The School of Greatness - Unlock the Power of Sleep: 3 BRAIN HACKS to Transform Your Neurological System

Episode Date: December 15, 2023

Sleep is powerful. You’ve probably heard this statement a thousand times. It’s all over the books, media, podcasts, videos, everywhere. But many of us still lack a deep understanding of its power ...and how to use it for our benefit. In today’s episode, 3 guests dive deeper into understanding the amazing human mind and how sleep is critical to operating at 100% mental capacity. We talk about how to unlock its power — particularly during really hectic seasons of life.Andrew Huberman is a neuroscientist at Stanford University. He also runs the Huberman Lab, which studies how the brain functions, how it changes through experiences, and how to repair the brain after injury or disease. David Sinclair is a tenured Professor in the Department of Genetics at the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School and serves as President of the Academy for Health and Lifespan Research. He is best known for his work on understanding why we age and how to slow its effects.Dr. Matthew Walker earned his degree in neuroscience from Nottingham University, UK, and his Ph.D. in neurophysiology from the Medical Research Council in London. Dr. Walker researches the impact of sleep on human health and disease, and he’s written the international bestseller, Why We Sleep, unlocking the power of sleep and dreams.In this episode you will learnHow inadequate sleep impacts brain function and overall mental health.The ideal amount of sleep necessary for optimal health and well-being.The effects of a poor diet on sleep quality, even when you're getting sufficient sleep, compared to the impact of a good diet on nights of poor sleep.Ways to influence and potentially control the nature of your dreams.Techniques to train your brain for more frequent lucid dreaming experiences.For more information go to www.lewishowes.com/1545For more Greatness text PODCAST to +1 (614) 350-3960Listen to the full episodes here:Andrew Huberman – https://link.chtbl.com/1219-podDavid Sinclair – https://link.chtbl.com/1004-guestMatthew Walker – https://link.chtbl.com/1476-pod

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Starting point is 00:00:00 Sleep is the fundamental layer of mental and physical health. If there's one thing that we should all be doing is working toward sleeping long enough and deeply enough, there are a number of risks to not getting enough sleep, but the primary one is a... Welcome to the School of Greatness. My name is Lewis Howes, a former pro athlete turned lifestyle entrepreneur. And each week we bring you an inspiring person or message to help you discover how to unlock your inner greatness. Thanks for spending some time with me today. Now let the class begin. Welcome to this special masterclass. We brought some of the top experts in the world to help you unlock the power of your life through this specific theme today.
Starting point is 00:00:51 It's going to be powerful, so let's go ahead and dive in. Until you are sleeping long enough and deeply enough, 80% of the nights of your life, you are functioning suboptimally. And what's the biggest risk then if we're not getting enough sleep? Okay. So there are a number of risks to not getting enough sleep. Deficits in learning, deficits in the immune system, reduction in testosterone and estrogen in both men and women. So disruption of hormones, disruption of gut microbiome, increased cancer risk. There are a bunch of things. The severity of those things depends on a lot of other things too. Prior health, other health conditions, context, age, occupation.
Starting point is 00:01:38 If you're not getting enough sleep and you're a high-rise construction worker, it's different than if you're an office worker. So we need to sleep enough. Now, what's enough sleep? This is an interesting question. Enough sleep has been argued at six hours. Other people, it's seven hours. Other people, it's eight hours. It's basically waking up without an alarm clock and feeling rested. Insomnia is actually a medical term nowadays. And insomnia is essentially diagnosed as falling asleep during the middle of the day due to lack of sleep at nighttime. But many people who are having trouble sleeping at night are not falling asleep during the middle of the day. They're dealing with grogginess or crankiness or other
Starting point is 00:02:25 effects of having fragmented sleep. What are the main causes of not being able to fall asleep? Is it rumination? Is it traumas that you're holding onto? Is it arguments? Is it self-doubt or insecurities? Is it your nap too much? Is it the foods you ate too late? Like what would you say are the main causes of not being able to fall asleep? All of the above. But the primary one is a failure to turn off your thoughts. Okay. And I think that might provide a good anchor point for us to talk about some protocols. Really a excellent night's sleep begins in the morning. I talked about this on the previous episode, so I won't go into detail,
Starting point is 00:03:10 but everyone should get as much bright light in their eyes, ideally from sunlight first thing in the morning, 10 to 30 minutes outside, depending on how bright it is. Eyeglasses or contact lenses are fine. Don't wear sunglasses if you can do it safely. If you wake up before the sun rises, turn on bright lights, then go outside once the sun rises. If you have no access to sunlight, use a daytime simulator or similar like a ring light and get that light in your eyes. Okay. So that's all of that in a compact form. Caffeine. You can inhibit falling asleep with
Starting point is 00:03:40 caffeine. You have to figure out when your threshold is. For me, I can drink caffeine up until about three, even four o'clock in the afternoon and sleep like a baby. And still sleep well. Yes. And Matt Walker, our good friend Matt Walker, would say that my sleep isn't as good as it would be had I cut caffeine out earlier. By like 11 or 12 a.m. Right. And I want to acknowledge, you know, Matt is the Michael Jordan of sleep science. And so I'm not going to. You're the LeBron James. Well, no, no. And thank you for the compliment. But no, I'm not.
