but it's, the problem is it's hard.
It's just, there's so many other conveniences
that block us from doing this.
And they're so tasty.
I mean, damn, I know that.
Yeah, we all do.
You ever eat one of these jelly donuts
from the real donut shops?
I mean, we have up here in Maine, Condon's Donuts.
It's unbelievable.
I mean, you just tremble while you eat this big jelly donut or this crawler or whatever.
You say, how can man, human man, how can man make something that's so good?
And you have a nice big cup of coffee to go with it. I mean, this is like delicious stuff,
you know, pure maple syrup poured on a blueberry pancake. I mean, give me a break with a few bacon
slices on the side. I mean,
it's true. Are you going to deprive yourself of all this? No, no. The answer is no. But don't,
if you eat it every day, you might, you might worry about it. And I will add something to that.
So my philosophy is that if, as long as you're eating real food, you can really eat whatever you want. And what do I mean by that? When I first started on my journey of health and I started learning about all of this stuff
and prevention, and I knew that I really wanted to take care of my body, I wanted to prevent
things like cancer and cardiovascular disease and all that, I really started to realize
that it's more about the quality of the food.
So if I wanted a pizza, then I would make it at home.
Or I would go to a restaurant that has better for
you ingredients. Maybe they're importing the flour from Italy and they're using organic cheese and
they're making the marinara in-house instead of just pouring it out of a bag or whatever it is.
That really is my way of meeting myself in the middle to where I don't feel like I'm deprived.
I'm not depriving myself. My boyfriend and I probably have burgers maybe every two weeks. I make them at home though. I make them at home with organic grass-fed beef.
I make the potatoes from scratch. And that's kind of my workaround with all of this because you're
right. It is really hard and all these foods are so delicious. But I've gotten to this place now
where I would so much, I would pick a homemade burger from home over a burger from McDonald's
because those taste fake to me now. Yeah. Well, that's true. That's absolutely true.
But the other thing that's a real killer is this high fructose corn syrup.
That's a big one, yeah. That they pour in everything. I mean, anything,
you know, and highly, I love, here's my prop that I use in my class for highly processed foods,
this Twinkie box. Twinkies.
Yeah. These, listen, these Twinkies, see this Twinkie here,
it looks pretty good, right? Yeah. It's 10 years old. Oh God, that is gross. But also amazing that
you do that. Yeah. So it looks perfect. It looks a little stale, but generally it looks pretty good.
Last year, a mouse broke in and ripped through the bag and ate one.
So certainly he didn't certainly complain about it. Oh, also he might've felt really sick later.
But that's what I told Holly processed food. You put, it's full of, you know,
carbohydrates and all the chemicals they have in there. And now down the South, there was a bar down there where they deep fried the Twinkie and they put chocolate syrup and powdered sugar on top of it.
And all the young people pounding the beers and the whiskeys are all eating deep fried Twinkies.
Oh, God, it breaks my heart.
I'm like, oh.
Yeah, I think the workaround.
I know.
I think the workaround, to me at least, is to make more of that stuff at home or find restaurants that are using real food ingredients because then you don't feel like you're depriving yourself you know yeah
yeah no no but but you're right and this is the gauntlet that we all must walk through
uh you know we know that these are on oh they're unhealthy uh but i'm just going to try a little
bit i'm not saying listen i'm not i'm i'm not one of these health nuts. You know, I just do what I have to do to know what's going to, to balance what you need to do.
But it's hard.
I'm not saying.
But, you know, our goal here in our research is that, you know, once you have cancer, what are the therapies that you're going to use to manage the disease, to keep your body healthy, reduce the toxicity, and emerge from this healthier than when you
started. And I think more people on the planet are interested in that rather than all the things
they should have done not to get cancer in the first place. Once you have it, okay, now I got
to manage it. Can you manage it without toxicity? And the answer is absolutely. Can we use some of
the things that we have? Yeah, we can use some toxic chemicals, but we cut them way down in dosage.
So we constantly reduce toxicity, improve therapeutic efficacy.
And I think this is what most of the people would be happy to have.
So in other words, if you are diagnosed with cancer,
it should not be viewed as some traumatic death sentence,
but just a kind of
an inconvenience. Ah, crap, I got to cut down on my carbs. I got to do more exercise. I got to put
this thing and get it back under control. But metabolic therapy, a lot of it falls on the
shoulders of the patient. The patient is the primary driver of the process.
Today, the patient goes into the clinic and they're more or less a bystander
and they're treated with toxic chemicals,
radiation, surgical mutilations, and all this kind of stuff.
They're really not playing a role
in the management of their disorder.
Whereas with metabolic therapy,
you are a key player in this.
And if you're not the one playing, you know, you're not the one that's going to, the outcome may not be as favorable as you might think.
