The Ultimate Human with Gary Brecka - 35. The Future of Anti-Aging & Longevity with Dr. Rafael Gonzalez, PhD and JuveXO President, Brian Pla

Episode Date: February 13, 2024

Get weekly tips from Gary Brecka on how to optimize your health and lifestyle routines - go to https://www.theultimatehuman.com/ For more info on Gary, please click here: ⁠⁠https://linktr.ee/thegarybrecka ECHO GO PLUS HYDROGEN WATER BOTTLE https://echoh2o.com/?oid=19&affid=236 BODY HEALTH - USE CODE ULTIMATE10 for 10% OFF YOUR ORDER https://bodyhealth.com/ultimate What if slowing down aging was as simple as optimizing your diet and lifestyle? In this episode of The Ultimate Human Podcast, Gary Brecka interviews experts Dr. Rafael Gonzalez, PhD and Brian Pla about practical steps that anyone can take to slow cellular aging. Dr Gonzalez has been in the regenerative medicine field for more than 20 years and has several scientific publications with his focus being on maintaining a healthy immune system, and ways to slow down the biological clock both inside and out. Brian Pla entered the medical realm when he invested in multiple medical companies with a focus on pushing technology forward to have non-invasive and minimally-invasive procedures to lift and tighted skin. This conversation covers cutting edge treatments using stem cells and exosomes that are showing promise in clinical trials for rejuvenating skin and sharpening the immune system. Tune in to learn specific immune system markers you can test, the impact of fasting and food, and how exosomes may be the next revolution in anti-aging skincare products! 01:00 - Who are Brian Pla and Dr. Rafael Gonzalez? 02:45 - What are the top factors of anti-aging? 05:00 - How fasting slows down cell division. 08:15 - Why there isn’t one perfect diet and the one common factor of all of them. 09:30 - What are the impacts on the body when you fast? 11:00 - 3 key markers to know about your immune system. 12:15 - How to know which way of eating is ideal for you. 15:00 - Is there a positive impact to fasts longer than 3 days? 16:00 - How to get started with intermittent fasting. 17:30 - What is an exosome and how does it impact you? 21:30 - Where are exosomes used? 23:40 - How do they extract exosomes from umbilical cords? 31:30 - Can they control the age of the cell? 34:45 - What trials are being done to find more uses for exosomes? 36:20 - How JuveXO is finding ways to improve the immune system. 38:00 - What is causing the rise in auto-immune diseases? 41:00 - Why is the United States behind in anti-aging technology? 43:30 - What are the studies that they’re most excited about? (Cancer Research) 49:30 - Should new Moms freeze their child’s umbilical cord? 53:00 - What conditions allow you to apply for using your own stem cells? 55:30 - Top tips for getting started. Study Mentioned: Autologous NK cells propagated and activated ex vivo decrease senescence markers in human PBMCs Connect with JuveXO: ​​https://juvexo.com/ Gary Brecka: @garybrecka The Ultimate Human: @ultimatehumanpod Subscribe on YouTube: @ultimatehumanpodcast The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

They found a small lesion on my prostate. Getting cancer in a stage one versus a stage four? Uphill battle. Game changer. Game changer. All these thoughts come into your head like, oh my God, what does this mean? Is it cancer?

What do I do? I will not be caught off guard. One of the biggest things that we call are autoimmune diseases. And autoimmune diseases are on the rise. It's crazy. Yeah, they really are. It's crazy.

There's new ones popping up. We have multiple clinical studies on goal. Hopefully with the clinical studies, once it gets drug approval, we're pretty confident we're gonna get one of those across the goal line. What are some practical steps that they could take to slow down the biological clock?

But ultimately you look at the key thing to longevity is caloric restriction. And genetically tested them all the way through until they die. And we'll do this and people don't do this. Let's take a step back, grow it one more time. The aberration appears again. We'll say, uh-oh. Then we got to contact mom.

We have to contact dad. We need you to test baby. 100% of the time, there's something wrong. Wow. We predicted it. Hey guys, welcome back to the Ultimate Human Podcast. I'm your host, Gary Brekka, human biologist, where we go down the road of everything anti-aging, longevity, biohacking, and everything in between. And today we are going down the longevity and biohacking road

in a brand new direction. I've invited two guests onto the podcast today. I'm happy to call both of these guests close friends of mine. We've had a long working relationship. They're two of the most intelligent human beings in the entire industry. I can't wait to delve into the nuggets of wisdom that they're going to drop on the podcast today. First, Dr. Rafael Gonzalez, a PhD in anatomy and neurobiology. He spent the last 20 years in the sector of regenerative medicine and lately has had an intense focus on keeping a healthy immune system

and slowing down the biological clock, both inside and out. And I know all of you are interested in slowing down the biological clock. So stay tuned, maybe even take out a pen. And I've got Brian Pla,ow very good friend of mine he is the president of juvexo they are a manufacturer of exosomes and if you don't know what an exosome is then stay tuned because you're going to want to know what exosomes are you probably heard of

stem cells but the next generation of treatments in the biologic world is exosomes and they have so many uses that we're gonna go down the road of what we're using them for and how they might benefit you on your anti-aging longevity journey. So welcome to the podcast guys, Dr. Gonzalez. Great to see you again. Thank you very much, brother.

Pleasure. And a day at the office. Yeah, another day at the office. But what's been amazing about this journey, I kind of go around the world and I find all these anti-aging longevity, biohacking experts, but Dr. Gonzalez, you have kind of a unique expertise

in the world of biologics. So for those folks that are listening that don't know what biologics are, don't know the difference between a stem cell and an exosome, and certainly how these things might impact biological aging everybody's interested in healthy immune systems and and turning back the biological clock as you say both inside and out so tell me a little bit about what what can people do to turn back the biological clock

you can start off i mean you essentially know you can start off with the baby steps the stuff that you're doing right now, which is fantastic. You know, focusing on diet, focusing on, you know, specifically nutrition, because the only thing you have most control over is what you put in your mouth. You know, supplementation the right way, exercise. If you're able to exercise, exercise in the right way. There's so many, there's a ton of studies out there just focusing on what does exercise do? What does nutrition do? We've talked about before in the context of longevity, slowing down cells from dividing,

