The Ultimate Human with Gary Brecka - 276. Dr. John Kim: On Mold Toxicity, Mycotoxins, Heavy Metals, & Cellular Detox

Episode Date: June 9, 2026

You might think that once you tear out the moldy drywall and move into a clean house, your body finally gets to heal, but in this episode, Dr. John Kim and I get into why so many people do everything ...right and still can't shake the brain fog, the fatigue, and the gut chaos. The answer lives somewhere most testing never looks: a stuck "cell danger response," where your cells stay locked in defense mode like a fire alarm that won't stop blaring long after the fire is out. I'll walk you through how Dr. Kim uses his ENCORE method to finally shut that alarm off, because you can't out-biohack a body that's still convinced it's under attack. CLICK HERE TO BECOME GARY’S VIP!: https://bit.ly/4ai0Xwg Connect with Dr. John Kim Website: https://bit.ly/4x4xGAg  YouTube: https://bit.ly/4aqYgd0  Instagram: https://bit.ly/4acnBr7  Facebook: https://bit.ly/49G7KRt  TikTok: https://bit.ly/4xqaPQ3  X: https://bit.ly/3PFmMjN  Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij  AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD  AIRES: "ULTIMATE20 " FOR 20% OFF: https://bit.ly/4a3Duze  BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa  BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV  COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp  CYMBIOTIKA: "ULTIMATE10" FOR 10% OFF: https://bit.ly/4tjyluP  GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk  GENETIC TEST (USA ONLY): ⁠https://bit.ly/3Yg1Uk9  GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC  H2TAB: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg  HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S  PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn  SNOOZE: LET’S GET TO SLEEP!: https://bit.ly/4pt1T6V  WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW  Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show  04:30 Dr. John Kim's Back Story: Heart Attack  10:42 What to Do When You Discover Mold in Your System?  19:13 Testing for Mold Toxicity  31:26 Cell Danger Response: Definition, Testing, and Resolution  35:59 The ENCORE Method  38:26 E - Environmental Factors Affecting Health  47:45 N - Nervous System Regulation  52:18 C - Cellular Integrity  56:07 Stress Response Increasing Deuterium Production  1:00:24 O - Optimizing Detox  1:05:47 RE - Rebalancing the Microbiome & Enhancing Resilience  1:10:12 What does it mean to you to be an Ultimate Human? Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions.  Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript
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Starting point is 00:00:00 Mold is not just about the immune dysfunction or having allergies, it actually causes mitochondrial dysfunction deep into the cellular level, down to the DNA. Cells are like human beings. They behave in communities. This is the way that cellular activity influences other cells and how metabolically healthy cells can become metabolically sick because they're an environment with other metabolically sick cells. So it's vital for the cell membrane to function well. Unfortunately, dealing with mycotoxins and mold in general, it actually damage the cell membrane integrity. Unfortunately, these are not the types of infections and chronic conditions that drive you to the ER. They're ones that people learn to deal with. This reason why, when I work with clients, I want to empower you to be the best doctor for your own.
Starting point is 00:00:39 And this is one thing that I'd like to teach is enhancing cellular resiliency. I think there's such a positive expertise out there on what to do once you find these infections. How do we actually eliminate mold from the body? One of the things that worked out really well for patients, and you don't need to spend a lot of money on it, and there is a company that supports this. Hey guys, welcome back to the Ultimate Human Podcast. I'm your host, human biologist Gary Brecker, where we go down the road of everything,
Starting point is 00:01:18 anti-aging, biohacking, longevity, and everything in between. And I should add mold, mycotoxin, parasite virus, heavy metal, and everything that's affecting your body. You know, today's podcast, this is a guest I've wanted to have on for a long time because I have been deep down the rabbit hole with many of you for the better part of a year now, talking about how these chronic low-grade infections are leading to systemic disease and pathology
Starting point is 00:01:47 right before our eyes, not showing up on your labs and causing all kinds of conditions that we are chalking up to a consequence of aging or repeated infection or we're chalking these up to a consequence of our environment or stress or a job or a career or kids and it's none of those things. Very often, it is preventable toxicity
Starting point is 00:02:07 and today we're going to talk about some of the big offenders and how we can get them out of our body. Welcome to the podcast, Dr. John Kim. Gary, thank you so much. It is such a pleasure to have you. You know, before the cameras started rolling today, I talked about a lecture that I gave in Salt Lake City going back about two years.
Starting point is 00:02:27 And the first, the morning lecture, which was about genetic methylation, I actually got a standing ovation from this crowd of physicians. and then that afternoon, I did a 45-minute talk on toxicity. And we talked about mold, mycotoxins, heavy metal toxicity, and some of the consequences. And I was quite ridiculed. And I don't want to say laughed off the stage, but I could tell they were just being tolerant until my talk ended. And I actually had some E-E-N-Ts come to me after the lecture and tell me that.
Starting point is 00:03:05 they didn't believe in mold or mycotoxins, that these were everybody, they commented, everybody's got mold, it's in and out of our bodies, they're basically tired of the mold cult. And I think over the last two years, through the detox challenges I've had,
Starting point is 00:03:25 the experts like yourself that I've had on the podcast, people are accepting that these are real toxic loads with very real consequences. and I've been a part of, I've been really blessed to be a part of the journey of several people who have had young children with repeated sore throats where they were just about to remove their adenoids
Starting point is 00:03:46 and they found a functional medicine doctor and said, put the brakes on, this child has heavy metal mold and mycotoxins. Let's do a detox and see where we stand. And now they're three, four, five years symptom-free. So if I could for my audience, I'd like to back up to your story because a lot of the more influential and impactful people, really passionate people that come on this podcast, are passionate and purpose driven because they solve the problem in their life, a big problem. And at 33 years old, you had a major heart attack. I did.
Starting point is 00:04:25 And I hope it's okay if I say that because I already said it. No, it's okay. It's okay. I call it the pain to glory story. Everybody has their pain to talk about that. I want to talk about that journey because it gives my listeners the why. You know, why are you here? Why are you so passionate?
Starting point is 00:04:42 And at that time, I'm sure there were not a lot of resources available for you. You had to become your own citizen scientist. Thankfully, you're a farm D. So you have an intricate knowledge of cellular biology, pharmacokinetics. So at least you had a vantage point to start from and maybe intelligently evaluate what was. out there in the world, but I'd love for you to share that story. Yeah, absolutely. So I was 33 years old.
Starting point is 00:05:07 I just got back from my friend's wedding down in L.A., and this was exactly June 1st. And then three days later, on June 4th, that's when I started having this heartburn. I always had a heartburn issue. And I always had some kind of gut problem to begin with. I completely ignored it. And that particular day,
Starting point is 00:05:24 if to someone was at resonating even higher, and the evening, that pain shut down right into my left arm. Completely ignored it, went to sleep, woke up the following day, like an idiot, and then having to go back to work, and then mid-afternoon, that's when I decide to go to the urgent care center instead of the ER. And then the urgent care center of the doctor is like,
Starting point is 00:05:45 you're having an artifact right now. We have to get to the ER right away. Got into the ambulance, got to the ER, and even the ER physician, even the attending cardiologist, didn't believe that this 30-year-old guy who actually got the cholesterol lab report from my doctor six months prior,
Starting point is 00:06:01 they were looking at this, There's no sign of possibly actually having a heart attack, but this guy's having chest pain. So they were trying to rule out as being a paracarditis. And then when they did an equicardiogram, they found out that my ventricle wasn't pumping well. So it's actually a sign of ischemia. They brought me to the cath lab,
Starting point is 00:06:19 85% blockage in my LAD. And you're a widowmaker. Oh, my gosh. Most people are not that lucky. Especially for young people, right? Especially when you're in the 50s and 60, you have a compensatory mechanism in terms of your new formed blood vessels, basically,
Starting point is 00:06:33 right, to take care of that blockage. But generally for younger patients, they actually die quickly. You know, I had a cardiologist, I watched a cardiologist give a lecture, and he said, what is the first sign of advanced cardiac disease in, I think it was 35 years old, younger? Yeah.
