Live Like a Girl with Dr. Mindy Pelz - How To Detox Your Body & Restore Mitochondrial Function - With Dr. John Lieurance

Episode Date: August 29, 2022

For full show notes, resources mentioned, and transcripts, go to: www.drmindypelz.com/ep136/. To enroll in Dr. Mindy's Fasting membership, go to: resetacademy.drmindypelz.com. This episode is about wh...y detox is so important and the best strategies for detox.  Naturopath & Chiropractic Neurologist has been in private practice for over 27 Years. Currently with Advanced Rejuvenation, a Multi-Disciplinary Clinic focusing on Alternative & Regenerative Medicine, Naturopathic Medicine, Chiropractic Functional Neurology, Functional Cranial Release (FCR), Lumomed, Lyme Disease, Mold Illness, and many other Neurological Conditions.  He is the Chief Scientific Officer of MitoZen Scientific, a cutting-edge healthcare technology company focusing on powerful delivery systems.  He is also the Founder of UltimateCellularReset.com, a web-based educational portal that sends weekly videos on health and wellness tools for overcoming disease, longevity, and vitality. He's contributed to and appeared on many media outlets and has been on the Documentary "Pain Revealed," ABC 7 news, SNN news, and popular podcasts like Ben Greenfield Fitness and CellTV with Dr. Dan Pompa.  Author of Melatonin: Miracle Molecule is working on his second book on endonasal cranial therapy. Developer of Functional Cranial Release and teach, as well as certify these methods to doctors around the world. Please see our medical disclaimer.

Transcript
Discussion (0)
Starting point is 00:00:00 I mean, you want to detox. You want to look at fasting. And what you're really doing when you're fasting is you're cleaning up cells. And some of the most important things to clean up are senescent cells, which are these zombie cells, right? Resetters, Dr. Mindy here. And I am on a mission to teach you just how powerful your body was built to be. This podcast is about giving you the power back and helping you believe in yourself again.
Starting point is 00:00:28 Let's jump in. On this episode of The Resetter podcast, I bring you Dr. John Lawrence. He's been here before, for those of you that have been listening to The Resetter podcast for the past several years. And I have brought him on to talk about melatonin in the past. He is one of the leading melatonin experts in the world. And he has a new book out on the molecule of melatonin that we'll leave a link to in the notes, which is phenomenal.
Starting point is 00:00:58 But in this episode, I really want to dive into detox and why detox is so important and what strategies there are out there for detox. Now, as you'll hear in this episode, detox is complicated. It is not as straightforward as drinking celery juice. It's not as straightforward as just taking some activated charcoal. You actually need to find the right rhythm for you. and women, as you will hear, especially in the back end of this conversation, we need to find the right detox rhythm for our hormones. So I wanted to bring Dr. John back on to talk about some of
Starting point is 00:01:40 the new cutting edge tools that he's using. We will talk about, as you will hear, we will talk about everything from why you would use a nasal spray for detox. And when would you use a suppository? when would you use an IV? How do you know if your supplements are working for you to detox? All the questions that many of you who are actively detoxing right now may have and want answers to. Now, I want to say one last thing on this episode because he is such a wizard. When it comes to chemistry and detox, nobody thinks to the depth of the level that Dr. John thinks of. and you will hear that we talk a lot about NAD. Now, you may be hearing NAD out in the world.
Starting point is 00:02:28 This is a hot topic. NAD drips are a hot topic. And I really wanted him to help us understand when would we use NAD. NAD drips are like thousands of dollars. I wanted to know, is it worth it? Is that something those of you that are contemplating an NAD drip? Should you be doing it? He's going to answer all of those questions.
Starting point is 00:02:51 So this was a really profound detox discussion that I honestly have never had with somebody before. So if you're curious about detox, you want to go deeper in your understanding of the mitochondria. You want to know where fasting fits into detox. You want to know what other tools there are for detox outside of supplements. This is the conversation for you. I am so excited to bring it to you. Dr. John Lawrence. And as always, if you love it, send it out into the world.
Starting point is 00:03:20 leave us a review, and I hope it moves your health forward. And I hope you enjoy it as much as I loved having this conversation with him. First I have to say, welcome back. A, I love talking to you, John. So thank you for coming. Oh, Mindy. I love talking to you too. Thanks for having me.
Starting point is 00:03:39 And what I love the most is you just don't know where the conversation's ever going to go. So, and that's the greatest thing because there's so much depth to your knowledge on all the topics around health. Yeah, thank you. Let's, here's a burning question that I think you're going to shed some really new light to. When I first started detoxing seven years ago or about maybe about 10 years ago when we started detoxing people, detox was very straightforward. Or at least it appeared to be very straightforward. It's not so straightforward anymore. And I feel like it's, it's because of this toxic world we live in, but also we have a lot of new tools.
Starting point is 00:04:18 So do you, are you finding in your clients? clinic in your world that detox is more complicated now than it's ever been and that we need better tools than ever before. Yes, absolutely. And, you know, when I first got into medicine, I remember that there was some clinicians talking the same story as far as how much difficult, how much more difficult it is to get patients well. I started out strictly as, you know, a chiropractor and eventually became a chiropractic neurologist and then went back to school and became a natural path. And so my path has just kind of continued to kind of expand. But in the, you know, in the early days, I do remember some of my colleagues that were just doing straight
Starting point is 00:05:05 chiropractic would say, hey, you know, I, particularly a clinician named his name's Michael Taylor. Are you familiar with Michael Taylor? He's in Oklahoma. And so he started the first chiropractic internist diplomate program, right? Cool. And he's really amazing. And so I started taking his course because I was interested in some of the laws that we're looking to change in Florida that would allow chiropractors to start injecting because I was interested in starting to reform prolotherapy and PRP because we're already doing it
Starting point is 00:05:41 in our office with other clinicians. And so I took that course. And in the beginning, I remember. really being very hesitant because I was in such a purist as a chiropractor. I really felt like, you know, I wanted to just focus on removing those interferences to the nervous system through adjusting patient spine and allowing that full expression of health and vitality to come forth with that skill. And then I was hearing from a lot of these other chiropractors that have been in practice for many years that that's just not working, you know, and they're having a
Starting point is 00:06:18 having to utilize things like IV nutrition and saunas and detox methods and a lot of different exotic healing modalities in order to get patients better, whereas before it was a lot simpler. Yeah. Yeah. I've been in so many chiropractic conversations like that of people who have been, you know, doing chiropractic work or body work in general for so many years. and everybody is saying the same thing. Like what used to work 25 years ago with body work no longer works anymore.
