Live Like a Girl with Dr. Mindy Pelz - Your Brain on Ketones: The New Science Linking Metabolic Health, Mental Health, and the Power of Ketosis with Dr. Georgia Ede
Episode Date: April 8, 2026People with pre-diabetes are 2.7 times more likely to develop major depression. People with new bipolar disorder are 3.5 times more likely to have metabolic syndrome. If that stopped you in your track...s, good – it stopped me too. I brought Dr. Georgia Ede back to The Resetter Podcast to dig into her new expert consensus on ketogenic diets and mental health, and this conversation is one every woman needs to hear. Dr. Ede is a Harvard-trained psychiatrist and one of the world's leading experts in nutritional and metabolic psychiatry. What she laid out in this episode completely reframed how I think about brain health, brain energy, and what it actually means to feed your mind. We get into why the brain is a hybrid engine that runs best on a mixture of glucose and ketones and what happens when it runs on glucose alone. If you've ever wondered whether what you eat is affecting how you think, feel, and function – this one will give you the science and tools to find out. For more resources related to today's episode, visit the podcast episode page: https://www.drmindypelz.com/ep334 CONNECT WITH DR. GEORGIA EDE: Change Your Diet, Change Your Mind Instagram: @GeorgiaEdeMD Facebook: @GeorgiaEdeMD LinkedIn: @GeorgiaEdeMD X: @GeorgiaEdeMD CONNECT WITH DR. MINDY: Join Reset Academy Watch the episodes on YouTube Follow Dr. Mindy on Instagram Subscribe to Dr. Mindy's newsletter for tools and research on fasting, hormones, and metabolic health Disclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.
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On this episode of The Resetter podcast, I bring you back Dr. Georgia Edy.
So if you didn't hear her the first time, you're definitely going to want to hear her this time
because Georgia is a globally recognized expert in nutritional and metabolic psychiatry.
Her 25 plus years of clinical experience includes seven years at Harvard University,
where she was the first psychiatrist to offer nutrition,
based approaches to mental health conditions. She is also co-authored, and you're going to hear about
this in this episode, the first inpatient study of the ketogenic diet for serious mental illness.
And why I brought her back to you is twofold. One, so many of you are seeing a positive result
when you go into ketosis with your mental health, not just brain clarity,
But depression, anxiety, focus, it's like a miracle.
Just overnight, when you get into ketosis, you start to experience your brain in a different way.
And so much of what we have chat about here in my books on my YouTube channel is we think of fasting and ketosis as a tool for weight loss.
And yes, it's phenomenal for that.
But what I wanted to bring Georgia back for is to talk.
about how it's a tool for mental health.
There is a new expert consensus that she has published with some colleagues, which as you
will hear are the protocols.
I know how much you all love protocols, the protocols for ketosis to help mental health.
And you'll hear in this episode there was a reason they wanted to do this is they were finding
the ketogenic diet.
And when she says ketogenic diet, by the way, you'll hear us for.
flip in between fasting as a tool to get into the ketogenic diet and low carb as a tool to get into
the ketogenic state. And you'll hear at the end she lists all the different ways that you can get
into ketosis. But from a mental health perspective, she is the champion right now showing the
mental health world that along with whatever therapy they're using, whether it's drugs,
or it's something like EMDR or CBT,
some of the other clinical styles of addressing mental health,
there needs to be a pairing of ketones.
And it's really profound.
So so many of you, I know, are fasting,
you're working with carb cycling,
and what Georgia offers us is an incredible way
to look at ketones as a brain hero.
I definitely went into menopause, had to talk about it, had to talk about the brain rewirement.
And I think that many of you are not only going to see yourself in this conversation, but you're going to see your loved ones, especially those with cognitive decline.
I think if anybody's experienced depression right now, you need to listen to this.
She gives numbers.
She gives protocols.
It's a really powerful episode.
So excited to bring it to you, Dr. Georgia Eadie.
What would you give pre-diabetes?
Are you considering that like a 5.8 hemoglobin A1C level?
Like, do we have a measurement of what pre-diabetes is according to your expertise?
It's about the fasting glucose level.
So the fast and glucose level in pre-diabetes has to be above 110 milligrams per decedentator.
Okay. So if you, if, if, if, if, if, if, if, if you're, if, if, if, if you're, if, if, if, if, if you, it's, it's, it's very, it's very, it's very much based on the
fasting glucose level, which is unfortunate because the fasting glucose level is not a very good test for metabolic
problem. Right. Yes. Yes. Yeah, we probably.
We probably just freaked a few people, a few of my fasters out with that statistic.
So explain why it's not such a great measurement of metabolic health.
Yeah, because fasting glucose is one of the last dominoes to fall.
Right.
So by the time you're fasting glucose is high, you're already in trouble.
Right.
Because what's going on for years before that happens in the background, silently, without
anybody testing for it, unfortunately, is your body is producing more.
more and more insulin to keep your fasting glucose in a healthy range.
And it will do that for as long as it can until it can't do it anymore.
So it can be, so fasting glucose can be totally normal for years while in the background,
your insulin's going higher and higher and higher to keep that fasting glucose normal.
So a better test, a much better test for insulin resistance and metabolic health problem,
is a fasting insulin level.
Right.
That's a much more sensitive
and an earlier test
to see, you know, what's going on underneath.
And what would you want those levels to be at?
We have a lot of number watchers in this crew that listens.
So what would you want your fasting insulin to be at?
I mean, you really want it to be below 10.
Ideally, even six or less is better,
but in the single digits.
You want your fasting insulin to be in the single digits.
And it doesn't have to be there every single minute
of every single day. But the fasting insulin, if you say that above 10, that means that you are,
that you're producing too much insulin. Your body's having to work pretty hard to try to keep
your glucose levels in check. It means you're eating too much carbohydrate for your personal
metabolism for what your body can break down and actually do. Right. What's the mechanism
behind high glucose, high insulin, and depression?
So this is a topic of intense research.
So we have some theories that are being tested.
So for example, one of the theories that is very common in our field
is to think about mental health disorders as disorders of brain metabolism,
meaning that the brain is having trouble turning glucose, blood sugar,
into energy. So, and if the brain can't turn glucose into energy smoothly and reliably,
whenever it needs to, because the brain's a very high energy organ, it's an electrical organ.
So, and if it doesn't have access to smooth, clean, reliable flow of energy at all times,
then something's going to go wrong. So one of the theories is that depression is a reflection
of an energy shortage in the brain, that there isn't enough energy.
And so the brain is powering down.
You know, your energy goes down.
You know, you don't feel like doing anything.
You have no motivation.
You want to sleep all the time.
And so things like that.
So the brain doesn't have enough energy.
That's one of the theories.
Another theory is that there's a lot of inflammation going on in the brain.
And inflammation is very damaging to the brain and causes the brain to,
causes the brain to enter kind of a sickness mode where it wants to put you into bed and have you
rest until you feel better.
