The School of Greatness - The Nutrition Doctor: “THESE Foods Can HEAL - REVERSE DISEASE & AGING!” (It’s SO SIMPLE!) Dr. Michael Greger

Episode Date: March 4, 2024

Today on The School of Greatness, we welcome Dr. Michael Greger. He's not just a physician and a New York Times best-selling author but also an internationally recognized speaker on critical public he...alth issues. His extensive research, especially in the realm of industrialized animal agriculture and its public health implications, is groundbreaking. Dr. Greger's dedication to clinical nutrition has established him as a leading authority in the field. He's the author of several best-selling books, including "How Not to Die" and "How Not to Diet," which have revolutionized the way we think about food and health. His work at NutritionFacts.org is not just informative but transformative, impacting lives globally. Today, Dr. Greger joins us to share his invaluable insights on nutrition, public health, and how we can all lead a healthier, more fulfilling life. Buy his book, How Not to Age: The Scientific Approach to Getting Healthier as You Get OlderIn this episode you will learnHow changing your diet can potentially stop or even reverse aging.The significance of fasting and the optimal time to stop eating daily for longevity.The top five anti-aging foods and the best nuts and whole grains for a healthy life.The impact of circadian rhythms on life optimization and the ideal daily diet for longevity.Strategies for losing fat effectively, the difference between bad cells and zombie cells, and the hidden health benefits of foods like red onions.For more information go to www.lewishowes.com/1583For more Greatness text PODCAST to +1 (614) 350-3960More SOG episodes on HEALTH & WELLNESS we think you’ll love:Glucose Goddess – https://link.chtbl.com/1575-podDr. Mark Hyman – https://link.chtbl.com/1560-podDr. Mindy Pelz – https://link.chtbl.com/1543-pod

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Starting point is 00:00:00 Welcome to the School of Greatness. My name is Lewis Howes, former pro-athlete turned lifestyle entrepreneur. And each week we bring you an inspiring person or message to help you discover how to unlock your inner greatness. Thanks for spending some time with me today. Now let the class begin. with me today. Now let the class begin. Welcome back everyone to the School of Greatness. Very excited about our guests. We have the inspiring Dr. Michael Greger in the house. Good to see you sir. So glad to be here. Welcome. This is exciting. This is exciting. Your research has been really out there in the mainstream a lot lately. A lot of documentaries, your books have been blowing up. And the most recent one, How Not to Age, the scientific approach to getting healthier as you get older.
Starting point is 00:00:55 I'm really fascinated by it because most people don't think they can actually get and improve their health the older they get. They just feel like they have to deal with chronic pain, illness, disease. They have to take medications to just maintain a level of ease. So is it actually possible to stop aging or even reverse aging with foods as we get older? Dying appears to be the most critical element. And that's really what the book is about, this kind of good news that we have tremendous power over our health destiny and longevity. The vast majority of premature death and disability is preventable with a healthy enough diet and lifestyle. Really?
Starting point is 00:01:36 Only about 25%. Based on studies of identical twins, only about 25% of the difference in lifespan between people is due to genetics. Really? So for what we can do over the majority of which we have some control, we can look to, for example, these blue zones, these areas around the world with exceptional longevity, and kind of look at the Venn diagram and what they're all doing. According to the Global Burden of Disease Study, the largest systemic analysis of risk factors in history, the number one cause of death in these United States
Starting point is 00:02:06 is the American diet. Really? Bumping tobacco, smoking to number two, cigarettes not only kill about a half million Americans every year worse, our diet kills many more. Come on. So, but that's good news, because that means we have the power, right?
Starting point is 00:02:22 It's never too late to start eating healthier, to stop smoking, to start moving. So, I mean, it's really a positive message that I was excited to learn when I finished the book. So when we change our lifestyle, when we change our eating habits and our nutritional habits, we can actually reverse our aging or age better is what I'm hearing you say. We can age slower. Age slower. Age slower. And because aging is a significant risk factor for most of our leading killers, you know, so my first book in the series, How Not to Die, was, you know, first half of the book is just 15 chapters, each of the 15 leading cause of death.
Starting point is 00:03:00 Talking about the role diet may play in preventing, arresting, reversing each of our top 15 killers. Wait a second. I mean, if, I mean, death is from disease, arresting, reversing each of our top 15 killers. Say, wait a second. I mean, if death is from disease, why isn't how not to die kind of all the longevity book anybody needs? That's because aging is a risk factor for multiple different diseases. So, for example, if all cancer were cured tomorrow, it would only add about three years to the average lifespan. Really? Wait a second. Why is that?
Starting point is 00:03:24 It's like our second leading killer. It's because if you don't die of one age-related disease, you'll just die of another one. So the only reason you didn't die of a heart attack, ah, because you died of cancer the month before, but you were going to die anyway from something else. So by slowing down the aging process, then we can reduce the risk of many different diseases
Starting point is 00:03:42 at the same time, the stroke and the dementia and cancer, heart disease, which rise exponentially with age. Really? So something like having a high cholesterol can increase your odds of having a heart attack, our number one killer of men and women, by as much as 20-fold.
Starting point is 00:03:57 But an 80-year-old has 500 times the risk of having a heart attack compared to a 20-year-old. So age, but I mean, of course, the reason we focus on things like cholesterol is because it's a modifiable risk factor. But what if the rate of aging were modifiable too? And so that's what I really like covering the book. So what would the five main keys be to aging better? Yeah, so diet, number one.
Starting point is 00:04:24 And so if you look at these blue zones, they all center their diets around whole plant foods. So they're minimizing the intake of meat, dairy, sugar, eggs, junk, maximizing the intake of fruits, vegetables, legumes, beans, split peas, chickpeas, lentils, nuts and seeds, herbs and spices, basically real food that grows out of the ground. These are really our healthiest choices. That would be number one.
Starting point is 00:04:48 Number one, diet. So number one, diet. So that accounts alone for about half of the difference in lifespan between blue zones and the rest of the world. What is the average blue zone age at death versus the average age of death of non-blue zones. Right. It's about 12 to 14 years. 12 to 14 years difference.
Starting point is 00:05:09 Difference. So women 14, men 12 years longer. And so have up to 10 times the rate of so-called centenarians, those that get triple digits, live to be 100 or older. And it's not just about, you know, adding years to your life, but life to your years. These people are active. So they're at 100 and they're enjoying their lives or participating in life. And so what's the point of living longer if you can't do it, you know, with vibrancy, with vitality, right?
Starting point is 00:05:36 And so in this country, I mean, even our lifespan is going down. So actually the peak of life expectancy, 2014 in the United States, started going down every year since, even before COVID shaved a few years off our lifespan. Now there's certain pockets that are blue zone pockets. Right. But in general, and it's because primarily the obesity epidemic. So we are raising the first generation of Americans set to live shorter average lives than their parents, right? And this was before COVID. It continues to drop down. We are 39th in life expectancy around the world. So like Slovenians live longer than Americans. So we've got a lot of work to do, but the good news is, again, we have power over how we live and what we eat.
Starting point is 00:06:24 So diet would be the main thing. What would be the second or third thing, would you think? Okay. And so then smoking cessation, critically important. Now, so what else? Smoking versus vaping. Ah, well, the concern, the primary concern about vaping is the nicotine addiction will lead people to smoke.
Starting point is 00:06:42 And so it's safer than smoking, but because people who vape tend to smoke that unfortunately, you know, these kids getting addicted to nicotine can face a lifetime of cigarette addiction and then dramatically cut their life short from something like lung cancer. So smoking. So, so yeah. So it's really remarkably, you know, 80% of not smoking, not being obese, exercising, even like 20 minutes a day, five servings of fruits and vegetables, really basic stuff. Now, you want to go beyond that? You want to tweak those 20%? I've got hundreds of cool things you can do with a book.
Starting point is 00:07:37 But let's not lose sight of the real core tenets. So you can imagine some smoker who was like, oh, look at this fancy supplement I'm going to take. I'm like, no, no, no. Let's back up. It's not going to minimize the smoking. Right, right. So, I mean, that's important to emphasize. In fact, the conclusion of the book, I'm like, all right, let's step back. Let's put this all in context again. It's really the core, basic tenets. And then, yeah, there's all sorts of cool new science out there that you can tweak around the edges, but I don't want people to get lost, really.
Starting point is 00:08:12 Okay. And what about fasting? Because you mentioned fasting briefly, and I know you have a section in the book about intermittent fasting and fasting. But also, I think there was a quote in your book that's, you know, fasting can have benefits, but if you fast too long, you die. Right. It is the ultimate in unsustainable diet. Right. Meaning guaranteed to kill you if you do it long enough. Like what?
Starting point is 00:08:34 You can't say that about any diet. But so there's all sorts of interesting intermittent fasting regimens. So one thing that fasting does is it boosts something called autophagy, which is kind of this house cleaning process within the cells. Killing the zombie cells, right? Oh, that's a separate, that's cellulose senescence. That's a whole separate thing, but this is more inside the cell, the accumulation of debris that contributes to the aging process. And we can boost autophagy with exercise or with fasting. We can fast or go fast. Unfortunately, it doesn't really ramp up until 36 to 48 hours of fasting,
Starting point is 00:09:11 which really is too long to go unsupervised. Normally, your kidneys dive into something called sodium conservation mode, such that people can fast literally for months on water only. But if that response breaks down, then you can suffer a serious electrolyte abnormality, which only manifests with vague symptoms like dizziness or fatigue that could go unnoticed until it's too late. Really?
Starting point is 00:09:39 So that's why one really should only fast, if you're fasting over a day, it really should be done under medical supervision. They can do urine tests, they can do blood tests, just to make sure everything's going to plan. Otherwise, you can run into really serious stress. Do you feel like doing a 24-hour fast is okay for people to do on their own? So, although we're not going to get that boost and not toughening that short of a time, and you often hear, like, even a few hours, like, time-restricted feeding, you know, decreasing the feed in window daily, we can improve autophagy. That's in rodents.
Starting point is 00:10:11 Unfortunately, rodents have these really high metabolisms such that they can lose massive amounts of their body weight in literally a day or two, and a few days it can be fatal. But unfortunately, that doesn't translate into humans. Really? We really only get this boosting in our topsy. Really, yeah, two days. And then we're concerned about that being done outside of kind of medical supervision. Is there benefit to doing the intermittent fasting, would you say?
Starting point is 00:10:35 Okay, but there is some, certainly, there's so many different types. I'm talking about the pros and cons of each. So there's alternate day fasting and 5-2 fasting, 25-5 fasting, mimicking guys. Mimic fasting, yeah, yeah. Right, all sorts of it. And there's pros day fasting and 5-2 fasting, 25-5 fasting, mimicking guys. Mimic fasting, yeah, yeah. Right. All sorts of it. And there's frozen cons of each. I think the best, kind of the bottom line, the best evidence is around early time-restricted feeding,
Starting point is 00:10:54 meaning collapsing one's daily feeding window to at least 12 hours or less, but critically important, that window is early rather than late. So if anything anything we're skipping supper not breakfast in fact we're trying to cram as many calories earlier in the day as possible the exact same food eaten in the morning is less baddening than the exact same food same number of calories eaten in the evening come on causes less of a blood sugar spike causes less triglyceride if you're gonna eat junk right if you're gonna eat a donut or something, do it in the morning. Actually,
Starting point is 00:11:27 your body, because of our circadian rhythms, is better able to handle it. Ideally, we should not be eating when it's dark, should not be eating after 7 p.m. Our bodies just have these exaggerated responses to it, or in the very least, we should be eating really healthy food. And so, really, so ideally, breakfast or lunch would be the biggest meal of the day and may actually help explain the longevity of the final remaining blue zone today. There's only one left. We think of these blue zones.