Starting point is 00:06:56 You have to bring in some ancillary strategies. So why do you think that is? Is that purely toxins? It feels like there has to be a bigger reason for that. Oh, it's for sure multifactorial. And some of the more prevalent concerns that I would have would be the amount of toxic load that our patients are carrying. And that would be both the man-made chemicals, as well as the biotoxins that a lot of people are exposed to. And then when you start
Starting point is 00:07:27 talking about things like mold and Lyme and Epstein Barr and some of these bugs, you have to bring in the conversation about how EMF is creating a much more virulent variety of these microbes, which may be compounding things. So you have a higher saturation of toxins. You have this more virulent infection. And so what does that, what does that mean? That means that there's going to be more inflammation in the body. And that inflammation is then going to cut down our cellular energy, which is then going to kind of compound the problem even further. Yeah. And I think EMFs is a really good, an interesting insight. And I want to dive into that because you have some cool strategies you've used to detox, taking that into consideration. What I want to make sure that that doesn't get
Starting point is 00:08:16 loss. This is like my major message in life is the body heals itself. And you and I have both grown up in the educational system through chiropractic and all our postgraduate work that believes a thousand percent in that. So when we look at what's happening to people today, whether it's parasites or Epstein bar or heavy metals, like why is the body not healing? Is it as simple as there's just too much insult to going on. There's too much physical stress, too much chemical stress, too much emotional stress. And then you put us in an EMF-filled world and our bucket gets tipped. Yeah. Well, you have to start talking about Hormesis when you start having this conversation and the hormetic window and the hormetic ceiling. And so this zone that everybody's able to
Starting point is 00:09:09 function at before they hit this inability, this inability to adapt is really, what we're talking about. And so when we have several stressors converging in that are stacking onto that, that, that, that, that, that, that, that, that, that, that, that, that, that, that, that, and book that we had a podcast before and we talked a lot about melatonin and we're probably going to speak a little bit more about it today because it's so important with this conversation because ultimately at a cellular level we have a resilience right and so this resilience is our ability to withstand inflammation to a certain extent before we shut down right and so I listened to a really great interview with a colleague of mine, Russell Ryder. He's an MD and a PhD, and he was interviewed on
Starting point is 00:10:14 Joe Morcola's podcast recently, and I'd recommend anybody going and listening to that because it was really good. And what I loved about that interview is that he really broke down this Warburg effect, which is the effect of inflammation shutting down our energy production at a cellular level. And where that energy happens is in the mitochondria. And so, Otto Warburg was a scientist that discovered that oxygen and cancer can't coexist and that there's this switching that happens when a cell hits that limited adaptation where it then switches into a much more primitive anaerobic glycolysis is the name of the way it's making energy versus aerobic. So it's with or without oxygen.
Starting point is 00:11:00 So when the cell makes energy with oxygen, it's a robust effect. it makes it without oxygen, it's about 10% as effective. And so what happens is these stacked stressors are causing ourselves to go into this inefficient way of making energy. And he points out very strongly about how this is what happens with cancer, but what's not recognized. And this is something that I'm going on to a lot of platforms. And I'm really trying to preach is that this is happening with almost all diseases.
Starting point is 00:11:34 And this is almost at the core of all diseases. And that's why your work with Dr. Compa's work, Benazotti speaks a lot about this. It's like we really are speaking the same language. We're just maybe saying it a little bit different. Whereas we're really trying to help people that are listening to us, our patients in the office, to find out which, how can they reduce these stressors, finding the stressor, reducing it so we can get that cell to start making energy efficiently so that you can express your health and vitality. the way that you're supposed to, the way that God meets you to. So the way I understand what you just said is that when the cell gets overloaded with physical,
Starting point is 00:12:19 emotional, chemical stress, those mitochondria start making a signaling molecule that tells all the other cells, hey, we're in danger, let's shut down ATP production, shut down all the natural detoxing of the cell. And so we go into this cellular danger response. And people can be locked there for years. And you could say, okay, I'm not feeling well. I have Epstein bar. Let me throw some supplements at it.
Starting point is 00:12:46 But really the root of this is to get to that core part of this cellular danger response. Is that what you're talking about? Absolutely. Right. And looking for the most effective and efficient things to start doing. Because, you know, for people that are sick, you know, if people are listening to this and they're not feeling well and they haven't for a long time, it can become very discouraging and disparative. And so getting some wins is really important. So I think looking at looking at your environment, looking at ways that you can eliminate toxins,
Starting point is 00:13:23 doing some toxic cleansing, not too aggressive. Drainage, I think, is really important. Oftentimes when we first start working with patients, we're looking at drainage. Homeopathy can be one of the best route. to do that because you want your body to be like letting this stuff go, right? And we do that through lymphatics. I like rebounding, breath work, exercising, walking. These types of things are important to kind of move our lymphatics and kind of get that river versus a swamp. You know, I talk a lot about that swamp versus river.
