The Ultimate Human with Gary Brecka - 267. Dr. Clay Moss: On Metabolic Health, Insulin Resistance, Peptides, & Sleep Hygiene

Episode Date: May 5, 2026

The number one side effect of comfort is chronic disease, and we’re more comfortable than any generation in human history. In this episode, Dr. Clay Moss and I unpack the simple, foundational shifts... that produced life-changing results in a 7-day in-patient metabolic rehabilitation protocol: full elimination diet, sleep hygiene, intentional movement, stress management, and community connection. No biohacking gadgets required. Just a return to the basics, your biology was built for. CLICK HERE TO BECOME GARY’S VIP!: https://bit.ly/4ai0Xwg Listen to "Off Label with Dr. Clay Moss" on all your favorite platforms! YouTube: https://bit.ly/4defyfj  Spotify: https://bit.ly/4t5CbY7  Connect with Dr. Clay Moss Website: https://bit.ly/4cGbCE7  YouTube: https://bit.ly/423HwEo  Instagram: https://bit.ly/4mZqjoZ  Facebook: https://bit.ly/4teExEk  TikTok: https://bit.ly/423KkkU  X: https://bit.ly/3R88atg  LinkedIn: https://bit.ly/4cVVAVx  Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij  AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD  AIRES: "ULTIMATE20 " FOR 20% OFF: https://bit.ly/4a3Duze  BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa  BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV  COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp  CYMBIOTIKA: "ULTIMATE10" FOR 10% OFF: https://bit.ly/4tjyluP  GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk  GENETIC TEST (USA ONLY): ⁠https://bit.ly/3Yg1Uk9  GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC   H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg  HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S  PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn  SNOOZE: LET’S GET TO SLEEP!: https://bit.ly/4pt1T6V  WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW  Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 ​Intro of Show 04:18 Metabolic Syndrome Definition 06:00 Dr. Clay Moss’s Medical Journey 16:05 Biomarkers to Start 23:14 Functional Medicine Program 28:25 Stress Management Protocols 21:35 GLP-1: Pros and Cons 37:21 Future of Peptides 41:42 When Should People Take Peptides, GLP-1? 47:54 Muscle as Our Metabolic Currency 53:14 Female Hormone Therapy Benefits 58:04 Dr. Clay Moss’s Mission-Vision 1:03:38 How to Improve Sleep Hygiene 1:08:08 Connect with Dr. Moss 1:08:40 What does it mean to you to be an Ultimate Human? Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript
Discussion (0)
Starting point is 00:00:00 I think a lot of people relate aesthetic health to metabolic health. You can go years and years and have chronic disease even though he looked good in the mirror. You talk about how the most dangerous drug right now is comfort. And the number one side effect of comfort is chronic disease. We live in a society where everything is becoming more comfortable to us, and yet we're getting sicker as a society, and I don't think that's coincidence. When we talk about the basics to people about how impactful things like movement, stress management, community, connection, and how food is medicine,
Starting point is 00:00:27 They almost want to refute that because it seems like it's too easy. There's so many things that we're living with in this unnatural world nowadays that if we just kind of get back to our roots a little bit, we can fix things one by one. Can you talk a little bit about the importance of strength training muscle beyond just what we see in the mirror and why you think muscle is medicine? To me, muscle is the root of... Hey guys, welcome back to the Ultimate Human podcast. Today I want to introduce you to someone who is redefining what it means to ask.
Starting point is 00:01:09 actually prevent disease. Dr. Clay Moss is a functional medicine physician who looked shredded in the mirror and was metabolically falling apart on the inside. He had strep throat 22 times in four years of college. His labs told a story his reflection never could. And that personal reckoning sent him on a mission to expose a hard truth. What looks healthy and what is healthy are two completely different things. In this conversation, we're going to go deep on fasting insulin, a biomarker that can predict disease five years before your doctor catches it. We're covering why strength training reduces mortality risk by 200 to 400 percent more than any other drug ever created, and we're blowing the lid off the insurance system that is actively preventing you from getting the care you need.
Starting point is 00:01:54 If you care about living longer, not just looking good, don't skip this one. Hey guys, welcome back to the Ultimate Human Podcast. I'm your host, human biologist Gary Brecker, where we go down the road of everything, anti-aging, biohacking, longevity, and everything in between. And I am so fired up for today's podcast because in the clinical world today, you have traditionally trained physicians that are sometimes and for some reason, maybe a major life event, maybe curiosity, maybe it was because they had to solve a problem for a patient or something in their own life, or transitioning now to the functional medicine side, the root cause medicine. And today's guest is absolutely in that category. I'm a
Starting point is 00:02:38 huge fan. We just did a whole podcast before we did the podcast walking around the house. But welcome to the podcast, Dr. Clay Moss. Yeah, man. Thank you for having me. I've been a big fan for a long time. And let's see if we still have some content left in us after all that. Yeah. I said this is going to be like one of the easiest podcasts I've ever done because when I get people on the podcast like you and I'm blessed enough to have, you know, real functional practitioners, especially those that have, I talk about this crossover from allopathic medicine, but it's an integration of alopathic medicine and functional diagnostics. You know, it's, I'm, I'm just such a curious person, and I'm curious on behalf of my audience, so I'm really pumped to run this
Starting point is 00:03:18 for you today. Yeah, ma'am. You know, I notice in, in, in your work and in watching a lot of the podcasts that, that you've done, you know, you talk a lot about metabolic health. And, and when I started when I accepted the chairmanship of the Maha action, Bobby Kennedy's Maha action, one of the things that astounded me was when we look at big data and you look at 85% of chronic disease, which is where the majority of our spending, our $5 trillion in spending annually is going towards chronic disease. And you look at the spending on potentially preventable chronic disease, one of the things that constantly comes up is metabolic health and metabolic syndrome. And I wonder if a lot of people really understand what that means. Like when you say
Starting point is 00:04:11 metabolic syndrome to an average person, I think it sort of flies over their head. Right. So can you describe what metabolic syndrome is and what it means to be metabolically sick or metabolically healthy? So I think the easiest way to describe that is the root cause of pretty much all chronic disease starts with your metabolism and your metabolic health. And what that is, at least in my eyes, the way I explain it to people is the first thing you usually see in that is insulin resistance. So, you know, if we're eating ultra-processed food, high-carb diets, things that we really didn't used to eat back in the day, we're constantly flooding our body with insulin that we have at very high levels that we didn't used to have. And that causes a whole slew
Starting point is 00:04:49 of diseases that we're seeing rise at astronomical rates in a country that is more technologically advanced than it's ever been. Yeah. It's crazy because we're going up in so many categories. and yet down in our health for the first time in history. And the first time we've had a reversal in life expectancy in our recorded history was last year. You know, meaning like technically speaking, your children and my children have a shorter life expectancy than we do, statistically speaking.
Starting point is 00:05:18 So it's frightening. So metabolic health begins with, or metabolic disease begins with insulin resistance. You know, and I am of the school that insulin resistance and high glycemic profiles are like the root of all evil. Right. When you look at like, you know, what are some of the first dominoes to fall in this whole consequential series of conditions? If I was to only pick one, and there's, it's multifactorial, but if I was to only pick one, I would, I would agree that insulin resistance. Yeah, and I even started to see this in myself when I was in college.
Starting point is 00:05:59 So I grew up kind of with a human performance lens on medicine. I actually was born and raised in the panhandle of Florida, the Andrews Institute, which at the time and still is to an extent the mecca of sports medicine moved to my hometown. And so I'd be walking home from school and see these amazing athletes that you would only see on documentaries or live in games, you know, walking by my high school or I would walk home and see them kind of through the through the gate a little bit from the other side. And so I always grew up with this vision of human performance and how do I get there in the School of Medicine. How do I become a physician and work in that avenue? And when I got into college, I had a complete identity crisis. I didn't know anybody in college.
Starting point is 00:06:44 I started having panic attacks. I really didn't know who I was anymore. You know, I grew up in the same hometown. I knew who I was. I was an athlete. Everybody knew me. I knew everybody. And then you go to somewhere new and you're out of your element.