Starting point is 00:11:54 These are historical things. These are six or seven zones, right? Right, but these are historic blue zones. Now they're eating KFC like anybody else. Right. But there's one left, and it's the red, white, and blue zone. It's the only one.
Starting point is 00:12:07 It's Loma Linda, California. An hour away. The seven-day Adventist. And one of the things that may be attributing to their longevity, in fact, they're the longest formerly studied population, longest living in history, living longer than the Okinawan Japanese, even during the 50s when they were at the peak. The Sardinians, all of them.
Starting point is 00:12:25 They beat them all, and they're the only ones continuing to go. And one of the things they may be doing is because they tend to eat lunch as their biggest meal of the day. So they don't have a big dinner. So they don't have a big dinner. Or they skip dinner all entirely.
Starting point is 00:12:42 I mean, they have lots of other things going for them. Maybe here and there, but not... Right, so their body is, they consider their body a temple, it's kind of a biblical teaching, and so they really, so they have low smoking rates, they exercise,
Starting point is 00:12:52 tend to have plant-based diets, so they're doing a lot of things right. Immunity, all the things, yeah. Right, but that may actually be one of the factors, even though it's never been kind of put to the test in an interventional trial. Based on the studies, they're not eating a lot of dinners is what I'm hearing you say.
Starting point is 00:13:11 They're eating either light dinners or they're not eating dinner at all. Or they're doing it before 7 or 4. Before 4, before 4, yeah. What would be the optimal time to stop eating every single day? Well, so before 7. We want to get before 7. every single day. Well, so before seven. We want to get before seven. And so that's what, I mean, the intermittent fasting literature around time-restricted
Starting point is 00:13:28 feeding was so confusing because some studies show it's actually bad for you, cause metabolic issues. Others found it had these remarkable benefits, and it's all in the timing of the window. The ones that were late-restricting, skipping breakfast, and not eating till late, then they had actually problems associated. And you know, it's in that higher cholesterol at the end of a few weeks. Because if you're skipping breakfast and you're, say, you're eating at one or two o'clock, but then you're like, you're hungry, and so you're eating more later in the evening until
Starting point is 00:13:58 nine, 10 o'clock maybe. That's exactly the opposite that we want to be doing. But you're still getting that maybe 16 hour window of not eating. Right. But you're saying that the time you eat is more important than how much time you don't eat. There's benefits to both. Yes. So you can.
Starting point is 00:14:13 So just by time restricted feeding. So even if you do it kind of in the middle, there's benefits from not time restricting. But there's additional benefits. Switching to skipping dinner. Yeah. Yeah. And that was actually the U.S. military did these experiments. from not time restricting, but there's additional benefits switching to a really- Skipping dinner. Yeah, yeah. And that was actually the U.S. military did these experiments.
Starting point is 00:14:28 The Army did the first experiments where they actually took people and gave people 2,000 calorie meals, a single 2,000 calorie meal, the exact same meal, either as breakfast and fasting the rest of the day or as supper.
Starting point is 00:14:41 And they found these remarkable differences. The exact same food, exact same calories, different amount of body fat, different amount of metabolic implications of just that single tweak. It's because of chronobiology, the remarkable impact that our circadian rhythms have on our biology.
Starting point is 00:14:56 We typically only think of our circadian rhythms when we're jet lagged. That's the only time we're even thinking about our bodies. But that's just kind of a symptom of this really deep underlying. Most of our biological processes, our biochemistry, our enzymes actually go on this clock. And so it really matters. There's this really devastating literature about pesticide suicides. In India, that's a common way for people to commit suicide. But it matters whether they survive, whether they do it in the morning or in the evening,
Starting point is 00:15:32 because their body's better able to handle it in the morning, better able to detoxify. Because of our circadian rhythms, you're much more likely to survive a poisoning attempt in the evening. And this is just how powerful, it just suggests the power of our circadian rhythms. Really fascinating. I dive deep in that in my How Not to Diet book where I was talking about weight loss and that entire field, fascinating. Never learned about it in medical school. Wow.
Starting point is 00:15:58 Now, for those that don't know, what is the circadian rhythm and what do we need to know about it to optimize our life? Yeah. So our circadian rhythm is the kind of daily rhythm, almost 24-hour rhythm. So even if you're put in a bunker with constant lighting, your body will still, you'll have this cycle as if you were, even though you have no cues from the outside, you have no watch, you have no idea what time it is, you'll start getting sleepy at kind of the outside, you have no watch, you have no idea what time it is, you'll start getting sleepy at kind of the same time you normally get sleepy. You wake up about the same time you normally sleep. But in that kind of environment,
Starting point is 00:16:33 you can do these laboratory experiments on people where it's like, okay, what if we put you on a 27-hour cycle? So we put the lights on, right? But then we just stretch it a little bit, and it totally messes people up. Wow. It really undercuts our biology. We were so meant because then all of a sudden it's chopping it through. And so it was these kinds of experiments that really show the power. And so what we see is
Starting point is 00:16:56 we see these shift workers. So people- Or working late nights. Right. So, well, if you're only working late nights, that's a problem in and of itself, but it's the people that are shifting. So they're doing the late nights. So like, you know, people in postgraduate medical ed training, these residents who will do nights in the hospital and then they'll do a day. And that is really difficult. And so. Like a double shift.
Starting point is 00:17:18 Double shift. So there could be many reasons why people that do that kind of work live significantly shortened lives. I mean, there's, you know, who is forced into those kind of jobs, what kind of, you know, healthcare do they have and socioeconomic status. Stress, other things. There's so many other things that can go into that. But they really do think that that disruption of circadian rhythm has serious implications. If you could design the perfect day and the perfect amount of protein
Starting point is 00:17:47 calories consumption sleep yeah intermittent fasting window etc for someone like me i'm 230 pounds uh i'm 40 years old uh-huh as a former athlete i train really really hard. I'm at the gym lifting four or five days a week. I'm doing cardio. I'm doing some running. I'm walking a lot. But I also have a busy lifestyle. I travel sometimes. What would be the optimal, if I could, for me to live longer, still be athletic and strong and healthy and feel great? stronger, still be athletic and strong and healthy and feel great. So that was, you know, I talked about this How Not to Die book, the first half of the book, but I didn't want it to just kind of be a reference book. I wanted this to be a practical day-to-day kind of grocery store guide to make these kind of practical decisions. And that's
Starting point is 00:18:39 what became the second half of the book, which centers my recommendations around a daily dozen checklist of all that kind of healthiest of healthy foods and habits I encourage people to fit into their daily routine. So it's available on a free app. All my work is free at Dr. Greger's Daily Dozen, iPhone, Android. And it's just basically, you know, these kind of to inspire people to include. So, you know, 12 things that we should be doing every day. So, you know, 90 minutes of modern should be doing 12 things so you know 90 minutes
Starting point is 00:19:05 of of modern intensity exercise or 45 minutes of vigorous exercise every single day um you know how much you know how much to drink so i want people to eat dark green leafy vegetables every day the healthiest kind of vegetables i want people to eat berries every day the healthiest kinds of fruits a tablespoon of grown flaxseed a quarter teaspoon of turmeric kind of on down the list um again just to kind of inspire people to kind of think, and they can kind of track their progress, kind of make a game out of it. And look, on the road, I'm not even hitting, you know, I'm lucky if I hit half. But, I mean, it's, again, kind of an aspirational kind of,
Starting point is 00:19:36 if you really did have control over your environment, this is really the kind of things we want to include in one's daily routine. So what are the top five foods that you should eat every day to age longer? Yeah. In terms of anti-aging foods, this Global Burden of Disease Study, which I mentioned before, again, the largest systemic analysis funded by the Bill and Linda Gates Foundation, found that the food associated with the largest expected life expectancy gains are legumes. These beans, split peas, chickpeas, lentils. In fact, one thing we can do is boost our intake of beans or lentil soup or hummus.
Starting point is 00:20:14 And we think it's because they're the most concentrated sources of prebiotics, the resistant starch and dietary fiber that feeds the good bacteria in our gut. And that has implications in terms of decreasing inflammation, improving our immunity, improving muscle strength, muscle quality, muscle mass in frail individuals, all just by changing our microbiome. In fact, you can do these so-called fecal transplant studies where you can- You take a healthy poop and put it in a sick person. It's crazy, right?
Starting point is 00:20:44 And you can actually change their biology. That's crazy. It's absolutely crazy. But that's how we can prove cause and effect. Because like, well, yeah, you feed someone a healthy diet. How do we know their gut bugs have anything to do with it? Ah, well, we can control for that.
Starting point is 00:20:59 And you can do it, you know, and so they, right. So you can make, you know, mice more fit, less fit by giving them, you know. Healthy poop. Healthy poop from an exercising mouse or, you know, from marathon mouse or a mighty mouse versus the, you know, frail mouse. So you can actually change. They're eating the same. They're doing the exact same. But they just have a different stool composition.
Starting point is 00:21:21 And how do you get those good gut bugs? You feed them the right food. And that's the prebiotics. What are good gut bugs? You feed them the right food. And that's the prebiotics. What are good gut bacteria eat? A lot of people are thinking probiotics. They're thinking the actual bacteria themselves, the acidophilus, the bifidobacteria. Those are the good gut bugs. But if you just take those pills, the reason you don't have those good gut bugs in the first place is because you're not feeding them very well. So you can say, you can try to populate your gut with as many good bugs as you want. They're going to die off if you continue to starve them, continue to starve your microbial self. Whereas if you just ate the
Starting point is 00:21:58 right foods, the good gut bugs are fiber feeders. If you eat the right foods then your good bugs will be fruitful and multiply all on their own and you know do all the work for you and that work is creating these so-called post biotics which are their byproducts of microbial metabolism of these good foods like butyrate and essay take it absorbed through the colon wall into our bloodstream circulate throughout our bodies even cross the blood brain, have effects on our mental health, improve our immunity, so dramatically decrease inflammation. You can prevent asthma attacks just by feeding people some beans. I mean, it's absolutely remarkable. So legumes have prebiotics. They have the prebiotics. So that's why we think the food, in fact, legumes are the
Starting point is 00:22:42 primary protein source of every single blue zone ever documented. That's where they get most of their protein, from some sort of legum, whether it's brown peas or something, or black beans in Costa Rica, or soy foods in Okinawa. But it was always centered around not just plant-based in general, but a plant-based source of protein, legumes. So beans. And so we should be thinking like bean burrito, chili, like how can I fit beans in my daily diet? And that's part of the daily does is like,
Starting point is 00:23:10 did I have any beans today? Like, can I put beans in my salad or throw some beans on this pasta dish? And it's like simply get a can of, you know, unsalted, no salt added beans, you know, open in two seconds. You always keep a can of beans in the fridge. You can just throw a spoonful onto anything basically um uh yeah in fact i even said someone at a talk was like i just take white beans mashed into my oatmeal i'm like never heard of that but he's like can't even taste it i'm like okay yeah great i mean look you know and what's nice about a healthy breakfast is that regardless
Starting point is 00:23:40 of what you do the rest of the day you know know, God knows what kind of, you know, what bowl of candy is on your co-worker's desk or what donut shop you're walking by. Or God knows what stress is going to, you know, take you down the wrong path. At least you have a good foundation. Interesting. You have food and you, you know, feed your good and good bugs. Well, anyway, so that's number one on the list. Okay, number one, legumes. Okay, now, so these are, they identify the top five foods that associate with the longest lifespan.