Yes.
Amen.
I love that.
I want to ask you one more question because I was thinking about this and I'm curious to know what your thoughts are around this.
So you had mentioned earlier Otto Warburg and these two patients that he was helping that were siblings, right? That both had cancer?
Oh, no, that was Linda Nebling. They weren't siblings. They were different kids.
Oh, they were different kids.
Yeah. And one of the nursing journals, we have the article.
Okay. So I misunderstood that. But what I was going to ask you was, you know, when we talk
about, because you're,
part of your message is that genetics really aren't the main driver of cancer. So how do you explain when somebody says like, oh, well, you know, my mom had it, my grandma had it, my aunt
had it. Do you think that a lot of that is because they grow up eating the same things in the same
kind of environment? How would you explain that? Yeah, I think it's, I think it's environmental.
They're common environment, generation after generation you're living in in a in a general
environment that's called you know it's an environmental issue you know it'd be one thing
if if all of your siblings moved to different parts of the country or the world and they were
all then to get and get the same cancer somewhere else then then you know that that may may have
something to do with a with a germline mutation or it could have been coming from their
childhood and then it's just showing up later yeah I mean that's true I mean but
the the issue of course is that it's usually common environment that that
that leads to that and it makes without knowing genetics, like we know, common environmental causes,
and that goes back to your epigenetic argument there.
I mean, there's a lot of things that can influence
how your mitochondria function.
And the mitochondria control the nucleus.
So the mitochondria are the most powerful
epigenetic system in our bodies.
They control the way the nucleus works. So when the mitochondria are the most powerful epigenetic system in our bodies. They control the way the nucleus works.
So when the mitochondria become defective and the cell now falls back on a fermentation mechanism,
the organelle that controls the life of the cell and the differentiated quiescent state,
that organelle becomes corrupted and this cell falls back on the ancient pathways of fermentation and proliferation
This is all linked evolutionarily to our to understand of life the origin of life on earth
so these so we know pretty much and they and and they're and they're driven by for these two fuels this fermentation metabolism and
when you go to the
Oncologists at the top medical centers no matter where you are
And you say this to them,
they have no, they never heard of it. So they just want to do what they've been programmed to do,
which is toxic poisons, radiation, surgical mutilation. So they, when you tell them,
listen, how am I going to target the two fuels driving the dysregulated growth of my tumor?
The poor guys, they never heard of this. They weren't trained in medical school.
So this, the medical school, the physicians coming through medical schools are simply not trained
to know how to use food as medicine.
They're not trained to know how we play one group of cells in the body off of another
group of cells.
When we know that, boy, I'm telling you, you're going to be super healthy.
At least you can do all this.
And the patient then becomes empowering to know how to do all this
so um yeah it's it's going to be exciting in the future right now i'm sorry to say we're on the
kind of the bot we're on the troth we're not we ain't going anywhere cancer is is getting worse
everybody's predicting it's going to get worse it's diet and lifestyle for sure uh they want to
make it believe it's genetics you You have no control over what happens.
No, that's completely untrue.
Unfortunately, the National Cancer Institute, I'm embarrassed to say that they have no clue.
And if they do, they're not telling anybody about it.
I'm publishing all these papers.
They say cancer is a genetic disease, 100 different kinds of disease.
No, it's not.
They all have the same problem.
We tested it.
We did it here on our lab.
We published these papers.
We look for fuels other than glucose and glutamine.
Can't find them.
We interrogate the tumor cells
to see what keeps them alive.
Then you know what keeps them alive
and you just take that away and they die.
I mean, it's just, we're doing all that ourselves.
That's incredible.
Well, what I just heard,
and I love to always end podcasts on a really positive note,
what I heard is that we can control a lot of this.
Not all of it, but a lot of it.
And to me, I found that incredibly empowering
because knowing that, one, that we know this,
thank God we know about these pathways
and that there's a clear path to helping.
If, God forbid, somebody listening
were to get a cancer diagnosis,
I would be just taking crazy notes during this whole podcast
and I would find a doctor who knows
how to treat cancer with diet and nutrition.
Well, unfortunately, you're not gonna find many of those.
And there's a lot of charlatans out there
that say they talk the talk, they have no clue.
They've never done the kinds of research that we do.
We're a mainstream knowledge base. We test the theories that underlie this. There's a lot of
guys out there that just take people because people lack knowledge. They don't have time to
look into the stuff that we do. And they just go and listen to this guy talks the talk. Even you
can go to MDN, you can go to the top cancer hospitals and they rush you into these treatments and there's not many.
And that's the big problem. I send out information to the patients, they get all fired up and they
go to their oncologist and get slapped down. And then they say, there's no evidence. This should
have been published. It is published. I just didn't read the articles. And there's the frustration is
that the patients get all excited and feel empowered.