Starting point is 00:06:55 You don't play sports anymore. Yeah. You know, you're trying to socialize. People don't know who you are. And I fell in love with weightlifting, and that just kind of became my... Yeah, you're pretty jacked. I mean, I don't have a lot of people more jacked to me on the podcast, but can we actually take him down a few notches?
Starting point is 00:07:13 Right. Yeah, well, AI edit this. Yeah, yeah, the little AI edit. But the point I'm trying to make, though, is that I was still not taking care of myself from a baseline level. So even though I got so into weightlifting. in athletics and quote unquote aesthetic health, I had strep throat 22 times within four years
Starting point is 00:07:33 while I was in college. Wow. So I was pretty much going to the doctor or the urgent care once every two months, getting diagnosed with strep, giving antibiotics, getting a shot of steroids, and then being sent on my way, only to come back two months later
Starting point is 00:07:45 and nobody asked about my sleep, my caffeine intake, what I was eating on a daily basis, the last, you know, how close to bedtime am I eating, how many days a week in my training? I was training seven days a week. I'm having pre-workout at 5 p.m. But I looked good in the mirror. And so I just assumed like if I look good in the mirror,
Starting point is 00:08:06 then this all has to be happening to me, not because of me or something that I'm doing. And so I think a lot of people relate aesthetic health to metabolic health. And I've come to realize that the mirror is a really poor judge of what's inside. And so we're trying to chase both aesthetics because I do think there is some power.
Starting point is 00:08:24 behind looking good and feeling good, but also what's on the inside, too, because you can go years and years and have chronic disease even though he looked good in the mirror. Yeah, I totally agree with that. And so when was there like a eureka moment, was an aha moment, or was it sort of this slow transition from traditional alopathic medicine to really wanting to be back at the root cause of medicine? Like what was the, because you've really gone deep down the rabbit hole of, peptides and functional medicine and, you know, what I would call, you know, this new, you know,
Starting point is 00:09:03 surge in interest in longevity and anti-aging and bio-optimization and not just living but thriving. Right. Was there like a single aha moment or is this something that sort of evolved while you were in your medical training and you said, I would really want to, you know, open my eyes to peptides and some of these other modalities that are available and not outside of the traditional allopathogram. Yeah, I think it started when I was a patient back then. I think I developed somewhat of a hatred
Starting point is 00:09:34 towards the medical system while I was trying to chase to become a physician. Because I was just constantly being put through the ringer. I had strep 22 times in those four years. I was convinced to get my tonsils out. I got my tonsils out. I got strep six weeks after getting my tonsils out when they told me that wasn't possible.
Starting point is 00:09:51 I was convinced to get sinus surgery, because I literally couldn't hear my professors. I would call my parents in tears, like trying to study for the MCAT. So many things just gave me a little bit more of a deep dive into what patients actually go through when they are being let down by the medical system. And so I went into medical school.
Starting point is 00:10:08 I thought that I was going to do surgery because that was the only lens that I had seen human performance through when I was young. I just thought all orthopedic surgeons, like that's what I'll do and that's the only avenue to get there. And COVID hit during,
Starting point is 00:10:21 towards the end of my first year of medical school, school. We all went home. I ended up getting a job at the Institute for Human and Machine Cognition. So I was working with like these really cool. Human and machine cognition. Yeah. So I was doing some DARPA funded projects for Special Forces guys. And so I pretty much got to like be in the sun and play with AR-15s the entire summer. That's cool. Over COVID summer. And I, it's funny because I was outside all the time. I got to go home. I got to actually like stay grounded. I came back to school so much healthier than I was before. And, and then I went right into kind of the second half of the didactic learning and the clinicals. And what I learned was, I want to go back. I want to go back
Starting point is 00:11:02 to the human performance stuff. Like, how do I get a medical profession that allows me to do what I was just doing last summer? And so I go into these, these clinicals right in kind of the peak of COVID. And the veil gets lifted a little bit on some of the negative things that were going on in the medical community. I was forced to get the COVID vaccine. I was told that, you know, I would get kicked out of medical school. And at the time, I was actually kind of drinking that Kool-Aid. I told my friends, I was like, you know, I think you might be selfish if you don't go get the vaccine. Because I was-and-a-dict of a lot of people did. I mean, that was-sue. As soon as I got the vaccine, I had a lymph node the size of a softball for six weeks of my armpit. I had chest pain
Starting point is 00:11:40 that sent me to the emergency room twice. Sent you to the emergency room. I had chronic brain fog. My exercise tolerant, like went to the floor. So many different things happened. And whenever I started to bring it up to my classmates or professors, it was kind of like this, don't talk about it. It couldn't have been the COVID shot. Maybe it was just COVID. It's a coincidence. Yeah. And then I get into the clinicals and, you know, we, I go into my emergency room rotation. We have patients that come in after car accidents. Anybody that comes into the hospital is tested for COVID and one of them happened to test positive. And that patient passed away on. unfortunately from the injuries of his car accident and is being labeled as a, you know, COVID-related
Starting point is 00:12:21 death. And so during that time, you actually saw this happen. Right. And so during that time, there was a lot of things that made me think, like, I don't want to be a part of this. I want to go to more of a preventative style of health. I don't want to deal with health insurance. Like, I don't want to be under that model. I think the health insurance model takes the art out of medicine in many ways. Makes it very algorithmic. For sure. If this, then that. Exactly. And it's, it's labeled as, oh, this makes it more efficient and more effective. When that's not really true, it takes the human out of medicine. That's what it really does.
Starting point is 00:12:53 So I decided I didn't want to go into surgery because, you know, surgery is one of those things that something's broken by the time they're coming to you. You're not preventing anything. You're just kind of trying to fix the problem and half those patients you'll probably see again because they're not fixing anything at a baseline level. Same thing with like, you know, internal medicine when you're in the hospital or all those other specialties, which I'm not hating on those. We're amazing.
Starting point is 00:13:14 were the best at treating acute conditions. Oh, no question. In the world. But it just wasn't for me. So I approached my mentor and I say, hey, look, I don't want to do surgery. He told me that he would look into PM&R, which for your viewers and probably you, I don't know if you know. PMNR stands for physical medicine and rehabilitation or physiatry or PMNR. There's like 10 different names and that's probably why nobody knows what the hell it is.
Starting point is 00:13:38 Yeah, yeah. But basically what that is is a specialty that asks the question, what are you capable of instead of what's wrong with you. Oh. And so I started looking into it. And kind of the history behind PM&R is it started back in World War II, back in the FDR days whenever he got polio or what we thought was polio, probably was, you know, Gianbre or something.
Starting point is 00:14:01 Yeah. But the whole country was looking towards physicians to create more of a system that allows us to deal with soldiers coming back from World War II, dealing with insane injuries that we didn't see beforehand. Right. So we needed to create this kind of. rehabilitative space that medicine could be a part of. And from then, that's transpired into, you know, inpatient care for traumatic brain injury, spinal cord injury, stroke, amputations.
Starting point is 00:14:26 And then the outpatient side is more like non-operative sports medicine, interventional pain. So things like spinal injections. And all of that to say, I kind of look back now at my time as a kid at the Andrews Institute, like peeking through the glass. And I realized that half those doctors that I thought were orthopedic surgeons were PM&R doctors. Ah. And so I knew that I wanted to go into a more functional style practice. And I figured that if I could just take everything
Starting point is 00:14:53 that I knew or was going to learn currently, I'm in residency in PM&R, and apply that to before disability or function is lost. Yes. You know. I think that's such a great. You have a saying that's, so I have a saying that aging is the aggressive pursuit of comfort.