Right.
Smart.
It knows it's intuitively trying to get you to recover.
Exactly.
That's super smart.
So if the brain's energy powers down, does that mean, I know some neurotransmitters are actually
produced in the gut and some are produced in the brain, does that mean then it's also
can't be a factory for neurotransmitters that keep us focused and happy and well balanced?
So that's a great question. So yeah, the gut has its own nervous system and it produces a lot of neurotransmitters, but those neurotransmitters don't cross into the brain. The brain makes its own neurotransmitters. Great. And so, but that, the balance of those neurotransmitters, we're talking about things like serotonin and dopamine and norapinephrine and glutamate, lots of different neurotransmitters. The balance of the production of those neurotransmitters and
how well they work is strongly influenced, not just by how much energy is coming into the brain,
but also by how much sugar is coming into the brain.
Right.
So if you're eating too much, if your glucose is running too high too often, your blood sugar
is running too high too often, your brain sugar will also be running too high too often.
And that extra glucose inside the brain will, it has nowhere else to go.
It sticks.
It starts sticking to things inside the brain.
and that will set off waves of inflammation inside the brain.
And depression is very strongly associated with inflammation of the brain.
Yeah, fascinating.
And how many fuel sources does the brain have?
It has multiple fuel sources, but its favorite fuel sources are very small molecules,
primarily glucose, ketones, and to a lesser extent, lactic acid or lactate,
which we don't need to talk about today.
it'll get too complicated, but glucose is one of the brain's favorite fuels, but it really,
the brain has been described as a hybrid engine. It works best on a mixture of glucose and ketones,
because glucose is a fast fuel, so there's certain operations in the brain that need that fast energy.
Ketones are a slower fuel, slower burning fuel, but they're cleaner and they're smoother,
and they're more efficient and they cause less inflammation and oxy of stress when you're burning
them. So it's really a combination of the two that works best.
And what, like if I have a hybrid car and the, I'm not doing anything to facilitate the electrical,
the, you know, the electric part of it, I'm only working on the gas. It seems like I wouldn't be
using the car to its full capability. So as I'm hearing you talk, I'm thinking about the
millions of people that never have really experienced the power of a ketone. What would happen to the brain
if it never got exposed to ketones and it was only exposed to glucose? Does that cause any inflammation
because it doesn't have that second fuel source or any challenges to the brain?
100%. So if your brain tries to run entirely on glucose, first of all, it would be very,
very difficult for that to occur because you would have to be glucose doesn't last very long.
You have to keep putting it in.
You have to keep it.
So like for example, overnight when you're not eating carbohydrate, unless you're fat adapt and
on a ketogenic diet, overnight your body will say, we're running out of glucose,
we're running out of glucose.
And your body and your brain will try to then switch over to ketones to bridge that
energy gap, but that takes a little bit of time. And so what's happening is that there's a stressful
transition period overnight where cortisol levels can go up and people can actually wake up or
their sleep can be disrupted because they've got this surge of stress hormones that are trying to,
they're looking for energy. Where's the energy for the brain as the glucose is dropping overnight?
Right. So having a smooth, having your body be metabolically healthy means that you can switch easily and efficiently between the two.
And most of us are not metabolically flexible anymore. And it's hard to regain that. You can regain it, but it's hard to do. And it takes some time to rebuild that flexibility.
But most people are trying to fuel their brains almost entirely with glucose. Right. And that's, so a couple of problems with that.
One is that your energy level is going to be unstable.
Right.
And the other is that glucose, it does burn faster, but it doesn't burn as cleanly or efficiently.
And so what you get is you can get more inflammation and more of something called oxidative stress.
And these are damaging forces in the brain.
So if you're running on glucose all the time, it's like you've got your foot on the gas pedal and you're really damaging the engine.
What you want to do is you want to occasionally take.
your foot off that gas pedal and and give your brain some some down time, some time in a lower
glucose state. Not a zero glucose state. You always need some glucose. Of course. But you want to,
but if you're trying to run 100% on glucose, you're really going to have to keep that foot on the gas
pedal to get enough energy. Whereas you can let up and let the, let the ketones do some of that
work for you. And that way, when you're in ketosis, the brain can enter a,
a healing mode where you can recycle, you can regenerate, you can you can build and repair and
clean up. If you're running on glucose all the time, your cells are too busy processing that
glucose for them to actually do maintenance and repair and healing work. And so I'm thinking in
application of what you just said, would it be to my brain's benefit to maybe eat an earlier
dinner, maybe even a dinner that's more stable for my blood sugar, knowing that I'm hoping to go
into a mild state of what I refer to as nutritional ketosis when I'm sleeping.
Like, would that be the goal of brain repair is to have everybody be in a metabolic state
where they can flip into ketosis when they're asleep?
That is the way I think about it.
I believe that everybody, whether they have a mental health condition right now or not,
or whether they have metabolic problems right now or not,
even people who are robustly, mentally and physically healthy,
which are very few of us, unfortunately.
Very few, I know.
You know, but even if you are in the, if you're right now the picture of health,
it's still, this is my opinion based on, you know, what I've studied,
I think it's still ideal for humans who want to maintain their good health
to get into ketosis on a regular basis, especially overnight.
It doesn't mean you have to be in ketosis all the time.
It doesn't mean you have to even eat a ketogenic diet.
It's just about making sure you're using those pathways
and keeping those pathways well-oiled and well-used
so that you can flip back and forth easily so that everything stays in working order.
So that you enter this healing mode every night.
Overnight is the perfect time to do it.
And so overnight, going to that healing mode, and then the next day, eating in a way that doesn't spike your glucose into unhealthy ranges. And again, that doesn't necessarily mean a ketogenic diet. It depends on who you are. So I agree with you that getting into ketosis overnight, even just mild ketosis overnight, is really beneficial for everyone.
Yeah, I've been really, you know, when I started to really understand melatonin, I saw that there's an inverse
relationship between melatonin and insulin. And so, you know, from a weight loss standpoint, I really
started teaching people that they shouldn't eat right before they go to sleep because, especially
if it's dark out, you've got, you know, you've got a lot of melatonin going in you, which makes you
a little more insulin resistance. Yes. It's really, and then I just recently saw another study that was
showing improved heart rate variability if people didn't eat three hours before they went to bed.
It was easier on the nervous system, the cardiovascular system. So I feel like we're just getting
this arsenal of don't eat before you go to bed. Don't eat when it's dark out. You know,
and so we have a circadian rhythm just like all creatures do. And, you know, we metabolize our food best
during daylight hours.
And so once it gets dark, you're going to become more insulin resistant.
And so that's when you're going to tend to store more of your calories as fat.
And it's just not going to be as healthy for you.
And you're going to lose out on that precious overnight healing phase that I think
one of the holy grills of good health.
So, so amazing.