Starting point is 00:24:06 Now, legumes rule the roost on a per serving basis, but actually on an ounce per ounce basis, nuts are associated with the longest lifespan compared to any other type of food out there. What are the three best nuts? There's really only one. There's really only one that pulls's really only one that pulls ahead. That's walnuts. Now, see, normally when I say like, you know, eat, you know, cruciferous vegetables or something, they're like, which one's best? I'm like, whichever one you'll eat. You like broccoli, eat broccoli. You like bok choy, eat broccoli. Like, you know, look, whatever one you'll get
Starting point is 00:24:39 into your face. That's it. But with nuts, it really does, walnuts really do pull ahead. And that's because they have more omega-3s than other nuts. They have more antioxidants than other nuts. And they're the only nuts shown to acutely improve artery function within a matter of hours. And so, and in fact, in the PREDIMED study, which is this large randomized controlled trial over years of thousands of individuals, although mixed nuts certainly did lower cardiovascular disease rates. It was the walnuts that appeared to be the most critical part. And we do want to get unsalted nuts. I know that's not as delicious.
Starting point is 00:25:16 Why unsalted? In terms of dietary risk factor for death, excess sodium intake is the way. So I've been talking about this. Oh, man, but salt is so good. It tastes so good on something. I know. Look, so in terms of things we're missing out on, right?
Starting point is 00:25:29 It's the legumes. But in terms of stuff we're getting too much of. Salt. There's lots of horrible things in our diet. There's sugar. There's trans fat.
Starting point is 00:25:36 There's saturated. Okay. But sodium, salt intake is the number one dietary risk factor for death on planet Earth. Come on. It is the single worst thing about humanity's diet
Starting point is 00:25:45 but there's good news what about like there's good news himalayan salt or something they're different they're all salt to the same huh i know yeah it's but this is pink this is from the himalayans this is rainbow color this has got a few minerals in it or something no no no no no it's all bad oh no but a little bit can you have a little bit well so we want to stick under 1500 milligrams a day that That's the American Heart Association recommendation. And to do that, and most of it, and people are like, I don't add a lot of salt. Most of
Starting point is 00:26:11 our sodium intake comes from processed foods. 70% of sodium intake is not the salt we add in the kitchen or the dining room. It's in these processed foods. These, you know, anything in a box, in a package, in anything, they add salt because it's a flavor enhancer, right? In fact, that's why they add it to a lot of beans.
Starting point is 00:26:28 It's not a preservative. It's in a can. It's sterile. It's because they want to make things taste good. It's the cheap way to make things, you know, so you can't just eat one. But the problem is, is that sodium increases risk, not just of high blood pressure, but so many different leading killers like kidney disease and ice kind of on down the list okay but so there's two ways we can go so there's lots of salt-free seasonings out there um and you know and encourage people to explore all sorts of new you
Starting point is 00:26:56 know and you know people often you know there's all sorts of spices that anyone heard of like saffron and i mean there's so I explore the whole world out there and find some delicious taste. And then the easy fix is switching to the salt substitute, potassium salt. Instead of sodium salt, sodium chloride, switch to potassium salt, which is potassium chloride. It's just a natural mineral mined out of the ground just like the sodium chloride is.
Starting point is 00:27:22 And there are interventional studies. I talk about one in the book where they took these five kitchens at a veteran's retirement home and randomized their kitchens into either continuing to salt with regular salt in the kitchen or switching to a 50-50 blend of regular salt and potassium, so regular sodium chloride and potassium chloride. And there was a tremendous 40% drop in cardiovascular disease death rates within a matter of years in the reduced sodium group.
Starting point is 00:27:52 In fact, their life expectancy at age 70 between the two groups was 14 years. Come on. Meaning that just by switching to half potassium salt, for which you wouldn't even be able to taste the difference, they effectively made themselves 10 years younger when it came to the risk of premature death. So something that, so there's no downside. Wow. There's no, okay. So now, if you go with, I'm encouraging people to actually try to switch to full potassium salt rather than the one in the 50-50 blend, but then you do actually taste the difference.
Starting point is 00:28:24 There's this bitterness to potassium salt that you don't get otherwise. It's more apparent in some foods than others. Some foods you really can taste the difference, but any amount that we can cut down. And the only other caveat is you need to have kidneys good enough to get rid of the excess potassium. And so if you have kidney disease or if you have diabetes, just because diabetes is such an increased risk of kidney disease, it's so damaging to the kidneys. Even if you don't know you have kidney disease, if you have diabetes, you should first get your kidneys tested before switching to potassium.
Starting point is 00:29:01 And, you know, if you're over 70, our kidney function does tend to decline over time. So even if, as far as you know, your kidneys are fine, if you're over 70, I would go super simple test. You can just get your kidney function tested and just make sure your kidneys can handle the extra potassium. But then if you give me all clear, your kidneys are good, then you can get all the saltiness you want. You can add extra, right?
Starting point is 00:29:27 You can make your popcorn as crazy, right? Tears to your eyes salty and with no harm. Wow. No harm. So that's one of the really, one of the simplest tweaks in the book. And it's like the leading cause of dietary risk factor for death, like the worst thing we could possibly eat. And there's a simple fix to it. Like I'm too bad there wasn't like a potassium donut or something.
Starting point is 00:29:49 We just switch over and totally fine. But that was one of the rare things that's like super easy to do. So explain that one more time. So if we have more potassium salt first, then we can have salt? No, we're going, so we're swapping out. So instead of shaking on sodium, sodium chloride, we're shaking on potassium chloride. There's a bunch of different brands. And you can have as much as you want.
Starting point is 00:30:09 And you can have as much, as long as your kidneys are okay. Okay, got you. Right, you can have as much as you want. And so you can go any grocery store. Wow. In the salt aisle, there's all these salt substitutes. I'm going to look at this. And it says potassium chloride.
Starting point is 00:30:21 And there's some 50-50 blends. If you want to start there and move, it's certainly better than adding pure sodium salt i'm going to try that yeah yeah i'm going to try that and the the studies show oh right and not just it's associated with but these interventional trials these randomized control trials blinded they don't know who's in which group until they break the code at the end they say oh my god significantly less death and disability in the group just cutting down on the sodium the same things eating the same exact same things with one single tweak just switching over what kind of salt they're using amazing that's incredible now why haven't we heard about this like why isn't
Starting point is 00:30:55 this on like blary because no one makes any money on it it's like dirt cheap right i mean it's i think it's cheap i think it's more expensive than regular salt. Right, right. It's like five bucks or something. Yeah, yeah. But, I mean, there's just, no one's making money. I mean, there's just not a lot of money made because it's just like a simple, you know, you probably dig it up your own somehow. And so there's just no, yeah, there's just not a lot of profit to be made. Uh-huh. And so, unfortunately, we don't hear a lot about it.
Starting point is 00:31:22 That is fascinating. Okay, so we've heard about legumes, number one. Yeah. Nuts, specifically walnuts, being number two. Palmful a day is my recommendation. Palmful. So, one ounce. What if you want to have more? Oh, look, you can have more.
Starting point is 00:31:33 But the longevity benefits plateau out at one. So, you don't get more additional benefit. And they're kind of pricey. And they're calorie dense. Right. They're calorie dense. So, if you're really active, it's not going to matter. So, 10 to're calorie dense. Right, they're calorie dense. So if you're really active, it's not going to matter. So 10 to 15 a day.
Starting point is 00:31:47 So it's 10 halves. 10 halves. 10 halves comes out to be 30 grams or 1 ounce. Okay, gotcha. So that's, I mean, look, you're not counting. Just grab a handful. Grab a handful. And every day or at least three times a week.
Starting point is 00:32:03 I mean. The benefits are that great. Are that great. And that's in the Adventist cohort. The Lomelan and Adventist cohort, they think it accounts for two years of extra life span. Come on. It is one of the only foods. There's only two foods that have ever been associated with increase in literally years, plural, a single food.
Starting point is 00:32:22 And nuts is one of them. How do they measure this? that know that nuts and beans are going to make you live longer? Okay, so what you do is you take hundreds of thousands of people, you follow them, their diseases, and their diets over time. So you keep doing these dietary surveys, exactly what are you eating, you do these random, call you up, okay, what did you eat in the last 24 hours?
Starting point is 00:32:43 Go through. Sometimes you make them take pictures. Sure, sure. And so you follow that. And call you up. Okay, what did you eat in the last 24 hours? Go through. Sometimes you make them take pictures. Sure, sure. And so you follow that. And then you know their doctors. And so you know, what have they been diagnosed with? What are they dying of? What did their autopsy show?
Starting point is 00:32:54 And so you can follow them over time. That's what's called observational research or epidemiological research. Now, you cannot prove cause and effect with that kind of research because there's confounding factors. Maybe the people who are eating nuts are health nuts and maybe, you know, they're working out. Nut eaters are working out more. Maybe they have other eating other healthy stuff. Maybe instead of instead, what's the other thing you're eating instead of nuts? Maybe you're snacking on some real potato chips. Right. Right. And so maybe it's the benefit. It's not so much the nuts, but you're not eating potato chips. Right. so there's all these confounding facts now there are statistical methods that you
Starting point is 00:33:28 can use to try to control for that so you're basically uh comparing nut eaters who aren't smoking and exercise blah blah blah to nut eaters that the non-nut eaters that also don't smoke don't it and so there be and that's why you need this big number right right and so like the niha rp study the largest study in history we're talking over a half million people. And so with that much data, you can crunch the numbers and really kind of tease out, wait a second. With all these other factors controlled for, the people who are eating this many nuts are living this much longer. That's pretty crazy. And then you can turn to the most powerful evidence we have,
Starting point is 00:34:07 which are interventional trials, where you randomize people to two groups, and you give them a smoothie, one with nuts and one flavored with nuts, but no actual nuts in it. So you make people a walnut-flavored smoothie versus an actual walnut smoothie, and neither the researcher nor the experimental subjects
Starting point is 00:34:22 actually knows which is which. And you test it before and so you really can't tell right um and so then and then you can measure acute reactions you can measure their artery function literally within hours of consumption increase and you can see what's happening their cholesterol what's happening and so then you can so these are kind of those are called um surrogate endpoints so what we'd like to know is let's randomize people to these smoothies for 10 years and see who actually dies who doesn doesn't. Right, right. Okay. You can see how logistically that's difficult to do. But what we can do is we know that, you know, the amount of cholesterol in our
Starting point is 00:34:53 blood, it's a really good indicator of risk factor for, you know, heart disease. And so anything that lowers cholesterol, ah, okay. So we have the observational evidence showing decreased risk of heart disease among non-eaters. And then we have this short-term data showing, look, it improves artery function, decreases cholesterol. No wonder we're seeing these endpoints in the evidence. So you put all the evidence together and you're like, wow, nuts really appear to be healthy foods, right? That's how you do this kind of research.