Starting point is 00:04:13 I know a lot of the science and the protocols, but that's Matt's wheelhouse. And so if he says something, it's true. And if I say something and our opinions conflict, it's likely to be something that the data are still emerging or in that case, default to Matt being correct. Because I just out of due respect for his expertise. So caffeine, you know, for some people they can have a two o'clock espresso, 2 p.m. espresso. Some people it's 4 p.m. Some people can drink caffeine at 8 p.m. and fall asleep. But there I would say it's problematic because you're disrupting the architecture of sleep and the brain waves associated with sleep the chemicals and so forth so get that morning
Starting point is 00:04:54 light cut your caffeine off at the time that allows you to fall asleep that morning light also sets the timer on your melatonin rhythm so you have this gland in your brain called the pineal gland. That pineal is the source of melatonin. Melatonin makes you sleepy, but it does not keep you asleep. Okay. Melatonin starts to rise in the late evening and continues into the night
Starting point is 00:05:17 and then eventually tapers off. This is naturally occurring melatonin release, not supplemented melatonin release. The fastest way to slam melatonin to the pavement and eliminate it in your system is to look at bright light for, I hate to tell you this, even a few seconds. You mean at night? At night is typically when melatonin rises. It's when it's released in the bloodstream, and when it has this effect of making us sleepy,
Starting point is 00:05:43 it does a number of other things too. You want more melatonin at night, is that right? You do. And if you wake up in the middle of the night or it's eight o'clock and you decide that you want to go to bed at nine or it's nine o'clock, you want to go to bed at 10 and you go into the bathroom and you flip on the bright lights, your melatonin levels just got crushed down to zero. So having lights on is the worst thing you can do. Yes. And it doesn't matter if it's blue light, red light, purple light, green light. Bright lights inhibit melatonin very acutely.
Starting point is 00:06:10 And therefore, you want to avoid exposure to bright lights at night if your goal is to be asleep. So the simple rule that governs all this stuff is when you want to be alert, get bright light in your eyes, ideally from sunlight. So that's true in the morning and throughout the day. And when you want to be sleepy or asleep, avoid bright light in your eyes. Now, many home environments don't allow you to have zero lights, and that's not actually necessary. You can just dim the lights in the evening.
Starting point is 00:06:37 Ideally, you also avoid overhead lights because the neurons in the eye that trigger this melatonin suppression and so forth, they reside in an area of the eye that views upper visual space. So you could have desk lamps and just dim those down. If you're going to work on a screen, dim it way down. Will blue blockers help? Yes, but if the light is bright enough, you're still going to inhibit melatonin release. So how bad is watching TV at night? If the TV isn't too bright. If it's farther away.
Starting point is 00:07:08 Farther away. And maybe you wear blue blockers. I mean, some people take this to the extreme. They wear sunglasses. I think that's a little extreme. Now, candlelight and moonlight, surprisingly, doesn't seem to block melatonin. Now, maybe a really bright moonlit night, full
Starting point is 00:07:26 moon, the lunacy associated with the full moon might actually be due to a suppression of melatonin and an increase in alertness. So those are the things as it relates to light. Then there's this issue of people who have trouble staying asleep. So they can fall asleep fine, but they wake up at two or three in the morning. I happen to do this. If I go to bed around 10.30, I tend to wake up around three and I use the restroom. Yeah, I tend to drink a lot of fluids
Starting point is 00:07:53 and I have to use the restroom. This was true at every age. This is not just some aging related thing. That's fine. I just keep the lights dim and use the bathroom and then you go back to sleep. Fall back to sleep. Very normal, very healthy.
Starting point is 00:08:06 One of the best things I ever did for my sleep was to keep my phone out of the room so that when I wake up at 3 in the morning, I just didn't start scrolling the newspapers is typically what I'm doing online. Gotcha. And then you're just waking up your brain, not just by the light, but by the content. And, you know. You're activating it again as opposed to going back to sleep. Exactly. And sometimes there's a comment and they're like, is it you know your thinking is not very good in the middle of the night the other thing is you want to keep the room cool so in order to fall
Starting point is 00:08:31 asleep your body has to undergo a drop of in temperature of one to three degrees there are a couple ways to accomplish this one is keeping the room cool the other is to um and that's ideal actually because you can put a hand or a foot out. We actually lose a lot of our heat through what's called our glabrous skin. So the palms of our hands, the bottoms of the feet. I always put my feet out of the sheets and just let them feel the cool air. That's right. And that's a great way to cool off your core body temperature. You're probably doing that unconsciously in your sleep as well. If the room were too warm, the only way for you to cool off would be for you to put your hand
Starting point is 00:09:06 in a bucket of cold water, and generally people don't have that accessible. And then you're gonna go pee if you're doing that too. Right, exactly. And then of course there are all these products nowadays of things that cover, that cool the bed. I'm supposed to try one of these soon, I haven't tried one yet.
Starting point is 00:09:22 I tend to just keep the room cool. Cool, yeah. What do you keep it at? I keep it around 67, 65. That's a little cooler than what I do. I put it at about 67, 68. Okay. But I tend to wake up hot in the middle of the night, like throw the comforter off and go put some cold water on my face. So don't obsess over waking up too much. And if you do try and stay away from screens or if, um, you know, some people will read a book, dim light again, uh, and then falling back asleep. Some people are waking up at two or three because they are going to bed too late.
Starting point is 00:09:59 Their melatonin has run out. So imagine that you're naturally somebody who should go to bed early around nine, but we all have this ability to push forward and stay awake if we have to. Much easier to stay awake than to force yourself to go to sleep. Very hard to force yourself to go to sleep. So let's say your system, you start releasing melatonin around 9 p.m., but you stay up until 11. Then you get into bed, you fall asleep around 11.30, and at three in the morning, you suddenly wake up. Well, that's because your melatonin tapered off, and there's a wakefulness that's occurring.
Starting point is 00:10:34 And so ideally, you would start going to bed earlier. Now, there's a lot of discussion out there about so-called chronotypes. So night owls, morning people, people that follow a more typical schedule, typical would be going to sleep somewhere between 1030 and 1130, waking up somewhere between 630 and eight. Then there are the people that like to go to bed at 2am, sleep till 10. And then there are people that like to go to bed at eight and wake up at four. Huge variation out there. It tends to change across
Starting point is 00:11:02 the lifetime. Yeah. You're a season of life for years. That's right. And adolescents and teenagers tend to stay up later and want to sleep in. And there's actually some evidence that they can learn better if they are allowed to use that schedule, but most schools won't adhere to that schedule. You've got to wake up at six and go to school at eight or whatever. Yeah. Once you enter adult life, you're generally somebody who's going to have to learn how to go to bed early and wake up early, or at least wake up early. Now naps you should feel comfortable, the data say, naps you should feel comfortable napping
Starting point is 00:11:30 for 90 minutes or less at any point throughout the day, as long as it doesn't interfere with your nighttime sleep. So some people like me, I love naps, but it doesn't interfere with my nighttime sleep. It doesn't? Does not. So you take a 60-minute nap? Generally, 20 to 45 minutes.