Starting point is 00:06:50 And people gave all these answers, and he said the first sign of advanced cardiac disease is sudden death. Yeah. That's the first symptom. Absolutely. So God's got a plan for you, my friend. That was something that, well, I didn't know that.
Starting point is 00:07:03 But then I end up having to be in the cardiac ICU unit, staring at a wall for three days, wondering how did this happen? And then especially question in terms of what led to this process, right? Having to have a early cardiac disease at age of 33. And then I had this overweight physician coming in and telling me to cut out old meat, cholesterol and everything else. It put me on a toberstatin 80 milligrams. And I was like, this is nonsense. There's something wrong here. So I got home and I just sat there for seven days,
Starting point is 00:07:34 just wondering what could I have done differently. So I went to my function medicine doctor, who I'm good friends with, she actually asked me, I think you're dealing with tick-borne illness. All I wanted to do was a vitamin C drip. Tick-porn illness. So she did a blood work and then after a month and a half later, that's when we've tested positive for espegillus antibodies,
Starting point is 00:07:54 IgM, IGG, Bartonella infection, Michael Plaza pneumonia, Epstein-Barr, mercury poisoning, on top of parasitic issues. So why does it occur? Well, there's an endothelial damage that occur from a Bartonella infection,
Starting point is 00:08:08 which is a cat scratch fever, which is common you could get to get from a tick-borne illness, including a spider bite. So I actually was in Boy Scouts all my life, and I probably ended up to contract it that way. Okay. And then I lived in a very moldy house
Starting point is 00:08:22 to begin with growing up. Right? And then also lived in a very stressful environment growing up as well. Living in an immigrant family, parents are constantly working, busy, et cetera. So that led to a lot of the newer inflammation that was dealing with. And as you know, all the cascade in terms of inflammatory response goes from the gut. So I always had a gut problem. And that was something that I should have caught, but I was just busy.
Starting point is 00:08:48 And the unfortunate thing is that a lot of Americans, including entrepreneurs and executives and people that you work with, I'm quite sure you have the same issue. where they're busy. We don't listen to our bodies, you know. It sends us signals. It does. Yeah. And I wasn't listening.
Starting point is 00:09:02 Yeah. You know, so that's when I already had an existing problem to begin with. I had anxiety left and right. I could not sleep that well when I was in my 20s and 30s. And then when I actually had that heart attack, that's when I stopped to listen and figuring out what's going on. And I got the answer. And it took me about two years to clear it out.
Starting point is 00:09:20 But it was a very tough process. And that was the moment that I found out how cellular intelligence. integrity is so vitally important for your health. And this is when started diving into lipid membrane medicine, right, and utilizing phospholipat therapy and all these... Coalene... IVPC. I've done that too. Yep.
Starting point is 00:09:42 But specifically at that time, I got connected with Dr. Ed Kane, who's a founder for Body Bio. And he actually read my red blood cell fatty acid analysis. And that particular test is very special, run by Kennedy Krieger, looking at the entire structure of the cell body bio. membrane, looking at the lipoproxosomes and the renegate fats, looking at the fluid index of the actual cell membrane, and he designed a customized lipid therapy that I had to go through. And my goodness, for four months, I was severely sick because all that toxins dealing with was just
Starting point is 00:10:14 getting dumped out, and my body, especially my nervous system, was not ready for it. And I learned a lot from that point on. And how I approached the clinical approach and dealing with mold toxicity and KAS and and all the different hyper-biotoxin issues that people dealing with, my approach is very different compared to what I had to go through back in 2015. So this is how everything came into play. So I was able to clear out Bartonella mold toxicity issues,
Starting point is 00:10:41 heavy metals and such. Can we go into some of the details of that because I think there's such a positive expertise out there on what to do once you find these infections? How do we actually eliminate mold from the body or in some of these micro toxins? how do we cleanse the body of heavy metals? I'd love to start with mold
Starting point is 00:11:00 because I really do feel like the medical community is finally starting to grasp. These are real infections. They have real consequences. Like we were talking about before the podcast started, unfortunately, these are not the types of infections and chronic conditions that drive you to the ER, like your heart attack or take you to the urgent care.
Starting point is 00:11:19 They're ones that people learn to deal with, right? They just tolerate them. you tolerated the gut issues probably for years before it manifested in something that drove you to the ER. And getting a hold of these at that stage when, you know, for people that are tuned into their body, you know, why do I have constant diarrhea, then constipation, then cramping, then irritability, then bloating, then gas. And it seems to be intermittent and not related to what I'm eating, you know, am I fatigued all the time? Why do I seem to have brain fog at such a young age? These are sort of signs your body's throwing up there you need to pay attention to.
Starting point is 00:11:58 What was the detox protocol? What did that look like for you? You said you did the PC. So at that point in time, my doctor put me on body bowel PC from the gut go because we had to deal with the intravascular inflammation that I was dealing with. So that was something that's really vital there.
Starting point is 00:12:14 But also when you're looking at the disease states of a heart attack or any type of cardiovascular or even types of infection, that's a sign of a mitochondrial dysfunction to begin with. So that's when the lip and membrane medicines is so vitally important to adding in the proper fat to quench the actual inflammation that was going on. So you're working on the upstream issue instead of the downstream problem that the person's dealing with. Right. So that was really, really vital there. And at that point in time, my doctor noticed that I was dealing with biofilm issues
Starting point is 00:12:43 as well. So adding a biofilm buster. And there are companies out there utilizing different things. I mean, you could end up using prolidic enzymes, like netopchinase or serapidase, nestsil-scyne, phospholipid, like body bowel PC I mentioned before. Great company, I had to take their PC. Right, so it actually act as a biofilm buster as well because it dissolves. It's an emulsifier.
Starting point is 00:13:04 It dissolves the biofilms, right? And one of the intricate part of biofilm is that when you have a history of taking antibiotic, for instance, right, and then overexture exposure to deal with mold heavy metals, and an immune dysfunction on top of this inflammation cascade, increased cholesterol cascade as well, all these are playing into the biofilm structure.
Starting point is 00:13:27 And when you have a biofilm, it's very difficult to utilizing antifungal antimicrobials to collect the infection. This reason why people, even though they might be gone through heavy amounts of antifungal protocol, they cannot get to the root of the issue.
Starting point is 00:13:42 So that's where oftentimes just using binders or antifungals alone, it's not going to fix the problem. You've got to really get to the root of the problem, which is biofom, mitochondrial dysfunction. But another thing that goes into play is the fact that these patients have trouble getting mycotoxins out to begin with because of their sympathetic nervous systems are overdridden. Things like detox, gut work, lymphatic drain, all these are deal with, your parasympathetic nervous system state. And oftentimes when you deal with mycotoxins, they already had an existing nervous and dysfunction to begin with.
Starting point is 00:14:15 But when you're dealing with micro toxins, especially chocothecens, which is a black bull coming from stockybotrys, it actually causes neural inflammation. It crosses blood-bent berry, especially gliotoxins, another one. And neural inflammation, I want to define some of these terms like biofilm and neural inflammation and not assume that my audience knows what those mean. Let's back up to biofilms. I mean, I have this image of like saran wrap kind of wrapped over your cells,
Starting point is 00:14:40 sort of preventing things from getting in and out and then the cell building up this level of toxicity. but also not being able to get the nutrients. But how would you describe biofilms? You know, what are they? The easiest way to explain is let us go to a lake and then you have a flat surface of a rock in the lake itself, and you see that there's a film, slimy film.
Starting point is 00:15:01 That's biofilm. Okay. It's part of our entire ecosystem for the microbials to protect itself from the environment. I see. But when you're dealing with mold, it colonizes in your system, in your body, and actually has to have that particular.
Starting point is 00:15:15 to deal defense to protect itself from the immune system, right? And one of the interesting part about mold is they cause it immunosuppression is one thing, but they also deal with the bowelphone issues. And then when you have mold, there's always heavy metal getting involved. So I don't tackle the heavy metal issues. I tackle that mold first, right? And then when you're utilizing proper lipid membrane medicine, especially using phospholipids, using essential oils,
Starting point is 00:15:43 and then butyrate has to be another plate to, effect because buterate is a chemical chaperone to help decrease that DNA adduct issue coming from these biotoxins to get the permanent removal of these things onto the monocon dna. Listen, there's what I share on this podcast and then there's what I share with my inner circle. If you've been following me for a while, you know how I hold nothing back here. But my VIP community, that's where the real magic happens. Picture this.