Starting point is 00:35:19 So fascinating. This is fascinating. Oh, yeah. Good stuff. Good stuff. Okay, we're still on the five things to eat every day. Legumes, nuts, no salt. No salt.
Starting point is 00:35:27 No salt. Unsalted. Unsalted. Or we're keeping our salt intake as low as possible, under 1,500 milligrams. That's not no salt. Right, right. Very minimal. And mostly it's about, if you just avoid processed foods, you're going to go a lot
Starting point is 00:35:39 away there. Way less salt. Way less. So even fresh foods, yeah. Number four and five, what would those be? And so then it's eating more whole grains. So you're having an oatmeal for breakfast, right, instead of bacon and eggs. What about the whole, you know, grain-brain theory and then, like, how grains are bad for the brain?
Starting point is 00:35:55 Right, right. You know, what type of grains affect the brain in a healthy way versus a bad way? Yeah, the kernel of truth, which is kind of a little of a pun for whole grains, is refined grains. Refined grains are terrible for us. So when you take something like whole wheat and you strip away all the fiber and you're left with white flour
Starting point is 00:36:18 or you do the same with brown rice to white rice or you kind of strip out the nutrition and you're left with basically kind of sheer carbohydrates. Or you can take something like a sugar beet, where most sugar comes from these days, actually not from cane, and you basically take all the nutrition away, you're left with table sugar, right? I'm assuming it's like pure calories.
Starting point is 00:36:35 And look, you only have about- No value. 2,000 calories in the calorie bank every day. You cannot be wasting your calories on these empty calorie foods. And so, and where is, and most grain consumption in the country is sadly these refined grains. So going after grains, it makes total sense because that's what people are eating. But of course, it kind of, whole grains got caught in the kind of friendly fire. Right, right.
Starting point is 00:36:58 Right? So what are the grains we should be eating? So, yeah, whole grains grains ideally whole intact grains so like oat groats or steel cut oats the more closely to how they kind of grew out of the ground the better or you know whole grain rye whole you know um um uh you know so you we want whole as the first word in any kind of grain steel cut oats or fantastic or even oak groats, which are what steel-cut oats are. Yeah, oak groats is before you cut it, an oak groat cut two or three times turns into steel-cut oats. But that's the original.
Starting point is 00:37:32 And if you haven't tried it, they are delicious. Oak groats? Super chewy. Oak groats. You buy it. Oh, my God. Someone turned me on to oak groats, and I was like, I'm never going back. Really?
Starting point is 00:37:41 They're so good. And they're so much more healthy. And I can't get back to mushy oats. I'm sorry. I'm never going back. Really? They're so good. And they're so much more healthy. And I can't go back to mushy oats. I'm sorry. I'm sorry. Do you cook them? So you cook them. Now, they take a long time to cook unless you have a pressure cooker.
Starting point is 00:37:54 So if you have one of these electric pressure cookers out on the market now, then it's super quick. 20 minutes, you press a button, they're done. And you can make a whole meal. But it's like oatmeal? It's like a- So it's like, but it's chewier harder more delicious
Starting point is 00:38:06 and no matter how well you chew the reason it's so much better for you is because these bits of go you know
Starting point is 00:38:14 don't get absorbed in our small intestine end up in our large intestine and act as this prebiotic bounty for our good gut bugs but the more
Starting point is 00:38:22 you refine it the more you process it the more you process it the more that gets absorbed high up in the small intestine you're basically leaving your colon bugs to starve down there and that's why the more whole the better that's where the dietary fiber is that's where the resistant starch is that's where we can feed our good gut bugs and they feed us right back Wow okay so that's number four. What would be the fifth thing?
Starting point is 00:38:46 Okay. The fifth thing are foods they want people to reduce. They want people to reduce meat and soda as the two most important things to cut down in one's diet. But interestingly, the top four were actually things people aren't getting enough of. Uh-huh. If you add those things. Right. And so it's possible that really the benefits of a plant-based diet is less about what you're cutting out and more about just including the healthiest of healthy foods out there.
Starting point is 00:39:13 Right. Yeah. I like that philosophy for people because if you can include these things in your system and in your daily routine, you're going to be less hungry for the other sugary processed things. There you go, man. So maybe you have a little bit of it every now and then, but it's not 80%, 90% of your diet. Exactly. It's about, that's the kind of behind the daily dozen thing. It's like, by the end of the day, if you actually check off all those boxes,
Starting point is 00:39:37 you are kind of naturally crowding out these less healthy options. And it turns out over 50% of calories in the United States come from ultra-processed junk. Most of the food we eat is just junk. And so, right, we're just kind of saving for the special occasion. Right?
Starting point is 00:39:55 Doesn't matter what we eat on our holidays, birthdays, special occasions, but on a day-to-day basis, we really should try to eat healthy. And that is centering our diets around these natural foods from fields, not factories, these kind of unprocessed foods. Now I'm curious because we have about 50, 50 men and women that watch and listen, right?
Starting point is 00:40:17 But I'm curious about what, if you could specifically create a super supplement or a stack of supplements every single day for men that they took first thing in the morning, maybe three to five key ingredients, whether it was in a powder or liquid form, what would be those things to have men be optimized, healthier, stronger, more vibrant men? What would those ingredients be? They'd be foods. They wouldn't be supplements. They wouldn't put it in a pill. Now, look, you want to take some berries, freeze dry them, and make them into a powder?
Starting point is 00:40:51 Fine. Sure, sure, sure. If you want to call that a supplement by just eating a spoonful of freeze dried strawberry powder, fine. Sure. Do whatever you want. It really comes down to the foods. We just don't know enough about biology and the human organism to be able to tease out what it is about these thousands of different food components that we can extract it out and make money in a pill.
Starting point is 00:41:11 Now, if people don't, that doesn't keep people from trying. Sure, sure, sure. I tell you, right? That's how you make money. Yeah, of course. Unfortunately, the system is set up with these kind of wrong incentives, right? The worst thing to sell is produce, right? It goes bad. So the most profitable foods are, unfortunately, the least wrong incentives, right? The worst thing to sell is produce, right? It goes bad.
Starting point is 00:41:25 So the most profitable foods are unfortunately the least healthy foods, right? I mean, what you want is a snack cake that sits on the shelf for a few weeks. That's how you make money. I mean, the produce rots on the shelf. It's like the worst. It's like a week. It's good for a week. It's a loss leader for these. It gets people into the store. So they'll buy the really, the stuff that actually makes profit. If you want to make money, you sell brown sugar water in a bottle. It's like pure profit. It's all money. So it's not like the head of these soda companies is sitting around thinking, how can I contribute to the childhood obesity epidemic?
Starting point is 00:41:57 They're just like, how do I maximize profit for my shareholders in the next quarter? And anyone who doesn't think that way gets a conscience they'll be booted out the next day and replaced by somebody who will right i mean right and it's not there's not some diabolical thing it's literally just that's that's how the system works sure sure and so like even a sweet potato grower is not going to put an ad on tv for sweet potatoes because they're not branded like you, you'll just buy their competitor's sweet potato. Like, the whole system is not set up. You're never going to see an ad for sweet potatoes in the Super Bowl because there's just not enough money to be made.
Starting point is 00:42:33 Well, pistachios have done a good job. Wasn't there an avocado one, too? Wasn't there? I don't know. Yeah, but pistachio nuts have, like, blown up. They branded pistachio nuts somehow, right? They're everywhere. Look, look, I'm all in favor i'm i want big broccoli to swoop in and start putting up billboards everywhere right
Starting point is 00:42:50 right if only they had the money right but you've mentioned you mentioned prebiotics being like a key thing yeah yeah for for everyone i guess so what would be you know if you were to create like someone's going to get three to five supplements let's say, or the nutrients that they want to have, whether it's through foods or maybe they didn't have access to those foods, but they can get these prebiotics. What would these ingredients be for men to optimize their hormones, their muscle growth, their stamina, all these different things? Yeah. So why not? Look, if it's the prebiotics that are good for you, why not take prebiotic pills? Why not just take a prebiotic powder? Right? Problem is that we talk about dietary fiber, but actually that term dietary fiber literally covers thousands of different compounds.
Starting point is 00:43:36 And so there's actually thousands of different dietary fibers and they each feed the growth of different probiotic good bugs in our gut. And so it's actually this diversity of all these indigestible plant carbohydrates. That's what dietary fiber is. Indigestible by our small intestine, makes it down to our large intestine. So we cannot be replicated. So there's been experiments using something like psyllium, always a very common fiber supplement.
Starting point is 00:44:02 It can help with relaxation, help with like- Releasing the stool. Regularity, right? But does not have all these side benefits because it's not actually digestible, fermentable by a good gut bugs. It just kind of goes through us. And so we have yet to capture
Starting point is 00:44:18 the complexity of the natural food matrix in actual kind of pill form as much as people have tried. And so, yeah, anytime some new study comes out saying berries are great for you, and it's probably these anthocyanin pigments, the bright, colorful pigments in berries, then instantly supplement manufacturers are like,
Starting point is 00:44:40 boom, there's anthocyanin supplements at every dose possible. Sure. Of course. But the food form of these nutrients is the best form to get them. And there have actually been studies that have actually put things head to head. So it's like, oh, I bet tomatoes are good because lycopene, that red pigment, that's why people, men who eat more tomato products have lower rates of prostate cancer. It's probably the lycopene.
Starting point is 00:45:02 But when you actually give people lycopene supplements, it doesn't work. Wow. And so it's like, okay, well, there's thousands of other things in tomatoes. Let's try something else, right? But it doesn't stop people from making lycopene supplements. It's kind of all the ingredients combined in the tomato or the apple or whatever that gives you the full compounds
Starting point is 00:45:21 that helps your body digest. It's a symphony. And in fact, there's actually synergy. So when you take, there's a famous study that was done on pomegranate and you can fractionate out the pomegranate into, you know, different, based on kind of different compound weights. And when, so when you give,
Starting point is 00:45:36 you kind of drip one component of pomegranates on cancer cells, going human cancer cells, going to petri dish, you know, drops your growth like 20% and you do another combat, but then you add together and you have, and one plus one is greater than two in that they somehow work together and actually have greater drop than all the individual components. So really the whole, I mean, I would love, if there was a supplement, if there was a pill, if there, and there certainly are supplements out there that help people get a unit with sunshine and take vitamin D and alcoholics have been pregnant women have certain, I mean, there's
Starting point is 00:46:08 absolutely needs for supplements. Right. But there's in terms of longevity, in terms of like, I went through and I went into this book thinking I would be recommending some of these supplements that have made a lot of news just because, you know, I'd heard such positive things about them. But when you look in the literature and I would love to, because it's like, that's made a lot of news. Just because, you know, I'd heard such positive things about them. But when you look in the literature, and I would love to, because it's like, that's such a great hook. Like take this one supplement and it's got to do X.