Starting point is 00:15:10 And you talk about how the most, dangerous drug right now is comfort. And the number one side effect of comfort is chronic disease. Yeah. For sure. I mean, we live in a society where everything is becoming more comfortable to us, and yet we're getting sicker as a society, and I don't think that's coincidence. Yeah. You know? If you want protein to build lean muscle, but without the caloric impact or need to cut, you need perfect amino. It's pure essential amino acids, the building blocks of proteins, in a precise form and ratio that allows for near 100% utilization in building lean muscle and no caloric impact. So we build protein six times as much as way, but without the
Starting point is 00:15:49 excess body fat we normally get during bulking. This is the new era of protein supplementation, and it's real. If you want to build lean muscle without having to cut, you need perfect amino. Now let's get back to the Ultimate Human podcast. So you think that these, you know, if someone's listening to this podcast, then I'm going down the road of, I'm going to touch on female hormone therapy, I certainly want to take a little dive into peptides and GOP-1s because you sort of view them as a double-edged sword, which I would agree with. But if we were taking a step back and someone was like, you know, look, I am in the pursuit of living the healthiest, happiest, happiest, longest life that I could live, where does somebody start? What are the, what are the biomarkers that they should
Starting point is 00:16:40 be aware of and familiar with, what kind of testing should they do to develop this baseline? And what is sort of a blanket recommendation that you would give to every patient that walks to your door, hey, you know, get your arms around these three, four, five things. We'll take a deep dive into your labs and then we're gonna go from there.
Starting point is 00:16:59 Yeah, so I think we're visual beings. Like I think we want to see results, not only in our body, in the mirror, but we also wanna gamify things. So in my mind, you know, me going and getting comprehensive labs, it's almost a competition of myself of like, let's see if I can do things from here the next six months so that the next time that I test, I know that I'm in a little bit better space than I was the last time. And that was nothing, that was something that I didn't go through
Starting point is 00:17:23 when I was a patient. Actually, I didn't even get labs drawn one time whenever I would get tested for strep. And there were no follow-up visits. There was no trying to get to the root cause. And what I saw in the clinical space in, you know, family medicine and internal medicine practices outpatient was that we were, doctors can only see patients for like six to 12 minutes nowadays. Yeah. And so not only do you take the physical exam part out of it because you can't have the time to do that and take a history and do all of those things that we used to do very well, but we also don't get enough labs.
Starting point is 00:17:55 Like insurance isn't covering for a lot of these labs like APOB for your cholesterol because we know that that's considerably better than a lot of these like LDL markers. Sure. Fasting insulin. Like that's probably my number one favorite lab on the planet. Yeah. Because that goes out of whack, you know, possibly five years before your A1C goes out of whack. And so we can figure out if you're headed towards metabolic disease considerably earlier if your fasting insulin is elevated.
Starting point is 00:18:18 And what would be elevated? So I would say anything above 10 would probably, I would consider elevated. You want to get as close to five if not below five. In a fasted state. In a fasted state, you know, I would try to aim anywhere between two and four, ideally. But around five is not bad either. But yeah, I mean, I see people that have normal A1Cs and a fasting insulin of 19.
Starting point is 00:18:40 And it's like... You know the train wreck's coming. Exactly. But that same person would be sent home by their primary care doctor and they say everything looks good. You know, and when you have these elevated insulin levels too, you tend to see triglyceride levels follow
Starting point is 00:18:53 because, you know, that insulin is barring that, a little bit of that fatty, it's blunting that capacity to use, you know, fat as an energy source. Right. And so it builds up, and one of the first places it builds up in the blood. And I would argue that there is a much higher correlation between elevated triglycerides and elevated cholesterol than elevated cholesterol on its own, right?
Starting point is 00:19:17 I mean, these hyper triglyceridemia, which I don't know that there's a really good pharmacological solution to, but there's really good lifestyle solutions to, you know, precedes a lot of these cardiovascular risk markers. And yet when we go just after that LDO, cholesterol. You see on most of these panels, it's HDL, LDL, VLDL, triglyceride. That's kind of it. Right. And everybody's looking at their total cholesterol and saying that number when that number really is meaningless in the grand scheme of things. Right. And why is it meaningless? Well, it's because it's a breakdown of all of those other things, right? Like you could have so many different ratios of your HDL to VLDL to LDL. And so saying total cholesterol is
Starting point is 00:19:58 meaningless in the point that you have to take a deeper dive like we're talking about. And of itself is not diagnostic for cardiovascular disease. Yeah, it's just saying like, oh, there might be a problem, but not actually telling you anything about the story. Yeah. So you want people to look at their insulin, they're fasting insulin, so they're probably also the glucose and hemoglobin A1C to see where they're staying. What other markers do you think that people should become familiar with
Starting point is 00:20:22 and get their arms around to get on this gamify schedule? Because I love that idea of, you know, I think a lot of people are like, well, if I don't know, it's probably better. You know, because everybody thinks, well, what if I get this test and I find something really, really bad? Yeah. Well, if you do, then you can fix it. You're probably catching it early.
Starting point is 00:20:40 And we know in nearly every form of disease and pathology, early detection is your best way, you know, out. Right. But so insulin, like your glycemic profile, what other markers do you think are important, especially in the younger generation, to look at, you know, as developing this baseline so they can make modifications.
Starting point is 00:21:02 Well, I think the hormonal stuff too. I think it's good to have a baseline of testosterone, not saying that you should get on testosterone replacement therapy when you're 17 or 18, but at least knowing what your baseline is whenever you're peak puberty, right after puberty, kind of in your prime years, so that when you get to that 30, 40, 50-year-old mark
Starting point is 00:21:19 and you're having symptoms like brain fog, fatigue, little libido, you can see what your levels are then, compare them back to whenever you were 18, 20, 25, 30, and see if that might be the problem. Right? Because if you're at a testosterone of 450 or 500 since 18 and you never had problems and then you test at 40 and it's 450 or 500, one doctor that only sees one value might say, oh, it's probably your testosterone will give you that.
Starting point is 00:21:44 But I'm like, no, I didn't have problems back then and it was the same marker. So I'm a big fan of trending everything because that's the big thing. It's like, sure, it's great if you go get comprehensive labs done once. I can tell a lot from that. But what's so much better is tracking those over years because then we can see a lot. acute change. And we talk about other lab values. Homo cystine is a great one just to track overall inflammation load in your body, highly correlated to methylated B vitamins too. And that just intake and how well your body is to methylate. I know you've talked about HFR. High sensitivity
Starting point is 00:22:18 CRP kind of tracks the same sort of metric, but a little bit more geared toward cardiovascular health. There's so many different things that we just don't include in the regular panel that whenever I have a friend that says, oh, I just went and got routine blood work and they send me their blood work. I'm like, you know, if there's five or six different things that could really make a better picture here. I want to get these numbers right, which is why I'm looking at this paper,
Starting point is 00:22:40 but along with a colleague of yours, you helped develop, now published actually, inpatient metabolic rehabilitation protocol. So yeah, I think this is fascinating. So I will give full credit to Dr. Joe Stanley. He's over at the James Haley VA. He's the one that's put this together. I'm really just a supporting role backup dancer for him.
Starting point is 00:23:02 Backup dancer. But yeah, no, he's very passionate about it. And part of the reason why I chose the program that I went to is because I was doing my residency interviews. And I told all these program directors like, hey, I want to go into functional medicine, more lifestyle approach, kind of a root cause approach, maybe not even in the health insurance space. And I had five or ten program directors look at me like, you're crazy. You don't want to go in academic medicine. We don't want you at this program. and that's fine.
Starting point is 00:23:30 These guys that I work with currently were like that from the get-go. And it's hard to find people like that, especially at the VA hospital. I just don't see a lot of nuance there, not saying that's not. But he really went the extra mile and checked off so many boxes because there's so much paperwork to get anything done in the government sector. Oh, yeah. And has created this amazing program where we'll take one patient at a time who was originally in our inpatient rehab setting.
Starting point is 00:23:56 Let's say they got a knee replacement. they came to us. If they were an appropriate candidate and seemed motivated, we would talk to them like, hey, you know, we do this intensive program where you can come for like two weeks and we'll teach you how to cook. We'll teach you what supplements that you can get. We'll do a full in-depth lab analysis on you. We'll teach you how to go to sleep hygiene.