Starting point is 00:16:11 You're struggling with energy crashes, brain fog, or just feeling like you're not operating at your peak, and you don't know where to get real answers. But here's what really sets this apart. You're not just getting my insights. When I have incredible guests on the podcast, VIP members get to submit questions for a private podcast segment. So that world-renowned expert we just interviewed, you get exclusive access to their knowledge,
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Starting point is 00:16:51 The community launches challenges throughout the year where you get direct access to me and my network of experts. It's like having a personal health advisory board for less than $100 a month. Your health is your wealth, and this investment pays dividends for life. Join the VIP community at the Ultimatehuman.com forward slash VIP and step into your ultimate potential. Now let's get back to the Ultimate Human podcast. So when you remove these films
Starting point is 00:17:15 That is essentially a secretion from these toxins to protect itself from the environment When you remove these films now that bug is exposed Exposed right and once they're exposed Now you can kill them off and get rid of it with antimicrobials But you got to be careful too There has to be a step-by-step method there So I know you had another guest here talked about itchicotazole Yeah
Starting point is 00:17:38 Yeah, deal with that Yeah But one of the thing about those type of pharmaceutical drugs is that it's great. It works really well. And for people who are having over-conization in the old mold, it chocon is a great option. Unfortunately, it actually causes hepatotoxicity.
Starting point is 00:17:55 At the same time, it actually inhibits cytokone p-4503-8-4 enzyme, which is vital. In the cholesterol transplant chain. Oh, no, cytokone p-450, which is a phase one metabolism, right? So major drugs out there, statin drugs, for instance, Deltianism, which is a blood pressure medication, those drugs are metabolized by satacromp, P4-53-A-4 enzyme. So when you have a patient who is actually on those particular drugs,
Starting point is 00:18:24 which a lot of people do, right, and especially we talk about mold actually increases cholesterol production in the body. Yeah. These commonly actually are on stalin drugs. You cannot put itchreconazole on those patients right away. So you either have to take off the statins and then add in the, the echoconitis for a short period of time, but because of the hepatotoxicity issues, you got to do it for a short burst. You cannot be putting on a patient for six months straight.
Starting point is 00:18:48 So this is reason why, instead of actually going after those things, you got to fix the vital point. What is that? Your gut function. There's a condensation of mold in your gut. And we could talk about why later, but that's something that first you have to do. And then while you're doing that, you try to lower the actual mold burden in the body. and then once it gets lowered enough, that's when you start to work on the systemic issue dealing with mycotoxins there. So what would be, what are some of your go-to-to-test
Starting point is 00:19:16 for somebody that's having the types of symptoms that we've been talking about on the podcast? Rainfall, chronic gut issues, weight gain, water retention, poor focus and concentration, hormone imbalance, because a lot of these are estrogen mymetics. They're going to go and get a standard panel
Starting point is 00:19:37 they're going to get told they're fine. You could still stand a panel. There's a lot of story that could be told from the standard panel. Unfortunately, not even just that. The issue is that the conventional medicine right now does not know how to read functional blood work correctly. So there are blood panels in terms of the ranges
Starting point is 00:19:58 and then there are the functional ranges and there's optimal ways into looking at the blood work correctly. So you could tell about the story where the person's going through, but another thing is that you have to look at, is the biggest question is, what are you trying to find? Right? So we talked about your micro toxin, for instance.
Starting point is 00:20:14 So standard lab that I look to look at is real-time lab, urine micro toxin testing. Okay. So this is something that looking at the metabolite, the micro toxins that's coming out of the urine. There are certain limitations. There's no perfect test out there. But that's a gold standard I am to recommend.
Starting point is 00:20:31 Okay, I'm going to put a link to that. Yeah, so that's number one thing. And I also looking at organic acids. testing. Why? We want to look at the mitochondrial dysfunction. How's the crept cycle functioning? So looking at lactate, pyruvate, right? You're also looking at the glutathione production as well. We were based on the organic acid testing. You could also look at your transmitters. So these patients oftentimes very burnt down, low dopamine levels to begin with. So you got to work on their neurotransmitters. But it's not the point that's giving more supplements.
Starting point is 00:21:02 You've got to get them outside to get the sunlight. UVA right into the eye. And she helps to create that natural dopamine the body really needs. And oftentimes when you deal with mycotoxins, they have photophobia. They have very high levels of sun sensitivity issues. They get burned very quickly. So you gotta build up that sun callous, but it has to be the focal point
Starting point is 00:21:23 until it's getting the circadian within really balanced there. So that is one of the things that we could talk about later. But organic acid test is really vital and important. The next test we're looking at is a company has a stool testing. I like to use a vibrant wellness, a gut sumer 5.0. We're looking at the full spectrum in terms of their gut inflammation markers. You're looking at the connoisseation of the actual bacteria.
Starting point is 00:21:46 Looking at some of the pathogens, especially you're talking about like parasites, other things like citrobacter and other types of E. coli, other infection type of it. You want to rule out whether that person's dealing with small intestinal bacterial overgrowth. Because if they actually have CBO, most likely they have CFO as well. small intestinal fungal overgo within the system. So you have to look at the comprehensive and that sense of it. By also looking at how well the gut is able to produce short-chain fatty acid. And if somebody gets SIBO, they put on high doses of antibiotics and just buying themselves a problem down the road.
Starting point is 00:22:21 Huge. And you cannot use probiotics too much in this scenario. Oftentimes, if you're using the right supplements at the wrong time, you get hurt very bad. Right? And this is a part where use of the right probiotic, but also use of immunoglobulins is very important. So the company called Microbiome Labs, they produce immunoglobin G, so IGG.
Starting point is 00:22:47 It actually is a binder that actually binds to selectively for E. coli, strap, enteracus, laparotene saccharide, which is LPS, which is a biotoxin itself that E. coli produces. And then the other aspect is actually binds to some of the mold colonization of the body. So that's a more of a gentle way into getting the gut function back. And I'm really looking at to utilizing spore-based probiotic there as well because that's less reactive on the patient dealing with CBO. But the spore-based probiotic actually act as an antimicrobial to deal with a bacterial overgrowth the person's dealing with.
Starting point is 00:23:25 So you have to do it more of a step-by-step approach into the sequential ways in terms of getting these issues instead of actually just throwing the whole thing at the person. and try to see what sticks. So we've done the test for the secretions from biofilm. We've done a gut stool test. There's no perfect markers out there to looking at biofilms. There's none. I mean, there are muscle testers out there
Starting point is 00:23:48 who are very talented to check if the person's dealing about biophilms. But when you're dealing with over-conciliation of mold, there's always a play. And then there's other multiple infections. There's always play of biofilms. And if you actually look at their person's history, if they grew up having strep throat issues, including their ear infection,
Starting point is 00:24:11 they had years of taking multiple antibiotics for a long time, there's definitely biofilm issue as well. So you've got to understand that that is an integral part of the entire protocol, but there's no perfect tests out there to check for that. I wish there was. So that's the reason why a lot of doctors, including functional medicine practitioners,
Starting point is 00:24:30 they don't often miss that part. Right? That is vital, but they often miss it. So I was looking at it and says, all right, so what is, how's a person's history, how's a function person's happening, but also how reactive are they?
Starting point is 00:24:44 Right, if they actually are reactive in terms of food, chemicals, especially if they go in an Uber, for instance, and then they actually have a car fashion in there and they're getting reactive, they're having brain fog, they're wiped out for two days. That person has major industry dealing with MCAS, which is mass activation syndrome issues,
Starting point is 00:25:02 hypersensitivity, but also play the fact that there's a big play of biophones that's happening there. Right? You know, it's also important not to go too far too fast with these patients. You know, I've, early in my journey and functional medicine when we opened up our clinic, you know,
Starting point is 00:25:20 we, a lot of people were coming in for weight loss. This is pre-GLP ones. Yeah. One of the things I noticed about very obese patients that go through rapid weight loss is they become so toxic, migraines, rashes, you know, crushing fatigue, like fatigue where they can't even get out of bed.