which is what's key to longevity. Slowing down cells from dividing is a key to longevity. Yep. Okay. So yeah, because if you think of, for instance, the day that you go and eat that delicious slice of pizza, what transpires when you have one slice of pizza and then don't you have the urge to have another slice of pizza the majority of times? And then your gut's on overdrive. What has to happen? Cells have to divide in the gut. Cells have to, you have that not only there, but metabolism starts playing in place the liver

now you have cells involved in the liver there's a lot of cells that have to come into play and ultimately what ends up happening is cells have to divide and when cells divide it causes aging remember every cell in our body only has a finite amount of divisions at one point they become what everybody calls a senescent cell or a zombie cell right occupy space cause havoc cause cancer autoimmune diseases all neurodegenerative diseases cardiovascular disease all this this is general aging right you slow down basically the cell division and you get to where so what is some practical way so so you know not eating

pizza and junk food fried foods you know high high glycemic carbohydrates processed foods i get that but if you're listening to this podcast and you're like how do i put a longevity plan in place for my nutrition or for my activities because i think there's so many options out there now. There's cold plunging, and there's red light, and there's oxygen, and there's, you know, half the, you know, internet is telling you to do cardio, half the internet is telling you to do weight training. Some say only carnivore, some say only raw food vegan, some say only vegetarian, some say paleo keto. What's your opinion on what an average person could do to slow down the biological clock? What are some practical steps that they could take to slow down the biological clock?

And then, of course, I want to get into some of the things that they have access to, maybe that are cutting edge in the stem cell and exosome world. I mean, one of the first and easiest things is fasting. We all know this. Because what happens when you fast is basically you slow down cell division the body just basically goes into a mode of wait a second i need to stop i need to slow down and i need to conserve and preserve what i have right now so what does that require it basically requires number one cells are not going to divide they're going to communicate with each other, which are exosomes, these bioactive

molecules, and they're going to basically say, whoa, wait a second, we're going into preservation mode, we're going to stop division. And another thing you look at in the context of aging is basically IGF, insulin growth growth factor which is also everybody knows that as you know for instance you can raise IGF using growth hormone but at the same time that causes excess cell division all the studies you're kind of borrowing from your future correct using to feel good now growth hormones you get this short-term benefit and you're just eventually the future is going to show up yes okay and you can no longer borrow you can no longer and at one point you can no longer borrow which is the key point of all of that yeah so slowing down cell division is number one number two is maintaining the key of everything

that is in our body what is everything formed when you put a piece of food in your mouth anything it doesn't matter what ultimately it all goes down to down to glucose. It's got to be formed consistently when you are basically breaking down food, no matter how you do it, whether it's, we talked about keto, whether it's vegetarian diet, whether it's a vegan diet, all of it ultimately forms one thing, glucose. Maintaining that glucose level is the key to success. Because when you have a spike- Maintaining it at the appropriate level. Correct.

When you have that spike, what transpires? Metabolism kicks in, cell division kicks in, and you have issues. So overall, you're a fan of lower glycemic diets, lower sugar diets. Correct. Maybe not necessarily being all keto for the rest of your life, but lower glycemic diets lower sugar diets right maybe not necessarily being all keto for the rest of your life but lower glycemic diets which you could accomplish with a vegetarian diet a vegan diet carnivore diet obviously a keto diet paleo diet so um so you would be less of a fan of following a diet category than maybe a diet strategy of just being low glycemic am i right

you're 100% on. And the other thing is no matter what, at some point you have to challenge the system. So all the studies that you look at of individuals that are over 100 years of age, all of them have one thing in common. They've all basically did some form of caloric restriction. Whether it be what we just discussed is basically it can be a keto diet, it can be even a diet, it can be even a low-carb diet as long as the carbs are correct. It can be a vegetarian diet. But

ultimately, you look at the key thing to longevity is caloric restriction. Okay. Because we did, I had about 50,000 people that joined me for a three-day water fast last month. You were actually a guest on the water fast. And we started talking about what happens in the body when you actually do a three-day water fast, when you actually deprive the body of food and people are like, I can't not eat for three days. And what was astounding was the vast majority of people, more than 90% of those 50,000 people made it all the way through the three-day water fast. And I tried to describe some of what was happening in the body. And we talked about cellular senescence, these zombie cells.

And is it appropriate to kind of say that the body eats itself from the weakest part forward? Is that a good analogy? Or how would you describe what happens when we go into a prolonged fast? And by prolonged fast, I'll just say three-day water fast, for example. Number one, for instance, is if you think of the cells, every cell in your body has some form of waste somewhere along the line. That waste will be consumed as energy. So that's a form of autophagy. So it's basically cleansing the system, cleaning the system of what's transpiring if you look at studies there's actually documented studies out

to there actually show that you can have cancer basically go on a fast and if you think about it it makes sense what does cancer feed on it feeds on sugar mmm it feeds on bad nutrition it's the number one consumer of your nutrition when you have cancer if you think of halt the eating what is it going to do you're going to starve that cancer you're going to slow down that progression because it's a shift in cellular metabolism right it's a healthy metabolic cell becoming a sick metabolic cell and i know that there's evidence that sick metabolic cells can actually go back to being healthy metabolic cells, where we can even get rid of these sick metabolic cells.

But what's making the decision? Is it the immune system that's going into the body and saying, okay, well, we don't have any food, so we don't have an external fuel source, so we gotta turn internally and we gotta figure out what we're gonna eat, and we gotta eat ourself. So who's making that decision? Is it the immune system?

One of the keys is the immune system. And there's probably nothing more important than that. That's our focus actually at our company is what we actually look at working on the immune system, maintaining immune health. Every single disease in the body has an immune component to it, has whether it be a pro-inflammatory or an anti-inflammatory component to it. Because if you look at the context of aging, all of it talks about what's called inflammation is when you're in a chronic inflammatory state, people that are obese, have a bunch of other diabetes, all these other comorbidities. Atherosclerosis or atherosclerosis. All these issues are essentially are in a chronic inflammatory state. And you look at specifically,

there's three key markers that you can actually look at. You look at HSCRP, you can look at TNF-alpha, which is one of the strongest controllers of the immune system, of the pro-inflammatory, that inflammatory immune system, and then you look at interleukin-6. Those are the three ones that you actually look at, and if those are elevated, you are at risk of having some form of cardiovascular disease, neurodegenerative disease, something that is in the context of aging. So somebody wrote those down and said, okay, I'm going to go talk to my doctor about looking at those three markers.