Starting point is 00:11:49 And then you fully fall asleep, or you're kind of like awake and just resting? I can fall asleep anywhere, anytime. In like a minute? I can fall asleep in a gun range, yeah. What? Can you sleep sitting up too, like this? Oh, yeah. That's a gift.
Starting point is 00:12:02 Playing anywhere. That's a gift. It is, although it could reflect that I'm pushing my system a little too this. Oh yeah. That's a gift. Anywhere. That's a gift. It is, although it could reflect that I'm pushing my system a little too hard. Oh. But it is useful at times. Incredible, man. It is useful.
Starting point is 00:12:14 So you can fall asleep right on a plane or? Anywhere. Leaning against a, you know. Oh my gosh. In a subway station and anywhere. If I need sleep, I'm going down. That's incredible. Yeah.
Starting point is 00:12:23 So the other thing is that during sleep, a number of things happen. And we can talk about slow wave sleep and REM sleep. But one of the most important physiological functions of sleep is to clear out some of the cellular debris that accumulates throughout the day. The cellular debris creates cognitive deficits. It actually may be related to the aggregation of proteins and things that relate to dementia and Alzheimer's. It's the so-called glymphatic system. The lymphatic system is a system of moving through immune cells and clearing out of debris from the body. The glymphatic system is a kind of an equivalent system that exists in the brain that involves so-called glial cells, which are
Starting point is 00:13:05 support cells, but also do many things actively. They're not just doing support. The glymphatic system is like a washout of the brain's debris. And that system seems to function best when feet are slightly elevated above the brain. There's some interesting data from University of South Carolina coming out now that show that if you can get your ankles elevated a little bit higher than your chin, that's great. When you're sleeping? While you're sleeping. What's it do for you? It increases the glymphatic clearance. And there's some data that it can improve function of the brain. The studies that are happening now that I'm aware of, I'm in touch with that group, are mainly geared towards people that have had head injuries.
Starting point is 00:13:45 So concussion and TBI of various kinds. But they also are seeing interesting effects in typical folks that don't have any traumatic brain injury. So I put a pillow underneath my ankles when I fall asleep to get a little bit of that elevation. And then during the day, if ever you can't get a nap or you are going to get a nap, put your ankles up on the couch and lie down on the floor. That itself can get some of the clearance of the glymphatic system. And that helps you sleep better or it helps you just clean out the system? It helps your brain function better when you wake up from sleep. Interesting.
Starting point is 00:14:18 That's what the data are starting to show. That's cool. Some of the things I described, like the light viewing, is baked into the neuroscience literature, hundreds of papers, published papers. Some of the things like the glymphatic system is kind of cutting edge. It's on the way, but because the safety margins of raising your ankles are so large, I mean, there's nothing dangerous about that. How long do you need to do it for to get the benefits? Oh, I think these are immediate benefits. Two minutes or 10 minutes? But if you're doing this the whole night that you're asleep.
Starting point is 00:14:47 Your ankles are elevated. If you wake up and you happen to kick the pillow out, it's not the end of the world. But, but the idea is that you don't want to be sleeping with your head above your ankles either. There is some evidence that when people travel on planes and they're sleeping in chairs, that that's not equivalent to the kind of sleep they'd get when they're lying flat, independent of all the other things that are happening. And we know this because there are great sleep labs at Stanford School of Medicine, at UPenn, back east and elsewhere, where people actually go into a clinic and sleep either upright or at different angles.
Starting point is 00:15:17 And they track it. And they're looking at all this at the level of data. Okay. So here's one for you. What's the best position to sleep? on your back, on your side, on your stomach? Great question. And it really, truly depends. And it probably depends on how hot you run. So I tend to run really warm. A lot of the cooling of the body occurs from the palms and bottoms of the feet, but also from the upper back and scapulae because we accumulate what's called brown fat there. It's not the blubbery fat that's under the skin. It's like
Starting point is 00:15:48 a furnace. Actually, you can increase the density of brown fat by going into cold water repeatedly for one to three minutes several times each week. It means your furnace actually burns hotter. It allows you to be in cold temperatures more comfortably. Some really beautiful data just published on this. So I don't like to sleep on my back because I start heating up. Start sweating. That's right. So I tend to sleep on my side. I sleep in that, what is that? It's like soldier position. But then again, there are some people that have shoulder issues and then they can't do that. I'm relatively flexible through my shoulders, not super flexible. So I can do that. It really
Starting point is 00:16:23 depends. Now, of course, if you're sleeping on your stomach, how do you elevate your ankles? It starts becoming a little bit, we are not just science experiments. And so you have to assume that you're not gonna get everything exactly right. But keeping the room cool, keeping the cool being under a warm enough blanket,
Starting point is 00:16:43 but then extending a hand or an ankle out so that you could cool off during the middle of the night. That's going to be good. Keep the room dark, although complete pitch black doesn't seem to be as good as having a little bit of light somewhere in the room. But you don't want a bright blue light or red light anywhere in the room that's going to wake you up. Some people like me have very thin eyelids, exceedingly thin eyelids.
Starting point is 00:17:03 Some people have very thick eyelids. So some people are more bothered by a light in the room than others it really yeah so you have to just tune things to your particular environment I'm curious about the neuroscience before you go to sleep how do we set our minds up to you were saying before about a lot of people it's hard for them to sleep because they can't shut their mind off right is there something we should be thinking before we shut it off to set our sleep up for success mentally and then to really build into the next day where we wake up feeling like clear-minded and without this brain fog where we have more motivation,
Starting point is 00:17:39 where we have more energy and excitement towards the next day and then doing that in a pattern every night. Is there any science around that? Is it like listening to a hypnosis? That could be very helpful. Which will help you clean out whatever's going on through the day and get clear and ready for the next day, but also fall asleep so you're not thinking about it.