Starting point is 00:46:33 I would love to be able to say that. But they fell one by one. Boom, boom, boom. But what I did find is that these just random foods I had never heard about, like cardamom or, you know, strawberries, one example, or mushrooms have these things that... And just like normal natural foods have these extraordinary effects. It's kind of not as sexy.
Starting point is 00:46:53 You can't just take it a little pill. But on one hand, look, it's delicious. I mean, it's not as convenient, right? But again, it really comes down to the food and And it's just not a lot of money to be made. And so we just don't hear about these studies because there's just no corporate budget driving this promotion. Yeah. This is fascinating, man. This is powerful stuff. I've recently heard more about glucose.
Starting point is 00:47:16 This is becoming more popularized online or at least talked about in the media more as kind of like the more your glucose spikes throughout the day, the faster you age as well. I don't know if you've seen anything in the studies around that. And I've also heard from some experts that either having a little bit of vinegar in the morning or before a meal helps decrease the spike in glucose. Is that an accurate finding that you've seen too? I've got a whole chapter on glycation, one of the aging pathways, and recommend two teaspoons of vinegar with every meal. That's one of the, absolutely. And one of the reasons is because it does this, something called AMPK, because the vinegar is acetic acid in water by definition. And by metabolizing the acetic acid requires energy and that energy drain actually bumps up ampk which is
Starting point is 00:48:06 boosted by exercise boosted by calorie restriction um it's one of the kind of anti-aging pathways um and we can get that boost um by just simple vinegar and it decreases our blood sugars decreases body fat you can randomize people to get vinegar to get to the vinegar drinks sure kind of gross but they used acetic acid versus another kind of acid. It tasted exactly the same, but it wasn't acetic acid and saw significant difference
Starting point is 00:48:33 in visceral body fat, which is the most dangerous body fat coiled around our internal organs, infiltrating our organs. And they did CT scans. I mean, they conjured people, randomized the different kinds of, different kinds of, well, one vinegar or placebo vinegar,
Starting point is 00:48:49 and they did this and saw significant loss. Pounds of body fat difference. Come on. Same amount of calories. Same amount of calories. Just by having vinegar? Vinegar. Vinegar.
Starting point is 00:48:58 Now, the problem with the vinegar strategy is that it gets cleared from our system within 46 hours. That's why you really got to do it at every meal if you want to get that constant boost. Every meal? I know. Okay, so how do you do it? How do you do it? Tell me. So you can like-
Starting point is 00:49:11 You put it in a tall glass of water. You pour a little bit. Yeah. So put in some tea. Dilute it. Put in some water. You've got to, in fact, it can be dangerous taking straight. You can burn your esophagus.
Starting point is 00:49:19 So very important. Do not drink vinegar straight. Wow. Sprinkle it on a salad. Sprinkle it on a- There's all these flavored balsamics out there. So with savory, sweet, there's like dark chocolate balsamic. There's Italian seasoning balsamic. So you can get either curry, there's ginger.
Starting point is 00:49:36 Or you can just do apple cider vinegar. Totally apple cider. Put it in water, drink it. In fact, you can get the benefits from white distilled vinegar that they use for cleaning the bathroom floor. Wow. Because it's the acetic acid. But just in terms of making things flavorful, making things fun, there's ways to add it to your meals. I mean, it sounds kind of gross to begin with, but you just find creative ways to include vinegar,
Starting point is 00:49:58 and it has significant effects on long-term blood sugar control. And on fat loss, too. And on fat loss. And not just any kind of fat loss. Visceral. Visceral fat loss. I mean, people hate that jiggly superficial fat, but that actually has very little metabolic implications.
Starting point is 00:50:12 You can do massive liposuctions on people, get rid of that, get literally over a dozen pounds of that superficial fat, no effect on metabolism, no effect on insulin resistance, no effect on triglycerides, no effect. If you lost that many pounds of fat, period, like if you were doing exercise, you're doing a better diet, you would get tons of benefits.
Starting point is 00:50:30 But that superficial fact that we hate seeing in the mirror, that's not what we should worry about. It's the internal fat. Look, if you want it for cosmetic purposes, whatever. But it's that internal visceral fat called around our organs under the abdominal musculature that that's kind of bulging out the belly that's the serious stuff the good news is your body's smart enough to know that's the most dangerous fat and when you lose weight that's the first fat to go um so we did preference that's why people lose fat they're like why is my arm still jiggly i've been losing all this weight it's because your body's smart enough to know look we'll get get there. Let's do the important stuff first. Wow. So what would you say are the main keys of losing fat, visceral fat and kind of the external
Starting point is 00:51:12 fat? Well, the single intervention that created the greatest loss of body fat that didn't restrict calories. Obviously, you can lock someone in a closet. You can starve someone. Starve someone, right. Or you can change someone to a treadmill. Right, okay. But no exercise component and no calorie restriction, no portion restriction. Eat as much as you want. The most effective body fat at six months and 12 months was this whole food plant-based
Starting point is 00:51:42 diet, was centering your diets around. And it's really kind of a a calorie density factor i mean it's not a restriction it's not a restriction eat as much as you want right but there's so few calories per pound per mouthful per plate in these foods because it's like you can eat a wheelbarrow of leafy greens there's you couldn't even maintain your weight i mean you literally could not fit enough in your stomach. You only fit about a quart of food in your stomach at a time. And so, like, you know, you can get 2,000 calories. You ate two pints of strawberry ice cream.
Starting point is 00:52:16 That would fill up your stomach. You'd be full, and you'd get over 2,000 calories, all the calories you need for the day. To do that same thing with strawberries, 44 cups. 44 cups of strawberries to get 2,000 calories. Like, you couldn't even fit. That's like filling your stomach to bursting 11 times a day. You couldn't even do it physically, right? And that's this concept of calorie density. And so that's why something like oil, people drizzle oil on something. A lot of calories. That is the single most calorie dense food on the planet. Even butter has a little water in it, so it doesn't
Starting point is 00:52:40 have that much calories. One tablespoon, 120 120 calories so you drizzle it on you wouldn't even taste it i mean you'd see it'll be a little glistening or something you just add 120 calories what are you crazy for that same 100 calories you could add like you know uh two cups of blackberries or something that would actually fill you up a little bit right and think all the nutrition you get with that right instead i mean oil may have some fat soluble nutrients a little vitamin e or something but i mean the nutrition has really been stripped away right and so and so and so the caloric density so by staying away from junk food which is designed to have maximum calories per bite you know that can find the fat and the sugar to just absolutely like you have teeny
Starting point is 00:53:19 little you know you get 100 calories just a teeny little bit you have these massive platefuls of food eat all you want and not have to worry about it and that's really and then you're just getting mountains of nutrition for actually very few calories um and so you can facilitate weight loss in a healthy way i mean you know the goal of weight loss is not to fit into a skinnier casket right not to make it lighter for your pallbearers. We want healthy. How about we lose weight in a way that doesn't work with your health? Wow. Yeah. And when you get these calorie dense foods with all the nutritional value, it sounds like there's so much healing properties within these foods that allow your system to self-regulate,
Starting point is 00:54:02 your skin to recover, your gut to recover, your brain to start functioning better. Isn't that right? And calorie dilute foods, not calorie dense foods. The calorie dense foods are the junk food, right? So not calorie dense, but calorie... We want nutrient dense. Nutrient dense.
Starting point is 00:54:18 Nutrient dense. Lots of nutrition per calorie. And so what has more nutrition per calorie than anything on planet Earth? These dark green leafy vegetables, right? Massive amounts of nutrition per calorie. And so what has more nutrition per calorie than anything on planet Earth? These dark green leafy vegetables, right? Massive amounts of nutrition. Actually, for Verdele, it has those nitrates. Those athletic performance enhancing ergogenic nitrates actually help slow our metabolic rate.
Starting point is 00:54:37 And the candle that burns half as bright burns twice as long. That's the other food associated with literally living years longer. Dark green leafy vegetables. Nuts, dark green leafy vegetables nuts dark green leafy vegetables and we think it's because the nitrates normally you only get that kind of metabolic slowing with our resting metabolic rate with severe caloric restriction but instead of walking around starving all the time you can just eat a big salad this is exciting this is exciting. So we mentioned intermittent fasting. Eat in the morning.
Starting point is 00:55:10 Don't skip breakfast if you're going to do that. Most important meal of the day. Really? Most important meal of the day. Here's the thing. This is what doctors were saying for many years.
Starting point is 00:55:17 Yes. Don't skip breakfast. But then in the last seven years, everyone's saying doctors were wrong. Yeah, yeah. Skip breakfast. Allow the body to have autophagy
Starting point is 00:55:26 allow the cell i know you know extend the window where you're not eating as long as you can and that's been the new science so the new studies that have been out where you know skipping breakfast is actually better for you because it's boosting testosterone it's doing all these other things so what i talk about that backlash of that back and forth i actually have videos about it because it's boosting testosterone. It's doing all these other things. So what- I talk about that backlash and that back and forth. I actually have videos about it. It's so funny because you start out the video and be like, yeah, breakfast.
Starting point is 00:55:50 And they're like, oh, okay, breakfast. Oh, and then we're back to the beginning. It's so funny. And so many things in the book like that, like wheat germ or something. That's like, didn't that go away in like the 70s, right? Like the health issue. And then it's like, oh, then there's this thing
Starting point is 00:56:04 called spermidine. It's most concentrated in wheat germ out of all these. All of a sudden, wheat germ is like back on the menu. But it's just so funny. There's like this,
Starting point is 00:56:11 we had some kind of ancient wisdom even before we knew why that it did actually support these foods. So yeah, no, it turns out. Now, it's true about that feeding window.
Starting point is 00:56:20 We do want to try to squeeze it, but critically important is when we're putting that window. In the morning and at lunch. Early time restrictions. Because of the circadian rhythm. That's it.
Starting point is 00:56:27 You got it. So what is the difference between, I guess, bad cells and zombie cells? Oh, this is cellular senescence. So this is one of the aging pathways. So I cover 11 aging pathways, kind of our 11 best opportunities for slowing the sands of time, ending each with kind of impractical takeaways. This is the part one of the book. It is kind of the nerdy section.
Starting point is 00:56:51 It goes really deep into kind of the interesting biology mechanisms, but, you know, really do kind of like, okay, but here's the bottom line. You can skip all this. You know, this is the foods to eat. This is the activity to do, blah, blah, blah. So, yeah, and the cellulose and essence chapter, very fascinating. So our cells in our body only divide about 100 times before they stall out. There's the so-called Hayflick limit.