Would an average physician know that those three markers? They can send out panels for that, absolutely. And then you get that panel back and one or two or three of these are elevated. What's the action step you got to start off with number one we just talked about is what are you missing as far as supplementation what are you missing in your diet what are you taking the same diet's not equal for everybody everybody's completely different somebody can tolerate a vegetarian diet another one can tolerate a keto diet another can you know tolerate a vegan diet it just depends on the individuals

we're all unique and we have to find that's why a lot of the testing that you do will help find those parts. What is ideal for that individual to slow down that basically chronic inflammatory state and keep the immune system in check? Because if you don't keep the immune system in check, guess what? We're not talking about if you have a pro-inflammatory response, you're going to age, you're going to cause all these issues, which is called inflammation. But guess what? If you don't have that appropriate pro-inflammatory response, what happens?

The immune system can now pick up that mutated cell. So some inflammation is good because it actually allows the immune system to identify it. All cancer patients that we look at, guess what they have? An exhausted immune system. Really? Yep. They have an exhausted immune system and they have a really high profile of something called interleukin-10, which is an anti-inflammatory cytokine that helps keep it like,

I need to heal, I need to heal, I need to heal, I need to heal. But guess what? There's no attack. There is no killing transpiring what there's no attack there is no killing transpiring there's no pro-inflammatory response so the immune system doesn't really notice that this this metabolic shift has happened in these cells and it's sort of leaving these cells alone even though they're sick and or cancerous correct doesn't recognize them doesn't see them doesn't know how to kill them doesn't know how to attack it because it doesn't have a functional

immune system but we can sharpen that immune system by putting ourselves into a caloric deficit or doing um how how long if somebody's saying okay where would i get the biggest benefit 24 hour fast three day fast seven day fast um is there a difference between dry fasting and water fasting i can't imagine doing the dry fast first of all all. I couldn't either. I think, you know, just no water, no food. I mean, that's no nothing. I'm like, at least I can have black coffee and some spring water. And a bone broth. Yeah, and a bone broth on the first day. But, you know, again, when we did this three-day water fast, you know, I really wanted to introduce people to the simplicity of fasting and i think you know we looked at some of the

history of fasting every major religion in the world is fasted um or incorporates fasting catholicism um judaism buddhism you know muslims i mean they they all have some kind of fasting component and they fast for a couple of reasons one because they say it makes them sharper more attentive to god right they're able to have it so it's a spiritual reason but a lot of them you know also fast for health reasons right they get these health benefits so three-day fast versus a seven-day fast um you know are there major benefits to extending from three days to seven days? What's your opinion on that? My opinion is I think at some point you start wasting muscle. Okay. That's my personal opinion. I don't think it makes that much sense. I'm all about hormesis is basically challenging for a positive impact. So challenging the context of what we

talk about, cold plunge, infrared saunas, lights and fasting on a regular basis, whether it be actually just caloric restriction through fast mimicking diets, things that actually don't basically, you know, basically raise your glycemic index, things that don't cause basically cell proliferation, slow down the system and challenge it frequently. So you are a fan of intermittent fasting intermittent fasting um and what would you say is a good window 12 to 8 8 hours of a feeding window what's what's a good safe average window that somebody could use as an intermittent fasting guideline i think for somebody that's interested in doing long-term fasting the good start is you know, basically I would say 16 8

Okay is a good start. Okay to get used to it for a little while and then 16 hours of fasting eight hours of eating So 12 to 8 noon to 8 p.m. Yep Yeah, and I think also the the important thing about the fasting is keeping the body guessing, right? So it's not doing the same intermittent fast so i think one of the one of the one of the strategies also so you can maybe do four or five days of that a 16-8 and then do one full feast and one full famine right because the body's kind of you have a kind of guess yeah on what that on what that and that brings in that component of what they call metabolic flexibility right so you're not always

doing the same thing all the time so it doesn't get used to it, and you have some metabolic flexibility. So fasting and caloric restriction, one way to slow down aging, cellular division, autophagy, and maybe even take advantage of cellular senescence, meaning where we go in and actually consume the cells that might be sick or might make us sick, that metabolic shift where it's becoming a cancer cell. And if somebody wanted to take the next big step and said,

okay, I'm pretty woke to diet, exercise, fasting, what are some other roads that I could go down? I know that you guys are very well-versed in the stem cell and the exosome world, and I'm fascinated by exosomes. So, I mean, what is an exosome? I mean, for those of you who have never even heard that term, what is an exosome? Why should we be thinking about it? An exosome is, so if you think of it,

it's one 1,000th the size of the cells. It's a nanoparticle, so it's secreted by the stem cell. And what we feel, as we know, a stem cell is an undifferentiated cell that is releasing the exosome and is sending that message to a damaged cell to basically do what it has to do to right itself. So what we're seeing is that the exosomes now are carrying this. And kind of the way that our science works is that we're not just a pure exosome product. I like to use the analogy, right? If I'm putting a soccer jersey

on and i'm putting you in a soccer field you're going to play soccer so we're conditioning the exosome to do perform a particular function and in this case we're promoting it for cosmetic purposes so our exomes are very rich in hyaluronic acid collagen type 1 type 3 elastin growth factors and it secretes a peptide which from those of you in the biohacking world is called ll37 which is a big uh antibacterial antimicrobial which is one of the reasons we feel works very well on things like acne and and and that type of blemishes actually well and blemishes of the skin also so you can you you you um so you you take these exosomes you spray them on you put them in creams do you microneedle them like What can you do to put them into the skin?

We can deliver them in a variety of ways. In fact, my joke is if I was going to have a third kid, I'd call him exosome because I'm just so excited about that. We were calling it for a while in the lab, we were calling it liquid gold because we didn't have a name for it. I think we're seeing the exosomes have gotten, have gotten more mainstream, but we didn't just jump into the space. We evolved into the exosome space because of our extensive history of stem cell research and the great science that this man has done. So we just took a product that was a by-product and for a while they thought exosomes was garbage. There was no value in it. And we came to see in time that it's extremely valuable. Potentially it's the whole reason the stem cell

works is because the exosomes carry the correct correct message well i know a lot of times when you have an inflamed cell for example um you know you bring nutrients and other things to the wall of that cell it doesn't let it in you know it's almost like having a heart attack on the floor with the paramedics locked outside your door right their proximity doesn't matter but an exosome being roughly the size of a virus a thousandth the size of a cell, it would just pass right through the cell wall, right? So it can carry growth factors and hyaluronic acid into the cell. Well, basically it binds, exactly what you just said.