Starting point is 00:13:58 And so then what happens is we start to trigger some of these things to detox. We want to make sure we capture these things in the gut with different. binders. And I know you talk a lot about that. A lot of this stuff gets caught in the liver and the gallbladder in the gut and we need to kind of mop that up. But the more difficult areas are the deep cellular structures. And this is really primarily in the cell membranes. And so this is usually something that I start with patients a little bit after the first month or so. Usually my initial strategy with patients is to start looking at some antimicrobials, some gut parasite issues, some binders. But then one thing a lot of people aren't really talking about that I think is
Starting point is 00:14:44 really, really important. And I'm seeing a lot of people feel better pretty quickly with this is addressing the sinuses in the nasal passage, right? So having people do like what I call a 30-day sinus protocol. And we like using a product called glutistat, which has got emulsified oregano, sage, clove, bay leaf, glutathione, NAC, clodil silver, and some turpenes. So it's really got a lot of stuff in there. And so I'll have people spray twice and each side and do that four times a day for a month. If there's more kind of concern for in the respiratory track, I'll have them nebulize that same product but in a different form and kind of go between the two. And why the sinuses? Yeah, why the sinuses? You know, again, if I'm looking at somebody listening to the
Starting point is 00:15:37 podcast and they're like, I've tried everything, nothing's working, what, what, and then we start to open up pathways and then you go to what I hear is the second step is now let's go to the sinuses. Why the sinuses? Well, I like to call it doorways, right? I'd say you have to care for your doorways. And I look at the eyes, the nose, the mouth, and the intestinal tract through the anus. And so you have like probiotics and like dysbiosis that can occur in the gut there. But up in the head, you know, these are routes of inflammation. So it's been highly documented that the oral gingiva and the health of the mouth can make a profound impact on the amount of inflammation that we have in the body. And that gum disease or cancer,
Starting point is 00:16:26 cavitations in the mouth can trigger a lot of cardiovascular that can cause stroke, can cause a lot of digestive complaints. And probably a lot of the people listening to this are going to have that as a situation. So some of the easier places to kind of start with the mouth, the nose, and the eyes, we've created actually three products that address these doorways, one of which we actually launched just two days ago, which is called IRE. and all three of them are really interesting in the fact that they that they burn, right? So the glutostat.
Starting point is 00:17:05 You like the burning products. I see a trend. I do. And I'll explain why in a second. But the glutistat doesn't burn like the zen. Like we've talked about Zen. It's a meditation mist. But the glutostat does kind of have like a kick to it, like a wasabi kick.
Starting point is 00:17:25 The eyedrops, the iri is based on this Amazonian herb that's called Sonanga. And so there's a burn and there's also peppermin in there. And then with the mouth, there's a product called Boca Zen. Boca is Spanish for mouth. And it's got primarily oregano, cinnamon, and clove, right? And it's got some stevia and it kind of got some extra. flavor enhancing. So you put a half a dropper in the mouth, you move the tongue all around the gums, and then I'll have my patients take a toothpick and push it all between. And I have patients just leave
Starting point is 00:18:08 this in their car. And so on their way to work, they do the Bocazan, they do a couple of sprays. The eyedrops are more of something that you want to do when you're sitting and you're kind of silent. Now, what's really neat about these and the reason that the burning is important is because there's something called your autonomic nervous system. And this is probably one of the most important parts of your nervous system that you, that you can imagine because it's what drives all of the healing in your body, because it drives circulation, it drives your heartbeat, your digestion. It just controls your glands.
Starting point is 00:18:43 And so it's automatic, so it's not under your volitional control. And there's two sides to it. There's a sympathetic and a parasympathetic side. and the sympathetic is kind of that fight or flight it's a stress response which is mostly mediated by cortisol and then you have your parasympathetic which is resting and digesting and relaxing which is primarily mediated by melatonin okay and that part that's the melatonin part a lot of people don't realize right now that's that's interesting and there's also um a whole idea behind this extra pineal melatonin and that there's most of the melatonin produced in the body
Starting point is 00:19:25 is actually made in the mitochondria and it's in its existent in the mitochondria to allow for that hormetic window that we talked about earlier to extend out a little bit meaning that we can handle a little bit more inflammation without shutting down from from stressors so so with regards to this burning with the with the with the with the products you're stimulating something called the trigeminal nerve and we've been hardwired to have this connection between the trigeminal nerve and the vagus nerve because if we were to fall into like freezing cold water we have something called the dive reflex and so our when our face hits a really cold um fluid we have this calming effect it's this we have a shutdown our heartbeat slows
Starting point is 00:20:15 everything kind of slows down so that if we were in very cold water, we would be able to survive longer. So only the most important faculty is kind of stay going at a slow pace. So what that means is that we can use that to actually exercise the autonomics, primarily exercising the parasympathetic nervous system. Fascinating, because, you know, I've become obsessed with my chili pad in my bed. And I love my room cold because it relaxes me. So I hadn't realized that that was stimulating to the parasympathetic.
Starting point is 00:20:49 It's so fascinating. So one of the things I want to go back to what you just said, when we approach detox, like let's just use, you know, a lot of the stuff you do is so different than your typical detox, which is why you get such great results. And yet if somebody is really struggling with their health, what I heard you say is, okay, let's open up the lymphatics first, then let's go and look at the, the nasal at those three things that you just said, is it as simple as somebody can go get it off your website, they can start to use it, and now it's another level of detox that they're going to
Starting point is 00:21:26 experience, and are you going to see detox reactions? Are you going to see like some kind of Herc's reaction? Well, yes, there's a lot there. I was packed with a lot of information there. So let me see if I can kind of dissect that out. When you start doing, if you have a lot of microbes, so if you think about this, a lot of people aren't really practicing sinus and nasal hygiene. So when you start to spray something anti-microbial up there, you're going to have die off of things. And those things are going to then get into your system.