Starting point is 00:57:13 We used to think cells just kind of, you know, divided forever, but they only divide 50 times. And this is good because that's a protection against cancer. We want cells to naturally kind of put themselves out to pasture, being replaced by new cells from the stem cells. Right. And, you know, the cells can become damaged along the way. Okay, and so at the end of those about 50 doublings, what the cells do is they release these inflammatory mediators,
Starting point is 00:57:38 which signals the immune system to come and kill them, basically come and wipe them out. This is basically their kind of little suicide way. Sure, sure, wave. They're like, okay. So they release these inflammatory compounds, signal the immune system, and it comes and clears out these so-called zombie cells that are no longer participating in the body, actively spewing this, what's called senescence-associated SASP. But okay, the problem is, this works great when we're young. Unfortunately, our immune system starts to decline with age.
Starting point is 00:58:10 And so what happens is our immune system's ability to clear out these cells declines such that our body's tissues get littered with these senescent cells spewing out inflammation. And one of the reasons why levels of inflammation climb with age,
Starting point is 00:58:27 so you can do these kind of blood tests of systemic inflammation like C-reactive protein and tumor necrosis factor, IL-6, etc. And they all go up. And so there's this term, inflammaging. And a big part of this is these cells, which our body shouldn't get rid of, but unfortunately, our ability to do that declines with age. And so, two-pronged approach. First, we prevent cells from going prematurely senescent. So they should make it to 50, but they suffer damage to their DNA from free radicals, from oxidative damage to their DNA as a protective mechanism because
Starting point is 00:59:05 it could cause mutations or something. They kind of go out to pasture early. And so we can decrease oxidatives just by flooding our body with antioxidant-rich foods like the berries and greens and really healthy foods. Okay. So one, so we prevent the premature senescence. That's the first thing. And the second is we look for senolytic compounds, ways to clear these zombie
Starting point is 00:59:25 cells from our bodies. There's been a number of drugs that have been put to the test. Unfortunately, these drugs have kind of some severe side effects. And so there are certain medical conditions in which senescent cells play a key role, in which case the benefit-risk analysis might actually support use of some of these toxic drugs. But for kind of the general public, we're really left with senolytic compounds in natural foods. There are three of them that have been shown to clear senescent cells in the body. One is facetin, which has really only found one place in concentrated form. That's the strawberries. So that's why I end up in the book, in that chapter,
Starting point is 01:00:03 recommending fresh frozen or freeze dried strawberries into your daily diet. Now, normally I would have put like, if you're putting some on your oatmeal or something, I would put like blackberries. Blackberries have five times the antioxidants as strawberries. So look, if you like them both, you know, why not? But, but I didn't know about facetan, which is really only found in strawberries. So if you're not eating strawberries, you're really not getting into your daily diet. So I've been eating a lot more strawberries. Okay, the second, something called
Starting point is 01:00:29 quercetin. Quercetin is found in onions, kale, tea, and capers. It actually plays a role in Mediterranean diet health. And that helps explain these remarkable studies
Starting point is 01:00:45 where they give people onions and see remarkable benefits literally within an hour. You can randomize people eating onions. In fact, you can randomize people to eat high quercetin onions versus bread to be low quercetin onions and show that it does appear to be this one compound. And so, of course, there's quercetin supplements everywhere. It's not clear. We don't know.
Starting point is 01:01:04 What's the best onion? There's quercetin supplements everywhere. It's not clear. We don't know. What's the best onion? Well, it's the, so it's actually lowest in the, in the sweet onions. So like the, of course, like the tastiest onions is low amount. So like the, okay. But so yellow onions have more.
Starting point is 01:01:17 Red onions have the most. So red onions are better than white. So red onions really are the best. So look, and look, you can basically, anything you can do with a white onion, you can do with red onions. So it's like, there's just no excuse. Same thing with cabbage. If you're making something with cabbage, don't go for green cabbage. Go for red or purple cabbage.
Starting point is 01:01:33 It has these anthocyanin berry pigments. One of the cheapest sources of these berry pigments is in red, purple cabbage. Right? Super cheap. And you get those benefits for brain function eyesight artery function inflammation blood sugar cholesterol you get those berry benefits in this kind of savory form is is raw or cooked red onions either way either way either way it's a heat stable oh wait your breath your partner may in fact you need to find you i mean your entire
Starting point is 01:02:03 your sweat can start i mean you can really you can really start as well like i didn't but has there become like too much like you know if you have a half an onion there's only there's only a concern in in supplement form so the supplement manufacturers come out where it's like you could not eat this many onions and then we then we're playing with fire but yeah there's never been any in fact some of these benefits i'm seeing these remarkable clinical benefits we're seeing after eating like one to one onions a day i don't know how one does that without wow i mean that's that's that that's a lot but you can get benefit even from literally a teaspoon of chopped onion you can get uh you can get uh put it on your food and just eat it right right so um and so and this is all the allium family vegetables so it could be like green onions or uh you know so like scallions
Starting point is 01:02:44 or onions, garlic, it's all in this kind of same family and they have these beneficial compounds. The third compound, it's a tough one to get. It's called piper longumine, only found really in one place, which is something called papali or long pepper. It's in the black pepper family. You can get it in Middle Eastern spice stores. And it's basically kind of tastes like black pepper with a little kind of Szechuan heat to it. But it's a senolated compound you really can't find anywhere else. So I encourage people to put some of that
Starting point is 01:03:12 in their pepper grinder to add that to their daily diet. That's amazing. Now, you went to medical school, right? Oh, yeah. In medical school, they don't teach you this stuff. They don't even teach you the basics. Right.
Starting point is 01:03:24 They don't teach you about nutrition. They don't even teach you the basics. Right. They don't teach you about nutrition. They don't teach you about foods. None of that, right? Maybe there's like one hour class on this stuff I hear from other doctors. Yeah, yeah. So how did you get into this world of nutritional science as well when most people today look at doctors skeptically when they're speaking about this because they think, oh, they're not a nutritionist. They're not a scientist around foods.
Starting point is 01:03:50 So how did you get into this world? Absolutely. In fact, having an MD after your name is basically advertising the world that you know nothing about nutrition, that you are completely ignorant about the entire field of nutrition. completely ignorant about the entire field of nutrition. So the average doctor these days gets four hours of nutrition training out of thousands of hours of preclinical instruction. I actually chose the medical school with the largest nutrition training in the country. They actually have a nutrition school at Tufts. 19 hours.
Starting point is 01:04:15 But that's the most out of thousands of hours. Right. And most of it is basic biochemistry of vitamins and like scurvy, pellagra, stuff we don't even see anymore. And it's like curbside. So it's not actually clinical nutrition. Using nutrition diet to actually prevent, arrest, reverse disease. That's missing in even those few hours that people get.
Starting point is 01:04:34 Okay. And so then doctors graduate without this powerful tool in their medical toolbox. To actually heal. To actually help people. Instead, for about 80% that walks into a primary care doctor's office, are these chronic diseases, lifestyle diseases, like the high blood pressure, type 2 diabetes, and the obesity, and the heart disease. And yes, we have drugs that can slow down the rate at which our diabetics go blind and lose their kidney function and lose their lower limbs.
Starting point is 01:05:01 But not reversing it. But not actually make our patients better. That's why we went to medical school, right? We want to actually heal people. But instead, I mean, it's just so frustrating because unless you treat the cause, the underlying cause, you're not actually going to reverse the disease. The root.
Starting point is 01:05:18 Right, the root cause. But that's the exciting thing about lifestyle medicine. Okay, so how did I get into this whole lifestyle medicine thing? Proud to be a co-founder of the American College of Lifestyle Medicine, now the fastest growing medical specialty in the country. Very exciting. Okay, it all started with my grandmother. I was just a kid when my grandma was sent home in a wheelchair
Starting point is 01:05:41 basically to die with end-stage heart disease. She already had so many bypass surgeries, she basically kind of ran out of plumbing at some point. So confined to a wheelchair, crushing chest pain. Her life was over at age 65. Oh, man. And then she heard about this guy Nathan Pritikin, one of our early lifestyle medicine pioneers.
Starting point is 01:06:04 And what happened next is actually detailed in Pritikin's biography of our early lifestyle medicine pioneers. And what happened next is actually detailed in Pritikin's biography. It talks about Francis Gregor, my grandmother. They wheeled her in and she walked out. Though she was given her medical death sentence at age 65, thanks to a healthy diet, she was able to enjoy another 31 years on this planet until age 96 to continue to enjoy her six grandkids,
Starting point is 01:06:24 including me. That's why I went into medicine. That's why I practiced lifestyle medicine, why I started the website NutritionFacts.org, why I wrote the book How Not to Die, why all the proceeds from all my books are donated directly to charity. I just want to do for everyone's family what Pritikin did for my family. Wow. Now, did you think about that going into medical school?
Starting point is 01:06:46 Absolutely. That was a- So you knew going into medical school, they're not teaching me the things I still need to know. Yeah. Yeah, yeah, yeah. So when did you learn all this stuff about lifestyle, nutrition, diet, foods? Was it all after medical school?
Starting point is 01:07:00 No, the big pivot was in 1990, before medical school even started. And that was the publication of the Lifestyle Heart Trial from Dean Ornish and colleagues. So what Pritkin was doing, he was reversing heart disease by the thousands, but back then, we did not have the technology to actually look inside people's arteries, so it was a clinical diagnosis. You have chest pain when you walk upstairs, you've got heart disease. Okay, so we put you on drugs and we cut your chest open. We do bypass, we stents, whatever. Okay. Then Pritikin would take these people and then put them on his
Starting point is 01:07:29 diet and lifestyle program. And all of a sudden chest pain goes away. And so he reversed heart disease. Now the medical profession was like, no, no, no. Heart disease gets worse, worse, worse till you die. That's what the thinking at the time. And so if your patient is fine, he never had heart disease in the first place, right? It must've just, right. It must've been something else. And so that was, so he was kind of remained on the fringe until Dr. Dean Ornish came along. He used something called quantitative angiography, where you actually, you, you inject a radio pig dye into the arteries, right? You do these x-rays. You can actually see the inside of the arteries. And so for the first time, was able to prove the reversal of heart disease, opening up arteries without drugs, without surgery,
Starting point is 01:08:11 just a healthy plant-based diet and exercise. And so that was really, and it was published in the most prestigious medical journal in the world. So it was like unassailable science, randomized controlled trial. Of course, the people in the control group who were told to continue to eat whatever their doctors told them to eat continued to get worse. That's what happens normally. Whereas you've got this reversal on average in those. And so it's the only diet ever been proven to reverse the progression of heart disease in the majority of patients. So it's like, look, if that's all a plant-based diet could do,
Starting point is 01:08:46 reverse the number one killer of men and women, like, shouldn't that be kind of the default diet until proven otherwise? And the fact that it can also be so effective in preventing, arresting, reversing other leading killers like high blood pressure and type 2 diabetes, which surely make the case for, you know, plant-based eating really kind of unassailable at this point. And so, but then, here I am. So now, I had already known about this from my grandma, right?