Starting point is 00:24:14 I mean, we really start from a bottom-up approach. And then we track their lab values over time and they come back to us. And not only do they lose weight, their, you know, depression scores go down. They don't need enough as many medications. medications as once we're on. Their total body inflammation goes down. Their arthritis goes away. I mean, all of these things in real time,
Starting point is 00:24:37 now that I've been there long enough and get to track these patients have gone down. And so now it's starting to raise the question in the government sector of like, oh, well, if we could do this in an efficient way from the get-go, you know, from the very beginning, then we avoid all these patients coming into the hospital later on. So shout out to Dr. Stanley because he's been amazing at that.
Starting point is 00:24:56 You know, Bobby Kennedy talks about that too. He's like, it's one thing to fix the broken system. It's another thing to just keep people out of the system. I just want to read some of these markers because for those, you know, my audience that understands what these mean. This is a seven-day intensive program that produced pretty remarkable results.
Starting point is 00:25:14 So in 36 days, one patient example, saw a triglycerized drop from 140, which isn't still extraordinarily high, but it's elevated. 140 to 55, so that's two-thirds. LDL cholesterol cut in half from 130 to 66. Fasting glucose from 145 to 121 and maybe the most remarkably homocysteine cut
Starting point is 00:25:36 almost exactly 50% from 9.6 to 4.3. All without a single new prescription. So no additional chemicals, synthetics, or pharmacological intervention. Food, movement, stress management, and intention. I love that you use that word intention. Right. One of the fascinating things about the research that we did in the mortality space was we knew
Starting point is 00:26:00 that if you wanted to cut human beings' life expectancy in half, all you had to do was put them in isolation. And when we talk about the basics to people about how impactful things like movement, stress management, intention, community, connection, and how food is medicine, they almost want to refute that, because it seems like it's too easy. And I would say probably the biggest thing that we did in that program is, and we've had multiple other patients since then, that was kind of the first one that we were like,
Starting point is 00:26:34 oh, this works. Yeah, yeah. But the biggest thing we probably did, other than sleep hygiene, which I think is amazing and we're all missing. Yeah, I want to talk about that too. Yeah, is we did a full elimination diet for 30 days and we put people back to a baseline level of inflammation.
Starting point is 00:26:49 What does that look like? What is an elimination diet? So it's basically cutting out things like your gluten diet, your soy, highly processed foods, pretty much everything that has a high tendency to be reactive in a lot of people. And it's not like you're just eating, you know, one thing over and over again.
Starting point is 00:27:04 You can still have a pretty decent diet doing that. But we cut it down for 30 days completely. Like, no questions asked, we have to cut all these things out. So what was limited? Soi dairy? I believe it was soy, dairy, gluten, gluten, any processed foods. Good.
Starting point is 00:27:22 We kept red meat as long as it was, was grass fed, grass finished. So we made sure that everything was sourced correctly to, or at least tried to be. You know, sometimes people's wallets don't, you know, they can't pay for certain up tiers or whatever. Right. Which is fine. So we kind of worked with everybody on what we could afford, what we can't, how we're going to do it. And any artificial dies, you know, we kind of went into the weeds a little bit on that.
Starting point is 00:27:46 Yeah. And then after those 30 days, it was arena no alcohol. That's a big one. Yeah. It's a massive one. And then after 30 days, we would reintroduce one thing at a time for a few days at higher doses. So like we didn't reintroduce, you know, starches. And then we'd reintroduce like gluten back into the diet. And if that person starts to, you know, and they're taking surveys this whole time of like their mentation, you know, their mentation, how they feel, their pain.
Starting point is 00:28:11 And if those levels start to drop, then we're like, okay, that's a problem. Let's cut that one back out. We'll reintroduce one more thing. And so it makes people more aware of like what they put in their body is how they're going to feel. Yeah. And then in addition to that, where they're, because you talk about stress management, and then I want to talk about sleep hygiene,
Starting point is 00:28:28 but what did you do for stress management? Were this meditation, was it breathwork, was it exercise, was a combination? Yeah. Our therapists work with the veterans and try to figure out what they want to do. Because if you don't want to do it, then there's no point in doing it, right?
Starting point is 00:28:46 Yeah. A lot of them in the VA system did Tai Chi, which is amazing because not only are you moving, but you're also getting a mindfulness aspect out of it. So you're kind of killing two birds with one stone, right? It's a little bit of a biohack in its own because you're getting a little bit of a workout and movement out of it and you're providing mindfulness, lowering stress levels.
Starting point is 00:29:05 And so I think that was probably the most impactful for them. Some of them did meditation. Some did yoga. It just depends on what their baseline functionality was like too. Some people couldn't tolerate yoga or Tai Chi. So we started with meditation. And then did you make mobility, like non-negotiable in this?
Starting point is 00:29:21 Absolutely. Some form of exercise. Any form of exercise. Even if it was walking, I mean, we have patients that can't walk to the end of their driveway, right? So like let's make it to the first crack of the driveway on Wednesday. And then let's see Friday if we can make it two steps past that. I mean, it's about meeting patients where they are.
Starting point is 00:29:34 Yeah. So, and we don't compare to anybody else that came before them or after them. And then after this whole thing, this is like one of the best things that I think. After they go through this whole protocol, we introduced them to those patients who had gone through the protocol before. and volunteer to become part of a support group so that when they get through it to the other side. Dude, I love this.
Starting point is 00:29:54 They have like a wellness support group. Yeah. This is awesome. It's amazing. Yeah, because then you feel like you're part of a community. You feel you feel connected, which is one of the areas of medicine we rarely talk about. You know, when people feel isolated, I mean, do you look at the number of these horrific crimes
Starting point is 00:30:10 that are committed by, you know, very often by teenagers, but they feel completely isolated, you know. they don't have best friends in a friend circle and community and connection. They feel like a loner. And I think, you know, this exacerbates all forms of mental illness, you know, PTSD, when people feel like I'm the only one that has this, nobody understands me. I'm unique in my suffering profile.
Starting point is 00:30:40 They're number one, probably less likely to raise their hand to get help. And number two, they just get inside of their own head. And this becomes like a snowball rolling downhill. It's a perfect storm with so many different things. You take social isolation and then you take what's in our food nowadays. You take the amount of prescriptions that we're giving people with multiple drug interactions. You take the vitamin deficiencies that those prescriptions cause and those side effects. There's so many different things that you take the food that they're eating.
Starting point is 00:31:07 I know you've probably seen the prison studies where they reintroduce whole food diets back into prison systems. Violence goes down. Violence goes down tremendously. There's also, you know, with kids in ADHD, you know, putting them on a whole food's diet has the same effect, if not better effect, than putting them on medication. Yeah. So there's so many things that we're living with
Starting point is 00:31:25 in this unnatural world nowadays that if we just kind of get back to our roots a little bit, we can fix things one by one. Yeah, I totally agree. You know, you often have talked about GLP-1s, and I feel like GLP-1s are kind of this double-edged sword. I mean, certainly they can be life-saving for people that are morbidly obese or type 2 diabetics,
Starting point is 00:31:46 have a lot of food noise, in their, you know, just in their environment because I would put sugar addiction and food addiction right up there with nicotine, with alcohol, with some of the most difficult, you know, addictions that we suffer from. And I think because food is such a widely accepted resource, it's easy to have that addiction right in plain sight.
Starting point is 00:32:12 You know, it's not like you're pulling out a handle of vodka. You know, you're just going for a Twinkie, you know. And so, you know, food noise, food addiction, you know, morbid obesity, type 2 diabetes, I think these are areas where GLP-1s have a massive role. But now, I mean, if you're listening to this podcast and don't know one person that's on a GLP-1, I would be shocked. Yeah. You know, it's not six degrees of separation anymore.
Starting point is 00:32:41 It's one degree of separation. Definitely. And, but you feel like they're a double-edged sword, too. For sure. And for what reason? So kind of going back to what you said, I think nowadays we're being targeted with sugar in our face all the time. You go to the movie theater and before you can even watch the movie, you watch that like salivating video of a Coke being poured into a bottle and you're just sitting there like, man, I need to go get a Coke downstairs. And so it's constantly in our face.