Starting point is 00:17:59 You know, is there anything that can help you have better dreams so that you sleep better? Like, what have you found there in the neuroscience? Yeah, so glad you asked this question. There's some really interesting data from a guy named Chuck Charles Zeisler, who is at Harvard Med. Sent beautiful studies on sleep in humans for many decades
Starting point is 00:18:17 and a really fantastic physician and researcher. And they observed something interesting, which is that about 90 minutes or so before your natural bedtime, there's a spike in alertness, planning, and almost anxiety that all people undergo, and it's a normal, healthy pattern. The idea, and it's a just-so story because we don't really know, I nor Chuck Zeisler nor anyone else was consulted that the design phase as we say but we assume this what this came about because prior to going to sleep we need to shore up everything for safety we need to you know lock things down make sure everything is in its place
Starting point is 00:18:56 because we were very vulnerable and nowadays this would might manifest as you know you're you need to go to bed at 1030 because you have to get up at 6 etc and then right around 830 or 9 you start finding yourself running around what might manifest as you need to go to bed at 10.30 because you have to get up at 6, et cetera. And then right around 8.30 or 9, you start finding yourself running around doing various things. Many people worry about that and they think, oh, I'm really stressed because I actually need to go to sleep and here I am wide awake. It tends to subside very quickly.
Starting point is 00:19:19 So just the knowledge that that's a normal, healthy spike in alertness and activity, I think can help a number of people. I want to make sure I mention that. Yeah. The other thing is preparing the mind, as you said, turning thoughts off. Turning thoughts off is a skill. We've talked before, gosh, almost a year or more now, ago, about Yoga Nidra. Yes.
Starting point is 00:19:40 Which is, there are many, many Yoga Nidra scripts available on YouTube free of cost. which is there are many, many Yoga Nidra scripts available on YouTube free of cost. The ones I particularly like are the ones by Kamini Desai. K-A-M-I-N-I-D-E-S-A-I. Kamini Desai. I just really like her voice. I don't know Kamini, never met her. These are free scripts. They're Yoga Nidra scripts that last about 20 minutes.
Starting point is 00:20:03 They involve some breathing, some meditation type stuff. but they teach you to turn your thoughts off which is really wonderful because a lot of people they just get stuck in this rumination now is there an ideal protocol prior to sleep it depends because some people find they have their greatest clarity after the kids are asleep and they're sitting there. So I wouldn't say don't work or do work. You know, you do want to avoid strong stimuli before sleep. So do you really want to watch, you know, a politically charged or a violent movie right before sleep? Well, that depends on how triggered you tend to be by politics or violence.
Starting point is 00:20:43 Some people aren't triggered. Other people are. But, you know, that aside, you don't want to go to bed either too hungry or too full because that can inhibit your sleep. So for most people, that's going to be finishing your last bite of food about two hours before bedtime. We used to think that aging was a one-way street. You couldn't do anything about it. We now know from studying twins that 80% of your health in old age is up to you,
Starting point is 00:21:15 how you live your life. Right. Your community, your positivity, your thinking, your food, the sleep you have, like all those things, right? Yeah. And the reason that they work, we've discovered, is because they turn on the longevity genes. That's the breakthrough. Okay. So now we're artificially tweaking these longevity genes genetically or with supplements or hopefully medicine soon. Gotcha. But you can do it in more natural, organic ways is what I'm hearing. Well, right now, that's what we've got. And even if you just do the five obvious things, things like skip meals and don't smoke and exercise, that'll get you an extra 14 years on average. Really? It's that big. That's not even using high tech. There's no technology,
Starting point is 00:21:56 just like living a good life. Right. So what are the main things to turning on the longevity that anyone can do without technology, without money, you know, science. Yeah. Well, okay. So we've, first of all, don't smoke. Yeah. That'll damage your DNA.
Starting point is 00:22:13 That'll accelerate the aging process. Does that include like e-cigarettes and all these other vaping? Does that also? Well, I'm a big advocate for putting nothing artificial in your body, including vaping. My mother died from lung cancer, so I'm pretty militant about it. Wow. I don't think vaping is as bad in terms of the number of chemicals getting into your body. Yeah.
Starting point is 00:22:39 But we've seen recently it's probably not healthy anyway. Yeah, yeah. Okay, so no smoking. That's one. That's one. Next one is don't eat so much. Eat less often. So not malnutrition, of course.
Starting point is 00:22:50 You don't want to get too thin. But this three meals a day plus snacks is ridiculous. It's been my life. In the future. You look great. I need to get rid of that. Yeah. Well, you're also working it out. But someone like me who's not an athlete, the most exercise I do during the day typically
Starting point is 00:23:04 is typing. Three meals a day is too much. Actually, one meal is enough for someone like me. Wow. Yeah, I'm now 50. So my metabolism is way down. You look like you're 37. Oh, thanks.
Starting point is 00:23:16 That's great, man. You might need glasses. I thought you were like 100 and you look like you're 37. You probably reversed the aging. Well, I'm glad I don't look 80 because that would really be bad for my message. Okay, so we got no smoking, eating less. Yeah.
Starting point is 00:23:32 Next one would be the obvious, high intensity interval training. Lose your breath once in a while. Lose your breath? What do you mean? Just by like working out? Yeah, become hypoxic. Tell your body that
Starting point is 00:23:44 you're being chased by a saber-toothed tiger or something like that the reason all of this stuff works in terms of the diet and exercise uh it's not that your blood flows more or that being hungry is is just healthy for the body it's actually that your longevity genes get turned on by these things and why does that happen why does it happen in humans in mice even in yeast cells for bread and beer? The reason is that the body senses adversity and says, crap, we got to fight back. We might die next week without food. And we're running away from tigers and lions. That's what this survival network, this longevity gene- So it turns it on when it feels like it's in survival mode. That's it. feels like it's in survival mode.