Starting point is 00:22:06 That's why you probably want a netty pot and really kind of cleared out, especially in the beginning. And so it is not. not uncommon for people to feel a little bad the first couple of days. And then afterwards, we'll generally hear people come back saying that they feel anywhere from 20 to 30 percent better just with that one strategy. That's crazy. And that quick, pretty quickly, if they come back to in a couple of days, that's pretty fast. Yeah. Pretty quickly, yeah. You know, the other, you were kind of asking about, you know, specific kind of protocols and strategies. You know, it's really difficult
Starting point is 00:22:43 for us to really put those things out into the public because of the regulations that are out there. So unfortunately, you know, you kind of have to be either like a coaching client of ours or, you know, I know you see some people and, you know, Dr. Pompa has a wonderful coaching program as well. So those are probably some things that people are going to want to start looking towards if they're really wanting to dive into some of these strategies. Yeah, I've decided in order to get well these days, if you like want to go into detox, you need somebody to lead you through it. It's hard when it's like so close to you. And there's like this whole underground like health movement.
Starting point is 00:23:27 And I'm going to like put you in that category of really cool products. But we can't because of the regulation, because of the way social media works, we can't talk about it. or we get, we get, you know, punished in whatever way, way that is. So, but what I love about your products and talk a little bit about this is, you know, I hear a lot from people like they're tired of taking supplements. And then I hear from other people or other professionals, supplements don't work because you're going directly into the gut dysbiosis. And you're going into, you're putting a nutrient into a dysfunctional gut.
Starting point is 00:24:08 But what I love about what you're doing is you're usually. using the eyes, you're using the nose, you're using the mouth, you're using the anus, like your suppositories are incredible. Can you talk about why those are incredible ways to get detox supplements or detox nutrients into your body? Yeah, well, there's two really interesting reasons with the, you know, with the suppository route of administration. One is that you're bypassing all of the digestive enzymes and stomach acid, which really can be very harsh on a lot of substances. And then you have this what's called first pass through the liver, which is the liver like filters. And that really breaks a lot of nutrients down. Sometimes so drastic, like with melatonin,
Starting point is 00:24:54 it literally breaks it down where you only get about one and a half percent absorption. And the other thing with an oral route of delivery, which is going to be this similar type of thing, with an IV is that you only have a certain window that the nutrients are available to the cell because ultimately the goal is to get the nutrient into the cells where it can do some work for you, right? And so the cell is constantly kind of feeling for what's outside in the medium outside the cell and pulling in what it can, right? And so if you take something and there's something called peak plasma, which is really a fancy word for saying how long a suburb. outside of the cell available to the cell, right?
Starting point is 00:25:38 Most times that's only about an hour. So if we were to take most supplements in a pill form, we'll have an hour or less where the cell has that available, where it can start pulling it in. And the cell has a rate that it can pull things in. And it's generally very slow. So if you were able to have that peak plasma lasts for five, six or seven hours, you can see that the cell would ultimately absorb a lot more
Starting point is 00:26:04 of that nutrient. And that's what a suppository also gives you. So not only do you avoid that first pass, but you're also getting this very long release where you have this slow bleed into the bloodstream where you get this long opportunity for the cells to actually pull those nutrients in. Yeah. I a thousand percent agree with what you just said largely because I'm seeing, we've detoxed using supplements, thousands of people.
Starting point is 00:26:32 And lately I've been getting some more, I don't want to call them extreme detox cases, but cases where there's a lot going on toxic load wise. And when we use your suppositories and we, I always joke and say when we come in the back door and we use suppositories, we get better results. Like literally, it's crazy. And people have to get past this idea that, you know, suppositories are awkward because for detox, they're magical. Well, one thing, too, is like some of the most amazing nutrients that I found clinically, especially working with fasting, because we do a lot of fasting. I mean, you want to detox. Yeah. You want to look at fasting.
Starting point is 00:27:14 And I know you're a big proponent with that as well. And what you're really doing when you're fasting is you're cleaning up cells. And some of the most important things to clean up are senescent cells, which are these zombie cells, right? So something called synolytics, which phyzotin and sterile-stil-stil-being, Quercetin, risveratrol. A lot of these are like these very colorful polyphenols from plants. They're not well absorbed. In fact, I mean, we just did a curcumin IV on a patient that requested it. And at the same time, we gave them a suppository of something called lucetol. And this lucetal is packed full of all of these polyphenols that are scinalytics. So I created a whole fasting protocol
Starting point is 00:27:58 basically surrounding that one product because it's so important and so beneficial to add a synolytic at the time that you're fasting. Now, you can do this just on intermittent fasting. So let's say, what hour? Yeah. Yeah. I mean, let's say you're skipping, you're skipping breakfast. You could take a lusitol in the morning, right? And then you could take it before bed because you're fasting at night and it would probably even carry through a little bit that next morning. if you're doing a 24 hour or a three or a four day fast, you can take the product two, three times a day if you want. And you're going to get this really important sinolitic effect
Starting point is 00:28:40 that I think can make a situation where you're going to get more out of the fast than if you were where it would be like doing a longer fast. And when you say more out of the fast, like we get this question all the time. People are like, how do I get more autophagy? How do I get rid of more of these senescent cells? Are you saying you're going to get wipe away more senescent cells? Well, there's so synolytics, that's what they do. Great.