Starting point is 00:33:09 And so it's worse than it was 50 years ago for like my parents or my grandparents. Yeah. So I do think there is a little bit of targeting that goes on there. And at GLP-1s, so what I'm seeing on the plus side, yes, it's taking people that maybe have passed their threshold of point of no return and giving them a tool to be able to get back to a healthier life. And that's what we need to be treating it as is a tool, not the miracle pill, not like, you know, the fountain of youth, but just a tool to be able to use in the grand scheme of things. And I think the problem that we're all facing is that in a lot of people, we're trading obesity for sarco. So we're not only, exactly. So we're not only have more fat than we need to in society, we also have less muscle.
Starting point is 00:33:56 Yeah. And that's the double-edged sword right there because if, let's just say you take a GLP1 and you lose a bunch of fat, but you also lose all your muscle and then you try to get off the GLP1, muscle is the biggest metabolic organ that we have. It's a huge glucose sink that's independent of insulin. So regardless of your insulin insensitivity or sensitivity, you know, if you eat a big, meal and you have a lot of muscle mass and you are using your muscle. It's a sponge. It doesn't even use insulin to do that process. So it takes it out of your blood. It gives you that buffer for maybe
Starting point is 00:34:26 a poor diet every other day or whatever. And people are completely missing that. So you'll get skinny, but in a weird way, they're actually getting fatter because their overall ratio of fat to muscle has actually gotten worse. Listen, there's what I share on this podcast and then there's what I share with my inner circle. If you've been following me for a while, you know how I hold nothing. back here, but my VIP community, that's where the real magic happens. Picture this, you're struggling with energy crashes, brain fog, or just feeling like you're not operating at your peak, and you don't know where to get real answers. But here's what really sets this apart. You're not just getting my insights. When I have
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Starting point is 00:35:30 This is what works in the real world. The community launches challenges throughout the year where you get direct access to me and my network of experts. It's like having a personal health advisory board for less than $100 a month. Your health is your wealth, and this investment pays dividends for life. join the VIP community at the Ultimate Human.com forward slash VIP and step into your ultimate potential. Now let's get back to the Ultimate Human podcast. And I like that you think that metabolic testing and BMI testing should be a part of everyone's protocol,
Starting point is 00:36:04 understand where they are with their muscle and their fat and their visceral fat. So do you think GLP1s have a place in functional medicine, and if done properly with strength training and let's say the addition of peptides? 100%. I used to be anti-GLP1. When I first came out, I was one of those people that was like,
Starting point is 00:36:23 no, I think this is the pain of all existence. I'm a big fan of Redertitutide. I think that is going to be huge whenever it becomes more available. But now we're seeing that it's cardioprotective, even though they control for weight loss. So even the people that lost less weight or more weight had the same cardiop protective effect from GLP ones,
Starting point is 00:36:41 possible cancer protective effect. So there's all this data that's coming out of the uses. Neurocognitive effects. Neuroclamatory effects. For sure. And so we're starting to see all of these things that it could play a good role in as being another tool in the tool belt. But you and I were talking earlier.
Starting point is 00:36:59 I think one of the first steps is putting that conversation back into the clinic setting rather than kind of the back alley black market setting. Because we're not, you know, once the FDA loosens up a little bit, on peptides. I'm hoping that people don't have to go and find these things on the internet. Yeah. Yeah. I think the risk is, you know, not and I hear physicians
Starting point is 00:37:21 very often attack peptides and they will say things like there's no safety data, there's no real gold standard data, gold standard science on it. That is patently false. In fact, I'll make available as a link, an academic white paper with almost
Starting point is 00:37:37 800-sided research studies behind it. And some of these, were gold standard studies that led to pharmaceutical approvals in other countries. I think we are going to see a certain number of peptides, probably 14 of these peptides, moved back onto the bulk list, and be compounded by compound pharmacies so that you get stability, sterility, potency, where appropriate guarantees, you get beyond use dates so that, you know, these peptides are not expiring.
Starting point is 00:38:09 You get mixing and dosing instructions. and you get a protocol that doesn't help you, you know, build tachylaxis, this desensitization response. I think the future for peptides is very bright. I do too. And I'm an enormous fan of peptides. I'd love to hear where you fall and what are some of your favorites, how would they be used and what your clinical experience is with them.
Starting point is 00:38:30 So this is the most exciting frontier of medicine, in my opinion. I love it. I'm a massive fan of peptides. And so, and one of the sad things, too, we talked earlier about how the health insurance model, kind of takes the art out of medicine a little bit. I have talked to physicians that work at some of the highest performance academic centers in the world and ask them about peptides and kind of get this answer
Starting point is 00:38:52 like, oh, yeah, like I've heard about them. I don't really know much about them. Yeah. And it's like, okay, it's 2026. If you're a physician that's taking care of really high level athletes or just high performing people and you don't, you're just not in the system. First of all, you're probably working, you know, eight to six every single day, seeing patients six minutes a day.
Starting point is 00:39:09 you don't have time to look up the studies or look up what peptides are. But also, it's just not in that setting. And so it's really sad that we've taken peptides out of the academic space because we don't have the people that really need to get the word out on them and get more data and get better data on these things to head up those conversations. And it's like we need to get that back into the real world clinical setting because it's so exciting. I'm not saying every peptide is great.
Starting point is 00:39:37 There are probably multiple peptides that I wouldn't recommend people. But at least if we give it to a patient and provider interaction again, instead of like going and buying it from some third party, you know, back alley online place, then you can have the conversations about, you know, safety versus side effects. You know, what's the risk benefit ratio? What is this going to give you? How to mix it. I mean, mixing is probably the biggest thing.
Starting point is 00:40:01 Mixing and dosing is the biggest. All of these nightmare stories that you hear, a lot of them come from people that just don't mix it correctly. and they're giving themselves an insane dose or no dose. Right. You know? So, yeah, I really hope that they loosen the grip a little bit so that we as physicians can start learning about them more because many of us don't know anything about it
Starting point is 00:40:21 and then also put it back in the clinical setting so that we can talk to patients about it in the safe way. Yeah, I completely agree with you. I'd like to go through some of the peptides because, you know, peptides, first of all, insulin is a peptide. And GLP 1 is a peptide. We make a lot of these peptides endogenously. It's not a voodoo sort of fringe area of science that, you know, a couple of gym bros got together
Starting point is 00:40:47 and you started making cocktails like a lot of these SARMs and things like that that you see online. These are valid amino acid analogs. They're hopefully made by licensed compound pharmacies. And they're done with, you know, in high. So 9,001 clean rooms, positive pressure rooms, with real parameters around them so that the dosage and then the strength and the potency can be guaranteed. And having been in the functional space now for about 10 years,
Starting point is 00:41:21 you know, we have really seen, I don't want to say miracles with peptides, but, you know, when people are recovering from post-surgical, you know, injuries when they're trying to improve their performance, when they're trying to improve their recovery, especially in athleticism. You know, most athletes are not over-trained. They're just under-recovered. So what if we dove into this category of peptides and take GLP-1s, for example, something like a red at true tide? What's the appropriate profile for someone that is interested in in getting on Reda Trutide. And when should they be considering something like that?
Starting point is 00:42:02 Yeah. I think it comes in the whole picture, right? Like if you get full metabolic lab testing done, you have that conversation with your practitioner, you have some sort of metabolic disease that you want to address, whether that be central obesity or, you know, non-alcoholic fatty liver disease. That's the one that they really did all the studies on.