Starting point is 00:25:41 I'm not talking about somebody who loses 15, 20 pounds. I'm like somebody's going to lose 100 pounds, 150 pounds. And the release of these toxins without fixing their detox pathways, which is something that I learned, was kind of fascinating to me because, you know, there are a lot of these toxins that are trapped in these fat cells.
Starting point is 00:26:02 And the same thing is true when you start going after some of these infections, especially sporulating infections, infections that are secreting these biofilms. That in and of itself becomes another toxic load. Huge. Right? It actually causes more activation of the immune response,
Starting point is 00:26:20 so that could be a big problem. So in case and point, talking about mold in self, like micro toxin, it's lipophilic. Right, actually lodging the fat cells. a lot more readily and the tissues itself. So that's why when you're doing a urine micro toxin testing, let's just say person's obese,
Starting point is 00:26:36 they've been chronic exposed to mold toxins in a moldy house. Oftentimes when you're doing urine microtoxin testing, their levels of mycotoxins are very low. Sometimes you don't even see it. So what's going on? The fat is basically holding onto that. So you need to really do a provoke urine testing to get the urine micro toxin out.
Starting point is 00:26:56 So you've heard of provoke urine testing for heavy metals. Yes. Same thing in this scenario. I didn't know you could provoke it for... Yeah. So what you do is you want to utilize minerals and bioflabinoids to stabilize
Starting point is 00:27:08 mycotoxins and getting that out of the kidneys. So use of molybidum, for instance. It's great to stabilize gliotoxins. Right? You actually have respiratory and turmeric, another good bioflavinoids in there. Right. So there's a company out there,
Starting point is 00:27:24 the company name is A-Lite. My mentor, Dr. Jill Krista. She formulated that thing. that entire supplement just for mycotoxin purposes, and I use it a lot. And one of the key supplement that I utilize now is called a color guard. Utilized all those things in there
Starting point is 00:27:39 are tough to solublease mycotoxin so that you get the patient for about two weeks prior to collecting urine so that you get a proper reading on it. So that's one way of doing it. There's some doctors who... And those are oral? Oral.
Starting point is 00:27:51 Okay. There's some doctors who utilize sodium butyrate, for instance, which is why. Sodium butyrate is a chemical chaperone. it actually removes the DNA adduct all these micro toxins that binds to the DNA, removes it. So that's another topic that we could talk about too. But this is a really integral part and why mold is not just about the immune dysfunction or having allergies. It actually causes mitochondrial dysfunction deep into the cellular level down to the DNA.
Starting point is 00:28:20 So when you affect the DNA, it actually affects the epigenetic expression of the actual tissue in itself. And reason why, especially for women, why is it that they're dealing with a lot of things like lupus? You're talking about Hashimoto's, right? So these are all into play in terms of why these type of DNA ad hoc changing the epigenetic expression of the cell and the tissue itself resulted in an actual disease state that we see it right now. Yeah. So there's always a root cause. Yeah. And, you know, I've seen so many of these.
Starting point is 00:28:50 So when someone has this suspicion, they do these tests. You know, you said that you did the IVPC, the phosphodidylcholine, or the PK protocol, similar to PK protocol. I've done that too. I had some clotication in my veins, so I stopped after a little while. Oh, my veins are completely clas. I have to go through 14 IV sessions using IVPC, and it's very, it's great. You know, you get your mitochondrial function back very quickly. It's just very caustic for your veins.
Starting point is 00:29:21 Yeah. And it takes a long time to come back. It's not, you know, life-threatening or anything. It's not. It is a little ennerving when you look down and they're all hard and you can kind of roll them. And you go, I feel like that's a clot. And if that leaves, you know, am I going to... It's not going to happen that way.
Starting point is 00:29:37 No, it doesn't happen that way. You get scared initially. Yeah. Yeah. But it's also, you know, IV piece is great. Now, the issue is that when you're looking at the entire phospholipic complex, you're not just talking about fossil coaling. You're talking about fosinocytol, serene, and ethanolamine as well. So four different lip lipic, I'm sorry, fossil bit complex that we're seeing.
Starting point is 00:30:00 So when you look at a cell membrane structure, for instance, about 70% of the cell membrane structure, the outer membrane, especially. So when you, the audience out there, people don't know what cell membrane is, is a bilateral structure of your entire cell. Right. And that bilateral structure dictates in terms of how nutrients go in, waste going out, and then as well as that cell membrane potential to allowing different hormone changes and functions and everything else that goes on. So it's vital for the cell membrane to function well. Unfortunately, dealing with mycotoxins and mold in general, including other biotoxins, just like Lyme, it actually damage the cell membrane integrity. So specifically mold, for instance, it actually causes lipoproxidase. And then also depletes the cardiolipidin in an inner part of the membrane
Starting point is 00:30:49 as well. And then when you're looking at the structure in itself, the early stage of cell danger response is the mitochondria's role to cause a lockdown of the particular cell by increasing phospholipid production inside the cell to lock the cell in. And this is the issue where the lack of cell to cell communication that goes on, but that's the early sign of cell danger response. And why people are stuck in this process and why it is so vital that you work on that cellular health by utilizing these types of special lipid to actually help reverse these things as well. Can you describe what cell danger response is?
Starting point is 00:31:29 Yeah, sure. Cell danger response. Sounds terrible. Yes. So cell danger response was a term coined by Dr. Robert Navio. He's an MD PhD out of UC Davis. And he's still working right now and really doing,
Starting point is 00:31:43 he has a different metabolic lab that he does a lot of things. And he's able to prove in terms of what his theory was at that point in time. and he explained why certain disease states, especially like autism inspection disorder that he was working a lot with, why these patients are stuck in their healing process. Everybody goes to a cell danger response, right?
Starting point is 00:32:03 You woke up, that's a cell danger response. Yeah. Right? You're waking up, your cortisol level, shoot riding high, and you've got to do all these different things. That's a cell danger response. Everybody goes to it.
Starting point is 00:32:12 But why is it that some people going through a certain case scenario, and I call it the Humpty Dumpty effect. The reason being is the Humpty Dumpty is sitting on a wall, it's fine. But if someone comes in or some wind or something comes in and poke them aside, he falls over, he shawl completely cracks. And that's how unstable people are right now living. And unfortunately, COVID happening, it blew up the lid into how unstable these people were to begin with. So that's why a lot of people dealing with long COVID sequela issues right now. So that's all side of
Starting point is 00:32:46 cell danger response. So why, what is that? It is cell. It is cell. Angel Response is a evolutionary protective mechanism that the cell actually had built into the process to protect itself. From what? From biological issues like mold, bacteria, fungi, talking about parasites, including viruses. And then all the things like physical trauma issues, right? Could be TBI, traumatic brain injury, for instance, or other things like UV radiation. There are other things in terms of psychological traumas in terms of, emotional or PTSD, for instance. And then there are chemical stressors like heavy metals or glyphosates, right,
Starting point is 00:33:27 all these different things. But these are causing that much of stress onto the cell in itself. So instead of the mitochondria making ATP, now it's actually shuts that ATP production down, shuts oxytophospholation goes to complete defense mode. So this is where mitochondria dictates in terms of how the body is going to shift. But if the stress response is overwhelming, I talked about the toxic bucket effect, right? Everything's later in.
Starting point is 00:33:55 If that response is overwhelming, the mitochondria cannot get back to homeostasis. And then it's complete in that on-threat mode. Yeah, that sympathetic state, that fighter-flight state. So when you think about like a fire alarm, for instance, it's keep unturned on. It doesn't know when the fire was gone, but still keep on turning on. So this reason why people who, you know, had removed themselves from a moldy environment, for instance, they're still sick. Because the overall cell danger response has not been resolved correctly, resultantanato dysfunction, and they're consistently sick in dealing with autoimmune disorders, brain fog, fatigue problem, et cetera. You could do all the NAD you want to do.