Starting point is 00:29:06 So they taken just by themselves, if you were still eating, you're actually going to clear senescent cells by just taking these substances based on the research. So what we propose, we don't recommend, we actually will have people, we recommend here at our office, dosing different supplements based on the whole mTOR pathways, right, where it's like either feast or famine. Like, for instance, NAD is a better product to give to patients when they're eating, when they're an eating window, right? Oh, interesting.
Starting point is 00:29:41 And these anti-inflammatories are better to take with the fasting windows, right? So another really interesting molecule. that we've been having just amazing results with here in the clinic is methylene blue. Yeah, talk about that because I'm like on social media, I'm seeing people like show up with IVs that like are like liquid blue. And then I think you're talking about your Lomitol Blue product. I don't know if that's the same one. I know that we've experimented with that with some of the patients I've been working with. So talk about why that's so important.
Starting point is 00:30:22 Well, so we initially launched Lomitol. Blue as a 60 milligram and a 300 milligram suppository. And what we've done, and we were having people cut the 300 milligram suppository so that they could take it orally. And what that gave you is about a 75 milligram dose. And so what we've done is we just launched what's called the bar, the Lomitol Blue Bar, which makes it a lot easier to break it into pieces. And you can either take 40 milligram, 80 milligram, or you can cut it into whatever amount you want. And the Frank Gonzalez Lima is kind of considered one of the foremost with Methylene Blue. And any interview you can listen to online from him, I would highly recommend it.
Starting point is 00:31:12 It's really amazing to hear all of the things that Methylene Blue has been researched with. And it's similar to melatonin, you know, and if anybody's read my book on melatonin, you see like, there's a chapter on almost every disease. It's so well laid out, by the way, John. Like when I got it, I was like, wow. Like it's not just the information. It's the layout of it, the organization. So well, okay.
Starting point is 00:31:35 Thank you. Yeah. Well, I have an ebook on Methylene Blue as well. So we can make that available to your listeners and even do like a coupon. We'll do the coupon code Mindy. Normally it's like nine bucks or something like that, but we can do a free giveaway for that. Thank you. Appreciate it.
Starting point is 00:31:56 But so, you know, we're talking about how the body can heal itself, right? It just runs out of gas. It runs out of energy. And so things that can improve cellular energy like NAD, like melatonin, and like now we're talking about methylene blue, I really don't think that there's something stronger out there than methylene blue that can do that. And besides ramping up cellular energy, methylene blue has been shown to be antiviral. and in fact, the first use of it was against malaria and other parasites it's been shown to be
Starting point is 00:32:34 helpful for. And it leaves the body relatively unharmed, which is why there's a doctor Erlaki. You know, you've heard of Erlacki. It's a co-infection. That infection was named after this scientist Erlaki. And so he actually won the Nobel Prize, was very well. known in the late 1800s he coined the term magic bullet and he was actually referring to methylene blue. Interesting. Because it has so many profound effects. It's it's neuroprotectant.
Starting point is 00:33:07 In other words, they've done studies showing that if you have methylene blue on board and you have some sort of a neurological insult like a stroke or you have a TBI or something like that, it protects the nerves from being injured. If you have a heart attack and you have methylene blue on board, it's incredibly protective. In fact, every hospital has it in case there's cyanide poisoning because it protects the cell because it allows your cell to actually make energy independent of oxygen. And so a lot of these poisons rob the cell of oxygen and that's how they'll kill you. Yeah.
Starting point is 00:33:47 And is methylene blue a plant? Like what's the original source of it? So methylene blue is actually made synthetically. It's a, it's a, it's a, it's a salt. Okay. And I'm not normally a fan of of things that are, um, not completely natural, you know, and like melatonin is is a naturally occurring, um, hormone. And, um, this is different though. I mean, that's, we're talking about like 150 years of them making different molecules. And this was literally the first, um, synthetic drug ever approved by the FDA. And the patents run out.
Starting point is 00:34:27 So you don't hear about a lot because, you know, there's not a lot of money in companies to promote it. But there's nothing that has worked like this because literally when methylene blue gets into the mitochondria, which is what it has a great affinity for, it just goes and soaks right into your mitochondria. And that's why it's good for staining things that are like the brain or like there was a there was a there's a um a surgery where they were they removed the thymus gland when there's like
Starting point is 00:34:58 disease of the thymus and they give an iv of methylene blue and then they can see it really well right um so there's a lot of um effects for that so it goes to heart tissue and nerve tissue and any tissues that very that's very metabolically active because it goes into the mitochondria and then once it gets into the mitochondria it upregulates all four complexes. So in the mitochondria, you have four kind of stations that the energy is being produced. So it goes to the first one, the second one, the third one. And the fourth one is called the cytochrome. And cytochrome is cell and chrome is light, right? So this fourth stage is really interesting because you can actually put light into the cell in the sense of photons with like
Starting point is 00:35:48 red lights and near infrared light, which penetrates the best. So if you combine the methylene blue with a red light, you're going to get a really nice enhancement in all of those four stations. In fact, it's going to be somewhere in the neighborhood about 110% upregulation of energy. So you would want to do your lumetal blue suppository in front of your red light, is what I just heard. Yeah. So the suppository is something that's going to have a long, slow release. Right. So that's probably something you'd want to do a good 30 to 45 minutes before you
Starting point is 00:36:24 would get in front of any red light or in your sauna or going out into the sun. Oral route is probably going to be a little bit better. We had talked about this scientist, Lima, Dr. Lima, and his thoughts on the best way to take methylene blue is that when it's mixed with the stomach acid, it works really well. In fact, that might be a great way to do it. It's very convenient. He did not feel that the sublingual route was a very effective way and that the dosage on a lot of the available sublingual products wasn't really high enough. And so what we what we like is this suspension in palm oil that is thrown in the back of the throat and then you drink down so your mouth doesn't turn blue.