They run down there and they get slapped down. They say, oh, no evidence. Who's telling you this?
This is all quackery and hoax. And I said, well, what number would you like me to change?
What study would you like me to bring different outcome for you? It's just like,
well, I didn't read that. And they have no time. I don't
want to make them feel bad. The issue is they got so many cancer patients. They're in there all day
long dealing with all these problems. They don't have time to sit down and look at the literature.
They should have learned that in medical school and they're not being trained. And that's where
the problem is. These poor guys, these oncologists are not being trained appropriately in these
medical schools.
Otherwise, they would know what I'm talking about and say, yes, we can put you on a diet drug program here where we can assure you that you're going to have a much better outcome, much less toxicity and improve your overall health.
They're not telling you that.
That's the tragedy.
How long is it going to take for that message to get out?
And I publish these papers. I do these podcasts, paper after paper, data after data, evidence after evidence,
and it falls on deaf ears. It's not the hospitals. They don't talk about it. The academic industry
is awarding grants to look at hunting for genes. It's not a genetic disease. The NIH is spending billions and
billions of dollars chasing stuff that has very little relevance to the patient in the clinic.
Nothing. It's unbelievable. And they don't seem to think there's anything wrong with that.
There's no accountability. Private foundations are running and jumping for cancer and then we
get more cancer. It's just unbelievable. And the patients never ask questions.
Where is my money going?
How come I spent all this money and nothing happens?
And some people say, oh, yeah, it's happening.
We have all these cancer survivors.
Many of them pay a serious price for surviving cancer.
They have hormonal imbalances, bone density imbalance, neuropsychiatric problems.
They have tissue mutilation problems. I mean, you're not getting
out of this guy. We can eliminate most of that stuff can be eliminated. It's through education
and knowledge and reading the scientific literature and looking at the data and coming
to your own conclusion. Look at the data. Let me see. Oh yeah. And then we have all these Brad and
Maggie Jones are doing a big documentary on our stuff called The Cancer Revolution.
They've been working on this documentary with Warburg and all the connections that I'm talking
about.
And they're getting a registry of all these so-called terminal stage four cancer patients
that are saying, hi, I'm Jeff.
I'm still here.
I'm doing well.
Hello, I'm Mary.
I was told I had three months to live.
I'm out, you know, three years.
I mean, we're getting more and
more of these so-called terminal cancer patients showing that when you do metabolic therapy,
you can in fact survive. Does that happen to everybody? No. But it happens to a significant
number of people that someone should say, what the hell is going on here? And that's what we're
looking forward to. I love that. And I love the rant that you just went on
because I share the same sentiments.
My only, I just, I have a lot of hope for the future
because I've been in this field for a long time
in the nutrition field and becoming an advocate
and a CEO of your own health for a really long time.
And for the first time in the last like 20 years
of me being in this world,
I'm really starting to see people
advocating for themselves, asking their doctors more questions, doing more research on their own,
finding other doctors when their first doctor says like, oh, I'm not testing for that or dismisses
them. So I do think that there's a shift happening, but you're right. There needs to be a massive
paradigm shift and more people need to become educated on what you're talking about
and unfortunately I think it's just gonna take time you know and people need
to share the podcast and yeah what we've done is we've we've separated the cancer
industry that we have breast cancer colon cancer lung cancer brain cancer
they all think they're different from each other and the NIH is supporting
that and that's wrong. All these
cancers are the same metabolically. They have the same metabolic problem. You have to unite the
tribes. The breast cancer people need to get together with the lung cancer, the brain cancer,
and the colon cancer groups. Organize the groups. Where are the organizers? You march on Washington
and you tell this cancer stuff has got to stop.
We are being victimized by a system that has no clue and they're off on the wrong theory about what it is.
So when you have the brain cancer, glucose and glutamine, colon cancer, glucose and glutamine, breast cancer, glucose and glutamine, bladder cancer, glucose and glutamine, none of them can burn fatty acids or ketones.
They're all very, very similar.
It just happens in a different organ, a different place so so it's all very similar we get people think they're all different so all of these things
have to come together before you're going to see a real a real paradigm a
sea change you know a paradigm shift this kind of thing a tipping point if
you will but it's happening it It will happen. There's no
question about it because you can't hide the truth for too long. Once you understand what I know,
it'll spread. It's just a matter of time. Yeah. Well, I'm so grateful for the work that
you're doing. And I'm so grateful that you're going on podcasts and spreading the word. I love
your Instagram. I told you this before we started recording, but a good friend of mine, Dr. Tina,
sent me your Instagram account. And I'm loving the work that you're doing. I'm loving following you. I hope
everyone listening will follow you. I guess before we go, I just want to give you a chance to say
anything else that you feel like maybe we didn't cover that the listener really needs to hear,
or maybe you can tell them how they can maybe get more involved in this.