Starting point is 00:24:25 That's it. We want to be in survival mode. And we spend our whole lives trying to reduce our adversity. Right. Being comfortable. Right. Don't be hungry. Don't be puffed.
Starting point is 00:24:37 Don't walk. You know, valet your car. Right. Roll your suitcase. Don't carry it, for goodness sakes. We've done the worst no wonder we're getting sicker and sicker we're in a world of convenience right and it's the worst thing we could do really for our bodies in terms of longevity so those three things okay uh the other
Starting point is 00:24:56 two um uh let's see what else is there oh the type of food you eat is important uh yeah there's a big debate of course. Let's say like plant-based is going to extend the telomeres, right? If you're eating leafy greens, that's what I've heard. Right. Well, among other things, it's also going to have a couple of really important types of molecules. One are the monounsaturated fats, fatty acids. You get that from olive oil and avocados.
Starting point is 00:25:24 Those are great and uh we've just learned that that's a really important trigger for a certain longevity olive oil yeah i think uh when i had gundry on he was like i drink a cup of olive oil a day or something like teaspoons of olive oil he's just eating it well he's like i'm trying to get as much in as i can putting it on everything yeah well let's get back to that because there's a new discovery as of a week ago that says we think we understand how that works. But in olive oil, there's also what are called, the other important component of a plant-based diet are polyphenols, which are the molecules that plants make when they're under adversity,
Starting point is 00:26:02 when they're stressed. And i believe that we've evolved to sense when our food is running out so we get that signal when our plants are stressed so you don't want to eat plants that are like this white white liquid lettuce you can buy californian lettuce right right you want these colored vegetables that have been a little bit stressed a little bit dried out wine is a perfect example it's full of polyphenols, one called resveratrol that we've worked on for 20 years. And it activates these longevity pathways really well. So stress your food, organic. I am for a plant-based diet, but I do eat meat occasionally.
Starting point is 00:26:37 It tastes pretty good. But it's very clear, Dan Buten is right, where you go to the longest-lived places in the world. The blue zones, right? Sardinia, right? The Okinawa Island in Japan. They're not eating all meat. And actually, we know that if you eat a lot of meat, you shut down some of these longevity pathways.
Starting point is 00:26:56 Really? Yeah. So you actually, you might look good and grow muscle. And that's great when you're young. You want to find a mate. You want to look good. You want to feel good. But in the long run, I don't think that's healthy.
Starting point is 00:27:06 Really? So cutting down less and less meat, at least, having more plants is the way to go. Yeah, that's what I've done. I was on an Okinawa diet in my 20s and 30s. Which is what? There's rice and leaves? It's a bitter rice. You've got to watch out for white rice because it'll spike your sugar.
Starting point is 00:27:23 Yeah, it's a lot. But it's a lot of tofu, miso soup uh green leafy vegetables dark greens for these phytochemicals and then what else was it there was a bit of fish okay yeah but but also what's important is not a lot of food on these days i'm stopping eating when i'm about 60 70 percent full and i'm trying to just never feel full until i'm like eating so much and then I'm like, okay, I'm full. Well, you're a young, active, hungry man. Well, here's one of the things. I think one, when you eat slower, you start to get fuller.
Starting point is 00:27:55 You start to feel it. And I'm the youngest of four. And so as a kid, we didn't have a lot of money growing up in a small town in Ohio. And there wasn't that much food. So I learned to like grab and just shove it in my mouth. And that became a habit that I've kind of stuck with. And I'm not starving anymore. Like the food's available at any time.
Starting point is 00:28:13 I can afford it. And I have it all the time. But I think it's reconditioning my mind or a habit or routine of like, I'm not scarfing my face down right now, but you know, it's that's that mindset of, what if I'm going to go hungry? For sure. We all suffer from that. Well, not all of us, but those of us who grew up in regular families, we were told to finish our meals.
Starting point is 00:28:33 Right. Don't leave anything on the plate. There's hungry kids everywhere. And if you've got problems, brothers and sisters, right? They're stealing your food. My wife grew up in a very poor family. And even when she was a student, she could barely afford food. She would scrounge and buy potatoes.
Starting point is 00:28:48 And at the dinner table, she'll kill me for this, but she will eat like it's going to all go away tomorrow. But I have to remind her and everybody, everyone should know this. There's always going to be another meal. There will be another meal. Don't worry.
Starting point is 00:29:03 But we're conditioned to eat food when it's in front of us. I think it's a mental conditioning. And it's also like, either your body's tricking you or it's your brain or it's your gut or something is tricking you, like, I'm still hungry. Even though you had 2000 calories in 10 minutes, you're still like, oh, there's food. It's like turning something on. You're like, I want to eat that. I don't know why that is. Well, yeah. I mean, it's the reason that we're here. Our ancestors put on fat and they survived the famine.
Starting point is 00:29:31 We don't have famines anymore. Thank goodness. But we've descended from those people. So we've got the genes in our brain that say, eat, eat, eat. How do you turn that gene off? Well, you can take certain types of food. I drink a lot of tea and coffee, hot water even, just to fill up my stomach. That works really well.
Starting point is 00:29:52 Okay. Hot water, not cold water. I just like the feeling of hot water. Cold water isn't as – actually, it might be something about the heat. I've never thought about it, but for me, that's what works. So when I get a little bit hungry at lunchtime, I'm basically, I'm basically drinking tea. Warm water tea. Yeah. You put it like some. Yeah. Interesting. But it's a fight all the time. Yeah. You know, I fly a lot and people are bringing nuts and cookies and ice cream and you got to fight it. And it's really hard
Starting point is 00:30:19 to fight. How do you say no? Well, I do. But how do I do that? So I've trained myself to fight it. And the best thing that I do besides saying, can I have a cup of tea, is what do I want to look like next week? What do I want to look like a year from now? What do I want to look like when I'm 80? So you tell yourself that. You ask yourself the question. I think it's also how do you want to feel tonight, tomorrow, next week when you're 80? It's like look like and feel combination is powerful. Right. Because your mind is saying
Starting point is 00:30:50 now is important and you've got to train yourself to say tomorrow and the next year is just as important. Right. And that's more important. Okay. So was that the fourth thing or the fifth thing? The fifth thing I didn't mention. There are a couple of things. Let's divide it up. One is get good night's sleep. Sleep is everything. Yeah. And then surround yourself by friends and people who will take care of you. Yeah.