Starting point is 00:37:15 a lot of people don't like that, you know, that zombie blue look in their mouth. Yes, it's not a good look. Let me tell you. I've experimented with that look before. So here's what I hear and everything you're saying is that each nutrient has a different way it will be absorbed into the body. And we can't just, this is why you've come at this from so many different angles, is that we've got to know the nutrient, know what we're trying to.
Starting point is 00:37:45 trying to accomplish and then decide, is it going in the nose? Is it going in the eyes? Is it going in the mouth? Is it going to be a suppository? And experiment with the different entry points into the body because the gut isn't always the best way. Am I thinking this through right? Right. Exactly. Well, for any type of quantity of nutrients, you're going to want to first look at, you know, I would say a suppository may be even better than an IV, right? Because unless you're hooked up to an IV with a slow drip for five, six, seven hours, you're not going to have that long peak plasma, which really favors cellular absorption, right?
Starting point is 00:38:29 So then when you start looking at like nasal sprays, there's only so much you can spray up your nose, right? I mean, so nasal sprays can be really good for absorption, especially if you're looking at for something neurologically. You know, like we have an NAD nasal spray. You know, and that's probably one of our more popular products. But if you're looking for like full body systemic absorption of NAD versus neurologic, then I would look more towards the neuro-NAD suppository, or then I'm sorry, the NOMax
Starting point is 00:39:02 suppository. Right. So if I wanted to have more of a brain effect, then I would want to use more of a nasal spray. Whereas if I wanted more of a systemic effect, then a suppository would be better. Right, right. That makes perfect sense. NAD is really trendy right now. Oh, my gosh.
Starting point is 00:39:23 I feel like I'm hearing NAD drips everywhere. What do we need to know about NAD because it's expensive? Like, you know, if you're going to jump into it, you need to know what you're doing. Well, we were probably one of the first clinics to start doing IVs. I went to, I think it was in 2005, I went to San Diego and attended one of the first summits on NAD. And it was really, a lot of the science on NAD really came from addiction clinics because they found that a lot of these addicts, when they gave them NAD, they would be more social.
Starting point is 00:40:02 They were happier. It was a lot easier for them to maintain their sobriety. And so a lot of that information started to get out. out into the, you know, to the alternative medical circles. And so we were, we were literally charging $1,500. And I know there's a lot of clinics probably still doing that, $1,500 for a slow drip of, you know, about 1,000 milligrams of NAD. And patients would sit there.
Starting point is 00:40:29 They're a bit uncomfortable. Yeah, I was going to say, at that dosage, I'd be curious how they're feeling. Yeah. Well, you have to adjust the drip rate so that they can handle it. but they're still, you want them, they're going to have a little bit of symptoms. So you're, you're losing your day, you're uncomfortable, you're, it's expensive. And so that's why I think the suppository route is so much more, you mean, I, I, I, yesterday I had a patient come in and ask me if I would run an NAD IV on them and they were, you know, we charge a thousand to do this drip. And I,
Starting point is 00:41:05 I dissuaded them from it. And I suggested that they go ahead and start with the NAD max. Because Mindy, if you think about it, this is something you can do three times a day for like two months, right? You can really top off your NAD levels and then you can maintain it very easily that way. And depositories are such a no, it's like it's no big deal. It takes less than a, you don't even know it's there. You know, it turns into an oil. and you got that slow release.
Starting point is 00:41:35 And each suppository of the neuro-N-A-D, I'm sorry, N-D max, is 500 milligrams of NAD and then 250 milligrams of both precursors. Because there's a lot of controversy. I mean, some of the top experts with NAD even say that you're wasting your time, even doing an NAD IV because they don't think the NAD is actually getting into the cell and that it has to be a precursor like NMN or NR in order to make some sort of conversion to get into the cell. So what I've done is I've just kind of put them all together.
Starting point is 00:42:13 And we're getting some really good responses here in the clinic and a lot of reports from people and our practitioners. I have to tell a funny story about the first time I met you. And I don't think I told this the last time because I think I told the Zen spray. But then I was so, I love what you're up to. I call you a wizard. You're like, you're like a wizard with all this stuff. And I just geek out on all the different ways you're taking these unique substances and getting them into the body. So we were in a hallway.
Starting point is 00:42:43 I don't know if you remember this. And you were like, I think you might have given me a lumetal blue. And you're like, hey, suppository. You're like, try this. And I want to test everything on myself. So I was like, okay. I go to the bathroom. I put it in and then I sit down at the conference and I turn to Jessica and I'm like,
Starting point is 00:43:02 hey, I just got to give you a little heads up. Like, John just gave me something. So if something weird happens to be in the next couple of hours, I just went all in. Yeah. Yeah. Yeah. Yeah, that's how I roll. You know, I mean, people, you know, I travel a lot and, you know, at least a week or so.
Starting point is 00:43:24 I just got back from a two week vacation, actually. And, you know, it's like if you catch me in the beginning of my trip, I have a lot of product. I hand it out. I've been fortunate enough to be, you know, hanging out with some pretty amazing people. In fact, last weekend I was in Dallas treating Dana White, who is the CEO and one of the owners of UFC. That's awesome. And I've been doing these balloons on Dana, right? And it's like the fourth treatment that I've done on them.
Starting point is 00:43:54 and he made this comment to me, Mindy, afterwards. He said, this is one of the most, one of the best things I've ever done in my life because he couldn't breathe through his nose. And this is a new book that I've got coming out soon, and it's on endo-nasal balloon manipulations. I think we could do a whole podcast on it. Yeah. But it's this idea of expanding the nasal passage and opening,
Starting point is 00:44:24 up these cranial plates so that you can have a better movement of cranial rhythm. And this flushing of cerebral spinal fluid that kind of keeps the brain and spinal cord healthy is really, really important. It gets jammed up. And a lot of people become mouth breathers because they can't breathe their nose. Amazing. I wrote a whole book about this. And I'm really excited about it. And actually, so when I was with Dana, I knew that Mike Tyson was going to be at the fight that night. and he had invited me to go. And so I made a comment to him. I said, you know, what do you think?