Starting point is 00:42:20 For Reda-Trut. For Reda-Trutide. And it's an amazing medication for, decreasing the amount of fat in your liver, which we actually didn't really have any medications for prior to that. I think at the highest dose, it had like a 100% cure rate of, or sorry, a cure of 80 something percent of people that were in the study at the highest dose over a span of like 50 weeks or something, which is insane. Yeah. I mean, that's really stubborn fat that's wedged into a vital organ that we're able to get down. So in that sense, I think it's amazing. We can
Starting point is 00:42:54 target these certain things that we know cause a lot of harm down the road. But also like, you know, some people want to do it to because they're obese and they just want to lose weight and like they want an extra tool in the tool belt. And I think that's okay. As long as you're getting enough protein, your strength training and you're doing it under the guidance of a physician and you know your risks, then I think we should be able to have these conversations and not talk down on people for getting on a GLP1 and doing these things. Right, I couldn't agree with you more.
Starting point is 00:43:25 I mean, I think there'll be a lot more common as functional practitioners realize that these are more than just a weight loss tool. And when they use the full spectrum of the implication of these peptides, let's talk a little bit about vanity because most people want to look better, they want to feel better, they want to have more muscles, they want to have less fat, they want to have clear skin. And so in the world of peptides, and there's the category of growth hormone peptides,
Starting point is 00:43:58 GHRPs, GHRHs, where do you fall in the growth hormone peptides? I've certainly taken them with phenomenal results. I think I'm in pretty good shape for 55 year old. I've been hanging with these 25 year old every morning with my son. Yeah. I don't think that, and by no means am I here to tell you how to get jacked. I'm not jacked and I'm not a weightlifter and I'm not a body. but I do feel amazing.
Starting point is 00:44:24 Yeah. And I don't have any knee hip, shoulder, rotator cuff, low back pain, and I exercise pretty intensely. I really attribute that to peptides because I can tell if I'm not regularly on BPC 157 and TB 500, if I am not cycling growth hormone peptides, I noticed degradation in my sleep.
Starting point is 00:44:47 I notice a degradation in my recovery almost instantly within four or five days, it can be like, I'm off my peptide dose. And I'm pretty militant about monitoring labs. I haven't seen inflammatory markers rise. I haven't seen markers rise in any of my liver enzymes or alkaline phosphatase. I haven't seen reductions in EGFR.
Starting point is 00:45:10 You know, my kidney function increases in bun or creatin. So I'm absolutely convinced that these can be a tool in people's toolbox to reach, you know, their goals. I did 75 hard over the holidays, which was difficult when you're going home. Did you actually do it? I did. You read the books the whole day? Yeah, yeah.
Starting point is 00:45:27 Did it all. The outside workouts are tough too. It's hard. Granted, when you're in Florida, it makes it a little bit easier. Yeah, Florida is. Michigan's hard to do 75 hard. That's 75 super hard. Exactly.
Starting point is 00:45:36 Yeah. So it was 75 kind of hard for us, I guess. Okay. But I used peptides in order to kind of help my process along. So I was taking BPC-157, $2,500. I did that for three or four weeks in the first stretch. just because I had never worked out at that volume before and tracked my whoop data.
Starting point is 00:45:54 And it was crazy because I just figured it would have more of a local response on any aches and pains. But my whoop data was amazing. I was getting green recoveries even though I was working out twice a day. Could be placebo. It was a hell of a drug.
Starting point is 00:46:05 But I was doing that. I was taking Cermorellin for a little bit of a growth hormone boost during that under the guidance. At night before bed. Yep. An injection at night before bed, five days a week, two days off.
Starting point is 00:46:16 Under the guidance of a clinician. So I took my lab, I took my labs before and after two, and all my lab results actually got better, not worse. So I was doing this under, you know, good care and guidance. So you're taking the BPC and the TB 500 for tissue and wound repair. Exactly. Can you talk a little bit about to the extent that you know that the mechanism of action of these and, you know, why would somebody take BPC 157 or TB 500? Yeah, so I know that they're a really great anti-inflammatory.
Starting point is 00:46:43 We don't really have a lot of data around. whether you should inject it locally versus, you know, subcutaneous. But just the anecdotal data that I've heard from numerous people with aches and pains in certain areas that do inject it more locally, they tend to get better a lot faster than they would before. So I was doing it, you know, I had like some golfer's elbow that I was working out with and just kind of pushing through. And so I was injecting it locally into that area. Got better within a couple of weeks. Then after that got better, I was just injecting it, you know, subcutaneation. And I just felt like I wasn't getting those next day aches and pains like I was previously.
Starting point is 00:47:24 And I'm 28 years old. So it's like what level was I really had before? I think that, you know, an older population might have a little bit better bang for your buck in some peptides because your body decreases the amount of those hormones that it makes over time. So I kind of went low and slow. And it really helped me. I mean, it really did. I did not expect to have as positive of an experience with that. high volume of training that I did.
Starting point is 00:47:50 You know, you've also talked about, I wanna go back to the muscle for a second. Gabriel Lyne says muscle is our metabolic currency. You've talked about muscle as medicine. I've heard Mark Hyman say, if you wanna live a long life, lift heavy weight. Yeah.
Starting point is 00:48:06 So, you know, there are a lot of iconic figures in this space that are really trying to draw people's attention back to strength training, muscle. You know, I notice in my parents that are, they're older, they're both, my mom's 80, my dad's 82, they're both very deconditioned. And, you know, my father, because he's partially handicapped, my mom, bilateral knee replacements. And cognition follows this decline in muscle function. So can you talk a little bit about the importance of strength training muscle beyond just what we see in the mirror
Starting point is 00:48:50 and why you think muscle is medicine? Well, one, I think we've just been paying attention to cardio for like the last 40 or 50 years, and we've realized that we're leaving an entirely important sector of human health, especially physical health on the table, which is strength training. And I think strength training got a bad rap from like all the gym bros back in the day
Starting point is 00:49:11 wanting to just get bigger. Yeah. And we've just kind of disregarded that. If we look at the mortality data, I think, you know, being strong compared to being weak has somewhere in between a, you know, 200 and 400 percent difference in overall mortality risk, right? Absolutely true. Which is massive. I mean, if you look at things like diabetes or hypertension or smoking, it doesn't even compare to that.
Starting point is 00:49:32 Yeah, and there's no pharmacological intervention that even remotely moves the needle like that. Right. So, like, yeah, like if let's just say, you know, you have diabetes, you can supplement insulin for diabetes for a pancreas that's not putting enough out or for, for, pancreas that's putting too much out and you're not sensitive you can't supplement for being under muscled right so it's something that we don't really have a fix for on the medical side and so it's really in the hands of the patient to be able to do that and there's so many benefits i mean it increased brain derived neurotropic factor so you talk about the cognition it also is that glucose sink so maybe you become
Starting point is 00:50:06 a little bit less insulin resistant which does wonders for your mentality too you've you've talked about you know Alzheimer's being type three diabetes right so muscle is in this grand scheme of being able to get you to a better level of metabolic health that all of these diseases stem from. So to me, muscle is the root of where all disease stems off from. Yeah, and I think that another message that is starting to resonate in our industry is that it's never too late to start strength training. And there are people listening to the podcast that are in their 60s, 70s, maybe even in their 80s, like my parents. And, And the benefits that they, even if they have gone their entire lifetime relatively sedentary,
Starting point is 00:50:53 or it's been years since they've been on a practice field for any kind of sport, there is enormous benefits from even starting today with a strength training program, resistant training program. There was a, the Lift Moore study was, I believe I came out a few years ago, was looking at, I think it was primarily women age 65 and older that either had osteoporosis or osteopenia. and they compared two groups of women. One of them was lifting heavy, like five rep max heavy for multiple compound movements, where the other was doing more like 12 to 20 repetitions, which is kind of what we originally would put people on because 20 years ago,
Starting point is 00:51:32 we'd say anybody that age don't lift heavy because you'll break something, right? But what you see if they're doing it in this controlled setting with a trainer that's making sure they have good form, not only did we stagnate bone mineral loss, We increased bone mineral density, which we never thought was possible before. That is so incredible. Yeah.
Starting point is 00:51:50 So you have all these people that we've been telling like, oh yeah, we just want to like play it safe now and just try to minimize how much bone you lose. It's like, no, no, no. If you're 70 years old, you can still increase your bone mineral density if you get on a good regimen. And it doesn't mean you have to go and start power lifting in the gym. Yeah.