Starting point is 00:31:11 That's like the blue zone way too, right? It's like be around a good community, get lots of rest and naps, move a little bit, eat healthy. Right? Well, these are things that most people should know, but they don't do. So you and I are here to most people should know but they don't do so you and i are here to motivate people to do that exactly but the research that i discuss in the book is how to take that to a new level how to optimize those things and add some science in there sleep is probably the single most effective thing that you can do to reset both your brain, but also your body health, of course, as well.
Starting point is 00:31:47 And I don't say that flippantly against the notions of diet and exercise. Of course, both of those are fundamentally critical. But if I were to take you, Lewis, and I were to deprive you of sleep for 24 hours, deprive you of food for 24 hours, or deprive you of even water or exercise for 24 hours, deprive you of food for 24 hours, or deprive you of even water or exercise for 24 hours. And then I were to map the brain and body impairment that you would suffer after each one of those four. Hands down by a country mile, a lack of sleep will implode your brain and body far more significantly. The only one I would probably lose out on is oxygen. At that point, I'll give it up. You know, sleep will take the silver medal. Oxygen definitely
Starting point is 00:32:32 gets the gold. But thereafter, sleep seems to be paramount. Over sleep, food and water, sleep is the most important thing. I would say, yeah, you know, I used to say that sleep was the third pillar of good health alongside diet and exercise. But I think the evidence has suggested that I was utterly wrong. That sleep, in fact, is the foundation on which those two other things sit. And you can do wonderful things in those two domains. But if you're not getting sufficient sleep, those things tend to be far more futile as a consequence. And so what is sufficient sleep then?
Starting point is 00:33:09 So right now we recommend somewhere between seven to nine hours for the average adult. Once we know that you go below seven hours of sleep, we can start to measure objective impairments in your brain and your body. And in fact, the number of people who can survive on less than six hours of sleep without showing any impairment rounded to a whole number and expressed as a percent of the population is zero. Without any impairment, what does that mean? So if I can measure lots of different operations of your brain, let's say your cognition, your attention, your learning and memory, also your moods and your emotions and your anxiety or downstairs in the body, I can measure aspects of your cardiovascular system or your blood
Starting point is 00:33:56 pressure, or I could measure your immune system or your metabolic system, how it's regulating your blood sugar and your glucose. or your metabolic system, how it's regulating your blood sugar and your glucose, I can measure this sort of pinwheel, this kaleidoscope of health metrics on Lewis Howes. And then I can see when I keep dialing you back with less and less sleep, at what point do I see at least one of those things demonstrating a breaking point? And it's very rare for us to be able to find any individual who can go below six hours of sleep and not show some kind of impairment. And a great, even frightening demonstration of this, a study took a group of perfectly healthy individuals, and they limited
Starting point is 00:34:39 them to six hours of sleep a night for one week. And then they measured the change in their gene activity profile relative to when those same individuals were getting a full eight-hour night of sleep. And what happened? And there were two critical findings. The first was that a sizable and significant 711 genes were distorted in their activity caused by that one week of short sleep. And that's, you know, in some ways, I think about this, Lewis, because it's reality. We know that almost a third of the population is trying to survive on six hours of sleep or less. So it's not just, you know, total sleep deprivation, which doesn't happen very frequently. It's a common occurrence. What I found most interesting was that about half of those genes were actually increased in their
Starting point is 00:35:26 activity the other half were decreased now those genes that were suppressed were genes associated with your immune system so you became immune compromised or immune deficient those genes that were increased in their activity or what we call overexpressed, were genes associated with the promotion of tumors, genes that were associated with cardiovascular disease and stress, and genes that were associated with long-term chronic inflammation within the body. And I make that point just because, you know, many people, I think, have this concern about things such as genetically modified embryos or even genetically modified food. But when we don't get sufficient sleep, we are unwittingly performing a genetic manipulation on ourselves. You know, if we don't let our kids get the sleep that they need,
Starting point is 00:36:17 then we're inflicting a similar genetic engineering experiment on them as well. Wow. This is crazy. So what if you've been sleeping less than six hours a night for years? What is that saying to your genes? And is there a way to recover the gene damage and reverse and go back to a healthy genes, healthy body, healthy life? So firstly, we know that short sleep duration. using that sweet spot and we can speak about oversleeping or excess sleep because that i think that's an interesting part that hasn't been spoken about too much but using that recommended cdc amount of seven to nine hours of sleep there is a simple fact firstly across the lifespan which is the shorter your sleep, the shorter your life. That short sleep predicts
Starting point is 00:37:05 all-cause mortality. But then we can dig a little bit deeper and start to sort of ask, you know, exactly what is going on? Why is there such mortality risk caused by insufficient sleep? And what we know is that a lack of sleep, and typically getting certainly less than six hours of sleep, is associated with a higher risk of cardiovascular disease, high risk of diabetes, high risk of stroke, high risk of dementia. And I would love to double click on that and go into the Alzheimer's disease risk because that now evidence is very, very strong. And then downstairs in the body, we know that there is links between a lack of sleep and certain forms of cancer. After, if I were to take you and limit you to, let's say, four or five hours of sleep for one week,
Starting point is 00:37:50 your blood sugar levels would be so disrupted that your doctor would classify you as being pre-diabetic. Oh, my goodness. So that's not a lifetime. That's just one week. And there's an even more interesting experiment that I think speaks to the subtlety of this. Because there is the largest sleep study that's ever been conducted. And it happens actually to around 1.6 billion people across 70 countries twice a year.