Starting point is 00:44:58 You think Mike would do this treatment? And he said, oh, yeah. He said, I'll mention something to him. And they sat me literally like two seats away from Mike Tyson. So I'm like sitting there and I've got Mike Tyson to the right of me. I have Jason Witten from the Dallas Cowboys behind me. I mean, all these like crazy famous people. And I'm not really into the violence of fighting, but I could really appreciate what I
Starting point is 00:45:22 sensed is these these these fighters going into this complete now moment and almost being in some sort of a spiritual bliss you know in the middle of the ring there and so that was kind of what I was vibing but yeah fascinating so did you pull out your nasal did you just turn to mic and stick something up his nose well you know I didn't want to I'm going to let Dana kind of run on that you know, because I don't want to be like a salesman, but I would have said something to him if there was a situation that felt like there was a flow. And I missed my opportunity because I was doing a selfie. I had my camera out in front of me. And literally, while you watch this little clip, you see Mike Tyson walking behind me, he moves me out of the way. Right. And then in this little
Starting point is 00:46:15 selfie, I said, I put this on Instagram, by the way. So if anybody wants to go see this, they can go to my Instagram at Dr. Midazen at Instagram. And I move out of the way and I'm like, I just got ran over by Mike Tyson. It was so fun. Do you know, so when I was growing up, I always say that my mom was like ahead of her time. Like everything that she did with us was natural. And one of the things was when we were sick, we would get in the car and go the chiropractor and get adjusted. And his name was Dr. Acres. And he would do the, like, the worst thing would be like you'd see him pull that nasal thing out. And you'd be like, oh, no, here it comes. You know, I was like seven years old.
Starting point is 00:46:54 And he would do it up my nose. I put the air up my nose. It was horribly painful, but then your cold was gone. Like, it was just gone in that one treatment. So you knew the end result was great, but it's crazy therapy. Yeah. Well, you know, and that really makes a lot of sense, I think, for our discussion today. And why would you get better if you, because it always starts in the nasal passage, right?
Starting point is 00:47:18 A lot of colds and viruses and bacterial infections, it starts here and then it will seed down and it can get into your lungs and upper respiratory tract or it can get into your gut and then it goes systemic, right? Yeah. So that's why I love having something like the glutistat in my medicine cabinet or in my car or anywhere because, you know, as soon as you start to feel that and traveling is like I wouldn't travel without some sort of antimicrobial nasal spray. Because if you keep that healthy, everything really works really well. So when you had that balloon inflation, he changed you from that swampy to a rivery state and it just flushed everything out. Amazing. Amazing.
Starting point is 00:48:01 Well, the last thing I want to talk about is something that's actually on detox that I've been thinking a lot about. You know, you and Ben and Pompa and I was all strongly believe in cycling detox. And I've been trying to figure out how we would cycle detox to a woman's hormones. because what I know is when hormones come in very strongly, that that's actually a natural detox for a lot of women because it will release toxins from the tissues. Do you see that there's a proper time to time detox around a woman's hormones? Have you ever thought about that or experimented with that? Well, you know, I think methylation could be an important conversation to have through processes where there's more hormones because that's one of the primary ways we kind of clear.
Starting point is 00:48:47 our hormones, right? It's a detox pathway. I think that oftentimes I think blood sugar really plays a big role with a lot of hormonal problems. And so, you know, when you start to get into fasting, you start to have such a powerful regulation to those blood sugar issues and insulin resistance, which then leads to that whole host of hormonal concerns. So we look at that very carefully.
Starting point is 00:49:20 As far as like actually staging, like when would you do like an extended fast? Was that more of your question? Yeah. And I know around fast, yeah, I'm more interested in like when we go in with some of these things that are going to create a little more of a detox reaction. Like the NNA, like I've seen the lumetal blue create a little bit of a detox reaction in some of my patients. So I don't, I purposely don't put it in when I know the hormone, like during ovulation
Starting point is 00:49:45 or the week before their period. because there's too much going on then. Yeah, I think that's a good idea. Yeah. And then you might look at something like the methylmax. I know Dr. Pompa and I kind of work together to formulate that one product. And those are also nutrients that are very poorly absorbed orally. You know, your B vitamins, your folic acid, there's a whole bunch of other nutrients in
Starting point is 00:50:09 there that really don't get absorbed very well. And that methylmax, I find in combination with NAD to be a really nice. combination for a lot of different situations. But especially if you're looking for a kind of a better brain function or you're looking to have a day where you need to perform a little bit better or if you're looking to enhance kind of that phase of detox with methylation. Yeah. I love that.
Starting point is 00:50:38 You know what I want to do is what Fast like a Girl will come out in December. And we're looking once you understand the principles of hormones, you can time food and fasting, but I'd love to look at your products and go, okay, how do we time all these cool suppository sprays? Can we come in to help a woman create more estrogen and then can we use a different product to help clear the estrogen at a different part of her cycle? For women, I feel like that is the direction healthcare needs to go because we're in this crazy modern world that we're like an evolutionary mismatch to living in this chaotic space on this planet that we are. So I love what you're up to. And I'm thinking, how do we use it to support a woman's
Starting point is 00:51:22 natural cycle? And I don't know if you've ever thought about that, but I'd love to geek out on it with you. Well, you know, what comes to me as, you know, with all the wearable technology, you know, if there could be a device that could detect your hormone levels, right? Yes. Give you like, you know, and then you could program it to give you suggestions on, oh, it's time to methylate. You know, you just did two or three days of hardcore dumping of hormones. You know, let's clear those out. I think it's really next level thought process. I've asked several hormone experts how we could create that.