Starting point is 01:09:07 But here I was in black and white publishing, you know, the most prestigious medical journal. And so, you know, you just imagine all of medicine changing. Here we are decades later. That was 1990. Here we are over three decades later. Hundreds of thousands of Americans continue to die from heart disease. A preventable, arrestable, sometimes even reversible condition, which we've known about
Starting point is 01:09:31 for decades, just because this has yet to really penetrate into the medical field. And that's because the incentives are wrong. Actually, you know, hospitals make money cutting people open. And these are the golden goof for big pharma, lifestyle drugs, where instead of 10 days on an antibiotic to save your life, it's take a drug every single day for the rest of your life. That's how you make money, right? But the only drug you need that for is these lifestyle diseases
Starting point is 01:10:01 where if you continue to treat yourself like this, well, of course you need something. And look, if you refuse to improve your life, then these drugs can be life-saving. I mean, so, but even better, why not try to reverse the disease by treating the underlying cause in the first place? So when you finished medical school, did you start going right into this nutritional side of learning as well? Well, so, yeah. So I started out in clinical practice, like, but then I realized, like, even though, you know, I don't know how, how many people you could pack into a day, you
Starting point is 01:10:31 know, how many people am I reaching? Right. So people were dying everywhere. And so then I, so I started, you know, giving lectures, um, and going around to medical schools and trying to train the kind of next generation of doctors. But even then, like how many people can you reach? You know, you can reach hundreds, right? So then I started, this was actually so long ago, it was like a VHS series.
Starting point is 01:10:51 I started making, well, why don't I tape these lectures, right? And then send out these VHS tapes. We started into DVDs until finally was able to put it online. Yeah, of course. And then can reach millions with that same kind of message. So now I'm so, had to give up the clinical practice. So I feel like I'm still practicing medicine, but just on a kind of broader scale, writing, research speaking,
Starting point is 01:11:11 all that, just getting this information out there. It's like, in a certain sense, we really don't need any more research. We have enough to save so many lives, and there's always unanswered questions. Of course. I love the research, but we have enough now to really reverse the course of the way our country's headed. So it was a lot of your learning then based on just studying research papers and clinical trials and then kind of assimilating the research and saying, hey, this is the findings.
Starting point is 01:11:38 Why don't we start trying these things with patients and see the results? Yeah. So it's all really the gold standard of what we know in medicine comes from the so-called peer-reviewed medical literature, right? So these are the studies in these peer-reviewed medical journals where at least this is kind of bar to entry. Like on the internet, you can say anything, right? Earth is flat, whatever, right? And look, you can say there's crazy things published in the peer-reviewed literature
Starting point is 01:12:01 as well, but at least there's kind of a bar to entry where fellow scientists actually look at your work with kind of a skeptical eye and make sure you just like not totally making stuff out of whole cloth right and so that's where we look to and so there's been decades decades of this this mountain of research building up but it just hadn't hasn't kind of gotten over the general public again just because there's not money to be made right so new blockbuster drug oh my god there is a press release there is ads on tv everybody knows about the new drug which could have even a fraction of the benefit as the and so i feel like we're in a very similar situation to kind of smoking in the 50s in the 50s we had already literally recommended
Starting point is 01:12:42 cigarettes decades of research starting in the 30s linking lung had already literally- Doctor recommended cigarettes. Decades of research, starting in the 30s, linking lung cancer and smoking. And so yet, the average per capita cigarette consumption in the 1950s, 4,000 cigarettes a year, meaning the average person walking around smoked half a pack a day. That's crazy. Most doctors smoked. The media was telling people to smoke. The American Medical Association said smoking in moderation. That was fine, right? And so by the time 1964, when the first Surgeon
Starting point is 01:13:12 General's report came out, and smoking rates went up, up, up until 1964, then in one of the most remarkable public health victories of all time, basically smoking rates have come down every year since and down this tumbling lung cancer rates. It's just the most beautiful graphs, you know, all public health. And what happened in 1964, the first Surgeon General's report, just this acknowledgement by the powers that be that, okay, yeah, smoking isn't good for you. And they cited 7,000 studies, right?
Starting point is 01:13:42 So you'd think maybe after the first 6,000 studies could give people a little heads up or something, right? So I feel like we're in the same situation today where there's this absolute mountain of evidence. It just has yet to kind of make it into the public consciousness, make it kind of bypass these barriers. And so that was really like that's my role is I'm going to take, right? It's not me saying this. Right. It's just like this is what the established science is already there. But there's just kind of no sexy money to be made. Right. And it doesn't make those headlines. No one wants to see broccoli on the cover of a book. Sure. Right. It's just like it's like it has everything working against it, except who profits. Except who profits?
Starting point is 01:14:23 I mean, the people profit. Your family profits. Your longevity profits. And so it's just crossing that gap, getting that information out to the public. I mean, you mentioned that. 1964 was when they came out and said smoke is essentially bad for you. 60 years ago. Is that right? 60 years ago?
Starting point is 01:14:50 right 60 years ago we it seems to me like 80 of americans know that sugar and processed foods are not healthy for you it seems to me by now there's enough information out there that people at least have that awareness but they stopped they haven't stopped right consumption right the behavior right what do you think it's going to take for people to change the behavior and the habits to consume healthier foods so they can actually live longer as opposed to suck to the addiction of feeling and tasting good? Right, right. Well, you know, towards the end there with the smoking, in the smoking crisis, most smokers had an inkling that smoking was not good for you.
Starting point is 01:15:26 But what the industry's tact was, was just to muddy the waters. They knew they were going to lose in the end. They're going to confuse you. Right? And so, in fact, there's this famous memo which was uncovered in the tobacco trials, this internal memo called Doubt is Our Product. So this is a PR company that worked with Phil Morris to, we don't have to convince people smoking is good for you.
Starting point is 01:15:49 We lost it. Okay. All we have to do is introduce doubt. Yeah, maybe it causes lung cancer. Maybe it doesn't, right? And that's all you need for someone who's addicted to smoking to be like, well, look, they say it's okay, right? And so now it's the same thing, right?
Starting point is 01:16:02 It's like we are bombarded by ads for fast food, for junk food, for candy, for soda. At the same time, the science is so clear, but we're getting these mixed messages. And you know when everybody wants to hear good news about their bad habits. And so when there's like, well, this person says alcohol is good for you. I mean, right. And so even if all these people right. And so even if all these people are, and so that's all you need is that, and then you just kind of continue down your path. Right. And so that's what the 1964 did was just like, okay, there's scientific consensus
Starting point is 01:16:36 now. Anyone who's telling you that smoking is not bad for you is a pain shill of the industry. And it's like, this is like, this is the established science. Although, you know, it's hard to imagine that even happening these days. What if the CDC, the government came out and said, you know, yeah, it turns out that processed meat, bacon and hot dogs, lunch meat, we determined that they increase the risk
Starting point is 01:16:58 of colorectal cancer. In fact, there's a known human carcinogen. It's true, group one carcinogen, meaning we're as sure that processed meat causes colorectal cancer as we are that plutonium causes cancer and tobacco causes cancer and asbestos causes cancer. We are sure it causes cancer. And yet, you know, we're sending kids to school with a bologna sandwich or something, right?
Starting point is 01:17:17 We wouldn't maybe smoke around our kids now, but we're sending them. And colorectal cancer is the single deadliest cancer among non-smokers that's our number one can if you don't smoke your number one cancer nemesis in terms of dying colorectal cancer and right and we okay so so this this science has been established has not yet but what if the cdc the government finally came out put it on their website okay yeah process me we probably shouldn't be feeding this to people in today's media world you know back then like we like to i mean certainly me i like to think of the internet as this right democratizing force like you know we all this idealistic view of like now like the truth is
Starting point is 01:17:58 going to float to the surface right if everybody in free marketplace of ideas right um and so you know back in the night back in thes, tobacco could absolutely control the message. They can pay off the doctors. In fact, the American Medical Association, even after 1964, tobacco, even after the Surgeon General's report came out, they refused to endorse it. And it turns out later that a 10 million dollar check for the tobacco industry. Wow. Which they didn't disclose anyway. OK. So look, you could pay off the doctors. You could control the message. You control the media, right? Now, which is in part good. There's no longer that kind of monopolistic control of the message, right? But there's confusion. But what you, it's replaced with, with confusion. So even
Starting point is 01:18:39 if these days we had the quote unquote authorities, the experts that came out and said X, Y, Z. A lot of people wouldn't believe them. Now for good reason in many cases, because there's been so many terrible crises with drugs that were promoted and then turned out to be terrible and pulled from the market. And look, all the authorities were telling people to use these drugs. Anyway, so it's hard to imagine a similar kind of aha moment with diet that we saw with this kind of clear surge in general thing. And so there's always going to be the sugar pushers. And there's always going to be these people that are muddying the waters just enough to introduce enough doubt that people will kind of throw up their hands and eat whatever
Starting point is 01:19:26 crap's put in front of them, which is how the industry makes money. I've got a few questions for you left, but I'm excited for people to check out your book, How Not to Age, the scientific approach to getting healthier as you get older. And I think a lot of people think about, you know, how do we, how do I make my biological age, right? Reverse. Essentially, you can't reverse chronological age, but how do we make our cells younger, right? How do we make our body, our cells younger? Is that the difference between the chronological and biological age? Exactly, right. There's the calendar age that just keeps going forward until we get a DeLorean or something. But then there's the, right right but just because we happen to have this many birthdays
Starting point is 01:20:08 doesn't necessarily mean our body is functioning as if it could be worse we get a be have accelerated aging and that we really should have the heart and the kidneys and the liver of a 50 year old but they're actually functioning like a 60 year wow right we actually have the muscle mass of a 60 year old we actually have that or alternately we take care of ourselves and we have tremendous power over this leeway. Or yeah, I've had 50 birthdays, but I have the aerobic capacity of a 40 year old. And so that's this difference.
Starting point is 01:20:38 And so there's lots of different ways to measure biological aging. And so just a fascinating field of science. But the bottom line is that we really have tremendous control over that leeway. That's cool. And literally just, and it's never too late. I mean, so there's the first studies that came out, it's like, okay, well, if you started at age 20 and you do the X, Y, and Z, by age 50,
Starting point is 01:20:59 you'll have all these benefits. And it's like, yeah, that's great, but you should have told me that 30 years ago. Sure, sure, sure. But then they found, wait wait a second even in the 80s this is the latest that's been done but even in people's 80s there's still literally years left on the table healthy years left on the table just by simple basic lifestyle changes um and so those uh those those few things i mentioned before not being obese not smoking uh regular uh aer exercise, and more fruits and vegetables can, over the subsequent four years, if you're between the ages of 45 and 64, decrease your risk of all-cause mortality by 40%. Wow.
Starting point is 01:21:36 Meaning your risk of dying by anything over the next four years. By 2028, you want to reduce your risk by 40%, just do those four things. I mean, that's, I mean, so that's like, we have tremendous power over, you know, look, you still get hit by a bus. I mean, there's lots of things. Sure, sure, sure. So don't wear a seatbelt, smoke alarms, all that, right? But in terms of what's the most common cause of death, actually, we have so much control.