Starting point is 00:38:18 And it's called Daylight Savings Time. Now, in the spring, when we lose just one hour of sleep opportunity, now in the spring when we lose just one hour of sleep opportunity firstly what we've seen is that there seems to be a 24 increase in relative heart attack risk the next day which stuns me um and what's fascinating in the fall in the autumn when we gain an hour of sleep there's a 21 reduction in heart attacks so it's bi-directional and that's just one hour of sleep. And you see, there was some great recent data. You see a very similar profile regarding that daylight savings shift for road traffic accidents on our streets. I've heard about this. Tragically, suicide rates as well. And then even more recently, what we discovered is that
Starting point is 00:39:06 rates as well. And then even more recently, what we discovered is that during that spring time shift, when you lose an hour of sleep, the sentencing of federal judges is significantly harsher because their mood and their emotion is that much worse because of that one hour of sleep that they dole out harsher sentences. So, you know, we can walk, you know, you can ask the question, what about a lifetime? We don't even have to ask about a lifetime of short sleep. We can ask about these really, you know, one week of short sleep or even one night of one hour of lost sleep. And I think that's how fragile our brains and our bodies are to this thing called a lack of sleep. And you could then ask, well, you know, why are we so sensitive? Because I can go without food for 24 hours and I can go without water for 24 hours. You know, I'm still not too bad. I'm in
Starting point is 00:39:57 fairly decent shape. Why is sleep the exception to that rule? And the answer seems to be this. is sleep the exception to that rule? And the answer seems to be this. Human beings are the only species that will deliberately deprive themselves of sleep for no apparent good reason. Why is that? And it was such a unique thing. And what that means is that mother nature, through the course of evolution, because no other species does this without real need for survival. And I can speak about some of the exceptions, but human beings are strange like this. In other words, mother nature hasn't have to face the challenge of coming up with a solution called sleep deprivation because she's never faced it in the course of evolution. And so there is no safety net in place here. And that's why we think human beings implode so quickly and thoroughly,
Starting point is 00:40:47 mentally, cognitively, and physically caused by insufficient sleep. And why do you think, why is the majority of people bad at getting good sleep? Is it, what is it? We're distracted? Is it, we think we need to be doing more? Is it, we're stressed and worried about the past and the future? Is it, you know, what, we just want to work harder? What is the main cause of why we get poor sleep? That's such a fundamental question. And in some ways, it's all of the above plus. So I think the first, and I've thought about this a great deal,
Starting point is 00:41:22 why are we suffering this global sleep loss epidemic that we're under right now? I think the first thing is that unfortunately sleep has an image problem. That, you know, the PR agent for sleep should be fired because we associate sufficient sleep with this concept of being lazy, of being slothful. And that's a terrible disservice to this thing called sleep. And it is very different to things like diet and exercise. You know, I think a lot of people like to virtue signal with, you know, what they eat. And they certainly are very proud to tell you,
Starting point is 00:42:00 you know, I work out five times a week. I'm in the gym at this time of morning. And, you know, all of which I think are great and to be applauded and supported. But we have the very opposite. We have this almost, you know, well, we don't. Some niches of society have this sleep machismo attitude. You know, this kind of you can sleep when you're dead mentality, which which by the way, based on the evidence is mortally unwise. Yeah. It will lead to both a shorter life and a life that is significantly less healthy. So I think the first thing is we need to change our cultural
Starting point is 00:42:36 appreciation of sleep from something that is a waste of time to something that in fact is an incredible investment. It is probably the very best and the most freely available democratic and painless health insurance policy that I could ever imagine. I think the next thing is the way that we work in society. We are working for longer hours and before the pandemic, people were commuting increasingly longer amounts of time. What that meant was that people were leaving the house earlier. They were arriving home later. And no one wants to shortchange time with family or Netflix or whatever it is you're poison.
Starting point is 00:43:21 And so the one thing that has become squeezed like vice grips in the middle of the night is this thing called a sufficient bout of slumber. But then there are plenty of people who give themselves the opportunity to get enough sleep, but they can't obtain it. And that is where things such as insomnia or sleep disorders, things like snoring come into play. And you touch up, and I know that you've spoken, and I'm so grateful for what you've done regarding discussions of mental health. We know that one of the principal roadblocks to getting this thing called a good night of sleep is anxiety. Stress, worry, anxiety, regret, all those things. Resentment, holding on to all that stuff that stuff it is that is toxic to sleep you're absolutely right and in fact anxiety and physiological stress is our principal model for the explanation of insomnia right now it's not the only cause
Starting point is 00:44:20 but it seems to be one of the principal causes. And in modern society, it's become so easy and I'm not finger wagging. I, you know, I'm just as guilty. We are constantly on reception, but rarely do we do reflection. And unfortunately the time when most of us do reflection is when we turn off the light and our head hits the pillow. And that's the last time. Oh, you know, because I don't know about you, Lewis, but, you know, at night in the dark, thoughts are not the same thing. You know, concerns become twice as big, 10x the size of concerns. I start to worry, I ruminate, I catastrophize. Yet in the light of day, those things seem very different. And so we can speak about sleep tips perhaps later on, but certainly getting right with your emotions and your anxiety is key to good sleep. And that's one of the things
Starting point is 00:45:20 that prevents sleep. I also think that there is an issue at the public health level. You know, we've had in many first world nations, wonderful government mandates regarding health, regarding drink driving, regarding, you know, safe sex, regarding drugs and alcohol and even food and even inactivity and sitting. And when was the last time you heard of a first world nation provide a public health message and memorandum regarding sleep? Never. And I don't remember one either. So from every level at, you know, at a public health,
Starting point is 00:46:01 global, you know, government level down to a workplace level, you know, at a public health global, you know, government level down to a workplace level, you know, we lured the airport warrior who's flown through four different time zones in the past three days. They were on email at two and then they're back in the office at six, you know, so we need to... We celebrated those people. We did, you know, and the funny thing, by the way, is that after about 20 hours of being awake straight, you are as cognitively impaired as you would be if you were legally drunk. Now, I would never, you know, as a CEO say, I have got this fantastic team of people that are drunk all of the time.