So if an area is inflamed, everything in our system sort of works as a lock and key system. There's a complementary sequence on a lock and key. It's actually a ligand and a receptor. Ligand, let's say, is the key. The receptor is the lock, and then what it normally does is actually binds to a receptor on the outside, and then it'll either internalize it, and it'll take that message into the cell, and it'll tell the cell, produce XYZ. For instance, let's just say, I need you to produce hyaluronic acid, I need you to produce collagen in the context of what we're doing for skincare do that but priming them to force that outside because there's not enough evidence out there

you know on basically collagen collagen is the most abundant protein in your body there is nothing more important in your body i mean this 3d that we live in is primarily collagen okay yeah it's crazy i mean it's just a crazy thing to think about. And secondarily to that, you think of hyaluronic acid. It's the second most abundant that you'll actually see in your body too. Really? Even though it's not a protein, but it's still the second most abundant thing that you actually see in your body. So it's really, really important.

I mean, all your joints are full of hyaluronic acid. It's what actually causes the cushioning the ability to you know to maintain the fluidousness in the joint the movement all of it yeah yeah it's exactly it's a wd40 of our joints is it true that hyaluronic acid holds 1 000 times its weight in water i read that somewhere but i wasn't in a peer-reviewed journal it's there's different forms of it the high molecular weight one will will okay yes so it's it's a. So it's massive. So obviously if you put this onto the skin, right, then it's going to help the skin stay moisture. Yep.

Correct. Okay. And back to the question you're saying, how do you apply it? So we could get it. The idea is to make injuries to the skin. So we could do it via microneedling. We could do it via thermal devices, you know, some machines like Morpheus, ablative lasers, kind of to create that injury to the skin to help the exosomes penetrate to get down to where they need to get to. Okay.

So you create controlled trauma. Correct. And then you put exosomes onto the skin. And when it heals, it heals. Yeah. And it's amazing the amount of downtime that it minimizes when you're seeing, you know, usually when you've done, you've seen traditionally you're doing a microneedling or a laser procedure you're really red for for a while i remember what was kim kardashian's famous like vampire facial that went so viral because it looked like your face had been burned into fire and then like you know and then of

course it looked beautiful afterwards but um so you know that was what massive microneedling. That was actually with TRP. So that's kind of yesterday. Correct. That's Atari. And so now, could you take your... We're now on PlayStation. Uh-oh, Rafael made a funny. The scientist made a funny.

He's not just smart. He's also funny. But yeah, we've moved on you know we moved on on on that front and and now like i said it's become so mainstream and also you know what we're seeing in hair and you know i know for many years you would see that commercial you're like i'm not only the hair club president i'm also a member right i mean i've actually and there's nothing that i won't try myself and so we came out you know he came out with a new a new version with uh recombinant hair proteins.

And what we're seeing is like, gee, a pet. You see it in that sense and how it's being applied. So a lot of these doctors are turning on to it and seeing how now we're regenerating without the use of drugs. Hair follicles and thickness. So, you know, where my mind goes is like, okay, well, you say that these things come from stem cells. First of all, where do the stem cells come from? Great question. Because stem cells contain DNA, right?

But exosomes don't, right? You can remove the DNA. Okay. So, you know, my first question is, where do they come from? Are they safe? You know, if they came from another human being, how do I know I'm not getting what they had? Right. And are they legal? I mean not getting what they had? Right.

And are they legal? I mean, are they FDA controlled? Are they done in still laboratories? Cosmetic use. Walk me through the process. So cosmetic use, anything, if you use for topical use, it's just a cosmetic use and that's about it. It's just used topically, sprayed on.

But where do they come from? Talk about the source, the stem cells, and how important it is. How do we get an exosome well an exosome comes from any cell in the body if you think of the simple thing of what we talked about that slice of pizza giving you a stomach ache and then you feel like crap because your head hurts and etc how did that signal get from the gut to the brain it's that neural access that we actually have. And basically, it's a communication that's basically gone from here to there. It's a protected communication. Similarly to you think of you need more testosterone in the testes.

A lot of times, you know, the pituitary gland signals all the way from the pituitary all the way down. It's protected. It's protected. Every cell in your body actually has an exosome, produces an exosome. Okay. So they have to produce an exosome to talk to their neighbors. Cells like to be in homeostasis, be happy, be feeling well on a consistent basis. How do they do that?

Is by communicating with each other and exchanging needs. So if I need, you know, Gary, give me a hand. I need some help picking up this package. It's similarly what transpires actually in our bodies with cells. I need, you know, Gary, give me a hand. I need some help picking up this package. It's similarly what transpires actually in our bodies with cells. I need help. I want to stay alive and I want to be happy and healthy. Okay. And the exosome is what does that with every cell in the body.

So my question is, where do, if they're derived from a stem cell, where you get the stem cell oh that's a great question the exosome like what's that process right so the process that we've undergone has been arduous and very very lengthy and essentially what we looked at we spent years in probably about it was like 2007 2008 studying all the different types of stem cells so we have stem cells from fat in our body we have stem cells from bone marrow body uh body. We have brain stem cells. We just talked about earlier about placenta. Hey, yeah, placental stem cells, amniotic stem cells. But what we try to look at was what is the most abundant, number one, and think of what transpires when a mom has a baby. So you have the umbilical cord. The umbilical cord is the best that's out there. The reason reason why if you

think about this logically what does it do it's the conduit of life right it's basically what supplies the correct nutrients from mom to baby not only that if you think about it logically how is it possible that dad's DNA is in there and it's able and the baby's not rejected it's because the immune factors that can help it so it's not rejected so it basically suppresses an immune response that transpires so the baby's getting nutrients from mob that also contains dad's dna wow so this conduit of life is full of essentially life. And it's mostly composed of, you think it's a hard rope.

For those women that have had babies, you've seen this. For dads like us that we've actually cut the cord. You say, how hard is it to cut that thing? You're like, whoa, what the hell is going on here? It's mostly hyaluronic acid. But they give you bad scissors sometimes. So you harvest the placenta, right? We harvest the cord. Oh, the cord.

We don't use the placenta because the placenta is a filter. Okay. So we avoid the placenta because it's a filter. It filters out anything that's bad. That's why we avoid that. Okay. The amniotic fluid and the amnion. The amniotic is basically the amnion itself has mostly epithelial cells.