Starting point is 00:34:39 You could do all the analytics and all these different things. But if you have an unresolved issue cellularly in dealing with toxicity, you cannot out. biohack yourself out of that. You've got to resolve that cell danger response correctly. What are the top three reasons why I prefer a vertical cold plunge versus a laydown tub? Well, I've used both. When you're in a vertical position, your body naturally regulates your breathing better. So if you're holding on to the sides and you're in a vertical position, you can just focus on your breathwork and you can stay calm. A lot of people feel more calm when they're in a vertical position than when they're laying down in the water and think they might slip under the water.
Starting point is 00:35:14 So when you're vertical plunging, you're fully immersed faster. You can focus on recovery, inflammation reduction, and you're not struggling to just stay in a lie-down position. Your body floats in an awkward way sometimes. So it's just a more efficient, comfortable experience in my opinion. It takes up way less space too. It has a smaller footprint. So you can put these on your patio, your garage, your bathroom, your locker room.
Starting point is 00:35:34 You can really put it anywhere. I've got one on my balcony. I've got two in my bathroom. So this is why Cold Life is my favorite cold plunge on the market. So click the link below and you can order yours today. make sure you get the ultimate human version. Now let's get back to the Ultimate Human podcast. And how do you start resolving this cell danger response?
Starting point is 00:35:52 Because I would imagine that you're going to solicit some of this cell danger response just by going through the detox process. Correct. And so as we detoxify and we go after these biofilms and eventually go after the bugs themselves, there's going to be a period where people may get worse before they get better. Correct. Right.
Starting point is 00:36:10 And you try to manage that by not going to, fast by having this graduated approach. In fact, you call it, which I thought was absolutely genius, the encore method. The environment, the nervous system, cellular integrity, which virtually nobody talks about. You know, Dr. Pampa, and there's few other leaders in this area, optimized detoxed and rebalancing the microbiome.
Starting point is 00:36:35 I think what happens is most people skip the ENCO and go right to the R and start balancing the microbiome. because they think as soon as you have gut dysbiosis, this is a probiotic floor issue, and therefore just probiotics, maybe some digestive enzymes, but the truth is that you're not getting rid of the toxins and the biofilms
Starting point is 00:36:54 and what's truly at the root cause of this, even preventing heavy metal detox, which is gonna allow heavy metals to build up, and even interrupting the methylation cycle for the proper use of light metals, right? Which is the way that we, you know, methylate and incorporate light metals like magnesium and zinc and B12. So, you know, once you've disabled or impaired this process, you have to repair that
Starting point is 00:37:26 even before you restore the gut microbiome. And I love that you put that at the very end. You know, because first you clean the terrain. I've been using this analogy so much on my podcast because I think it just said in such a clear picture. When a fish gets sick, the first thing. we do is clean the tank, right? And because it's so obvious. When you're looking through murky water, it's full algae, you know, it's full of dirt, it's cloudy, you understand why the fish is sick.
Starting point is 00:37:52 But when you're looking at a human externally, you can't see the cloudy water inside. And so we don't think about cleaning the tank. And this approach is a very restorative approach. I would love to actually just walk through the encore method. Sure. Because I think it's a great foundational framework for, identifying, removing the toxins, rebuilding the body's damaged cell membranes and fustolid bilayers, and then fixing the gut microbiome. So can you walk us through this method? So the reason that I came up with this particular Encore method was after learning and diving into the whole cell danger response method, when you look at Dr. Robert Navio's work of cell danger response, it's very complex.
Starting point is 00:38:39 And it's very difficult for you to take that information and put into clinical use of it. And so I was just thinking, like, what can I do to utilize this correctly for people who are dealing with biotoxin issues? Like if it was me back in 2015, if I had a particular methodology, what would I do differently? The first thing was basically the environment factor there, right? Environment, if you are stuck in the same environment that made you sick, you're not going to get better. No chance. I always say that. Right.
Starting point is 00:39:07 You cannot out biohack on that part, right? The environment is the best thing that you could actually into fixing. And this is a part is often difficult. The reason being is you live in a house where it's very moldy. It could be costly. It could be costing you $5,000 to remeate up to $150,000 or more. So people who have limited budget, that becomes a very triggering issue. So you got to first off, what you need to do is need to calm.
Starting point is 00:39:32 You need to really settle down in terms of art. So what are the issues that we're dealing with right now? Where are the most problematic areas? you need to find the right testing company to come in and assess the overall damage of the actual issue at the house. So I recommend a company called We Inspect. We inspect.
Starting point is 00:39:49 Great company, too, that is nationally recognized. And they are one of the pinnacle in terms of looking at how proper mold testing should be done at the house. It's not just about air sampling. That's the worst thing you could do doing air sampling tests in the house. Because depending on whether air is being stagnant
Starting point is 00:40:06 or being flowing, that micro toxin testing is going to be affected. Also, that's the reason why I prefer going with more surface testing. The reason being is micro toxin especially rise on the dust particles like a carpet on a ride. So that's where micro toxin settle in. So this is where when you want to looking at the overall sediment of the microtoxin burden that goes in the house, you're looking at that. So Ermi Test is a good one to looking at. And there are other testing companies that you could do as well on your own, if you like to.
Starting point is 00:40:40 It doesn't give you the overall comprehensive issues because it doesn't necessarily check for, like, water damages behind the wall, for instance. So the company called the Dust test is a great one that I like to utilize dust test. Okay. Yeah, it's like $279. You could do one sampling of the area to figure out, so how much of a micro-toxin issues I'm dealing with? Right. But it's just going to give you some pictures. But this is where you have to work with a professional company to look at that.
Starting point is 00:41:05 The second thing I would also recommend, if you could hire the same people that does it, great. But building biologists. Why? Non-native EMF. Why is that? And I'm a strong believer in this part now, more and more. The reason being is why is it that people are getting sicker and sicker even though we have advancing medicine and such? I mean, you could talk about food, the glyphosates and all these different things.
Starting point is 00:41:29 But when you look at the bombarding issue, dealing with the cellular stress that we're dealing right now with non-native EMF, it's over than anything we could actually fathom now. Compared to what it was 100 years ago, it's much, much greater. So we were looking at reducing that non-naive EMF exposure, especially hardwire everything in the house.
Starting point is 00:41:50 Maybe you want to reduce the exposure dealing with Wi-Fi signal. Cell phone signals another problem too, right? So you've got to get, in terms of removing that, But that could actually oversensitize a person who's dealing with hypervisional state. Like, for instance, if you're dealing with MCAS, I think you have Dr. Demsie on recently, right? Amazing. Yeah.
Starting point is 00:42:10 So, I mean, she's an foremost authority in the topic of MCAS. But when I see clients with MCAS issues, it's not the fact that-MASL activation-activity syndrome. It's not the fact that the mass cell is triggered by mold, but it's just the over-response of cell-dangered response that had gone. wrong that the body is in that hyperviginal state and you got to talk about non-native EMF. That's the really important fact. What you mean by non-native? Non-native EMF. So especially talking about Wi-Fi, cell phone signaling, right?
Starting point is 00:42:41 There is going to be EMF naturally, right? There's always different cosmic rays that actually occurs up in the sun, everything else in the universe. But when you talk about these non-native EMF that is artificially driven and built because of today's technology that we actually have, is bombarding ourselves. And non-ev EMF issues, what it does is cellularly, it actually impacts, it ligates a cell membrane, number one.
Starting point is 00:43:07 Number two, it actually activates the voltage calcium ion channel. So if an infox calcium going into the cell and then bumping out magnesium. So you have all these people who actually have been taking magnesium supplements that can't get it up, they can't get it better.
Starting point is 00:43:20 Why? Maybe they're getting overexposure to non-emf and mold issues that you're not even aware of. Yeah. So any time to look at, at the environment factor in terms of the encore method, non-ABMS is one of the top things I tell people to do.
Starting point is 00:43:35 And then second thing is blue light toxicity issues as well. So obviously I'm having a blue light blocking glasses right now. I usually are wearing mine too. What happened to my glasses, guys? Are those yours? Now I need to wear them. Give me those bad actors. All right.
Starting point is 00:43:51 Thank God. So blue light issues. Blue light actually affects methylation. Not anymore? Yeah. But think about it. People who are dealing with already MTHFR issues to begin with,
Starting point is 00:44:06 and then they are already getting bombarded with different types of environmental factors, and then you're getting the issue dealing with blue light toxicity, it overwhelms the response. Why? Because blue light affects them a thine pathway. You can't methylate well.