And we're over here telling people that sleep is so important, but we're forgetting the nuance of
like sleep is really important and here's some factors to get you the most out of your sleep,
which food timing would be a big one.
In this new expert consensus, there was a couple of things that were really interesting to me.
So one was that you all decided what the amount of ketones that was best for depression,
schizophrenia, and dementia.
Is that correct?
those were the three conditions you looked at?
So this paper, the expert consensus was eight of us who have many years of experience
studying and using ketogenic diets and mental health.
We were asked this question and tried to come up with an answer.
And we focused on what are often called serious mental illnesses, which are major
depression, bipolar disorder, and schizophrenia.
So those three major mental illnesses were the ones that we focused on in this expert consensus.
And so now we don't know for sure what is going to be the right range of or level of ketosis
for every person with one of these conditions.
But what we said in this paper was that based on our clinical experience and the research
that we have available so far, it appears there appears to be a trend.
where with these serious mental illnesses, most people seem to do better when their degree of ketosis,
their range of ketosis is somewhere between 1.0 millymol per liter and 3.0 millymol per liter most of the time.
It doesn't have to be all the time. Ketons fluctuate. They naturally fluctuate quite a bit.
And we've all seen all of us on this panel had seen people respond to lower levels and seen
and seeing some people need higher levels, but most of what we tend to see, people tend to do better
when they're in that range. And so we ask people to aim for that range at first, and then they can
find out for themselves what their personal, optimal range is after they've gotten into good
consistent ketosis for a while, see whether they can loosen it up a little bit or whether they
have to actually tighten it up. But between one and three is a nice window to aim for.
Which is so beautiful because I get asked all the time from fasters.
You know, when people start fasting, they're like, oh my God, my ketones were 4.0, 5.0.
And I'm always like, look, I've sat with so many ketogenic experts.
None of them are going for the more is better.
In fact, I've sat in so many conferences where people say 1.5 is my sweet spot.
It's where I feel my best.
So I think it's really interesting that you gave that range because there is what I
seen on my end is this desire to get more. But do we know if more is better? We don't know that.
I can say that if ketones are too high for too long, you're kind of edging into starvation range
and nutrient deficiencies and so forth. But most people are not using fasting in that way.
Most people are not using a ketogenic diet in that way. So those are kind of more extreme situations.
But with intermittent fasting and with a properly formulated ketogenic diet, getting a, you
getting into that range is not, it is, is considered, is considered ideal by a lot of people,
but there are some people who do feel better when they're even higher. Some people feel better
when they're 3.5 or 4. And, and, but, but I have many patients who feel quite uncomfortable
when their ketones are running too high for too long. Um, this would feel anxious, can't sleep.
They're hungry all the time, can't concentrate. Um, and, and that, and usually that's,
because they're not getting enough of something they need.
And so it depends on, it depends on the devil's in the details.
But I've also seen people who respond to a low carbohydrate diet and maybe a little intermittent
fasting where they're never really in great ketosis, but they're just so much better anyway
because they've gotten their glucose levels under nice and low and stable, right?
So sometimes that's all you have to do.
And sometimes all you have to do is just give yourself a break from food processing.
Yes.
Yes, well said.
It's so hard on the body and brain.
Yeah.
Yeah.
And so the other interesting thing I found about this consensus was there are some
recommendation.
Now I understand we're talking about severe depression and some severe mental health conditions.
But the recommendation was four to six weeks consistently.
did I read that right with these 1.0 to 3.0 ketones. My first question was how did you how did you get people to stay at that level for four to six weeks?
Right. So most of us agreed that you wanted to give it at least six weeks in relatively consistent ketosis. And in some cases, you're going to need a little bit longer than that. So what I see in my practice and many of us have seen is that there,
When somebody with a mental health issue starts a ketogenic diet, what I like to say is three days,
three weeks, three months.
Some people feel better in three days.
Some people it's going to take more like three weeks.
And then there are a few outliers where they're going to have to go a whole three months
to really see to turn that corner.
That's not very common.
But for people who really have a sticky mental health problem, they might need to, you know,
just to make sure it's not going to work to give it a good.
three months before you decide it's not going to work for you.
Yeah.
So, but most people within three weeks will respond, but we say give it a good six.
And so how do you get people to stay?
This is, I love this question.
Yeah, exactly.
That was like compliance for that long is got to be really interesting.
You know, it is.
So it's a real issue.
Adherence to these diets is a real issue, especially in the very beginning.
So anybody who's tried a ketogenic diet for a few days are like, oh, it's so hard.
how am I ever going to stay on this? But those who make it who make it past the adaptation phase,
especially if you can get to week three, it becomes so much easier because all of your pathways
have shifted into a different mode of operation. So your appetite is under better control. You've got
good energy flow to your brain. Your cells are adapting to using more fat for energy and less glucose. They're
still using glucose, but they're using less glucose, and now they're using a mixture of fuels.
So everything's quieting down. You've found a kind of a new equilibrium. Your cortisol levels
have come down. Your acid-based balance has corrected itself. And your electrolyte imbalances,
which can happen in the beginning, have sorted themselves out. So your body's adapted to this new
mixture of fuels and becomes happy and content. Yeah. And it wants that now. It wants that now. It's
just like, you know, I have had some patients try extended fasting, and they have all said to me,
without exception, get to day three. You get to day three, suddenly it's like, oh, I could do this
for another week. We do. Every January, we lead a worldwide fast and we get 100,000 people to do a
three-day water fast. Wow. And it's so fun because people are like, you know, I always say on day one,
tell me what you're feeling, just get it out. And then by day three, I'm like, now tell me what you're
feeling. There's so much apprehension. And then on the other side, people are like, I couldn't
believe I did that. I can't believe how easy it was. Can I keep going? There is something about
priming the metabolic switch that does not get enough credit. And outside of like other diets,
it gets easier with time. When you're well adapted to a properly formulated ketogenic diet,
it feels so much easier than trying to walk this tight robe of how much carbohydrate can I have
and what types and all that kind of thing, which can be so challenging, especially for people
with carbohydrate addiction issues, which are fairly common. It can be hard to moderate. And so
that kind of being completely on the other side where you're in ketosis, it's just, it's easier.
There's a great study by Dr. Ian Campbell.
He's a researcher at the University of Edinburgh in Scotland who,
eight years ago,
he was a musician in Scotland, a very good one and talented.
And he had bipolar disorder and he hadn't found anything that helped him.
And so he was overweight and he's like, well, you know, I can't fix my mental health.
Why don't I try to lose some weight?
I can at least try to lose some weight.
So he went on the Atkins diet, and he, within three days, his bipolar depression started to live.
And he was like, oh, that's interesting.
So, and he tested this over and over and over again and then started learning about ketogenic diets.
And then he went back to school, got a PhD.
And now he's one of the world's leading researchers in the field studying ketogenic diets for bipolar disorder.