Starting point is 00:52:06 But go in the gym, maybe get a personal trainer one or two times just to teach you how to do something and just get moving because it has so many good benefits to it. If you know me, you know I'm a huge believer in the benefits of hydrogen water. H2Tab delivers cost-effective portable tablets that generate ultra-clean molecular hydrogen at 12 parts per million, one of the highest concentrations on the market, with over 1,300 published studies showing benefits of oxidative stress, energy, recovery, brain function, and so much more taking charge of your health has never been easier or more cost-effective.
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Starting point is 00:53:06 Yeah. I think it's hard to talk about metabolic health and longevity without bringing hormones into the picture. You know, one of the things I really applaud the FDA for doing was removing the black box warnings from female hormone therapy. You know, Marty McCarrie's talked about how 50 million women unnecessarily suffered because of these black box warnings that basically bastardized the women's health initiative study and made women and practitioners think twice about hormone therapy because it increased their risk of breast cancer. Right.
Starting point is 00:53:43 You know, years ago, there were these correlated links between stem cells and cancer when we basically started peeling back the layer of the onion wasn't coming from the stem cells coming from the procedure. And so shedding a light on some of these, you know, misnomer's. It's so astounding to me how long sometimes it takes
Starting point is 00:54:06 to turn the aircraft carrier in medicine, right? Like, how long do we sit with this food pyramid? and how horrible was the war on saturated fat, you know, front cover of Time magazine, which literally led to this decades-long war on saturated fat. Demonization of salt over sugar. I mean, there's countless things that have. And yet the entire time in this hockey sticks spike
Starting point is 00:54:33 in chronic chronic disease. So how important is it to have your hormones checked? Are you a fan of bioidentical hormone therapy? For 100%. Yeah. 100%. And do you have an experience in female hormone therapy? So I'll tell you this right now.
Starting point is 00:54:51 One of my number one regrets, and it's granted it's nothing that I could have done, but is not knowing how beneficial female hormones were 10 years ago because my own mother didn't get on them. And now she's 60, 61 years old. It's harder for her to tolerate after she's gone 10 plus years in menopause. and I just know all the benefits that those can cause if you're able to do it in a smooth transitional way. Now, granted, women can get on hormones later
Starting point is 00:55:18 and still have good benefit, but if you're able to do it in that perfect balanced kind of ballet of going into menopause and being able to transition through that process with a good hormone clinic or physician that's well-versed in doing those things, then it's amazing for women because women have been looked down on,
Starting point is 00:55:37 for so many years. I mean, I remember when I was in medical school and I was talking to, you know, menopausal-aged women and they'd be telling me that they're having brain fog, less libido, fatigue, night sweats, all these things. And then I go and talk to the practitioner that I was working with and they're like, oh, yeah, that's just what women go through.
Starting point is 00:55:57 Yeah, yeah, it's just age. And by the way, we got a patient that's coming up in two minutes, so hurry it up. And then it's like, so we've just kind of brushed women aside in that way. And like you said, like Marty's book really, touches on this amazingly. Like that study back in 2002 or three with a women's health initiative was a faulty study
Starting point is 00:56:14 kind of to begin with. Yeah. The findings came out before the study actually came out. Yeah. And then when the study came out, you realized the findings really weren't statistically significant. They're using synthetic versions of all the hormones. And now we talk about how the healthcare space, you know, does patients wrong in certain areas.
Starting point is 00:56:33 One thing that we don't talk about enough is it really did physicians. is wrong in this way because we don't, we learn about bleomycin and all these other cancer drugs in medical school when 95% of us won't go into oncology, but we learn zero about hormone replacement therapy and that's the basis of human life. Yeah, it's so, it's so astounding to me.
Starting point is 00:56:54 You know, I, my wife and I, Sage, you know, we've done podcasts on this, we've been very vulnerable about it and very transparent about it. She did this Dutch test while she was going through menopause. And I'm telling you what happened to her three weeks after getting on hormone therapy after Dr. Sarder really dialed in her dosages was mind-numbing.
Starting point is 00:57:19 I mean, libido, brain fog, her water retention, her sleep, I mean, her cortisol and melatonin were completely inverted. The, her short-term recall, like the lack of brain fog, just the crushing exhaustion, the mood swings, all gone. Anxiety. I mean, it's one of the greatest antidepressants
Starting point is 00:57:42 that we can give a woman. Yeah. Anybody. Someone that's really close to me came to me the other day and said that her husband had just got on testosterone replacement therapy in his late 50s, 60,
Starting point is 00:57:52 and said that her husband is more patient than he's ever been in his entire life. And you think testosterone-roid rage, right? Exactly, right? It's just simply not true. So much understood. So where do you see, you know, what does the future hold for Dr. Moss?
Starting point is 00:58:07 I mean, what is your vision of your practice, your impact? You know, how are you going to bridge this gap between allopathic medicine and functional medicine to impact the patients that you're going to see? Yeah, so I think I want to, so I'm pursuing formal education also in the functional medicine space through a couple of places like A4M and all these places that you go to
Starting point is 00:58:32 and do online fellowships with because we don't learn that in the academic setting or at least not through that framework, right? Yeah. So thankfully I've had that my residency program is not brutal enough to where I don't have time to explore other things that I'm interested in. So I'm able to do that along with my formal residency training and with PM&R I get to, you know, do a lot of hands-on things like ultrasound guided injections
Starting point is 00:58:54 with PRP or stem cells. Oh, super cool. And so what I want to do is take that PMNR knowledge of, you know, how do we get a patient back to being as functional as possible, take the functional medicine side of, you know, how do we avoid chronic disease and kind of morph those into a good practice that 10 years ago when I was the patient, I wish that I would have gone to, right? Where you're recognizing things early. You're getting a sense of like what a patient's going through on a day-to-day basis. You don't just have to sit with a patient for six minutes and then push them aside.
Starting point is 00:59:23 Yeah. You can actually sit down. So, you know, I have a year left of formal training. So I'm trying to build that runway out a little bit and see what's possible. I don't think I'll operate in the health insurance space as it currently stands, or at least I hope I don't have to. I want to say this too. You've talked about the payer system too,
Starting point is 00:59:42 like the difference between cash pay and insurance covered events. Like just this is sheer voluminous difference in costs. Like the same CBC labs that they bill an insurance company $400 for a patient can get for $35. So I got last year when I had health insurance, I don't have health insurance anymore. I do crowdfunding, but I got estrogen, testosterone, free testosterone, sex hormone. I got five basic hormonal labs from my primary care doctor. And I get the bill in the mail and I paid $98. And I was like, oh, God, I wonder what they build insurance.
Starting point is 01:00:18 I looked at it. And they build insurance $1,500 for those five labs. And so I was like, okay, well, first thought is, thank God I have insurance, right? Yeah, and I only paid $98. Exactly. So I go back to the same labs website and I go to all. order those lab tests like I would be doing it for a patient. And I put all five of those labs in and see what it costs. And it's $66 total cash pay. So I paid more with insurance than I did if I
Starting point is 01:00:45 just went and paid cash. And I'm seeing this in a lot of different places, right? Like you see insurance bill for an MRI at like $15,000 when you can go pay $400 for an MRI down the street some places. So I think the cash pay system gets demonized a little bit because people think that the physician who ever owns the practice is selfish by going cash pay. And sometimes it is more expensive. But I also think that if you're trying to be preventative, the money that you spend on the front end could also save you a lot of money and heartache
Starting point is 01:01:14 and family trouble and all of these other things on the back end. Yeah, no question at all. We saw the same thing when we were starting our functional medicine clinic. You know, we would have, we started with a traditional insurance model and it just became so difficult to manage. I mean, that's why, like, really successful medical practices have an entire division that just does billing because you could get a PhD in billing,
Starting point is 01:01:42 and it would drive our clinicians up a wall because they would spend so much more time trying to justify procedures and write medical necessity letters for relatively simple procedures. Prior authorizations and jump the roof. You know, I remember, you know, woman walking into a clinic
Starting point is 01:02:00 with a irregular note in her upper axillary region. And it was nodular. It wasn't there six months earlier on palpation, you know, all the signs that you wouldn't want to see, you know, close proximity to the lymph nodes. And so she just said, okay, I want to order a biopsy and some additional imaging and got rejected.