Starting point is 00:46:40 But we do say, I've got this fantastic group of people. They just are at it all hours. They are dedicated. They're always working. You know, they spend minimal time sleeping. They're just all out. They love this project, but we've got this strange mentality.
Starting point is 00:46:56 And then I think it comes down to, you know, even within schools, we've got this incessant model of early school start times. And super early, isn't it? It's, it's incredible. You know, even within schools, we've got this incessant model of early school start times. And... Super early, isn't it? It's incredible. We've got to be there, what, 6.30 or 7 or something, right?
Starting point is 00:47:10 6.30, 7, 7.30. And that data is actually very powerful. What we found is that when we delay school start times, first academic grades increase. Wow. Truancy rates decrease. Psychological and psychiatric issues decrease but then what we also discovered is that the life expectancy of students increased and you may be thinking well hang on a sec you know how do you how do you measure that and the leading cause of death
Starting point is 00:47:42 in teenagers 16 to 18 is actually not suicide. That's second. It's road traffic accidents. Really? And here, sleep matters enormously. And I'll give you one example. It was in Teton County in Wyoming. They delayed their school start times from 7.30 in the morning to 8.55.
Starting point is 00:48:04 By the way, what are we doing trying to educate our children at 7.30 in the morning to 8.55. By the way, what are we doing trying to educate our children at 7.30 in the morning? No, I can't think. Yeah, I mean, I remember being in school and being every day was hard for me. Every day I was tired. Every day it was hard to focus or I'd be irritable or wanted to like jittery or something, but it was like so hard to. And then you're at lunchtime, and then I eat, and I'm tired again afterwards, and you want me to focus and pay attention at a desk. It doesn't work like that for me, especially on no sleep or very little. Well, for any developing brain, it doesn't work like that. And for some people, to make a 7.30 a.m. start time, school buses will begin leaving at 6 o'clock or 5.30
Starting point is 00:48:48 in the morning. That means that some kids are having to wake up at 5, 5.15. This is lunacy. And what we've understood from the academic grades, and I'll come back to the car accidents in a second, when sleep is abundant, minds flourish. And when it's not, they don't. And what we've discovered with the road traffic accidents in Tenton County, when they made that shift, the only thing more remarkable than the extra one hour of sleep that those kids reported getting was the reduction in car crashes. The following year, there was a 70% drop in vehicle accidents. Wow. And to put that in context, you know, the advent of ABS technology, anti-lock brake systems,
Starting point is 00:49:32 that dropped accident rates by 20 to 25% and it was deemed a revolution. Here is the simple fact of getting enough sleep that will drop accident rates by 70%. So, enough sleep that will drop accident rates by 70%. So, you know, I need to get off my soapbox. But what I would say is this, I think if our goal as educators is to educate and not risk lives in the process, then we are failing our children in the most spectacular manner with this incessant model of early school start times. Is anyone listening to this that you've been speaking about this too, and they're actually adopting this new model, whether it be work time or school time or just integrating this? Do you know systems that are integrating this?
Starting point is 00:50:15 There have been some, and I think I've tried to do this in the education domain. I've tried to do this within medicine because the way that we train residents is almost inhumane. Actually, it's not almost, it absolutely is inhumane. And the statistics there are stunning as well. And then I've tried to do it in the workplace too, because I do a lot of speaking events at sort of Fortune 500 companies. And at first, I think I took the wrong approach where I was really speaking a little bit more about sort of the compassionate approach, you know, why it's good and kind for people to gift them more sleep.
Starting point is 00:50:54 Because I see sleep as a biological necessity. And if it's a biological necessity, then I think it's a civil necessity. And if it's a civil necessity, sleep is a civil right. But what I would say is that that wasn't particularly well received. You know, I'd go into business companies and say, your employees, you know, they're desperate for more sleep. They will be happier and healthier. Or I would speak about medicine and I would speak about, you know, what it was doing to the patients and the harm. And it would fall on deaf ears.
Starting point is 00:51:29 What I then realized is that if you're going to change large organizations, you have to speak in their currency, which is money. Yeah, you need to. And then I would describe the medical malpractice lawsuits that would commonly cost savings within medicine, firstly. And then administration started to change the tune. Because before that, you know, there was almost this old boys network in medicine where we went through residency, and it's almost a hazing. And despite armed with incredible data to the contrary, I think the mentality 10 years ago when I started trying to do that was, my mind's made up, don't confuse me with the evidence.
Starting point is 00:52:11 Crazy. Why? It's because they went through that themselves and so they want to pay it back or something. I think so. I think there was some of that. I went through hell, so everyone else has to go through hell, yeah.
Starting point is 00:52:20 Right. It's a rite of passage. If you are tough enough, you'll make it through. It's kind of like bootcamp, which I don't think we need to do anymore. And then within business, you could describe, you know, the Rand Corporation did an independent survey a couple of years ago. And what they found was that insufficient sleep will cost most nations about 2% of their GDP of their gross domestic product. about 2% of their GDP of their gross domestic product. So here in the US, that number was $411 billion of lost productivity due to insufficient sleep. In Japan, it was $130 billion. My home country, the UK, it was over $50 billion.
Starting point is 00:52:56 So if I could solve the sleep loss crisis within the workplace, I could almost double the budget for education in the US or I could halve the healthcare deficit. So when you speak about money, then people start to listen. So that's how I've tried to communicate. And I don't think I'm a particularly good communicator. And I've been sometimes bull in a china shop, as I probably have for the first uh however long we've been uh talking but it's just because I'm so you know I'm just desperately passionate about this thing called
Starting point is 00:53:30 sleep and some years ago before I started trying to I wrote a book and then I've been doing podcasts sleep was the neglected step sister in the health conversation of today. It was a second citizen. And I was so sad to see the disease, the sickness, the harm, the lack of productivity, the impact on education that a lack of sleep was having. I hope you enjoyed today's episode and it inspired you on your journey towards greatness. Make sure to check out the show notes in the description for a full rundown of today's episode with all the important links. And I want to remind you, if no one has told you lately that you are loved, you are worthy, and you matter. And now it's time to go out there and do something great.

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