It's also somewhat of a barrier and a filter. And then the amniotic fluid contains, mostly if you think about what it's supposed to contain, it a bunch of antibodies right is what it mostly contains wow so it helps with all the cushioning the cord itself is the conduit basically of life and all the nutrients most majority of all the nutrients we harvest the cord itself and our technology we spend years developing this technology we actually have clinical studies actually here in the united states and we license this this technology to an outside entity in Mexico that does some of these therapies too. And we just take a section of cord this big and it's all about the diet. What we

ended up doing was putting these pieces of this cord and we call it- You mean the diet that you're going to put the stem cells in? That we're going to put, that we feed the cells. So that they grow, so they expand the right way. So when you look at science and for those that know cell culture those those that know science well is what they would normally feed cells and all cell types skin cells liver cells that we would grow up artificially that we grow up in petri dishes they normally feed them a high glucose diet and the reason being is and you'll see this in culture which is pretty neat these cells will multiply like this you're just feeding them sugar and they're multiplying, multiplying, multiplying. You got the cells that you want. But what we did was looked at various different formulations of how do we slow

down the aging process of the cells. And what we looked at is looking at telomeres in the cells. And for those that don't know what telomeres are, it's essentially, these are basically like the ends of the shoelaces on DNA. Yeah, they're just caps on the outside of it. Yeah. And then they unwind as a cell divides and they're cleaved. A certain amount of base pairs are cleaved and then they're rewound. And with time, your telomeres shorten. And then at some point, your telomeres are so short that you have something called critically short telomeres and your age. You have neurodegenerative disease heart failure all these different diseases of aging we looked at that carefully and looked at how our cells age have them guess what diet the cells uh keto keto low glucose and we even put stem cells on a keto diet? We put them on, yes.

We put them on somewhat of a caloric-restricted diet and on a keto diet. And it ain't cheap. Very, very low glucose, and it ain't cheap. That's the thing. And we ran various different formulas, and then we looked at, especially in the context of the exosomes of what they're releasing, is how do we get them to release out more hyaluronic acid? The crazy thing is that you would see, like, you know, diabetics or individuals like us are looking at, what they're releasing is how do we get them to release out more hyaluronic acid?

The crazy thing is that you would see like, you know, diabetics or individuals like us are looking at what happens when I eat a food? Let me check my glucose. Let me check my ketosis. We were doing this in culture and looking to make sure that the food was optimal, that there's no spike in glucose, looking at glucose, looking at ketosis from a stem cell to produce that product. then we actually went above that and actually worked with a group a group at cleveland clinic started measuring ha for us we wanted to make sure that we have high molecular weight ha we don't want the low one

because that degrades high molecular weight hyaluronic acid hyaluronic acid correct and we achieved it that's where we captured that product and then we put it in a phenomenal amino acid blend that works fantastic and it maintains it really well and we maintain it frozen so you you harvest the stem cell from the from the placenta then you take this from the umbilical cord and then you um we put that in in a culture to grow it and it's growing on a keto diet so it must be it's under a certain type of stress that That stress produces high molecular weight, hyaluronic acid, which is great for the skin. Yes.

Growth factors. And then you take the exosomes from that media. We take all of it. Oh, you take all of it. We take all of it, because it's not only exosomes. Cells also basically secrete out, and we actually call it a secretome. Ah.

So they secrete out different things the 3d matrix how do you think the 3d matrix is produced you have cells everywhere they're all bound together they're all happy and then there's a 3d matrix that's produced a lot of that stuff is just secreted out and it's actually produced so we take that but not only that we've taken it a step further when is your skin besides when you're a baby when does your skin look fantastic when you're like 15 years of age age the cells that we produce we have evidence are about 15 years of biological age wow that's when we capture those signals so then you stop them there and what freeze them what do you do we correct we freeze them okay and then and then somebody would take that

vial of exosomes and microneedle it into their face for example and then that's going to help right the practitioner will apply we've looked at for instance even the donors that we have completely viral free no epstein-barr virus that's 85 percent of the patient population no cytomegalovirus that's about 80 percent of the world population too uh actually taking the cells before we actually expanded them massively and genetically tested them all the way through until they die, until they aged, to make sure there's no chromosomal aberrations. You'll be surprised how many cords we've actually gotten

and we'll do this and people don't do this. And then all of a sudden we'll get an aberration and we'll say, uh-oh, let's take a step back, grow it one more time, the aberration appears again. Then we gotta contact mom, we have to contact dad. We need you to test baby 100% of the time there's something wrong Wow. Yeah, which is pretty crazy. We predicted it Yeah Wow, we have and we've actually helped mothers with this because now the moms know what they and the dads know what they need to

Do you know they got to be prepared for instance? We've seen cases of Turner syndrome, an extra X chromosome, which is rare for a baby actually to be born like that, but we've seen cases of that. But guess what, when the baby now goes through development, they know that they're gonna start seeing the baby's not growing as much, the ears might look unusual,

the jaw and the head actually starts looking, they now have to put them on hormone replacement, they have to put them on specific medications to make sure they develop normally. Wow. So it's a pretty neat thing to find. And this is all just in the process of extracting exosomes, so you can use them topically.

So now, so I think what we're trying to do is create that appreciation where everyone's trying to see from the exosome, but the process really starts at the stem cell front, and no one's asking, hey, where's the source? What have you done to test the source of these stem cells that create these things? It seems like some articles asking, is there any way to test if the host has been vaccinated?

Does that have an impact or not? Well, you can mention the cell lines. A lot of people are asking that about stem cells. The three cells, so we have three qualified cell lines that we actually use. They were prior to COVID, any form of COVID. And from those three cell lines, we can actually produce one million doses of 100 million cells that are 15 years of biological age

wow trillions of cells so all of all of this even though you're culturing these things and you're expanding these things they don't lose their viability for lack of better word they don't we freeze them in specific formulations we've even i mean we we go down to how do we keep them maintain them frozen in that chronological state what do we use what formulations were best what is the best way to thaw them out you know how do we displace basically the dimethyl sulfoxide that's actually put into it that displaces the water correctly how do we thaw them correctly how do we maintain them after correctly what types of formulations everything the feeding the before and after all of it falling freezing to make sure that they're healthy vibrant cells that work well

so somebody that's on this anti-aging longevity journey you know caloric restriction um clean you know clean dieting intermittent fasting maybe even a few times a year prolonged fast um if they're really interested in their skin collagen lasting fiber and improving the tone and texture of their skin exosomes applied topically you think is the next revolution of of of skin care as long as it's the right exosome right and and where else you know down the road 10 years from now because i know you have several clinical trials underway here in here in the states where are we going to start to see exosomes and stem cells in the world of longevity aging you know bio-optimization where are we going

to see that in 10 years because i know there's restrictions right now you know well i think the idea is hopefully with the clinical studies we have multiple clinical studies ongoing so okay we're pretty confident we're going to get one of those across the goal line so what happens is that once it gets drug approval then kind of like drugs like a Viagra, right, you're able to use it off-label potentially for other benefits. And since we've already seen so much of those anti-aging and mitigation of chronic inflammation, we're very confident that we'll be able to see that more.