Starting point is 00:51:59 And everybody is a little unsure. Now, I will tell you what we're doing with Fast Like a Girl is we're going to create an app where we can start to time all of this for women so they can understand because most women are hormonal. Everybody's hormone illiterate except for those of us in the business. So it's a really interesting concept that I think the time is now for women to understand that where do we come in with these and where do we back off on this stuff. So I think you're the, I think you're the guy to solve that problem for me. Let's do it together. I love it.
Starting point is 00:52:33 You bring a lot to the table and I'm so respect all the knowledge that you've got when it comes to women's health. Yeah, thank you. Appreciate it. Awesome. Well, let me finish up on this thought. I think you were with me last year. So this season with the Resetter podcast, we've been focused on gratitude. I'm curious if you have a gratitude practice that you do every day. And if it is, what is it? And then, you know, we've gotten into this place where we have been just bitching and moaning about pandemic and politics. And I really want to highlight what people are grateful for. Is there anything that you're immensely grateful for right now? Well, yeah, I, I got a lot of things that I'm immensely grateful for.
Starting point is 00:53:17 And right now I'm grateful to be here talking to you and to be able to have the opportunity to reach out to all these thousands of people that are in your listenership. And I'm finding more and more that, you know, getting out of that place of wanting things, right? It's like the idea of desire. Like we want this, we want that. And then this idea of prayer, right, where we're petitioning, you know, may I have this, may I have that. And it kind of goes back to, I think, the original Aramaic Bible and Yeshua's teachings with with gratitude, right, and where you're grateful for already receiving this gift, right?
Starting point is 00:54:08 And so when we're when we're desiring something, this is basically putting out to the universe that there's lack. And it really makes sense, right? You want something? It means you don't have it. So you're sending lack out to the universe versus if you go into gratitude for already receiving it.
Starting point is 00:54:25 And I know this is a little shift because your question was more of like, no, I love this. Let's be grateful for what we have. Yes. But let's also be grateful for what we want, right? But then you shouldn't even say it that way, right? It's like because that's wanting.
Starting point is 00:54:39 Let's be grateful for what we're going to receive in the future. Yeah, you know, that I've studied on law of attraction and you introduced me to Rhonda Byrne and I'm so grateful for that for that interview is that there is an intention you set of this is how I'd like life to show up. Then there is a releasing of that and not being attached to it knowing it's going to show up. You just don't know how. And if I go to the feeling like what do I want to feel? Every day I set an intention on how I want to feel.
Starting point is 00:55:11 Sometimes it's joy, sometimes it's connection, sometimes it's playfulness. But I'm more interested in how I want to feel throughout the day than manipulating the circumstances in my life. And I feel like when we do that, it's much more, it's easier to be grateful. Yeah. And, you know, I think our true nature is happiness and love. It's like bliss. This is who we are.
Starting point is 00:55:35 And it's in that now moment that that exists. And our mind is what gets in the way because the mind. either in something in the future in the past, right? But the mind can never be in the current now moment. And that's really some of the work that I'm really focused on. I was actually with Rhonda, not last weekend, but she was one of the people that I went to go visit. And she literally took me to her teacher.
Starting point is 00:56:01 And such. Well, she doesn't say who he is or her. Yeah, it's a her. It's a her. She doesn't see people anymore. Yeah. She was interested in receiving the balloons. Wow.
Starting point is 00:56:14 So it was a really, really rare opportunity. And I was able to take a friend as well. And it was profound because these are people living in what we're talking about right now is one thing because it's all intellectual. But to bring that in and just completely own that you are happiness, that you are love and to remove all desire where you're just, it doesn't mean that you can't, you can't. have something that you think about, but you think about it, you let it go. And then it just, the universe just pulls it right into your life. So you can, you can have whatever you want. Yeah. So you just, you wind up wanting less, really, because you don't need it because you're in set, you're so full without people, places and things and so forth, you know.
Starting point is 00:57:01 You know, one of my favorite quotes is nothing fails like success. And why I love that quote is I I think once you see that you have everything that you need, your desires really change. And it's because you know that there's nothing you need to feel amazing. You can just feel amazing right now. So I love that. I love that. And next time you go to visit Rhonda, I want to come. So invite me.
Starting point is 00:57:28 I want to be on the invite list for that. I'm going in September. So, yeah. I'll be down in L.A. actually middle of September. So if you happen to go at that time, give me a good at that. Let's talk about it.
Starting point is 00:57:41 Let's talk about a conversation off. I would love that. I would love that. So how do people find you so they can get all these products if they choose to? Yeah. So our store is mitozhen.com, M-I-T-O-ZE-N. My Instagram is doctor spelled out mito-Zen. And we have a clinic in Sarasota, Florida.
Starting point is 00:58:04 It's advanced rejuvenation. dot us and that's it beautiful beautiful and i'm going to i'm going to hold you accountable to take all your products and time i'm to a woman's hormones so uh we i want to make sure we we connect on that before fast like a girl comes out because i think that would be so helpful for people so let's do it all right love it appreciate you john thank you as always you've just elevated my thoughts and opened my heart so thank you for your time today appreciate you're welcome indy thank you as well grateful for you. Yeah, me too. Back at you. Appreciate you. Thank you so much for joining me in today's episode. I love bringing thoughtful discussions about all things health to you. If you enjoyed it,
Starting point is 00:58:50 we'd love to know about it. So please leave us a review, share it with your friends, and let me know what your biggest takeaway is.

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