Starting point is 00:44:20 So all this discussion about methylation, all different things, listen, you're the first one, that's been out there speaking a lot about ventilation. I appreciate that. Thank you. But in a scenario like a person dealing with hypersensitive issues, you got to look at the environment as well.
Starting point is 00:44:35 That's just about the whole environment. You know, I've been learning this, you know, the last two years especially, and I'm always trying to evolve. And there were those cases where, because we had about 200,000 patients that came through our functional clinic. And I would say the majority of them, healthy young adults that were dealing with some challenges there. You fix methylation and there was some shift in the positive direction,
Starting point is 00:45:04 sometimes dramatic shift. Other ones, there was no change at all. And sometimes they would start over-methalating. They'd even have negative consequences. Those are the ones that I really started to focus in on. And in the last 24 months, I'm starting to realize that it's more than just methylation, right? You can see the genetic breaks, which
Starting point is 00:45:26 makes them susceptible, but it doesn't guarantee their outcomes. It's like the epigenetic model. But now that I'm further down the rabbit hole on these environmental toxins, that was the missing link in our practice that we hadn't quite closed the gap. We got the ball like 80 yards down the field.
Starting point is 00:45:47 We just couldn't move it that last 20 yards in a lot of people, and they were very resistant. to treatment. And this has a lot to do with what you're talking about. This has a lot to do with. Yes, totally. And then there's another issue where over-metallation
Starting point is 00:46:02 just mentioned before. Yeah. So in my practice, what I do is instead of actually going after the methylation first, I'm looking at the metto-transferous chlorine pathway. So if you look at that pathway itself, it's part of the whole homocystic cycling. If you look at that,
Starting point is 00:46:16 what is body producing, fossil chlorine and creatine? Yes. So if you supplement those two, It puts less stress on a homocysteine pathway. Person is not overreactive. Leaving more methyl groups for homocysteine to methyony. And the other big one that we uncovered was the saw,
Starting point is 00:46:36 you know, this hyperhomasysidemic symptoms, not coming from hyperhomocystinemia, but coming from elevated esotinosal homocysteine. And that's a very difficult one to test for. At least it has been historically because of the stability of how you have to keep the sample and everything else. And that was another big key that we unlocked.
Starting point is 00:46:59 But what you're saying is supplement for the methyl groups that are being overutilized in the homocysteine pathway so that you can leave more of that methylation cycle for the recycling of homocysteine, which has its own set of consequences. Most of these hyperhomocystinemic patients, in fact, above a certain level, we saw hypertensive results because of the vasco constriction.
Starting point is 00:47:28 We saw all kinds of consequences. And it's actually rarely tested even on cardiac panels. You know, we're all looking to see reactive protein and K and, you know, the classic markers, but not looking at what could be irritating those pathways. So these are things that we are looking at there. And then looking at the environment, more factors in terms of the person's trauma, how the relationship they are living inside the house. Are they living in an abusive household?
Starting point is 00:47:58 How's their work environment? All those things are really important. Their generational trauma is a big one too. Yeah. Right. So this is the part of the E, the N of the Encore method, dealing with nervous system regulation. Oftentimes because of the microtoxin causing neuroinformation, these patients are in a hyper-driven, hypervigilant sympathetic nervous system state.
Starting point is 00:48:17 So how do we create that parasympathetic? One of the things that worked out really well for patients, and you don't need to spend a lot of money on it, and there is a company that supports this. I do heart math breathing, called a heart coherency breathing technique. Wow. So you probably heard a box breathing technique.
Starting point is 00:48:33 Oh, yeah, yeah. And heart coherence, too. Yeah. So heart coherency. Why this is such a different thing is that when you're doing that heart coherency breathing technique, it creates the coherency state from your heart to your brain, and that helps to calm
Starting point is 00:48:46 a lot of the issue dealing with mass cell, immune dysfunction, and then much more in terms of the hypersensitivity that person dealing with. So how do you do that? Yeah, I was going to say, can you describe this first? Very easy. All you do is close your eyes and then focus on the center of your heart. And then afterwards, you want to focus on what is making you happy, joyful, and grateful about.
Starting point is 00:49:10 So when you think about those three positive things, what it does is shift your overall brain state into a coherent. based on the positive affirmation and thoughts. And while you're doing that, you're going to breathe into the nose five seconds, and you're going to exhale out, five to seven seconds. Inhale to the nose again, exhaling out.
Starting point is 00:49:39 One more time, inhale, exhaling out. And that is it. Better. Yeah, that's all I do. So what I also recommend the patient to do is I give them, actually. It's called a heart mat device. It actually checks for your coherency state
Starting point is 00:49:58 between your heart and your brain. And there's a fine feedback about you. You just put your ear and the company called Heart Math actually sell this. Heart Math. Yeah, Heart Math. So that's an institute that trains physicians and clinicians out there to doing this particular breath work and management of nervousness dysregulation by creating coherency state and not only affecting positive ways into the body, but also working in terms of deep-rooted issue in terms of trauma issue as well. Why?
Starting point is 00:50:25 your heart actually is another nervous sensory as 40,000 different nerves stemming from the heart and then is able to take in all that information and bring it to your brain, not the brain to the heart itself. So you think about a person dealing with trauma issues, hyperviginal state, all these different things. Once you create the coherency state in the heart, or a lot of symptoms end up have to disappear.
Starting point is 00:50:48 I'll give a perfect example. I had a client who actually lost her son 18 years ago, had a boating accident, the sun fell off a boat, watched the sun died. She constantly dealing with hypervigilant state, anxiety, et cetera, was affecting her life. And she was not ready to do, to work with me. And I do work with clients one-on-one.
Starting point is 00:51:08 And all I did was taught her how to do this particular breathing technique. Her resting heart rate used to be 90. After six weeks, her resting heart was at 60. Wow. Yeah. Crazy. I couldn't even believe it. That particular change.
Starting point is 00:51:23 And one thing that you start noticing is that the person's face completely changed as well. Why? Because they're not living in the stress response state anymore. You're in a coherency state. Hey, guys, let me tell you about one of my favorite new hydration drinks. Now, this is for distance athletes, hits cardio exercises, people that sweat a lot or exercise intensely. An A game is a hydration drink. It has eight essential vitamins.
Starting point is 00:51:45 It has all of the electrolytes, the entire suite of B vitamins. Before you freak out and read that it has 21 grams of sugar, which it does, the sugar is coming from now. natural cane sugar and honey, my preferred mechanisms for getting glucose into the blood during intense exercise. It also has natural flavors, but these natural flavors don't come from bacterial fermentation. They actually come from real citrus fruits, and the color is from vegetable juice, not artificial dyes. So next time you're looking for a great hydration drink and you're exercising intensely, a game is your choice. Now let's get back to the Ultimate Human Podcast. So this is why when you're working with people dealing with botoxins is so
Starting point is 00:52:23 that not only you work on the environment, work on a nervous system. I love that. Because environment, nervous system now affects your cellular health, right? Your mitochondria is not just about making an immune system as well. So it's not just about making ATP. Mottocondria is a sensory organelle
Starting point is 00:52:40 is able to dictate everything that goes in the body, including the mitochondria dictating just how you methylate, also how you detox, but also how you heal. So fascinating, you know, connectivity. I've always said that some of the worst experiments that we do are when we take structures out of the body, cells out of the body, what have you, and we look at how they behave in a
Starting point is 00:53:00 laboratory. And then we assume that when we put them back in the body, they're going to behave the same way. And they don't. I mean, because cells are like human beings. They behave in communities, you know, and there's something in psychiatry called the herd mentality, right? you're in a crowd, if the crowd starts surging and everybody just starts running one direction, you'll just start running. You don't even know why.
Starting point is 00:53:22 Everybody else is running. And this is the way that cellular activity influences other cells and how metabolically healthy cells can become metabolically sick because they're an environment with other metabolically sick cells. And it's kind of analogous to this herd mentality. And maybe nothing that we can do would touch the entire system.