And the idea is to have off-the-shelf stem cells, not stem cells that you're getting from someone for as young as as we may be that that is that are older in quality right right yeah yeah cuz I mean our stem cells are the same age as we are right yeah um and so down the road we could see this branch into things like looking at treating the inflammatory conditions ago with aging correct you call inflammation yeah one of the key things that we actually learned with one of the studies that we actually did was we know that our cells the cells that we use can help regulate the immune system and if you think of which is what

something is there's nothing more important than that and when we talk about that you talk about remember you have an immediate immune response which is nk cells natural killer cells which we'll talk about in a little bit yeah macrophages neutrophils a bunch of some other cell types dendritic cells which is a fantastic cell that presents and basically orchestrates the entire army but the secondary the strong massive response is t cells and b cells but t cells either can be a pro-inflammatory cell a regulatory cell a suppressor cell or an anti-inflammatory cell. One of the most important ones is that regulatory one. Why? Because what does it do? We talked about we have to have that balance. It regulates that balance. If there's too much inflammation, which you don't want too much

inflammation, it'll regulate it and basically cause it to come down and cause the anti-inflammatory response to come up. Wow. So help regulate it. So it's so important to keep the system regulated because if it's not, guess what? One of the biggest things that we target are autoimmune diseases. And autoimmune diseases are on the rise. It's crazy. It's crazy.

There's new ones popping up. There's over 100 autoimmune diseases. And it's a crazy number. There's over 100 of them. And there's new ones that pop up. And what do you credit that to? Pesticides, herbicides, insecticides? What is it about modern day living?

Because as somebody that studied mortality for decades, this is the first decade of our measured lifetime where life expectancy is going backwards. We've never had a decade where mortality tables are actually taking life expectancy backwards. What are causing this sudden rise in autoimmune conditions? I think we're seeing it. We're getting bombarded from all sides, right?

It's in our water, right? We're seeing the microplastics and all the toxins in our water. Talk about that. Yeah. We're seeing it in our air, right? We're seeing it in our food source significantly. I mean, look at what a good job you do at kind of relaying the message. We're even organic.

I mean, what is really organic? How can you really vet? Like we can do more vetting on our stem cells than you can on your organic food. Yeah. You know, to that level, right? But no one's really testing that stuff. So if we're being bombarded, we can only do the best job possible. But it's mitigating all of those environmental factors.

And we feel that ultimately, I think you touched on it earlier, which is the diagnostic testing, right? So we have to go back to what is the source. Some people may be more sensitive to particular toxins than others, right? So if you run heavy metal toxin panels, you're testing for microplastics, you're testing for, you know, molds, and you get a very wide panorama of what's going on with a patient, you're trying to identify two things. What are their deficiencies and what are their goals? And you're not going to be able to fix either if you're not removing the source. So we have to get to the source first, because the best stem cell, the best exosome, the best keto diet will only do so much if the ground is polluted, right? And if you think of our computer, I always love to give this analogy, right? Where our computer over time starts to slow down, right?

Because what happens? We keep putting more and more and more crap into it. So it starts accumulating, the cache starts to build up. So sometimes you take it in and just by clearing cache, removing the source of the clogging is sufficient for that computer to speed up. So it goes back to, that goes back to the fasting thing. So what are some other things that we can do to improve the immune system and slow down the

biological clock oh one key thing is you talk about it every morning sunlight wow vitamin d i mean that's like one of the nice to have a phd back me up on sunlight there's nothing but there's really nothing more important than that because go i mean going even going back to that the question is viruses we've now been challenged with another virus we're now going to be challenged soon probably with another virus that's coming on horizon and the immune system gets tapped you have to you know diet supplementation is important people are like oh well wait a second there's i don't know how many people you've probably seen a ton of people i spend all day in the sunlight and then you go

test them they're vitamin deficient yeah they're vitamin d deficient right it's because you're not absorbing your gut's not working correctly you have gut issues you got to fix you got to fix the source what you just said yeah find a way to fix the source so you can absorb those things and if you can't absorb them correctly hey do an iv right of you know go get some vitamin d supplementation or whatever iv nutrition to make sure that you're getting the right supplements into you yeah i i'm a huge believer in targeted supplementation so we have you know fasting um exosomes for topical skin we know that um aging is an inflammatory condition, inflammation, caloric restriction, you know, non-processed diets.

But now this world of biologics, stem cells and exosome, which I think is advanced more outside of the US, right, than it has in the US. 100%. Is that just be the regulatory framework? Regulatory environment here in the United States makes it difficult to do work here.

And many countries out there are allowing stem cells. They're regulated in other countries. You know, we actually gave our license to a place in Mexico, in Cancun, one soon to be in Kabul, that actually works with the cells that we actually use. And people think, you know, first of all, where do you go on vacation people talk about i'm going on vacation to cancun i mean it's you know then some people say well wait a second it's not safe no detroit is not safe and many places or many places portland oregon is not very safe right now there's a lot of places that are not really safe you know in the united states they're not really talking about these type of things yeah but people go consistently there's millions and millions of tourists that go hang

out on the beach and it's really not third world there and i know for fact and i mean i've taken so many people and we've gone down there to look at facilities and they'll be like wow these are state-of-the-art facilities uh we got one of the original guys that has started working some of the first MRIs. He went down there and he was like, why do these guys have, you know, a $2 million piece of equipment here in this hospital? A complete change of perspective. They see me, they don't see me in the U.S. And it really changes that dynamic. I know medical tourism is big down there.