Wow.
And I tell you this story, because you asked, you know, isn't it hard to stick on, stick to the diet?
So he published a study where 20 people with bipolar disorder tried a ketogenic diet because people said,
oh, you know, people with mental health disorders, they're not going to be able to do this.
It's going to be too hard.
And he said, well, let's find out.
So 20 people with bipolar disorder, they were able to get into great ketosis.
They were able to measure their ketones every day.
Their levels were about 1.3 on average, which is nice, above 1.0.
and then so they did wonderful and their mood and their energy and their and anxiety and so forth
improved the higher their ketones were they seemed to do better the higher their ketones were
but the thing that was really great about this one of the many things that was great about this study
was that after the the study was over there was supposed to be a washout period where
the researchers were supposed to help people wean off the diet
that was part of the protocol.
Seven of them refused to come off.
I bet.
I wondered if you were going there.
Yep.
Yeah, they were like, we know, we feel too good.
We're not doing it.
Yeah.
You know, I always tell the story that when I did the last, two times ago, I do a three-day water fast, usually once or twice a year.
And the last time, a couple times ago, one of my closest friends knows me enough and was like,
are you on a fast? You're really, you're so happy today. And you're so, you know, you're so clear-headed.
I'm like, oh, yeah, third day. She goes, I could tell it was almost like you were on cocaine or something.
I'm like, yeah, that's how it feels when you've really tapped into that. So it's quite remarkable.
It really is. There's a strong connection between how we eat and how we feel. And other people can feel it too.
So in terms of just your outlook on life, your tone, your facial expressions, your energy,
kind of the energy you put onto the world, how you roll with things.
And I can tell when I'm working with patients, I can tell as soon as we get on screen,
because I do, I work almost entirely virtually now, I can tell within 10 seconds if they're
on plan or off plan.
Because by how they're holding themselves, their look on their face, their tone of voice.
And so it really is a lot more powerful than people realize.
You bring up a really interesting point because when I had my clinic and I started teaching fasting,
I could literally tell when the person walked in the door and was sitting in my waiting room
if they were in a state of ketosis.
And I would look at them and I'd be like, you're doing it, aren't you?
You're fast?
because I taught it through fasting and then I taught carb cycling and all kinds of changes to it.
But you could see it in them.
It's like on one hand they can't lie to you because you can see if they're not doing it.
But then on the other hand, just to look across the room, you could see the vibrancy
and the alertness and the happiness.
And this is where when people start to break the ketogenic diet down or even fasting down,
I'm like, you've got to try it.
And then you come back and tell me how it feels because there's no drug on the planet that can give you that lift like ketones do.
Thank you for saying that.
That is a great point.
And we talked a lot about this last time I was on with you is how many, many, many of the same or similar benefits from fasting and ketogenic diets is that you're in ketosis in both of those cases.
Right.
And so the ketones are being in ketosis is a different state of mind.
mind. It's a different state of mind. It's a superior state of mind. Yeah. Thank you. You said it. I think so too. I think so too. It really is. People feel
better, they sound better, they get more done, they are better able to deal with stress, better able
to recover from, from difficult events in their lives. And so, I mean, person after person
after person that I've worked with us told me, you know, it's not like my life changed. I mean,
I'm still in, I still have a difficult relationship, or I'm still having trouble at work,
or my kid is still sick, whatever it is, but I don't feel the same way about it. I can step
back from it and I can get get get have like a buffer and I can think through okay how am I going to
how am I going to work with this today and you start to imagine more options you feel more flexible
in your thinking and you feel more capable you feel more confident and you're less likely to
let things really get you down agreed agreed did your grip look at ketones compared to
medications at all have we done those kind of analysis not really really
No. But so, I mean, you can look at them separately, but they haven't been compared head-to-head.
So we don't yet have any studies where you take a group of people with a mental health condition.
Let's say you take a group of people with major depression and you put half of them on a medication and you put half them on a key to treatment.
We haven't done that yet.
So, but what we can, what has been done, for example, is in fact, in just about every study that's been published in the field of metabolic psychiatry,
this field that we're in, is in almost every case, whether it's been a clinical study or whether
it's been case reports or case series that have been published, the ketogenic diet has been added
to existing treatment. So the person is already in counseling. They're already taking one, two,
three, four, five medications. And then you add, and they're not really responding. They're,
they're not getting much relief from those conventional treatments.
You add the ketogenic diet and they improve.
Off they're going, yeah.
And so it's, in fact, there was just a study published.
There were actually several different studies,
but a study was just published out of Oxford University a few weeks ago,
first ever what's called a randomized control trial,
which is a more rigorous kind of clinical trial,
where they took people with so-called treatment-resistant depression,
which just means they have not responded to two,
at least two different antidepressants.
So they took this group of people with treatment-resistant depression.
They divided them into two groups.
And they put one group on a ketogenic diet,
well, 30 grams of carbohydrate per day.
And they put the other group on this diet that they made up called the Fido Diet.
And the Fido Diet.
It was just supposed to be like a placebo, like a sham diet that wasn't supposed to do anything,
but that people who were in the study would believe it would do something.
So they said, oh, you have to eat one extra colorful fruit or vegetable every day,
and you have to replace your cooking fats with olive oil.
And that's going to be really good for your depression.
So the interesting thing about this study, not too surprising,
but interesting is that both groups got a lot better.
both of those got a lot better.
The keto group got even better, but both groups got better.
And if you had very serious severe depression, the keto group got much better than the other group.
So you saw some separation there, but what this really tells us is that, you know, and this happens a lot,
when you enter a study and people are paying attention to what you're eating and you're trying to,
of course, you're going to make a lot of changes and you're going to feel support.
and you're going to get better if you pay attention to your diet and if other people are
supporting you.
So, oh, good combo.
Hopeful.
Hopeful.
Yeah.
Where do you think the GLP ones fit into this?
You know, they've become so popular.
And my take is that I can see the benefits, but I also see all the fasting lifestyle I've
taught people has given a very similar result.
the GLP ones can accomplish. We're seeing hemoglobin A1C come down, and yet we're seeing some statistics
like depression actually goes up because people don't have been using food to help their
depressive symptoms. So how do we fit the GLP1 conversation into this conversation we're having?
Well, yeah, you know, GLP-1s are popular because they work, right? So, and how do they work? They help people eat a lot less. Yeah. That's the problem. So why are we eating so much more than we need? Yeah. Right. So if we need a drug to turn down our appetite, why is that? And are you going to do that for the rest of your life? Are you going to put kids who are overweight and obese on one? I mean, this, we can't medicate our way.
out of this overeating pandemic. Well said. Well, said. Why are we overeating? And so something is wrong.
