Best Friends with Nicole Byer and Sasheer Zamata

Gayle & Oprah. Bonnie & Clyde. Nicole & Sasheer. Enter the pantheon of best friendship. When you’re forced to change your number, are sick of being single, or want to take a pole-dancing class, you’re going to need a best friend...and if you don’t, you can still have this podcast.

128 episodes transcribed
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Comedy

Nicole Knows Her Cars

Episode Date: November 19, 2025

Nicole and Sasheer are back with a special solo episode for your video watching eyes and podcast listening ears! They get into Nicole's lates...

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Comedy

Nicole's In Her Pants Era

Episode Date: November 5, 2025

Nicole and Sasheer are back in the studio to debrief Sasheer’s house project, uncover the origin story of cereal mascots, try a new...

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Comedy

Nicole's Fruit Journey

Episode Date: October 22, 2025

Nicole and Sasheer are back from a quick trip to Vegas and ready to break down all of their funniest moments, from seeing Ashlee Simpson to t...

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Comedy

Sasheer Loves Yuzu

Episode Date: September 3, 2025

Nicole and Sasheer have a very special friend joining them today - the wonderful Owen Thiele (Adults, Overcompensating, Theater Camp)! The tr...