Starting point is 01:02:21 Right. And so she wrote a medical necessity letter and it got rejected again. And eventually what she realized when she spoke to the insurance company was because the statistical incidence of cancer in that age woman was so low and this was considered a non-covered procedure
Starting point is 01:02:40 and she's like, I get that, but here is all of my clinical analysis, everything about my training tells me this needs to be biopsied and it needs to be imaged. And here's why, and then they gave her another whole framework to write another letter. So in the third letter, they finally covered.
Starting point is 01:03:00 I know somebody who has, who had prostate cancer and had to get, or sorry, testicular cancer and had to get his testicles taken out. And insurance denied his, their, you know, authorization to get testosterone replacement therapy for that the first time. So they had to go through an entire appeal process. It's like, how do you expect that person to make testosterone if they have no testicles? Right. Yeah, yeah.
Starting point is 01:03:25 I mean, so I think, you know, a lot of that idiocry, we're going to hopefully see change over time. But while we're waiting to change the system, keeping people out of the system is the best route. You know, the final thing I want to touch on, because you mentioned it in your approach to metabolic syndrome, with sleep hygiene. And I love that term, but I think a lot of people don't know what that means.
Starting point is 01:03:51 You know, how do we draw attention to our sleep? What are some hygienic, I'm actually about to do a massive two-day-free sleep challenge. I do them every quarter. But I'm interested in your opinion on what does good sleep hygiene look like to you? So I think a lot of people treat sleep in a vacuum. They're just saying I'm not sleeping well and they don't look at anything that's surrounding that event except for them lying down and actually closing their eyes.
Starting point is 01:04:15 And I see this all the time and you'd be surprised. But I think if you really look at everything that leads up to sleep, not only in the first couple hours right before you get in bed, but the entire day, right? Are you getting up in the morning and getting natural sunlight? I mean, that's, Andrew Huberman brought, you know, this kind of to the forefront. And it's been huge in that whole community lately because that cortisol spike that you get early in the morning from having natural sunlight. You can't reproduce that indoors. I mean, maybe with some sort of like 10,000 loom and.
Starting point is 01:04:45 Exactly. Yeah. But you, for most purposes, you can't reproduce that. So if we're not getting that cortisol spike in the morning that's coming down throughout the afternoon, then we're staying at a base. baseline level of stress hormone throughout the entire day that doesn't taper off at the end. And then we have that wired and tired feeling when our head hits the pillow of like, wait, I've been tired all day. I could have just fallen asleep at my chair at work.
Starting point is 01:05:07 But when I finally get to bed, I can't go to sleep because my mind is racing. So I think starting in the morning with natural sunlight as quickly as you can possibly get it. Like get that sun in your eyes. Don't stare at the sun. But then, you know, later in the day, how later are you having your meals in the afternoon, right? Are you eating at 9 p.m. and trying to go to bed at 10? Yeah.
Starting point is 01:05:27 So I try to get, you know, two, hopefully three hours before I go to bed as my last meal because you need that time to digest. Traumatic improvements. Yep, doing that. Cutting down the temperature in the room to, you know, I sleep anywhere between 66 and 69 degrees. Some people even go lower than that. And I think that because it brings your core body temperature down. Taking a warm shower can help do the same exact thing. Sona before sleep is amazing for that. cutting out light in your bedroom is the biggest one that I see.
Starting point is 01:05:55 I mean, we have our, whenever you see our room from the street, it looks like a haunted house because there's only red lights in our bedroom upstairs. I love that. So like getting, you know, amber lights in the bedroom so that you're not having that blue light exposure that is ramping your melatonin back down. Using a sleep mask whenever you travel, you know, we're in a hotel right now. I love all of this. Yeah.
Starting point is 01:06:17 I mean, there's so many things, using a white noise machine, if you have like a, a ton of road noise and stuff like that nearby. There's so many different. Magnesium glycinate is like so easy to do right before bed. It's fairly cheap supplement. There's tons of things. And also, I think one of the most underrated things is trying to get on the same sleep schedule as whoever is in the bed with you, like your spouse or girlfriend or boyfriend or
Starting point is 01:06:41 or whatever it is. That is huge because if you're getting, you know, if you're waking up at 10 a.m., but they're waking up at 5 a.m. and they're waking you up, you're not getting eight hours of sleep. And, you know, usually I find in couples, and Sage and I are this way. One is a deep sleeper, one is a light sleeper. Right. So, like, she can get out of bed 10 times at night.
Starting point is 01:07:00 I don't know. I mean, she could have a dance party on her side of the bed, and I would not even know what that's going on. I'm jealous. We're the opposite. Yeah. But if I, when I wake up, if I have to use the bathroom at night, I am so intentional about how I get out of this bed.
Starting point is 01:07:14 I mean, it looks like I'm trying to commit a crime. Yeah. I slide, I move my legs over onto the floor, I sort of slowly, you know, stand up because I know that she's so sensitive to, you know, me getting up, getting out of bed, and if I get right, you know, and then I sort of fall back into bed, throw my eye mask on, and I'm like right back out.
Starting point is 01:07:33 Well, she's up for another 35 minutes. Yeah. Because I've broken out of that sleep. But I think sleep, hygiene, whole food diet, mobility being non-negotiable, which you talked about, strength training, so fundamentally basic but so incredibly impactful. And it makes you feel amazing.
Starting point is 01:07:51 Like if you get good sleep, you work out, you look good in the mirror, so you have that confidence booster. I mean, when you start to string all of these things together, it's not a chore. It makes you feel and look amazing. So people are happier than they've ever been when they start to implement these things.
Starting point is 01:08:06 Love that you're saying that. So Dr. Clay Moss, how does my audience find you? How do they find out more about you? Yeah, probably. Mostly on Instagram is where I do most everything, just at DR Claymoss, Dr. Claymoss. Okay.
Starting point is 01:08:19 Just DR Claymoss, no MD, that's DR Claymoss. Yep, don't even have a website yet. I'm sure we'll get there at some point. That's all right. We're cutting dry at this point, but yeah, they can find me on there. I'm pretty responsive and everything, so people have questions.
Starting point is 01:08:30 That's phenomenal. You know, I wind down all of my podcasts by asking all my guests the same question. And there's no right or wrong answer to this question. But what does it mean to you to be an ultimate human? doing probably doing 80% of the things right and leaving 20% to actually be a human being. I think we get really caught up in all of these things a lot of times. And then I don't want to die and realize that I've been, you know, in a protocol my entire life.
Starting point is 01:08:58 Yeah, paralysis of analysis. Right. So just not letting perfect be the enemy of good, but also taking the steps to really do what you need to do. Taking care of your own health is the most selfless thing that you can possibly do. I mean, if you look at patients in the hospital, that have not been taking care of themselves, like, sure, the end of their life is, like, really sad and debilitating, but also at the same time, their family is the one that's really taking the brute into the force. Yeah. If you have a patient that's, you know,
Starting point is 01:09:24 really obese with diabetes that's spending the last few weeks or months at home and needs to be changed, dressed, taken out of the bed. If you take care of yourself, it gives you so much more ability to take care of others around you. And so in that instance, I think it's really selfless thing to do is to go and get checked out, start doing all these things and try to get back on track if you're not already there. So amazing. Dr. Moss, thank you so much for coming on the Ultimate Human Podcasts. We're going to follow your journey. I hope you'll come back on the podcast again. I feel like there's a book in the making somewhere. Even when you get out of residency, you've got a little time on your hands. We're going to head over into the VIP group right now. I've got tons of
Starting point is 01:10:03 VIPs that are so excited and have a whole list of questions for you. If you're interested in becoming a VIP. Just go over to the ultimatehuman.com forward slash VIP and I will see you live in one of these sessions. But until next time, that's just science.

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