And it's not because we don't have willpower. It's because the foods we're eating make us
hungrier. They make you hungrier. And so you want to eat foods that are satisfying,
that are real whole foods. We've been doing that for two million years. And suddenly, in the past
50, 75 years, we're not eating food anymore. We're eating factory processed ingredients that start
out as whole foods, but they don't behave like foods in the human body because they've been
concentrated and extracted, powdered and liquefied and crystallized. That's not what we're supposed to be
doing. And they really throw off your appetite regulating mechanisms. Yes. So they make you more,
I think they make you more hungry is really important.
I just did a video on YouTube about that,
and I think it was 600 calories more a day.
Somebody will eat if they are eating an ultra-processed diet
compared to a whole foods diet.
And a lot of people who eat ultra-processed foods diets think they're saving money
because it's cheaper food, but you actually become more hungry
and you're eating more food than if you spent it eating a whole foods diet.
Thank you. That's exactly right. And people always say, oh, I can't afford to eat real food. Well, you can't afford not to eat real food.
Right. Right. Well, we were not even talking about the medical bills you'll have to pay for.
Exactly. The co-pays and the doctor's visits and the surgeries and the hospitalizations and injuries and everything else.
But yes, actually, there was a study of people with Alzheimer's disease where they put half the group on a ketogenic diet and they put the other half a regular, I think it was a little fat diet.
I can't remember what the diet was being compared to.
It was kind of more of a standard diet.
And they said, you know, you can eat as much as you want.
We're not going to limit how many calories you eat,
but just, you know, this group on the ketogenic diet,
and they were just going to look at memory testing, right?
And so the group on the ketogenic diet did a little bit better on the memory testing,
not a lot.
We could talk for a long time about that, a little bit better.
But what was remarkable was the group on the ketogenic diet
without anybody telling them to and without them trying.
They naturally ate 550 fewer calories per day.
Yeah.
Yeah.
The hunger goes away.
The first time the GLPs came out, I was like, I went to people that I knew were on them.
I'm like, tell me what you notice.
And they're like, I'm not hungry.
I'm like, yeah, that's what happened to me when I started fasting.
I was, my hunger went away.
Like we used to have a joke in my clinic when somebody would come in and they'd lost 30 pounds
in a short period time.
And they're like, and I'm not even hungry.
I was like, shh, don't say that too loud.
You might upset some people in here.
So, you know, for me, I think we don't give the body enough credit what it's capable of doing
when you give it the right fuel source.
And we've given gLP ones or all the heroes.
And yes, they've helped and save a lot of lives.
But to your point, what's the exit ramp?
And how can you do this on your own to take your own power back and save your own money?
Right.
The exit ramp, and so there was another study.
Sorry, I'm saying I was a studies.
Yeah, yeah, no, I love your studies.
A study nerd, but another study by Verda Health, and that's a virtual type 2 diabetes
clinic that uses low carbohydrate diets to help people get off diabetes medications and manage
their glucose levels and lose weight.
Verda Health published a study two years ago, I believe it was, where they took people
who had responded nicely to a GLP1, they'd lost weight, they'd gotten their glucose levels
under better control, and then they switched them.
to a low carbohydrate diet and they and took them off the jlp1 and they were able to maintain all of those
benefits even a year later so that's that's a great exit frame and it's not the only one i mean as you
and i have talked about before there are a lot of similar benefits to intermittent fasting compared to
ketogenic diet so whatever works best for you but that's right make sure that you are finding a way
to keep your glucose and insulin levels in a healthy range and to keep your metabolic
metabolic health where it needs to be. And so that, and you're eating in a way that that doesn't make
you hungry. Right. Yeah. So, I mean, that's such a, let's just think about that comment,
eat in a way that doesn't make you hungry. People eat because they're hungry. Right. But,
but I always think, and the way, this is literally the way my brain thinks, when I eat a meal,
I ask myself, how do I want to feel two hours from now?
Right? Like I'm like, I'm not just eating for my taste buds. I'm eating for performance.
Like, how do I want to feel two hours from now? And sometimes I'll dip in, I'm gluten-free,
but sometimes I'll dip into a bowl of gluten-free pasta knowing two hours from I'll be sitting on the couch watching a movie.
I don't really care how I feel. But if it's during a workday, I'm very methodical about what I eat so that I don't get that glucose too high.
Briggs, then you have control. So you understand, if you understand your body,
how it works and how different foods affect you, it doesn't mean you can never have that food again.
That's up to you. Right. It just gives you more control. So now you understand, okay, I want to have
this food, but I know what it's going to do to me, but that's okay. It's a conscious choice I'm making.
Rather than saying yourself, I know this is, I'm supposed to be eating whole wheat muffins every day
because, you know, for fiber. Yeah, because my doctor said so. Right. And which doesn't make any
biological sense whatsoever. So don't fool yourself into thinking that certain things are good for you.
it's okay to eat things that you enjoy from time to time that might not be, it's not about
being perfect.
It's about understanding, working with your biology and having more control.
Yeah, I agree.
I love that.
I think that's really important.
Are there certain groups of people that do better with ketones, their brains do better
with ketones than other groups?
I mean, we talked about chronic depression and schizophrenia and dementia.
but do we have other groups that we know like yeah you should be doing ketones we know the thing is
that ketones at least being intermittently in ketosis we know that that's good for the brain full stop right
yeah so the brain needs needs to my reading of the science is the brain needs to go in and out of
ketosis it needs to spend at least some time in ketosis on a regular basis so i think it's good for
no matter what the condition is but the question you're asking is really interesting because
there are, like we were saying before,
some people just need to clean up their diets,
some people just need to get their glucose levels under control,
some people just need to eat less, whatever it is.
All those things can help support better brain health,
but who are the people who need those ketones?
Right.
And especially who need them in a really good range.
And we're starting to get a better feel for this.
But the short answers we don't know,
But I think a better answer is the people who are going to do best with those ketones are the people whose brains have lost some of their ability to use glucose for energy to full capacity.
Yes.
So if you've lost some of that metabolic flexibility and you've burnt out some of your glucose pathways by overusing them and you've made your brain insulin resistant by bombarding your brain with too much insulin too many times.
over too many years, the brain becomes insulin resistant, becomes harder and harder for insulin
to get into the brain.
Glucose can still walt in, no questions asked, but now you don't have enough insulin
because you're insulin resistant.
You know, your brain can be swimming in a sea of glucose and still starving because of
lack of insulin.
So people who have lost some of their glucose processing capacity, they really need ketones
because there is no other molecule that's going to be able to bridge that energy.
gap. If your brain is having trouble burning glucose, more glucose is just going to make the problem
worse. Right. You need key. Tones are your only hope. We'll be on Canobe. I love that. I am like,
amen, sister. I, you know, so I just, since we last talked, I published another book called
Age Like a Girl. And it's all about. When you have time to do this? I know. Well, I'm on a hiatus from
book writing for a while. I'll send you a copy of it.
this one. And I have a whole chapter on fueling the menopausal brain. And in all the research I've
seen that we see this as estrogen goes down, I would put menopausal women in the category that
you just said. The menopausal brain cannot use glucose as efficiently as it used to.