Starting point is 00:53:45 system simultaneously as things like heart coherence and getting our autonomic nervous system out of this sympathetic state into a parasympathetic state. You know, as a singular intervention, I can't think of anything that has more of a systemic effect and more of an immediate effect. Exactly. And one thing that I learned more and more about cell membrane medicine
Starting point is 00:54:09 is that cortisol especially push the body to producing phospholipase H. enzyme, which you like is a cell membrane. So the higher stress response you're dealing with affects a cell membrane, right? So like the works of Dr. Bruce Lipton, for instance, she talks a lot about the mindset and the feeling and how that affects the cellular health is all connected there. And it's really vital there. So one of the things that I do, obviously, we talked about the lipid membrane medicine. The first thing I help people to do is getting your circadian rhythm balanced. That's the first thing, right? So that light day-cycle aspect of it has to be
Starting point is 00:54:45 really dialed in. So I actually utilized an app called My Circadian. It was actually formed by my friend Sarah Kleiner. And that particular app tells you when the daylight, a daybreak is going be occurring to get that person out the door, getting that initial start of that blue light emitting from the sun. And the infrared. The infrared affects positive changes within the overall mitochondria function. And this is the first, what, 45 minutes isish? I would do about the Obviously, people have busy lives and, you know, have to have you take a family. I'm not saying 45 minutes outside. I'm saying within the first 45 minutes of the sun cresting their eyes and what they call first light.
Starting point is 00:55:21 I would recommend the first thing. So, for instance, like, we're in Miami, obviously. And the day break for this morning was at 6.45 a.m. So I usually like to go out between, you know, within the 10 minute window of that time. Okay. So start to getting that blue light emission there. Okay. So once you start having that blue light and that's first light, it actually helps to
Starting point is 00:55:42 lower cortisol response, right? Also helps with proper fatty S metabolism and metabolic process. But another thing that the sunlight does is, obviously, you know this, our mitochondria makes its own water. So that structural water that occurs in the cell. Gallons of it every day. Right. And that structure's structured water is a vital point in just doing cellular detox.
Starting point is 00:56:07 I wonder if the stress response increases the production of deuterium. It does. It does. It does. Because we know that destroys the crab cycle. Yeah. So, you know, sometimes that is very hard to discuss with clients, but I started using a company called light water. So you have five per person million.
Starting point is 00:56:26 It's one good thing to start with. You don't want to do too high of a due term depleted water too fast. I mean, that causes another level of issues because now you're dumping everything out. Right. So you've got to be very careful with that. Another water that I started using is Gerald Steiner. sparkling water at the supermarket. So the higher the altitude
Starting point is 00:56:46 were the water sourced, the lower the Deuterium State. Ah, I did not know that. Yeah, so that's really vital. Because Deuterium water is hard to get a hold of. There's like a place in, I want to say, Bucharest? Bucharest is one, but then also one part of Mexico, Tijuana.
Starting point is 00:57:00 Okay. There was a crater. I might be wrong on the location, but there was one part of Mexico where the meteorite hit that area. So that area is depleting. Deuterium depleted water source there. So a lot of these mitochondriacs apparently go down there and then.
Starting point is 00:57:20 Did you just make up a word? No, no, no, this is a term that... It's a term by Dr. Jack Cruz. I've heard of hypochondriacs. No, no, mitochondriacs. Monocondriacs, yeah. Dr. Jack Cruz, I mean, he's foremost in terms of looking at this whole, you know, cellular health and looking at circadian rhythm.
Starting point is 00:57:35 But, no, it's really the powerful part. Even, like, deuterium is very important to... When you... The study is out, also... So I think it was six weeks into drinking to tune depleted water was able to reverse type to diabetes. Yeah, no, I bred these studies. And due to your, you know,
Starting point is 00:57:53 our bodies make this intracellular water. And estimates are as high as 100 gallons a day. When you start telling people that you make 100 gallons of intracellular water every day, they go, that's impossible. I only drank half a gallon of water. We make it the same way we make it in space. You take two hydrogens, one oxygen,
Starting point is 00:58:08 you slap it together, you have a water molecule. So we're not capable of drinking enough water to feed our mitochondria. So we manufacture this from a gaseous state. And when you add this extra proton, it becomes heavy water or deuterium. And deuterium, when it enters the Krebs cycle, is like the Tasmanian devil. It breaks it.
Starting point is 00:58:30 And yeah, I've been talking about this and been a fan of it for a long time because and stress and other things, we produce a lot more deuterium water. There's a lot of evidence even that keto dieting of being in a ketotic state increases the production of deuterium depleted water. It does.
Starting point is 00:58:51 It does. And then certain things like seafood, for instance, like oysters, wild-caught fish. So the cold water fish and seafood are great for deuterium depleted food source. Eating things more seasonally, based on where you are, is really important there. So anytime we're working with these type of biotoxin clients,
Starting point is 00:59:08 you probably could ask about, diet is good for you. Paleo-based seasonal diet. Palliobase seasonal diet. Love that. The seasonal, why? Because depending on where you are, that sun codes a different message into the food. And that helps to empower your mitochondria to function well.
Starting point is 00:59:25 It's not about picking up avocado somewhere up in the North Pole. That's not what you want to do. Right, right. You don't want to eat banana in middle of winter either. That actually impacts more in the cellular function there. So you could do all the biohacking you want to do. It's fascinating how we were just... designed to be in sync with nature.
Starting point is 00:59:43 Yes. You know, and Western medicine has been using, or Eastern medicine has been using forest bathing and things for centuries, very effectively. And I always say if something has been around for centuries, like acupuncture or what have you, it's probably because it works, right? Things don't last 5,000 years that don't work.
Starting point is 01:00:01 And I think our reluctancy is to put our faith back in the basics, you know, very often because, you know, we believe a lot more in what man makes us than what God gave us. I mean, you even are a leading expert on drug-induced mitochondrial dysfunction, which I find a whole, should do a whole podcast on just that.
Starting point is 01:00:18 I want to finish the Encore method. Yeah. So we went through the environment, we went through the nervous system. Cellular health right now. Cellular health. So a big question about the circadian rhythm and why that's the important part.
Starting point is 01:00:27 Grounding is another thing that you could definitely do. Really impact. Love it. I'm being so vindicated right now. Yeah. So really impacting in terms of doing that. You're watching this?
Starting point is 01:00:34 Why? Because that overall grounding actually increased Vodox potential the cell membrane, right? So all those things there. So the neck, and then what we're doing that, we could incorporate doing like lipid membrane medicine. So phospholipidicid.
Starting point is 01:00:48 So body biopausea specific, I recommend all the time. I just take it prophylactically every morning. Yeah. You know. With that too, but when I work with clients with dealing with biotoxin issues, generally what I would recommend is around, you know, 10 to 15 ml or PC liquid from body bio.
Starting point is 01:01:03 Okay. So that's one of the vital thing. But when I work on cell membrane, I'm looking at in terms of how these biotoxins cause DNA damage. So DNA adduct we talked about. Right. And we talked about how buterate actually act as a chemical chaperone. And most of us are so muterate deficient. We're not getting enough fiber. We're not getting enough soluble fiber or insoluble fiber. And you could do a stool analysis to see that the short chain fatty acid production is down.
Starting point is 01:01:26 Keystone bacteria down. So all these things are affecting your butterate production. And butyrate is vital to protect your DNA. Not only about digestion, not about feeding your colonocytes, but really impact the DNA function. Correlated links to cancer or mind-numbing. Absolutely. And buterate also affecting positive change in your metabolic process, especially glucose, right? So GLP1s especially, right?
Starting point is 01:01:49 All those are things. But one of the thing about the DNA adduct I mentioned before is that these things like aflatoxin, even mercury, heavy metals, these things end up bind to the DNA structure, change the epigenetic of how the particular cell supposed to function. And these are the reason why the chronic disease states,
Starting point is 01:02:05 what butyrate does is, acts as a chemical chaperone, cleaves that off. And then you have phospholipid, like PC, for instance, comes in, sweeping that while helping to mend the actual cell membrane structure by adding in that. And this is where the other things, like bioactive oil, like balance oil from body bio, adding in linelake, which is omega-6, and alpha-limy, which is omega-3, help to restructure the cell membrane, adding in gamma-lilic, adding in gamma-lilic, like even in primrose oil, help to further decreasing the inflammation. pathway, right? Adding in things like especially pro-resolvent mediators, right? So SPM-based fissure is really vital there.