Yeah. And the vast majority of the doctors over there are american trained they've done some form of you know postdoctoral training some form of you know official training in the united states speak perfect english they know everything they actually collaborate with american doctors on a consistent basis so it's not like you're going to you know people think oh it's third world why would i go there for medical tourism because guess what a lot of stuff is we see a lot of these stem cell clinics cancun columbia panama i mean they're they're in in other countries but pretty renowned people go down there and get these these treatments i mean so if we were to peek behind the curtain

a little bit and say what is what is some of the most promising, prolific research that you're doing that you think will be on the horizon? I mean, whether it's on improving the immune system, whether it's on stem cells, you either have to get it done outside the country, or maybe it's gonna be available here in the States in five years or 10 years.

What's some of the most promising, like what makes, what blows your mind and gives you that Perry Mason moment, like, ta-da this is freaking awesome we just used ourselves with the perry mason yeah yeah oh you did you did we we published a paper in end of 2022 of something that we spent eight years studying and it's senescence the zombie cells and if anybody looks up natural killer cells you'll type these things are these are the first responder to a virus to a mutated cell and then to a senescent cell this is not a cell which is a potential cancer cancer cell okay the first responders and then case is this unfortunately as you age these

things also age and they're no longer natural killers they're dormant office workers government workers whatever you want to call them I don't know but they're not they're not doing what they need to do they're not washed up police officer no gun whatever yeah can't do anything yeah okay so these guys these are the navy seals of the white blood cells okay these are the guys that come in attack target kill and we actually took the line of everybody looks at cancer in the context of natural killer cells. We looked at senescence in natural killer cells. We were the first to look at senescence in natural killer cells.

We published a paper last year, we actually got a patent on it about a year and a half ago. I read that paper. On this too. And what we showed is we can remove senescence in the immune system. But if people think about this. Wow, meaning the zombie cells of the immune system yeah and you do that by turning the immune system safely on itself like what removes those cells the natural

killer so we take natural killer cells from you we will actually grow them up activate them then put them back into you and they will remove senescence hmm they will target and kill senescence we can lower that senescence but then people think so what you lower the senescence what happens well guess what you now have the right signals because you only have a certain amount of cells in your body the signals in the bone marrow now are saying i need to release fresh healthy cells in there senescence isn't consistently happening yeah because when you remove cells you know red blood cells from the bloodstream the bone marrow replaces those red

blood cells so you're saying that if i remove senescent immune cells like dysfunctional sick old tired non-functioning immune cells i'm going to replace them with healthy functioning immune cells sort of rewind the immune system two to three billion i mean if you if you think of every day every single day we lose over 300 billion cells that's a crazy number every single day it's mostly red blood cells but it's still it's a lot of cells and your system just turns them over and produces new ones right this is going to be similar to you remove that and now the system has to regenerate and ultimately this actually started off with in 2010 it was a publication that came out that they essentially took a senescent mouse model

and they took that senescent mouse model that couldn't walk the maze had no hair had no muscle then they took a healthy one and they basically that's just an old mouse and it's it's a model it's a knockout model that basically has a gene missing that causes it to be senesced ah okay then they actually took a healthy version connected to it and then they know i read something about this yes so it's a memory it's it's an experiment that they connected to and what this mouse that was unhealthy grew hair, grew muscle, was able to walk the maze after, basically got younger. When they went back and looked at what had transpired with the organs and everything is the senescence was gone.

Wow. And the mouse naturally regenerated. The mouse that was healthy, its immune system went in and fixed the sick mouse is that essentially what happened wow yeah is that why brian johnson is putting his son's blood into his body did you hear about that that's plasma yeah he's using the plasma proteins yeah there's evidence that actually plasma works well too okay yeah so i wanted to ask you a question obviously if i would have told you this is my podcast dude i'll ask the questions but if i would have told you you had to wait look at how much good you've done how many people you've gotten your message oh stop no no no but listen what i'm

getting is that imagine if i told you you had to wait eight years ten years to see the results of that you would have said no way i'm not getting into this. So that's what happens with the traditional drug route. So if we have to wait that amount of time to get some of these things across the goal line, then we're in this, we're passionate, we wanna help people just like you. And so being able to have these licensees technologies outside the US, they could get these treatments to people,

we're changing lives every day. So those are the kinds of things that are available outside the country. You can go to Cancun, rewind your immune system, you can get some of these biologic treatments. I mean, I think it's just fascinating because what's interesting about all of this science is that we're actually just finding ways to enhance the body's ability to do what it does best exactly which is a really interesting thing that continues to strike me being in this industry and in this business is that a lot of the science seems to be coming full circle and we're not like looking at chemicals and synthetics and pharmaceuticals we're actually

looking at how do we better tap into the body's resources to heal itself right you know so platelet rich plasma prp most people have heard of, putting it in knees and hips and shoulders and joints to kind of accelerate healing. Now you're talking about taking exosomes from stem cells, putting them back into the skin to regenerate the skin, maybe even using our own stem cells. What about all those people that have,

all those moms that froze their cord when they gave birth five ten years ago when they started freezing the court is there a possibility they can unfreeze those and and get stem cells from those i mean they're the promising treatments with those kinds of things i people ask me all the time i mean well i mean the context i think it's fear based like yeah oh shoot i should i'm having a baby i should freeze the cord um but let me tell you it's smart it is because it is let me tell you, it's smart. It is. Because it is smart.

And the reason why it's smart is because you never know. Your baby can be born with a blood deficiency, a cancer, or it can happen within six months, a year, whatever it may be. Due to who knows, you don't know. A genetic that's gone bad. And it can happen. And it gives you, it affords you the opportunity to have something there that's naive, that God forbid your child has to basically, get chemotherapy, get radiation.

We can now rebuild that blood system to make it healthy. So you're a fan of mothers if they can. But there is a caveat. Freezing, but there's a caveat. There's a caveat to it because it only works up until a certain amount of weight. There's a formula to reconstitute the blood system. So once a child hits about five years of age, that formula no longer works, and you basically have to find other units and other matches.

You have to find what's called the compatibility matches to actually do it. If your child is 10, 12, 15, you might need three units. You might need four units. You have to dig outside to find matches. I got you. Yeah, and you also cannot ask wherever it's being held, hey, could you just send me back the cells and I'll take care of it? It has to be for a range of conditions that are approved by the FDA for that.