And then I paired that, I paired that thought with, I was actually on a podcast back in January
with a neurosurgeon.
And she says to me, did you know that when a woman's brain goes through menopause and those neurons
start to prune away, the old neurons, because there is a pruning process, these neurons get
pruned away, making room for new neurons to form, the degeneration of the neuron in the
menopausal brain, the byproduct of that is a ketone.
the brain and I've been dying to ask you this because basically she's saying that the brain knows
it's rewiring itself it knows it's getting rid of these neurons it no longer needs many of them
are those inside the hippocampus some of them are in the amygdala areas that were that kept as
addicted to people pleasing and performative mode we get this
it's pruning away and the brain is so intelligent that it knows that there's a shift happening
that is going to require the fuel source of a ketone. Well, what I haven't looked at that.
So I've written it down because I'm, yeah, I'll send you the study. Thank you. So, but, but what I can tell
you, which lines up perfectly with what you were just saying is that when you were in ketosis,
remember we were talking before about how the brain enters a healing mode, where you're recently,
recycling and regenerating and cleaning up and maintaining and that sort of thing.
One of the things that happens in ketosis is levels of a growth factor in the brain called BDNF or brain-derived
neurotrophic factor. It's kind of like fertilizer for the brain and it helps you sprout those new
connections and create those new circuits. And so that's what's responsible for something called
neuroplasticity, where the brain is rewiring itself and remodeling itself. If you're not in ketosis
on regular basis, your BDNF levels will be lower. And so if you want your brain to be able to
remodel itself and rewire itself and heal from injury and create new connections, which is
essential for learning and memory, the way you learn or memorize something is you have to
create a new circuit that understands what that new word was or that new skill was. So that
requires building a new little circuit. And you can't do that unless you've got A, some insulin,
in coming into the brain, so you can't be doing insulin resistant.
Right, right.
You've got to have, you've got to spend some time in ketosis
to get the brain-derived neurotrophic factor up.
Because that, those new, sprouting those new connections
requires BDNF.
So lots of reasons why it's good for everybody being ketosis from time to time,
but especially, you know, the perimenopause and post.
menopause, one of the major things that happens for women, and I'm sure this is a major focus of your book,
is that, you know, we become more insulin resistant.
Yeah.
And, you know, the shape of our bodies change, our metabolism changes, and we catch up to men.
Men who tend to gain weight around their midsection, even when they're younger, women tend to gain
in their hips and thighs, but then when they go through menopause, everything changes.
So women become more insulin resistant as estrogen falls away.
And so that is a major challenge for a lot of women to maintain their metabolic health.
Yeah.
I was just curious, do we have any research showing waste circumference?
Because that seems to be for both men and women as they age.
That seems to be where fat accumulates more easily.
do we have waist circumference and cognition or dementia?
Do we have, have we seen any studies that are showing the bigger your waist,
the more cognitive decline is happening?
I want a great question.
I'm going to say, I don't know, but I bet we do, but I don't have my fingertips.
I'm going to look it up, but that's a great question because I bet there is.
I know that there is for glucose levels, but I don't know if there is for waist
circumference in particular, but I wouldn't be surprised. Because I'm thinking it's visceral fat,
and it's the out-expression of metabolic dysfunction. So if you want to know if your brain is
suffering from metabolic dysfunction, my intuitive sense would be look at your waist circumference.
You know, what are we seeing there? Yeah, I mean, waist circumference is a really good marker of
insulin resistance. It's not perfect, but it's very, very good. I mean, there's no one perfect
marker for insulin resistance, but waste to height ratio. So if your waist is more than half your
height, then that, then you're very likely to have insulin resistance. And often that has to do
with visceral fat, the fat around the organs and fat in the liver. And, you know, I think what a lot of
people don't realize, again, is if you're eating too much carbohydrate for more than you need,
more than your personal metabolism can handle, and that's going to be a different level for every person,
then every single extra molecule of carbohydrate that you eat that you can't burn or store right away,
your body turns into your liver turns it into saturated fat.
Right.
Right there on the spot because it has to be else to put it.
Right.
There's no else to put it.
So it's just doing the best it can with a difficult situation.
So you really want to make sure that you're not.
not eating more than you need. And again, it doesn't mean that everybody needs to be on a ketogenic diet.
It just means that what it means, most people are eating so much more than they can handle and
process that, of course, where else is it going to go? It has to go somewhere. Right. Well, how do we
support the communities that either are like a lot of women that follow this podcast, have aging
parents with Alzheimer's and also may have grandchildren who have, you know, ADHD.
And I look at those two groups of people and sometimes it can look impossible to put them on a low
carb diet or to even have them intermittent fast. Did your group look at all at the possibility
of exogenous ketones or how we help those two populations that might really struggle to get
on to a ketogenic diet?
Yes, so there have been a number of studies in Alzheimer's disease and mild cognitive impairment,
so mild cognitive impairment for people out there who don't know that's, you can think of it
as kind of pre-dementia, the way pre-diabetes and diabetes, you know.
So mild cognitive impairment, about 10% of those people every year will go on to develop
an Alzheimer's disease diagnosis, or dementia diagnosis.
And so they've done studies of ketogenic diets in both of those types.
types of situations, and they've also done studies of exogenous ketones and MCT oil in those
situations. And so we still don't have a large randomized control trial, and I believe one is in the
works for the ketogenic diet. But we still don't have a well-conducted large randomized control
trial, which would be wonderful in this population. But the studies we do have, they show promise,
meaning that, you know, there are lots of people in that situation, as you said, who,
let's say they're in assisted living or they're in a nursing facility and they can't change their
diet or they have enough memory challenges that they can't learn a new diet or can't stick to a new diet.
So, and I've had patients in these situations, in those cases where the person either can't
or chooses not to follow a ketogenic diet, exogenous key,
Cetones and MCT oil are going to be your best bet because they can raise ketone levels even if
you're eating a high carbohydrate diet. So it's better than, you know, it's not, it's not perfect,
but it's better because those ketones, the brain is still going to appreciate those ketones,
even though your glucose levels are still too high and your insulin levels are still too high
because you're eating their own foods, your brain will be getting some ketones and those ketones can
energize, help support better brain energy, and can, you can see this in the studies, can
support some degree of improvement in cognition and mental clarity. Yeah, and that's what we used to
do in my practice. A lot of people would ask about, well, what about my mom? You know, she's in first
stage of Alzheimer's, and we would try exogenous ketones. And, you know, this was like 10 years ago.