Yeah, well, I think as long as our research keeps going and we keep publishing
and testing dosage timing and scheduling to improve the process, these advances will happen.
We get our support primarily from philanthropy and private foundations. So people donate to
the university through my name at Boston College here, and that supports our research and Travis Christopherson's foundation. So that keeps us going. And there are folks that donate to us because they want to be
part of the change rather than saying, oh, I can make a lot, a big, first of all, I'd love to know
who the guy is that can make a million dollars on this stuff that we're doing. Could be you.
I'd like to know that too, myself.
You know, a lot of what I'm saying doesn't really,
you can say, I have all these smart guys from Harvard
that come up here, right?
These young kids that are coming out
of the Harvard Business School or the BC Business School
or one of these, oh, I'm smart, I got, I wanna,
they come up here and they say,
oh, you got this cancer stuff that we're doing
is the greatest, we're gonna make a million.
I never hear from them again.
You know? Oh my gosh. They greatest. We're going to make a million. I never hear from them again.
Oh my gosh.
They can't figure out how to make a lot to replace the revenue
that we're currently generating from cancer
with metabolic therapy.
Ah, that's the guy.
That's the guy we want to look for.
Who's going to be the revenue guru,
the entrepreneur that's going to come in
and figure out how to,
my job is how long can I, can people
alive? This guy should have been dead. I'm really happy that he's living two more years than he
lived. I'll be looking. That's, that's, that's the reward, you know, but, but there, but you need
money to keep the program going and philanthropy and private foundations are doing it for us.
Anyway. That's amazing. Well, hopefully that entrepreneur that you're looking for,
maybe he or she's listening to this podcast so you never know yeah well we're always hoping and
believe me that's what happens i i we're very thankful for those folks that are making these
kinds of donations to us yeah and uh and we run another paper out another paper another paper
constantly building up upon the knowledge that we have that's's incredible. Where can people make a donation
or can we get a link or something to show notes
if they're interested in doing that?
Travis Christopherson's Foundation
for Cancer Metabolic Therapy has a 503 Foundation
and people make donations to our research to Travis.
And then right, biology department, Boston College,
there's a link there to make donations. It goes through the university and then the university supports our research through the
university itself. And people are making donations because they want to be part of this. And then
I send a kit of information out to cancer patients and say, if this information helps you and you
feel better and you're living longer, you might consider making a donation.
In other words, I don't charge anything for this stuff,
which is kind of, it's free.
But if it works, why don't you make a donation?
Yes.
You don't charge somebody for something that doesn't work.
They should make a donation if it does work, right?
That makes sense.
I agree, yeah.
Well, I'm so grateful for your time
and I really enjoyed this conversation a lot.
This was really fascinating.
I want to ask you a personal question
that I just ask all my guests at the very end.
And it's, what are your health non-negotiables?
So things that no matter how crazy your day is
or your week is,
you prioritize these for your own health.
Oh, well, you know, I'm here at the university
and right out behind my office, the biology department,
we have one of the greatest palatial gyms
that the university put together.
Forget about Gold's Gym and all these things you hear about.
I mean, we have, and all the young kids are in there
jumping around, you know, they all look,
they're all perfectly proportioned, body suits.
The guys and the girls, everybody looks like they came out of a health show.
You know, I go there every day.
That's amazing.
You got to move your body.
Oh, yeah.
You go walk around the reservoir, you go into the gym, just walking into that place.
When you're my age, you walk in there.
Oh, my God. Where can you go and see this kind of a view,
you know? But you do, I do that every day, you know, and, you know, so, and it makes,
it makes life enjoyable. Then you come back, work on killing cancer cells.
I love that. Well, please let everybody know where they can find you and they can find your work so hopefully
they can follow you on instagram and we already talked about where they can make the donations
but just anything you want to share as far as people getting a hold of you yeah well that's
those are the places i i would say and they could read my work on i just put my name open as and
publication scientific publications and then they can read all the stuff that i'm talking about
because i can't talk about everything in one of these short shows.
You know, we've got decades of research packed into what I'm saying.
So the details are in those papers and people can read them.
And I don't subscribe what you should.
People say, he didn't say what I should eat.
Only keep your GKI low.
That's all I can say.
You know, you can do that eating, whatever.
If it makes it go up, don't eat that.
Just that simple. Exactly. Anyway, Courtney, listen, I it makes it go up, don't eat that. Just that simple.
Exactly.
Anyway, Courtney, listen, I'll let you go.
Thank you for the interview and all the best.
Thank you so much.
I really appreciate you.
Thank you so much for listening to the Real Foodology podcast. This is a Wellness Loud production produced by Drake Peterson and mixed by Mike Fry.
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