Blood conditions, correct. And it'll never be shipped to you as the client. It'll be shipped to a medical facility only under one of those conditions. So it's very important to understand that. Anything outside of that, you will not be able to use it. And as Dr. Gonzalez said,

after a certain age, it's also not sufficient because they're not expanded cells. It's only the, I mean, you're really only collecting about six inches worth of of cord or blood but they can't and they can't unfreeze that and send it to a lab and expand it no no those cells those are basically the blood stem cells yeah there you go no no it's crazy talk i mean wow we just talk

about expanding cells then i asked about that but that's like i just dropped a fart in a room or something like whoa blasphemous how dare that that's crazy talk it's it's a different stem cell and that's where people get confused ah it's a blood stem cell and blood stem cells nobody has really successfully been able to expand the blood stem cell which is actually the mother stem cell they call it the mother stem cell it's floating in your bone marrow we have them in our bone marrow and then they actually circulate outside our body it's crazy because if you think of there's evidence of patients that have cardiovascular issues they have more stem cells floating in their system than we do if you're healthy and why if you think about is the body wants to repair itself but the signal's not there to make that repair you know because if you would think that it would repair itself then all

you would do is there's a drug that you can take snupegin you can actually treat stimulate the bone marrow to secrete out all these progenitors and stem cells into circulatory system and there's been a study done on that the heart should heal right doesn't heal wow and why is that signals the signals not there the signals for the stem cell to recognize to say i need to make the change to you know to increase vascular church or release the right exosomes, to make the right changes that are needed to help heal the heart are not there. Right. So then, you know, somebody that's on this anti-aging, this longevity journey, you know, they're really, there's a lot of topical skin kind of options available for them but if they really want to look at improving the immune system or exploring stem cell therapies they really got to go outside the u.s i would

suggest it okay that's good because even stem cells from yourself what the second you try to use it systemically it's it's also considered a drug anyways i say so you would not be able to apply it that way because they can they can get stem cells from your fat right they can get stem cells from your bone marrow they do bone marrow aspiration it's a small amount though yeah right it's but as for the fda guideline it's it the cells there's three real um kind of conditions that you could use it has to be homologous which is same type of use that the cells were doing before they got pulled out it has to be autologous from yourself and then minimal manipulation. You cannot manipulate the cell in any way, shape, or form.

And if those three caveats are met, you could apply it. If I've got a bad knee, can I take stem cells from my hip and put them in the rest of your knee? Is there any benefit to doing that? There's definitely benefit. It's a trick question. I know that there is. I'm asking for the audience.

There is benefit. But you have to think of it as, once again, they use that key term stem cell. they use that key term exosome but what you're really getting is a needle in a haystack but ultimately you look at the factors that are contained in that needle in the haystack because there's growth factors in there you know for instance if you look at bone marrow you extract bone marrow out and the percentage of you know you have a glass of bone marrow and that glass of bone marrow the percentage of stem cells you were having there for an average 40 year old person is going to be point zero zero zero zero zero one percent of

stem cell of stem cells if I pulled in the bone marrow in a glass of bone marrow that's that's how much stem cells you'd have in there. Wow. It's like what we... So what is the benefit of tapping my bone marrow and doing bone marrow aspiration and putting it into my joint? The thing is that there's other cells there. So you have immune cells there, you have naive immune cells there, you have an endothelial

cell, that's actually the cell that lines the vasculature. And all those have proliferative effects. They have healing effects that can actually work too okay even though there may not be that many stem cells but there's factors in there that can help heal okay beautiful well guys that is fascinating the discussion i mean i think that um this whole world of biologic stem cells exosomes to me is like the new frontier just i wish we could accelerate it you know um somehow but um just in in in summary like what are some of the key takeaways you know you you speak a lot about fasting you speak on um you know improving the

immune system you speak on rewinding the biological clock what are the big takeaways that you want people to know if they're interested in longevity quote-unquote anti-aging bio-optimization um what are the key takeaways you want them to have to for for me personally life i mean for me personally it's number one think about what you put in your mouth because even individuals that go get any form of cell therapy i say you you're basically putting a bandaid on an issue that you've never solved. Get yourself healthy, because guess what? If you're going to put a cell into an area that's not healthy, cells are going to die. Yeah.

I mean, these things people think like, oh, it's going to go inside of me. It's going to regenerate all this. No, it does not. It only lasts a certain amount of time. It gets lost in the inflammation and everything else. And your own immune system will eat it up and remove it get yourself healthy first then go get that done because essentially what you're doing is investing in yourself it's not cheap yeah i agree yeah and i would just add you know you know with all the precision and advanced diagnostics is get a wide diagnostic testing, right? Like I said, from the blood work

to the, you know, gut health, the gut's huge, right? As you said many times, a big percentage of our immune systems in our gut. If that's off, I mean, you've even spoken about, you know, the dopamine release, right? And the benefits of that. So 70%, get your gut right, do the advanced diagnostics. I mean, there's now companies out there that are offering full body MRIs where you can do. Because early detection is such a key sometimes in mitigating a condition, right? Getting cancer in a stage one versus a stage four. Uphill battle. Game changer.

Game changer. Pre-metastasis, right? So, I mean, for my personal, you know, just a quick anecdote on my personal story. Like, I recently did a full body scan with Pranovo and i they found a small lesion on my prostate right so this is my personal story that i haven't shared and immediately all these thoughts come into your head like oh my god what does this mean is it cancer what do i do immediately you know get on the phone with a urologist so you know they found it was half a centimeter, which may or may not be, may or may not become cancer.

But the point is, I've now got a clean bill of health on the rest of the body. I have one area of focus. I will not be caught off guard. I will continue to monitor this and, and, and not beat myself up, keep living my healthy lifestyle,

but check this periodically. And, and, and God god forbid if it ever does become something i've already seen it so early where i have a mitigation amen that is that is great you know so um i end every podcast the same way and there's no sort of right or wrong answer to this question but i ask every guest that comes on the podcast when we wind down um what does it mean to you to be an ultimate human you want to tackle this what does it mean to you to be the ultimate human

it means basically aging gracefully and feeling fantastic i love that you yeah if you don't feel fantastic forget about it i'd rather not be here. Amen. I would just say, I think you touched on it earlier, is in essence, keep accelerating my body to use as much of its resources to be optimized and not borrow from the future. That's great. Later on, I'm not being taxed.

All right. Well, guys, stay tuned. I'm absolutely going to do a follow-up podcast with these guys as some of their research comes to fruition. Some of these clinical studies that they're involved in come to light and get published. I'll definitely keep you guys up to date. I'll put links to their clinic and their products in the show notes below. If you have any questions about those, I'm sure you can contact their team. But as always, that's just science.