So it was like there wasn't a lot out there about it. And you would see some brightness.
come back. And I think it's an interesting approach. I was even thinking as you were talking about
like TBIs, people who have had concussions. If the brain is definitely searching for energy,
and it feels like ketone would be really helpful. Yeah, there's some early research on that,
too, that the ketogenic diet has tremendous potential for traumatic brain injury. Again, because
when you're in ketosis, you enter healing mode. And that's what you need. If you've had an injury,
You want your brain to heal.
And so, yeah, and I'm actually working right now with a patient who had a concussion from a car accident in August.
And so I'm excited to see what made possible for him.
It always makes sense.
It always makes sense to consider a ketogenic diet no matter what the brain condition is.
It doesn't mean it's always going to be the right thing to do or the safe thing to do or even the feasible thing to do.
but it's always the right thing to consider.
And that's where our consensus, expert consensus,
comes in because there are situations where you don't necessarily want to just jump right to a ketogenic diet.
And there are many situations where you're going to need some extra knowledge and skill
in order to be able to do that safely.
Yeah.
Why do you think the ketogenic diet was dismissed is what I'm going to say?
I've been teaching ketogenic diet to my patients for 15, 20 years.
It's got its roots in epilepsy.
I mean, there's so much good research.
But it seems to me as it became more of a fad, just like every nutritional strategy,
is everybody's all excited about it and then people start criticizing it.
Why do you think people went after the ketogenic diet?
Oh, my gosh.
Well, lots of reasons.
I mean, first of all, there's a lot of confusion and misunderstanding about what a ketogenic diet is.
I mean, and like any diet, there are healthy ways to do it and not healthy ways to do it.
Same thing with fasting.
I mean, any nutritional approach can be done well or less well.
And so, you know, you can eat a ketogenic diet where all you're eating is keto junk foods all day long.
Very true.
And you're overeating all day long and you're never giving your body a break and you're eating all the wrong foods and you're eating too many calories and you're eating all the,
So that's not the right way to do it.
There are other versions of ketogenic diet, especially the original version, which 1921,
we think of the ketogenic diet as a weight loss diet.
But as you were saying, it's originally designed over 100 years ago to stabilize brain chemistry
in children with severe epilepsy, which it actually is extremely helpful in those cases.
So what better, you know, what better evidence,
you need that the ketogenic diet can stabilize brain chemistry, then stopping seizures. And so,
yeah, it's the ketogenic diet, the original version of it, was very strict and extreme.
Yeah, it was like, it was like 10 grams of net carbs. It was almost Atkins. It was like,
just, just eat meat. It was, well, unfortunately, no, the original version of it. Oh, the original
original. We're talking way back 1921. The original version was designed to get as close to fasting as
possible while still providing some nutrition for these children because all they knew at that time was that
fasting helped with seizures. But you can't fast forever. And so what do you do? So what do you feed the child?
And so what this was was a diet that was designed to get ketones into a very high range,
five to eight millymol per liter, very high, and keep them there for you.
a year or two. Oh, wow. And I know. And so it required not just bringing carbohydrates down to about
four or five percent of calories. It required minimizing protein, bringing protein down to a lot.
I want to say, I think it was about six percent of calories, far too low.
Too low for sure. So it just wasn't nutritious enough. It wasn't enough protein to support growth
and reproductive pathways. So you saw side effects. And so again, that,
So there's criticism of the ketogenic diet is often rooted in some of those older studies where the diet was very extreme and not nutritionally complete.
And so part of this has to do with misunderstandings of the definition and how best to do it and what the right way is to do a ketogenic diet.
But I think another source of criticism about the ketogenic diet is that it's often misunderstood.
Well, you have to eat red meat and you have to eat dairy.
No, you don't.
Nope.
Nutiosis is not about plants and animals.
You can have a vegan ketogenic diet.
You can have a heart of a ketogenic diet.
It's not about the plants and animals.
And a lot of people have strong reactions to diets that include animal foods.
And so there's that backlash.
The third backlash is people love carbohydrates.
And so they're like, let's make that bad.
Right?
Like, oh, that can't be good for you.
So there's an emotional reaction to it's like, oh, really, I can't imagine living without these things.
Really, I can't ever have these things again.
And so I think there's a lot going on there.
Yeah.
And that's why I actually switched over the years of talking about ketosis more from a fasting lens.
Because I look at a 24-hour cycle and I'm like, you have a fasting window and you have an eating window.
When you switch into that eating window, you get to decide what you're going to eat.
if you want to stay in ketosis, then you're going to need to look at keeping that carb count down.
So, but for that exact reason is that the confusion, the blame.
And I was like, okay, let's just stop talking about the diet and let's talk about how you can
use fasting to get into ketosis.
And I found that people were more receptive once I did that.
Oh, yeah.
I mean, so you have to know who you are.
So some people are all or nothing people.
Right.
And they, it really helps to have those black and white.
white lines, okay, I'm going to not eat during this window, and then I'm going to eat what
I enjoy during this window, and that's how I'm going to manage my metabolic health. That's how I'm
going to get healthier. There are other people who, and I would count myself in this group,
I can't go back and forth because it's too triggering for me to be able to include some carbohydrates.
I'm too addicted to them, and it becomes difficult for me to stay in that lane. And so
for me, I know myself, because I've tried it many times, it's just too hard for me.
And I feel better when I just kind of stay in ketosis.
But I think that, you know, there are different ways to get into ketosis.
Fasting get you into ketosis.
Intense exercise can get you into ketosis.
Well said.
Calorie restriction get you into ketosis.
And a ketogenic diet and get you into ketosis.
And so, you know, choose the methods that work best for you.
But however you can get there, make sure you spend some time there because that's, I really think,
it's going to be the key for most people, as you say, to kind of unlocking their own good health.
Like we all have access to this.
We just find the best way that works for us to get.
Our rhythm.
Yeah.
How is the mental health community taking this good news of the ketogenic diet?
ketosis. I'm assuming this consensus, expert consensus was important, probably in a large way to your
own community to say this is what we are finding as protocols. But do you think we're still years
away from the mental health world, psychologists, behaviorists, psychiatrists, really accepting
this diet as treatment? I think we're probably two to five years away from that. And the reason I say
that is because it's already changing. Every time the study comes out, more and more people hear
about it. And there are studies being done around the world at some most prestigious institutions.
Harvard, Stanford, the University of Edinburgh and Scotland, James Cook University in Australia,
Leiden University in the Netherlands, I mean, I could go on and on and on. Oxford. I mean,
this is a reputable field of academic exploration where we're seeing really promising results
in conditions which where a lot of people have lost hope.
Right, right.
The treatments we currently have,
it's not that they don't help anybody.
It's that they do unfortunately,
they're extremely limited in what they can do for people
and they come with tremendous side effects
and they unfortunately fall short for most people.
Yeah.
So we need another way forward.
And so I think there is,
Every time a study comes out, it kind of chips away at that either lack of awareness or that
resistance or the worry about these diets from mental health. And so I think, and as the next
study that's going to come out is going to come from James Cook University in Australia is going
to be 100 patient, very, very carefully conducted randomized controlled trial of ketogenic diets
in bipolar disorder and schizophrenia.