Starting point is 01:02:44 So body body value actually has a protocol resolving. And why am I adding SPM? Is that in the early stage of cell danger response, I mentioned about the ATP production is not there anymore. Right. What the mitochondria does is it dumps out that ATP out of the cell to act as
Starting point is 01:02:59 a extracellular ATP is something called a damp. It's a danger associated mediator property. PAMP's and PAMP. So that signals to all the cells that there's a danger going on. Well, the thing is everything in terms of the body is a frequency. We talk about herd mentality. Here's the
Starting point is 01:03:15 actual mechanism that it's creating. It's poisoning its environment. Yeah, exactly. So damp situation is unresolved issue that goes on. So what the body does is taking that extracellular ATP and then turns into SPM. Our body produces own special
Starting point is 01:03:32 pro-resolper meters, SPM, to shut that inflammation down. And, Oftentimes with an ongoing inflammation, that SPM reserve goes down. Right. So this is where getting proper, fresh cold water fish is very important. And it's adding into a particular diet, but I like to using SPM as an actual supplementation to resolving it. And then the other part that I mentioned before, the cell membrane and how the DNA adduct, well, these type of microtoxins also causes protein misfolding. When you have a protein misfolding, that in itself affects how the tissues and protein, are being synthesized.
Starting point is 01:04:07 So how do you resolve that? Adding in Tuttga, which is secondary bowel salt, relieves pressure on the endopoise reticulum as a de-stressor, but also helps to unfold the protein misfolding properly. So this is how you able to get the cellular impact damage from the mycotoxins there. So this is a really important. Then you start working on the optimizer detox pathway,
Starting point is 01:04:30 specifically gut function has to be number one. You've got to be established bowel flow as well. And mold and mycotoxins, it actually affects bioflow, specifically mold, for instance, like aflatoxin, I'm so okotoxin and chachythesans, for instance, those end up having to impact something called cytochrome 7A1. So I talked about the cytochrome P4503A4, well, there's a particular enzyme called 7A1, which is needed as a rate limiting step for bioproduction. Unfortunately, mold affects that. So it reduces the secretion of bile.
Starting point is 01:05:06 Production of bile, right? Production of bile. And then the other part is there's a transport chain called B-Sat, which is a bio-salt export pump. And that particular pump gets shut down by mycotoxin as well. So you cannot produce it, and you cannot even get the proper bowel flow going on. So this is where people cannot get to do the natural detox it looking to do.
Starting point is 01:05:28 Yeah. So this is why adding in... It's appearing fat metabolism and all kinds of... Correct. Even estrogen metabolism there. So like when you're doing a comprehensive stool analysis, I see that the person's beta group around this elevated. That's a number one sign that that's mold and there's a bowel flow that's affected.
Starting point is 01:05:42 So they're recirculating basically, retoxifying the entire body because of lack of bioflow happening. That makes so much sense. And then rebalancing the microbiome. My biome. So this is where the proper use of antifungals really important there. I mentioned about the spore-based probiotic, but antifungals, I would recommend decreasing the fungal overload in the body, then working on the mycotoxins.
Starting point is 01:06:02 And there are different herbals like golden thread, millia, all the different types of things, including olive leaf. And then the last part is the use of pharmaceuticals. And I don't say not to. I use it at the last. I'll recommend using itchiconod for
Starting point is 01:06:18 about two weeks just to get the internal condensation deal with mold permanently. And this is where oftentimes when I work with clients, about five to six months, they're able to reverse their microtoxin issues there. Unless they're dealing with hyposensitivity issues, but some of the minor non-complicated issues,
Starting point is 01:06:34 they tend to get to recover from mold and mycotoxysm within five to six months. That's fantastic. Yeah. Wow. I hope that you'll come back on the podcast again because I would love to do an entire deep dive on drug-induced mitochondrial dysfunction. I would love to. Because I think the leading scientists in longevity and aging now are inside the mitochondria.
Starting point is 01:06:59 We've actually found like the deepest tip of the root. And we understand that most of these bugs, mold, mycotoxins, parasites, viruses, heavy metals. At the end of the day, they are all disrupting this critical organelle. And the consequences of that are so vast. There's such a myriad of consequences. And even in the functional medicine space, we still do chase these consequences instead of getting deeper, deeper,
Starting point is 01:07:26 deeper down into the mitochondrial function. So I'd love to bring you back to even just, just do it a whole deep dive on that. May I have two things there? Yeah, of course. So one thing, you talked about the drug and just monocondyl dysfunthonction, is something that I'm always passionate about. I'm also passionate about phomachinomachy.
Starting point is 01:07:40 This is when I looked at the whole Sarticlean P-F50 enzyme structure. That's what your PhDs into. One of the things that was interesting when I was looking at the mycotoxin industry, we have some drugs out there that are derived from microtoxins. So there's a drug called mycopenolate. The brand name is called Celsept. They utilize a particular drug for kidney transline patient.
Starting point is 01:07:59 so that you don't have an organ rejection. Well, that microphenolate, that's a drug name, derived from mycopenic acid, which is a mycotoxin itself. Wow. So utilizing micro toxins to derive the particular medicine, that's how powerful these micro toxins are of causing immunosuppression.
Starting point is 01:08:19 Reason why a lot of times when you're seeing, I'm questioning there's parents out there listening, kids were dealing with constant strep issues, right? And colonization dealing with these things, they are derived from mold, especially aflatoxin, ochritotoxin causing that problem. When you're having chronic UTI issues also,
Starting point is 01:08:37 why? Because mold and mycotoxins unfortunately affect the mucosol lining of the bladder, right? And then you have a higher issue dealing with UTI. So why is that the woman dealing with chronic UTI issues? And they're trying to get through the rooter, they use multiple antibiotics and that can't do it, mycotoxins. Specifically citronin and okrotoxin.
Starting point is 01:08:57 Those are showing up on everybody's urine test. We do a lot of vibrant total toxicity testing, and that one is always pegged on there. And the second thing I want to add is that this is where the enhancing the resiliency part is coming. As you start to increase the redox potential in your cell membrane, a lot of issues deal with mold, parasites, and all these different bio-toxins is not of an issue anymore. Reason why is you built that cellular resiliency
Starting point is 01:09:26 and that negative ion charge and then the electric potential in the cell membrane, your body's mechanisms to repel those out. Unfortunately, we are losing that ability. And I strongly believe it's because of the environment's one thing,
Starting point is 01:09:42 but I think it's non-native EMF issues and blue light issues that's bombarding our entire system that the body doesn't have that. So this reason why when I work with clients and I jokingly say this, is that at some point, I don't want to ever see you again.
Starting point is 01:09:55 Yeah. Right. It's not because I don't like them. It's just that I want you to be self-reliant on yourself to be the right doctor. I want to empower you to be the best doctor for your own. And this is one thing that I'd like to teach. And this is the reason why Paul the Encore method is enhancing resiliency, cellular resiliency that is. Love that. Right. Love that. So I wind down all of my, we're going to go into my VIP group because these are the guys that I let know ahead of time who's coming on to the podcast. They know that you're coming on. They've got a holistic questions for you. So I want to get to my VIPs. But I always wind down on my podcast by asking every guest the same question, which is, what does it mean to you to be an ultimate human? There's no right or wrong answer to this, by the way. The ultimate human is to have cellular resiliency to live your full life to your potential that God has given you. Wow.
Starting point is 01:10:48 I love that. To have the cellular resiliency. Hear that, guys? The cellular resiliency. I love it. Thank you so much. Thank you very. Appreciate it.
Starting point is 01:10:57 It's been on the ultimate human podcast. I have a feeling that you're going to be a regular guest. Such a paucity of expertise in this area. And even though you provided the scientific background, I think you made it understandable for my audience. Thank you. And we deeply appreciate that. And guys, until next time, Esther Science.

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