Best Friends with Nicole Byer and Sasheer Zamata

Gayle & Oprah. Bonnie & Clyde. Nicole & Sasheer. Enter the pantheon of best friendship. When you’re forced to change your number, are sick of being single, or want to take a pole-dancing class, you’re going to need a best friend...and if you don’t, you can still have this podcast.

158 episodes transcribed
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Comedy

Nicole Hates Mondays

Episode Date: May 20, 2026

What do hundreds of Garfield-themed phones washed ashore and a robbery of 12 tons of Kit Kats have in common? Nicole and Sasheer talk about b...

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Comedy

Nicole Has A Nut Stash

Episode Date: May 13, 2026

This episode, Nicole and Sasheer leave no conversational stone unturned, covering everything from falling in love with chatbots to Baby’...

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Comedy

Sasheer is a Daring Soul

Episode Date: February 18, 2026

Nicole and Sasheer have so much to dish about this week, covering everything from the Black Eyed Peas and Vanilla Ice's decision making...