Yeah.
Conducted by very careful, reputable researchers.
Amazing.
I'm very curious to see what the response will be to that study when it comes out.
And so, I mean, in a very short period of time, I think that any clinician in the mental health space who does not know about ketogenic diets and is not able to talk intelligently with their patients about them is going to be left behind.
Yeah.
Yeah.
And, you know, there's, I've watched nutrition trends my whole life. I've been fascinated with nutrition
since I was a young girl. I actually went to the Pridicin diet and did the whole Pritken diet.
Yeah, when I was 16 years old, I'm like, just because I wanted to understand, I just love how diet makes
us feel. And you see diets come and go and you see some stand this test at time and this one's
standing the test at time. And yes, it's had some arrows. Ketogenic diet has had some air.
at it. But I think the way you describe that is that we're going to start to see more and more people
come back to it and find their own rhythm with it because this is not prescriptive of keep your
carbs at 10 grams. This is, like you said, it could be fasting, it could be exercise, it could be
plant-based, it could be carnivore. And I think that's so important, the flexibility of it.
Oh, yeah. I mean, you know, I'd like to say I'm nutritionally pro-choice.
You know, that's good.
So, you know, whatever diet you feel most comfortable,
whatever dietary pattern you feel most comfortable with,
as long as it doesn't involve like Twinkies and Oreos and things like that.
That's right.
There's a way for, you know, there's a way for you to design a ketogenic diet
to suit your dietary preferences.
And so everyone can access the healing benefits of ketosis,
regardless of their dietary preferences.
And the reason why we published,
this expert consensus, what was, I mean, partly for clinicians who around the world who
they have their patients coming to them and saying, I've heard ketogenic diet might help me
with my depression or my ADHD or my bipolar disorder or whatever it is, can you, can you,
can you work on this diet with me? And they may not have any experience or knowledge yet about it.
So we said, okay, this, here is how you would approach that situation. Here are the lab tests you
would get. Here are the things you're going to think about. These are the people who are going to
be good candidates. Here are the people who need extra monitoring. This is, this is what you're,
this is what you're going to be looking for, and this is how long you should try it. And this is
all kind of those just practical information for clinicians, but also for patients. So patients,
who go to their psychiatrist or their therapist or their primary care and say, I want to do
a ketogenic diet for mental health, and they look at you like they've never,
heard of this. And they can bring this paper, it's an open access paper, bring this paper,
it's free, and, you know, and hand it to them and say, would you be willing to learn more about
this and help me with this? Because there are many situations where you're not going to want
to start a ketogenic diet on your own without professional support, especially if you are taking
any kind of prescription medication or if you have any kind of medical health issue, a high blood
pressure, cardiac disease, type 2 diabetes, I mean all kinds of situations where the medicines
and your health condition is going to need to be carefully monitored. Because this is a powerful
intervention, which is of course exactly what you want. But you want it to be safe and comfortable.
in that first couple of weeks, you kind of have to navigate the rocky shores of the diet first.
Just you can get to that other side in that better state of mind that you're looking for.
It reminds me of the New England Journal of Medicine did something very similar with fasting
about six years ago where it was in a meta-analysis.
They actually went in and looked at several different studies and came out with a prescriptive plan
that was like these are the five conditions, neurodegeneration was one of them, that you should
consider intermittent fasting for. And they even have, if you go and look at the study, they have
protocols. They show like, do this week one, week two. And it really was a breakthrough in the fasting
community because now doctors were not looking at this as like a fad. They were looking at it
prescriptive like you were talking about. And I'm thinking, wow, now we have two really powerful
combination, that New England Journal of Medicine, which will leave the link to that and your
expert consensus. We'll leave links to both of those. And I love your suggestion of take that,
take that to your doctor and say, can we talk about this? I just think what you did is going to
accelerate doctors' willingness to take this in as therapy. I hope so. Because
because it's a really powerful tool that you can add to existing care.
That's right.
You don't have to pull the baby out with the pathwater.
Yeah.
So if the therapy is working, if the medicines are partly helpful,
it's not about either or or, you know, this is better than that.
It's about another tool in the toolbox and a really powerful one.
And so, you know, I think it's really, I think there are a lot of clinicians out there
who are curious about it, but they just don't have the experience or the, or the information they
need to be able to feel confident in supporting their patients. So that's why we published this
document is to support clinicians and patients around the world who want to explore the potential
of this really powerful metabolic intervention. You're like, like I've got a kindred ketone sister
here. Yeah. I really, because I've watched from a different lens,
I've watched millions of people heal themselves with fasting, and it hasn't been all weight loss.
I mean, it's a combination.
And brain health is a big piece of people's result.
Well, you know, there's nothing wrong with wanting to lose weight, right?
Of course.
Who is overweight that doesn't want to lose weight, right?
Right.
And the wonderful thing is that you get these wonderful side effects, side benefits.
So yeah, you're going to lose some weight.
That's great.
And guess what else?
your mental health is going to improve.
Other aspects of your physical health is going to improve.
All these side benefits.
And so all kinds of things are going to get better.
And hey, you're going to look better and feel better too.
So, you know, what's not to love?
It works so well.
I always say when I tell people they're like, oh, I'm interested in fasting.
I always say, yeah, if you want to come for the weight loss, that's great.
But stay for the rest of the results.
Don't leave after the weight loss because there's so many incredible results.
So many things to look worried to. And that people can access, like you said, is if you trust your body
and you give it what it needs, it will respond. Yeah. Yeah. You can, it will. It knows,
it knows how to heal itself if you get out of its way. Oh, it's so true. It's so true. Well, Georgia,
I love talking to you. How do people find you? I know, I mean, you've got the book,
change your diet, change your mind. What else are you up to? And if people want to dive into
your work, where can they find you? Yeah. So I have a website, which
is a diagnosis diet. That's the name of my website. You can find information about the book there,
but you can also find all kinds of writing there. And I teach a course, a CME accredited course for
clinicians and ketogenic diets for mental health. And so that's between the course and the book
and writings and conferences. I'm going to speaking at a couple of conferences coming up. I don't
know when this episode airs. In Italy, at the end of April and in London at the end of April,
speaking out a couple of metabolic health conferences because the book is coming out in Italian
which is really exciting yeah that's so fun it's fun for me but so there be a conference in Italy
where where the book will be coming out at that same time and then an integrative health conference
in London I'm just convinced on the power of ketones more than ever and when I saw the new
consensus come out I was like we got to bring this back to the surface great I really I
I really appreciate it. Thank you. I hope it's helpful to people. Yeah, thank you. Appreciate you.
Thank you, you too. Bye, Mindy.
Bye.
Thank you so much for joining me in today's episode. I love bringing thoughtful discussions about all things health to you.
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