Starting point is 01:22:00 And unfortunately, we just don't hear that message. What are the four main things? Okay, so not smoking, not being obese, regular exercise, which really comes out to like 22 minutes a day, which is what the cutoff point was, and five daily servings of fruits and vegetables minimum, right? And that's not a lot. We're not talking about cutting out meat. We're not talking about like any of these like dramatic changes,
Starting point is 01:22:22 not all or nothing, like just like these really core kind of, yeah, we heard about five fruits. But it's like, wow. I mean, that makes this massive amount of difference. Now, you want to go beyond that and like, you know, tweak even further? Yeah. We got also there's certain fruits and vegetables that are even better than other fruits. But let's not get lost in the weeds here. Just do these simple things.
Starting point is 01:22:43 Let's do the simple things. That'll get us most of the way there wow this is fascinating michael i'm so grateful for your your excitement and passion around this and your wisdom and knowledge um a couple final questions this one this one is something i ask everyone towards the end of our conversations it's called the three truths so i'd like you to imagine a hypothetical scenario you get to live as long as you want to live. You get to continue to write all the books and speak 200 times a year like you do a lot of the times to spread this message. And you experience life the way you want to. All your dreams come true.
Starting point is 01:23:18 But it's the last day for you. Far in the distance. And in this hypothetical scenario, on your last day, you have to take all of your work with you. No one has access to this book or this conversation or anything you've ever written or said ever. Oh, you're killing me. It's gone to another place. Okay. But before you die, you get to leave three things behind.
Starting point is 01:23:39 Three lessons. Three truths. Yeah, yeah, yeah. It could be about your work. It could be about your work. It could be about personal life. It could be about whatever you believe that you would want to leave behind, these three lessons to the world. What would be those three truths for you?
Starting point is 01:23:56 Well, I mean, certainly a truth for me, you know, it's always hard to give advice to other people, right, obviously. to give advice to other people, right? Obviously. But what's certainly been true for me is my, what I've dedicated my life to, this kind of reducing unnecessary suffering in the world. That has given me, having that, having that motivation, having that vision,
Starting point is 01:24:21 having that base truth in my life has, like, so even if all my good works were to nothing, it would have benefited me to have woke up every day and been able to look myself in the mirror and be like, you know, there's just so many horrible things happening in the world, but, like, I did my part. And so that would be the message. It's like, if you can configure your life to not just do what you're good at and not just to, you know, but to do something meaningful for others able to look outside because I had my basic needs met. But so that would definitely be one of the truths is to, you know, incorporate some
Starting point is 01:25:12 kind of selfless action. Look, and that could be philanthropy, right? I mean, you could be, you know, it doesn't have to mean devoting your career to that. But, you know, like tithing, you know, even 10% to, you know, there's so much we could do with you know like bed nets for malaria and stuff you can save literally save people's lives for you know small amounts of money right if you actually save someone's life if you went into a burning building and you pulled out some kid that would be the biggest day of your life like that you would remember that that would be like your crowning achievement you would never forget that it would have been worth it right you can do that with a check these days because now we have a system where we can get money anywhere in
Starting point is 01:25:50 the world to places that really needed we have preventable diseases and we have tremendous poverty that can be alleviated and it's like that's this amazing we have this amazing power that we never really had in our species before to help you know we have this tendency obviously to help people around us people are close to us we see something and we have this tendency, obviously, to help people around us, people who are close to us. We see something and we want to reach out to something local. I totally understand that. But, I mean, you know, poverty here is nothing like poverty some places in the world.
Starting point is 01:26:14 And one dollar can go so much further. So far, yeah. And so that's, you know, that's another thing that I've really learned is that you can help, I mean, you can be that crazy hero that actually saves somebody's life. Amazing. Regardless of what you do in your life, by giving just a little bit.
Starting point is 01:26:32 We really have tremendous control. I know we don't like to think about these horrible things, but you know how you don't think about these little horrible things? Is you actually do something about it. Right. We don't want to think about it because we have this guilt, you know?
Starting point is 01:26:43 And so you don't have the guilt when you feel like I am part of the solution. Taking action, yeah. I am taking action and I'm actually, in fact, I'm helping and even if I could help more and I'm not helping as much as I possibly could, look, I'm helping more than like 90% of the people around me. Yeah, of course. Even given 10%, how many people actually give 10% of their income, right? Particularly people who are making enough that they wouldn't really even notice the 10% in the end of the day.
Starting point is 01:27:09 Yeah. And so the fact that, you know, there's this really this beautiful culture of giving in this culture, in this society. You know, I just came back from Europe and there just really isn't this like thing of like donating to like nonprofits. And there's just not that kind of like you know the billionaires there are just like keeping all the money themselves whereas you know billionaires here are doing these massive projects and i know we love to hate on the billionaires but but i mean they actually do some good things they can do and we should be like applauding them when they do it and not just like you should get more exactly oh yeah Oh yeah. Okay. Well,
Starting point is 01:27:45 yeah. And they should, but yeah, of course. Okay. So that's your first one. Okay. So first through live to your values.
Starting point is 01:27:52 Um, uh, and, and then the second one, if you can, I mean, we want to separate that out, um, to actually act on those values,
Starting point is 01:27:59 even if it's not in a career, you can do it with, with money, with resources. Um, another core, um, core truth, with resources. Another core truth. Third truth. Give me a truth that is in all that otherworldly thinking, you need to hold a place for love, self-love and not only self-love, but, you know, surrounding your people and having surrounding yourself.
Starting point is 01:28:30 And we're just kind of we're these social beings. We just evolved to be, you know, to be able to have to have that. And as much as like, you know, I'm just like workaholic for the whatever. I've really learned too late in life, I'm afraid. workaholic for the whatever. I've really learned too late in life, I'm afraid. Really? And that, you know, I really have to, you know,
Starting point is 01:28:53 you put on your own mask before you help others. And it's not because you're selfish. It's because you can't help others if you're not taking care of yourself. And so, yeah. And so making sure and to really cultivating love in your life is is something that I wish I would have emphasized earlier. And almost it almost seemed like selfish to me. Right. It's like, what do you mean? I mean, but there's so many people out there that I could be helping. Right. To like put all my energies into like one person or into, you know, it seems almost like, well, of course, man, of course I want to help because I'm close to them but it's like that's almost seems like you know unfair but but the wisdom I've learned later the truth I would pass on
Starting point is 01:29:34 to my earlier self would be to really to that has to be a priority Wow because that's so much of that is life it's it's from kind of a like a lifelong perspective it's the feeling of the work i've done both kind of on a day-to-day happiness like on a literally like how are you feeling right now on a day-to-day that's it's the loving relationships in your life those are great truths those are beautiful do you have love in your life right now i don't have enough love in my life unfortunately um and what action are you to take this year well yeah well that cultivate more love that has been yeah well i mean that that i mean if this is i'm a tough person i'm a tough person to love just because you know i'm i'm
Starting point is 01:30:16 i'm so kind of your time i'm so i'm so neglectful of my of my relationships with friends and family as much as I love them because there's just like the world's on fire. I can do something about it. And like I feel myself and the more uniquely positioned I am to help. Like before when I was a kid, it's like I'm like bulk mailing envelopes for the local like homeless or whatever. Sure, sure. But like if I wasn't doing it, somebody else could do it. But the more I get like, well, if I'm not doing this. Specialized, yeah.
Starting point is 01:30:46 Right, it's like, well, if I'm not, if this, if I don't get this done, it's not like somebody else is just gonna scoop a swoop in and do it. And so I feel this like additional burden to do it. But, so, but, so, speaking tour. This is your third tour. This is one of your most,
Starting point is 01:30:59 if you could only think of three things to do in the world. I know, so that's, well, so I going to meet a lot of people on this speaking tour. And hopefully, I will find the love of my life on the road. So you're sending that intention. I'm sending that intention out into the world. OK, great. All right. There you go.
Starting point is 01:31:18 But you could also do that with friends and family. I can also. Be a little more intentional. Absolutely. It's true. It's hard. When we get so obsessed into our mission, it's hard to remember to text or call or you know absolutely i understand that feeling but i love you mom yeah that's good it's good give her a call today that's
Starting point is 01:31:36 right that's right um i want to acknowledge you michael for your commitment to your mission your commitment to wanting to put together great work where you're finding all the best research you can find and packaging it so we can understand it and, uh, you know, sharing your findings so that we can hopefully live healthier, longer, better lives so that we can enjoy the fruits of connection and love with people around us. And, uh, I want to acknowledge you for acknowledging that as well. That it's something you get to work on in your own life. That's right.
Starting point is 01:32:07 I think, you know, saying that truth and owning it is a great thing to say. And so having that intention this year, I think I'm excited. Hopefully by the end of this year you send me a photo.
Starting point is 01:32:18 I'm reporting back. Absolutely. You have the love in your life. Whether it's one person or friends or family. That's right. Just more love in general. You get invited to the wedding. friends or family. That's right. Just more love in general. You get invited to the wedding.
Starting point is 01:32:26 Let's go. Let's go. People can get the book, How Not to Age, the scientific approach to getting healthier as you get older. Make sure you guys grab a copy. You've got a few other great books as well. Where can we follow you, support you, and learn more about your work as well? So all my work is available free at nutritionfacts.org. There's no ads, no corporate sponsorships, strictly not commercial, not selling anything.
Starting point is 01:32:50 Just put up as a public service, as a labor of love, as a tribute to my grandmother. That's beautiful. That's so nice, man. I love it. Final question for you. What's your definition of greatness? Is living true to your values. Living true to your values. Living true to your values. Whatever those values
Starting point is 01:33:07 are, you know you should do the right thing. But are you actually doing what you know? You're not being convinced otherwise. No, no. You know what's right. And are you actually doing it in the back of your mind? You know you could be a little
Starting point is 01:33:23 bit more true to your inner self, but are you could be a little bit a little more true to your inner self but are you actually doing it are you going all in on it right ah ah that's that's greatness it's like being your own superhero basically it's like and no one knows what you're capable of but you yeah then and you know and people could be like patting you on the back oh my god you did awesome but you know you could have studied a little more you could have done this a little more now it's that feeling that like no no I put in the work
Starting point is 01:33:53 and I did absolute look I could have done better but I don't have the capacity to do better but I did the absolute best I could and look it doesn't matter what the outcome is did you really do what you know it was possible that's greatness yeah Michael thanks so much for being here I hope you enjoyed today's episode and it inspired you on your journey towards greatness make sure to check
Starting point is 01:34:17 out the show notes in the description for a full rundown of today's episode with all the important links and if you want weekly exclusive bonus episodes with me personally, as well as ad-free listening, then make sure to subscribe to our Greatness Plus channel exclusively on Apple Podcasts. Share this with a friend on social media and leave us a review on Apple Podcasts as well. Let me know what you enjoyed about this episode
Starting point is 01:34:41 in that review. I really love hearing feedback from you and it helps us figure out how we can support and serve you moving forward. And I want to remind you, if no one has told you lately that you are loved, you are worthy, and you matter. And now it's time to go out there and do something great.

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